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https://www.readbyqxmd.com/read/29148828/increased-cellular-aging-by-3-years-of-age-in-latino-preschool-children-who-consume-more-sugar-sweetened-beverages-a-pilot-study
#1
Janet M Wojcicki, Rosalinda Medrano, Jue Lin, Elissa Epel
BACKGROUND: Previous studies in adults and older children find that sugar-sweetened beverage (SSB) consumption increases risk for obesity and cellular aging, as measured by leukocyte telomere length (LTL). METHODS: In a previously described, San Francisco-based Latino birth cohort, where telomere length was measured at birth, we evaluate the relationship between beverage consumption (including SSB and 100% fruit juice), obesity, and LTL at 2-3 years old, as well as change in LTL from birth...
November 17, 2017: Childhood Obesity
https://www.readbyqxmd.com/read/29146122/health-and-wellbeing-of-indigenous-adolescents-in-australia-a-systematic-synthesis-of-population-data
#2
Peter S Azzopardi, Susan M Sawyer, John B Carlin, Louisa Degenhardt, Ngiare Brown, Alex D Brown, George C Patton
BACKGROUND: Indigenous populations have high rates of disease and premature mortality. Most Indigenous communities are young, and adolescence (age 10-24 years) provides great opportunities for population health gain. However, the absence of a comprehensive account of Indigenous adolescents' health has been a barrier to effective policy. We aimed to report a national health profile for Indigenous adolescents in Australia. METHODS: We undertook a systematic synthesis of population data to report the health and wellbeing of Indigenous adolescents in Australia...
November 10, 2017: Lancet
https://www.readbyqxmd.com/read/29146007/-psoriatic-arthritis-in-france-from-infants-to-the-elderly-findings-from-two-cross-sectional-multicenter-studies
#3
A Galezowski, F Maccari, S Hadj-Rabia, M-L Sigal, A Phan, M Lahfa, A-C Bursztejn, H Barthélémy, F Boralévi, Z Reguiai, C Chiavérini, E Estève, E Bourrat, M Ruer-Mulard, A Beauchet, E Mahé
BACKGROUND: Psoriatic arthritis affects 20-30% of patients with psoriasis. Few epidemiological data are available in France about its prevalence and its association with skin lesions and comorbidities. OBJECTIVES: To assess the epidemiological aspects and the risk factors for psoriatic arthritis in children and adults in France. METHODS: Two cross-sectional studies were conducted in France in children (χ-Psocar, 23 pediatric dermatology centers belonging to the SFDP, 1 year) and adults (Resopsocar, 29 dermatology centers belonging to GEM RESOPSO, 4 months) to study the link between psoriasis and cardiovascular and metabolic comorbidities...
November 13, 2017: Annales de Dermatologie et de Vénéréologie
https://www.readbyqxmd.com/read/29138878/higher-cost-of-hospitalizations-for-non-cardiac-diagnoses-in-adults-with-congenital-heart-disease
#4
Michael D Seckeler, Ian D Thomas, Jennifer Andrews, Omar Meziab, Tabitha Moe, Elissa Heller, Scott E Klewer
Adults with congenital heart disease (CHD) are a rapidly increasing population and their impact on healthcare resources is not fully understood. The purpose of this study was to describe the costs of hospitalizations for non-cardiac disease for adults with CHD. We conducted a retrospective review of hospital discharge data from the University HealthSystem Consortium Clinical Data Base/Resource Manager from January 2011 through December 2013. Patients were ≥ 18 years old at admission with any ICD-9 code for moderate or high severity CHD; cardiac surgical admissions were excluded...
November 15, 2017: Pediatric Cardiology
https://www.readbyqxmd.com/read/29138256/low-neonatal-plasma-n-6-n-3-pufa-ratios-regulate-offspring-adipogenic-potential-and-condition-adult-obesity-resistance
#5
Michael C Rudolph, Matthew R Jackman, David M Presby, Julie A Houck, Patricia G Webb, Ginger C Johnson, Taylor K Soderborg, Becky A de la Houssaye, Ivana V Yang, Jacob E Friedman, Paul S MacLean
Adipose tissue expansion (ATE) progresses rapidly during postnatal life, influenced by both prenatal maternal factors and postnatal developmental cues. The ratio of n-6 relative to n-3 polyunsaturated fatty acids (PUFA) is thought to regulate perinatal adipogenesis, but the cellular mechanisms and long-term effects are not well understood. We lowered the fetal and postnatal n-6/n-3 PUFA ratio exposure in wildtype offspring, under standard maternal dietary fat amounts, to test effects of low n-6/n-3 ratios on offspring adipogenesis and adipogenic potential...
November 14, 2017: Diabetes
https://www.readbyqxmd.com/read/29136748/-follow-up-study-of-body-mass-index-and-risk-of-cognitive-impairment-among-elderly-adults-aged-%C3%A2-65-years-old-from-longevity-areas-of-china
#6
J Zhang, Y B Lyu, Z X Yin, J S Luo, W H Shi, X M Shi
Objective: To discuss the relationship between body mass index (BMI) and cognitive impairment among elderly adults aged ≥65 years old from longevity areas of China. Methods: A total of 2 439 elderly adults from 8 longevity areas were included in our baseline survey by answering questionnaire and taking body measurements and blood biochemical examinations in 2012. In the follow-up study in 2014, we studied the cognitive impairment status among the 1 135 elderly adults aging ≥65 years old. Multivariate logistic regression model was used to analyze the relationship between BMI and cognitive impairment risk...
November 6, 2017: Zhonghua Yu Fang Yi Xue za Zhi [Chinese Journal of Preventive Medicine]
https://www.readbyqxmd.com/read/29132553/dysregulation-of-glucose-metabolism-since-young-adulthood-increases-the-risk-of-cardiovascular-diseases-in-patients-with-bipolar-disorder
#7
Pao-Huan Chen, Yen-Kuang Lin, Chi-Kang Chang, Shuo-Ju Chiang, Shang-Ying Tsai
Aging patients with bipolar disorder (BD) are at a high risk of cardiovascular diseases (CVDs). However, few studies have directly examined the association between metabolic risks and CVDs in patients with BD across the lifespan. Therefore, the aim of this study was to determine lifetime metabolic risk factors for CVDs in patients with BD. We recruited BD-I patients who were more than 50 years old and had had at least one psychiatric hospitalization. Patients who had a cardiologist-confirmed CVD diagnosis (ICD-9 code 401-414) were assigned to the case group...
December 2017: Kaohsiung Journal of Medical Sciences
https://www.readbyqxmd.com/read/29120831/epidemiology-of-areca-betel-nut-use-in-the-mariana-islands-findings-from-the-university-of-guam-university-of-hawai-i-cancer-center-partnership-program
#8
Yvette C Paulino, Eric L Hurwitz, Joanne C Ogo, Tristan C Paulino, Ashley B Yamanaka, Rachel Novotny, Lynne R Wilkens, Mary Jane Miller, Neal A Palafox
BACKGROUND: Areca (betel) nut is considered a Group 1 human carcinogen shown to be associated with other chronic diseases in addition to cancer. This paper describes the areca (betel) nut chewing trend in Guam, and health behaviors of chewers in Guam and Saipan. METHODS: The areca (betel) nut module in the Guam Behavioral Risk Factor Surveillance Survey was used to calculate the 5-year (2011-2015) chewing trend. To assess the association between areca (betel) nut chewing and health risks in the Mariana Islands, a cross-section of 300 chewers, ≥18years old, were recruited from households in Guam and Saipan...
October 2017: Cancer Epidemiology
https://www.readbyqxmd.com/read/29115080/prevalences-and-management-of-diabetes-and-pre-diabetes-among-korean-teenagers-and-young-adults-results-from-the-korea-national-health-and-nutrition-examination-survey-2005-2014
#9
Eun Hee Cho, Dayeon Shin, Keun Hyok Cho, Junguk Hur
The rapid increases in childhood obesity and physical inactivity are linked to the incidence of diabetes among young individuals. However, few studies have evaluated the prevalence of diabetes among this population. Therefore, we used Korea National Health and Nutrition Examination Survey (KNHANES) data to evaluate the prevalence and management of diabetes and pre-diabetes among young Koreans. We evaluated KNHANES data (2005-2014) from 10-29-year-old individuals. Individuals were considered eligible if they had completed the health examination and the health interview survey, and we excluded individuals with missing data regarding fasting glucose or glycated haemoglobin levels...
December 2017: Journal of Korean Medical Science
https://www.readbyqxmd.com/read/29108814/waist-to-height-ratio-and-sedentary-lifestyle-as-predictors-of-metabolic-syndrome-in-children-in-ecuador
#10
F Aguirre P, A Coca, M F Aguirre, G Celis
OBJECTIVE: To determine the predictors and prevalence of metabolic syndrome (MS) and the presence of vascular inflammation in apparently-normal children (10-15 years) of both sexes in Guayaquil, Ecuador. STUDY DESIGN AND METHODS: We included 395 apparently-healthy students from a middle-income school in a cross-sectional survey. Informed consent was obtained from students and parents. Anthropometric measurements including blood pressure (BP), body mass index (BMI) and waist-to-height ratio (WHtR), and blood tests were recorded...
November 3, 2017: Hipertensión y Riesgo Vascular
https://www.readbyqxmd.com/read/29107881/increased-estrogen-level-can-be-associated-with-depression-in-males
#11
Daniela Stanikova, Tobias Luck, Yoon Ju Bae, Joachim Thiery, Uta Ceglarek, Christoph Engel, Cornelia Enzenbach, Kerstin Wirkner, Juraj Stanik, Juergen Kratzsch, Steffi G Riedel-Heller
BACKGROUND: Several studies have shown a positive association between depression and obesity; however the underlying mechanisms are not fully understood. It is not known if this association is driven by altered sex hormone levels in men due to increased BMI. PATIENTS AND METHODS: Data were obtained from the LIFE-Adult-Study, a population-based cohort study. A total of 3925 men (2244<60years and 1681>60years) were included into analyses. Associations between BMI, sex hormones and depressive symptomatology according to CES-D score were evaluated...
November 2, 2017: Psychoneuroendocrinology
https://www.readbyqxmd.com/read/29099963/activity-of-the-hypothalamic-melanocortin-system-decreases-in-middle-aged-and-increases-in-old-rats
#12
Nóra Füredi, Alexandra Mikó, Balázs Gaszner, Diána Feller, Ildikó Rostás, Judit Tenk, Margit Solymár, Márta Balaskó, Erika Pétervári
Appearance of middle-aged obesity and aging anorexia both in humans and rodents suggests a role for regulatory alterations. Hypothalamic melanocortin agonist, alpha-melanocyte-stimulating hormone (alpha-MSH) produced in the arcuate nucleus (ARC) reduces body weight via inducing hypermetabolism and anorexia mainly through melanocortin 4 receptors (MC4R) in the paraventricular nucleus (PVN). Orexigenic ARC-derived agouti-related protein (AgRP) is an inverse agonist on MC4R in the PVN. Previously we demonstrated that characteristic age-related shifts in the catabolic effects of alpha-MSH may contribute both to middle-aged obesity and aging anorexia...
November 1, 2017: Journals of Gerontology. Series A, Biological Sciences and Medical Sciences
https://www.readbyqxmd.com/read/29090343/epidemiological-genetic-and-clinical-characterization-by-age-of-newly-diagnosed-acute-myeloid-leukemia-based-on-an-academic-population-based-registry-study-amlsg-bio
#13
Gabriele Nagel, D Weber, E Fromm, S Erhardt, M Lübbert, W Fiedler, T Kindler, J Krauter, P Brossart, A Kündgen, H R Salih, J Westermann, G Wulf, B Hertenstein, M Wattad, K Götze, D Kraemer, T Heinicke, M Girschikofsky, H G Derigs, H A Horst, C Rudolph, M Heuser, G Göhring, V Teleanu, L Bullinger, F Thol, V I Gaidzik, P Paschka, K Döhner, A Ganser, Hartmut Döhner, R F Schlenk
We describe genetic and clinical characteristics of acute myeloid leukemia (AML) patients according to age from an academic population-based registry. Adult patients with newly diagnosed AML at 63 centers in Germany and Austria were followed within the AMLSG BiO registry (NCT01252485). Between January 1, 2012, and December 31, 2014, data of 3525 patients with AML (45% women) were collected. The median age was 65 years (range 18-94). The comparison of age-specific AML incidence rates with epidemiological cancer registries revealed excellent coverage in patients < 70 years old and good coverage up to the age of 80...
October 31, 2017: Annals of Hematology
https://www.readbyqxmd.com/read/29090036/the-autoimmunity-s-footprint-in-pediatrics-type-1-diabetes-coeliac-disease-thyroiditis
#14
Anca Orzan, Carmen Novac, Mihaela Mihu, Constantin Ionescu Tirgoviste, Mihaela Balgradean
The present case report aims to describe and discuss the approach for the management of difficult endotracheal intubation in an adult with Down syndrome undergoing cataract surgery. A 26-year-old female with Down syndrome and a validated diagnosis of cataract requiring surgery was examined in order to assess the degree of difficulty of endotracheal intubation. Patients with Down syndrome have characteristic craniofacial abnormalities which require a thorough pre-operative assessment to anticipate and prepare for a difficult endotracheal intubation...
June 2017: Mædica
https://www.readbyqxmd.com/read/29090034/endotracheal-intubation-in-a-down-syndrome-adult-undergoing-cataract-surgery-a-multidisciplinary-approach
#15
George Gabriel Moldoveanu, Emilia Severin, Andreea Paun
The present case report aims to describe and discuss the approach for the management of difficult endotracheal intubation in an adult with Down syndrome undergoing cataract surgery. A 26-year-old female with Down syndrome and a validated diagnosis of cataract requiring surgery was examined in order to assess the degree of difficulty of endotracheal intubation. Patients with Down syndrome have characteristic craniofacial abnormalities which require a thorough pre-operative assessment to anticipate and prepare for a difficult endotracheal intubation...
June 2017: Mædica
https://www.readbyqxmd.com/read/29076960/effects-of-combined-strength-and-endurance-training-on-physical-performance-and-biomarkers-of-healthy-young-women
#16
Heikki KyrÖlÄinen, Anthony C Hackney, Riikka Salminen, Johanna Repola, Keijo HÄkkinen, Jari Haimi
Cardiovascular fitness has decreased and obesity has increased in youth-adults world-wide during the last ten years. Therefore, there is an urgent need to find out optimal exercise training programs for improving physical performance and health outcomes, especially, among sedentary women. Subjects were 25-30-year-old females with very low physical activity, and 65 % of them were overweight (BMI >25). They performed endurance and strength training three times a week for nine weeks. Independent strength training and instructed endurance training by indoor cycling were prescribed...
October 20, 2017: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/29064168/high-prevalence-of-hiv-and-non-communicable-disease-ncd-risk-factors-in-rural-kwazulu-natal-south-africa
#17
Alastair van Heerden, Ruanne V Barnabas, Shane A Norris, Lisa K Micklesfield, Heidi van Rooyen, Connie Celum
INTRODUCTION: South Africa faces epidemics of HIV and non-communicable diseases (NCDs). The aim of this study was to characterize the prevalence of non-communicable disease risk factors and depression, stratified by HIV status, in a community with a high burden of HIV. METHODS: We conducted a home-based HIV counselling and testing study in KwaZulu-Natal, South Africa between November 2011 and June 2012. Contiguous households were approached and all adults ≥18 years old were offered an HIV test...
October 2017: Journal of the International AIDS Society
https://www.readbyqxmd.com/read/29062573/increased-susceptibility-of-post-weaning-rats-on-high-fat-diet-to-metabolic-syndrome
#18
Hong Sheng Cheng, So Ha Ton, Sonia Chew Wen Phang, Joash Ban Lee Tan, Khalid Abdul Kadir
The present study aimed to examine the effects of the types of high-calorie diets (high-fat and high-fat-high-sucrose diets) and two different developmental stages (post-weaning and young adult) on the induction of metabolic syndrome. Male, post-weaning and adult (3- and 8-week old, respectively) Sprague Dawley rats were given control, high-fat (60% kcal), and high-fat-high-sucrose (60% kcal fat + 30% sucrose water) diets for eight weeks (n = 6 to 7 per group). Physical, biochemical, and transcriptional changes as well as liver histology were noted...
November 2017: Journal of Advanced Research
https://www.readbyqxmd.com/read/29055048/adolescent-obesity-and-adult-male-breast-cancer-in-a-cohort-of-1-382-093-men
#19
Lital Keinan-Boker, Hagai Levine, Adi Leiba, Estela Derazne, Jeremy D Kark
Male breast cancer (MBC) accounts for 1% of all breast cancer. Adult obesity and tallness are risk factors for MBC, but the role of adolescent fatness is largely unknown. We aimed to assess the association between body mass index (BMI) in adolescence and the incidence of MBC in a large cohort of 16-19 year-old Israeli males. 1,382,093 Jewish Israeli males aged 16-19 who underwent anthropometric measurements, a General Intelligence Test (GIT) and other examinations during 1967-2011, were followed up to 31.12...
October 21, 2017: International Journal of Cancer. Journal International du Cancer
https://www.readbyqxmd.com/read/29054808/high-amylose-starch-consumption-induces-obesity-in-drosophila-melanogaster-and-metformin-partially-prevents-accumulation-of-storage-lipids-and-shortens-lifespan-of-the-insects
#20
Oleksandra B Abrat, Janet M Storey, Kenneth B Storey, Volodymyr I Lushchak
There are very few studies that have directly analyzed the effects of dietary intake of slowly digestible starches on metabolic parameters of animals. The present study examined the effects of slowly digestible starch with high amylose content (referred also as amylose starch) either alone, or in combination with metformin on the development, lifespan, and levels of glucose and storage lipids in the fruit fly Drosophila melanogaster. Consumption of amylose starch in concentrations 0.25-10% did not affect D...
October 18, 2017: Comparative Biochemistry and Physiology. Part A, Molecular & Integrative Physiology
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