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Cold and weight loss

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https://www.readbyqxmd.com/read/29784900/irak-inhibitor-protects-the-intestinal-tract-of-necrotizing-enterocolitis-by-inhibiting-the-toll-like-receptor-tlr-inflammatory-signaling-pathway-in-rats
#1
Yu Hou, Xin Lu, Yueju Zhang
BACKGROUND The aim of this study was to assess the effects of interleukin-1 (IL-1) receptor associated kinase (IRAK) inhibitors on intestinal injury induced by necrotizing enterocolitis (NEC) in neonatal rats and its regulation on the intestinal Toll-like receptor (TLR) inflammatory signaling pathway. MATERIAL AND METHODS The neonatal rat models of NEC were established though hypoxia-cold stimulation. All rats were divided into 3 groups: an NEC model group (NEC group), an IRAK inhibitor group (IRAKI group), and a normal control group (NC group)...
May 22, 2018: Medical Science Monitor: International Medical Journal of Experimental and Clinical Research
https://www.readbyqxmd.com/read/29741929/is-activation-of-human-brown-adipose-tissue-a-viable-target-for-weight-management
#2
Kara L Marlatt, Kong Y Chen, Eric Ravussin
To date, human studies show that BAT contributes a small, yet highly variable amount to overall energy expenditure. No studies have shown a decrease in body weight with cold-induced BAT activation, and existing pharmacologic studies suggest that BAT activation via the sympathetic nervous system may result in increased heart rate and systolic blood pressure. Furthermore, even though the amount and/or activity of BAT have been shown to vary with seasons, such variation does not seem to be translated into weight changes...
May 9, 2018: American Journal of Physiology. Regulatory, Integrative and Comparative Physiology
https://www.readbyqxmd.com/read/29739454/l-menthol-attenuates-the-magnitude-of-cold-induced-vasodilation-on-the-extremities-of-young-females
#3
Siyeon Kim, Joo-Young Lee
BACKGROUND: Menthol chemically triggers cold-sensitive receptors in the skin without conductive skin cooling. We investigated the effects of menthol-induced activation of cutaneous cold receptors on the cold-induced vasodilation (CIVD) of the finger. We hypothesized that the menthol application would attenuate typical CIVD responses. METHODS: 1.5% L-menthol was fully applied over the left hand and forearm, and then, the middle finger of the left hand was immersed into 4 °C water for 30 min...
May 9, 2018: Journal of Physiological Anthropology
https://www.readbyqxmd.com/read/29735070/in-package-atmospheric-cold-plasma-treatment-of-bulk-grape-tomatoes-for-microbiological-safety-and-preservation
#4
Sea C Min, Si Hyeon Roh, Brendan A Niemira, Glenn Boyd, Joseph E Sites, Xuetong Fan, Kimberly Sokorai, Tony Z Jin
Effects of dielectric barrier discharge atmospheric cold plasma (DACP) treatment on the inactivation of Salmonella and the storability of grape tomato were investigated. Grape tomatoes, with or without inoculation with Salmonella, were packaged in a polyethylene terephthalate (PET) commercial clamshell container and cold plasma-treated at 35 kV at 1.1 A for 3 min using a DACP system equipped with a pin-type high-voltage electrode. DACP treatment inactivated Salmonella (p < 0.05) without altering the color or firmness of the grape tomatoes (p > 0...
June 2018: Food Research International
https://www.readbyqxmd.com/read/29723621/novel-bionanocomposite-materials-used-for-packaging-skimmed-milk-acid-coagulated-cheese-karish
#5
Ahmed M Youssef, Samah M El-Sayed, Hoda S El-Sayed, Heba H Salama, Faiza M Assem, Mohamed H Abd El-Salam
Bionanocomposites have attracted a tremendous level of consideration as alternatives for a broad group of commercial materials based on petroleum-derived compounds and used for coating cheese. Sustainable, economical and environmentally compatible materials based on chitosan (CS), poly vinyl alcohol (PVA), glycerol (Gy) and titanium dioxide nanoparticles (TiO2 -NPs) were prepared. Moreover, the prepared bionanocomposites (CS/PVA/Gy/TiO2 -NPs) were characterized using XRD, SEM, TEM, WVTR and mechanical strength...
April 30, 2018: International Journal of Biological Macromolecules
https://www.readbyqxmd.com/read/29713331/optimization-of-nitrogen-phosphorus-and-potassium-fertilization-rates-for-overseeded-perennial-ryegrass-turf-on-dormant-bermudagrass-in-a-transitional-climate
#6
Muhammad Ihtisham, Shah Fahad, Tao Luo, Robert M Larkin, Shaohua Yin, Longqing Chen
Bermudagrass [ Cynodon dactylon (L.) Pers.] turf loss due to severe cold in transitional climates is a major concern. To overcome this problem, warm-season grass is often overseeded with a cool-season turfgrass. In this study, modeling and efficient nutrient management were used to evaluate this problem. A three-factor and five-level central composite rotatable design (CCRD) with a simulation of a regression model was used to optimize fertilization rates. The study investigated the combined effects of fertilization with nitrogen (N), phosphorus (P), and potassium (K) on both the morphological and physiological attributes and on the integrated turf performance (ITP) of overseeded perennial ryegrass ( Lolium perenne )...
2018: Frontiers in Plant Science
https://www.readbyqxmd.com/read/29704151/extracellular-matrix-remodeling-and-modulation-of-inflammation-and-oxidative-stress-by-sulforaphane-in-experimental-diabetic-peripheral-neuropathy
#7
Passant E Moustafa, Noha F Abdelkader, Sally A El Awdan, Osama A El-Shabrawy, Hala F Zaki
The peripheral nervous system is one of many organ systems that can be profoundly impacted in diabetes mellitus. Diabetic peripheral neuropathy has a significant negative effect on patients' quality of life as it begins with loss of limbs' sensation and may result in lower limb amputation. This investigation aimed at exploring the effect of sulforaphane on peripheral neuropathy in diabetic rats. Experimental diabetes was induced through single intraperitoneal injections of nicotinamide (50 mg/kg) and streptozotocin (52...
April 27, 2018: Inflammation
https://www.readbyqxmd.com/read/29688538/instrumental-compression-force-and-meat-attribute-changes-in-woody-broiler-breast-fillets-during-short-term-storage
#8
X Sun, D A Koltes, C N Coon, K Chen, C M Owens
Woody breast (WB) is a myopathy of the Pectoralis major muscle in broilers that is characterized by increased hardness of the raw fillet. This defect increases economic losses due to associated decreased meat quality and the addition of training skilled laborers to identify problematic fillets. Therefore, the objectives of this study were to determine if compression force (CF) could be used as a non-invasive method of detecting WB and to assess changes in meat attributes during cold storage. Deboned fillets (n = 121) were collected from 8-wk-old broilers, and categorized as normal (NORM, n = 42), mild (MILD, n = 39), and moderate/severe (SEV, n = 40) for WB...
April 23, 2018: Poultry Science
https://www.readbyqxmd.com/read/29650773/cannabinoid-type-1-receptors-are-upregulated-during-acute-activation-of-brown-adipose-tissue
#9
Minna Lahesmaa, Olof Eriksson, Thorsten Gnad, Vesa Oikonen, Marco Bucci, Jussi Hirvonen, Kalle Koskensalo, Jarmo Teuho, Tarja Niemi, Markku Taittonen, Salla Lahdenpohja, Mueez U Din, Merja Haaparanta-Solin, Alexander Pfeifer, Kirsi A Virtanen, Pirjo Nuutila
Activating brown adipose tissue (BAT) could provide a potential approach for the treatment of obesity and metabolic disease in humans. Obesity is associated with up-regulation of the endocannabinoid system, and blocking the cannabinoid type 1 receptor (CB1R) has been shown to cause weight loss and decrease cardiometabolic risk factors. These effects may partly be mediated via increased BAT metabolism, since there is evidence that CB1R antagonism activates BAT in rodents. To investigate the significance of CB1R in BAT function, we quantified the density of CB1R in human and rodent BAT using the positron emission tomography (PET) radioligand [18 F]FMPEP- d 2 , and in parallel measured BAT activation with the glucose analogue [18 F]FDG...
April 12, 2018: Diabetes
https://www.readbyqxmd.com/read/29629061/depression-from-the-perspective-of-modern-and-persian-medicine
#10
Majid Anushiravani, Ali Akhondpour Manteghi, Ali Taghipur, Mahdi Eslami
Background: Depression is one of the five most-common diseases globally, and is expected to be the second leading cause of disability by 2020 and its economic and social burden is a major problem worldwide. Objective: The aim of this research was to elucidate the causes and symptoms of depression according to Persian Medicine (PM) and classic medicine. Methods: In this study, works that were investigated were the Canon of Medicine , Al-Hawi Fi Teb , Kamel Al-Sina'a , Zakhireh Kharazmshahi and Exir A'azam ...
February 2018: Electronic Physician
https://www.readbyqxmd.com/read/29617402/carnivore-hotspots-in-peninsular-malaysia-and-their-landscape-attributes
#11
Shyamala Ratnayeke, Frank T van Manen, Gopalasamy Reuben Clements, Noor Azleen Mohd Kulaimi, Stuart P Sharp
Mammalian carnivores play a vital role in ecosystem functioning. However, they are prone to extinction because of low population densities and growth rates, and high levels of persecution or exploitation. In tropical biodiversity hotspots such as Peninsular Malaysia, rapid conversion of natural habitats threatens the persistence of this vulnerable group of animals. Here, we carried out the first comprehensive literature review on 31 carnivore species reported to occur in Peninsular Malaysia and updated their probable distribution...
2018: PloS One
https://www.readbyqxmd.com/read/29584905/effects-of-production-systems-on-the-carcass-and-meat-quality-characteristics-of-spent-laying-hens
#12
F Semwogerere, J Neethling, V Muchenje, L C Hoffman
This study evaluated the carcass characteristics and meat quality attributes of spent laying hens raised under conventional battery cage and free-range systems. Thirty free-range and 30 conventional battery-caged Lohmann Brown-Elite spent laying hens of 53 and 40 wk of age, respectively were obtained from a commercial egg producer. Carcass, portion, and organ weights and percentages were determined. Physicochemical analyses were performed on thigh and breast meat samples. Caged hens had heavier (P ≤ 0.05) warm and cold carcasses, thighs, wings, and feet...
March 22, 2018: Poultry Science
https://www.readbyqxmd.com/read/29572954/water-requirements-of-canine-athletes-during-multi-day-exercise
#13
Lara Stephens-Brown, Michael Davis
BACKGROUND: Exercise increases water requirements, but there is little information regarding water loss in dogs performing multi-day exercise OBJECTIVES: Quantify the daily water turnover of working dogs during multi-day exercise and establish the suitability of SC administration of tracer to determine water turnover. ANIMALS: Fifteen privately owned Labrador retrievers trained for explosive detection duties and 16 privately owned Alaskan Huskies conditioned for mid-distance racing...
March 23, 2018: Journal of Veterinary Internal Medicine
https://www.readbyqxmd.com/read/29572844/liraglutide-ameliorated-peripheral-neuropathy-in-diabetic-rats-involvement-of-oxidative-stress-inflammation-and-extracellular-matrix-remodeling
#14
Passant E Moustafa, Noha F Abdelkader, Sally A El Awdan, Osama A El-Shabrawy, Hala F Zaki
Diabetic peripheral neuropathy is one of the most common microvascular complications that occurs with both type 1 and type 2 diabetes mellitus. It has a significant negative impact on patients' quality of life; as it starts with loss of limbs' sensation and may lead to lower limb amputation. This study aimed at investigating the effect of liraglutide on peripheral neuropathy in diabetic rats. Experimental diabetes was induced by single intraperitoneal injections of nicotinamide (50 mg/kg) and streptozotocin (52...
March 23, 2018: Journal of Neurochemistry
https://www.readbyqxmd.com/read/29558911/aqueous-and-ethanolic-extracts-of-welsh-onion-allium-fistulosum-attenuate-high-fat-diet-induced-obesity
#15
Yoon-Young Sung, Dong-Seon Kim, Seung-Hyung Kim, Ho Kyoung Kim
BACKGROUND: Allium fistulosum (Welsh onion) is a traditional medicinal plant used for the treatment of colds, influenza, abdominal pain, headache, and heart disease. This study evaluated the effects of A. fistulosum ethanolic extract (AFE) and aqueous extract (AFW) on body weight and other obesity-related parameters. METHODS: Male 8-week-old C57BL/6 J mice were fed either a standard chow diet (normal control) or a high-fat diet (HFD) either alone (HFD-control) or in combination with G...
March 20, 2018: BMC Complementary and Alternative Medicine
https://www.readbyqxmd.com/read/29518741/fatty-acid-profile-and-carcass-traits-of-feedlot-nellore-cattle-fed-crude-glycerin-and-virginiamycin
#16
Pablo S Castagnino, Giovani Fiorentini, Erick E Dallantonia, Elias San Vito, Juliana D Messana, Juliana A Torrecilhas, Américo G Silva Sobrinho, Telma T Berchielli
Forty-eight bulls with an initial body weight (BW) of 408.4 ± 22.2 kg (age = 21 ± 2 months) were used in a randomized complete block design arranged in a 2 × 2 factorial design. The treatments were diets without virginiamycin (VM-) or with virginiamycin, at 25 mg/kg of dry matter (DM, VM+), and diets without crude glycerin (CG-) or with crude glycerin, at 100 g/kg DM (CG+). The cold carcass weight and cold carcass dressing (P ≤ 0.05) was greater in bulls fed crude glycerin diets...
June 2018: Meat Science
https://www.readbyqxmd.com/read/29505674/outcomes-of-left-split-graft-transplantation-in-europe-report-from-the-european-liver-transplant-registry
#17
Roberta Angelico, Alessandra Nardi, René Adam, Silvio Nadalin, Wojciech G Polak, Vincent Karam, Roberto I Troisi, Paolo Muiesan
Split liver transplantation (SLT) has been widely adopted across Europe, resulting in remarkable reduction in the paediatric waiting-list mortality. Left split graft (LSG) is commonly used for paediatric recipients; however, deceased donor criteria selection are not universal. The aim of this study was to analyse the LSG outcome from the European Liver Transplant Registry and to identify risk factors for graft failure. Data from 1500 children transplanted in 2006-2014 with LSG from deceased donors were retrospectively analysed...
March 5, 2018: Transplant International: Official Journal of the European Society for Organ Transplantation
https://www.readbyqxmd.com/read/29391609/cold-extraction-method-of-chia-seed-mucilage-salvia-hispanica-l-effect-on-yield-and-rheological-behavior
#18
Lucas Silveira Tavares, Luciana Affonso Junqueira, Ívina Catarina de Oliveira Guimarães, Jaime Vilela de Resende
Chia seeds ( Salvia hispanica L.) when immersed in water, produce a highly viscous solution due to the release of mucilage, high molecular weight complex carbohydrates with wide application in the food industry. Thus, this study involve development of method for extracting mucilage from chia seed based on mechanical process and low temperature. The method involve extraction by cold pressing and drying by freeze-drying, which was compared to the traditional hot extraction method. The chia seed mucilage cultivated in Brazil was extracted successfully using the previously mentioned extraction method...
February 2018: Journal of Food Science and Technology
https://www.readbyqxmd.com/read/29379898/anti-ma-1-and-anti-ma-2-antibodies-in-isolated-fatal-hypothalamitis
#19
Mario Bustos, Hara Berger, Zeina Carolina Hannoush, Alejandro Ayala, Rochelle Freire, Atil Yilmaz Kargi
Lymphocytic hypothalamitis (LHT) is a rare disease characterized by pituitary dysfunction, autonomic instability, metabolic disturbances, and neuropsychiatric disorders. We report the case of a 30-year-old man found to have LHT that progressed despite treatment with methylprednisolone and intravenous immunoglobulin (IVIG). A literature review was conducted to identify prior studies pertaining to LHT. Our patient presented with several weeks of fatigue, cold intolerance, weight loss, confusion, and headache...
February 1, 2018: Journal of the Endocrine Society
https://www.readbyqxmd.com/read/29320702/repression-of-adipose-tissue-fibrosis-through-a-prdm16-gtf2ird1-complex-improves-systemic-glucose-homeostasis
#20
Yutaka Hasegawa, Kenji Ikeda, Yong Chen, Diana L Alba, Daniel Stifler, Kosaku Shinoda, Takashi Hosono, Pema Maretich, Yangyu Yang, Yasushi Ishigaki, Jingyi Chi, Paul Cohen, Suneil K Koliwad, Shingo Kajimura
Adipose tissue fibrosis is a hallmark of malfunction that is linked to insulin resistance and type 2 diabetes; however, what regulates this process remains unclear. Here we show that the PRDM16 transcriptional complex, a dominant activator of brown/beige adipocyte development, potently represses adipose tissue fibrosis in an uncoupling protein 1 (UCP1)-independent manner. By purifying the PRDM16 complex, we identified GTF2IRD1, a member of the TFII-I family of DNA-binding proteins, as a cold-inducible transcription factor that mediates the repressive action of the PRDM16 complex on fibrosis...
January 9, 2018: Cell Metabolism
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