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https://www.readbyqxmd.com/read/28212295/short-chain-chitin-oligomers-promoters-of-plant-growth
#1
Alexander J Winkler, Jose Alfonso Dominguez-Nuñez, Inmaculada Aranaz, César Poza-Carrión, Katrina Ramonell, Shauna Somerville, Marta Berrocal-Lobo
Chitin is the second most abundant biopolymer in nature after cellulose, and it forms an integral part of insect exoskeletons, crustacean shells, krill and the cell walls of fungal spores, where it is present as a high-molecular-weight molecule. In this study, we showed that a chitin oligosaccharide of lower molecular weight (tetramer) induced genes in Arabidopsis that are principally related to vegetative growth, development and carbon and nitrogen metabolism. Based on plant responses to this chitin tetramer, a low-molecular-weight chitin mix (CHL) enriched to 92% with dimers (2mer), trimers (3mer) and tetramers (4mer) was produced for potential use in biotechnological processes...
February 15, 2017: Marine Drugs
https://www.readbyqxmd.com/read/28202036/kinesthetic-deficits-after-perinatal-stroke-robotic-measurement-in-hemiparetic-children
#2
Andrea M Kuczynski, Jennifer A Semrau, Adam Kirton, Sean P Dukelow
BACKGROUND: While sensory dysfunction is common in children with hemiparetic cerebral palsy (CP) secondary to perinatal stroke, it is an understudied contributor to disability with limited objective measurement tools. Robotic technology offers the potential to objectively measure complex sensorimotor function but has been understudied in perinatal stroke. The present study aimed to quantify kinesthetic deficits in hemiparetic children with perinatal stroke and determine their association with clinical function...
February 15, 2017: Journal of Neuroengineering and Rehabilitation
https://www.readbyqxmd.com/read/28185638/exoskeleton-assisted-walking-for-people-with-spinal-cord-injury
#3
Paula Richley Geigle, Marni Kallins
No abstract text is available yet for this article.
February 6, 2017: Archives of Physical Medicine and Rehabilitation
https://www.readbyqxmd.com/read/28176425/sensory-tractography-and-robot-quantified-proprioception-in-hemiparetic-children-with-perinatal-stroke
#4
Andrea M Kuczynski, Helen L Carlson, Catherine Lebel, Jacquie A Hodge, Sean P Dukelow, Jennifer A Semrau, Adam Kirton
Perinatal stroke causes most hemiparetic cerebral palsy, resulting in lifelong disability. We have demonstrated the ability of robots to quantify sensory dysfunction in hemiparetic children but the relationship between such deficits and sensory tract structural connectivity has not been explored. It was aimed to characterize the relationship between the dorsal column medial lemniscus (DCML) pathway connectivity and proprioceptive dysfunction in children with perinatal stroke. Twenty-nine participants (6-19 years old) with MRI-classified, unilateral perinatal ischemic stroke (14 arterial, 15 venous), and upper extremity deficits were recruited from a population-based cohort and compared with 21 healthy controls...
February 8, 2017: Human Brain Mapping
https://www.readbyqxmd.com/read/28149685/size-matters-relationships-between-body-size-and-body-mass-of-common-coastal-aquatic-invertebrates-in-the-baltic-sea
#5
Johan Eklöf, Åsa Austin, Ulf Bergström, Serena Donadi, Britas D H K Eriksson, Joakim Hansen, Göran Sundblad
BACKGROUND: Organism biomass is one of the most important variables in ecological studies, making biomass estimations one of the most common laboratory tasks. Biomass of small macroinvertebrates is usually estimated as dry mass or ash-free dry mass (hereafter 'DM' vs. 'AFDM') per sample; a laborious and time consuming process, that often can be speeded up using easily measured and reliable proxy variables like body size or wet (fresh) mass. Another common way of estimating AFDM (one of the most accurate but also time-consuming estimates of biologically active tissue mass) is the use of AFDM/DM ratios as conversion factors...
2017: PeerJ
https://www.readbyqxmd.com/read/28141525/e-o-a-brain-controlled-lower-limb-exoskeleton-for-rhesus-macaques
#6
Tristan Vouga, Katie Zhuang, Jeremy Olivier, Mikhail Lebedev, Miguel Nicolelis, Mohamed Bouri, Hannes Bleuler
Recent advances in the field of brain-machine interfaces (BMIs) have demonstrated enormous potential to shape the future of rehabilitation and prosthetic devices. Here, a lower-limb exoskeleton controlled by the intracortical activity of an awake, behaving rhesus macaque is presented as a proof-of-concept for a locomotor BMI. A detailed description of the mechanical device, including its innovative features and first experimental results, is provided. During operation, BMI-decoded position and velocity are directly mapped onto the bipedal exoskeleton's motions, which then move the monkey's legs as the monkey remains physically passive...
January 26, 2017: IEEE Transactions on Neural Systems and Rehabilitation Engineering
https://www.readbyqxmd.com/read/28120076/reability-complex-external-prosthesis-systems-to-rehabilitate-movement
#7
Bice Previtera, Carlo Jovine, Massimiliano Visocchi
The ReAbility Project is a solution that provides an alternative to wheelchair mobility for people with serious disabilities of the lower limbs, such as paraplegics, allowing them to stand and walk once again. This solution is achieved by utilizing an instrument called an "exoskeleton".The ReAbility device is a robotic-assisted system designed to improve the quality of life of people with a movement disability and/or reduced movement; it is meant both for daily domestic use and for rehabilitation therapy in hospitals and rehabilitation centers...
2017: Acta Neurochirurgica. Supplement
https://www.readbyqxmd.com/read/28118698/wearable-robotic-exoskeleton-for-over-ground-gait-training-in-sub-acute-and-chronic-hemiparetic-stroke-patients-preliminary-results
#8
Franco Molteni, Giulio Gasperini, Marina Gaffuri, Maria Colombo, Chiara Giovanzana, Chiara Lorenzon, Nico Farina, Giovanni Cannaviello, Stefano Scarano, Davide Proserpio, Davide Liberali, Eleonora Guanziroli
BACKGROUND: Recovery of therapeutic or functional ambulatory capacity in post-stroke patients is a primary goal of rehabilitation. Wearable powered exoskeletons allow patients with gait dysfunctions to perform over-ground gait training, even immediately after the acute event. AIM: To investigate the feasibility and the clinical effects of an over-ground walking training with a wearable powered exoskeleton in sub-acute and chronic stroke patients. DESIGN: Prospective, pilot pre-post, open label, non-randomized experimental study...
24, 2017: European Journal of Physical and Rehabilitation Medicine
https://www.readbyqxmd.com/read/28114023/training-the-unimpaired-arm-improves-the-motion-of-the-impaired-arm-and-the-sitting-balance-in-chronic-stroke-survivors
#9
Alice De Luca, Psiche Giannoni, Honore Vernetti, Cristina Capra, Cinzia Cassiano, Luca Loguercio, Ivano Pisu, Federica Gaito, Laura Barone, Rosaria Carioti, Carmelo Lentino, Giovanni Checchia, Maura Casadio
Robot-assisted rehabilitation of stroke survivors mainly focuses on the impaired side of the body while the role of the unimpaired side in the recovery after stroke is still controversial. The goal of this study is to investigate the influence on sitting balance and paretic arm functions of a training protocol based on movements of the unimpaired arm. Sixteen chronic stroke survivors underwent nineteen training sessions, in which they performed active movements with the unimpaired arm supported by a passive exoskeleton...
December 5, 2016: IEEE Transactions on Neural Systems and Rehabilitation Engineering
https://www.readbyqxmd.com/read/28113858/rehabilitative-soft-exoskeleton-for-rodents
#10
Juan Manuel Florez, Manan Shah, Eduardo Martin Moraud, Sophie Wurth, Laetitia Baud, Joachim von Zitzewitz, Rubia Van Den Brand, Silvestro Micera, Gregoire Courtine, Jamie Paik
Robotic exoskeletons provide programmable, consistent and controllable active therapeutic assistance to patients with neurological disorders. Here we introduce a prototype and preliminary experimental evaluation of a rehabilitative gait exoskeleton that enables compliant yet effective manipulation of the fragile limbs of rats. To assist the displacements of the lower limbs without impeding natural gait movements, we designed and fabricated soft pneumatic actuators (SPAs). The exoskeleton integrates two customizable SPAs that are attached to a limb...
March 18, 2016: IEEE Transactions on Neural Systems and Rehabilitation Engineering
https://www.readbyqxmd.com/read/28113200/design-and-characterization-of-an-exoskeleton-for-perturbing-the-knee-during-gait
#11
Michael R Tucker, Camila Shirota, Olivier Lambercy, James Sulzer, Roger Gassert
OBJECTIVE: An improved understanding of mechanical impedance modulation in human joints would provide insights about the neuromechanics underlying functional movements. Experimental estimation of impedance requires specialized tools with highly reproducible perturbation dynamics and reliable measurement capabilities. This paper presents the design and mechanical characterization of the ETH Knee Perturbator: an actuated exoskeleton for perturbing the knee during gait. METHODS: A novel wearable perturbation device was developed based on specific experimental objectives...
January 20, 2017: IEEE Transactions on Bio-medical Engineering
https://www.readbyqxmd.com/read/28108003/active-disturbance-rejection-control-based-human-gait-tracking-for-lower-extremity-rehabilitation-exoskeleton
#12
Yi Long, Zhijiang Du, Lin Cong, Weidong Wang, Zhiming Zhang, Wei Dong
This paper presents an active disturbance rejection control (ADRC) based strategy, which is applied to track the human gait trajectory for a lower limb rehabilitation exoskeleton. The desired human gait trajectory is derived from the Clinical Gait Analysis (CGA). In ADRC, the total external disturbance can be estimated by the extended state observer (ESO) and canceled by the designed control law. The observer bandwidth and the controller bandwidth are determined by the practical principles. We simulated the proposed methodology in MATLAB...
January 17, 2017: ISA Transactions
https://www.readbyqxmd.com/read/28094764/neuromorphic-meets-neuromechanics-part-ii-the-role-of-fusimotor-drive
#13
Kian Jalaleddini, Chuanxin Minos Niu, Suraj Chakravarthi Raja, Won Joon Sohn, Gerald E Loeb, Terence D Sanger, Francisco J Valero-Cuevas
OBJECTIVE: We studied the fundamentals of muscle afferentation by building a Neuro-mechano-morphic system actuating a cadaveric finger. This system is a faithful implementation of the stretch reflex circuitry. It allowed the systematic exploration of the effects of different fusimotor drives to the muscle spindle on the closed-loop stretch reflex response. APPROACH: As in Part I of this work, sensory neurons conveyed proprioceptive information from muscle spindles (with static and dynamic fusimotor drive) to populations of α-motor neurons (with recruitment and rate coding properties)...
January 17, 2017: Journal of Neural Engineering
https://www.readbyqxmd.com/read/28093370/a-comparison-of-locomotor-therapy-interventions-partial-body-weight-supported-treadmill-lokomat%C3%A2-and-g-eo%C3%A2-training-in-persons-with-traumatic-brain-injury
#14
Alberto Esquenazi, Stella Lee, Amanda Wikoff, Andrew Packel, Theresa Toczylowski, John Feeley
BACKGROUND: Literature in the application of gait training techniques in persons with traumatic brain injury is limited. Current techniques require of multiple staff and are physically demanding. The use of a robotic locomotor training may provide improved training capacity for this population. OBJECTIVE: To examine the impact of three different modes of locomotor therapy on gait velocity and spatiotemporal symmetry using: an end effector robot (G-EO™); a robotic exoskeleton (Lokomat®) and manual assisted partial-body weight supported treadmill training (PBWSTT) in participants with traumatic brain injury...
January 13, 2017: PM & R: the Journal of Injury, Function, and Rehabilitation
https://www.readbyqxmd.com/read/28092566/wake-up-exoskeleton-to-assist-children-with-cerebral-palsy-design-and-preliminary-evaluation-in-level-walking
#15
Fabrizio Patane, Stefano Rossi, Fausto Del Sette, Juri Taborri, Paolo Cappa
This paper presents the modular design and control of a novel compliant lower limb multi-joint exoskeleton for the rehabilitation of ankle knee mobility and locomotion of pediatric patients with neurological diseases, such as Cerebral Palsy (CP). The device consists of an untethered powered knee-ankle-foot orthosis (KAFO), addressed as WAKE-up (Wearable Ankle Knee Exoskeleton), characterized by a position control and capable of operating synchronously and synergistically with the human musculoskeletal system...
January 11, 2017: IEEE Transactions on Neural Systems and Rehabilitation Engineering
https://www.readbyqxmd.com/read/28079030/neuromusculoskeletal-model-self-calibration-for-on-line-sequential-bayesian-moment-estimation
#16
Diana Ruiz Bueno, Luis Montano
OBJECTIVE: Neuromusculoskeletal models involve many subject-specific physiological parameters that need to be adjusted to adequately represent muscle properties. Traditionally, neuromusculoskeletal models have been calibrated with a forward-inverse dynamic optimization which is time-consuming and unfeasible for rehabilitation therapy. Non self-calibration algorithms have been applied to these models. To the best of our knowledge, the algorithm proposed in this work is the first on-line calibration algorithm for muscle models that allows a generic model to be adjusted to different subjects in a few steps...
January 12, 2017: Journal of Neural Engineering
https://www.readbyqxmd.com/read/28076454/a-broad-ph-range-and-processive-chitinase-from-a-metagenome-library
#17
S S Thimoteo, A Glogauer, H Faoro, E M de Souza, L F Huergo, B M Moerschbacher, F O Pedrosa
Chitinases are hydrolases that degrade chitin, a polymer of N-acetylglucosamine linked β(1-4) present in the exoskeleton of crustaceans, insects, nematodes and fungal cell walls. A metagenome fosmid library from a wastewater-contaminated soil was functionally screened for chitinase activity leading to the isolation and identification of a chitinase gene named metachi18A. The metachi18A gene was subcloned and overexpressed in Escherichia coli BL21 and the MetaChi18A chitinase was purified by affinity chromatography as a 6xHis-tagged fusion protein...
January 5, 2017: Brazilian Journal of Medical and Biological Research, Revista Brasileira de Pesquisas Médicas e Biológicas
https://www.readbyqxmd.com/read/28076349/mechanical-control-of-whole-body-shape-by-a-single-cuticular-protein-obstructor-e-in-drosophila-melanogaster
#18
Reiko Tajiri, Nobuhiro Ogawa, Haruhiko Fujiwara, Tetsuya Kojima
Body shapes are much more variable than body plans. One way to alter body shapes independently of body plans would be to mechanically deform bodies. To what extent body shapes are regulated physically, or molecules involved in physical control of morphogenesis, remain elusive. During fly metamorphosis, the cuticle (exoskeleton) covering the larval body contracts longitudinally and expands laterally to become the ellipsoidal pupal case (puparium). Here we show that Drosophila melanogaster Obstructor-E (Obst-E) is a protein constituent of the larval cuticle that confers the oriented contractility/expandability...
January 2017: PLoS Genetics
https://www.readbyqxmd.com/read/28074858/traces-of-an-ancient-immune-system-how-an-injured-arthropod-survived-465-million-years-ago
#19
Brigitte Schoenemann, Euan N K Clarkson, Magne Høyberget
This report of a severely injured trilobite from the Middle Ordovician (~465 Ma) accords with a number of similar observations of healed lesions observed in trilobites. The uniqueness of the specimen described here is that the character of the repair-mechanisms is reflected by the secondarily built structures, which form the new surface of the ruptured compound eye. Smooth, repaired areas inside the visual surface advert to a clotting principle, rather similar to those of today, and the way in which broken parts of the exoskeleton fused during restoration seem to simulate modern samples...
January 11, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28071705/digestive-and-appendicular-soft-parts-with-behavioural-implications-in-a-large-ordovician-trilobite-from-the-fezouata-lagerst%C3%A3-tte-morocco
#20
Juan C Gutiérrez-Marco, Diego C García-Bellido, Isabel Rábano, Artur A Sá
Trilobites were one of the most successful groups of marine arthropods during the Palaeozoic era, yet their soft-part anatomy is only known from a few exceptionally-preserved specimens found in a handful of localities from the Cambrian to the Devonian. This is because, even if the sclerotized appendages were not destroyed during early taphonomic stages, they are often overprinted by the three-dimensional, mineralised exoskeleton. Inferences about the ventral anatomy and behavioural activities of trilobites can also be derived from the ichnological record, which suggests that most Cruziana and Rusophycus trace fossils were possibly produced by the actions of trilobites...
January 10, 2017: Scientific Reports
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