keyword
https://read.qxmd.com/read/38430152/rare-sagittal-compensatory-balance-in-neuromuscular-scoliosis-complicated-by-hydrocephalus-a-case-report
#21
JOURNAL ARTICLE
Jingxuan Wang, Zheng Zhang, Shuo Yuan
OBJECTIVE: This case report aims to present a rare case of thoracic lordosis and lumbar kyphosis and describe the posterior instrumented scoliosis correction performed. CASE PRESENTATION: A 59-year-old female presented with low back pain. She had undergone ventriculoperitoneal shunt placement 8 years ago. I scored 76 on the Wechsler Adult Intelligence Scale. MRI of the lumbar spine showed spinal canal stenosis at L3/4, L4/5, and L5/S1. Full spine X-ray revealed thoracic lordosis and lumbar kyphoscoliosis, the coronal imbalance, and the sagittal compensatory balance...
March 1, 2024: Alternative Therapies in Health and Medicine
https://read.qxmd.com/read/38427363/precision-errors-and-monitoring-time-interval-in-pediatric-muscle-imaging-and-neuromuscular-performance-assessment
#22
JOURNAL ARTICLE
Yuwen Zheng, Joel L Lanovaz, James J D Johnston, Saija A Kontulainen
OBJECTIVES: To determine precision errors and monitoring time intervals in imaged muscle properties and neuromuscular performance, and to explore growth-related factors associated with precision errors in children. METHODS: We included 35 children (mean age 10.5yrs) in the precision study cohort and 40 children (10.7yrs) in the follow-up study cohort. We assessed forearm and lower leg muscle properties (area, density) with peripheral quantitative computed tomography...
March 1, 2024: Journal of Musculoskeletal & Neuronal Interactions
https://read.qxmd.com/read/38420967/validity-and-reliability-of-the-dutch-version-of-the-s3-niv-questionnaire-to-evaluate-long-term-noninvasive-ventilation
#23
JOURNAL ARTICLE
Charlotte Gw Seijger, Bettine Ah Vosse, Leandre la Fontaine, Tim Raveling, Nicolle Am Cobben, Peter J Wijkstra
OBJECTIVES: Noninvasive ventilation (NIV) is an effective treatment for chronic respiratory failure (CRF). Patient-centered outcomes need to be evaluated regularly and the S3 -NIV questionnaire seems an applicable tool. We translated this short, self-administered questionnaire into a Dutch version and tested its construct validity and reliability. METHODS: An observational study was conducted, including 127 stable long-term NIV users with CRF or complex sleep related breathing disorders due to different underlying diseases: chronic obstructive pulmonary disease (25%), slowly progressive neuromuscular disorders (35%), rapidly progressive neuromuscular disorders (12%) and 'other disorders' (28%) including complex sleep apnea and obesity hypoventilation syndrome...
2024: Chronic Respiratory Disease
https://read.qxmd.com/read/38420074/the-first-known-case-of-hereditary-heterozygous-butyrylcholinesterase-deficiency-in-a-patient-on-dialysis
#24
Naoki Tokunaga, Hisato Shima, Takuya Okamoto, Masato Maekawa, Jun Minakuchi
Serum levels of butyrylcholinesterase (BChE) are commonly used to assess liver function. Its levels have been reported to be significantly lower in patients undergoing dialysis. To the best of our knowledge, this is the first report of hereditary heterozygous BChE deficiency in a patient undergoing dialysis. Medical staff involved in the care of patients with BChE deficiency should be aware of anesthetic usage, because prolonged neuromuscular paralysis following the administration of succinylcholine or mivacurium may occur...
January 2024: Curēus
https://read.qxmd.com/read/38411028/chronic-glucocorticoid-management-in-neuromuscular-disease-a-survey-of-neuromuscular-neurologists
#25
JOURNAL ARTICLE
Lora Stepanian, Ruple S Laughlin, Corey Bacher, Aaron Izenberg, Victoria Hodgkinson, Adrienna Dyck, Ari Breiner, Charles D Kassardjian
INTRODUCTION/AIMS: Glucocorticoids (GC) are first-line therapy for many neuromuscular diseases. There is a lack of guidelines regarding the prevention and management of GC complications in the context of neuromuscular disease, introducing the potential for practice variation, that may compromise quality of care. Our aim was to evaluate the practice patterns among Canadian adult neuromuscular neurologists on the screening, management, and treatment of GC-related complications and to identify variances in practice...
February 27, 2024: Muscle & Nerve
https://read.qxmd.com/read/38410855/extravascular-injection-of-neuromuscular-blocking-drugs-a-systematic-review-of-current-evidence-and-management
#26
JOURNAL ARTICLE
Frederik Nietvelt, Imré Van Herreweghe, Vincent Godschalx, Filiep Soetens
Extravascular injection of neuromuscular blocking drugs (NMBDs) can cause a neuromuscular block because of systemic absorption. Currently, there are no guidelines available on managing extravasation of NMBDs. This article reviews the available literature on extravasation of NMBDs. Medline and Embase databases were searched for studies concerning the paravenous or subcutaneous injection of NMBDs. Nine articles were included consisting of seven case reports, one case series and one clinical trial. Rocuronium was used as primary NMBD in nine cases, vecuronium in two cases and pancuronium in one case...
February 26, 2024: European Journal of Anaesthesiology
https://read.qxmd.com/read/38406159/a-case-of-nemaline-myopathy-with-sleep-related-hypoventilation-diagnosed-using-polysomnography-during-daytime-napping
#27
Kanako Tamura, Kiyohide Komuta, Keijirou Yamauchi, Masashi Yokoyama, Hiroshi Morishita
This is the case of a 49-year-old woman who was admitted to the hospital for a close examination of pulmonary hypertension; however, the next morning, she developed carbon dioxide (CO2 ) narcosis and was started on artificial ventilation. As pulmonary arterial hypertension was ruled out, the patient was extubated, and 24-hour transcutaneous partial pressure of carbon dioxide (PCO2 )(transcutaneous carbon dioxide (TcPCO2 )) monitoring was performed to diagnose sleep-related hypoventilation. Polysomnography (PSG) during daytime napping revealed markedly decreased chest motion and a "pseudo-central event," which was neither central nor obstructive hypopnea...
January 2024: Curēus
https://read.qxmd.com/read/38400247/assessing-cognitive-workload-in-motor-decision-making-through-functional-connectivity-analysis-towards-early-detection-and-monitoring-of-neurodegenerative-diseases
#28
JOURNAL ARTICLE
Leonardo Ariel Cano, Ana Lía Albarracín, Alvaro Gabriel Pizá, Cecilia Elisabet García-Cena, Eduardo Fernández-Jover, Fernando Daniel Farfán
Neurodegenerative diseases (NDs), such as Alzheimer's, Parkinson's, amyotrophic lateral sclerosis, and frontotemporal dementia, among others, are increasingly prevalent in the global population. The clinical diagnosis of these NDs is based on the detection and characterization of motor and non-motor symptoms. However, when these diagnoses are made, the subjects are often in advanced stages where neuromuscular alterations are frequently irreversible. In this context, we propose a methodology to evaluate the cognitive workload (CWL) of motor tasks involving decision-making processes...
February 7, 2024: Sensors
https://read.qxmd.com/read/38398421/diabetes-mellitus-should-be-considered-while-analysing-sarcopenia-related-biomarkers
#29
REVIEW
Justyna Rentflejsz, Zyta Beata Wojszel
Sarcopenia is a chronic, progressive skeletal muscle disease characterised by low muscle strength and quantity or quality, leading to low physical performance. Patients with type 2 diabetes mellitus (T2DM) are more at risk of sarcopenia than euglycemic individuals. Because of several shared pathways between the two diseases, sarcopenia is also a risk factor for developing T2DM in older patients. Various biomarkers are under investigation as potentially valuable for sarcopenia diagnosis and treatment monitoring...
February 15, 2024: Journal of Clinical Medicine
https://read.qxmd.com/read/38395902/improving-management-of-ards-uniting-acute-management-and-long-term-recovery
#30
REVIEW
Nicola Latronico, M Eikermann, E W Ely, D M Needham
Acute Respiratory Distress Syndrome (ARDS) is an important global health issue with high in-hospital mortality. Importantly, the impact of ARDS extends beyond the acute phase, with increased mortality and disability for months to years after hospitalization. These findings underscore the importance of extended follow-up to assess and address the Post-Intensive Care Syndrome (PICS), characterized by persistent impairments in physical, cognitive, and/or mental health status that impair quality of life over the long-term...
February 23, 2024: Critical Care: the Official Journal of the Critical Care Forum
https://read.qxmd.com/read/38391731/calculated-maximal-volume-ventilation-cmvv-as-a-marker-of-early-respiratory-failure-in-amyotrophic-lateral-sclerosis-als
#31
JOURNAL ARTICLE
Umberto Manera, Maria Claudia Torrieri, Cristina Moglia, Antonio Canosa, Rosario Vasta, Francesca Palumbo, Enrico Matteoni, Sara Cabras, Maurizio Grassano, Alessandro Bombaci, Alessio Mattei, Michela Bellocchia, Giuseppe Tabbia, Fulvia Ribolla, Adriano Chiò, Andrea Calvo
Respiratory failure assessment is among the most debatable research topics in amyotrophic lateral sclerosis (ALS) clinical research due to the wide heterogeneity of its presentation. Among the different pulmonary function tests (PFTs), maximal voluntary ventilation (MVV) has shown potential utility as a diagnostic and monitoring marker, able to capture early respiratory modification in neuromuscular disorders. In the present study, we explored calculated MVV (cMVV) as a prognostic biomarker in a center-based, retrospective ALS population belonging to the Piemonte and Valle d'Aosta registry for ALS (PARALS)...
February 3, 2024: Brain Sciences
https://read.qxmd.com/read/38390901/anesthetic-recommendations-for-maternal-and-fetal-safety-in-nonobstetric-surgery-a-balancing-act
#32
JOURNAL ARTICLE
Leziga T Obiyo, Daniel Tobes, Naida M Cole
PURPOSE OF REVIEW: Nonobstetric surgery during pregnancy is associated with maternal and fetal risks. Several physiologic changes create unique challenges for anesthesiologists. This review highlights physiologic changes of pregnancy and presents clinical recommendations based on recent literature to guide anesthetic management for the pregnant patient undergoing nonobstetric surgery. RECENT FINDINGS: Nearly every anesthetic technique has been safely used in pregnant patients...
February 26, 2024: Current Opinion in Anaesthesiology
https://read.qxmd.com/read/38383128/atypical-organophosphate-poisoning-and-a-successful-case-of-prolonged-intubation-in-a-low-resource-newly-developed-intensive-care-unit-in-rural-zambia
#33
JOURNAL ARTICLE
Lara Bowell, Mark Timothy Williams
Organophosphate poisoning is a common, under-reported cause of attempted and completed suicide worldwide. Following the resolution of the acute cholinergic syndrome, patients may develop respiratory muscle and proximal limb weakness, known as intermediate syndrome. A young man was brought to our rural hospital unconscious, in extremis, due to organophosphate pesticide poisoning. He developed atypical intermediate syndrome with global paralysis, persistent fasciculations and prolonged cholinergic symptoms, differing from the recognised presentation...
February 21, 2024: BMJ Case Reports
https://read.qxmd.com/read/38380199/cardiac-arrest-in-the-post-anesthesia-care-unit-pacu-postoperative-recurrence-of-neuromuscular-block-after-sugammadex-reversal
#34
Vasyl Katerenchuk, Alexandre Calçada, Raquel Louzada, Daniela Rosinha, Ana C Batista, Andreia Capelão, Lisbete Cordeiro
Sugammadex has transformed clinical practice by enabling the rapid reversal of rocuronium-induced neuromuscular block (NMB) at any depth. We present a case of cardiac arrest following postoperative recurarization despite the sugammadex-induced transient reversal of NMB. Despite its proven clinical reliability, this case highlights the often overlooked aspects that must be considered when using this drug. An 84-year-old male patient was scheduled for a laparoscopic partial gastrectomy for gastric cancer...
January 2024: Curēus
https://read.qxmd.com/read/38373977/registrame-the-spanish-self-reported-patient-registry-of-spinal-muscular-atrophy
#35
JOURNAL ARTICLE
Maria Grazia Cattinari, Mencía de Lemus, Eduardo Tizzano
BACKGROUND: Spinal Muscular Atrophy (SMA) is a rare neuromuscular disorder characterized by progressive degeneration of motor neurons and muscle weakness resulting in premature death or severe motor disability. Over the last decade, SMA has dramatically changed thanks to new advances in care and the emergence of disease-specific treatments. RegistrAME is a self-reported specific disease registry with an accurate curation system. It has collected data on SMA patients in Spain since 2015, gathering demographic, clinical, and patient-reported outcome data, all of which are patient-relevant...
February 19, 2024: Orphanet Journal of Rare Diseases
https://read.qxmd.com/read/38371389/association-of-hematological-parameters-and-diabetic-neuropathy-a-retrospective-study
#36
JOURNAL ARTICLE
Aysha A AlShareef, Moafaq S Alrawaili, Salwa Awwadh Almutairi, Mustafa Mohammad Ayyad, Weam Alshora
BACKGROUND: Diabetic neuropathy (DN) is a common complication of type 2 diabetes (T2DM) and is characterized by persistent inflammation. Hematological parameters have emerged as a novel marker for detecting chronic inflammatory conditions, including diabetes. AIM: We aim to examine the association between HbA1c levels, which can indicate the presence of diabetic neuropathy, and hematological parameters to explore the possibility of using hematological parameters as a new indicator for DN in T2DM patients...
2024: Diabetes, Metabolic Syndrome and Obesity
https://read.qxmd.com/read/38371001/anesthetic-management-of-a-patient-with-central-core-disease-undergoing-thoracoscopic-lung-resection-the-importance-of-neuromuscular-monitoring-at-the-masseter-muscle
#37
Hiroko Baba, Ryo Wakabayashi, Hiroki Ichiyanagi, Aki Suzuki, Nobukazu Sato
Central core disease is a rare muscular disorder in which anesthetic considerations for the prevention of malignant hyperthermia and for avoidance of residual neuromuscular block are required. A 63-year-old woman with central core disease underwent thoracoscopic sublobar lung resection under total IV anesthesia with a prepared anesthetic workstation. The rocuronium-induced neuromuscular block was monitored by using acceleromyography at the left adductor pollicis muscle and the right masseter muscle. The recovery of neuromuscular block at the masseter was slower than that at the adductor pollicis...
January 2024: Curēus
https://read.qxmd.com/read/38370013/relationships-of-lower-extremity-and-trunk-asymmetries-in-elite-soccer-players
#38
JOURNAL ARTICLE
Tomas Maly, Mikulas Hank, Ferdia Fallon Verbruggen, Christian Clarup, Kirk Phillips, Frantisek Zahalka, Lucia Mala, Kevin R Ford
In light of previous research highlighting the prevalence of asymmetries in soccer players and possible links to injury risks, there is a crucial gap in the biomechanical understanding of complex relationships between lower extremity and trunk asymmetries in elite soccer players. The purpose of this study was to investigate the level, relationships, and differences among twelve different parameters of strength, morphological, and neuromuscular asymmetries in elite soccer players. Methods: Elite male soccer players ( n = 25, age 21...
2024: Frontiers in Physiology
https://read.qxmd.com/read/38365379/comparative-effectiveness-of-azathioprine-and-mycophenolate-mofetil-for-myasthenia-gravis-promise-mg-a-prospective-cohort-study
#39
JOURNAL ARTICLE
Pushpa Narayanaswami, Donald B Sanders, Laine Thomas, Dylan Thibault, Jason Blevins, Rishi Desai, Andrew Krueger, Kathie Bibeau, Bo Liu, Jeffrey T Guptill
BACKGROUND: Myasthenia gravis is an autoimmune disorder of the neuromuscular junction. Treatment typically includes symptomatic oral cholinesterase inhibitors, immunosuppression, and immunomodulation. In addition to corticosteroids, azathioprine and mycophenolate mofetil are the most frequently used immunosuppressants in North America. We aimed to evaluate the comparative effectiveness of these two drugs, and to assess the effect of the dose and duration of treatment. METHODS: We did a prospective cohort study at 19 academic centres in Canada and the USA...
March 2024: Lancet Neurology
https://read.qxmd.com/read/38364243/improving-neuromuscular-monitoring-through-education-based-interventions-and-studying-its-association-with-adverse-postoperative-outcomes-a-retrospective-observational-study
#40
JOURNAL ARTICLE
Shane G Carr, Jacob C Clifton, Robert E Freundlich, Leslie C Fowler, Edward R Sherwood, Matthew D McEvoy, Amy Robertson, Brent A Dunworth, Karen Y McCarthy, Matthew S Shotwell, Miklos D Kertai
BACKGROUND: We assessed the association between education-based interventions, the frequency of train-of-four (TOF) monitoring, and postoperative outcomes. METHODS: We studied adults undergoing noncardiac surgery from February 1, 2020 through October 31, 2021. Our education-based interventions consisted of 3 phases. An interrupted time-series analysis, adjusting for patient- and procedure-related characteristics and secular trends over time, was used to assess the associations between education-based interventions and the frequency of TOF monitoring, postoperative pulmonary complications (PPCs), 90-day mortality, and sugammadex dosage...
March 1, 2024: Anesthesia and Analgesia
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