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https://www.readbyqxmd.com/read/27917836/the-crystal-structure-of-dihydrodipicolinate-reductase-from-the-human-pathogenic-bacterium-bartonella-henselae-strain-houston-1-at-2-3%C3%A2-%C3%A3-resolution
#1
Ali R Cala, Maria T Nadeau, Jan Abendroth, Bart L Staker, Alexandra R Reers, Anthony W Weatherhead, Renwick C J Dobson, Peter J Myler, André O Hudson
In bacteria, the second committed step in the diaminopimelate/lysine anabolic pathways is catalyzed by the enzyme dihydrodipicolinate reductase (DapB). DapB catalyzes the reduction of dihydrodipicolinate to yield tetrahydrodipicolinate. Here, the cloning, expression, purification, crystallization and X-ray diffraction analysis of DapB from the human-pathogenic bacterium Bartonella henselae, the causative bacterium of cat-scratch disease, are reported. Protein crystals were grown in conditions consisting of 5%(w/v) PEG 4000, 200 mM sodium acetate, 100 mM sodium citrate tribasic pH 5...
December 1, 2016: Acta Crystallographica. Section F, Structural Biology Communications
https://www.readbyqxmd.com/read/27872616/novel-approach-for-evaluation-of-bacteroides-fragilis-protective-role-against-bartonella-henselae-liver-damage-in-immunocompromised-murine-model
#2
Chiara Pagliuca, Annunziata G Cicatiello, Roberta Colicchio, Adelaide Greco, Raimondo Cerciello, Luigi Auletta, Sandra Albanese, Elena Scaglione, Caterina Pagliarulo, Gabiria Pastore, Gelsomina Mansueto, Arturo Brunetti, Bice Avallone, Paola Salvatore
Bartonella henselae is a gram-negative facultative intracellular bacterium and is the causative agent of cat-scratch disease. Our previous data have established that Bacteroides fragilis colonization is able to prevent B. henselae damages through the polysaccharide A (PSA) in an experimental murine model. In order to determine whether the PSA is essential for the protection against pathogenic effects of B. henselae in immunocompromised hosts, SCID mice were co-infected with B. fragilis wild type or its mutant B...
2016: Frontiers in Microbiology
https://www.readbyqxmd.com/read/27843905/cat-scratch-disease-expanded-spectrum
#3
Hassan A Aziz, Thomas P Plesec, Camille Sabella, Unni K Udayasankar, Arun D Singh
BACKGROUND: To expand the spectrum of ophthalmic manifestations in cat scratch disease. METHODS: Case report. RESULTS: A 7-year-old male was referred for evaluation of his left optic disc after failing vision screening test at school. His visual acuity was 20/20 OD and light perception OS. Fundus examination showed a left optic disc lesion associated with an exudative retinal detachment and vitreous seeding. Ultrasonography revealed a 7 × 7...
October 2016: Ocular Oncology and Pathology
https://www.readbyqxmd.com/read/27827898/a-comparative-study-of-dog-and-cat-induced-injury-on-incidence-and-risk-factors-among-children
#4
Ying Chen, Yang Gao, Li Zhou, Yafei Tan, Liping Li
Background: Millions of people are bitten by animals each year, with approximately 90% of the injuries being caused by dogs and cats. However, few studies focus on risk factors of dog- and cat-induced injury in China. Therefore, the objective of this study was to investigate the rate of dog- and cat-induced injury and its potential risk factors. Methods: The data were from a population-based cross-sectional study conducted in 2015, with a sample of 9380 children 6-19 years of age from two cities, Shenzhen (large city) and Shantou (mid-sized city), in southern China...
November 3, 2016: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/27662446/thoracic-osteomyelitis-and-epidural-abscess-formation-due-to-cat-scratch-disease-case-report
#5
David Dornbos, Jocelyn Morin, Joshua R Watson, Jonathan Pindrik
Osteomyelitis of the spine with associated spinal epidural abscess represents an uncommon entity in the pediatric population, requiring prompt evaluation and diagnosis to prevent neurological compromise. Cat scratch disease, caused by the pathogen Bartonella henselae, encompasses a wide spectrum of clinical presentations; however, an association with osteomyelitis and epidural abscess has been reported in only 4 other instances in the literature. The authors report a rare case of multifocal thoracic osteomyelitis with an epidural abscess in a patient with a biopsy-proven pathogen of cat scratch disease...
December 2016: Journal of Neurosurgery. Pediatrics
https://www.readbyqxmd.com/read/27648778/cat-scratch-disease-in-the-united-states-2005-2013
#6
Christina A Nelson, Shubhayu Saha, Paul S Mead
Cat-scratch disease (CSD) is mostly preventable. More information about the epidemiology and extent of CSD would help direct prevention efforts to those at highest risk. To gain such information, we reviewed the 2005-2013 MarketScan national health insurance claims databases and identified patients <65 years of age with an inpatient admission or outpatient visit that included a CSD code from the International Classification of Diseases, Ninth Revision, Clinical Modification. Incidence of CSD was highest among those who lived in the southern United States (6...
October 2016: Emerging Infectious Diseases
https://www.readbyqxmd.com/read/27598290/-seroprevalence-of-bartonella-henselae-in-occupational-risk-persons
#7
Ignacio Troncoso, Christof Fischer, Francisca Arteaga, Cristian Espinoza, Teresa Azócar, Katia Abarca
INTRODUCTION: Bartonella henselae infection is a worldwide zoonosis with the domestic cat as reservoir. Although people with occupational contact with these pets are risk population only few studies of prevalence in them have been reported. METHODS: A study of seroprevalence of B. henselae was performed to veterinaries and other persons with occupational contact with cats, residents from the Bío-Bío region of Chile. Serum IgG antibodies against B. henselae were determined by indirect immunofluorescence (IFI)...
June 2016: Revista Chilena de Infectología: órgano Oficial de la Sociedad Chilena de Infectología
https://www.readbyqxmd.com/read/27598022/role-of-whole-body-mr-with-dwibs-in-child-s-bartonellosis
#8
E Rossi, A Perrone, D Narese, M Cangelosi, S Sollai, A Semeraro, M Mortilla, C Defilippi
Cat-scratch disease (CSD) is a zoonosis in children, result of infection by Bartonella henselae, a gram-negative bacillus. Infection is generally characterized by regional and self-limited lymphadenopathy after exposure to a scratch or bite from a cat. Rarely, B. henselae is cause of fever of unknown origin (FUO), with dissemination to various organs, most often involving the reticuloendothelial system (liver, spleen, bone marrow), mimicking an inflammatory rather than a lymphoproliferative disease. Whole-body Magnetic Resonance Imaging (WBMRI), in association with diffusion-weighted imaging (DWIBS), allows a comprehensive evaluation of pediatric patients, without the risks inherent to ionizing radiation...
July 2016: La Clinica Terapeutica
https://www.readbyqxmd.com/read/27580771/cat-scratch-colon-in-a-patient-with-lymphocytic-colitis
#9
June Seok Song, Dong Soo Han
No abstract text is available yet for this article.
September 2016: American Journal of Gastroenterology
https://www.readbyqxmd.com/read/27550205/middle-ear-polyps-results-of-traction-avulsion-after-a-lateral-approach-to-the-ear-canal-in-62-cats-2004-2014
#10
Sara Ds Janssens, Annika N Haagsman, Gert Ter Haar
OBJECTIVES: The objective of this study was to report the surgical outcome and complication rate of deep traction avulsion (TA) of feline aural inflammatory polyps after a lateral approach (LA) to the ear canal. METHODS: This was a retrospective analysis of data retrieved from an electronic database of 62 cats treated with TA after an LA (TALA) for removal of ear canal polyps. Long-term outcome was assessed via a telephone questionnaire survey with the owners. RESULTS: Domestic shorthair cats (48%) and Maine Coons (37%) were over-represented...
August 22, 2016: Journal of Feline Medicine and Surgery
https://www.readbyqxmd.com/read/27544345/prosthetic-joint-infection-caused-by-pasteurella-multocida-a-case-series-and-review-of-literature
#11
Estelle Honnorat, Piseth Seng, Hélène Savini, Pierre-Olivier Pinelli, Fabrice Simon, Andreas Stein
BACKGROUND: Pasteurella multocida is a well-recognized zoonotic agent following dog or cat bites or scratches. Nevertheless, prosthetic joint infection caused by P. multocida are rarely reported. METHOD: We report here a series of six cases of prosthetic joint infection caused by P. multocida managed at a referral centre for the treatment of bone and joint infection in southern France. We also reviewed the 26 cases reported in literature. RESULTS: The mean age of our cases was 74 years [±8...
2016: BMC Infectious Diseases
https://www.readbyqxmd.com/read/27484614/atypical-cat-scratch-disease-with-hepatosplenic-involvement
#12
Sean K Verma, Angel Martin, Jose A Montero
No abstract text is available yet for this article.
July 30, 2016: Clinical Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/27446604/ultrasound-imaging-as-the-basis-of-a-clinical-diagnosis-of-systemic-bartonellosis-in-a-patient-after-bone-marrow-transplantation-a-case-report
#13
Aleksandra Krasowska-Kwiecień, Jolanta Goździk, Magdalena Woźniak, Wojciech Czogała
Infections in immunocompromised patients after hematopoietic stem cell transplantation can have a severe and atypical course. Some opportunistic pathogens are difficult to detect in microbiological tests, and that is why treatment success depends on an accurate clinical diagnosis. This article presents a case of a 7-year-old girl with severe aplastic anemia treated with bone marrow transplantation with post-transplantation period complicated by persistent, hectic fever, with peak episodes of 39-40°C, lasting several weeks...
June 2016: Journal of Ultrasonography
https://www.readbyqxmd.com/read/27426218/cat-scratch-disease-presenting-as-parotid-gland-abscess-and-aseptic-meningitis
#14
Juan Carlos García García, Manuel Jesús Núñez Fernández, Aránzazu Portillo Barrio, José Antonio Oteo Revuelta
No abstract text is available yet for this article.
July 14, 2016: Enfermedades Infecciosas y Microbiología Clínica
https://www.readbyqxmd.com/read/27423149/anesthetic-activity-of-alfaxalone-compared-with-ketamine-in-mice
#15
Parkpoom Siriarchavatana, Jessica D Ayers, Lon V Kendall
Alfaxalone encased in hydroxypropyl-β -cyclodextrin is a neuroactive steroid compound that has recently been approved in the United States for use as an anesthetic in dogs and cats. We evaluated the use of alfaxalone compared with ketamine, both alone and in combination with xylazine, for anesthesia of C57BL/6 mice. We assessed time to onset of anesthesia, duration of action, reflex responses, respiratory rate, and clinical signs. Alfaxalone (80 mg/kg IP) induced a light surgical plane of anesthesia in all mice, with a time to onset of 2...
2016: Journal of the American Association for Laboratory Animal Science: JAALAS
https://www.readbyqxmd.com/read/27366169/a-case-of-polyarticular-pasteurella-multocida-septic-arthritis
#16
Sarah Nitoslawski, Todd M McConnell, Makeda Semret, Michael A Stein
A 76-year-old man with a history of osteoarthritis presents with right leg erythema and inability to weight-bear and pain in his right shoulder. Synovial fluid cell count of the knee and shoulder showed abundant neutrophils, and cultures of the knee showed growth of Pasteurella multocida. The patient owned four cats with which he had frequent contact, but history and physical examination elicited no evidence of scratches or bites. This case highlights the invasive potential of Pasteurella multocida in an immunocompetent individual and its capacity to cause septic arthritis in the setting of frequent animal contact...
2016: Canadian Journal of Infectious Diseases & Medical Microbiology
https://www.readbyqxmd.com/read/27364692/lick-of-death-capnocytophaga-canimorsus-is-an-important-cause-of-sepsis-in-the-elderly
#17
James P Wilson, Kalman Kafetz, Douglas Fink
A 70-year-old Caucasian woman was treated for Capnocytophaga canimorsus septicaemia. The source of bacteraemia was very likely to be her household pet, an Italian greyhound. The patient presented with a presumed complex partial seizure but deteriorated rapidly with sepsis and multiorgan dysfunction. Neither scratch nor bite was established, although close petting including licks was reported. Blood cultures grew Gram-negative rods, identified by molecular techniques as C. canimorsus-a bacterium frequently isolated in the oral cavities of dogs and cats...
2016: BMJ Case Reports
https://www.readbyqxmd.com/read/27327290/a-focal-chorioretinal-bartonella-lesion-analyzed-by-optical-coherence-tomography-angiography
#18
Francesco Pichi, Sunil K Srivastava, Ashleigh Levinson, Kimberly M Baynes, Caitlyn Traut, Careen Y Lowder
Neovascularization may be associated with cat-scratch neuroretinitis in the absence of retinal vascular occlusion. Bartonella organisms establish an intimate relationship with the vascular endothelium, causing angioproliferative lesions, which might represent a dedicated pathogenic strategy for expanding the bacterial host cell habitat. In the eye, pathological angiogenesis caused by Bartonella has been described as peripapillary or macular choroidal neovascularization, but the presence of neovascularization within foci of chorioretinitis has never before been reported...
June 1, 2016: Ophthalmic Surgery, Lasers & Imaging Retina
https://www.readbyqxmd.com/read/27312684/cat-scratch-disease-in-a-renal-transplant-recipient
#19
Serkan Feyyaz Yalin, Serdar Sahin, Mucahit Yemisen, Nukhet Tuzuner, Mehmet Riza Altiparmak, Nurhan Seyahi
Cat scratch disease (CSD) is a disorder characterized by self-limited regional lymphadenopathy and fever. We reported a case of CSD in a kidney transplant recipient who presented with fever and lymphadenopathy. Lymph node biopsy demonstrated bacterial histiocytic lymphadenitis. The patient was diagnosed with CSD. Patient had good clinical improvement after treatment. Therefore, CSD should also be borne in mind for kidney recipients though CSD had been infrequently reported in this group.
September 2016: Progress in Transplantation
https://www.readbyqxmd.com/read/27262077/encephalitis-with-convulsive-status-in-an-immunocompetent-pediatric-patient-caused-by-bartonella-henselae
#20
REVIEW
Rosario Cerpa Polar, Gabriela Orellana, Wilmer Silva Caso, José Sánchez Carbonel, Javier Santisteban, Juana Del Valle Mendoza, Javier Santisteban
Cat scratch's disease caused by Bartonella henselae, is known to be a self-limited benign process in immunocompetent children. The association with neurologic manifestations is very uncommon especially in patient with no immunologic defects and in cases without specific treatment. A 7 years old male patient, without any immunocompromised defect, presented an atypic presentation of the cat scratch disease. The patient came to the hospital in two opportunities in a status epilepticus, in both cases the diagnosis was encephalitis by Bartonella henselae and the evolution with treatment was monitored with PCR (polymerase chain reaction) in cerebrospinal fluid and blood, as well as IFI (IgM, IgG) serology (indirect immunofluorescence)...
June 2016: Asian Pacific Journal of Tropical Medicine
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