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https://www.readbyqxmd.com/read/28439723/psychiatric-comorbidity-in-alcohol-use-disorders-results-from-the-german-s3-guidelines
#1
REVIEW
U W Preuss, E Gouzoulis-Mayfrank, U Havemann-Reinecke, I Schäfer, M Beutel, E Hoch, K F Mann
Alcohol use disorders (AUD) have a high comorbidity with mental disorders. Vice versa, alcohol consumption plays an important role in affective disorders, anxiety disorders, ADHD, schizophrenic psychosis, and other mental disorders. In developing the current interdisciplinary, evidence-based treatment guideline on screening, diagnostics, and treatment of AUD, available research on comorbid mental diseases in AUD has been compiled to generate recommendations for treatment. The guideline was prepared under the responsibility of the German Association for Psychiatry, Psychotherapy, and Psychosomatics (DGPPN) and the German Association for Addiction Research and Therapy (DG-Sucht)...
April 24, 2017: European Archives of Psychiatry and Clinical Neuroscience
https://www.readbyqxmd.com/read/28439100/ventral-striatal-regulation-of-crem-mediates-impulsive-action-and-drug-addiction-vulnerability
#2
M L Miller, Y Ren, H Szutorisz, N A Warren, C Tessereau, G Egervari, A Mlodnicka, M Kapoor, B Chaarani, C V Morris, G Schumann, H Garavan, A M Goate, M J Bannon, J M Halperin, Y L Hurd
Impulsivity, a multifaceted behavioral hallmark of attention-deficit/hyperactivity disorder (ADHD), strongly influences addiction vulnerability and other psychiatric disorders that incur enormous medical and societal burdens yet the neurobiological underpinnings linking impulsivity to disease remain poorly understood. Here we report the critical role of ventral striatal cAMP-response element modulator (CREM) in mediating impulsivity relevant to drug abuse vulnerability. Using an ADHD rat model, we demonstrate that impulsive animals are neurochemically and behaviorally more sensitive to heroin and exhibit reduced Crem expression in the nucleus accumbens core...
April 25, 2017: Molecular Psychiatry
https://www.readbyqxmd.com/read/28433949/the-dimensional-structure-of-psychopathology-in-22q11-2-deletion-syndrome
#3
Maria Niarchou, Tyler M Moore, Sunny X Tang, Monica E Calkins, Donna M McDonald-McGuinn, Elaine H Zackai, Beverly S Emanuel, Ruben C Gur, Raquel E Gur
BACKGROUND: 22q11.2 Deletion Syndrome (22q11.2DS) is one of the strongest known genetic risk factors for developing schizophrenia. Individuals with 22q11.2DS have high rates of neurodevelopmental disorders in childhood, while in adulthood ∼25% develop schizophrenia. Similar to the general population, high rates of comorbidity are common in 22q11.2DS. Employing a dimensional approach where psychopathology is examined at the symptom-level as complementary to diagnostic categories in a population at such high genetic risk for schizophrenia can help gain a better understanding of how psychopathology is structured as well as its genetic underpinnings...
April 15, 2017: Journal of Psychiatric Research
https://www.readbyqxmd.com/read/28420972/multi-modal-multi-measure-and-multi-class-discrimination-of-adhd-with-hierarchical-feature-extraction-and-extreme-learning-machine-using-structural-and-functional-brain-mri
#4
Muhammad Naveed Iqbal Qureshi, Jooyoung Oh, Beomjun Min, Hang Joon Jo, Boreom Lee
Structural and functional MRI unveil many hidden properties of the human brain. We performed this multi-class classification study on selected subjects from the publically available attention deficit hyperactivity disorder ADHD-200 dataset of patients and healthy children. The dataset has three groups, namely, ADHD inattentive, ADHD combined, and typically developing. We calculated the global averaged functional connectivity maps across the whole cortex to extract anatomical atlas parcellation based features from the resting-state fMRI (rs-fMRI) data and cortical parcellation based features from the structural MRI (sMRI) data...
2017: Frontiers in Human Neuroscience
https://www.readbyqxmd.com/read/28418789/transitions-and-motivations-for-substance-misuse-in-prison-inmates-with-adhd-and-conduct-disorder-validation-of-a-new-instrument
#5
Susan Young, Rafael A González, Kim Wolff, Laura Mutch, Isabella Malet-Lambert, Gisli H Gudjonsson
OBJECTIVE: There is a reasonable theoretical base for understanding the possible causes and motivations behind substance misuse and its dependency. There is a need for a reliable and valid measure that delineates the markers of substance use from its initiation and identifies different motivations for drug use transitioning, maintenance, and dependency. We addressed this gap in the United Kingdom by examining and validating the Substance Transitions in Addiction Rating Scale (STARS). METHODS: For this review, 390 male prisoners were screened for conduct disorder and assessed with a clinical diagnostic interview for attention deficit/hyperactivity disorder (ADHD)...
April 18, 2017: Journal of Dual Diagnosis
https://www.readbyqxmd.com/read/28406942/the-brain-anatomy-of-attention-deficit-hyperactivity-disorder-in-young-adults-a-magnetic-resonance-imaging-study
#6
Jean-G Gehricke, Frithjof Kruggel, Tanyaporn Thampipop, Sharina Dyan Alejo, Erik Tatos, James Fallon, L Tugan Muftuler
BACKGROUND: This is one of the first studies to examine the structural brain anatomy and connectivity associated with an ADHD diagnosis and child as well as adult ADHD symptoms in young adults. It was hypothesized that an adult ADHD diagnosis and in particular childhood symptoms, are associated with widespread changes in the brain macro- and microstructure, which can be used to develop a morphometric biomarker for ADHD. METHODS: Voxel-wise linear regression models were used to examine structural and diffusion-weighted MRI data in 72 participants (31 young adults with ADHD and 41 controls without ADHD) in relation to diagnosis and the number of self-reported child and adult symptoms...
2017: PloS One
https://www.readbyqxmd.com/read/28405786/maternal-responsiveness-as-a-predictor-of-self-regulation-development-and-attention-deficit-hyperactivity-symptoms-across-preschool-ages
#7
Ursula Pauli-Pott, Susan Schloß, Katja Becker
Preschool-age "hot" executive function capacity (i.e. reward-related effortful control) represents an early kind of self-regulation that is involved in social adjustment development as well as the development of subtypes of attention-deficit/hyperactivity disorder (ADHD). Early self-regulation development might be malleable by responsive parenting. We analyzed whether maternal responsiveness/sensitivity predicts reward-related control (RRC) development within the preschool period, and whether RRC mediates a negative link between maternal responsiveness and ADHD symptoms...
April 12, 2017: Child Psychiatry and Human Development
https://www.readbyqxmd.com/read/28398986/living-with-symptoms-of-attention-deficit-hyperactivity-disorder-in-adulthood-a-systematic-review-of-qualitative-evidence
#8
Merete B Bjerrum, Preben U Pedersen, Palle Larsen
BACKGROUND: Attention deficit hyperactivity disorder (ADHD) relates to four dimensions of behavior: inattentiveness, restlessness, impulsiveness and hyperactivity. Symptoms affect multiple areas of daily life such as academic performance and social functioning. Despite the negative effects of ADHD, people diagnosed with ADHD do not necessarily regard themselves as being impaired. However, it is unclear how adults with ADHD experience and manage their symptoms. OBJECTIVES: To identify and synthesize the best available evidence on how adults experience living with ADHD...
April 2017: JBI Database of Systematic Reviews and Implementation Reports
https://www.readbyqxmd.com/read/28390269/validity-and-reliability-of-the-attention-deficit-hyperactivity-disorder-self-report-scale-asrs-v1-1-in-a-clinical-sample-with-eating-disorders
#9
Samantha Carlucci, Iryna Ivanova, Hany Bissada, Giorgio A Tasca
Individuals with eating disorders (EDs) commonly experience comorbid attention deficit hyperactivity disorder (ADHD). The shared features of EDs and ADHD, such as inattention, impulsivity and hyperactivity, may exacerbate ED symptomatology and pose challenges to treatment. It is important to screen patients with EDs for symptoms of ADHD to optimize their treatment outcomes. However, the psychometrics of common measures of ADHD have not yet been examined within an ED population. An example of such a measure is the ADHD self-report scale (ASRS-v1...
March 30, 2017: Eating Behaviors
https://www.readbyqxmd.com/read/28387843/child-executive-control-as-a-moderator-of-the-longitudinal-association-between-sleep-problems-and-subsequent-attention-deficit-hyperactivity-disorder-symptoms
#10
Katherine M Kidwell, Maren Hankey, Jennifer Mize Nelson, Kimberly Andrews Espy, Timothy D Nelson
To examine the longitudinal associations among sleep, executive control (EC), and attention-deficit/hyperactivity disorder (ADHD) symptoms in childhood.  In this longitudinal study ( N  = 271), parents answered questions about sleep problems when children were 3 years old, children completed a comprehensive EC task battery at 4.5 years, and teachers completed standardized measures of child ADHD symptoms in 4th grade.  Latent moderated structural equation models demonstrated that sleep problems at 3 years and EC deficits at 4...
April 6, 2017: Journal of Pediatric Psychology
https://www.readbyqxmd.com/read/28383930/sluggish-cognitive-tempo-in-adults-psychometric-validation-of-the-adult-concentration-inventory
#11
Stephen P Becker, G Leonard Burns, Annie A Garner, Matthew A Jarrett, Aaron M Luebbe, Jeffery N Epstein, Erik G Willcutt
As interest in sluggish cognitive tempo (SCT) increases, a primary limitation for the field is the lack of a unified set of symptoms for assessing SCT. No existing SCT measure includes all items identified in a recent meta-analysis as optimal for distinguishing between SCT and attention-deficit/hyperactivity disorder (ADHD) inattention. This study evaluates a new self-report measure for assessing SCT in adulthood, the Adult Concentration Inventory (ACI), which was developed in response to the meta-analytic findings for assessing SCT...
April 6, 2017: Psychological Assessment
https://www.readbyqxmd.com/read/28375718/trait-impulsivity-and-the-externalizing-spectrum
#12
Theodore P Beauchaine, Aimee R Zisner, Colin L Sauder
This article reviews evidence that trait impulsivity-expressed early in life as the hyperactive-impulsive and combined presentations of attentiondeficit/hyperactivity disorder (ADHD)-is a bottom-up, subcortically mediated vulnerability to all externalizing disorders. This vulnerability arises from deficient mesolimbic dopamine responding, which imbues psychological states (irritability, discontentment) that motivate excessive approach behavior (hyperactivity, impulsivity). Through complex interactions with (a) aversive motivational states that arise from largely independent subcortical systems, (b) emotion regulatory mechanisms that arise from top-down, cortical modulation of subcortical neural function, and (c) environmental risk factors that shape and maintain emotion dysregulation, trait impulsivity confers vulnerability to increasingly severe externalizing behaviors across development...
March 30, 2017: Annual Review of Clinical Psychology
https://www.readbyqxmd.com/read/28371946/-qualit%C3%A3-tsmessung-bei-der-behandlung-von-kindern-und-jugendlichen-mit-entwicklungsst%C3%A3-rungen-eine-machbarkeitsstudie-am-beispiel-adhs
#13
Marta Ulusoy, Peter Borusiak, Karin A Hameister, Max Geraedts
The question of a possible presence of attention deficit/hyperactivity disorder (ADHD) is raised with increasing frequency in pediatric practice. There are guidelines and expert recommendations for diagnostic approaches. But there are no instruments available to evaluate the structural, process and outcome quality. In this pilot study, a set of quality indicators on the treatment quality of ADHD was analyzed in terms of their feasibility in tertiary referral centers.A set of 39 quality indicators (QI) on ADHD developed in advance in a multistage procedure was assessed at 9 tertiary referral centers, with a focus on process verifiability and feasibility...
April 3, 2017: Das Gesundheitswesen
https://www.readbyqxmd.com/read/28363151/irritability-in-adhd-associations-with-depression-liability
#14
Olga Eyre, Kate Langley, Argyris Stringaris, Ellen Leibenluft, Stephan Collishaw, Anita Thapar
BACKGROUND: Irritability and the new DSM-5 diagnostic category of Disruptive Mood Dysregulation Disorder (DMDD) have been conceptualised as related to mood disorder. Irritability is common in Attention Deficit Hyperactivity Disorder (ADHD) but little is known about its association with depression risk in this group. This study aims to establish levels of irritability and prevalence of DMDD in a clinical sample of children with ADHD, and examine their association with anxiety, depression and family history of depression...
March 25, 2017: Journal of Affective Disorders
https://www.readbyqxmd.com/read/28363086/phenomenology-of-hoarding-in-children-with-comorbid-attention-deficit-hyperactivity-disorder-adhd-the-perceptions-of-parents
#15
Fiona A Lynch, Richard Moulding, Jane A McGillivray
Individuals with ADHD and comorbid hoarding disorder are vulnerable to severe consequences from hoarding symptoms. Despite this, and the early onset of hoarding disorder, the nature of hoarding symptoms in children with comorbid ADHD is unknown. We therefore explored the phenomenology of hoarding symptoms among ten 8-12year olds with ADHD and clinically significant hoarding symptoms through parental perceptions. Parents completed in-depth semi-structured interviews. The data was analyzed using Interpretative Phenomenological Analysis...
March 16, 2017: Comprehensive Psychiatry
https://www.readbyqxmd.com/read/28361338/maternal-executive-functioning-and-scaffolding-in-families-of-children-with-and-without-parent-reported-adhd
#16
Heather Mazursky-Horowitz, Sharon R Thomas, Kelsey E Woods, Jeffrey S Chrabaszcz, Kirby Deater-Deckard, Andrea Chronis-Tuscano
Parental scaffolding robustly predicts child developmental outcomes, including improved self-regulation and peer relationships and fewer externalizing behaviors. However, few studies have examined parental characteristics associated with a parent's ability to scaffold. Executive functioning (EF) may be an important individual difference factor associated with maternal scaffolding that has yet to be examined empirically. Scaffolding may be particularly important for children with attention-deficit/hyperactivity disorder (ADHD) and disruptive behavior disorder (DBD) symptoms due to their core difficulties with inattention, disorganization, EF, and self-regulation, their need for greater parental structure, and higher-than-average rates of parental EF deficits...
March 30, 2017: Journal of Abnormal Child Psychology
https://www.readbyqxmd.com/read/28356743/dynamic-balance-in-children-with-attention-deficit-hyperactivity-disorder-and-its-relationship-with-cognitive-functions-and-cerebellum
#17
Michal Goetz, Jaroslava Paulasova Schwabova, Zdenek Hlavka, Radek Ptacek, Craig Bh Surman
BACKGROUND: Attention-deficit hyperactivity disorder (ADHD) is linked to the presence of motor deficiencies, including balance deficits. The cerebellum serves as an integrative structure for balance control and is also involved in cognition, including timing and anticipatory regulation. Cerebellar development may be delayed in children and adolescents with ADHD, and inconsistent reaction time is commonly seen in ADHD. We hypothesized that dynamic balance deficits would be present in children with ADHD and they would correlate with attention and cerebellar functions...
2017: Neuropsychiatric Disease and Treatment
https://www.readbyqxmd.com/read/28355928/measurement-properties-of-mental-health-literacy-tools-measuring-help-seeking-a-systematic-review
#18
Yifeng Wei, Patrick J McGrath, Jill Hayden, Stan Kutcher
BACKGROUND: Mental health literacy is important to improve help-seeking behaviors. However, the quality of mental health help-seeking tools remains unknown. AIMS: We conducted a systematic review to appraise the quality of such tools. METHODS: We searched databases for English publications addressing psychometrics of help-seeking tools. We included help-seeking tools addressing mental health in general and tools on four mental disorders: anxiety, depression, attention deficit hyperactivity disorder (ADHD) and schizophrenia...
March 30, 2017: Journal of Mental Health
https://www.readbyqxmd.com/read/28353182/an-international-qualitative-study-of-ability-and-disability-in-adhd-using-the-who-icf-framework
#19
Soheil Mahdi, Marisa Viljoen, Rafael Massuti, Melissa Selb, Omar Almodayfer, Sunil Karande, Petrus J de Vries, Luis Rohde, Sven Bölte
This is the third in a series of four cross-cultural empirical studies designed to develop International Classification of Functioning, Disability and Health (ICF, and Children and Youth version, ICF(-CY) Core Sets for Attention-Deficit Hyperactivity Disorder (ADHD). To explore the perspectives of individuals diagnosed with ADHD, self-advocates, immediate family members and professional caregivers on relevant areas of impairment and functional abilities typical for ADHD across the lifespan as operationalized by the ICF(-CY)...
March 28, 2017: European Child & Adolescent Psychiatry
https://www.readbyqxmd.com/read/28337734/diffusion-tensor-imaging-dti-findings-in-adult-civilian-military-and-sport-related-mild-traumatic-brain-injury-mtbi-a-systematic-critical-review
#20
Breton Michael Asken, Steven T DeKosky, James R Clugston, Michael S Jaffee, Russell M Bauer
This review seeks to summarize diffusion tensor imaging (DTI) studies that have evaluated structural changes attributed to the mechanisms of mild traumatic brain injury (mTBI) in adult civilian, military, and athlete populations. Articles from 2002 to 2016 were retrieved from PubMed/MEDLINE, EBSCOhost, and Google Scholar, using a Boolean search string containing the following terms: "diffusion tensor imaging", "diffusion imaging", "DTI", "white matter", "concussion", "mild traumatic brain injury", "mTBI", "traumatic brain injury", and "TBI"...
March 24, 2017: Brain Imaging and Behavior
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