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Bipolar review

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https://www.readbyqxmd.com/read/28078988/bdnf-nf-kb-signaling-in-the-neurobiology-of-depression
#1
Ariel Caviedes, Carlos Lafourcade, Claudio Soto, Ursula Wyneken
BACKGROUND: Mood disorders, consisting of unipolar and bipolar depression, are complex diseases characterized by depressed mood and anhedonia. These core symptoms are accompanied in a varying manner by anxiety, several neurovegetative symptoms and cognitive impairment. Mood disorders are characterized by decreases in neurogenesis, alteration in synaptic structure and synaptic transmission, all of them regulated by BDNF, a neurotrophin that performs multiple functions in the adult central nervous system...
January 11, 2017: Current Pharmaceutical Design
https://www.readbyqxmd.com/read/28077190/measures-of-the-dsm-5-mixed-features-specifier-of-major-depressive-disorder
#2
Mark Zimmerman
During the past two decades, a number of studies have found that depressed patients frequently have manic symptoms intermixed with depressive symptoms. While the frequency of mixed syndromes are more common in bipolar than in unipolar depressives, mixed states are also common in patients with major depressive disorder. The admixture of symptoms may be evident when depressed patients present for treatment, or they may emerge during ongoing treatment. In some patients, treatment with antidepressant medication might precipitate the emergence of mixed states...
January 12, 2017: CNS Spectrums
https://www.readbyqxmd.com/read/28075410/is-toxoplasma-gondii-a-trigger-of-bipolar-disorder
#3
REVIEW
Claudia Del Grande, Luca Galli, Elisa Schiavi, Liliana Dell'Osso, Fabrizio Bruschi
Toxoplasma gondii, a ubiquitous intracellular parasite, has a strong tropism for the brain tissue, where it forms intracellular cysts within the neurons and glial cells, establishing a chronic infection. Although latent toxoplasmosis is generally assumed to be asymptomatic in immunocompetent individuals, it is now clear that it can induce behavioral manipulations in mice and infected humans. Moreover, a strong relation has emerged in recent years between toxoplasmosis and psychiatric disorders. The link between T...
January 10, 2017: Pathogens
https://www.readbyqxmd.com/read/28075154/survivorship-after-meniscal-allograft-transplantation-according-to-articular-cartilage-status
#4
Bum-Sik Lee, Seong-Il Bin, Jong-Min Kim, Won-Kyeong Kim, Jun Weon Choi
BACKGROUND: Clinical outcomes after meniscal allograft transplantation (MAT) in arthritic knees are unclear, and objective estimates of graft survival according to the articular cartilage status have not been performed. HYPOTHESIS: MAT should provide clinical benefits in knees with high-grade cartilage damage, but their graft survivorship should be inferior to that in knees with low-grade chondral degeneration after MAT. STUDY DESIGN: Cohort study; Level of evidence, 3...
January 1, 2017: American Journal of Sports Medicine
https://www.readbyqxmd.com/read/28073032/diabetes-mellitus-and-first-episode-mania-associated-with-cardiovascular-diseases-in-patients-with-older-age-bipolar-disorder
#5
Pao-Huan Chen, Chi-Kang Chang, Shuo-Ju Chiang, Yen-Kuang Lin, Shang-Ying Tsai, Shou-Hung Huang
Patients with bipolar disorder (BD) are at high risk for developing cardiovascular diseases (CVDs) during aging process. However, investigations are lacking regarding the risk factors for CVDs specific to BD patients. The aim of this study was to examine the relationship between CVDs and traditional risk factors in association with the characteristics of BD in older age. Totally, we recruited 124 patients with BD-I (DSM-IV) who had at least one psychiatric admission and cardiologist-confirmed CVD diagnosis (ICD-9 code 401-414) at mean age of 61...
January 2, 2017: Psychiatry Research
https://www.readbyqxmd.com/read/28070258/a-scientific-correlation-between-dystemprament-in-unani-medicine-and-diseases-a-systematic-review
#6
REVIEW
Sepideh Miraj, Sara Kiani
BACKGROUND: Temperament or mezaj refers to four different humors differentiating in individuals and, as a result, proposes specific therapy for their diseases. OBJECTIVE: The aim of this study was to overview the scientific correlation between temperaments in Unani medicine and diseases. METHODS: This study was carried out from March 2015 to February 2016. A computerized search of published articles was performed using PubMed, Google Scholar, Scopus and Web of Science, and Medline databases as well as local and regional resources between 1983 and 2014...
November 2016: Electronic Physician
https://www.readbyqxmd.com/read/28069274/extended-bipolar-left-ventricular-pacing-as-a-possible-therapy-for-late-electrical-storm-induced-by-cardiac-resynchronization-therapy
#7
Dimitrios Asvestas, Richard Balasubramaniam, Mark Sopher, John Paisey, Girish G Babu
Although cardiac resynchronization therapy (CRT) has become a well-established treatment option for patients with drug-refractory severe systolic heart failure, there has been some evidence of adverse proarrhythmic events. We report a case of a patient with ischemic cardiomyopathy who underwent CRT with a defibrillator for primary prevention of sudden cardiac death. Two years after the implantation, the patient presented with electrical storm, which was completely terminated by modifying the left ventricular (LV) pacing configuration from true to extended bipolar LV pacing...
December 30, 2016: Journal of Electrocardiology
https://www.readbyqxmd.com/read/28068832/book-review-finding-sanity-john-cade-lithium-and-the-taming-of-bipolar-disorder-de-moore-greg-westmore-ann-allen-and-unwin-sydney
#8
Richard T White
No abstract text is available yet for this article.
January 1, 2017: Australasian Psychiatry: Bulletin of Royal Australian and New Zealand College of Psychiatrists
https://www.readbyqxmd.com/read/28066002/management-of-obsessive-compulsive-disorder-comorbid-with-bipolar-disorder
#9
REVIEW
Firoz Kazhungil, E Mohandas
Obsessive-compulsive disorder (OCD) is one of the most common comorbidities in bipolar disorder (BD). Clinicians often get perplexed in making treatment decisions when encountering comorbid OCD and BD as treatment of OCD by pharmacotherapy may induce or exacerbate mood instability and psychotherapeutic approaches for OCD may not be feasible in acute manic or depressive state of BD. In this study, we reviewed literature, whether existing guideline-based treatments of BD may be effective in OCD and whether newer agents will be of use for treating this comorbidity...
July 2016: Indian Journal of Psychiatry
https://www.readbyqxmd.com/read/28064463/global-research-trends-in-lithium-toxicity-from-1913-to-2015-a-bibliometric-analysis
#10
Sa'ed H Zyoud, W Stephen Waring, Waleed M Sweileh, Samah W Al-Jabi
Lithium salts have been used to treat psychiatric disorders since the 1940s and are currently used in prophylaxis and treatment of depression and bipolar disorder. Therefore, we conducted this study to assess lithium toxicity-related publications using bibliometric approaches from a health point of view to assess global research trends in the lithium toxicity field to offer guidance to future research in this field. The data were retrieved from the online version of Scopus database on 6 August 2016. All records with the term "lithium" in the title were retrieved, and those related to lithium toxicity were evaluated...
January 8, 2017: Basic & Clinical Pharmacology & Toxicology
https://www.readbyqxmd.com/read/28064060/a-current-view-on-contactin-4-5-and-6-implications-in-neurodevelopmental-disorders
#11
REVIEW
Oguro-Ando Asami, Amila Zuko, Kristel T E Kleijer, J Peter H Burbach
Contactins (Cntns) are a six-member subgroup of the immunoglobulin cell adhesion molecule superfamily (IgCAMs) with pronounced brain expression and function. Recent genetic studies of neuropsychiatric disorders have pinpointed contactin-4 (CNTN4), contactin-5 (CNTN5) and contactin-6 (CNTN6) as candidate genes in neurodevelopmental disorders, particularly in autism spectrum disorders (ASDs), but also in intellectual disability, schizophrenia (SCZ), attention-deficit hyperactivity disorder (ADHD), bipolar disorder (BD), alcohol use disorder (AUD) and anorexia nervosa (AN)...
January 4, 2017: Molecular and Cellular Neurosciences
https://www.readbyqxmd.com/read/28063940/linking-lipid-peroxidation-and-neuropsychiatric-disorders-focus-on-4-hydroxy-2-nonenal
#12
REVIEW
Adele Romano, Gaetano Serviddio, Silvio Calcagnini, Rosanna Villani, Anna Maria Giudetti, Tommaso Cassano, Silvana Gaetani
4-hydroxy-2-nonenal (HNE) is considered to be a strong marker of oxidative stress; the interaction between HNE and cellular proteins leads to the formation of HNE-protein adducts able to alter cellular homeostasis and cause the development of a pathological state. By virtue of its high lipid concentration, oxygen utilization, and the presence of metal ions participating to redox reactions, the brain is highly susceptible to the formation of free radicals and HNE-related compounds. A variety of neuropsychiatric disorders have been associated with elevations of HNE concentration...
January 4, 2017: Free Radical Biology & Medicine
https://www.readbyqxmd.com/read/28063207/lithiumeter-version-2-0
#13
Gin S Malhi, Samuel Gershon, Tim Outhred
BACKGROUND: The Lithiumeter was developed as a visual and practical guide for determining lithium levels in the management of bipolar disorder (BD). It appears to have been well received, as evidenced by its increasing popularity amongst doctors as a deskside clinical aide, and adoption and reproduction of the schematic in clinical guidelines and texts. However, since its publication 5 years ago, key basic neuroscience and clinical research developments pertaining to lithium have significantly advanced our understanding, necessitating further refinement of guidance concerning the practicalities of lithium therapy...
December 2016: Bipolar Disorders
https://www.readbyqxmd.com/read/28049620/how-do-people-experiencing-schizophrenia-spectrum-disorders-or-other-psychotic-disorders-use-the-internet-to-get-information-on-their-mental-health-literature-review-and-recommendations
#14
Murielle Villani, Viviane Kovess-Masfety
BACKGROUND: Studies show that the Internet has become an influential source of information for people experiencing serious psychiatric conditions such as schizophrenia spectrum disorders or other psychotic disorders, among which the rate of Internet users is growing, with rates ranging from 33.3% to 79.5% given the country. Between 20.5% and 56.4% of these Internet users seek mental health information. OBJECTIVE: Focusing on this population's Web searches about their mental health, this paper examines what type of content they look for and what could be the benefits and disadvantages of this navigation...
January 3, 2017: JMIR Mental Health
https://www.readbyqxmd.com/read/28049441/psychiatric-readmissions-and-their-association-with-physical-comorbidity-a-systematic-literature-review
#15
Lilijana Šprah, Mojca Zvezdana Dernovšek, Kristian Wahlbeck, Peija Haaramo
BACKGROUND: Comorbidity between mental and physical disorder conditions is the rule rather than the exception. It is estimated that 25% of adult population have mental health condition and 68% of them suffer from comorbid medical condition. Readmission rates in psychiatric patients are high and we still lack understanding potential predictors of recidivism. Physical comorbidity could be one of important risk factors for psychiatric readmission. The aim of the present study was to review the impact of physical comorbidity variables on readmission after discharge from psychiatric or general inpatient care among patients with co-occurring psychiatric and medical conditions...
January 3, 2017: BMC Psychiatry
https://www.readbyqxmd.com/read/28040657/neuropsychological-profiles-of-major-depressive-disorder-and-bipolar-disorder-during-euthymia-a-systematic-literature-review-of-comparative-studies
#16
REVIEW
Alejandro G Szmulewicz, Marina P Valerio, José M Smith, Cecilia Samamé, Diego J Martino, Sergio A Strejilevich
Bipolar disorder and major depressive disorder have been shown to be associated with neurocognitive abnormalities during periods of clinical remission. However, at present, there is no consensus on whether these disorders have distinctive cognitive profiles. The aim of this study was to provide an updated systematic review of studies comparing neuropsychological functioning between bipolar disorder and major depressive disorder during remission. Main findings included the following: 1) no differences regarding performances in measures of attention and processing speed, executive functions and theory of mind were found between both patient groups and 2) regarding verbal memory, preliminary evidence points towards a more defective performance in patients with bipolar disorder than those with major depressive disorder...
December 24, 2016: Psychiatry Research
https://www.readbyqxmd.com/read/28017494/formal-thought-disorder-in-schizophrenia-and-bipolar-disorder-a-systematic-review-and-meta-analysis
#17
REVIEW
Berna Yalincetin, Emre Bora, Tolga Binbay, Halis Ulas, Berna Binnur Akdede, Koksal Alptekin
Historically, formal thought disorder has been considered as one of the distinctive symptoms of schizophrenia. However, research in last few decades suggested that there is a considerable clinical and neurobiological overlap between schizophrenia and bipolar disorder (BP). We conducted a meta-analysis of studies comparing positive (PTD) and negative formal thought disorder (NTD) in schizophrenia and BP. We included 19 studies comparing 715 schizophrenia and 474 BP patients. In the acute inpatient samples, there was no significant difference in the severity of PTD (d=-0...
December 22, 2016: Schizophrenia Research
https://www.readbyqxmd.com/read/28011097/hemostasis-during-ovarian-cystectomy-a-systematic-review-of-the-impact-of-suturing-versus-surgical-energy-on-ovarian-function
#18
REVIEW
Ann Peters, Noah B Rindos, Ted Lee
This systematic review compares the effect of suturing and surgical energy utilized for hemostasis during ovarian cystectomies on ovarian function. A search of the Scopus, Embase, and PubMed databases was conducted through December 1(st) 2016 for prospective and retrospective trials as well as Randomized Controlled Trials (RCTs) that analyzed ovarian function following ovarian cystectomies where hemostasis was obtained using suturing vs. surgical energy. Of the twenty-five studies identified, twelve studies, with a total of 1,133 subjects, met the criteria and were included in this review...
December 21, 2016: Journal of Minimally Invasive Gynecology
https://www.readbyqxmd.com/read/28005435/is-there-a-weight-neutral-second-generation-antipsychotic-for-bipolar-disorder
#19
Fang Fang, Zuowei Wang, Renrong Wu, Joseph R Calabrese, Keming Gao
Antipsychotic-induced weight gain (WG) and metabolic abnormalities are major concerns. This review was untaken to answer if there is a weight-neutral second-generation antipsychotic for bipolar disorder (BPD). Areas covered: English-language literature in MEDLINE was searched with the keywords of antipsychotic/second-generation antipsychotic or generic/brand name of second-generation antipsychotic, and BPD/mania/depression or bipolar maintenance, and safety/tolerability or WG/weight increase, and randomized, placebo-controlled trial...
January 2, 2017: Expert Review of Neurotherapeutics
https://www.readbyqxmd.com/read/28004626/treating-mixed-mania-hypomania-a-review-and-synthesis-of-the-evidence
#20
Minoru Takeshima
The DSM-5 incorporates a broad concept of mixed states and captured ≥3 nonoverlapping symptoms of the opposite polarity using a "with mixed features" specifier to be applied to manic/hypomanic and major depressive episodes. Pharmacotherapy of mixed states is challenging because of the necessity to treat both manic/hypomanic and depressive symptoms concurrently. High-potency antipsychotics used to treat manic symptoms and antidepressants can potentially deteriorate symptoms of the opposite polarity. This review aimed to provide a synthesis of the current evidence for pharmacotherapy of mixed states with an emphasis on mixed mania/hypomania...
December 22, 2016: CNS Spectrums
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