keyword
https://read.qxmd.com/read/38537011/effect-of-zro2-paste-surface-treatments-and-storage-on-weibull-characteristics-and-resin-bond-strength-to-zirconia
#1
JOURNAL ARTICLE
Anne Heloyse Teixeira Crispim, Sarah Emille Gomes da Silva, Fernanda Gurgel de Gois Moreira, Bianca Cristina Dantas da Silva, Amanda Maria de Oliveira Dal Piva, Liliana Gressler May, Natália de Freitas Daudt, Rodrigo Othávio Assunção Souza
The objective is to evaluate the effect of different surface treatments and storage on the shear strength of ultratranslucent zirconia. 36 blocks of ultra-translucent zirconia were fabricated (7x7x2mm) and sintered. Then, divided into 12 groups according to the "surface treatment" (C -Primer; Al -Sandblasting with Al2O3 + Primer; Si -Silicate + Primer; Gl -Glaze + HF + Primer; Z -Zirlink; Zp -Zirlink + Primer) and "storage" factors (ST-with 150 days/37º and without). After surface treatment, five cylinders (Ø=2mm; h=2...
2024: Brazilian Dental Journal
https://read.qxmd.com/read/38536648/catheter-ablation-of-ventricular-tachycardia-in-ischemic-heart-disease-what-is-known-and-new-perspectives
#2
REVIEW
Pasquale Valerio Falzone, Sara Vazquez-Calvo, Ivo Roca-Luque
PURPOSE OF THE REVIEW: This review aims to evaluate current evidence regarding ventricular tachycardia ablation in patients with ischemic heart disease and explore novel approaches currently developing to improve procedural and long-term outcomes. RECENT FINDINGS: Recently published trials (PARTITA, PAUSE-SCD, and SURVIVE-VT) have demonstrated the prognostic benefit of prophylactic ventricular tachycardia ablation compared to current clinical practice. Advanced cardiac imaging provides a valuable pre-procedural evaluation of the arrhythmogenic substrate, identifying ablation targets non-invasively...
March 27, 2024: Current Heart Failure Reports
https://read.qxmd.com/read/38536644/hereditary-ttp-upshaw-schulman-syndrome-the-ductus-arteriosus-controls-newborn-survival
#3
REVIEW
Yoshihiro Fujimura
Hereditary TTP (hTTP), termed Upshaw-Schulman syndrome, is an ultra-rare disorder caused by a severe deficiency of plasma ADAMTS13 activity that allows circulation of ultra-large von Willebrand factor (UL-VWF) multimers. The greatest risk for hTTP is in their first days after birth, when 35-50% of patients will have severe hemolysis, jaundice, and thrombocytopenia. It is often fatal without effective treatment. In utero, fetal blood flowing from the pulmonary artery through the ductus arteriosus (DA) to the aorta is under low-shear-force...
March 27, 2024: International Journal of Hematology
https://read.qxmd.com/read/38535932/herbicide-leaching-in-soil-with-different-properties-perspectives-from-commercial-formulations-and-analytical-standards
#4
JOURNAL ARTICLE
Rita de Cássia Araújo de Medeiros, Tatiane Severo Silva, Taliane Maria da Silva Teófilo, Francisca Daniele da Silva, Matheus de Freitas Souza, Ana Beatriz Rocha de Jesus Passos, Bruno Caio Chaves Fernandes, Hamurábi Anizio Lins, Paulo Sergio Fernandes das Chagas, Carolina Malala Martins Souza, Ioná Santos Araújo Holanda, Daniel Valadão Silva
The leaching of herbicides into the soil is essential to control germinating seeds and parts of vegetative weeds. However, herbicide transportation to deeper soil layers can result in groundwater contamination and, consequently, environmental issues. In this research, our objective was to investigate differences in herbicide leaching between commercial formulations and analytical standards using three different soils. Leaching experiments were carried out for diuron, hexazinone, and sulfometuron-methyl herbicides isolated and in binary and ternary mixtures...
March 2, 2024: Toxics
https://read.qxmd.com/read/38535825/comprehensive-analysis-of-bufadienolide-and-protein-profiles-of-gland-secretions-from-medicinal-bufo-species
#5
JOURNAL ARTICLE
Yunge Fang, Liangmian Chen, Pengfei Wang, Yating Liu, Yuxiu Wang, Zhimin Wang, Yue Ma, Huimin Gao
Toad Venom (TV) is the dried product of toxic secretions from Bufo bufo gargarizans Cantor (BgC) or B. melanostictus Schneider (BmS). Given the increasing medical demand and the severe depletion of wild toads, a number of counterfeit TVs appeared on the market, posing challenges to its quality control. In order to develop an efficient, feasible, and comprehensive approach to evaluate TV quality, a thorough analysis and comparison of chemical compounds among legal species BgC and BmS, as well as the main confusion species B...
March 20, 2024: Toxins
https://read.qxmd.com/read/38535793/the-toxicokinetics-excretion-patterns-and-milk-transmission-of-ochratoxin-a-in-lactating-sows
#6
JOURNAL ARTICLE
Qiufeng Zhu, Honglei Qu, Ruifen Kang, Yunduo Zheng, Qiuying Guo, Shimeng Huang, Lihong Zhao, Qiugang Ma
Ochratoxin A (OTA), a mycotoxin commonly found in feedstuffs, is known for its detrimental effects on the kidneys and liver, posing significant health risks to animals and humans. This study investigated the toxicokinetics, excretion patterns, and milk transmission of Ochratoxin A (OTA) in lactating sows. The sows were administered a single oral dose of 500 μg/kg BW (body weight), followed by the systematic sampling of plasma, feces, urine, and milk. Plasma samples were collected at 0, 5, 15, and 30 min, and 1, 2, 3, 6, 9, 12, 24, 48, 72, 88, 96, and 120 h post administration...
March 1, 2024: Toxins
https://read.qxmd.com/read/38535776/chelating-additive-regulating-zn-ion-solvation-chemistry-for-highly-efficient-aqueous-zinc-metal-battery
#7
JOURNAL ARTICLE
Dongming Xu, Xueting Ren, Haoyu Li, Yuran Zhou, Simin Chai, Yining Chen, Hang Li, Lishun Bai, Zhi Chang, Anqiang Pan, Haoshen Zhou
Aqueous zinc-metal batteries (AZMBs) usually suffered from poor reversibility and limited lifespan because of serious water induced side-reactions, hydrogen evolution reactions (HER) and rampant zinc (Zn) dendrite growth. Reducing the content of water molecules within Zn-ion solvation sheaths can effectively suppress those inherent defects of AZMBs. In this work, we originally discovered that the two carbonyl groups of N-Acetyl-ε-caprolactam (N-ac) chelating ligand can serve as dual solvation sites to coordinate with Zn2+, thereby minimizing water molecules within Zn-ion solvation sheaths, and greatly inhibit water-induced side-reactions and HER...
March 27, 2024: Angewandte Chemie
https://read.qxmd.com/read/38535638/three-dimensional-vanadium-and-nitrogen-dual-doped-ti-3-c-2-film-with-ultra-high-specific-capacitance-and-high-volumetric-energy-density-for-zinc-ion-hybrid-capacitors
#8
JOURNAL ARTICLE
Xinhui Jin, Siliang Yue, Jiangcheng Zhang, Liang Qian, Xiaohui Guo
Zinc-ion hybrid capacitors (ZICs) can achieve high energy and power density, ultralong cycle life, and a wide operating voltage window, and they are widely used in wearable devices, portable electronics devices, and other energy storage fields. The design of advanced ZICs with high specific capacity and energy density remains a challenge. In this work, a novel kind of V, N dual-doped Ti3 C2 film with a three-dimensional (3D) porous structure (3D V-, N-Ti3 C2 ) based on Zn-ion pre-intercalation can be fabricated via a simple synthetic process...
March 8, 2024: Nanomaterials
https://read.qxmd.com/read/38535637/effect-of-nitrogen-dopant-agents-in-the-performance-of-graphene-based-cathodes-for-li-s-batteries
#9
JOURNAL ARTICLE
Adrián Licari, Almudena Benítez, Juan Luis Gómez-Cámer, Rafael Trócoli, Álvaro Caballero
Lithium-sulphur (Li-S) batteries offer high energy density compared to lithium-ion batteries, emerging as a promising technology for the next generation of energy storage systems. The ongoing challenge is to improve their electrochemical performance, extend their useful life and mitigate some problems that persist in this technology, by the investigation in materials with diverse properties. This work seeks to elucidate the importance and repercussions associated with functionalisation of graphene-based materials through nitrogen incorporation (more than 9 wt...
March 8, 2024: Nanomaterials
https://read.qxmd.com/read/38535300/comparative-metabolomics-of-ligulate-and-tubular-flowers-of-two-cultivars-of-calendula-officinalis-l
#10
JOURNAL ARTICLE
Vladimir Ossipov, Firdaus Khazieva, Dmitry Baleev, Juha-Pekka Salminen, Nikolay Sidelnikov
Calendula officinalis L. is a well-known plant widely used in traditional medicine due to the presence of various biologically active compounds. The main raw material for the production of medicinal preparations is the inflorescence, which consists of ligulate and tubular flowers. However, the characteristics of the metabolome of these flowers are not fully understood. This study identified and compared the levels of major metabolites in the ligulate and tubular flowers of two C. officinalis cultivars, 'Golden Sea' (GS) and 'Paradise Garden' (PG)...
February 26, 2024: Metabolites
https://read.qxmd.com/read/38535293/integrative-analysis-of-cytokine-and-lipidomics-datasets-following-mild-traumatic-brain-injury-in-rats
#11
JOURNAL ARTICLE
Alexis N Pulliam, Alyssa F Pybus, David A Gaul, Samuel G Moore, Levi B Wood, Facundo M Fernández, Michelle C LaPlaca
Traumatic brain injury (TBI) is a significant source of disability in the United States and around the world and may lead to long-lasting cognitive deficits and a decreased quality of life for patients across injury severities. Following the primary injury phase, TBI is characterized by complex secondary cascades that involve altered homeostasis and metabolism, faulty signaling, neuroinflammation, and lipid dysfunction. The objectives of the present study were to (1) assess potential correlations between lipidome and cytokine changes after closed-head mild TBI (mTBI), and (2) examine the reproducibility of our acute lipidomic profiles following TBI...
February 21, 2024: Metabolites
https://read.qxmd.com/read/38535099/ultra-high-frequency-ecg-in-cardiac-pacing-and-cardiac-resynchronization-therapy-from-technical-concept-to-clinical-application
#12
REVIEW
Uyên Châu Nguyên, Jesse H J Rijks, Filip Plesinger, Leonard M Rademakers, Justin Luermans, Karin C Smits, Antonius M W van Stipdonk, Frits W Prinzen, Kevin Vernooy, Josef Halamek, Karol Curila, Pavel Jurak
Identifying electrical dyssynchrony is crucial for cardiac pacing and cardiac resynchronization therapy (CRT). The ultra-high-frequency electrocardiography (UHF-ECG) technique allows instantaneous dyssynchrony analyses with real-time visualization. This review explores the physiological background of higher frequencies in ventricular conduction and the translational evolution of UHF-ECG in cardiac pacing and CRT. Although high-frequency components were studied half a century ago, their exploration in the dyssynchrony context is rare...
February 23, 2024: Journal of Cardiovascular Development and Disease
https://read.qxmd.com/read/38535077/validation-and-implementation-of-optiview-and-envision-flex-detection-systems-for-immunocytochemical-staining-protocols-of-the-ten-most-commonly-used-diagnostic-markers-in-routine-cytopathological-practice
#13
JOURNAL ARTICLE
Anja Dremelj, Simona Miceska, Anamarija Kuhar, Natasa Nolde, Veronika Kloboves-Prevodnik
The withdrawal of the iView detection system (iV) forced many cytopathology laboratories, including ours, to substitute immunocytochemical (ICC) staining protocols for routine practice with other detection systems. Our objective was to optimize, validate, and implement ICC protocols using OptiView (OV) and EnVision FLEX (EnV) detection systems, comparing the results with those obtained using iV. Residual cytologic samples with known diagnoses were used, testing antibodies for the ten most common markers in routine cytopathology diagnostics (calretinin, Ber-EP4, MOC-31, CKAE1/AE3, CK5/6, CD68, LCA, desmin, HBME-1, and WT1)...
March 21, 2024: Diagnostics
https://read.qxmd.com/read/38535027/detection-of-acute-brain-injury-in-intensive-care-unit-patients-on-ecmo-support-using-ultra-low-field-portable-mri-a-retrospective-analysis-compared-to-head-ct
#14
JOURNAL ARTICLE
Sung-Min Cho, Shivalika Khanduja, Jiah Kim, Jin Kook Kang, Jessica Briscoe, Lori R Arlinghaus, Kha Dinh, Bo Soo Kim, Haris I Sair, Audrey-Carelle N Wandji, Elena Moreno, Glenda Torres, Jose Gavito-Higuera, Huimahn A Choi, John Pitts, Aaron M Gusdon, Glenn J Whitman
Early detection of acute brain injury (ABI) is critical to intensive care unit (ICU) patient management and intervention to decrease major complications. Head CT (HCT) is the standard of care for the assessment of ABI in ICU patients; however, it has limited sensitivity compared to MRI. We retrospectively compared the ability of ultra-low-field portable MR (ULF-pMR) and head HCT, acquired within 24 h of each other, to detect ABI in ICU patients supported on extracorporeal membrane oxygenation (ECMO). A total of 17 adult patients (median age 55 years; 47% male) were included in the analysis...
March 13, 2024: Diagnostics
https://read.qxmd.com/read/38534630/tailoring-hydrogel-structures-investigating-the-effects-of-multistep-cellulose-defibrillation-on-polyvinyl-alcohol-composites
#15
JOURNAL ARTICLE
Gabriel Goetten de Lima, Bruno Bernardi Aggio, Alessandra Cristina Pedro, Tielidy A de M de Lima, Washington Luiz Esteves Magalhães
Defibrillating cellulose through various grinding steps and incorporating it into hydrogels introduces unique properties that warrant thorough exploration. This study investigates cellulose defibrillation at different steps (15-120) using an ultra-fine friction grinder, blended with high-molecular-weight polyvinyl alcohol (PVA), and crosslinked via freeze-thawing. A critical discovery is the influence of defibrillation on the hydrogel structure, as evidenced by reduced crystallinity, thermal degradation, and the enhanced swelling of PVA chains...
March 21, 2024: Gels
https://read.qxmd.com/read/38534257/hydrogel-gated-fets-in-neuromorphic-computing-to-mimic-biological-signal-a-review
#16
REVIEW
Sankar Prasad Bag, Suyoung Lee, Jaeyoon Song, Jinsink Kim
Hydrogel-gated synaptic transistors offer unique advantages, including biocompatibility, tunable electrical properties, being biodegradable, and having an ability to mimic biological synaptic plasticity. For processing massive data with ultralow power consumption due to high parallelism and human brain-like processing abilities, synaptic transistors have been widely considered for replacing von Neumann architecture-based traditional computers due to the parting of memory and control units. The crucial components mimic the complex biological signal, synaptic, and sensing systems...
March 19, 2024: Biosensors
https://read.qxmd.com/read/38534249/ultrasensitive-3d-stacked-silicon-nanosheet-field-effect-transistor-biosensor-with-overcoming-debye-shielding-effect-for-detection-of-dna
#17
JOURNAL ARTICLE
Yinglu Li, Shuhua Wei, Enyi Xiong, Jiawei Hu, Xufang Zhang, Yanrong Wang, Jing Zhang, Jiang Yan, Zhaohao Zhang, Huaxiang Yin, Qingzhu Zhang
Silicon nanowire field effect (SiNW-FET) biosensors have been successfully used in the detection of nucleic acids, proteins and other molecules owing to their advantages of ultra-high sensitivity, high specificity, and label-free and immediate response. However, the presence of the Debye shielding effect in semiconductor devices severely reduces their detection sensitivity. In this paper, a three-dimensional stacked silicon nanosheet FET (3D-SiNS-FET) biosensor was studied for the high-sensitivity detection of nucleic acids...
March 14, 2024: Biosensors
https://read.qxmd.com/read/38534141/the-association-of-intraocular-efavirenz-concentrations-and-hiv-1-viral-load-among-persons-with-hiv
#18
JOURNAL ARTICLE
Yiwen Qian, Pei Zhang, Luoziyi Wang, Jinshan Suo, Lin Yin, Yuceng Wang, Lijun Zhang, Zhiliang Wang
OBJECTIVE: Efavirenz (EFV) is commonly used in combination antiretroviral therapy (cART). However, in our previous study, many persons living with human immunodeficiency virus (HIV) exhibited ocular complications despite undergoing effective cART. Here, we aimed to determine the intraocular EFV concentrations in the vitreous and analyze the factors affecting viral load in the vitreous in patients with HIV-associated retinopathies. DESIGN: Observational, retrospective study...
March 25, 2024: Journal of Acquired Immune Deficiency Syndromes: JAIDS
https://read.qxmd.com/read/38533978/plasma-driven-tuning-of-dielectric-permittivity-in-graphene
#19
JOURNAL ARTICLE
Elena Tatarova, Ana Dias, Plamen Dankov, Jivko Kissovski, Ana Maria Botelho do Rego, Neli Bundaleska, Edgar Felizardo, Miroslav Abrashev, Ana Maria Ferraria, Thomas Strunskus, Vasyl Shvalya, Neelakandan M Santhosh, Ivan Valeriev Ivanov, Martin Košiček, Janez Zavašnik, Luis Lemos Alves, Bruno Gonçalves, Uroš Cvelbar
Materials with tunable negative electromagnetic performance, i.e., where dielectric permittivity becomes negative, have long been pursued in materials research due to their peculiar electromagnetic (EM) characteristics. Here, this promising feature is reported in materials on the case of plasma-synthesized nitrogen-doped graphene sheets with tunable permittivity over a wide (1-40 GHz) frequency range. Selectively incorporated nitrogen atoms in a graphene scaffold tailor the electronic structure in a way that provides an ultra-low energy (0...
March 27, 2024: Small
https://read.qxmd.com/read/38533683/molecular-networking-guided-investigation-of-the-secondary-metabolome-of-four-morus-species-and-their-in-vivo-neuroprotective-potential-for-the-mitigation-of-alzheimer-s-disease
#20
JOURNAL ARTICLE
Nesrine M Hegazi, Tarik A Mohamed, Abeer Salama, Ahmed R Hamed, Hamada H Saad, Ibrahim A Saleh, Eman H Reda, Ahmed A A Elsayed, Mahmoud A A Ibrahim, Paul W Paré, Thomas Efferth, Mohamed-Elamir F Hegazy
Alzheimer's Disease (AD) is a fatal age-related neurodegenerative condition with a multifactorial etiology contributing to 70% of dementia globally. The search for a multi-target agent to hit different targets involved in the pathogenesis of AD is crucial. In the present study, the neuroprotective effects of four Morus extracts were assessed in LPS-induced AD in mice. Among the studied species, M. macroura exhibited a profound effect on alleviating the loss of cognitive function, improved the learning ability, restored the acetylcholine esterase (AChE) levels to normal, and significantly reduced the tumor necrosis factor alpha (TNF-α) brain content in LPS-treated mice...
March 27, 2024: Food & Function
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