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Cervical insufficiency

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https://www.readbyqxmd.com/read/28653217/health-related-quality-of-life-as-measured-by-the-eq-5d-in-the-prevention-screening-and-management-of-cervical-disease-a-systematic-review
#1
A Ó Céilleachair, J F O'Mahony, M O'Connor, J O'Leary, C Normand, C Martin, L Sharp
PURPOSE: Cost-effectiveness analyses (CEAs) of screening can be highly sensitive to the health-related quality of life (HRQoL) effects of screen tests and subsequent treatment. Accordingly, accurate assessment of HRQoL is essential. We reviewed the literature regarding HRQoL in cervical prevention and management in order to appraise the current evidence regarding this important input to CEA. METHODS: We searched the MEDLINE, Scopus and EconLit databases for studies that estimated HRQoL in cervical cancer prevention and management published January 1995-December 2015...
June 26, 2017: Quality of Life Research
https://www.readbyqxmd.com/read/28650133/imaging-in-primary-hyperparathyroidism-focus-on-the-evidence-based-diagnostic-performance-of-different-methods
#2
Giorgio Treglia, Pierpaolo Trimboli, Martin Huellner, Luca Giovanella
BACKGROUND: Primary hyperparathyroidism (PHPT) is a common endocrine disorder usually due to hyperfunctioning parathyroid glands (HP). Surgical removal of HP is the main treatment in PHPT, particularly in symptomatic patients. The correct detection and localization of HP is challenging and crucial as it may guide surgical treatment in patients with PHPT. To date, different imaging methods have been used to detect and localize HP in patients with PHPT including radiology, nuclear medicine and hybrid techniques...
June 23, 2017: Minerva Endocrinologica
https://www.readbyqxmd.com/read/28639273/a-single-center-retrospective-study-of-pregnancy-outcomes-after-emergency-cerclage-for-cervical-insufficiency
#3
Sheng Wang, Ling Feng
OBJECTIVE: To compare maternal and perinatal outcomes after emergency cerclage with those after elective cerclage. METHODS: In a retrospective review, data were assessed from women with a viable singleton pregnancy who underwent elective or emergency cerclage for cervical insufficiency at the Tongji Hospital, Wuhan, China, between January 2010 and July 2015. Subgroup analyses based on cervical length (CL; ≤15, 15-25, and 25-30 mm) were also conducted among women undergoing emergency cerclage...
June 22, 2017: International Journal of Gynaecology and Obstetrics
https://www.readbyqxmd.com/read/28626412/congenital-bilateral-c2-transverse-foramina-stenosis-causing-adult-onset-vertebrobasilar-insufficiency-and-posterior-circulation-stroke
#4
Ajeet Gordhan, Catherine Lockhart
Vertebrobasilar insufficiency leading to posterior circulation infarcts caused by congenital hypoplasia of the bilateral transverse foramina at the C2 level, affecting the caliber and flow of the bilateral distal cervical vertebral arteries in an adult, has not been previously reported. A 41-year-old male presented with episodic dizziness for a period of 1 year prior to consultation. Computed tomography angiography of the head and neck demonstrated congenital hypoplasia of the bilateral C2 transverse foramina, with absence of the vertebral arteries in each of the foramina and collateral reconstitution of diminutive intracranial vertebral artery segments...
May 2017: Case Reports in Neurology
https://www.readbyqxmd.com/read/28608497/the-effect-of-hpv-infection-on-ivf-outcomes-a-systematic-review-and-meta-analysis
#5
REVIEW
Charalampos Siristatidis, Dennis Vaidakis, Eleni Sertedaki, Wellington Martins
OBJECTIVES: Tο identify, appraise and summarize the available data, concerning the impact of HPV infection on the reproductive outcomes following in vitro fertilization (IVF). METHODS: We searched for studies on PubMed, Embase, Scopus, Lilacs and the Cochrane Central Register of Controlled Trials from inception to Mar-2017. Any type of HPV infection in the woman assessed through PCR, subfertility factors and IVF indications and protocols were considered. Our primary outcomes were live birth/ongoing pregnancy and miscarriage, while secondary included clinical and laboratory parameters...
June 13, 2017: Ultrasound in Obstetrics & Gynecology
https://www.readbyqxmd.com/read/28604460/intention-to-treat-analysis-of-radical-trachelectomy-for-early-stage-cervical-cancer-with-special-reference-to-oncologic-failures-single-institutional-experience-in-hungary
#6
Robert Póka, Szabolcs Molnár, Péter Daragó, János Lukács, Rudolf Lampé, Zoárd Krasznai, Zoltán Hernádi
OBJECTIVE: The aim of our study was to evaluate clinical and pathological data in order to draw eligibility criteria for oncologically sufficient radical trachelectomy (RT) in early-stage cervical cancer. Reviewing all cases of attempted RT performed at our unit, we focused attention on prognostic indicators of the need for additional oncologic treatment following RT. The analysis was extended by extensive literature review to include previously published cases of oncologic failures. METHODS: The authors retrospectively analyzed data of patients who underwent RT at the Department of Obstetrics and Gynecology, University of Debrecen...
June 10, 2017: International Journal of Gynecological Cancer
https://www.readbyqxmd.com/read/28601994/radiologic-features-of-dropped-head-syndrome-in-the-overall-sagittal-alignment-of-the-spine
#7
Kazuki Hashimoto, Hiroshi Miyamoto, Terumasa Ikeda, Masao Akagi
PURPOSE: Dropped head syndrome (DHS) is a rare clinical entity which is defined as a chin-on-chest deformity in the standing or sitting position, resulting from sagittal imbalance of the cervical region. The purpose of the present study was to clarify the radiologic features of DHS in the overall sagittal alignment of the spine. We also investigated the changes in sagittal alignment after correction surgery for DHS. METHODS: Twenty DHS patients [1 male and 19 female, with an average age of 78...
June 10, 2017: European Spine Journal
https://www.readbyqxmd.com/read/28594754/false-labor-at-term-in-singleton-pregnancies-discharge-after-a-standardized-assessment-and-perinatal-outcomes
#8
David B Nelson, Donald D McIntire, Kenneth J Leveno
OBJECTIVE: To evaluate perinatal outcomes in women sent home with a diagnosis of false labor at term and assess the time interval to return for delivery. METHODS: This was a prospective observational cohort study of women at 37 0/7 to 41 6/7 weeks of gestation without pre-existing medical complications who presented to our hospital-based triage unit with symptoms of labor and underwent a standardized evaluation. Women diagnosed as having false labor with a live singleton fetus in cephalic presentation without a prior cesarean delivery and sent home were compared with a group of similar women diagnosed to be in spontaneous labor...
June 6, 2017: Obstetrics and Gynecology
https://www.readbyqxmd.com/read/28593385/tailor-made-management-of-thoracic-scoliosis-with-cervical-hyperextension-in-muscular-dystrophy
#9
A Angelliaume, L Harper, A Lalioui, A Delgove, Y Lefèvre
PURPOSE: We report the case of a 13-year-old boy managed for fixed cervical hyperextension due to congenital muscular dystrophy with partial merosin deficiency. He presented a right decompensated thoracic scoliosis (T6-L1 Cobb angle 72°) associated with cervical and lumbar lordosis. The spinal extension was accompanied by major flexion of the hip resulting in the trunk being bent forward. This posture caused daily severe back pain responsible for significant loss of quality of life. This led to the decision to perform surgery...
June 7, 2017: European Spine Journal
https://www.readbyqxmd.com/read/28592693/non-genomic-actions-of-17-%C3%AE-estradiol-restore-respiratory-neuroplasticity-in-young-ovariectomized-female-rats
#10
Brendan J Dougherty, Elizabeth S Kopp, Jyoti J Watters
Gonadal steroids modulate CNS plasticity, including phrenic long-term facilitation (pLTF), a form of spinal respiratory neuroplasticity resulting in increased phrenic nerve motor output following exposure to acute intermittent hypoxia (aIH; three 5 min episodes, 10.5% O2). Despite the importance of respiratory system neuroplasticity, and its dependence on estrogen in males, little is known about pLTF expression or mechanisms of estrogen signaling in females. Here, we tested the hypotheses that: 1) pLTF expression in young, gonadally intact female rats would be expressed during estrous cycle stages in which 17β-estradiol (E2) is naturally high (e...
June 7, 2017: Journal of Neuroscience: the Official Journal of the Society for Neuroscience
https://www.readbyqxmd.com/read/28583457/vertebrobasilar-insufficiency-due-to-distal-posterior-inferior-cerebellar-artery-compression-in-chiari-1-5
#11
M Burhan Janjua, Iryna Ivasyk, Jeffrey P Greenfield
Chiari malformation is characterized by radiographic evidence of herniation of cerebellar tonsils below the foramen magnum, and symptoms complex of headaches, breathing, swallowing or sleep difficulties, ataxia, restless, motor and/or sensory deficits. We report a case of a 34-year old female whose imaging indicated a Chiari 1.5 with brainstem (caudal medulla) herniation, and an expansive cervical syrinx. Her symptom complex showed signs both of cervical syringomyelia, as well as ones localizable to the medulla...
June 2, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28575244/venous-superdrained-gastric-tube-pull-up-procedure-for-hypopharyngeal-and-cervical-esophageal-reconstruction-reduces-postoperative-anastomotic-leakage-and-stricture
#12
M Fujioka, K Hayashida, K Fukui, S Ishiyama, H Saijo, K Taniguchi
Gastric pull-up is a common procedure to reconstruct the continuity of the upper digestive tract after esophageal resection. However, this technique sometimes causes postoperative anastomotic leakage or stricture, resulting from insufficient blood flow at the distal end. To overcome this problem, additional microvascular venous anastomoses were performed. The purpose of this study was to compare the outcomes of post-surgical anastomotic leakage and stricture in patients with and without additional microvascular venous superdrainage after cervical esophageal and hypopharyngeal resection and gastric tube reconstruction...
August 1, 2017: Diseases of the Esophagus: Official Journal of the International Society for Diseases of the Esophagus
https://www.readbyqxmd.com/read/28574931/neoadjuvant-weekly-paclitaxel-carboplatin-is-effective-in-stage-i-ii-cervical-cancer
#13
Rawand Salihi, Karin Leunen, Philippe Moerman, Frédéric Amant, Patrick Neven, Ignace Vergote
OBJECTIVE: Neoadjuvant chemotherapy (NACT) followed by surgery in cervical cancer is widely studied with paclitaxel-ifosfamide-cisplatinum 3 weekly (TIP). Although the response rates with TIP are high, the toxicity is substantial. Therefore, this study evaluates dose-dense paclitaxel-carboplatin (TC) as an alternative. METHODS: In this prospective phase 2 study trial, we included 36 patients with International Federation of Gynecology and Obstetrics (FIGO) stage IB1 to IIB cervical cancer, who received 9 weeks' NACT dose-dense TC (median weekly dose paclitaxel 60 mg/m, carboplatinum area under the curve 2...
June 1, 2017: International Journal of Gynecological Cancer
https://www.readbyqxmd.com/read/28550670/-analysis-of-the-risk-factors-for-postoperative-cervical-anastomotic-leakage-after-mckeown-s-esophagectomy
#14
G F Zhao, K P Zhang, S G Gao, J W Mu, Y S Mao, D L Wang, Y S Gao, F Lyu, L Zhao, Q Xue
Objective: To analyze risk factors of anastomotic leakage after McKeown'sesophagectomy. Methods: The clinical data of 635 esophageal cancer patients, who underwent McKeown's esophagectomy at Cancer Hospital of Chinese Academy of Medical Sciences from January 2012 to December 2015, were retrospectively analyzed. The risk factors of cervical anastomotic leakage were identified through analysis of medical history, surgical procedure, tumor characteristics and vascular calcification. Results: Among all the 635 patients, anastomotic leakage occurred in 111 (17...
April 23, 2017: Zhonghua Zhong Liu za Zhi [Chinese Journal of Oncology]
https://www.readbyqxmd.com/read/28550430/robotic-transabdominal-cerclage-a-case-series-illustrating-costs
#15
Rebecca Lee, David Biats, Melissa Mancuso
The incidence of cervical insufficiency is 0.1-1% of all pregnancies and 8% of second trimester losses. After failed vaginal cerclages or in patients with amputated or congenitally abnormal cervices, transabdominal cerclages may be performed. Recent advances allow for use of the da Vinci robot to perform transabdominal cerclages. This case series presents three cases of robotically placed cerclages, performed prior to pregnancy. All patients had experienced prior second trimester losses. Two of the three had previously failed vaginal cerclage placement...
May 26, 2017: Journal of Robotic Surgery
https://www.readbyqxmd.com/read/28546709/salvage-surgery-for-cervical-cancer-recurrences
#16
P Rema, Arun Peter Mathew, S Suchetha, Iqbal Ahmed
Cervical cancer usually presents in advanced stages and is treated with chemoradiation. About 15-20 % patients present with local recurrence after chemoradiation. Radical surgical resection is the only treatment modality offering long term survival benefit in recurrent cervical cancer. The most common surgical option for these patients is pelvic exenteration. Radical hysterectomy may be done for patients with a small centrally located recurrence in the cervix with no infiltration of adjacent structures. The aim of this study was to evaluate the morbidity and survival outcome following radical hysterectomy and pelvic exenteration for recurrent cancer cervix...
June 2017: Indian Journal of Surgical Oncology
https://www.readbyqxmd.com/read/28541855/rate-and-reasons-for-repeat-ct-scanning-in-transferred-trauma-patients
#17
James F Holmes, Blake G Siglock, Michael T Corwin, Michael A Johnson, Edgardo S Salcedo, Gabriel S Espinoza, Ramit Lamba
To describe the reasons and additional radiation for CT scans repeated after transfer to a trauma center. Retrospective study of patients transferred to a trauma center. Patients had repeat CT if a CT of the same region was repeated at the trauma center's emergency department. Indications for repeat CT scanning were abstracted. Radiation dosage was calculated in millisieverts. A total of 370 had CT scans and were transferred. Mean age was 39.1 ± 28.0 years. Seventy-four [20.0%, 95% confidence interval (CI) 16...
May 1, 2017: American Surgeon
https://www.readbyqxmd.com/read/28530494/review-anal-intraepithelial-neoplasia-in-hiv-infected-men-who-have-sex-with-men-is-screening-and-treatment-justified
#18
Peter Wasserman, David S Rubin, Glenn Turett
Anal squamous cell carcinoma (SCC) is the fourth most prevalent cancer in human immunodeficiency virus (HIV)-infected men who have sex with men (MSM). Human papillomavirus (HPV) has been detected in over 90% of anal carcinoma biopsy specimens from MSM, and is considered a necessary, but alone, insufficient factor for carcinogenesis. Anal intraepithelial neoplasia (AIN) may be precursive for SCC, and screening cytology with referral of persons with abnormality for high-resolution anoscopy-guided biopsy, and AIN treatment, has been recommended for prevention...
June 2017: AIDS Patient Care and STDs
https://www.readbyqxmd.com/read/28526877/magnetospinography-visualizes-electrophysiological-activity-in-the-cervical-spinal-cord
#19
Satoshi Sumiya, Shigenori Kawabata, Yuko Hoshino, Yoshiaki Adachi, Kensuke Sekihara, Shoji Tomizawa, Masaki Tomori, Senichi Ishii, Kyohei Sakaki, Dai Ukegawa, Shuta Ushio, Taishi Watanabe, Atsushi Okawa
Diagnosis of nervous system disease is greatly aided by functional assessments and imaging techniques that localize neural activity abnormalities. Electrophysiological methods are helpful but often insufficient to locate neural lesions precisely. One proposed noninvasive alternative is magnetoneurography (MNG); we have developed MNG of the spinal cord (magnetospinography, MSG). Using a 120-channel superconducting quantum interference device biomagnetometer system in a magnetically shielded room, cervical spinal cord evoked magnetic fields (SCEFs) were recorded after stimulation of the lower thoracic cord in healthy subjects and a patient with cervical spondylotic myelopathy and after median nerve stimulation in healthy subjects...
May 19, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28524247/comparison-of-adjuvant-therapy-for-node-positive-clinical-stage-ib-iib-cervical-cancer-systemic-chemotherapy-versus-pelvic-irradiation
#20
Koji Matsuo, Muneaki Shimada, Yoichi Aoki, Masaru Sakamoto, Nobuhiro Takeshima, Hisaya Fujiwara, Takashi Matsumoto, Mikio Mikami, Toru Sugiyama
This was a nation-wide retrospective study in Japan examining women who underwent radical hysterectomy for clinical stage IB-IIB cervical cancer with pelvic and/or para-aortic lymph node metastasis between 2004 and 2008. Time to recurrence or death and patterns of disease recurrence were compared based upon the adjuvant treatment pattern: whole pelvic radiotherapy alone (n=253), concurrent chemo-radiotherapy (CCRT, n=502), and chemotherapy alone (n=319). Women who received chemotherapy alone had similar recurrence (5-year rates, 36...
May 19, 2017: International Journal of Cancer. Journal International du Cancer
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