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https://www.readbyqxmd.com/read/28423476/dietary-patterns-and-alcohol-consumption-during-pregnancy-secondary-analysis-of-avon-longitudinal-study-of-parents-and-children
#1
Victoria Coathup, Kate Northstone, Ron Gray, Simon Wheeler, Lesley Smith
BACKGROUND: Large general population surveys show that heavy regular and episodic alcohol consumption are associated with lower intakes of fruits and vegetables, and higher intakes of processed and fried meat. This is of particular concern regarding pregnant women, as both alcohol intake and inadequate maternal nutrition are independently associated with adverse fetal outcomes. The current study aimed to determine associations between maternal dietary patterns and alcohol consumption during pregnancy...
April 19, 2017: Alcoholism, Clinical and Experimental Research
https://www.readbyqxmd.com/read/28419567/cardiorespiratory-physiology-in-the-safe-passage-study-protocol-methods-and-normative-values-in-unexposed-infants
#2
Michael M Myers, Amy J Elliott, Hein J Odendaal, Larry Burd, Jyoti Angal, Coen Groenewald, J David Nugent, Joel S Yang, Joseph R Isler, Kim A Dukes, Fay Robinson, William P Fifer
AIM: The Safe Passage Study, conducted by the Prenatal Alcohol in SIDS and Stillbirth Network, is investigating contributions of prenatal alcohol exposure to fetal and infant demise. This current report presents physiological data from full term infants with no prenatal exposure to alcohol or maternal smoking. METHODS: Data are from 666 infants from the Northern Plains (North and South Dakota) and South Africa. A standardized protocol assessed cardiorespiratory function during baseline and head-up tilts shortly after birth and at 1 month of age...
April 17, 2017: Acta Paediatrica
https://www.readbyqxmd.com/read/28417285/alcohol-and-thiamine-deficiency-trigger-differential-mitochondrial-transition-pore-opening-mediating-cellular-death
#3
REVIEW
Abdoulaye Bâ
Accumulating evidence has shown that binge-type alcohol intake in mothers interferes with thiamine deficiency (TD) to promote the fetal alcohol syndrome (FAS). Developmental alcohol or TD exposures act either synergistically or separately to reproduce FAS features e.g. intrauterine growth retardation and related microcephaly characterized by extensive cellular death induced by one another neurotoxicant. However molecular and cellular mechanisms underlying apoptosis in both alcohol and TD toxicities are unknown...
April 17, 2017: Apoptosis: An International Journal on Programmed Cell Death
https://www.readbyqxmd.com/read/28413697/acute-ethanol-exposure-during-late-mouse-neurodevelopment-results-in-long-term-deficits-in-memory-retrieval-but-not-in-social-responsiveness
#4
Katherine Houlé, Myshake Abdi, Erin B D Clabough
OBJECTIVE: Prenatal alcohol exposure can result in neurological changes in affected individuals and may result in the emergence of a broad spectrum of neurobehavioral abnormalities termed fetal alcohol spectrum disorders (FASD). The effects of ethanol exposure during development are both time and dose dependent. Although many animal models of FASD use more chronic ethanol exposure, acute developmental alcohol exposure may also cause long-lasting neuronal changes. Our research employed behavioral measures to assess the effects of a single early postnatal ethanol intoxication event in mice...
April 2017: Brain and Behavior
https://www.readbyqxmd.com/read/28401132/comparing-diagnostic-classification-of-neurobehavioral-disorder-associated-with-prenatal-alcohol-exposure-with-the-canadian-fetal-alcohol-spectrum-disorder-guidelines-a-cohort-study
#5
James L Sanders, Rebecca E Hudson Breen, Nicole Netelenbos
BACKGROUND: Diagnostic criteria have recently been introduced in the Diagnostic and Statistical Manual of Mental Disorders, 5th edition (DSM-5), for neurobehavioral disorder associated with prenatal alcohol exposure (ND-PAE). The purpose of this study is to assess the classification of this condition using the Canadian fetal alcohol spectrum disorder (FASD) multidisciplinary diagnostic guidelines as the standard of comparison. First, classification of ND-PAE was compared with Canadian FASD diagnoses of fetal alcohol syndrome (FAS), partial FAS and alcohol-related neurodevelopmental disorder...
January 2017: CMAJ Open
https://www.readbyqxmd.com/read/28381366/nocturnal-incontinence-in-children-with-fetal-alcohol-spectrum-disorders-fasd-in-a-south-african-cohort
#6
Sylvia Roozen, Leana Olivier, Justine Niemczyk, Alexander von Gontard, Gjalt-Jorn Y Peters, Gerjo Kok, Denis Viljoen, Leopold Curfs
INTRODUCTION: Fetal alcohol spectrum disorders (FASD) are one of the leading preventable causes of intellectual disabilities (ID). Not much is known about the topic of pediatric incontinence related to FASD, for example nocturnal enuresis (NE), daytime urinary incontinence (DUI), and fecal incontinence (FI). So far, incontinence problems have been examined among children with other specific syndromes. OBJECTIVE: The aim of the present study is to investigate the possible presence of incontinence among children with FASD in a South African cohort...
March 23, 2017: Journal of Pediatric Urology
https://www.readbyqxmd.com/read/28370022/the-public-stigma-of-birth-mothers-of-children-with-fetal-alcohol-spectrum-disorders
#7
Patrick W Corrigan, Juana Lorena Lara, Binoy Biren Shah, Kathleen T Mitchell, Diana Simmes, Kenneth L Jones
BACKGROUND: Stigma affects not only the person with a stigmatizing condition such as Fetal Alcohol Spectrum Disorders (FASD), but also their family members. The present study examined whether there are stigmatizing attitudes about biological mothers of children with FASD in a crowdsourced sample. METHODS: Three hundred and eighty-nine participants were asked to rate levels of difference, disdain, and responsibility on four conditions: serious mental illness (SMI), substance use disorder (SUD), jail experience, and FASD...
March 30, 2017: Alcoholism, Clinical and Experimental Research
https://www.readbyqxmd.com/read/28367068/from-scientific-article-to-press-release-to-media-coverage-advocating-alcohol-abstinence-and-democratising-risk-in-a-story-about-alcohol-and-pregnancy
#8
Ellie Lee, Robbie M Sutton, Bonny L Hartley
In this article, we follow the approach taken by Riesch and Spiegalhalter in "Careless pork costs lives': Risk stories from science to press release to media' published in this journal, and offer an assessment of one example of a 'risk story'. Using content and thematic qualitative analysis, we consider how the findings of an article 'Fetal Alcohol Exposure and IQ at Age 8: Evidence from a Population-Based Birth-Cohort Study' were framed in the article itself, the associated press release, and the subsequent extensive media coverage...
August 17, 2016: Health, Risk & Society
https://www.readbyqxmd.com/read/28366413/adverse-effects-of-female-obesity-and-interaction-with-race-on-reproductive-potential
#9
REVIEW
Barbara Luke
Across the reproductive spectrum, obesity is associated with greater risks for adverse health outcomes, including higher rates of infertility, subfertility, early pregnancy loss, fetal deaths and stillbirths, congenital anomalies, and pregnancy complications. The excess reproductive morbidity associated with obesity may increase with longer duration, making the current trends among children and young adults particularly critical in terms of their future reproductive potential. Obese women have a lower chance of pregnancy following in vitro fertilization (IVF), require higher dosages of gonadotropins, and have reduced rates of implantation, clinical intrauterine gestation, and live birth rates and increased rates of pregnancy loss, as well as greater risks for prematurity and preeclampsia even when stratified by plurality...
April 2017: Fertility and Sterility
https://www.readbyqxmd.com/read/28365374/harnessing-neural-stem-cells-for-treating-psychiatric-symptoms-associated-to-fetal-alcohol-spectrum-disorder-and-epilepsy
#10
REVIEW
Trenton Lippert, Lindsey Gelineau, Eleonora Napoli, Cesar V Borlongan
Brain insults with progressive neurodegeneration are inherent in pathological symptoms that represent many psychiatric illnesses. Neural network disruptions characterized by impaired neurogenesis have been recognized to precede, accompany, and possibly even exacerbate the evolution and progression of symptoms of psychiatric disorders. Here, we focus on the neurodegeneration and the resulting psychiatric symptoms observed in fetal alcohol spectrum disorder and epilepsy, in an effort to show that these two diseases are candidate targets for stem cell therapy...
March 29, 2017: Progress in Neuro-psychopharmacology & Biological Psychiatry
https://www.readbyqxmd.com/read/28358798/screening-for-excessive-alcohol-use-and-brief-counseling-of-adults-17-states-and-the-district-of-columbia-2014
#11
Lela R McKnight-Eily, Catherine A Okoro, Roberto Mejia, Clark H Denny, John Higgins-Biddle, Dan Hungerford, Dafna Kanny, Joseph E Sniezek
Excessive and/or risky alcohol use* resulted in $249 billion in economic costs in 2010 (1) and >88,000 deaths in the United States every year from 2006 to 2010 (2). It is associated with birth defects and disabilities (e.g., fetal alcohol spectrum disorders [FASDs]), increases in chronic diseases (e.g., heart disease and breast cancer), and injuries and violence (e.g., motor vehicle crashes, suicide, and homicide).(†) Since 2004, the U.S. Preventive Services Task Force (USPSTF) has recommended alcohol misuse screening and brief counseling (also known as alcohol screening and brief intervention or ASBI) for adults aged ≥18 years (3)...
March 31, 2017: MMWR. Morbidity and Mortality Weekly Report
https://www.readbyqxmd.com/read/28340966/recognition-memory-is-selectively-impaired-in-adult-rats-exposed-to-binge-like-doses-of-ethanol-during-early-postnatal-life
#12
Nicole M MacIlvane, Joseph M Pochiro, Nicole R Hurwitz, Molly J Goodfellow, Derick H Lindquist
Exposure to alcohol in utero can induce a variety of physical and mental impairments, collectively known as fetal alcohol spectrum disorders (FASD). This study explores the persistent cognitive consequences of ethanol administration in rat pups over postnatal days (PD) 4-9, modeling human third trimester consumption. Between PD65-70, ethanol-exposed (5E) and control rats were evaluated in two variants of recognition memory, the spontaneous novel object recognition (NOR) task, using 20 and 240 min sample-to-test delays, and the associative object-in-context (OIC) task, using a 20 min delay...
December 2016: Alcohol
https://www.readbyqxmd.com/read/28334461/profile-of-children-diagnosed-with-a-fetal-alcohol-spectrum-disorder-a-retrospective-chart-review
#13
Natasha Reid, Doug Shelton, Judith Warner, Frances O'Callaghan, Sharon Dawe
INTRODUCTION AND AIMS: Fetal alcohol spectrum disorder (FASD) is a significant public health concern, and growing recognition in Australia led to the establishment of a specialist service for young children. The aim of the current study was to report on the diagnostic profile of a group of children who attended the service, to document the extent to which there were comorbid diagnoses and to provide information on the neurocognitive functioning of the children. DESIGN AND METHODS: This study was a retrospective chart review conducted by the diagnostic service...
March 23, 2017: Drug and Alcohol Review
https://www.readbyqxmd.com/read/28334243/erratum-to-functional-mri-of-human-eyeblink-classical-conditioning-in-children-with-fetal-alcohol-spectrum-disorders
#14
Dominic T Cheng, Ernesta M Meintjes, Mark E Stanton, Neil C Dodge, Mariska Pienaar, Christopher M R Warton, John E Desmond, Christopher D Molteno, Bradley S Peterson, Joseph L Jacobson, Sandra W Jacobson
No abstract text is available yet for this article.
February 25, 2017: Cerebral Cortex
https://www.readbyqxmd.com/read/28326963/the-stillbirth-classification-system-for-the-safe-passage-study
#15
Theonia K Boyd, Colleen A Wright, Hein J Odendaal, Amy J Elliott, Mary Ann Sens, Rebecca D Folkerth, Drucilla J Roberts, Hannah C Kinney
Objective Describe the classification system for assigning the cause of stillbirth in the Safe Passage Study, an international, multi-institutional, prospective analysis conducted by the NIAAA/NICHD-funded Prenatal Alcohol in SIDS and Stillbirth (PASS) Research Network. The study mission is to determine the role of prenatal alcohol and/or cigarette smoke exposure in adverse pregnancy outcomes, including stillbirth, in a high-risk cohort of 12,000 maternal/fetal dyads. Methods The PASS Network classification system is based upon 5 "sites of origin" for cause of stillbirth, further subdivided into mechanism subcategories; both are employed to assign an ultimate cause of death...
March 2017: Pediatric and Developmental Pathology
https://www.readbyqxmd.com/read/28321338/frequency-risk-factors-and-adverse-fetomaternal-outcomes-of-placenta-previa-in-northern-tanzania
#16
Elizabeth Eliet Senkoro, Amasha H Mwanamsangu, Fransisca Seraphin Chuwa, Sia Emmanuel Msuya, Oresta Peter Mnali, Benjamin G Brown, Michael Johnson Mahande
Background and Objective. Placenta previa (PP) is a potential risk factor for obstetric hemorrhage, which is a major cause of fetomaternal morbidity and mortality in developing countries. This study aimed to determine frequency, risk factors, and adverse fetomaternal outcomes of placenta previa in Northern Tanzania. Methodology. A retrospective cohort study was conducted using maternally-linked data from Kilimanjaro Christian Medical Centre birth registry spanning 2000 to 2015. All women who gave birth to singleton infants were studied...
2017: Journal of Pregnancy
https://www.readbyqxmd.com/read/28301980/an-investigation-of-intra-individual-variability-in-children-with-fetal-alcohol-spectrum-disorder-fasd
#17
Sheliza Ali, Kimberly A Kerns, Bryce P Mulligan, Heather Carmichael Olson, Susan J Astley
Intra-individual variability (IIV) is defined as systematic within-person variation in performance either across test sessions (e.g., test/retest performance on the same task) or in one session (e.g., variations in performance on multiple trials of a single task). Higher levels of IIV have been noted as a characteristic of neurodevelopmental disorders such as attention deficit/hyperactivity disorder​ (ADHD), but IIV is yet to be investigated in fetal alcohol spectrum disorder (FASD). FASD is a term used to describe a range of conditions resulting from prenatal exposure to alcohol...
March 16, 2017: Child Neuropsychology: a Journal on Normal and Abnormal Development in Childhood and Adolescence
https://www.readbyqxmd.com/read/28294365/prevalence-of-prenatal-alcohol-exposure-in-the-state-of-texas-as-assessed-by-phosphatidylethanol-in-newborn-dried-blood-spot-specimens
#18
Ludmila N Bakhireva, Janet Sharkis, Shikhar Shrestha, Tristan J Miranda-Sohrabji, Sonnie Williams, Rajesh C Miranda
BACKGROUND: While 2-5% of school-aged children in the U.S. are estimated to be affected by Fetal Alcohol Spectrum Disorders (FASD), the prevalence of prenatal alcohol exposure (PAE) might be substantially under-reported. Our objective was to systematically estimate the prevalence of PAE in Texas by measuring a direct ethanol metabolite, phosphatidylethanol (PEth), in 1,000 infant residual dried blood spots (irDBS) in the Texas Newborn Screening Repository. METHODS: All Public Health Regions were represented proportional to their 2014 birth rate (~0...
March 13, 2017: Alcoholism, Clinical and Experimental Research
https://www.readbyqxmd.com/read/28270105/economic-evaluation-of-a-behavioral-intervention-versus-brief-advice-for-substance-use-treatment-in-pregnant-women-results-from-a-randomized-controlled-trial
#19
Xiao Xu, Kimberly A Yonkers, Jennifer Prah Ruger
BACKGROUND: Substance use in pregnancy is associated with severe maternal and fetal morbidities and substantial economic costs. However, few studies have evaluated the cost-effectiveness of substance use treatment programs in pregnant women. The purpose of this study was to evaluate the economic impact of a behavioral intervention that integrated motivational enhancement therapy with cognitive behavioral therapy (MET-CBT) for treatment of substance use in pregnancy, in comparison with brief advice...
March 7, 2017: BMC Pregnancy and Childbirth
https://www.readbyqxmd.com/read/28254158/efficacy-of-motivational-enhancement-therapy-to-decrease-alcohol-and-illicit-drug-use-in-pregnant-substance-users-reporting-baseline-alcohol-use
#20
Robin Osterman, Daniel Lewis, Theresa Winhusen
BACKGROUND: Approximately 35% of pregnant substance users in treatment report alcohol abuse, which increases the risk of fetal alcohol spectrum disorders (FASD) in their offspring. The present study was a preliminary evaluation of the efficacy of motivational enhancement therapy (MET) in decreasing alcohol use in pregnant women attending substance use treatment. METHODS: Secondary analysis of a trial evaluating the efficacy of MET, relative to treatment as usual (TAU), in improving treatment outcomes in 200 pregnant substance users...
February 18, 2017: Journal of Substance Abuse Treatment
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