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Diabetes adult compliance

Viswanathan Mohan, Sunil Jain, Jothydev Kesavadev, Manoj Chawla, Abhay Mutha, Vijay Viswanathan, Banshi Saboo, Rajiv Kovil, Ambrish Mithal, Dharmen Punatar, John Shin
BACKGROUND: Retrospective continuous glucose monitoring (CGM) studies may provide healthcare professionals (HCPs) with better understanding of glycemic patterns in patients with type 2 diabetes (T2D) and thereby support patient education and appropriate therapeutic interventions. METHODS: Adults with T2D and A1C values between 8% and 10% were eligible for this 3-month study. Patients were scheduled for 5 visits that included baseline and a month-2 retrospective CGM study (iPro2, Medtronic) followed by data review and therapy modifications...
April 2016: Journal of the Association of Physicians of India
Christy Foster, Jayne Bellando, Yu-Chi Annie Wang
Type 1 diabetes is a chronic disease that can lead to severe complications if poorly controlled. Adolescents are particularly vulnerable to worsening diabetes control due to changes in physiology, family dynamics, and social interactions. Good diabetes control requires following a regimen of frequent blood glucose checks, accurate carbohydrate counts, and compliance with insulin administration. Patients who are challenged in controlling their diabetes do tend to respond to behavioral interventions; however, the effect of the intervention wanes over time...
September 1, 2016: Pediatric Annals
George Dailey, Aakif Ahmad, Sarit Polsky, Viral Shah
Many adults with type 2 diabetes (T2D) do not achieve or maintain glycemic targets on oral antidiabetes drugs (OADs) alone and require insulin therapy. Although initiating basal insulin is common when treatment needs to be intensified, individualization of therapy (in line with current guidelines) may lead more health care professionals (HCPs) to add rapid-acting insulin (RAI) to OAD regimens for treatment of postprandial hyperglycemia to achieve glycated hemoglobin (A1C) targets. HCPs and patients are concerned about the burden associated with injections...
August 31, 2016: Postgraduate Medicine
Philip M S Evans, Stephen C Bain
INTRODUCTION: The estimated global prevalence of diabetes mellitus for adults aged 20-70 in 2015 was 415 million with approximately 90% of diagnosed cases being Type 2 diabetes mellitus (T2DM). Improvements in lifestyle and effective therapies are key to management but due to the progressive nature of T2DM, pharmacotherapy is typically required. Whilst the initial therapy will usually be with metformin, thereafter treatment should be individualised, with consideration of several different second line options...
October 2016: Expert Opinion on Pharmacotherapy
Christina Mtuya, Charles R Cleland, Heiko Philippin, Kidayi Paulo, Bernard Njau, William U Makupa, Claudette Hall, Anthony Hall, Paul Courtright, Declare Mushi
BACKGROUND: Diabetes is an emerging public health problem in sub-Saharan Africa. Diabetic retinopathy is the commonest microvascular complication of diabetes and is a leading cause of blindness, mainly in adults of working age. Follow-up is crucial to the effective management of diabetic retinopathy, however, follow-up rates are often poor in sub-Saharan Africa. The aim of this study was to assess the proportion of patients not presenting for follow-up and the reasons for poor follow-up of diabetic patients after screening for retinopathy in Kilimanjaro Region of Tanzania...
2016: BMC Ophthalmology
Katherine Grunzweig, Bala G Nair, Gene N Peterson, Mayumi Horibe, Moni B Neradilek, Shu-Fang Newman, Gail Van Norman, Howard A Schwid, Wei Hao, E Patchen Dellinger, Irl B Hirsch
OBJECTIVE: To understand the decisional practices of anesthesia providers in managing intraoperative glucose levels. DESIGN: This is a retrospective cohort study. SETTING: Operating rooms in an academic medical center. PATIENTS: Adult patients undergoing surgery. INTERVENTION: Intraoperative blood glucose management based on an institutional protocol. MEASUREMENTS: Glucose management data was extracted from electronic medical records to determine compliance to institutional glucose management protocol that prescribes hourly glucose measurements and insulin doses to maintain glucose levels between 100 to 140mg/dL...
August 2016: Journal of Clinical Anesthesia
Arijit Ghosh, Pranab Kumar Sahana, Chanchal Das, Ananya Mandal, Nilanjan Sengupta
INTRODUCTION: Diabetic dyslipidaemia poses a therapeutic challenge. New therapies have emerged in this patient subgroup to enhance outcome and improve compliance. AIM: The aim of this study was to compare the effectiveness and safety of add on therapy of saroglitazar and fenofibrate with metformin in Indian patients with diabetic dyslipidaemia. MATERIALS AND METHODS: Adults patients with diabetic dyslipidaemia fulfilling the inclusion criteria were randomized in two groups...
March 2016: Journal of Clinical and Diagnostic Research: JCDR
S K Kunutsor, S Seidu, K Khunti
AIMS: To evaluate the benefits and harms of aspirin for the primary prevention of cardiovascular disease and all-cause mortality events in people with diabetes by conducting a systematic review and meta-analysis. METHODS: Randomized controlled trials of aspirin compared with placebo (or no treatment) in people with diabetes with no history of cardiovascular disease were identified from MEDLINE, EMBASE, Web of Science, the Cochrane Library and a manual search of bibliographies to November 2015...
April 17, 2016: Diabetic Medicine: a Journal of the British Diabetic Association
Ramon Vilallonga, Jacques Himpens, Simon van de Vrande
BACKGROUND: Few data are available about obesity surgery in adolescent patients. OBJECTIVE: To assess long-term outcomes after laparoscopic Roux-en-Y gastric bypass (LRYGB) in patients <18 years. SETTING: University Hospital, Europe. METHODS: A retrospective study of prospectively collected data of patients <18 years (childhood group; ChG) (n = 28) treated by LRYGB of which 19 were available for follow-up between 2...
2016: Obesity Facts
Anne Munck, Corinne Alberti, Carla Colombo, Nataliya Kashirskaya, Helmut Ellemunter, Maria Fotoulaki, Roderick Houwen, Eddy Robberecht, Priscilla Boizeau, Michael Wilschanski
BACKGROUND: Distal intestinal obstruction syndrome (DIOS) is a specific complication of cystic fibrosis. METHODS: A study was performed in 10 countries to prospectively evaluate the incidence, associated factors, and treatment modalities in children and adults. RESULTS: 102 patients presented 112 episodes. The incidence of DIOS was similar in children and adults. Medical treatment failed only in cases of complete DIOS (11%). Children with meconium ileus had a higher rate of surgery for DIOS (15% vs...
July 2016: Journal of Cystic Fibrosis: Official Journal of the European Cystic Fibrosis Society
Faiza Qari
OBJECTIVES: The aims of this study were assessing the frequency of clinical characteristics of patients with severe Diabetic ketoacidosis (DKA) who were admitted to the intensive care unit (ICU) and investigating the relationship between paraclinical (glucose, anion gap, and serum bicarbonate) and clinical parameters in patients with severe DKA. METHOD: A retrospective chart review of all adult patients with DKA who were admitted to the ICU at King Abdulaziz University Hospital, Jeddah, Saudi Arabia between January 2012 and December 2013...
November 2015: Pakistan Journal of Medical Sciences Quarterly
Carlos A Andrade-Castellanos, Luis Enrique Colunga-Lozano, Netzahualpilli Delgado-Figueroa, Daniel A Gonzalez-Padilla
BACKGROUND: Diabetic ketoacidosis (DKA) is an acute, life-threatening complication of uncontrolled diabetes that mainly occurs in individuals with autoimmune type 1 diabetes, but it is not uncommon in some people with type 2 diabetes. The treatment of DKA is traditionally accomplished by the administration of intravenous infusion of regular insulin that is initiated in the emergency department and continued in an intensive care unit or a high-dependency unit environment. It is unclear whether people with DKA should be treated with other treatment modalities such as subcutaneous rapid-acting insulin analogues...
January 21, 2016: Cochrane Database of Systematic Reviews
Belén Moreno-Franco, José L Peñalvo, José A Casasnovas Lenguas, Montserrat Leon-Latre
BACKGROUND: Physical inactivity remains a public health problem worldwide. The purpose of this study was to determine compliance with physical activity (PA) recommendations developed by the World Health Organization (WHO) and to analyze the association with different cardiovascular risk factors (CVRF) and sociodemographic and lifestyle determinants in a sample of Spanish workers. METHODS: A cross sectional analysis was carried out in a sample of 2.651 individuals (2...
October 2015: Revista Española de Salud Pública
Ho-Seong Jin, Ah-Reum An, Ho-Chun Choi, Sang-Hyun Lee, Dong-Heon Shin, Seung-Min Oh, Young-Gyun Seo, Be-Long Cho
BACKGROUND: Proper physical activities are known to be helpful in the prevention and management of chronic diseases. However, the physical activity level of patients with chronic diseases is low. Therefore, this study aimed to investigate the physical activity compliance of patients with hypertension, diabetes, and dyslipidemia in Korea. METHODS: This study analyzed the 2010-2012 Fifth Korean National Health and Nutrition Examination Survey data. We included 13,873 individuals in the analysis...
November 2015: Korean Journal of Family Medicine
Nicholas Fusco, Jeffrey Gonzales, Siu Yan Amy Yeung
OBJECTIVE: To determine if treatment of DKA in a sample of adult medical intensive care unit (MICU) patients was consistent with the 2006 ADA Hyperglycemic Crises in Adult Patients with Diabetes Clinical Guidelines. METHODS: Medical records were reviewed for all adult patients admitted to a MICU with a diagnosis of DKA between July 1, 2007 and June 30, 2010. The primary composite endpoint assessed fluid resuscitation (total mL/kg) at 24 hours, insulin bolus dose, and continuous insulin infusion (units/kg or units/kg/hour) to determine whether the 2006 ADA clinical guidelines for Hyperglycemic Crises in Adult Patients with Diabetes were followed...
December 1, 2015: American Journal of Health-system Pharmacy: AJHP
Liz Gardner, Glenn Leshner
This study charts pathways through message resistance to enhance the persuasiveness of diabetes self-care messages. A 2 (narrative) × 2 (other-referencing) × 2 (message) × 4 (order) experiment with adult diabetics (N = 58) tested whether packaging overt recommendations as a story rather than an informational argument (i.e., narrative structure) and highlighting the impact of health decisions on family and friends rather than the individual (i.e., other-referencing) can effectively attenuate psychological reactance to messages encouraging healthy diet and physical activity...
2016: Health Communication
Marcin Czech, Elżbieta Rdzanek, Justyna Pawęska, Olga Adamowicz-Sidor, Maciej Niewada, Michał Jakubczyk
BACKGROUND: Diabetes mellitus (DM) leads to multiple complications, including severe hypoglycaemia events (SHEs). SHEs can impact a patient's quality of life and compliance and may directly result in additional costs to the health care system. The aim of this review was to evaluate the risk of severe hypoglycaemia in patients with type 1 (T1) and 2 (T2) DM as observed in everyday clinical practice for various drug regimens. METHODS: We conducted a systematic review of observational (retrospective or prospective) studies in the MEDLINE, Embase, and Cochrane Library databases that covered at least 100 children or adults with T1/T2 DM...
2015: BMC Endocrine Disorders
Rajajeyakumar Manivel, Pirabhu Ravanan, Chenniappan Meenakshisundram, Niranjana Dhanaprakasam, Sivan Arul Selvan Sundramoorthy, Sushmita Sreekumar, Janitha Alagarsamy, Arun Amaladass
INTRODUCTION: Normal vascular is associated with gradual change of vascular structure and function, resulting in increased arterial stiffening and decreased arterial compliance. Arterial stiffness is a marker of vascular ageing and a predictor of cardiovascular events. Premature or early vascular ageing is measured by pulse wave velocity or the arterial augmentation index based on pulse wave analysis. AIM: To study the predictor of vascular dysfunctions in high risk young adult offsprings of type 2 diabetes mellitus and hypertensive parents...
July 2015: Journal of Clinical and Diagnostic Research: JCDR
Ayeesha Kamran Kamal, Quratulain Nauman Shaikh, Omrana Pasha, Iqbal Azam, Muhammad Islam, Adeel Ali Memon, Hasan Rehman, Muhammad Affan, Sumaira Nazir, Salman Aziz, Muhammad Jan, Anita Andani, Abdul Muqeet, Bilal Ahmed, Shariq Khoja
BACKGROUND: Stroke is a major cause of morbidity and mortality, especially in low and middle income countries. Medical management is the mainstay of therapy to prevent recurrence of stroke. Current estimates are that only 1 in 6 patients have perfect adherence to medication schedules. Using SMS (Short Messaging Service) as reminders to take medicines have been used previously for diseases such as diabetes and HIV with moderate success. We aim to explore the effectiveness and acceptability of SMS in increasing adherence to medications in patients with stroke...
2015: BMC Neurology
Brandy Wicklow, Kristy Wittmeier, Geert W T' Jong, Jonathon McGavock, Marni Robert, Todd Duhamel, Vernon W Dolinsky
Non-alcoholic fatty liver (NAFL) disease (NAFLD) affects 30% of overweight adolescents and increases the risk of type 2 diabetes mellitus (T2D). Resveratrol is a naturally occurring compound with potential to reverse NAFL and its associated insulin resistance in adults. The use of resveratrol to reduce risk for T2D through its effect on NAFL has not been examined to date in youth. This paper provides a literature review and protocol for a 30 day proof of principle trial of resveratrol in a population of adolescents at risk for T2D...
October 2015: Biochemistry and Cell Biology, Biochimie et Biologie Cellulaire
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