keyword
https://read.qxmd.com/read/38627458/an-integrated-method-for-compensating-and-correcting-nonlinear-error-in-five-axis-machining-utilizing-cutter-contacting-point-data
#21
JOURNAL ARTICLE
Liangji Chen, Haohao Xu, Qiang Huang, Pengcheng Wang
In current five-axis computer numerical control (CNC) machining, the use of minute linear path segments as an approximation for the ideal cutter contacting (CC) point trajectory is still prevalent. However, introducing rotation axes leads to a deviation of the actual CC point trajectory from the ideal, resulting in nonlinear errors. An integrated method is proposed in this paper for compensating and correcting both the contour error, associated with the approximation of the part surface by the ideal CC point trajectory and the nonlinear error of the CC point trajectory based on the information in the CC point data...
April 16, 2024: Scientific Reports
https://read.qxmd.com/read/38627450/development-and-validation-of-an-automated-computational-approach-to-grade-immune-effector-cell-associated-hematotoxicity
#22
JOURNAL ARTICLE
Emily C Liang, Kai Rejeski, Teng Fei, Aya Albittar, Jennifer J Huang, Andrew J Portuguese, Qian Wu, Sandeep Raj, Marion Subklewe, Roni Shouval, Jordan Gauthier
Hematologic toxicity frequently complicates chimeric antigen receptor (CAR) T-cell therapy, resulting in significant morbidity and mortality. In an effort to standardize reporting, the European Hematology Association (EHA) and European Society of Blood and Marrow Transplantation (EBMT) devised the immune effector cell-associated hematotoxicity (ICAHT) grading system, distinguishing between early (day 0-30) and late (after day +30) events based on neutropenia depth and duration. However, manual implementation of ICAHT grading criteria is time-consuming and susceptible to subjectivity and error...
April 16, 2024: Bone Marrow Transplantation
https://read.qxmd.com/read/38627089/two-prediction-error-systems-in-the-nonlemniscal-inferior-colliculus-spectral-and-non-spectral
#23
JOURNAL ARTICLE
Guillermo V Carbajal, Lorena Casado-Román, Manuel S Malmierca
According to the predictive processing framework, perception emerges from the reciprocal exchange of predictions and prediction errors (PE) between hierarchically organized neural circuits. The nonlemniscal division of the inferior colliculus (IC) is the earliest source of auditory PE signals, but their neuronal generators, properties and functional relevance have remained mostly undefined. We recorded single-unit mismatch responses to auditory oddball stimulation at different intensities, together with activity evoked by two sequences of alternating tones to control frequency-specific effects...
April 16, 2024: Journal of Neuroscience
https://read.qxmd.com/read/38626938/calculating-the-cost-of-medication-errors-a-systematic-review-of-approaches-and-cost-variables
#24
JOURNAL ARTICLE
Sakunika Ranasinghe, Abarna Nadeshkumar, Savini Senadheera, Nithushi Samaranayake
INTRODUCTION: Medication errors are an unnecessary cost to a healthcare system and patients of a country. This review aimed to systematically identify published cost variables used to calculate the cost of medication errors and to explore any updates on findings already known on calculating the cost of medication errors during the past 10 years. METHODS: A systematic review was conducted according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines...
April 16, 2024: BMJ Open Quality
https://read.qxmd.com/read/38626929/systematic-review-of-the-effects-of-patient-errors-using-inhaled-delivery-systems-on-clinical-outcomes-in-copd
#25
JOURNAL ARTICLE
David M G Halpin, Donald A Mahler
BACKGROUND: Errors using inhaled delivery systems for COPD are common and it is assumed that these lead to worse clinical outcomes. Previous systematic reviews have included patients with both asthma and COPD and much of the evidence related to asthma. More studies in COPD have now been published. Through systematic review, the relationship between errors using inhalers and clinical outcomes in COPD, including the importance of specific errors, was assessed.MethodsElectronic databases were searched on 27 October 2023 to identify cohort, case-control or randomised controlled studies, which included patients with COPD, an objective assessment of inhaler errors and data on at least one outcome of interest (forced expiratory volume in 1 s, (FEV1 ), dyspnoea, health status and exacerbations)...
April 16, 2024: BMJ Open Respiratory Research
https://read.qxmd.com/read/38626381/determination-of-the-hammett-acidity-of-hf-base-reagents
#26
JOURNAL ARTICLE
Mélissa Longuet, Kassandra Vitse, Agnès Martin-Mingot, Bastien Michelet, Frédéric Guégan, Sébastien Thibaudeau
Harnessing the acidity of HF/base reagents is of paramount importance to improve the efficiency and selectivity of fluorination reactions. Yet, no general method has been reported to evaluate their acidic properties, and experimental designs are still relying on a trial-and-error approach. We report a new method based on 19 F NMR spectroscopy which allows highly sensitive measures and short-time analyses. Advantageously, the basic properties of the indicators can be determined upstream by DFT calculations, affording a simple yet robust semiempirical approach...
April 16, 2024: Journal of the American Chemical Society
https://read.qxmd.com/read/38625988/age-at-natural-menopause-and-its-determinants-in-female-population-of-kharameh-cohort-study-comparison-of-regression-conditional-tree-and-forests
#27
JOURNAL ARTICLE
Zahra Pasokh, Mozhgan Seif, Haleh Ghaem, Abbas Rezaianzadeh, Masoumeh Ghoddusi Johari
BACKGROUND: Natural menopause is defined as the permanent cessation of menstruation that occurs after 12 consecutive months of amenorrhea without any obvious pathological or physiological cause. The age of this phenomenon has been reported to be associated with several health outcomes. OBJECTIVES: This study aimed to estimate the Age at Natural Menopause (ANM) and to identify reproductive and demographic factors affecting ANM. METHODS: This cross-sectional, population-based study was conducted on 2517 post-menopausal women aged 40-70 years participating in the first phase of the PERSIAN cohort study of Kharameh, Iran, during 2014-2017...
2024: PloS One
https://read.qxmd.com/read/38625224/does-ifrs-information-on-tax-loss-carryforwards-and-negative-performance-improve-predictions-of-earnings-and-cash-flows
#28
JOURNAL ARTICLE
Sandra Dreher, Sebastian Eichfelder, Felix Noth
UNLABELLED: We analyze the usefulness of accounting information on tax loss carryforwards and negative performance to predict earnings and cash flows. We use hand-collected information on tax loss carryforwards and corresponding deferred taxes from the International Financial Reporting Standards tax footnotes for listed firms from Germany. Our out-of-sample tests show that considering accounting information on tax loss carryforwards does not enhance performance forecasts and typically even worsens predictions...
April 29, 2023: J Bus Econ
https://read.qxmd.com/read/38625012/potential-of-gpt-4-for-detecting-errors-in-radiology-reports-implications-for-reporting-accuracy
#29
JOURNAL ARTICLE
Roman Johannes Gertz, Thomas Dratsch, Alexander Christian Bunck, Simon Lennartz, Andra-Iza Iuga, Martin Gunnar Hellmich, Thorsten Persigehl, Lenhard Pennig, Carsten Herbert Gietzen, Philipp Fervers, David Maintz, Robert Hahnfeldt, Jonathan Kottlors
Background Errors in radiology reports may occur because of resident-to-attending discrepancies, speech recognition inaccuracies, and large workload. Large language models, such as GPT-4 (ChatGPT; OpenAI), may assist in generating reports. Purpose To assess effectiveness of GPT-4 in identifying common errors in radiology reports, focusing on performance, time, and cost-efficiency. Materials and Methods In this retrospective study, 200 radiology reports (radiography and cross-sectional imaging [CT and MRI]) were compiled between June 2023 and December 2023 at one institution...
April 2024: Radiology
https://read.qxmd.com/read/38625006/data-extraction-from-free-text-reports-on-mechanical-thrombectomy-in-acute-ischemic-stroke-using-chatgpt-a-retrospective-analysis
#30
JOURNAL ARTICLE
Nils C Lehnen, Franziska Dorn, Isabella C Wiest, Hanna Zimmermann, Alexander Radbruch, Jakob Nikolas Kather, Daniel Paech
Background Procedural details of mechanical thrombectomy in patients with ischemic stroke are important predictors of clinical outcome and are collected for prospective studies or national stroke registries. To date, these data are collected manually by human readers, a labor-intensive task that is prone to errors. Purpose To evaluate the use of the large language models (LLMs) GPT-4 and GPT-3.5 to extract data from neuroradiology reports on mechanical thrombectomy in patients with ischemic stroke. Materials and Methods This retrospective study included consecutive reports from patients with ischemic stroke who underwent mechanical thrombectomy between November 2022 and September 2023 at institution 1 and between September 2016 and December 2019 at institution 2...
April 2024: Radiology
https://read.qxmd.com/read/38624003/-corrigendum-mir%C3%A2-146b%C3%A2-5p-inhibits-tumorigenesis-and-metastasis-of-gallbladder-cancer-by-targeting-toll%C3%A2-like-receptor%C3%A2-4-via-the-nuclear-factor%C3%A2-%C3%AE%C2%BAb-pathway
#31
Bin Ouyang, Ningfeng Pan, Haifeng Zhang, Chuanming Xing, Wu Ji
Following the publication of the article, the authors drew to the Editor's attention that, in Fig. 4D on p. 7, the data correctly shown to represent the E‑cadherin bands for the "NOZ" experiment had inadvertently been used to show the Vimentin bands. However, the authors retained their original data, and the corrected version of Fig. 4, now showing the correct data for the Vimentin bands in Fig. 4D for the "NOZ" experiment, is shown on the next page. Note that this error did not grossly affect either the results or the conclusions reported in this work...
March 2024: Oncology Reports
https://read.qxmd.com/read/38623712/long-term-personalized-high-protein-high-fat-diet-in-pediatric-patients-with-glycogen-storage-disease-type-iiia-evaluation-of-myopathy-metabolic-control-physical-activity-growth-and-dietary-compliance
#32
JOURNAL ARTICLE
Sema Kalkan Uçar, Yasemin Atik Altınok, Yelda Mansuroglu, Ebru Canda, Havva Yazıcı, Merve Yoldaş Çelik, Fehime Erdem, Ayşe Yüksel Yanbolu, Zülal Ülger, Mahmut Çoker
Dietary lipid manipulation has recently been proposed for managing glycogen storage disease (GSD) type IIIa. This study aimed to evaluate the myopathic, cardiac, and metabolic status, physical activity, growth, and dietary compliance of a personalized diet high in protein and fat for 24 months. Of 31 patients with type IIIa GSD, 12 met the inclusion criteria. Of these, 10 patients (mean age 11.2 ± 7.4 years) completed the study. Patients were prescribed a personalized high-protein, high-fat diet, comprising 3...
April 16, 2024: Journal of Inherited Metabolic Disease
https://read.qxmd.com/read/38623636/a-new-patient-reported-outcomes-measure-for-surgically-treated-epiphora-tearing-assessment-and-rating-scale-12-tears-12
#33
JOURNAL ARTICLE
Aria Jafari, Jonathan C Simmonds, Margaret B Mitchell, Catherine G Banks, Ashton Lehmann, Marianella Paz-Lansberg, Michael K Yoon, Ralph Metson
BACKGROUND: No widely accepted, validated instrument currently exists to measure clinical outcomes in patients who undergo dacryocystorhinostomy (DCR) for treatment of epiphora. OBJECTIVE: To develop a patient-reported outcome measure applicable to this population. METHODS: Psychometric evaluations, consultation with experts, and review of the literature informed item generation of a 12-question questionnaire to incorporate the most relevant symptoms experienced by patients with nasolacrimal duct obstruction...
April 16, 2024: American Journal of Rhinology & Allergy
https://read.qxmd.com/read/38622837/congenital-disorders-of-glycosylation-with-multiorgan-disruption-and-immune-dysregulation-caused-by-compound-heterozygous-variants-in-man2b2
#34
JOURNAL ARTICLE
Shiqi Fan, Huanhuan Wu, Rongrong Wang, Qian Chen, Xue Zhang
BACKGROUND: Congenital disorders of glycosylation (CDG) are a type of inborn error of metabolism (IEM) resulting from defects in glycan synthesis or failed attachment of glycans to proteins or lipids. One rare type of CDG is caused by homozygous or compound heterozygous loss-of-function variants in mannosidase alpha class 2B member 2 (MAN2B2). To date, only two cases of MAN2B2-CDG have been reported worldwide. METHODS: Trio whole-exome sequencing (Trio-WES) was conducted to screen for candidate variants...
April 2024: Molecular Genetics & Genomic Medicine
https://read.qxmd.com/read/38622597/observed-rates-of-surgical-instrument-errors-point-to-visualization-tasks-as-being-a-critically-vulnerable-point-in-sterile-processing-and-a-significant-cause-of-lost-chargeable-or-minutes
#35
JOURNAL ARTICLE
Peter F Nichol, Mark J Saari, Natalia Navas, David Aguilar, Rita K Bliesner, Paige J Brunner, Jacob C Caceres, Madelyn Chen, Ava R VanDommelen, Matthew Fischer, Simar Garcha, Elaf A Ghawas, Grace R Hackinson, Ava Hitzeman, Maria Jabbour, Amanda M Jentsch, Madison M Kurth, Mollyn Leyden, Qianyun Luo, Abigail C McGrain, Gwendolyn Nytes, Olivia R O'Brien, Jesibell K Philavong, Natalie Villegas, Shannon R Walsh, Sydney S Wisdorf
BACKGROUND: The reporting of surgical instrument errors historically relies on cumbersome, non-automated, human-dependent, data entry into a computer database that is not integrated into the electronic medical record. The limitations of these reporting systems make it difficult to accurately estimate the negative impact of surgical instrument errors on operating room efficiencies. We set out to determine the impact of surgical instrument errors on a two-hospital healthcare campus using independent observers trained in the identification of Surgical Instrument Errors...
April 15, 2024: BMC Surgery
https://read.qxmd.com/read/38622474/kasp-a-high-throughput-genotyping-system-and-its-applications-in-major-crop-plants-for-biotic-and-abiotic-stress-tolerance
#36
REVIEW
Bhawna Dipta, Salej Sood, Vikas Mangal, Vinay Bhardwaj, Ajay Kumar Thakur, Vinod Kumar, Brajesh Singh
Advances in plant molecular breeding have resulted in the development of new varieties with superior traits, thus improving the crop germplasm. Breeders can screen a large number of accessions without rigorous and time-consuming phenotyping by marker-assisted selection (MAS). Molecular markers are one of the most imperative tools in plant breeding programmes for MAS to develop new cultivars possessing multiple superior traits. Single nucleotide polymorphisms (SNPs) are ideal for MAS due to their low cost, low genotyping error rates, and reproducibility...
April 15, 2024: Molecular Biology Reports
https://read.qxmd.com/read/38622303/energy-big-data-abnormal-cluster-detection-method-based-on-redundant-convolution-codec
#37
JOURNAL ARTICLE
Rui Ma, Zhenhua Yan, Jia Liu, Wenni Kang, Dongge Zhu
Due to the scattered distribution and poor clustering of abnormal clusters in energy big data, the ability to detect anomalies is poor. Therefore, a high-energy data anomaly clustering detection method based on redundant convolutional encoding is proposed. Quantitative analysis of the coupling characteristics of electrical thermal gas optical time series for multi energy users based on Copula function, and incorporating quantitative values into multi energy feature indicators to extract the energy consumption behavior characteristics of multi energy users...
April 15, 2024: Scientific Reports
https://read.qxmd.com/read/38622279/complexity-calibrated-benchmarks-for-machine-learning-reveal-when-prediction-algorithms-succeed-and-mislead
#38
JOURNAL ARTICLE
Sarah E Marzen, Paul M Riechers, James P Crutchfield
Recurrent neural networks are used to forecast time series in finance, climate, language, and from many other domains. Reservoir computers are a particularly easily trainable form of recurrent neural network. Recently, a "next-generation" reservoir computer was introduced in which the memory trace involves only a finite number of previous symbols. We explore the inherent limitations of finite-past memory traces in this intriguing proposal. A lower bound from Fano's inequality shows that, on highly non-Markovian processes generated by large probabilistic state machines, next-generation reservoir computers with reasonably long memory traces have an error probability that is at least <mml:math xmlns:mml="https://www...
April 16, 2024: Scientific Reports
https://read.qxmd.com/read/38622212/dynamic-mechanical-response-and-crack-evolution-law-of-raw-coal-loaded-by-dynamic-static-coupling-under-three-dimensional-constraints
#39
JOURNAL ARTICLE
ShunKun Zhao, ShanYang Wei, Lin Zhang, Xianggui Tian, XingZhuan Yang, Xing Wang
This paper presents the investigation of the dynamic mechanical properties of coal rock under complex stress conditions at depth, based on the improved Separate Hopkinson Pressure Bar Test System. A total of 15 groups of coal samples were used to perform dynamic impact tests under different conditions. The changing rules of dynamic strength, crushing, fractal dimension and damage modes of coal under different stress conditions were analyzed. A total of nine groups of coal samples were selected for numerical simulation using ANSYS/LS-DYNA...
April 15, 2024: Scientific Reports
https://read.qxmd.com/read/38622211/empagliflozin-in-children-with-glycogen-storage-disease-associated-inflammatory-bowel-disease-a-prospective-single-arm-open-label-clinical-trial
#40
JOURNAL ARTICLE
Zhiling Li, Xiaoyan Zhang, Huan Chen, Hanshi Zeng, Jiaxing Wu, Ying Wang, Ni Ma, Jiaoli Lan, Yuxin Zhang, Huilin Niu, Lei Shang, Xun Jiang, Min Yang
Glycogen storage disease type Ib (GSD-Ib) is a rare inborn error of glycogen metabolism caused by mutations in SLC37A4. Patients with GSD-Ib are at high risk of developing inflammatory bowel disease (IBD). We evaluated the efficacy of empagliflozin, a renal sodium‒glucose cotransporter protein 2 (SGLT2) inhibitor, on colonic mucosal healing in patients with GSD-associated IBD. A prospective, single-arm, open-label clinical trial enrolled eight patients with GSD-associated IBD from Guangdong Provincial People's Hospital in China from July 1, 2022 through December 31, 2023...
April 15, 2024: Scientific Reports
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