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Cervical insufficiency

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https://www.readbyqxmd.com/read/28804498/feasibility-of-cervical-epidural-anesthesia-for-breast-cancer-surgery
#1
Manuel Wenk, Christina Massoth, Daniel M Pöpping, Michael Möllmann
BACKGROUND: Effects of perioperative cervical level neuraxial blocks on the dissemination of cancer metastases have become a matter of substantial interest. However, experience with these catheters has been limited and data on feasibility and efficacy is sparse. METHODS: Data from 39 patients scheduled to undergo breast cancer surgery while awake with a cervical epidural alone was retrospectively analyzed. RESULTS: In 26 patients (66,7%, 95% CI 51,7-81,7) the cervical epidural catheter was sufficient for surgery...
2017: Anesthesiology Research and Practice
https://www.readbyqxmd.com/read/28799855/surgical-management-of-cervical-spine-deformity-in-chondrodysplasia-punctata
#2
Nobuhito Morota, Satoshi Ihara, Hideki Ogiwara, Goichiro Tamura
OBJECTIVE Chondrodysplasia punctata (CDP), a rare skeletal dysplasia, can lead to cervical spine instability and deformity. However, an optimal neurosurgical intervention has yet to be established. Thus, a retrospective study was conducted to assess the efficacy of various surgical interventions for children with CDP. METHODS The authors retrospectively reviewed 9 cases of CDP in which cervical decompression with or without posterior fusion was performed between April 2007 and May 2016. Patient demographics, preoperative clinical conditions, radiographic findings, surgical procedures, and the postoperative course were analyzed in detail...
August 11, 2017: Journal of Neurosurgery. Pediatrics
https://www.readbyqxmd.com/read/28781915/cervical-artificial-disc-extrusion-after-a-paragliding-accident
#3
Tianyi Niu, Haydn Hoffman, Daniel C Lu
BACKGROUND: Cervical total disc replacement (TDR) is an established alternative to anterior cervical discectomy and fusion (ACDF) with excellent long-term outcomes and low failure rates. Cases of implant failure and migration are scarce and primarily limited to several years postoperatively. The authors report a case of anterior extrusion of a C4-C5 ProDisc-C (DePuy Synthes, West Chester, PA, USA) cervical artificial disc (CAD) 14 months after placement due to minor trauma. CASE DESCRIPTION: A 33-year-old female who had undergone C4-C5 CAD implantation presented with neck pain and spasm after experiencing a paragliding accident...
2017: Surgical Neurology International
https://www.readbyqxmd.com/read/28780541/associations-between-highly-active-antiretroviral-therapy-and-the-presence-of-hpv-premalignant-and-malignant-cervical-lesions-in-sub-saharan-africa-a-systematic-review-current-evidence-and-directions-for-future-research
#4
Sonia Menon, Rodolfo Rossi, Natasha Zdraveska, Mbabazi Kariisa, Sushama D Acharya, Davy Vanden Broeck, Steven Callens
OBJECTIVES: In sub-Saharan Africa, substantial international funding along with evidence-based clinical practice have resulted in an unparalleled scale-up of access to antiretroviral treatment at a higher CD4 count. The role and timing of highly active antiretroviral therapy (HAART) in mediating cervical disease remains unclear. The aim of this article is to systematically review all evidence pertaining to Africa and identify research gaps regarding the epidemiological association between HAART use and the presence of premalignant/malignant cervical lesions...
August 4, 2017: BMJ Open
https://www.readbyqxmd.com/read/28778109/reference-ranges-for-ultrasonographic-measurements-of-the-uterine-cervix-in-low-risk-pregnant-women
#5
Kleber Cursino Andrade, Thaísa Guedes Bortoletto, Cristiane Martins Almeida, Renan Antonio Daniel, Heloísa Avo, Rodolfo Carvalho Pacagnella, José Guilherme Cecatti
Objective To define transvaginal ultrasound reference ranges for uterine cervix measurements according to gestational age (GA) in low-risk pregnancies. Methods Cohort of low-risk pregnant women undergoing transvaginal ultrasound exams every 4 weeks, comprising measurements of the cervical length and volume, the transverse and anteroposterior diameters of the cervix, and distance from the entrance of the uterine artery into the cervix until the internal os. The inter- and intraobserver variabilities were assessed with the linear correlation coefficient and the Student t-test...
August 4, 2017: Revista Brasileira de Ginecologia e Obstetrícia
https://www.readbyqxmd.com/read/28761411/the-crossed-phrenic-phenomenon
#6
REVIEW
Michael George Zaki Ghali
The cervical spine is the most common site of traumatic vertebral column injuries. Respiratory insufficiency constitutes a significant proportion of the morbidity burden and is the most common cause of mortality in these patients. In seeking to enhance our capacity to treat specifically the respiratory dysfunction following spinal cord injury, investigators have studied the "crossed phrenic phenomenon", wherein contraction of a hemidiaphragm paralyzed by a complete hemisection of the ipsilateral cervical spinal cord above the phrenic nucleus can be induced by respiratory stressors and recovers spontaneously over time...
June 2017: Neural Regeneration Research
https://www.readbyqxmd.com/read/28753545/adjuvant-administration-of-17-%C3%AE-hydroxy-progesterone-caproate-in-women-with-three-or-more-second-trimester-pregnancy-losses-undergoing-cervical-cerclage-is-no-more-effective-than-cerclage-alone
#7
Fernand D Samson, Amanda L Merriman, Danielle L Tate, Katherine Apostolakis-Kyrus, Luis M Gomez
OBJECTIVE: To investigate the role of adjuvant 17-α-hydroxy-progesterone caproate (17OHP-C) in reducing the risk of preterm delivery <34 weeks and adverse perinatal outcomes in women with ≥3 second trimester pregnancy losses attributed to cervical insufficiency undergoing prophylactic cerclage. MATERIAL AND METHODS: Retrospective cohort study of women with prophylactic cerclage placed between 2006 and 2014 divided into a cohort of (i) those receiving adjuvant 17OHP-C (n=43), and (ii) controls with cerclage alone (n=59)...
July 28, 2017: Journal of Perinatal Medicine
https://www.readbyqxmd.com/read/28742428/neck-and-upper-limb-dysfunction-in-patients-following-neck-dissection-looking-beyond-the-shoulder
#8
Elise M Gane, Shaun P O'Leary, Anna L Hatton, Benedict J Panizza, Steven M McPhail
Objective To measure patient-perceived upper limb and neck function following neck dissection and to investigate potential associations between clinical factors, symptoms, and function. Study Design Cross-sectional. Setting Two tertiary hospitals in Brisbane, Australia. Subjects and Methods Inclusion criteria: patients treated with neck dissection (2009-2014). EXCLUSION CRITERIA: aged <18 years, accessory nerve or sternocleidomastoid sacrifice, previous neck dissection, preexisting shoulder/neck injury, and inability to provide informed consent (cognition, insufficient English)...
July 1, 2017: Otolaryngology—Head and Neck Surgery
https://www.readbyqxmd.com/read/28717342/prevalence-of-high-risk-genotypes-of-human-papillomavirus-women-diagnosed-with-premalignant-and-malignant-pap-smear-tests-in-southern-ecuador
#9
Paola Dalgo Aguilar, Cisne Loján González, Ana Córdova Rodríguez, Katherine Acurio Páez, Ana Paulina Arévalo, Jana Bobokova
Human papillomavirus (HPV) is the primary infectious agent for the development of cervical cancer, although the presence of the virus alone is insufficient for viral development and proliferation; this can be attributed to the increase in potential oncogenic risk, along with other risk factors. In the present investigation, the prevalence of high-risk HPV was determined from samples of premalignant or malignant cervical cytology in women from the southern region of Ecuador. The kit we used was able to detect genotypes 16, 18, 31, 33, 35, 39, 45, 51, 52, 56, 58, and 59...
2017: Infectious Diseases in Obstetrics and Gynecology
https://www.readbyqxmd.com/read/28700733/non-invasive-prediction-of-preterm-birth-in-women-with-cervical-insufficiency-or-an-asymptomatic-short-cervix-%C3%A2-25-mm-by-measurement-of-biomarkers-in-the-cervicovaginal-fluid
#10
Ha-Na Yoo, Kyo Hoon Park, Eun Young Jung, Yu Mi Kim, Song Yi Kook, Se Jeong Jeon
OBJECTIVE: To determine whether various proteins in the cervicovaginal fluid (CVF) known to be involved in immune regulation, alone or in combination with clinical risk factors, can predict spontaneous preterm delivery (SPTD) in women with cervical insufficiency or a short cervix (≤25 mm). METHODS: This retrospective cohort study included 62 asymptomatic women with cervical insufficiency (n = 27) or an asymptomatic short cervix (n = 35) at 18-27 weeks. CVF swab samples were taken for assays of vitamin D binding protein (VDBP), interleukin (IL)-8, matrix metalloproteinases (MMP)-9, tissue inhibitor of metalloproteinases (TIMP)-1, and Dickkopf-related protein 3 (DKK3) before cervical examination, and maternal blood was collected for the determination of the C-reactive protein (CRP) level...
2017: PloS One
https://www.readbyqxmd.com/read/28700452/the-surgical-treatment-of-cervical-radiculopathy-meta-analysis-of-randomized-controlled-trials
#11
Gabriel Gutman, Derek H Rosenzweig, Jeff D Golan
STUDY DESIGN: Meta-analysis of published randomized controlled trials (RCTs). OBJECTIVE: To determine whether anterior cervical discectomy and fusion (ACDF), cervical disc replacement (CDR) or minimally invasive posterior cervical foraminotomy (MI-PCF) provides the best outcomes for patients with symptomatic single-level, single-side, cervical radiculopathy. SUMMARY OF BACKGROUND DATA: The surgical treatment of cervical radiculopathy is still controversial...
July 11, 2017: Spine
https://www.readbyqxmd.com/read/28679349/relationships-between-thermal-dose-parameters-and-the-efficacy-of-definitive-chemoradiotherapy-plus-regional-hyperthermia-in-the-treatment-of-locally-advanced-cervical-cancer-data-from-a-multicenter-randomized-clinical-trial
#12
Takayuki Ohguri, Yoko Harima, Hajime Imada, Hideyuki Sakurai, Tatsuya Ohno, Yoshiyuki Hiraki, Koh Tuji, Masahiro Tanaka, Hiromi Terashima
PURPOSE: To evaluate the contribution of the thermal dose parameters during regional hyperthermia (HT) treatment to the clinical outcomes in patients with cervical carcinoma (CC) who received chemoradiotherapy (CRT) plus HT. MATERIALS AND METHODS: Data from a multicenter randomized clinical trial of concurrent CRT+HT vs. CRT alone were used to evaluate the efficacy and safety of this combination therapy in the CC patients. The intrarectal temperatures of patients undergoing HT were recorded...
July 5, 2017: International Journal of Hyperthermia
https://www.readbyqxmd.com/read/28673792/cervical-cerclage-placement-decreases-local-levels-of-proinflammatory-cytokines-in-patients-with-cervical-insufficiency
#13
Stephany P Monsanto, Silvia Daher, Erika Ono, Karen Priscilla Tezotto Pendeloski, Évelyn Trainá, Rosiane Mattar, Chandrakant Tayade
BACKGROUND: Cervical insufficiency is characterized by premature, progressive dilation and shortening of the cervix during pregnancy. If left unattended, this can lead to the prolapse and rupture of the amniotic membrane, which usually results in midtrimester pregnancy loss or preterm birth. Previous studies have shown that proinflammatory cytokines such as interleukin-1β, interleukin-6, interleukin-8, and tumor necrosis factor alpha are up-regulated in normal parturition but are also associated with preterm birth...
June 30, 2017: American Journal of Obstetrics and Gynecology
https://www.readbyqxmd.com/read/28653217/health-related-quality-of-life-as-measured-by-the-eq-5d-in-the-prevention-screening-and-management-of-cervical-disease-a-systematic-review
#14
A Ó Céilleachair, J F O'Mahony, M O'Connor, J O'Leary, C Normand, C Martin, L Sharp
PURPOSE: Cost-effectiveness analyses (CEAs) of screening can be highly sensitive to the health-related quality of life (HRQoL) effects of screen tests and subsequent treatment. Accordingly, accurate assessment of HRQoL is essential. We reviewed the literature regarding HRQoL in cervical prevention and management in order to appraise the current evidence regarding this important input to CEA. METHODS: We searched the MEDLINE, Scopus and EconLit databases for studies that estimated HRQoL in cervical cancer prevention and management published January 1995-December 2015...
June 26, 2017: Quality of Life Research
https://www.readbyqxmd.com/read/28650133/imaging-in-primary-hyperparathyroidism-focus-on-the-evidence-based-diagnostic-performance-of-different-methods
#15
Giorgio Treglia, Pierpaolo Trimboli, Martin Huellner, Luca Giovanella
BACKGROUND: Primary hyperparathyroidism (PHPT) is a common endocrine disorder usually due to hyperfunctioning parathyroid glands (HP). Surgical removal of HP is the main treatment in PHPT, particularly in symptomatic patients. The correct detection and localization of HP is challenging and crucial as it may guide surgical treatment in patients with PHPT. To date, different imaging methods have been used to detect and localize HP in patients with PHPT including radiology, nuclear medicine and hybrid techniques...
June 23, 2017: Minerva Endocrinologica
https://www.readbyqxmd.com/read/28639273/a-single-center-retrospective-study-of-pregnancy-outcomes-after-emergency-cerclage-for-cervical-insufficiency
#16
Sheng Wang, Ling Feng
OBJECTIVE: To compare maternal and perinatal outcomes after emergency cerclage with those after elective cerclage. METHODS: In a retrospective review, data were assessed from women with a viable singleton pregnancy who underwent elective or emergency cerclage for cervical insufficiency at the Tongji Hospital, Wuhan, China, between January 2010 and July 2015. Subgroup analyses based on cervical length (CL; ≤15, 15-25, and 25-30 mm) were also conducted among women undergoing emergency cerclage...
June 22, 2017: International Journal of Gynaecology and Obstetrics
https://www.readbyqxmd.com/read/28626412/congenital-bilateral-c2-transverse-foramina-stenosis-causing-adult-onset-vertebrobasilar-insufficiency-and-posterior-circulation-stroke
#17
Ajeet Gordhan, Catherine Lockhart
Vertebrobasilar insufficiency leading to posterior circulation infarcts caused by congenital hypoplasia of the bilateral transverse foramina at the C2 level, affecting the caliber and flow of the bilateral distal cervical vertebral arteries in an adult, has not been previously reported. A 41-year-old male presented with episodic dizziness for a period of 1 year prior to consultation. Computed tomography angiography of the head and neck demonstrated congenital hypoplasia of the bilateral C2 transverse foramina, with absence of the vertebral arteries in each of the foramina and collateral reconstitution of diminutive intracranial vertebral artery segments...
May 2017: Case Reports in Neurology
https://www.readbyqxmd.com/read/28608497/the-effect-of-hpv-infection-on-ivf-outcomes-a-systematic-review-and-meta-analysis
#18
REVIEW
Charalampos Siristatidis, Dennis Vaidakis, Eleni Sertedaki, Wellington Martins
OBJECTIVES: Tο identify, appraise and summarize the available data, concerning the impact of HPV infection on the reproductive outcomes following in vitro fertilization (IVF). METHODS: We searched for studies on PubMed, Embase, Scopus, Lilacs and the Cochrane Central Register of Controlled Trials from inception to Mar-2017. Any type of HPV infection in the woman assessed through PCR, subfertility factors and IVF indications and protocols were considered. Our primary outcomes were live birth/ongoing pregnancy and miscarriage, while secondary included clinical and laboratory parameters...
June 13, 2017: Ultrasound in Obstetrics & Gynecology
https://www.readbyqxmd.com/read/28604460/intention-to-treat-analysis-of-radical-trachelectomy-for-early-stage-cervical-cancer-with-special-reference-to-oncologic-failures-single-institutional-experience-in-hungary
#19
Robert Póka, Szabolcs Molnár, Péter Daragó, János Lukács, Rudolf Lampé, Zoárd Krasznai, Zoltán Hernádi
OBJECTIVE: The aim of our study was to evaluate clinical and pathological data in order to draw eligibility criteria for oncologically sufficient radical trachelectomy (RT) in early-stage cervical cancer. Reviewing all cases of attempted RT performed at our unit, we focused attention on prognostic indicators of the need for additional oncologic treatment following RT. The analysis was extended by extensive literature review to include previously published cases of oncologic failures. METHODS: The authors retrospectively analyzed data of patients who underwent RT at the Department of Obstetrics and Gynecology, University of Debrecen...
June 10, 2017: International Journal of Gynecological Cancer
https://www.readbyqxmd.com/read/28601994/radiologic-features-of-dropped-head-syndrome-in-the-overall-sagittal-alignment-of-the-spine
#20
Kazuki Hashimoto, Hiroshi Miyamoto, Terumasa Ikeda, Masao Akagi
PURPOSE: Dropped head syndrome (DHS) is a rare clinical entity which is defined as a chin-on-chest deformity in the standing or sitting position, resulting from sagittal imbalance of the cervical region. The purpose of the present study was to clarify the radiologic features of DHS in the overall sagittal alignment of the spine. We also investigated the changes in sagittal alignment after correction surgery for DHS. METHODS: Twenty DHS patients [1 male and 19 female, with an average age of 78...
June 10, 2017: European Spine Journal
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