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Omega 3 aging

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https://www.readbyqxmd.com/read/28212390/lack-of-effects-of-fish-oil-supplementation-for-12-weeks-on-resting-metabolic-rate-and-substrate-oxidation-in-healthy-young-men-a-randomized-controlled-trial
#1
Sebastian Jannas-Vela, Kaitlin Roke, Stephanie Boville, David M Mutch, Lawrence L Spriet
: Fish oil (FO) has been shown to have beneficial effects in the body via incorporation into the membranes of many tissues. It has been proposed that omega-3 fatty acids in FO may increase whole body resting metabolic rate (RMR) and fatty acid (FA) oxidation in human subjects, but the results to date are equivocal. The purpose of this study was to investigate the effects of a 12 week FO supplementation period on RMR and substrate oxidation, in comparison to an olive oil (OO) control group, in young healthy males (n = 26; 22...
2017: PloS One
https://www.readbyqxmd.com/read/28193371/-a-brief-homophobia-scale-in-medical-students-from-two-universities-results-of-a-refinement-process
#2
Adalberto Campo-Arias, Edwin Herazo, Heidi Celina Oviedo
BACKGROUND: The process of evaluating measurement scales is an ongoing procedure that requires revisions and adaptations according to the characteristics of the participants. The Homophobia Scale of seven items (EHF-7) has showed acceptable performance in medical students attending to two universities in Colombia. However, performance of some items was poor and could be removed, with an improvement in the psychometric findings of items retained. OBJECTIVE: To review the psychometric functioning and refine the content of EHF-7 among medical students from two Colombian universities...
January 2017: Revista Colombiana de Psiquiatría
https://www.readbyqxmd.com/read/28192538/pattern-of-omega-3-polyunsaturated-fatty-acid-intake-and-fish-consumption-and-retinal-vascular-caliber-in-children-and-adolescents-a-cohort-study
#3
Bamini Gopinath, Hanieh Moshtaghian, Victoria M Flood, Jimmy C Y Louie, Gerald Liew, George Burlutsky, Paul Mitchell
We aimed to investigate whether fish and long chain omega-3 polyunsaturated fatty acid (LCn-3 PUFA) consumption changed appreciably during adolescence. We also assessed whether these dietary variables are associated with retinal microvascular signs (possible markers of future cardiovascular disease risk). 633 children had dietary data at ages 12 and 17. Fish and LCn-3 PUFA [eicosapentaenoic acid (EPA), docosapentaenoic acid (DPA) and docosahexaenoic acid (DHA)] intake was assessed by a food frequency questionnaire...
2017: PloS One
https://www.readbyqxmd.com/read/28185855/biphasic-effect-of-alpha-linolenic-acid-on-glucose-induced-dysmorphogenesis-and-lipoperoxidation-in-whole-rat-embryo-in-culture
#4
Gladys Chirino-Galindo, Jorge-Israel Barrera-Argüelles, Ninna-Leslie Trejo-González, Ricardo Mejía-Zepeda, Martín Palomar-Morales
Type 1 diabetes mellitus complicated with pregnancy, know as diabetic embryopathy, is the cause of neonatal malformations and low for gestational age neonates. With the use of the whole-embryo culture system, it has been demonstrated that high glucose causes embryo dysmorphogenesis, and that oxidative stress appears to be the main mechanism. In recent years, beneficial effect of omega-3 fatty acids has been demonstrated in various diabetic models, and in diabetic complications. Since diabetic embryopathy is mediated probably through membrane lipoperoxidation, This study was designed to find if omega-3 fatty acids could ameliorate the effect of high glucose over the dysmorphogenesis of whole rat embryo in culture...
February 6, 2017: Biochemical and Biophysical Research Communications
https://www.readbyqxmd.com/read/28183054/national-estimation-of-seafood-consumption-in-mexico-implications-for-exposure-to-methylmercury-and-polyunsaturated-fatty-acids
#5
Alejandra Cantoral, Carolina Batis, Niladri Basu
BACKGROUND: Seafood is a good source of Omega-3 polyunsaturated fatty acids (ω3-PUFA) but also contains the toxic contaminant methylmercury (MeHg). National estimates of exposure to both compounds through seafood intake in Mexico are not known. The objective of the current study was to describe national seafood consumption habits and to estimate seafood-based exposure to ω3-PUFAs and MeHg. METHODS: We analyzed data from a 24-h dietary recall extracted from the 2012 National Health and Nutrition Survey of Mexico (n = 10,096 subjects aged 1y and older)...
January 26, 2017: Chemosphere
https://www.readbyqxmd.com/read/28166924/-lifestyle-recommendations-for-prevention-of-spontaneous-preterm-birth-in-asymptomatic-pregnant-women
#6
E Maisonneuve
OBJECTIVES: To establish recommendations for lifestyle of pregnant women and its impact on spontaneous preterm births. MATERIAL AND METHODS: We searched Pubmed and Cochrane databases and checked reference lists of retrieved studies. This review of the literature concerns only women who have no symptoms for the ongoing pregnancy. RESULTS: Concerning maternal occupation during pregnancy, there is a mild increase of the risk of preterm birth only for women who work more than 40hours a week or who have hard working conditions according to a fatigue score (LE2)...
December 2016: Journal de Gynécologie, Obstétrique et Biologie de la Reproduction
https://www.readbyqxmd.com/read/28157380/omega-3-fatty-acid-plasma-levels-before-and-after-supplementation-correlations-with-mood-and-clinical-outcomes-in-the-omega-3-and-therapy-studies
#7
L Eugene Arnold, Andrea S Young, Martha A Belury, Rachel M Cole, Barbara Gracious, Adina M Seidenfeld, Hannah Wolfson, Mary A Fristad
OBJECTIVE: To examine fatty acid profiles, their response to omega-3 fatty acid (Ω3) supplementation, and associations with clinical status and treatment response in youth with mood disorders. METHODS: In a placebo-controlled 2X2 design, 7-14 year-olds (N = 95) in parallel pilot trials (depression N = 72; bipolar N = 23) were randomly assigned to 12 weeks of Ω3 supplementation (1.4 g eicosapentaenoic acid [EPA], 0.2 g docosahexaenoic acid [DHA], and 0...
February 3, 2017: Journal of Child and Adolescent Psychopharmacology
https://www.readbyqxmd.com/read/28154734/nutritional-and-lifestyle-interventions-for-age-related-macular-degeneration-a-review
#8
REVIEW
Ângela Carneiro, José Paulo Andrade
Age-related macular degeneration (AMD) is the leading cause of blindness in the developed world. In this narrative review, we will summarize the nutritional interventions evaluated in numerous observational studies and a few randomized clinical trials. The AREDS and AREDS2 studies demonstrated that supplements including vitamins C and E, beta-carotene, and zinc may reduce the progression to advanced AMD, in some patients, by 25% in five years. This is one of the few nutritional supplements known to have beneficial effects in any eye disease...
2017: Oxidative Medicine and Cellular Longevity
https://www.readbyqxmd.com/read/28153504/effect-of-omega-3-polyunsaturated-fatty-acids-derived-from-fish-oil-in-major-burn-patients-a-prospective-randomized-controlled-pilot-trial
#9
Serrana Tihista, Estrella Echavarría
BACKGROUND & AIMS: The burn patient is the clearest example of prolonged inflammatory response. Various nutrients, particularly omega-3 polyunsaturated fatty acids (ω-3 PUFAs), have been demonstrated as attenuating the inflammatory response, and reduce infectious complications. In absence of definitive evidence in major burns the study aimed at investigating the effect particularly on infectious complications of enteral nutrition enriched with ω-3 PUFAs. METHOD: Prospectively randomized controlled trial...
January 16, 2017: Clinical Nutrition: Official Journal of the European Society of Parenteral and Enteral Nutrition
https://www.readbyqxmd.com/read/28144165/osteosarcopenic-obesity-in-women-impact-prevalence-and-management-challenges
#10
REVIEW
Pegah JafariNasabian, Julia E Inglis, Owen J Kelly, Jasminka Z Ilich
Osteosarcopenic obesity syndrome (OSO) has recently been identified as a condition encompassing osteopenia/osteoporosis, sarcopenia and obesity. OSO is especially deleterious in older adults (even if they are not obese by conventional measures), due to age-related redistribution of fat and its infiltration into bone and muscle. Osteoporosis and bone fractures in elderly increase the risk of sarcopenia, which, through decreased mobility, increases the risk of more falls and fractures, creating a vicious cycle...
2017: International Journal of Women's Health
https://www.readbyqxmd.com/read/28141545/the-effect-of-fish-oil-supplementation-on-maternal-and-neonatal-outcomes-a-triple-blind-randomized-controlled-trial
#11
Alireza Ostadrahimi, Sakineh Mohammad-Alizadeh, Mojgan Mirghafourvand, Shadi Farshbaf-Khalili, Nayyer Jafarilar-Agdam, Azizeh Farshbaf-Khalili
OBJECTIVE: To evaluate the effect of fish oil supplementation on pregnancy outcomes in mother and newborn. METHODS: This randomized, triple-blind, placebo-controlled trial was conducted on 150 pregnant women aged 18-35 years from Feburary 2014 to April 2015 in Tabriz, Iran. Participants were assigned to receive either 1000 mg fish oil supplements containing 180 mg eicosapentaenoic acid (EPA) and 120 mg docosahexanoic acid or placebo from week 20 of gestation to birth...
January 31, 2017: Journal of Perinatal Medicine
https://www.readbyqxmd.com/read/28126360/effects-of-omega-3-pufa-on-immune-markers-in-adolescent-individuals-at-ultra-high-risk-for-psychosis-results-of-the-randomized-controlled-vienna-omega-3-study
#12
Stefan Smesny, Berko Milleit, Miriam R Schaefer, Jana Hesse, Monika Schlögelhofer, Kerstin Langbein, Uta-Christina Hipler, Maximus Berger, David R Cotter, Heinrich Sauer, Patrick D McGorry, G Paul Amminger
Alterations of immune function have been reported in ultra-high risk (UHR) for psychosis patients causing expectations in terms of predictive meaningfulness and benefits of anti-inflammatory agents. According to a RCT in UHR-patients supplementation of omega-3 polyunsaturated fatty acids (PUFA) was effective in reducing transition to psychosis risk and to improve symptomatology. Based on preclinical findings, we now investigated state marker properties of and the influence of PUFA on immune markers in a RCT (clinical trials...
January 23, 2017: Schizophrenia Research
https://www.readbyqxmd.com/read/28106665/effects-of-multielectrode-renal-denervation-on-elevated-sympathetic-nerve-activity-and-insulin-resistance-in-metabolic-syndrome
#13
Costas Tsioufis, Kyriakos Dimitriadis, Alexandros Kasiakogias, Theodore Kalos, Ioannis Liatakis, Evagelia Koutra, Levki Nikolopoulou, Athanasios Kordalis, Rita Omega Ella, Elizabeth Oi-Yan Lau, Guido Grassi, Vasilios Papademetriou, Dimitrios Tousoulis
OBJECTIVE: This study aimed to investigate the effects of renal denervation (RDN) on sympathetic nerve activity and insulin resistance in patients with metabolic syndrome. METHODS: Seventeen patients fulfilled at least four of five criteria for metabolic syndrome and under stable use of at least two antihypertensive drugs were randomized in 3 : 1 ratio to RDN (n = 13, 12 men, age: 58 ± 7 years) and control groups (n = 4, three men, age: 60 ± 5 years) and followed up for 3 months...
January 18, 2017: Journal of Hypertension
https://www.readbyqxmd.com/read/28104914/docosahexaenoic-acid-mediated-protein-aggregates-may-reduce-proteasome-activity-and-delay-myotube-degradation-during-muscle-atrophy-in-vitro
#14
Seung Kyun Shin, Ji Hyeon Kim, Jung Hoon Lee, Young Hoon Son, Min Wook Lee, Hak Joong Kim, Sue Ah Noh, Kwang Pyo Kim, In-Gyu Kim, Min Jae Lee
Proteasomes are the primary degradation machinery for oxidatively damaged proteins that compose a class of misfolded protein substrates. Cellular levels of reactive oxygen species increase with age and this cellular propensity is particularly harmful when combined with the age-associated development of various human disorders including cancer, neurodegenerative disease and muscle atrophy. Proteasome activity is reportedly downregulated in these disease conditions. Herein, we report that docosahexaenoic acid (DHA), a major dietary omega-3 polyunsaturated fatty acid, mediates intermolecular protein cross-linkages through oxidation, and the resulting protein aggregates potently reduce proteasomal activity both in vitro and in cultured cells...
January 20, 2017: Experimental & Molecular Medicine
https://www.readbyqxmd.com/read/28056448/dietary-predictors-and-plasma-concentrations-of-perfluorinated-alkyl-acids-in-a-singapore-population
#15
Yu Liu, Jin Su, Rob M van Dam, Kiesha Prem, Joey Y S Hoong, Li Zou, Yonghai Lu, Choon Nam Ong
Perfluorinated alkyl acids (PFAAs), a family of man-made organofluorinated compounds, have drawn much attention due to their ubiquitous existence in the environment and their bioaccumulation potential. Here, we examined the plasma concentrations of thirteen PFAAs in a healthy population (N = 270) in Singapore, and investigated the association between major food groups and plasma PFAA concentrations. We detected eight types of PFAAs in more than 75% of all samples (N = 270), and their median concentrations ranged from 0...
December 26, 2016: Chemosphere
https://www.readbyqxmd.com/read/28055065/effect-of-fish-oil-supplementation-and-aspirin-use-on-arteriovenous-fistula-failure-in-patients-requiring-hemodialysis-a-randomized-clinical-trial
#16
Ashley B Irish, Andrea K Viecelli, Carmel M Hawley, Lai-Seong Hooi, Elaine M Pascoe, Peta-Anne Paul-Brent, Sunil V Badve, Trevor A Mori, Alan Cass, Peter G Kerr, David Voss, Loke-Meng Ong, Kevan R Polkinghorne
Importance: Vascular access dysfunction is a leading cause of morbidity and mortality in patients requiring hemodialysis. Arteriovenous fistulae are preferred over synthetic grafts and central venous catheters due to superior long-term outcomes and lower health care costs, but increasing their use is limited by early thrombosis and maturation failure. ω-3 Polyunsaturated fatty acids (fish oils) have pleiotropic effects on vascular biology and inflammation and aspirin impairs platelet aggregation, which may reduce access failure...
February 1, 2017: JAMA Internal Medicine
https://www.readbyqxmd.com/read/28048960/impact-of-environment-and-ontogeny-on-relative-fecundity-and-egg-quality-of-female-oysters-crassostrea-virginica-from-four-sites-in-northern-chesapeake-bay
#17
Hillary Lane Glandon, Adriane K Michaelis, Vincent A Politano, Stephanie T Alexander, Emily A Vlahovich, Kimberly S Reece, Heather N Koopman, Donald W Meritt, Kennedy T Paynter
Resource allocation to reproduction is a primary physiological concern for individuals, and can vary with age, environment, or a combination of both factors. In this study we quantified the impact of environment and individual age on the reproductive output of female oysters Crassostrea virginica. We determined the relative fecundity, egg total lipid content, and overall and omega-3/omega-6 (ω3/ω6) fatty acid signatures (FAS) of eggs spawned by female oysters over a 2-year period (n = 32 and n = 64). Variation was quantified spatially and ontogenetically by sampling young and old oyster populations from two rivers in Chesapeake Bay, totaling four collection sites...
December 2016: Biological Bulletin
https://www.readbyqxmd.com/read/28032469/association-between-omega-3-fatty-acids-consumption-and-the-risk-of-type-2-diabetes-a-meta-analysis-of-cohort-studies
#18
Cai Chen, Yan Yang, Xuefeng Yu, Shuhong Hu, Shiying Shao
AIMS/INTRODUCTION: Epidemiologic evidences for the effect of omega 3 fatty acids on the risk of type 2 diabetes (T2D) are controversial. A meta-analysis based on prospective cohorts was conducted to evaluate this issue. MATERIALS AND METHODS: Pooled diabetic risk was calculated using fixed or random effects model. Dose-response relationship was assessed by meta-regression analysis. RESULTS: Our study revealed that consumption of single omega-3 was associated with an increased risk of T2D (Relative Risk, RR=1...
December 29, 2016: Journal of Diabetes Investigation
https://www.readbyqxmd.com/read/28027634/dietary-optimisation-with-omega-3-and-omega-6-fatty-acids-for-12-23-month-old-overweight-and-obese-children-in-urban-jakarta
#19
Fitrianna Cahyaningrum, Inge Permadhi, Muhammad Ridwan Ansari, Erfi Prafiantini, Purnawati Hustina Rachman, Rina Agustina
BACKGROUND AND OBJECTIVES: Diets with a specific omega-6/omega-3 fatty acid ratio have been reported to have favourable effects in controlling obesity in adults. However, development a local-based diet by considering the ratio of these fatty acids for improving the nutritional status of overweight and obese children is lacking. Therefore, using linear programming, we developed an affordable optimised diet focusing on the ratio of omega- 6/omega-3 fatty acid intake for obese children aged 12-23 months...
December 2016: Asia Pacific Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/28017488/complementary-and-alternative-medicine-in-the-school-age-child-with-autism
#20
Debdeep Nath
This case study examines some common complementary and alternative treatments used in the management of behavioral and gastrointestinal symptoms associated with autism including food selectivity, abdominal pain, nausea, gastroesophageal reflux, constipation, and diarrhea. The current literature on the safety and efficacy of these treatments for pediatric patients is reviewed. This study examines therapies including gluten-free and casein-free diet, probiotics, vitamin B12, omega-3 fatty acid supplementation, chelation therapy, acupuncture, and chiropractic manipulations used in treating these core symptoms of autism...
December 22, 2016: Journal of Pediatric Health Care
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