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Cervical insufficiency

Jeongok Park, HeesSook Kim, Wonhee Yang, HaeWon Lee, Sang Min Park
North Korean defectors (NKD) have many health problems related to insufficient nutrition, trauma from escaping, and being exposed to infectious diseases, but little research exists on their cancer screening. A total of 638 NKD participated in this cross-sectional survey. South Korean natives (SKN) who participated in the Korean National Health and Nutrition Examination Survey V were selected using age matching to each NKD. Fisher's exact tests and logistic regression were used for data analysis. The cervical cancer screening rate of NKD was significantly lower than for SKN (42 and 70 %, respectively; P < ...
October 13, 2016: Journal of Immigrant and Minority Health
Joël Ladner, Marie-Hélène Besson, Etienne Audureau, Mariana Rodrigues, Joseph Saba
BACKGROUND: Cervical cancer is the greatest cause of age-weighted years of life lost in the developing world. Human papillomavirus (HPV) infection is associated with a high proportion of cervical cancers, and HPV vaccination may help to reduce the incidence of cancer. The aim of the study was to identify barriers, obstacles, and strategies and to analyze key concerns and lessons learned with respect to the implementation of HPV vaccination program in low- and middle-income countries. METHODS: The Gardasil Access Program (GAP) is a donation program established to enable organizations and institutions in eligible low-resource countries to gain operational experience designing and implementing HPV vaccination programs...
October 13, 2016: BMC Health Services Research
Jonathan H Rapp, Meggie Yuen, Teena Abraham
PURPOSE: There have been 3 published reports (4 cases) of symptomatic sinus bradycardia occurring after intravenous (IV) administration of the selective 5-hydroxytryptamine 3 (5-HT3) receptor antagonist ondansetron. We report a fifth case in which the patient developed asystole after rechallenge with ondansetron. SUMMARY: A 36-year-old pregnant patient with no cardiac history, status post cerclage for cervical insufficiency, experienced nausea in the post ambulatory care unit after administration of morphine and indomethacin for pain...
November 2015: Hospital Pharmacy
Veronika Holubeková, Andrea Mendelová, Marián Grendár, Sandra Meršaková, Ivana Kapustová, Karin Jašek, Andrea Vaňochová, Jan Danko, Zora Lasabová
Cervical cancer is the fourth leading cause of cancer mortality in females worldwide. Infection with high-risk human papillomavirus (HPV) is essential but insufficient to cause cervical cancer, and the clearance of HPV infection is mediated by the immune system. The deficit of molecules responsible for adhesion may play a role in the development of cervical cancer. E-cadherin is encoded by the cadherin 1 (CDH1) gene, and is involved in cell adhesion by forming adherens junctions. The aim of present study was to investigate the methylation pattern of the CDH1 promoter and to identify the association between CDH1 promoter hypermethylation, CDH1 gene expression and HPV infection in cervical specimens obtained from 93 patients with low-grade squamous intraepithelial lesions (SILs), high-grade SILs or squamous cell carcinomas, and from 47 patients with normal cervical cytology (HPV-negative)...
October 2016: Oncology Letters
Mahira Jahic, Elmir Jahic
BACKGROUND: Atypical squamous cells of undetermined significance (ASCUS) is a term that refers to inflammatory, reactive and reparative processes which are atypical and of higher level and insufficient to be classified as cervical intraepithelial lesions (CIN). AIMS: Examine of frequency of HPV infection in ASCUS lesions and regression, stagnation and progression during six-month period. SUBJECTS AND METHODS: Prospective study was conducted over a period of 3 years...
July 27, 2016: Medical Archives
Sheikh Asad, Idrees Sher, Jens Peters-Willke, Peter Jessup
Neurotropic melanoma (NM) is a rare variant of cutaneous melanomas. Compared with conventional melanoma, NM is more locally aggressive with an increased tendency for local recurrence but less likely for nodal or distant metastases. The often amelanotic, benign appearance may lead to treatment issues such as late presentation, diagnostic delay, misdiagnosis, insufficient surgical margins, and recurrence with resulting poor outcome. To our knowledge, this is the first case report of NM with contiguous spread to the spinal cord...
March 2016: J Spine Surg
Ricardo Duarte, Michel Mesnard, Philippe Wentzy, Mathieu De Sèze
OBJECTIVE: Camptocormia is a postural disease characterized by the trunk's antero-flexion during the walking gait. A brace to correct the posture is usually proposed. The evaluation of its effect through static measures has proved to be insufficient. The brace effectiveness was never evaluated on the kinematics point of view. According to that, the purpose of this study was to evaluate cinematically the evolution of the cervical arrow during the walking gait in patients with camptocormia...
September 2016: Annals of Physical and Rehabilitation Medicine
H Tanaka, A Kato, M Kawaguchi, T Yamaguchi, M Kitahara, K Matsuyama, S Okada, M Matsuo
No abstract text is available yet for this article.
October 1, 2016: International Journal of Radiation Oncology, Biology, Physics
Kirstine Sneider, Ole Bjarne Christiansen, Iben Blaabjerg Sundtoft, Jens Langhoff-Roos
INTRODUCTION: The objective was to describe recurrence rates of second trimester miscarriage and extreme preterm delivery by phenotype and use of prophylactic cerclage in a register-based cohort. MATERIAL AND METHODS: We included women with a first second trimester miscarriage or extreme preterm delivery (16(+0) - 27(+6) gestational weeks) in Denmark in 1997-2012 (n=9602) by combined use of the Danish Medical Birth Register and the Danish National Patient Register...
September 24, 2016: Acta Obstetricia et Gynecologica Scandinavica
Eun Young Jung, Kyung Joon Oh, Joon-Seok Hong, Bo Ryoung Han, Jung Kyung Joo
AIM: The aim of this study was to assess the effect of vaginal progesterone as an adjuvant therapy to physical-exam-indicated cervical cerclage (PEICC). METHODS: This retrospective cohort study included 53 consecutive singleton women who underwent PEICC because of acute cervical insufficiency at 17-24 gestational weeks. The study population was divided into two groups: the adjuvant progesterone group (n = 18) and the non-adjuvant group (n = 35). A 200-mg dose of vaginal micronized natural progesterone was administered after cerclage in the adjuvant progesterone group...
September 19, 2016: Journal of Obstetrics and Gynaecology Research
D Schmidt
The correlation between the cytological findings from the PAP smear and the histological outcome in cases where the cytological findings must be histologically verified, is an integral component of the German screening program for cervical cancer. These data are collected nationwide as part of a benchmarking process by the individual Associations of Statutory Health Insurance Physicians (KV) in the federal states and reported to the National Association of Statutory Health Insurance Physicians (KBV) in Berlin...
September 15, 2016: Der Pathologe
A A Chernyavsky, N A Lavrov
AIM: to present treatment of patients with gastroesophageal cancer. MATERIAL AND METHODS: 41 cases of esophagogastrectomy with simultaneous intestinal repair were analyzed. There were 37 operations for malignancies and 4 operations for benign diseases. Indications for surgery were defined. Abdominocervical access was predominantly used. In 6 patients esophageal repair was finished by high intrapleural anastomosis due to insufficient length of the graft for cervical anastomosis...
2016: Khirurgiia
Luchin F Wong, Jacob Wilkes, Kent Korgenski, Michael W Varner, Tracy A Manuck
OBJECTIVE: The objective of this study was to describe pregnancy outcomes, including cervical insufficiency and preterm birth, in the subsequent pregnancy following an intrapartum cervical laceration. STUDY DESIGN: Retrospective cohort of women with their first two consecutive singleton pregnancies carried to ≥ 20(0/7) weeks' gestation within a tertiary health care system from 2002 to 2012. Cervical laceration cases were identified by ICD9 codes and included if suture repair was required...
July 2016: American Journal of Perinatology Reports
Guangxin Duan, Jiaping Xu, Jijun Shi, Yongjun Cao
Bow hunter's syndrome (BHS), also known as rotational vertebral artery (VA) occlusion syndrome, is a rare yet treatable type of symptomatic vertebrobasilar insufficiency resulting from mechanical occlusion or stenosis of the VA during head and neck rotation or extension. The symptoms of BHS range from transient vertigo to posterior circulation stroke. The underlying pathology is dynamic stenosis or compression of the VA by abnormal bony structures with neck rotation or extension in many cases, such as osteophyte, disc herniation, cervical spondylosis, tendinous bands or tumors...
June 2016: Interventional Neurology
Daniel R Felbaum, Joshua E Ryan, Andrew B Stemer, Amjad N Anaizi
Rotational vertebral artery occlusion (RVAO) or bow hunter's syndrome most commonly affects the C1-2 level due to its importance in regulating rotational movement. We present a 50-year old man who had undergone several prior sub-axial cervical spine operations with increasing neck pain and severe symptoms of vertebrobasilar insufficiency with bi-directional head rotation. Dynamic cerebral angiography demonstrated complete occlusion of left vertebral artery during head rotation to the right, and complete occlusion of the right vertebral artery during head rotation to the left...
September 5, 2016: World Neurosurgery
Lameck Chinula, Agnes Moses, Satish Gopal
PURPOSE OF REVIEW: To summarize recent developments for HIV-associated malignancies (HIVAM) in low-income and middle-income countries (LMIC) with particular focus on sub-Saharan Africa (SSA). RECENT FINDINGS: Antiretroviral therapy (ART) scale-up is leading to epidemiologic transitions in LMIC similar to high-income countries, with aging and growth of HIV-infected populations, declining infectious deaths, increasing cancer deaths, and transitions from AIDS-defining cancers to non-AIDS defining cancers...
September 7, 2016: Current Opinion in HIV and AIDS
Rob A B Oostendorp, Hans Elvers, Emilia Mikolajewska, Nathalie Roussel, Emiel van Trijffel, Han Samwel, Jo Nijs, William Duquet
OBJECTIVES: The term 'cephalalgiaphobia' was introduced in the mid-1980s and defined as fear of migraine (attacks). We hypothesized that a specific subtype of cephalalgiaphobia affects patients with cervicogenic headache (CEH). This study aimed to: (1) define the term 'cervico-cephalalgiaphobia'; (2) develop a set of indicators for phobia relevant to patients with CEH; and (3) apply this set to a practice test in order to estimate the frequency of cervico-cephalalgiaphobia in the Dutch primary care practice of manual physical therapy...
September 2016: Journal of Manual & Manipulative Therapy
Mougnyan Cox, Bryan Pukenas, Michael Poplawski, Aaron Bress, Diane Deely, Adam Flanders
RATIONALE AND OBJECTIVES: The cervical spine is a high-risk area for percutaneous biopsy compared to the thoracic and lumbar regions. Biopsy of the cervical spine is less commonly undertaken, and previously published series on diagnostic yield and safety of cervical spine biopsy have been limited to 12 patients or less. The purpose of our study is to further define the diagnostic yield of computed tomography (CT)-guided biopsy for bony lesions identified in the cervical spine, by combining data from two large tertiary care referral centers...
August 20, 2016: Academic Radiology
Csaba Csutak, Claudia Ordeanu, Viorica Magdalena Nagy, Diana Cristina Pop, Sorana Daniela Bolboaca, Radu Badea, Liliana Chiorean, Sorin Marian Dudea
BACKGROUND AND AIM: Cervical cancer has high incidence and mortality in developing countries. It is the only gynecological malignancy that is clinically staged. Staging at the time of diagnosis is crucial for treatment planning. After radiation therapy, clinical examination is limited because of radiation changes. An imaging method relatively unaffected by radiation changes would be useful for the assessment of therapy results and for management. We sought to demonstrate the value of magnetic resonance imaging (MRI) in the pre- and post-treatment assessment of cervical cancer...
2016: Clujul Medical (1957)
David Ezra, Youssef Masharawi, Khalil Salame, Viviane Slon, Deborah Alperovitch-Najenson, Israel Hershkovitz
BACKGROUND CONTEXT: This cross-sectional study was conducted on the skeletal remains of individuals of known sex, age, and ethnic origin. The vertebral bodies of levels C3-C7 were measured and analyzed. Whereas many studies were performed on the size and shape of the vertebral bodies in the thoracic and lumbar spines, few have focused on the cervical vertebral bodies. Thus, there is insufficient data in the literature on the anatomy of the cervical spine, especially based on large study populations...
August 17, 2016: Spine Journal: Official Journal of the North American Spine Society
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