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https://www.readbyqxmd.com/read/28860657/pupil-response-components-attention-light-interaction-in-patients-with-parinaud-s-syndrome
#1
Paola Binda, Torsten Straßer, Krunoslav Stingl, Paul Richter, Tobias Peters, Helmut Wilhelm, Barbara Wilhelm, Carina Kelbsch
Covertly shifting attention to a brighter or darker image (without moving one's eyes) is sufficient to evoke pupillary constriction or dilation, respectively. One possibility is that this attentional modulation involves the pupillary light response pathway, which pivots around the olivary pretectal nucleus. We investigate this possibility by studying patients with Parinaud's syndrome, where the normal pupillary light response is strongly impaired due to lesions in the pretectal area. Four patients and nine control participants covertly attended (while maintaining fixation at the center of a monitor screen) to one of two disks located in the left and right periphery: one brighter, the other darker than the background...
August 31, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28837721/visual-function-in-asymptomatic-patients-with-homozygous-sickle-cell-disease-and-temporal-macular-atrophy
#2
Gilles C Martin, Charlotte Dénier, Olivia Zambrowski, David Grévent, Lenaïc Bruère, Valentine Brousse, Mariane de Montalembert, Dominique Brémond-Gignac, Matthieu P Robert
Importance: Temporal macular involvement in sickle cell disease can now easily be detected by optical coherence tomography (OCT). However, while recent studies have demonstrated its high prevalence, little is known about its potential consequences on visual function. Objective: To assess the visual function of patients with sickle cell disease with no visual symptoms despite temporal macular atrophy. Design, Setting, and Participants: This retrospective case series included data collection and explorations made in a single referral center for sickle cell disease in 2016...
October 1, 2017: JAMA Ophthalmology
https://www.readbyqxmd.com/read/28754128/does-air-pollution-play-a-role-in-infertility-a-systematic-review
#3
REVIEW
Julie Carré, Nicolas Gatimel, Jessika Moreau, Jean Parinaud, Roger Léandri
BACKGROUND: Air pollution is involved in many pathologies. These pollutants act through several mechanisms that can affect numerous physiological functions, including reproduction: as endocrine disruptors or reactive oxygen species inducers, and through the formation of DNA adducts and/or epigenetic modifications. We conducted a systematic review of the published literature on the impact of air pollution on reproductive function. Eligible studies were selected from an electronic literature search from the PUBMED database from January 2000 to February 2016 and associated references in published studies...
July 28, 2017: Environmental Health: a Global Access Science Source
https://www.readbyqxmd.com/read/28751141/histology-stratified-tumor-control-and-patient-survival-following-stereotactic-radiosurgery-for-pineal-region-tumors-a-report-from-the-international-gamma-knife-research-foundation
#4
Christian Iorio-Morin, Hideyuki Kano, Marshall Huang, L Dade Lunsford, Gabriela Simonová, Roman Liscak, Or Cohen-Inbar, Jason Sheehan, Cheng-Chia Lee, Hsiu-Mei Wu, David Mathieu
OBJECT: Pineal region tumors represent a rare and histologically diverse group of lesions. Few studies are available to guide management and the outcomes following stereotactic radiosurgery (SRS) are unknown for many histologies. METHODS: Patients who underwent SRS for a pineal region tumor and for whom at least 6 months of imaging follow-up was available were retrospectively assessed in five centers. Data was collected from the medical record and histology-level analyses were performed, including actuarial tumor control and survival analyses...
July 24, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28692759/sperm-morphology-assessment-pathophysiology-clinical-relevance-and-state-of-the-art-in-2017
#5
REVIEW
N Gatimel, J Moreau, J Parinaud, R D Léandri
For over 30 years, sperm morphology assessment has been one of the most common tests in evaluation of fertility. This review examines the clinical relevance of sperm morphology assessment in the diagnosis of infertility and in assisted reproductive technology, as well as its analytical reliability. Publications on the pathophysiology, the analytical reliability of the test and its clinical relevance in diagnosis and in Assisted Reproductive Technology (ART) were evaluated. This review compared and discussed study methodologies and results, including patient characteristics, preparation, smear staining methods and classification systems...
September 2017: Andrology
https://www.readbyqxmd.com/read/28668273/effect-of-unilateral-tubal-abnormalities-on-the-results-of-intrauterine-inseminations
#6
Tiffany Cochet, Nicolas Gatimel, Jessika Moreau, Clémentine Cohade, Carole Fajau, Florence Lesourd, Jean Parinaud, Roger Léandri
A total of 101 patients with one normal tube were compared with 117 patients with two normal tubes to assess the effect of unilateral tubal abnormalities on the results of intrauterine inseminations. The clinical pregnancy and live birth rates seemed to reduce by one-half in almost all types of abnormality, suggesting that these patients should be preferentially treated with IVF.
September 2017: Reproductive Biomedicine Online
https://www.readbyqxmd.com/read/28653396/parinaud-syndrome-any-clinicoradiological-correlation
#7
L Pollak, T Zehavi-Dorin, A Eyal, R Milo, R Huna-Baron
INTRODUCTION: The significance of MRI findings of patients with Parinaud syndrome (PS) with respect to clinical characteristics is poorly defined. Over the past decades, all patients with PS undergo magnetic resonance imaging which allows a better identification of the lesion localization. We compared the neuro-ophthalmological findings of patients with PS caused by intrinsic (intra-axial) vs extrinsic (pineal gland tumor) brainstem lesions. METHODS: Medical records of patients with PS evaluated between 2000 and 2016 were retrospectively reviewed...
June 26, 2017: Acta Neurologica Scandinavica
https://www.readbyqxmd.com/read/28486360/ovarian-mucinous-cystadenoma-after-ovarian-graft
#8
Carole Fajau-Prevot, Yann Tanguy Le Gac, Christine Chevreau, Clémentine Cohade, Nicolas Gatimel, Jean Parinaud, Roger Leandri
BACKGROUND: Freezing strips of ovarian cortex before chemotherapy followed by transplantation is an experimental method to preserve fertility for reproductive-aged women with cancer. We report a case of a cancer patient who developed a mucinous cystadenoma in a grafted piece of ovarian cortex. CASE: A 32-year-old woman with a Ewing sarcoma had ovarian cryopreservation using cortical strip freezing before receiving chemotherapy. Five years later she had no ovarian function, and the strips were thawed and grafted back onto the ovary...
June 2017: Obstetrics and Gynecology
https://www.readbyqxmd.com/read/28452561/follicular-growth-but-absence-of-oocyte-and-cumulus-maturation-during-ovarian-stimulation-in-the-days-following-surgical-abortion-a-case-report
#9
Clémentine Cohade, Jessika Moreau, Nicolas Gatimel, Laurence Gladieff, Jean Parinaud, Roger Leandri
This paper is a case report on the results of an ovarian stimulation performed in the days following an induced abortion. A patient had breast cancer diagnosed during an early pregnancy. She had an induced abortion and had, before chemotherapy an ovarian stimulation, using rFSH and GnRH antagonist, followed by follicular puncture for oocyte for vitrification in the view of fertility preservation. No oocyte could be obtained despite a good hormonal and ultrasonographical follicular growth. This case report suggest that ovarian stimulation must be delayed after abortion to allow the maturation of oocyte-cumulus complexes...
September 2017: Gynecological Endocrinology
https://www.readbyqxmd.com/read/28416623/teaching-neuroimages-acute-parinaud-syndrome
#10
Emily Swinkin, Esther Bui
No abstract text is available yet for this article.
April 18, 2017: Neurology
https://www.readbyqxmd.com/read/28388912/environmental-pollutants-a-possible-etiology-for-premature-ovarian-insufficiency-a-narrative-review-of-animal-and-human-data
#11
REVIEW
Pauline Vabre, Nicolas Gatimel, Jessika Moreau, Véronique Gayrard, Nicole Picard-Hagen, Jean Parinaud, Roger D Leandri
BACKGROUND: Because only 25% of cases of premature ovarian insufficiency (POI) have a known etiology, the aim of this review was to summarize the associations and mechanisms of the impact of the environment on this pathology. Eligible studies were selected from an electronic literature search from the PUBMED database from January 2000 to February 2016 and associated references in published studies. Search terms included ovary, follicle, oocyte, endocrine disruptor, environmental exposure, occupational exposure, environmental contaminant, pesticide, polyaromatic hydrocarbon, polychlorinated biphenyl PCB, phenol, bisphenol, flame retardant, phthalate, dioxin, phytoestrogen, tobacco, smoke, cigarette, cosmetic, xenobiotic...
April 7, 2017: Environmental Health: a Global Access Science Source
https://www.readbyqxmd.com/read/28329721/how-many-embryos-should-be-transferred-a-validated-score-to-predict-ongoing-implantation-rate
#12
Nicolas Gatimel, Melissa Ladj, Carole Teston, Florence Lesourd, Carole Fajau, Clémentine Cohade, Jean Parinaud, Roger D Léandri
OBJECTIVE: To developed a prognostic score to predict ongoing implantation rate according to clinical and biological parameters and to choose the number of embryos to be transferred in patients undergoing IVF/ICSI. STUDY DESIGN: The transfer score was established using multivariate analysis of biological and clinical parameters in 3211 fresh embryo transfers in a retrospective study. Then we validated the score in 694 fresh embryo transfers in a prospective study...
May 2017: European Journal of Obstetrics, Gynecology, and Reproductive Biology
https://www.readbyqxmd.com/read/28247123/identification-of-characteristic-features-of-pineal-germinoma-that-enhance-accuracy-of-preoperative-differentiation-in-pineal-region-tumors-its-significance-on-optimum-surgical-treatment
#13
Akihiro Inoue, Takanori Ohnishi, Shohei Kohno, Shiro Ohue, Shinji Iwata, Shirabe Matsumoto, Masahiro Nishikawa, Saya Ozaki, Yosuke Mizuno, Riko Kitazawa, Takeharu Kunieda
The aim of the study is to identify characteristic features of pineal germinoma that enhance preoperative accuracy in differentiating germinoma from other pineal region tumors. Twenty-one consecutive patients with pineal region tumors were enrolled. In all patients, tumor resection was performed to verify the histology. Clinical records including upward gaze palsy of Parinaud's syndrome and neuroimaging were analyzed. In addition, we evaluated the relationship between magnetic resonance imaging (MRI) findings and tumor progression patterns in pineal germinoma...
March 1, 2017: Neurosurgical Review
https://www.readbyqxmd.com/read/28069468/children-with-dorsal-midbrain-syndrome-as-a-result-of-pineal-tumors
#14
Mary Ellen Hoehn, Julie Calderwood, Thomas O'Donnell, Gregory T Armstrong, Amar Gajjar
BACKGROUND: Dorsal midbrain syndrome (also known as Parinaud syndrome and pretectal syndrome) is a well-known complication of tumors of the pineal region. However, there are few reports regarding outcomes, especially in children. The purpose of this study was to report the ophthalmic outcomes in a group of children with pineal tumors treated at a single institution. METHODS: The medical records of pediatric patients diagnosed with pineal region tumors and evaluated at our ophthalmology clinic were studied retrospectively...
February 2017: Journal of AAPOS: the Official Publication of the American Association for Pediatric Ophthalmology and Strabismus
https://www.readbyqxmd.com/read/28025405/teaching-video-neuroimages-minimal-anomalies-of-dorsal-midbrain-syndrome-parinaud-syndrome
#15
Pilar Rojas, Philippe Maeder, François-Xavier Borruat
No abstract text is available yet for this article.
January 3, 2017: Neurology
https://www.readbyqxmd.com/read/28012404/influence-of-air-quality-on-the-results-of-in-vitro-fertilization-attempts-a-retrospective-study
#16
Julie Carré, Nicolas Gatimel, Jessika Moreau, Jean Parinaud, Roger Leandri
OBJECTIVE: To assess the influence of air quality on the results of IVF. STUDY DESIGN: We performed a retrospective study on 292 patients who have undergone an IVF attempt from April 2012 to December 2015 in our French university hospital. Patients were included in the study if data on the air quality at home and at work were available and if they haven't been gone for more than 4days in a month. Data were recorded during the 3 months before oocyte collection and 1 month after embryo transfer...
March 2017: European Journal of Obstetrics, Gynecology, and Reproductive Biology
https://www.readbyqxmd.com/read/27928096/extremely-late-recurrence-21-years-after-total-removal-of-immature-teratoma-a-case-report-and-literature-review
#17
REVIEW
Yui Mano, Masayuki Kanamori, Toshihiro Kumabe, Ryuta Saito, Mika Watanabe, Yukihiko Sonoda, Teiji Tominaga
Immature teratoma (IMT) is normally treated by resection and adjuvant therapy. The present unusual case of recurrent germinoma occurred 21 years after total resection of pineal IMT. A 3-year-old boy presented with headache, disturbance of consciousness, and Parinaud's syndrome. Magnetic resonance (MR) imaging revealed a pineal mass lesion, and total resection of the tumor was achieved. The histological diagnosis was mature teratoma. He did not receive further treatment, and did well without recurrence for 20 years...
January 15, 2017: Neurologia Medico-chirurgica
https://www.readbyqxmd.com/read/27887717/continued-existence-of-significant-disparities-in-the-technical-practices%C3%A2-of-sperm-morphology-assessment-and-the-clinical-implications-results-of-a-french-questionnaire
#18
Nicolas Gatimel, Lucile Mansoux, Jessika Moreau, Jean Parinaud, Roger D Léandri
OBJECTIVE: To investigate current practices for sperm morphology assessment. DESIGN: E-mail survey questionnaire. SETTING: Diagnostic and clinical institutions/laboratories. PATIENT(S): French biologists and clinicians (n = 225). INTERVENTION(S): None. MAIN OUTCOME MEASURE(S): Answers to 24 questions. RESULT(S): The survey shows that even now in France there is great inconsistency in the use of sperm morphology assessments...
February 2017: Fertility and Sterility
https://www.readbyqxmd.com/read/27824376/changes-to-corneal-aberrations-and-vision-after-monovision-in-patients-with-hyperopia-after-using-a-customized-aspheric-ablation-profile-to-increase-corneal-asphericity-q-factor
#19
Romain Courtin, Alain Saad, Alice Grise-Dulac, Emmanuel Guilbert, Damien Gatinel
PURPOSE: To evaluate the visual outcomes and fourth-order Zernike spherical aberrations induced with a customized change in corneal asphericity (ΔQ) correction of presbyopia combined with monovision for hyperopic patients. METHODS: Consecutive hyperopic patients who underwent presbyopic LASIK between September 2013 and July 2014 were included. For the non-dominant eyes, the aspheric ablation profile associated with a myopic refraction was planned using the Custom-Q nomogram (Alcon Laboratories, Inc...
November 1, 2016: Journal of Refractive Surgery
https://www.readbyqxmd.com/read/27778456/parinaud-syndrome-a-25-year-1991-2016-review-of-40-consecutive-adult-cases
#20
Melissa Shields, Swati Sinkar, WengOnn Chan, John Crompton
PURPOSE: To characterize the clinical features, aetiology and management of ophthalmic symptoms in adult patients with Parinaud syndrome. METHODS: This is a retrospective, non-comparative observational case series. We reviewed 40 consecutive charts of adult patients with the clinical diagnosis of Parinaud syndrome at the Royal Adelaide Hospital Department of Ophthalmology in Adelaide, South Australia, between 1991 and 2016. Charts were reviewed for the following: (1) demographic information, (2) clinical presentation, (3) neuro-ophthalmology signs, (4) aetiology of Parinaud syndrome, and (5) management...
October 24, 2016: Acta Ophthalmologica
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