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REVIEW
Manuel Frischknecht, Angelina Meier, Bernhard Mani, Lucas Joerg, Olaf Chan-Hi Kim, Katia Boggian, Carol Strahm
BACKGROUND: Tularemia, a zoonotic disease caused by Francisella tularensis, can cause a broad spectrum of disease in humans including six major clinical presentations: the ulceroglandular, glandular, oculoglandular, oropharyngeal, typhoidal and pneumonic form. The epidemiology and ecology and thus transmission of tularemia are complex, depending on conditions unique to specific locations. CASE SERIES AND METHODS: Thirteen cases with different forms of the disease and one very rare case of a myocarditis are reported, discussed, and reviewed within the scope of current literature...
January 17, 2019: Infection
#22
JOURNAL ARTICLE
Paula Donate-Pérez-Molino, Cristian Castelló-Abietar, Jonathan Fernández-Suárez, Juan C de Vicente
No abstract text is available yet for this article.
December 27, 2018: Enfermedades Infecciosas y Microbiología Clínica
#23
JOURNAL ARTICLE
Cristhian Valor, Katherine Huber
A 28-year-old man presented to our clinic over the course of 3 weeks with symptoms that progressed from mild headaches to fever, fatigue, myalgia and an enlarged right preauricular lymph node with ipsilateral conjunctivitis and upper eyelid weakness. Our differential included Epstein Barr Virus/Cytomegalovirus mononucleosis, bacterial conjunctivitis and lymphoma. We evaluated with CBC, EBV IgM Ab, lactate dehydrogenase level and a CMV IgG Ab which were all within normal limits. During his third visit, we discovered our patient had been scratched by two stray kittens he had adopted 2 months prior...
July 6, 2018: BMJ Case Reports
#24
JOURNAL ARTICLE
M Polat, T Karapınar, F Sırmatel
BACKGROUND: Tularaemia is a zoonotic infectious disease caused by Francisella tularensis, an aerobic, uncapsulated, gram-negative coccobacillus. Several case reports have appeared on the dermatological manifestations of tularaemia, but relatively few longer-term studies are available. AIM: To identify skin features of tularaemia that aid in its diagnosis. METHODS: In total, 168 patients (68 male, 100 female) diagnosed with tularaemia were retrospectively examined...
October 2018: Clinical and Experimental Dermatology
#25
REVIEW
Harsh Rawal, Ami Patel, Michael Moran
Tularaemia is a zoonotic infection caused by Francisella tularensis. Ulceroglandular, glandular, oculoglandular, pharyngeal, typhoidal and pneumonic types are the different types of the disease. Infection of prosthetic joints occurs at an exceedingly uncommon rate. We report a case of prosthetic joint infection involving the hip with F. tularensis, which to the best of our knowledge after a thorough literature review is the second of its kind.
October 11, 2017: BMJ Case Reports
#26
JOURNAL ARTICLE
Céline Terrada, Said Azza, Bahram Bodaghi, Phuc Le Hoang, Michel Drancourt
BACKGROUND: Literature reports on ophthalmological manifestations related to tularemia, a zoonose caused by the bacterium Francisella tularensis, largely refer to Parinaud's oculoglandular syndrome, which consists of the association of conjunctivitis with preauricular lymphadenitis. In this paper, we report a case of intraocular inflammation during tularemia infection. CASE PRESENTATION: A 52-year-old Caucasian man was diagnosed with unilateral uveitis. The uveitis was posterior, with a 2+ vitritis and a large yellowish lesion involving the macula with an overlying sub-retinal detachment, extending inferiorly, and subretinal hemorrhages...
September 1, 2016: BMC Ophthalmology
#27
JOURNAL ARTICLE
J Galindo-Bocero, S Sánchez-García, M Álvarez-Coronado, P Rozas-Reyes
CLINICAL CASE: A 33-year old woman presents with unilateral granulomatous conjunctivitis, ipsilateral regional lymphadenopathy and fever. A Bartonella henselae infection is demonstrated by indirect immunofluorescence, and a diagnosis of a Parinaud's oculoglandular syndrome is established. Outcome after treatment with oral doxycycline is satisfactory. DISCUSSION: Parinaud's oculoglandular syndrome is the most frequent ocular manifestation of a Bartonella henselae infection...
January 2017: Archivos de la Sociedad Española de Oftalmología
#28
JOURNAL ARTICLE
Nesrine Abroug, Imen Khairallah-Ksiaa, Rim Kahloun, Sana Khochtali, Sonia Zaouali, Moncef Khairallah
The purpose of this study was to report a case of Parinaud's oculoglandular syndrome associated with subclinical Rickettsia conorii infection. We report a case of a 66-year-old male patient presented with unilateral persistent granulomatous conjunctivitis in the left eye and an ipsilateral preauricular lymphadenopathy without associated systemic features. Laboratory evaluation showed a positive indirect immunofluorescence antibody test for R. conorii. The patient received a 2-week course of oral doxycycline, with subsequent complete resolution of all his symptoms...
October 2015: International Ophthalmology
#29
JOURNAL ARTICLE
Miriam Hernández-Porto, Rocio Sánchez Burgos, Blanca Martínez de Las Heras, Jose Cayetano Rodriguez Luis
No abstract text is available yet for this article.
February 2017: Enfermedades Infecciosas y Microbiología Clínica
#30
JOURNAL ARTICLE
Anthony Corchia, Anne Limelette, Béatrice Hubault, Ailsa Robbins, Anne Quinquenel, Firouze Bani-Sadr, Yohan N'Guyen
BACKGROUND: The rare descriptions, in the literature, of ocular infections due to Pasteurella multocida include: endophtalmitis, keratitis and corneal ulcers, Parinaud's oculoglandular syndrome, and conjunctivitis. Here, we report a rare case of rapidly evolving conjunctivitis due to Pasteurella multocida, occurring after direct inoculation with animal droplets in an immuno-compromised host. CASE PRESENTATION: A 69-year-old, Caucasian male was referred to our department with purulent conjunctivitis, occurring five days after chemotherapy for an angioimmunoblastic-T-cell-lymphoma, and thirty-three hours after being struck in his right eye by his sneezing Dachshund dog...
March 8, 2015: BMC Ophthalmology
#31
JOURNAL ARTICLE
Anthony Corchia, Anne Limelette, Béatrice Hubault, Ailsa Robbins, Anne Quinquenel, Firouze Bani-Sadr, Yohan N'Guyen
BACKGROUND: The rare descriptions, in the literature, of ocular infections due to Pasteurella multocida include: endophtalmitis, keratitis and corneal ulcers, Parinaud's oculoglandular syndrome, and conjunctivitis. Here, we report a rare case of rapidly evolving conjunctivitis due to Pasteurella multocida, occurring after direct inoculation with animal droplets in an immuno-compromised host. CASE PRESENTATION: A 69-year-old, Caucasian male was referred to our department with purulent conjunctivitis, occurring five days after chemotherapy for an angioimmunoblastic-T-cell-lymphoma, and thirty-three hours after being struck in his right eye by his sneezing Dachshund dog...
December 2015: BMC Ophthalmology
#32
JOURNAL ARTICLE
Sebnem Eren Gok, Aysel Kocagul Celikbas, Nurcan Baykam, Ayse Atay Buyukdemirci, Mustafa Necati Eroglu, Ozlem Evren Kemer, Basak Dokuzoguz
INTRODUCTION: Tularemia is a zoonotic disease caused by Francisella tularensis. The oculoglandular form is one of the rarest forms. In this study, evaluated tularemia patients, focusing on the ocular form and the efficacy of early antibiotic therapy. METHODOLOGY: During a tularemia outbreak, the epidemiological and clinical findings, laboratory assays, and drugs used for the treatment of 48 patients were recorded prospectively. The diagnosis of tularemia was confirmed with microagglutination test (MAT) as well as clinical findings...
October 2014: Journal of Infection in Developing Countries
#33
JOURNAL ARTICLE
Engin Şenel, Özgür Satılmış, Bilal Acar
BACKGROUND: Tularemia is a serious and potentially life-threatening zoonosis caused by Francisella tularensis, a highly infective, gram-negative coccobacillus. Although there are plenty of case reports and studies of tularemia outbreaks, the literature is lacking in reports on dermatologic manifestations of the disease. OBJECTIVES: This study aimed to identify skin manifestations in clinical forms of tularemia. METHODS: A total of 151 patients diagnosed with tularemia at Çankırı State Hospital, Çankırı, Turkey, were retrospectively examined...
January 2015: International Journal of Dermatology
#34
JOURNAL ARTICLE
Fatma Oz, Ayse Eksioglu, Gonul Tanır, Gulsum Bayhan, Özge Metin, Turkan Aydın Teke
AIM: The aim of this study was to determine the clinical characteristics and sonographic features of lymphadenopathy (LAP) and to evaluate the treatment modalities and treatment outcomes in children with tularemia. MATERIALS AND METHODS: Demographic characteristics, ultrasonographic and physical examination findings, and treatment outcomes in 55 tularemia patients (24 male and 31 female) with a mean age of 10.8 ± 4.0 years were analyzed retrospectively. Lymph node necrosis was classified in three stages based on ultrasound findings-stage 1, cortical microabscesses; stage 2, cortical and medullar abscesses; stage 3, total necrosis of the lymph node...
August 2014: Vector Borne and Zoonotic Diseases
#35
JOURNAL ARTICLE
İlkay Bozkurt, Selçuk Kiliç
Tularemia is a zoonotic disease caused by Francisella tularensis. Sporadic tularemia cases have been increasingly reported particularly from provinces located at northwest and central regions of Turkey especially during last two decades, as well as waterborne outbreaks reported from almost all regions. Transmission most often occurs through consumption of contaminated water and food, thus, oropharyngeal form is the most common clinical presentation in our country. The aim of this study was to present a small outbreak experience in Afsin, country of Kahramanmaras province located at southern part of Turkey...
July 2014: Mikrobiyoloji Bülteni
#36
MULTICENTER STUDY
H Erdem, D Ozturk-Engin, M Yesilyurt, O Karabay, N Elaldi, G Celebi, N Korkmaz, T Guven, S Sumer, N Tulek, O Ural, G Yilmaz, S Erdinc, S Nayman-Alpat, E Sehmen, C Kader, N Sari, A Engin, G Cicek-Senturk, G Ertem-Tuncer, G Gulen, F Duygu, A Ogutlu, E Ayaslioglu, A Karadenizli, M Meric, M Ulug, C Ataman-Hatipoglu, F Sirmatel, S Cesur, S Comoglu, A Kadanali, A Karakas, A Asan, I Gonen, Y Kurtoglu-Gul, N Altin, S Ozkanli, F Yilmaz-Karadag, M Cabalak, S Gencer, A Umut Pekok, D Yildirim, D Seyman, B Teker, H Yilmaz, K Yasar, I Inanc Balkan, H Turan, M Uguz, S Kilic, Y Akkoyunlu, S Kaya, A Erdem, A Inan, Y Cag, S Bolukcu, A Ulu-Kilic, N Ozgunes, L Gorenek, A Batirel, C Agalar
In this multicentre study, which is the largest case series ever reported, we aimed to describe the features of tularaemia to provide detailed information. We retrospectively included 1034 patients from 41 medical centres. Before the definite diagnosis of tularaemia, tonsillitis (n = 653, 63%) and/or pharyngitis (n = 146, 14%) were the most frequent preliminary diagnoses. The most frequent clinical presentations were oropharyngeal (n = 832, 85.3%), glandular (n = 136, 13.1%) and oculoglandular (n = 105, 10...
December 2014: Clinical Microbiology and Infection
#37
REVIEW
R Kohlmann, G Geis, S G Gatermann
The bacterium Francisella tularensis is known for more than 100 years by now as the etiological agent of the disease tularemia, a zoonotic infection with a worldwide distribution in the Northern Hemisphere. The prevalence of tularemia shows a wide geographic variation, being comparably infrequent in Germany. Tularemia can present itself with multiple clinical manifestations including ulceroglandular, glandular, oropharyngeal, oculoglandular, respiratory and typhoidal forms. Due to the low prevalence and the unspecific symptomatology, a rapid diagnosis and early start of an effective therapy are rarely obtained...
July 2014: Deutsche Medizinische Wochenschrift
#38
JOURNAL ARTICLE
Belgin Gülhan, Hasan Tezer, Saliha Kanık-Yüksek, Selçuk Kılıç, Emrah Senel
Tularemia caused by Francisella tularensis occurs worldwide in the northern hemisphere, with great variation in geographic and temporal occurrence. It generally presents as an acute febrile disease with the major clinical presentations including the six classic forms of tularemia: ulceroglandular, glandular, oculoglandular, oropharyngeal, typhoidal, and pneumonic. In contrast to European countries, where the ulceroglandular form is more prominent, the oropharyngeal form is the most common presentation in Turkey...
March 2014: Turkish Journal of Pediatrics
#39
JOURNAL ARTICLE
Khushbu Shukla, Jaime Fergie
An 11-year-old-girl and a 13-year-old-boy presented with characteristic findings of Parinaud's oculoglandular syndrome. The girl was initially suspected of having Bartonella henselae infection and the boy was initially diagnosed as Francisella tularensis infection. Both children had laboratory-confirmed infection with Rickettsia typhi.
November 2014: Pediatric Infectious Disease Journal
#40
JOURNAL ARTICLE
Muhammet Kosker, Dicle Sener, Omer Kilic, Ferit Akil, Mehmet Yilmaz, Ozcan Ozturk, Haluk Cokugras, Yildiz Camcioglu, Necla Akcakaya
Tularemia is a zoonotic disease of the northern hemisphere. Oculoglandular tularemia is the rarest form, comprising 1.4-4.2% of all cases. We present a patient with oculoglandular tularemia that did not respond to gentamicin to demonstrate the need for prolonged antimicrobial treatment and surgical intervention.
September 2013: Scandinavian Journal of Infectious Diseases
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