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https://www.readbyqxmd.com/read/28814237/statins-in-aortic-stenosis
#1
Karl Norrington, Emmanuel Androulakis, Evangelos Oikonomou, Georgia Vogiatzi, Dimitris Tousoulis
Calcific aortic stenosis (AS) is the most common form of valvular heart disease in Europe and North America. It is a progressive disease with a prolonged period of asymptomatic latency which eventually leads to critical left ventricular outflow tract obstruction necessitating surgical replacement of the valve. Statins are lipid-lowering drugs with a robust evidence base demonstrating clinical benefit in atherosclerotic coronary artery disease. There has therefore been significant interest in the potential benefit of statins in AS...
August 15, 2017: Current Pharmaceutical Design
https://www.readbyqxmd.com/read/28809631/-comparison-between-the-range-of-movement-canine-real-cervical-spine-and-numerical-simulation-computer-model-validation
#2
R Srnec, Z Horák, R Sedláček, M Sedlinská, M Krbec, A Nečas
PURPOSE OF THE STUDY In developing new or modifying the existing surgical treatment methods of spine conditions an integral part of ex vivo experiments is the assessment of mechanical, kinematic and dynamic properties of created constructions. The aim of the study is to create an appropriately validated numerical model of canine cervical spine in order to obtain a tool for basic research to be applied in cervical spine surgeries. For this purpose, canine is a suitable model due to the occurrence of similar cervical spine conditions in some breeds of dogs and in humans...
2017: Acta Chirurgiae Orthopaedicae et Traumatologiae Cechoslovaca
https://www.readbyqxmd.com/read/28767806/extracranial-carotid-stenosis-evidence-based-review
#3
Carolina Dutra Queiroz Flumignan, Ronald Luiz Gomes Flumignan, Túlio Pinho Navarro
Extracranial cerebrovascular disease is one of the most important causes of death and disability worldwide and its treatment is based on clinical and surgical strategies, the latter being performed by conventional or endovascular techniques. The management of stenosis of the carotid bifurcation is mainly aimed at preventing stroke and has been the subject of extensive investigation. The role of clinical treatment has been re-emphasized, but carotid endarterectomy remains the first-line treatment for symptomatic patients with 50% to 99% stenosis and for asymptomatic patients with 60% to 99% stenosis...
May 2017: Revista do Colégio Brasileiro de Cirurgiões
https://www.readbyqxmd.com/read/28760477/the-society-of-thoracic-surgeons-congenital%C3%A2-heart-surgery-database-2017-update-on-research
#4
Marshall L Jacobs, Jeffrey P Jacobs, Kevin D Hill, Christoph Hornik, Sean M O'Brien, Sara K Pasquali, David Vener, S Ram Kumar, Robert H Habib, David M Shahian, Fred H Edwards, Felix G Fernandez
The Society of Thoracic Surgeons Congenital Heart Surgery Database (STS CHSD) is the largest congenital and pediatric cardiac surgical clinical data registry in the world. It contains data pertaining to more than 435,000 total operations. The most recent biannual feedback report to participants (Spring 2017, Report of the Twenty-Sixth Harvest) included analysis of data submitted from 127 hospitals in North America. That represents nearly all centers performing pediatric and congenital heart operations in the United States and Canada...
July 28, 2017: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/28698181/risk-factors-for-surgical-site-infection-following-cesarean-delivery-a-retrospective-cohort-study
#5
Felicia Ketcheson, Christy Woolcott, Victoria Allen, Joanne M Langley
BACKGROUND: The rate of cesarean delivery is increasing in North America. Surgical site infection following this operation can make it difficult to recover, care for a baby and return home. We aimed to determine the incidence of surgical site infection to 30 days following cesarean delivery, associated risk factors and whether risk factors differed for predischarge versus postdischarge infection. METHODS: We identified a retrospective cohort in Nova Scotia by linking the provincial perinatal database to hospital admissions and physician billings databases to follow women for 30 days after they had given birth by cesarean delivery between Jan...
July 11, 2017: CMAJ Open
https://www.readbyqxmd.com/read/28678119/risk-factors-for-and-clinical-outcomes-of-dysphagia-after-anterior-cervical-surgery-for-degenerative-cervical-myelopathy-results-from-the-aospine-international-and-north-america-studies
#6
Narihito Nagoshi, Lindsay Tetreault, Hiroaki Nakashima, Paul M Arnold, Giuseppe Barbagallo, Branko Kopjar, Michael G Fehlings
BACKGROUND: Although dysphagia is a common complication after anterior cervical decompression and fusion, important risk factors have not been rigorously evaluated. Furthermore, the impact of dysphagia on neurological and quality-of-life outcomes is not fully understood. The aim of this study was to determine the prevalence of and risk factors for dysphagia, and the impact of this complication on short and long-term clinical outcomes, in patients treated with anterior cervical decompression and fusion...
July 5, 2017: Journal of Bone and Joint Surgery. American Volume
https://www.readbyqxmd.com/read/28677422/evaluation-of-a-standardized-perioperative-management-protocol-in-the-adult-hematology-anticoagulation-management-service
#7
Diane J Lum, Patricia A Ross, Martin A Bishop, Michelle L Caetano, Michael B Streiff
BACKGROUND: In North America, 250,000 patients on vitamin K antagonists require surgical procedures each year. Temporary interruption of oral anticoagulation and perioperative bridging therapy with unfractionated heparin or low-molecular-weight heparin are recommended by the American College of Chest Physicians 2012 for select patients. OBJECTIVES: The study objectives are to evaluate adherence and nonadherence to the Johns Hopkins clinic guidelines for perioperative management of anticoagulation and identify bleeding or thromboembolic events during perioperative management of anticoagulation...
July 1, 2017: Annals of Pharmacotherapy
https://www.readbyqxmd.com/read/28658439/perioperative-management-of-drugs-commonly-used-in-patients-with-rheumatic-diseases-a-review
#8
André Silva Franco, Leandro Ryuchi Iuamoto, Rosa Maria Rodrigues Pereira
Rheumatic diseases are very prevalent, affecting about 7 million people in North America; they affect the musculoskeletal system, often with systemic involvement and potential for serious consequences and limitation on quality of life. Clinical treatment is usually long-term and includes drugs that are considered either simple or complex and are occasionally unknown to many health professionals who do not know how to manage these patients in emergency units and surgical wards. Thus, it is important for clinicians, surgeons and anesthesiologists who are involved with rheumatic patients undergoing surgery to know the basic principles of therapy and perioperative management...
June 2017: Clinics
https://www.readbyqxmd.com/read/28571679/side-to-side-refluxing-nondismembered-ureterocystotomy-a-novel-strategy-to-address-obstructed-megaureters-in-children
#9
Fahad A Alyami, Martin A Koyle, Paul R Bowlin, Joseph M Gleason, Luis H Braga, Armando J Lorenzo
PURPOSE: A nonrefluxing megaureter is a relatively common cause of antenatal hydronephrosis. Although nonoperative management is favored, surgical intervention is sometimes warranted. However, there is controversy regarding the best approach, particularly in young children. We describe our experience with nondismembered side-to-side refluxing ureterocystotomy as a simple option to address obstruction. MATERIALS AND METHODS: Between January 2012 and January 2017, 32 patients underwent ureterocystotomy at 4 referral centers in North America...
May 29, 2017: Journal of Urology
https://www.readbyqxmd.com/read/28551190/clinical-trial-of-local-anesthetic-protocols-for-acute-pain-associated-with-caustic-paste-disbudding-in-dairy-calves
#10
Charlotte B Winder, Stephen J LeBlanc, Derek B Haley, Kerry D Lissemore, M Ann Godkin, Todd F Duffield
Caustic paste disbudding is becoming more commonplace in North America. A large body of work has examined pain control for cautery disbudding and surgical dehorning, but fewer studies have evaluated pain control for caustic paste disbudding, and results conflict regarding benefits of local anesthesia. In humans, the pain associated with a caustic, chemical burn can differ in nature, duration, and intensity compared with a thermal burn. The objective of this clinical trial was to evaluate the effects of either a lidocaine cornual nerve block or a topical anesthetic incorporated into caustic paste on the acute pain of caustic paste disbudding...
May 24, 2017: Journal of Dairy Science
https://www.readbyqxmd.com/read/28523381/national-clinical-guidelines-for-non-surgical-treatment-of-patients-with-recent-onset-neck-pain-or-cervical-radiculopathy
#11
REVIEW
Per Kjaer, Alice Kongsted, Jan Hartvigsen, Alexander Isenberg-Jørgensen, Berit Schiøttz-Christensen, Bolette Søborg, Charlotte Krog, Christian Martin Møller, Christine Marie Bækø Halling, Henrik Hein Lauridsen, Inge Ris Hansen, Jesper Nørregaard, Karsten Juhl Jørgensen, Lars Valentin Hansen, Marie Jakobsen, Martin Bach Jensen, Martin Melbye, Peter Duel, Steffan W Christensen, Tina Myung Povlsen
PURPOSE: To summarise recommendations about 21 selected non-surgical interventions for recent onset (<12 weeks) non-specific neck pain (NP) and cervical radiculopathy (CR) based on two guidelines from the Danish Health Authority. METHODS: Two multidisciplinary working groups formulated recommendations based on the GRADE approach. RESULTS: Twelve recommendations were based on evidence and nine on consensus. Management should include information about prognosis, warning signs, and advise to remain active...
May 18, 2017: European Spine Journal
https://www.readbyqxmd.com/read/28520718/retrospective-observational-evaluation-of-postoperative-oxygen-saturation-levels-and-associated-postoperative-respiratory-complications-and-hospital-resource-utilization
#12
Satya Krishna Ramachandran, Aleda Thompson, Jaideep J Pandit, Scott Devine, Amy M Shanks
INTRODUCTION: The clinical importance of postoperative episodic hypoxemia is still unclear, and therefore largely under-studied. As a result, there is limited understanding of its relationship with early postoperative respiratory complications (PRC, defined as intubation within three days of surgery) and hospital resource utilization. MATERIALS AND METHODS: This single center study was performed using a retrospective observational design. We described population based definitions of desaturation from continuous SpO2 monitoring data captured in the post anesthesia care unit (PACU), namely median SpO2 in PACU, duration of desaturation below median, nadir desaturation, and length of oxygen therapy relative to PACU duration...
2017: PloS One
https://www.readbyqxmd.com/read/28456598/two-haplotype-clusters-of-echinococcus-granulosus-sensu-stricto-in-northern-iraq-kurdistan-region-support-the-hypothesis-of-a-parasite-cradle-in-the-middle-east
#13
Zuber Ismael Hassan, Azad Abdullah Meerkhan, Belgees Boufana, Abdullah A Hama, Bayram Dawod Ahmed, Wijdan Mohammed Salih Mero, Serra Orsten, Maria Interisano, Edoardo Pozio, Adriano Casulli
Human cystic echinococcosis (CE) caused by Echinococcus granulosus s.s. is a major public health problem in Iraqi Kurdistan with a reported surgical incidence of 6.3 per 100,000 Arbil inhabitants. A total of 125 Echinococcus isolates retrieved from sheep, goats and cattle were used in this study. Our aim was to determine species/genotypes infecting livestock in Iraqi Kurdistan and examine intraspecific variation and population structure of Echinococcus granulosus s.s. in this region and relate it to that of other regions worldwide...
April 27, 2017: Acta Tropica
https://www.readbyqxmd.com/read/28451501/prevalence-and-outcomes-in-patients-undergoing-reintubation-after-anterior-cervical-spine-surgery-results-from-the-aospine-north-america-multicenter-study-on-8887-patients
#14
Narihito Nagoshi, Michael G Fehlings, Hiroaki Nakashima, Lindsay Tetreault, Jeffrey L Gum, Zachary A Smith, Wellington K Hsu, Chadi A Tannoury, Tony Tannoury, Vincent C Traynelis, Paul M Arnold, Thomas E Mroz, Ziya L Gokaslan, Mohamad Bydon, Anthony F De Giacomo, Bruce C Jobse, Eric M Massicotte, K Daniel Riew
STUDY DESIGN: A multicenter, retrospective cohort study. OBJECTIVE: To evaluate clinical outcomes in patients with reintubation after anterior cervical spine surgery. METHODS: A total of 8887 patients undergoing anterior cervical spine surgery were enrolled in the AOSpine North America Rare Complications of Cervical Spine Surgery study. Patients with or without complications after surgery were included. Demographic and surgical information were collected for patients with reintubation...
April 2017: Global Spine Journal
https://www.readbyqxmd.com/read/28451500/perioperative-vision-loss-in-cervical-spinal-surgery
#15
Brandon C Gabel, Arthur Lam, Jens R Chapman, Rod J Oskouian, Ahmad Nassr, Bradford L Currier, Arjun S Sebastian, Paul M Arnold, Steven R Hamilton, Michael G Fehlings, Thomas E Mroz, K Daniel Riew
STUDY DESIGN: Retrospective multicenter case series. OBJECTIVE: To assess the rate of perioperative vision loss following cervical spinal surgery. METHODS: Medical records for 17 625 patients from 21 high-volume surgical centers from the AOSpine North America Clinical Research Network who received cervical spine surgery (levels from C2 to C7) between January 1, 2005, and December 31, 2011, inclusive, were reviewed to identify occurrences of vision loss following surgery...
April 2017: Global Spine Journal
https://www.readbyqxmd.com/read/28451499/iatrogenic-spinal-cord-injury-resulting-from-cervical-spine-surgery
#16
Alan H Daniels, Robert A Hart, Alan S Hilibrand, David E Fish, Jeffrey C Wang, Elizabeth L Lord, Zorica Buser, P Justin Tortolani, D Alex Stroh, Ahmad Nassr, Bradford L Currier, Arjun S Sebastian, Paul M Arnold, Michael G Fehlings, Thomas E Mroz, K Daniel Riew
STUDY DESIGN: Retrospective cohort study of prospectively collected data. OBJECTIVE: To examine the incidence of iatrogenic spinal cord injury following elective cervical spine surgery. METHODS: A retrospective multicenter case series study involving 21 high-volume surgical centers from the AOSpine North America Clinical Research Network was conducted. Medical records for 17 625 patients who received cervical spine surgery (levels from C2 to C7) between January 1, 2005, and December 31, 2011, were reviewed to identify occurrence of iatrogenic spinal cord injury...
April 2017: Global Spine Journal
https://www.readbyqxmd.com/read/28451498/a-multicenter-review-of-superior-laryngeal-nerve-injury-following-anterior-cervical-spine-surgery
#17
Zachary J Tempel, Justin S Smith, Christopher Shaffrey, Paul M Arnold, Michael G Fehlings, Thomas E Mroz, K Daniel Riew, Adam S Kanter
STUDY DESIGN: A retrospective multicenter case-series study; case report and review of the literature. OBJECTIVE: The anatomy and function of the superior laryngeal nerve (SLN) are well described; however, the consequences of SLN injury remain variable and poorly defined. The prevalence of SLN injury as a consequence of cervical spine surgery is difficult to discern as its clinical manifestations are often inconstant and frequently of a subclinical degree. A multicenter study was performed to better delineate the risk factors, prevalence, and outcomes of SLN injury...
April 2017: Global Spine Journal
https://www.readbyqxmd.com/read/28451496/carotid-artery-injury-in-anterior-cervical-spine-surgery-multicenter-cohort-study-and-literature-review
#18
Roger Härtl, Marjan Alimi, Mohamed Abdelatif Boukebir, Connor D Berlin, Rodrigo Navarro-Ramirez, Paul M Arnold, Michael G Fehlings, Thomas E Mroz, K Daniel Riew
STUDY DESIGN: Retrospective study and literature review. OBJECTIVE: To provide more comprehensive data about carotid artery injury (CAI) or cerebrovascular accident (CVA) related to anterior cervical spine surgery. METHODS: We conducted a retrospective, multicenter, case series study involving 21 high-volume surgical centers from the AOSpine North America Clinical Research Network. Medical records of 17 625 patients who went through cervical spine surgery (levels from C2 to C7) between January 1, 2005, and December 31, 2011, were analyzed...
April 2017: Global Spine Journal
https://www.readbyqxmd.com/read/28451492/recurrent-laryngeal-nerve-palsy-after-cervical-spine-surgery-a-multicenter-aospine-clinical-research-network-study
#19
Ziya L Gokaslan, Mohamad Bydon, Rafael De la Garza-Ramos, Zachary A Smith, Wellington K Hsu, Sheeraz A Qureshi, Samuel K Cho, Evan O Baird, Thomas E Mroz, Michael Fehlings, Paul M Arnold, K Daniel Riew
STUDY DESIGN: Multicenter retrospective study. OBJECTIVES: To investigate the risk of symptomatic recurrent laryngeal nerve palsy (RLNP) following cervical spine surgery, to examine risk factors for its development, and to report its treatment and outcomes. METHODS: A multicenter study from 21 high-volume surgical centers from the AOSpine North America Clinical Research Network was performed. Each center screened for rare complications following cervical spine surgery, including RLNP...
April 2017: Global Spine Journal
https://www.readbyqxmd.com/read/28451490/incidence-and-outcomes-of-acute-implant-extrusion-following-anterior-cervical-spine-surgery
#20
Gabriel A Smith, Jonathan Pace, Mark Corriveau, Sungho Lee, Thomas E Mroz, Ahmad Nassr, Michael G Fehlings, Robert A Hart, Alan S Hilibrand, Paul M Arnold, David B Bumpass, Ziya Gokaslan, Mohamad Bydon, Jeremy L Fogelson, Eric M Massicotte, K Daniel Riew, Michael P Steinmetz
STUDY DESIGN: Multi-institutional retrospective case series of 8887 patients who underwent anterior cervical spine surgery. OBJECTIVE: Anterior decompression from discectomy or corpectomy is not without risk. Surgical morbidity ranges from 9% to 20% and is likely underreported. Little is known of the incidence and effects of rare complications on functional outcomes following anterior spinal surgery. In this retrospective review, we examined implant extrusions (IEs) following anterior cervical fusion...
April 2017: Global Spine Journal
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