Meagan L Collins Hutchinson, Judith St-Onge, Sabrina Schlienger, Nassima Boudrahem-Addour, Lina Mougharbel, Jean-Francois Michaud, Clara Lloyd, Elena Bruneau, Cedric Roux, Ahmed N Sahly, Bradley Osterman, Kenneth A Myers, Guy A Rouleau, Daniel Alexander Jimenez Cruz, Jean-Baptiste Rivière, Andrea Accogli, Frederic Charron, Myriam Srour
BACKGROUND: Congenital mirror movements (CMM) is a rare neurodevelopmental disorder characterized by involuntary movements from one side of the body that mirror voluntary movements on the opposite side. To date, five genes have been associated with CMM, namely DCC, RAD51, NTN1, ARHGEF7, and DNAL4. OBJECTIVE: The aim of this study is to characterize the genetic landscape of CMM in a large group of 80 affected individuals. METHODS: We screened 80 individuals with CMM from 43 families for pathogenic variants in CMM genes...
February 2024: Movement Disorders: Official Journal of the Movement Disorder Society