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Neuromuscular monitoring

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https://www.readbyqxmd.com/read/29904285/sugammadex-appropriate-use-in-the-context-of-budgetary-constraints
#1
REVIEW
Guy Cammu
Purpose of Review: The purpose of this review is to assess how sugammadex impacts postoperative residual curarization using appropriate doses based on neuromuscular transmission monitoring and whether the advantages of sugammadex versus neostigmine outweigh its higher cost. Recent Findings: An accurate assessment of neuromuscular blockade with monitoring is necessary before selecting neostigmine versus sugammadex for reversal at the end of surgery to overcome incomplete neuromuscular recovery...
2018: Current Anesthesiology Reports
https://www.readbyqxmd.com/read/29865934/tele-monitoring-in-paediatric-and-young-home-ventilated-neuromuscular-patients-a-multicentre-case-control-trial
#2
Federica Trucco, Marina Pedemonte, Fabrizio Racca, Raffaele Falsaperla, Catia Romano, Anette Wenzel, Alessia D'Agostino, Angela Pistorio, Paola Tacchetti, Cristina Bella, Claudio Bruno, Carlo Minetti
Introduction Tele-monitoring (TM) has proved effective in the home management of adult ventilator-dependent neuromuscular disease (NMD) patients. We aimed to evaluate a 2-year longitudinal multicentre TM trial designed for young ventilated NMD patients in terms of feasibility, home management of exacerbations and caregivers' burden. Methods The TM trial protocol included patients' weekly scheduled overnight home-recording of SpO2 , heart rate and ventilation and their transmission to each TM centre the following morning...
January 1, 2018: Journal of Telemedicine and Telecare
https://www.readbyqxmd.com/read/29809090/muscle-activity-timing-and-head-kinematics-differ-between-male-and-female-ice-hockey-players-during-sudden-head-perturbations
#3
Chadwick Debison-Larabie, Bernadette A Murphy, Michael W R Holmes
This study examined sex differences in head kinematics and neck muscle activity during sudden head perturbations. Sixteen competitive ice hockey players participated. Three muscles were monitored bilaterally using surface electromyography: sternocleidomastoid (SCM), scalene (SCL) and splenius capitis (SPC). Head and thorax kinematics were measured. Head perturbations were induced by the release of a 1.5kg weight, attached to a wire wrapped around an adjustable pulley secured to the participant's head. Perturbations were delivered in 4 directions (flexion, extension, right and left lateral bend)...
May 29, 2018: Journal of Applied Biomechanics
https://www.readbyqxmd.com/read/29797592/scheduling-of-eccentric-lower-limb-injury-prevention-exercises-during-the-soccer-micro-cycle-which-day-of-the-week
#4
Ric Lovell, Matthew Whalan, Paul Wm Marshall, John A Sampson, Jason C Siegler, Martin Buchheit
Scheduling eccentric-based injury prevention programs (IPP) during the common 6-day micro-cycle in Soccer is challenged by recovery and tapering phases. This study profiled muscle damage, neuromuscular performance, and perceptual responses to a lower-limb eccentric-based IPP administered 1 (MD+1) versus 3 days (MD+3) post-match. 18 semi-professional players were monitored daily during 3 in-season 6-day micro-cycles, including weekly competitive fixtures. Capillary creatine kinase concentration (CK), posterior lower limb isometric peak force (PF), counter-movement jump (CMJ) performance, and muscle soreness were assessed 24 h prior to match-day (baseline), and every 24 h up to 120 h post-match...
May 24, 2018: Scandinavian Journal of Medicine & Science in Sports
https://www.readbyqxmd.com/read/29797194/erythrocyte-acetylcholinesterase-as-biomarker-of-pesticide-exposure-new-and-forgotten-insights
#5
Caio R D Assis, Amanda G Linhares, Mariana P Cabrera, Vagne M Oliveira, Kaline C C Silva, Marina Marcuschi, Elba V M Maciel Carvalho, Ranilson S Bezerra, Luiz B Carvalho
Acetylcholinesterase (AChE) acts on the hydrolysis of acetylcholine, rapidly removing this neurotransmitter at cholinergic synapses and neuromuscular junctions as well as in neuronal growth and differentiation, modulation of cell adhesion ("electrotactins") and aryl-acylamidase activity (AAA). This enzyme is also found in erythrocyte, as 160 kDa dimer that anchors to the plasma membrane via glycophosphatidylinositol. The function of this enzyme in erythrocytes has not yet been elucidated; however, it is suspected to participate in cell-to-cell interactions...
May 24, 2018: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/29794728/acute-noncardiogenic-pulmonary-edema-after-neostigmine-administration-during-the-recovery-period-of-general-anesthesia-a-case-report
#6
Wenjing Zhang, Cong Ning, Guoqing Zhao, Zhenbo Su
RATIONALE: Acute non-cardiogenic pulmonary edema (ANPE) is a rare but challenging complication which occurs during the perioperative period, mainly before and after the extubation in the course of the recovery period of general anesthesia. It is characterized by increased fluid in extravascular pulmonary spaces, preventing gas exchange and further resulting in respiratory failure. PATIENT CONCERNS: A 12-year-old boy who had undergone island skin flap in the right upper limb and who developed a unilateral pulmonary edema after the administration of neostigmine during the recovery period of general anesthesia...
May 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29791482/impact-of-high-versus-low-dose-neuromuscular-blocking-agent-administration-on-unplanned-30-day-readmission-rates-in-retroperitoneal-laparoscopic-surgery
#7
Martijn Boon, Chris Martini, H Keri Yang, Shuvayu S Sen, Rob Bevers, Michiel Warlé, Leon Aarts, Marieke Niesters, Albert Dahan
Recent data shows that a neuromuscular block (NMB) induced by administration of high doses of rocuronium improves surgical conditions in certain procedures. However, there are limited data on the effect such practices on postoperative outcomes. We performed a retrospective analysis to compare unplanned 30-day readmissions in patients that received high-dose versus low-dose rocuronium administration during general anesthesia for laparoscopic retroperitoneal surgery. This retrospective cohort study was performed in the Netherlands in an academic hospital where routine high-dose rocuronium NMB has been practiced since July 2015...
2018: PloS One
https://www.readbyqxmd.com/read/29790082/chronic-administration-of-pimozide-fails-to-attenuate-motor-and-pathological-deficits-in-two-mouse-models-of-amyotrophic-lateral-sclerosis
#8
Silvia Pozzi, Sai Sampath Thammisetty, Jean-Pierre Julien
Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease which presently does not have any efficient therapeutic approach. Pimozide, a Food and Drug Administration (FDA)-approved neuroepileptic drug, has been recently proposed as a promising treatment for ALS patients based on apparent stabilization of right hand muscles after a short-time administration. A new clinical trial started at the end of 2017 to recruit patients with a prolonged drug delivery schedule. Here, our aim was to investigate the effects of chronic administration of pimozide on disease progression and pathological events in two mouse models of ALS...
May 22, 2018: Neurotherapeutics: the Journal of the American Society for Experimental NeuroTherapeutics
https://www.readbyqxmd.com/read/29789948/the-application-of-neuromuscular-electrical-stimulation-nmes-in-cancer-rehabilitation-current-prescription-pitfalls-and-future-directions
#9
Dominic O'Connor, Brian Caulfield
The plethora of treatment complications associated with cancer can be offset by regular exercise participation; however, adherence to current guidelines is poor, in particular in those unable or not allowed to participate in voluntary exercise due to their underlying disease. Alternative therapies such as neuromuscular electrical stimulation (NMES) are promising although previous results in cancer survivors have been equivocal. This is likely in response to methodological issues such as inappropriate NMES prescription...
May 22, 2018: Supportive Care in Cancer: Official Journal of the Multinational Association of Supportive Care in Cancer
https://www.readbyqxmd.com/read/29788281/a-method-for-cranial-nerve-xi-silencing-during-surgery-of-the-foramen-magnum-region-technical-case-report
#10
Derek G Southwell, Jonathan D Breshears, William R Lyon, Michael W McDermott
BACKGROUND AND IMPORTANCE: Skull base surgery involves the microdissection and intraoperative monitoring of cranial nerves, including cranial nerve XI (CN XI). Manipulation of CN XI can evoke brisk trapezius contraction, which in turn may disturb the surgical procedure and risk patient safety. Here we describe a method for temporarily silencing CN XI via direct intraoperative application of 1% lidocaine. CLINICAL PRESENTATION: A 41-yr-old woman presented with symptoms of elevated intracranial pressure and obstructive hydrocephalus secondary to a hemangioblastoma of the right cerebellar tonsil...
May 18, 2018: Operative Neurosurgery (Hagerstown, Md.)
https://www.readbyqxmd.com/read/29782356/acute-neurologic-complications-during-extracorporeal-membrane-oxygenation-a-systematic-review
#11
Raoul Sutter, Kai Tisljar, Stephan Marsch
OBJECTIVES: We determine the frequency, risk factors, and mortality of neurologic complications in adults on extracorporeal membrane oxygenation and propose an algorithm for preventive strategies. DATA SOURCES: PubMed, Embase, and Cochrane databases. STUDY SELECTION: Screening was performed using predefined search terms to identify cohort studies reporting neurologic complications in adults during extracorporeal membrane oxygenation from 1990 to 2017...
May 18, 2018: Critical Care Medicine
https://www.readbyqxmd.com/read/29778398/antipsychotic-induced-disorders-reported-cases-and-prospective-study-on-muscle-biomarkers-after-high-exposure-to-haloperidol
#12
Abderrezak Khelfi, Mohammed Azzouz, Rania Abtroun, Mohammed Reggabi, Berkahoum Alamir
Antipsychotic drugs are known to induce neuromuscular effects. In this study, we review 13 years (2002-2014) of antipsychotic intoxications reported by the anti-poisoning center of Algiers (APCA). The most recorded symptoms were neuromuscular/muscular disorders, of which haloperidol was the most inducer among all antipsychotics. A prospective study was conducted between December 2012 and January 2017 to evaluate muscle effects generated after intentional or accidental ingestion of haloperidol. Fifty-one patients admitted in different emergency departments in Algiers were included in this study...
May 17, 2018: Toxicology and Applied Pharmacology
https://www.readbyqxmd.com/read/29777332/influence-of-tetanic-stimulation-on-the-staircase-phenomenon-and-the-acceleromyographic-time-course-of-neuromuscular-block-a-randomized-controlled-trial
#13
Guido Mazzinari, Carlos L Errando, Oscar Díaz-Cambronero, Manuel Martin-Flores
During neuromuscular monitoring, repeated electrical stimulation evokes muscle responses of increasing magnitude ('staircase phenomenon', SP). We aimed to evaluate whether SP affects time course and twitches' values of an acceleromyographic assessed neuromuscular block with or without previous tetanic stimulation. Fifty adult patients were randomized to receive a 50 Hz tetanic stimulus (S group) or not (C group) before monitor calibration. After 20 min of TOF ratio (TOFr) stimulation rocuronium was administered...
May 18, 2018: Journal of Clinical Monitoring and Computing
https://www.readbyqxmd.com/read/29759488/neuromuscular-disorders-and-the-role-of-the-clinical-electrophysiologist
#14
REVIEW
Haisam Ismail, Elizabeth Raynor, Peter Zimetbaum
Cardiac involvement is common and may be the presenting or predominant manifestation in a variety of neuromuscular disorders, most notably the inherited muscle disorders, or muscular dystrophies. Cardiac manifestations of the neuromuscular disorders result from pathological involvement of the myocardium and the cardiac conduction system, with resulting cardiomyopathy or rhythm disturbances including supraventricular arrhythmias, life-threatening ventricular arrhythmias, and sudden cardiac death. Many of these neuromuscular disorders are rare and may be unrecognized by even experienced specialists in internal and cardiovascular medicine...
October 2017: JACC. Clinical Electrophysiology
https://www.readbyqxmd.com/read/29756064/neuromuscular-monitoring-an-update
#15
REVIEW
Mădălina Duţu, Robert Ivaşcu, Oana Tudorache, Darius Morlova, Alina Stanca, Silvius Negoiţă, Dan Corneci
This review makes an advocacy for neuromuscular blockade monitoring during anaesthesia care, by: (i) describing the fundamental principles of the methods currently available, at the same time emphasizing quantitative recording measurements; (ii) describing the different ways in which muscles respond to the effect of neuromuscular blockade and their use in clinical practice; (iii) presenting results of different studies on timing and agents of neuromuscular block reversal, including a recommendation for sugammadex use and experimental results with calabadion and (iv) in the end emphasizing the need for implementing neuromuscular monitoring as a practice that should be used every time a neuromuscular block is required...
April 2018: Romanian Journal of Anaesthesia and Intensive Care
https://www.readbyqxmd.com/read/29742747/improving-the-signal-to-noise-ratio-when-monitoring-countermovement-jump-performance
#16
Rodney A Kennedy, David Drake
Kennedy, RA and Drake, D. Improving the signal-to-noise ratio when monitoring countermovement jump performance. J Strength Cond Res XX(X): 000-000, 2018-Countermovement jump (CMJ) performance has been routinely used to monitor neuromuscular status. However, the protocol used to establish the criterion score is not well documented. The purpose of this study was to examine how the protocol used would influence of the sensitivity of CMJ variables in rugby union players. Fifteen male (age: 19.7 ± 0.5 years) rugby union players performed 8 CMJs on 2 occasions, separated by 7 days...
May 8, 2018: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/29722285/optimal-neuromuscular-blocking-effects-of-remifentanil-during-tracheal-intubation-under-general-anesthesia
#17
So Young Kwon, Si Wook Chung, Jin Deok Joo
Objective This study was performed to determine the effect of the remifentanil dose on the onset time of rocuronium with electromyography. Methods This retrospective comparative study included 75 patients undergoing general anesthesia for elective surgery. Patients received lidocaine (40 mg) and propofol (2 mg/kg) followed by rocuronium (0.6 mg/kg) with either saline infusion (Group S), remifentanil at 0.5 µg/kg/minute (Group R 0.5), or remifentanil at 1.0 µg/kg/minute (Group R 1.0). Neuromuscular block was monitored by train-of-four (TOF) electromyography, and the times taken to reach TOF 0 and TOF ratio (TOFR) 25% were recorded...
January 1, 2018: Journal of International Medical Research
https://www.readbyqxmd.com/read/29713767/monitoring-skeletal-muscle-chronic-fatty-degenerations-with-fast-t1-mapping
#18
Benjamin Marty, Bertrand Coppa, Pierre G Carlier
OBJECTIVES: To develop a fast, high-resolution T1-mapping sequence dedicated to skeletal muscle imaging, and to evaluate the potential of T1 as a robust and sensitive biomarker for the monitoring of chronic fatty degenerations in a dystrophic disease. METHODS: The magnetic resonance imaging sequence consisted of the acquisition of a 1,000-radial-spokes FLASH echo-train following magnetisation inversion, resulting in 10s scan time per slice. Temporal image series were reconstructed using compressed sensing and T1 maps were computed using Bloch simulations...
April 30, 2018: European Radiology
https://www.readbyqxmd.com/read/29705688/survey-of-how-different-groups-of-veterinarians-manage-the-use-of-neuromuscular-blocking-agents-in-anesthetized-dogs
#19
Manuel Martin-Flores, Daniel M Sakai, Luis Campoy, Robin D Gleed
OBJECTIVE: To analyze practice habits associated with the use, reversal and monitoring of nondepolarizing neuromuscular blocking agents (NMBAs) in dogs by different groups of veterinarians. STUDY DESIGN: Online anonymous survey to veterinarians. POPULATION: Data from 390 answered surveys. METHODS: A questionnaire was sent to e-mail list servers of the American College of Veterinary Anesthesia and Analgesia (ACVAA-list), Sociedad Española de Anestesia y Analgesia Veterinaria (SEEAV-list), Colégio Brasileiro de Anestesiologia Veterinária (Brazilian College of Veterinary Anesthesiology; CBAV-list) and American College of Veterinary Ophthalmologists (ACVO-list) to elicit information regarding use of NMBAs and reversal agents, monitoring techniques, criteria for redosing, reversing and assessing adequacy of recovery of neuromuscular function...
March 23, 2018: Veterinary Anaesthesia and Analgesia
https://www.readbyqxmd.com/read/29704921/assistive-technologies-to-overcome-sarcopenia-in-ageing
#20
REVIEW
Rachel A Scott, Michele L Callisaya, Gustavo Duque, Peter R Ebeling, David Scott
Sarcopenia is an age-related decline in skeletal muscle mass and function that results in disability and loss of independence. It affects up to 30% of older adults. Exercise (particularly progressive resistance training) and nutrition are key strategies in preventing and reversing declines in muscle mass, strength and power during ageing, but many sarcopenic older adults fail to meet recommended levels of both physical activity and dietary nutrient intake. Assistive technology (AT) describes devices or systems used to maintain or improve physical functioning...
June 2018: Maturitas
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