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https://www.readbyqxmd.com/read/29304956/editorial-commentary-superior-capsule-reconstruction-with-dermal-allograft-effective-marketing-or-the-real-deal
#1
EDITORIAL
Timothy S Leroux
The young patient with a massive, irreparable rotator cuff tear is a challenging problem. Not only is this patient population demanding, but of the few surgical options that exist to manage this problem, each have their own unique limitations; as such, the orthopaedic community continues to search for a treatment that maximizes outcome and durability, while minimizing risk and preserving the native shoulder. Over the past few years, there has been considerable interest in a new surgical technique: the superior capsule reconstruction (SCR)...
January 2018: Arthroscopy: the Journal of Arthroscopic & related Surgery
https://www.readbyqxmd.com/read/29234940/st-gallen-consensus-on-safe-implementation-of-transanal-total-mesorectal-excision
#2
Michel Adamina, Nicolas C Buchs, Marta Penna, Roel Hompes
BACKGROUND: The management of rectal cancer has evolved over the years, including the recent rise of Transanal Total Mesorectal Excision (TaTME). TaTME addresses the limitations created by the bony confines of the pelvis, bulky tumours, and fatty mesorectum, particularly for low rectal cancers. However, guidance is required to ensure safe implementation and to avoid the pitfalls and potential major morbidity encountered by the early adopters of TaTME. We report a broad international consensus statement, which provides a basis for optimal clinical practice...
December 12, 2017: Surgical Endoscopy
https://www.readbyqxmd.com/read/29232466/real-world-evidence-in-the-treatment-of-ovarian-cancer
#3
E A Eisenhauer
Introduction: 'Real-world evidence (RWE)' refers to information on the utilization and outcome of new therapies and technologies in clinical practice. RWE may include single institution cohort studies, population-based health services studies, or (inter)national data on survival and mortality. This paper reviews RWE on the impact of treatment in ovarian cancer. Materials and methods: A literature review of publications addressing population level survival outcomes of new surgical and systemic treatment interventions in ovarian cancer was undertaken...
November 1, 2017: Annals of Oncology: Official Journal of the European Society for Medical Oncology
https://www.readbyqxmd.com/read/29198352/editorial-commentary-the-wake-of-the-dragon-will-the-orthopaedic-community-adopt-the-shoulder-arthroscopic-latarjet-procedure-as-we-adopted-the-arthroscopic-rotator-cuff-repair
#4
EDITORIAL
Pascal Boileau, David Saliken
The Latarjet procedure is a complex and difficult operation when performed both with an open approach and arthroscopically. The difficulties come from the fact that it is a combined intra- and extra-articular procedure, and that working close to the brachial plexus may be frightening for surgeons. Because of the high complication and reoperation rates reported in the literature, this procedure is, at the moment, rejected by a large part of the orthopaedic community, specifically in North America. The Chinese experience shows, after the European one, that arthroscopic Latarjet is an efficient and irreplaceable option for the treatment of recurrent anterior shoulder instability in the context of capsular and/or glenoid deficiency...
December 2017: Arthroscopy: the Journal of Arthroscopic & related Surgery
https://www.readbyqxmd.com/read/29173655/management-of-well-differentiated-gastroenteropancreatic-neuroendocrine-tumors-gepnets-a-review
#5
REVIEW
Gurleen Pasricha, Parikshit Padhi, Nour Daboul, Dulabh K Monga
PURPOSE: Neuroendocrine tumors (NETs) are heterogeneous tumors that arise from the neuroendocrine cells of the digestive tract and other organs, such as the lung, ovary, and thyroid glands. They can be well differentiated or poorly differentiated, and management of these tumors differs for each histologic subtype. We have performed a review of NETs and focused on management of well-differentiated gastroenteropancreatic neuroendocrine tumors (GEPNETs) and carcinoid syndrome. METHODS: A PubMed search was performed to obtain articles on the management of well-differentiated NETs...
November 2017: Clinical Therapeutics
https://www.readbyqxmd.com/read/29164008/spontaneous-endometriosis-within-a-primary-umbilical-hernia
#6
Nicole R Laferriere, Christopher G Yheulon
Umbilical hernias are rather common in the General Surgery clinic; however, endometriosis of an umbilical hernia is rare. It is especially unusual to have endometriosis of an umbilical hernia spontaneously occur compared to occurring at a site of a prior surgery. We present a case of spontaneous endometriosis of an umbilical hernia without prior surgery to her umbilicus. She had not presented with the usual symptoms of endometriosis and it was not considered as a diagnosis prior to surgery. Umbilical endometriosis is rare but usually occurs after prior laparoscopic surgery...
November 2017: Hawai'i Journal of Medicine & Public Health: a Journal of Asia Pacific Medicine & Public Health
https://www.readbyqxmd.com/read/29070964/trigeminal-neuralgia-commonly-precedes-the-diagnosis-of-multiple-sclerosis
#7
Ahmad Fallata, Amber Salter, Tuula Tyry, Gary R Cutter, Ruth Ann Marrie
BACKGROUND: Trigeminal neuralgia (TN) is a well-recognized cause of facial pain in the general population, and multiple sclerosis (MS) accounts for some of these cases. However, the prevalence of TN in MS is poorly understood. We investigated the prevalence of TN and how often TN is the initial presentation of MS in a large MS cohort. METHODS: In 2009, we surveyed participants in the North America Research Committee on Multiple Sclerosis Registry regarding TN, including date of onset and pharmacologic and nonpharmacologic treatments used...
September 2017: International Journal of MS Care
https://www.readbyqxmd.com/read/28953706/post-operative-resolution-of-mri-signal-intensity-changes-and-the-associated-impact-on-outcomes-in-degenerative-cervical-myelopathy-analysis-of-a-global-cohort-of-patients
#8
So Kato, Aria Nouri, Hamed Reihani-Kermani, Yasushi Oshima, Joseph Cheng, Michael G Fehlings
STUDY DESIGN: Sub-analysis of the prospective AOSpine CSM North America and International studies. OBJECTIVE: To describe the post-operative changes in MRI spinal cord signal intensity in degenerative cervical myelopathy (DCM) patients and to investigate the impact of its post-operative resolution on clinical outcomes. SUMMARY OF BACKGROUND DATA: When examining the spinal cord, hyperintensity found in MRI T2-weighted images and hypointensity in T1-weighted images are known to correlate with pre-operative severity of DCM and to predict post-operative neurological recovery...
September 26, 2017: Spine
https://www.readbyqxmd.com/read/28945692/the-surgical-management-of-tibial-spine-fractures-in-children-a-survey-of-the-pediatric-orthopaedic-society-of-north-america-posna
#9
Taylor J Jackson, Eileen P Storey, Theodore J Ganley
BACKGROUND: Tibial spine fractures are rare, complex injuries. Management remains varied given a lack of consensus about the optimal approach. Thus, the purpose of this study is to determine prevailing strategies among pediatric orthopaedists and establish areas of agreement and ongoing controversy in the management of tibial spine fractures. METHODS: An electronic survey was distributed to the Pediatric Orthopaedic Society of North America (POSNA) membership. Surgeon demographics, experience, and responses to clinical vignettes were collected...
September 22, 2017: Journal of Pediatric Orthopedics
https://www.readbyqxmd.com/read/28932565/unique-distribution-of-programmed-death-ligand-1-pd-l1-expression-in-east-asian-non-small-cell-lung-cancer
#10
Yunjian Pan, Difan Zheng, Yuan Li, Xu Cai, Zongli Zheng, Yan Jin, Haichuan Hu, Chao Cheng, Lei Shen, Jian Wang, Hongbin Ji, Yihua Sun, Xiaoyan Zhou, Haiquan Chen
BACKGROUND: To determine the proportion and clinical features of programmed death ligand 1 (PD-L1) expression in East Asian non-small cell lung cancer (NSCLC). METHODS: PD-L1 expression was assessed by immunohistochemistry (IHC) and tumor proportion score (TPS) with the use of PD-L1 IHC 22C3 antibody (Dako North America) in 108 surgically resected lung squamous cell carcinomas (SCC) and 221 lung adenocarcinomas (LUADs), and was correlated with clinical variables, histologic subtypes, and common driver mutations...
August 2017: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/28916847/endoscopic-resection-of-gastric-gastrointestinal-stromal-tumors-originating-from-the-muscularis-propria-layer-in-north-america-methods-and-feasibility-data
#11
Iman Andalib, Daniel Yeoun, Ramesh Reddy, Steve Xie, Shahzad Iqbal
INTRODUCTION: Gastrointestinal stromal tumors (GISTs) are the most common mesenchymal tumors of the gastrointestinal tract. In recent years, endoscopic procedures such as endoscopic enucleation (EN) and endoscopic full-thickness resection (EFTR) have been used to resect GISTs. This study aimed to investigate the clinical efficacy, safety, and feasibility of endoscopic resection of GISTs in a North American population. METHODS: A total of 25 patients with gastric submucosal lesions (SML) underwent endoscopic resection from December 2014 to April 2016...
September 15, 2017: Surgical Endoscopy
https://www.readbyqxmd.com/read/28888674/geographical-variations-in-clinical-presentation-and-outcomes-of-decompressive-surgery-in-patients-with-symptomatic-degenerative-cervical-myelopathy-analysis-of-a-prospective-international-multicenter-cohort-study-of-757-patients
#12
Michael G Fehlings, Branko Kopjar, Ahmed Ibrahim, Lindsay A Tetreault, Paul M Arnold, Helton Defino, Shashank Sharad Kale, S Tim Yoon, Giuseppe M Barbagallo, Ronald H M Bartels, Qiang Zhou, Alexander R Vaccaro, Mehmet Zileli, Gamaliel Tan, Yasutsugu Yukawa, Darrel S Brodke, Christopher I Shaffrey, Osmar Santos de Moraes, Eric J Woodard, Massimo Scerrati, Masato Tanaka, Tomoaki Toyone, Rick C Sasso, Michael E Janssen, Ziya L Gokaslan, Manuel Alvarado, Ciaran Bolger, Christopher M Bono, Mark B Dekutoski
BACKGROUND CONTEXT: Degenerative cervical myelopathy (DCM) is a progressive degenerative spine disease and the most common cause of spinal cord impairment in adults worldwide. There is a paucity of studies reporting on regional variations in demographics, clinical presentation, disease causation and surgical effectiveness. PURPOSE: To evaluate differences in demographics, causative pathology, management strategies, surgical outcomes, length of hospital stay and complications across four geographic regions...
September 6, 2017: Spine Journal: Official Journal of the North American Spine Society
https://www.readbyqxmd.com/read/28864790/a-survey-of-dental-implant-instruction-in-predoctoral-dental-curricula-in-north-america
#13
Hidemichi Kihara, Jie Sun, Maiko Sakai, Shigemi Nagai, John Da Silva
The aim of this study was to investigate the extent and forms of predoctoral implant dentistry instruction in North American dental schools and to identify future directions and challenges. The survey collected data on curriculum content, departmental oversight, techniques, and materials, as well as current problems to be solved. The 30-question survey was sent in 2012 to the dean or administrator in charge of the predoctoral curriculum of all 73 dental schools in the U.S. and Canada at the time; four reminders were sent...
September 2017: Journal of Dental Education
https://www.readbyqxmd.com/read/28862111/how-can-we-improve-education-of-breast-surgeons-across-europe
#14
Agnieszka Kolacinska
The proposed global curriculum developed by the American Society of Surgical Oncology (SSO) and the European Society of Surgical Oncology (ESSO) and the textbook: provides a state-of- the- art of breast cancer surgery, complements the syllabus and curriculum of the Union Europeenne des Medecins Specialistes (UEMS) examination in breast surgery/ European Board of Surgery Qualification in Breast Surgery (EBSQinBS) administered by ESSO (1) Knowledge and understanding of the principles of breast cancer incidence, aetiology, risk factors, genetics, premalignant and high-risk lesions, pathology, prognostic and predictive factors, risk prediction models, screening, diagnosis and imaging, breast cancer, oncoplastic, reconstructive breast surgery, axillary surgery and future perspective for this, radiation therapy, neoadjuvant and adjuvant systemic treatment- endocrine-, immuno- and chemotherapy, side effects and toxicities of treatment, locoregional recurrence, follow-up, locally advanced breast cancer, metastatic breast cancer, breast cancer in young and elderly patients, survivor issues, lymphedema, palliative care, chroni pain, body image and sexuality, fertility issues, cognitive functions, etc...
July 2017: Chirurgia
https://www.readbyqxmd.com/read/28861195/india-based-knee-osteoarthritis-evaluation-ikare-a-multi-centre-cross-sectional-study-on-the-management-of-knee-pain-and-early-osteoarthritis-in-india
#15
Parag Sancheti, Vijay D Shetty, Mandeep S Dhillon, Sheila A Sprague, Mohit Bhandari
BACKGROUND: Access to early knee osteoarthritis treatment in low and middle income nations is often believed to be limited. We conducted a cross-sectional study in India to assess prior access to treatment among patients presenting with knee pain to specialist orthopaedic clinics. METHODS: The multi-centre, cross-sectional study included patients presenting with knee pain at 3 hospitals in India. Patients who met the inclusion criteria and provided informed consent completed a questionnaire designed to assess patient demographics, socioeconomic status, knee pain, treatment method, and patient's knowledge on osteoarthritis (OA)...
September 2017: Clinics in Orthopedic Surgery
https://www.readbyqxmd.com/read/28836063/prognostic-significance-of-fuhrman-grade-and-age-for-cancer-specific-and-overall-survival-in-patients-with-papillary-renal-cell-carcinoma-results-of-an-international-multi-institutional-study-on-2189-patients
#16
H Borgmann, M Musquera, A Haferkamp, A Vilaseca, T Klatte, S F Shariat, A Scavuzzo, M A Jimenez Rios, I Wolff, U Capitanio, P Dell'Oglio, L M Krabbe, E Herrmann, T Ecke, D Vergho, N Huck, N Wagener, S Pahernik, S Zastrow, M Wirth, C Surcel, C Mirvald, K Prochazkova, G Hutterer, R Zigeuner, L Cindolo, M Hora, C G Stief, M May, S D Brookman-May
PURPOSE: Because the prognostic impact of the clinical and pathological features on cancer-specific survival (CSS) and overall survival (OS) in patients with papillary renal cell carcinoma (papRCC) is still controversial, we want to assess the impact of clinicopathological features, including Fuhrman grade and age, on survival in surgically treated papRCC patients in a large multi-institutional series. METHODS: We established a comprehensive multi-institutional database of surgically treated papRCC patients...
December 2017: World Journal of Urology
https://www.readbyqxmd.com/read/28826742/a-comprehensive-review-and-update-on-crohn-s-disease
#17
Mahesh Gajendran, Priyadarshini Loganathan, Anthony P Catinella, Jana G Hashash
The term inflammatory bowel disease (IBD) refers principally to two major categories of chronic relapsing inflammatory intestinal disorders: Crohn's disease (CD) and ulcerative colitis (UC). In the United States, it is currently estimated that about 1.5 million people suffer from IBD, causing considerable suffering, mortality and economic loss every year. Yet the cause of IBD is unknown, and until we understand more, prevention or cure will not be possible. There is a lot of variation in the incidence and prevalence of CD based on geographic region, environment, immigrant population, and ethnic groups...
August 18, 2017: Disease-a-month: DM
https://www.readbyqxmd.com/read/28814237/statins-in-aortic-stenosis
#18
Karl Norrington, Emmanuel Androulakis, Evangelos Oikonomou, Georgia Vogiatzi, Dimitris Tousoulis
Calcific aortic stenosis (AS) is the most common form of valvular heart disease in Europe and North America. It is a progressive disease with a prolonged period of asymptomatic latency which eventually leads to critical left ventricular outflow tract obstruction necessitating surgical replacement of the valve. Statins are lipid-lowering drugs with a robust evidence base demonstrating clinical benefit in atherosclerotic coronary artery disease. There has therefore been significant interest in the potential benefit of statins in AS...
August 15, 2017: Current Pharmaceutical Design
https://www.readbyqxmd.com/read/28809631/-comparison-between-the-range-of-movement-canine-real-cervical-spine-and-numerical-simulation-computer-model-validation
#19
R Srnec, Z Horák, R Sedláček, M Sedlinská, M Krbec, A Nečas
PURPOSE OF THE STUDY In developing new or modifying the existing surgical treatment methods of spine conditions an integral part of ex vivo experiments is the assessment of mechanical, kinematic and dynamic properties of created constructions. The aim of the study is to create an appropriately validated numerical model of canine cervical spine in order to obtain a tool for basic research to be applied in cervical spine surgeries. For this purpose, canine is a suitable model due to the occurrence of similar cervical spine conditions in some breeds of dogs and in humans...
2017: Acta Chirurgiae Orthopaedicae et Traumatologiae Cechoslovaca
https://www.readbyqxmd.com/read/28767806/extracranial-carotid-stenosis-evidence-based-review
#20
Carolina Dutra Queiroz Flumignan, Ronald Luiz Gomes Flumignan, Túlio Pinho Navarro
Extracranial cerebrovascular disease is one of the most important causes of death and disability worldwide and its treatment is based on clinical and surgical strategies, the latter being performed by conventional or endovascular techniques. The management of stenosis of the carotid bifurcation is mainly aimed at preventing stroke and has been the subject of extensive investigation. The role of clinical treatment has been re-emphasized, but carotid endarterectomy remains the first-line treatment for symptomatic patients with 50% to 99% stenosis and for asymptomatic patients with 60% to 99% stenosis...
May 2017: Revista do Colégio Brasileiro de Cirurgiões
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