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https://www.readbyqxmd.com/read/28109584/net-effects-of-nitrogen-fertilization-on-the-nutritive-value-and-digestibility-of-oat-forages
#1
W K Coblentz, M S Akins, J S Cavadini, W E Jokela
Applications of soil amendments containing N are part of routine forage-management strategies for grasses, with a primary goal of increasing forage yield. However, the effects of N fertilization on forage nutritive value, estimates of energy density, and in vitro dry matter or neutral detergent fiber disappearance sometimes have been erratic or inconsistent. Our objectives were to evaluate the effects of N fertilization on the nutritive value of a single cultivar (ForagePlus, Kratz Farms, Slinger, WI) of fall-grown oat fertilized at planting with 20, 40, 60, 80, or 100 kg of N/ha of urea or 2 rates of dairy slurry (42,300 or 84,600 L/ha)...
January 18, 2017: Journal of Dairy Science
https://www.readbyqxmd.com/read/28107910/nanobody-based-enzyme-immunoassay-for-ochratoxin-a-in-cereal-with-high-resistance-to-matrix-interference
#2
Xing Liu, Zongwen Tang, Zhenhua Duan, Zhenyun He, Mei Shu, Xianxian Wang, Shirley J Gee, Bruce D Hammock, Yang Xu
A sensitive indirect competitive nanobody-based enzyme linked immunosorbent assay (Nb-ELISA) for ochratoxin A (OTA) with high resistance to cereal matrix interference was developed. Nanobodies against OTA (Nb15, Nb28, Nb32, Nb36) were expressed in E. coli cells and their thermal stabilities were compared with that of an OTA-specific monoclonal antibody 6H8. All nanobodies could still retain their antigen-binding activity after exposure to temperature 95°C for 5min or to 90°C for 75min. Nb28 that exhibited the highest sensitivity in ELISA was selected for further research...
March 1, 2017: Talanta
https://www.readbyqxmd.com/read/28107445/beta-glucans-supplementation-associates-with-reduction-in-p-cresyl-sulfate-levels-and-improved-endothelial-vascular-reactivity-in-healthy-individuals
#3
Carmela Cosola, Maria De Angelis, Maria Teresa Rocchetti, Eustacchio Montemurno, Valentina Maranzano, Giuseppe Dalfino, Carlo Manno, Annapaola Zito, Michele Gesualdo, Marco Matteo Ciccone, Marco Gobbetti, Loreto Gesualdo
BACKGROUND: Oat and barley beta-glucans are prebiotic fibers known for their cholesterol-lowering activity, but their action on the human gut microbiota metabolism is still under research. Although the induction of short-chain fatty acids (SCFA) following their ingestion has previously been reported, no study has investigated their effects on proteolytic uremic toxins p-cresyl sulfate (pCS) and indoxyl sulfate (IS) levels, while others have failed to demonstrate an effect on the endothelial function measured through flow-mediated dilation (FMD)...
2017: PloS One
https://www.readbyqxmd.com/read/28104998/clinical-assessments-and-care-interventions-to-promote-oral-hydration-amongst-older-patients-a-narrative-systematic-review
#4
Lloyd L Oates, Christopher I Price
BACKGROUND: Older patients in hospital may be unable to maintain hydration by drinking, leading to intravenous fluid replacement, complications and a longer length of stay. We undertook a systematic review to describe clinical assessment tools which identify patients at risk of insufficient oral fluid intake and the impact of simple interventions to promote drinking, in hospital and care home settings. METHOD: MEDLINE, CINAHL, and EMBASE databases and two internet search engines (Google and Google Scholar) were examined...
2017: BMC Nursing
https://www.readbyqxmd.com/read/28099762/human-transporters-pept1-2-facilitate-melatonin-transportation-into-mitochondria-of-cancer-cells-an-implication-of-the-therapeutic-potential
#5
Xiaokui Huo, Chao Wang, Zhenlong Yu, Yulin Peng, Shumei Wang, Shengnan Feng, Shouji Zhang, Xiangge Tian, Chengpeng Sun, Kexin Liu, Sa Deng, Xiaochi Ma
Melatonin is present in virtually all organisms from bacteria to mammals, and it exhibits a broad spectrum of biological functions, including synchronization of circadian rhythms and oncostatic activity. Several functions of melatonin are mediated by its membrane receptors but others are receptor-independent. For the latter, melatonin is required to penetrate membrane and enters intracellular compartments. However, the mechanism by which melatonin enters cells remains debatable. In the current study, it was identified that melatonin and its sulfation metabolites were the substrates of oligopeptide transporter (PEPT) 1/2 and organic anion transporter (OAT) 3, respectively...
January 18, 2017: Journal of Pineal Research
https://www.readbyqxmd.com/read/28099443/inhibition-of-human-drug-transporter-activities-by-the-pyrethroid-pesticides-allethrin-and-tetramethrin
#6
Lisa Chedik, Arnaud Bruyere, Marc Le Vee, Bruno Stieger, Claire Denizot, Yannick Parmentier, Sophie Potin, Olivier Fardel
Pyrethroids are widely-used chemical insecticides, to which humans are commonly exposed, and known to alter functional expression of drug metabolizing enzymes. Limited data have additionally suggested that drug transporters, that constitute key-actors of the drug detoxification system, may also be targeted by pyrethroids. The present study was therefore designed to analyze the potential regulatory effects of these pesticides towards activities of main ATP-binding cassette (ABC) and solute carrier (SLC) drug transporters, using transporter-overexpressing cells...
2017: PloS One
https://www.readbyqxmd.com/read/28093031/the-inhibitory-effects-of-five-alkaloids-on-the-substrate-transport-mediated-through-human-organic-anion-and-cation-transporters
#7
Tahiatul Shams, Xiaoxi Lu, Ling Zhu, Fanfan Zhou
1. Human Solute Carrier Transporters (SLCs) are important membrane proteins mediate the cellular transport of many endogenous and exogenous substances. Organic anion/cation transporters (OATs/OCTs) and Organic anion transporting polypeptides (OATPs) are essential SLCs involved in drug influx. Drug-drug/herb interactions through competing for specific SLCs often lead to unsatisfied therapeutic outcomes and/or unwanted side effects. In this study we comprehensively investigated the inhibitory effects of five clinically relevant alkaloids (dendrobine, matrine, oxymatrine, tryptanthrin and chelerythrine) on the substrate transport through several OATs/OCTs and OATPs...
January 17, 2017: Xenobiotica; the Fate of Foreign Compounds in Biological Systems
https://www.readbyqxmd.com/read/28089080/salba-chia-salvia-hispanica-l-in-the-treatment-of-overweight-and-obese-patients-with-type-2-diabetes-a-double-blind-randomized-controlled-trial
#8
V Vuksan, A L Jenkins, C Brissette, L Choleva, E Jovanovski, A L Gibbs, R P Bazinet, F Au-Yeung, A Zurbau, H V T Ho, L Duvnjak, J L Sievenpiper, R G Josse, A Hanna
BACKGROUND AND AIM: Preliminary findings indicate that consumption of Salba-chia (Salvia hispanica L.), an ancient seed, improves management of type 2 diabetes and suppresses appetite. The aim of this study was to assesse the effect of Salba-chia on body weight, visceral obesity and obesity-related risk factors in overweight and obese adults with type 2 diabetes. METHODS: A double-blind, randomized, controlled trial with two parallel groups involved 77 overweight or obese patients with type 2 diabetes (HbA1c: 6...
December 9, 2016: Nutrition, Metabolism, and Cardiovascular Diseases: NMCD
https://www.readbyqxmd.com/read/28088418/laboratory-silo-type-and-inoculation-effects-on-nutritional-composition-fermentation-and-bacterial-and-fungal-communities-of-oat-silage
#9
J J Romero, Y Zhao, M A Balseca-Paredes, F Tiezzi, E Gutierrez-Rodriguez, M S Castillo
The objectives were to evaluate (1) the use of 2 types of experimental silos (S) to characterize whole-crop oat (Avena sativa L.) silage with or without addition of an inoculant (I), and (2) the effect of inoculation on the microbial community structure of oats ensiled using only plastic bucket silos (BKT). From each of 6 sections in a field, oats were harvested, treated (INO) or not (CON) with inoculant, packed into 19-L BKT or vacuum bags (BG), and ensiled for 217 d. The inoculant added contained Lactobacillus buchneri and Pediococcus pentosaceus (4 × 10(5) and 1 × 10(5) cfu/g of fresh oats, respectively)...
January 11, 2017: Journal of Dairy Science
https://www.readbyqxmd.com/read/28088084/correlates-of-anti-hepatitis-c-positivity-and-use-of-harm-reduction-services-among-people-who-inject-drugs-in-two-cities-in-croatia
#10
Senad Handanagic, Sandra Sevic, Jelena Barbaric, Zoran Dominkovic, Oktavija Dakovic Rode, Josip Begovac, Ivana Bozicevic
BACKGROUND: We assessed correlates of anti-hepatitis C (anti-HCV) positivity and utilization of needle and syringe exchange programs (NSEP) and opioid agonist treatment (OAT) among people who inject drugs (PWID) in two Croatian cities. METHODS: We conducted a cross-sectional study using respondent-driven (RDS) sampling among PWID in Rijeka (N=255) and Split (N=399). We used RDS-weighted population estimates and multivariable logistic regression to explore correlates of anti-HCV positivity and NSEP and OAT utilization...
December 7, 2016: Drug and Alcohol Dependence
https://www.readbyqxmd.com/read/28087986/barriers-to-access-to-opioid-medicines-for-patients-with-opioid-dependence-a-review-of-legislation-and-regulations-in-eleven-central-and-eastern-european-countries
#11
Marjolein J M Vranken, Aukje K Mantel-Teeuwisse, Saskia Jünger, Lukas Radbruch, Willem Scholten, John A Lisman, Marija Subataite, Marie-Hélène D B Schutjens
BACKGROUND AND AIMS: Barriers linked to drug control systems are considered to contribute to inequitable access to controlled medicines, leaving millions of people in pain and suffering. Most studies focus on access to opioids for the treatment of severe (cancer) pain. This study aims to identify specific access barriers for patients with opioid dependence in legislation and regulations of 11 Central and Eastern European countries. METHODS: This study builds on a previous analysis of legislation and regulations as part of the EU 7th Framework Access To Opioid Medication in Europe (ATOME) project...
January 14, 2017: Addiction
https://www.readbyqxmd.com/read/28076661/impression-techniques-used-for-single-unit-crowns-findings-from-the-national-dental-practice-based-research-network
#12
Michael S McCracken, David R Louis, Mark S Litaker, Helena M Minyé, Thomas Oates, Valeria V Gordan, Don G Marshall, Cyril Meyerowitz, Gregg H Gilbert
PURPOSE: To: (1) determine which impression and gingival displacement techniques practitioners use for single-unit crowns on natural teeth; and (2) test whether certain dentist and practice characteristics are significantly associated with the use of these techniques. MATERIALS AND METHODS: Dentists participating in the National Dental Practice-Based Research Network were eligible for this survey study. The study used a questionnaire developed by clinicians, statisticians, laboratory technicians, and survey experts...
January 11, 2017: Journal of Prosthodontics: Official Journal of the American College of Prosthodontists
https://www.readbyqxmd.com/read/28073905/feeding-by-melanaphis-sacchari-hemiptera-aphididae-facilitates-use-of-sorghum-by-rhopalosiphum-padi-hemiptera-aphididae-but-reciprocal-effects-are-negative
#13
J P Michaud, Yun Zhang, Clint Bain
In the process of feeding, aphids modify the physiology of their host plants in species-specific ways, and plant responses to these aggressions are often genotype- or cultivar-specific. Thus, different aphid species sharing a host can influence each other's fitness via plant-mediated interactions, usually with negative and asymmetric impacts. Here, we show that feeding by the sugarcane aphid, Melanaphis sacchari Zehntner, can improve the suitability of sorghum as a host plant for the bird cherry-oat aphid, Rhopalosiphum padi L...
January 10, 2017: Environmental Entomology
https://www.readbyqxmd.com/read/28073432/common-urologic-diseases-in-older-men-and-their-treatment-how-they-impact-fertility
#14
REVIEW
Gabriella Avellino, Didi Theva, Robert D Oates
As men age, medical and surgical diseases involving the genitourinary tract become more common. The conditions themselves, if not their treatments, can negatively impact the fertility potential of an affected man. Many older men maintain the desire to father children, so it is critical to understand the disturbed anatomy and physiology involved to properly counsel that individual. Should this or that treatment regimen be employed? Should sperm banking be undertaken before institution of a permanently ablative/suppressive therapy? What are the long-term consequences of one therapy over another vis-à-vis sperm production, sperm quality, and/or sperm transport? In this context, some of the more common genitourinary afflictions of the older male and the treatment options that are available will be discussed...
January 7, 2017: Fertility and Sterility
https://www.readbyqxmd.com/read/28068147/do-wellness-tourists-get-well-an-observational-study-of-multiple-dimensions-of-health-and-well-being-after-a-week-long-retreat
#15
Marc M Cohen, Fiona Elliott, Liza Oates, Adrian Schembri, Nitin Mantri
BACKGROUND: Wellness retreats use many complementary and alternative therapies within a holistic residential setting, yet few studies have evaluated the effect of retreat experiences on multiple dimensions of health and well-being, and no published studies have reported health outcomes in wellness tourists. OBJECTIVES: To assess the effect of a week-long wellness-retreat experience in wellness tourists. DESIGN: A longitudinal observational study with outcomes assessed upon arrival and departure and 6 weeks after the retreat...
January 9, 2017: Journal of Alternative and Complementary Medicine: Research on Paradigm, Practice, and Policy
https://www.readbyqxmd.com/read/28067025/whole-grain-oats-more-than-just-a-fiber-role-of-unique-phytochemicals
#16
REVIEW
Shengmin Sang, YiFang Chu
Oats are a good source of soluble dietary fiber, especially β-glucan, which has outstanding functional and nutritional properties. β-Glucan is considered to be the major active component of oats because of its cholesterol-lowering and anti-diabetic effects. However, the nutritional benefits of oats appear to go beyond fiber to bioactive phytochemicals with strong antioxidant and anti-inflammatory effects. In this review, we summarize current knowledge on the chemistry, stability, bioavailability, and health effects of two unique phytochemicals in oats, avenanthramides (AVAs) and avenacosides A and B...
January 9, 2017: Molecular Nutrition & Food Research
https://www.readbyqxmd.com/read/28062178/testicular-shear-wave-elastography-in-normal-and-infertile-men-a-prospective-study-on-601-patients
#17
Laurence Rocher, Aline Criton, Jean-Luc Gennisson, Vincent Izard, Sophie Ferlicot, Mickael Tanter, Gerard Benoit, Marie France Bellin, Jean-Michel Correas
Our aim in the study described here was to prospectively establish the feasibility of using and reproducibility of testicular shear-wave elastography in the assessment of testicular stiffness in 62 normal patients and 539 infertile men with obstructive azoospermia (OA), non-Klinefelter syndrome non-obstructive azoospermia (non-KS NOA), Klinefelter syndrome NOA (KS NOA), oligoasthenoteratozoospermia (OAT) or a left varicocele. The feasibility rate was 96.9%, with an intra-class correlation coefficient of 0.85 (95% confidence interval: 0...
January 3, 2017: Ultrasound in Medicine & Biology
https://www.readbyqxmd.com/read/28058714/a-phytotherapic-approach-to-reduce-sperm-dna-fragmentation-in-patients-with-male-infertility
#18
Marco Capece, Giuseppe Romeo, Antonio Ruffo, Leo Romis, Salvatore Mordente, Giovanni Di Lauro
INTRODUCTION: Infertility affects 50 to 80 million (between 8 and 12% of couples). Male factor is a cause of infertility in almost half of the cases, mainly due to oligoasthenoteratozoospermia. DNA fragmentation is now considered an important factor in the aetiology of male infertility. We studied the effects on semen analysis and on DNA fragmentation of in vivo admnistration of Myo-Inositol and Tribulus Terrestris plus Alga Ecklonia plus Biovis (Tradafertil; Tradapharma Sagl, Swizerland) in men with previously diagnosed male infertility...
December 28, 2016: Urologia
https://www.readbyqxmd.com/read/28056527/osteochondral-allograft-transplantation-of-the-knee
#19
Rachel M Frank, Simon Lee, David Levy, Sarah Poland, Maggie Smith, Nina Scalise, Gregory L Cvetanovich, Brian J Cole
BACKGROUND: Osteochondral allograft transplantation (OAT) is being performed with increasing frequency, and the need for reoperations is not uncommon. PURPOSE: To quantify survival for OAT and report findings at reoperations. STUDY DESIGN: Case series; Level of evidence, 4. METHODS: A review of prospectively collected data of 224 consecutive patients who underwent OAT by a single surgeon with a minimum follow-up of 2 years was conducted...
December 1, 2016: American Journal of Sports Medicine
https://www.readbyqxmd.com/read/28056054/effect-of-dietary-types-on-feed-intakes-growth-performance-and-economic-benefit-in-tibetan-sheep-and-yaks-on-the-qinghai-tibet-plateau-during-cold-season
#20
Tianwei Xu, Shixiao Xu, Linyong Hu, Na Zhao, Zhe Liu, Li Ma, Hongjin Liu, Xinquan Zhao
Pastoralists on the Tibetan alpine rangeland suffered great economic loss in cold season, due to serious live-weight loss of domestic livestock under traditional grazing management. This study aimed to evaluate the effect of dietary types (crude protein levels) on feed intakes, growth performance and economic returns of local Tibetan sheep and yaks during cold season. Twenty-four yearling Tibetan sheep (25.29±3.95 kg LW) and twenty two-year-old yaks (100.62±4.55 kg LW) with familiar body conditions were randomly assigned to four groups, fed oats hay (OH), oats silage (OS), total mixed ration (TMR) and traditionally grazed on the local cool-season pasture (TG), respectively, over a 135-day experiment...
2017: PloS One
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