keyword
MENU ▼
Read by QxMD icon Read
search

Fetal alcohol

keyword
https://www.readbyqxmd.com/read/29466290/different-risk-factors-for-very-low-birth-weight-term-small-for-gestational-age-or-preterm-birth-in-japan
#1
Naomi Tamura, Tomoyuki Hanaoka, Kumiko Ito, Atsuko Araki, Chihiro Miyashita, Sachiko Ito, Hisanori Minakami, Kazutoshi Cho, Toshiaki Endo, Kazuo Sengoku, Katsuhiko Ogasawara, Reiko Kishi
From 1985 to 2013, the mean birth weight of infants in Japan decreased from 3120 g to 3000 g, and the low-birth-weight rate among live births increased from 6.3% to 9.6%. No prospective study has elucidated the risk factors for poor fetal growth and preterm birth in recent Japanese parents, such as increased parental age, maternal body figure, assisted reproductive technology (ART), and socioeconomic status. Participants were mother-infant pairs ( n = 18,059) enrolled in a prospective birth cohort in Hokkaido, Japan from 2002 to 2013...
February 21, 2018: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/29465524/screening-and-brief-intervention-to-prevent-fetal-alcohol-spectrum-disorders
#2
(no author information available yet)
No abstract text is available yet for this article.
March 2018: Nursing
https://www.readbyqxmd.com/read/29463135/investigating-a-theatre-based-intervention-for-indigenous-youth-with-fetal-alcohol-spectrum-disorder-exploration-d-une-intervention-bas%C3%A3-e-sur-le-th%C3%A3-%C3%A3-tre-aupr%C3%A3-s-de-jeunes-autochtones-atteints-du-syndrome-d-alcoolisme-f%C3%A5-tal
#3
Michelle Keightley, Sabrina Agnihotri, Sivaniya Subramaniapillai, Julia Gray, Jennifer Keresztesi, Angela Colantonio, Helene J Polatajko, Debra Cameron, Catherine Wiseman-Hakes
BACKGROUND: Theatre-based interventions use artistic media to facilitate social and emotional awareness and have therapeutic benefits for persons with developmental disabilities and mental health problems. The role of these interventions with Indigenous youth who have emotional, behavioural, and cognitive sequelae related to fetal alcohol spectrum disorder (FASD) has not been explored. PURPOSE: The purpose of this study was to explore the experiences and acceptability of a theatre-based approach for facilitating social communication and engagement in youth with FASD...
January 1, 2018: Canadian Journal of Occupational Therapy. Revue Canadienne D'ergothérapie
https://www.readbyqxmd.com/read/29462278/neonatal-ethanol-disturbs-the-normal-maturation-of-parvalbumin-interneurons-surrounded-by-subsets-of-perineuronal-nets-in-the-cerebral-cortex-partial-reversal-by-lithium
#4
Mariko Saito, John F Smiley, Maria Hui, Kurt Masiello, Judith Betz, Maria Ilina, Mitsuo Saito, Donald A Wilson
Reduction in parvalbumin-positive (PV+) interneurons is observed in adult mice exposed to ethanol at postnatal day 7 (P7), a late gestation fetal alcohol spectrum disorder model. To evaluate whether PV+ cells are lost, or PV expression is reduced, we quantified PV+ and associated perineuronal net (PNN)+ cell densities in barrel cortex. While PNN+ cell density was not reduced by P7 ethanol, PV cell density decreased by 25% at P90 with no decrease at P14. PNN+ cells in controls were virtually all PV+, whereas more than 20% lacked PV in ethanol-treated adult animals...
February 16, 2018: Cerebral Cortex
https://www.readbyqxmd.com/read/29456493/administration-of-ketamine-causes-autophagy-and-apoptosis-in-the-rat-fetal-hippocampus-and-in-pc12-cells
#5
Xinran Li, Yanan Li, Jinghua Zhao, Lina Li, Yuxin Wang, Yiming Zhang, Yue Li, Yu Chen, Wenhan Liu, Li Gao
Drug abuse during pregnancy is a serious problem. Like alcohol, anticonvulsants, sedatives, and anesthetics, such as ketamine, can pass through the placental barrier and affect the growing fetus. However, the mechanism by which ketamine causes damage to fetal rats is not well understood. Therefore, in this study, we anesthetized pregnant rats with ketamine and evaluated the Total Antioxidant Capacity (T-AOC), Reactive Oxygen Species (ROS), and Malondialdehyde (MDA). Moreover, we determined changes in the levels of Cleaved-Caspase-3 (C-Caspase-3), Beclin-1, B-cell lymphoma-2 (Bcl-2), Bcl-2 Associated X Protein (Bax), Autophagy-related gene 4 (Atg4), Atg5, p62 (SQSTM1), and marker of autophagy Light Chain 3 (LC3)...
2018: Frontiers in Cellular Neuroscience
https://www.readbyqxmd.com/read/29453023/implications-of-altered-maternal-cytokine-concentrations-on-infant-outcomes-in-children-with-prenatal-alcohol-exposure
#6
K D Sowell, J Y Uriu-Adams, J Van de Water, C D Chambers, C D Coles, J A Kable, L Yevtushok, N Zymak-Zakutnya, W Wertelecki, C L Keen
Excessive alcohol consumption has been shown to increase serum plasma levels of numerous immune cytokines. Maternal immune activation and elevated cytokines have been implicated in certain neurological disorders (e.g., autism and schizophrenia) in the offspring. We investigated the hypothesis that elevated cytokines during pregnancy are a risk factor in women who gave birth to a child with Fetal Alcohol Spectrum Disorder (FASD) or a child with neurobehavioral impairment, regardless of prenatal alcohol exposure...
August 12, 2017: Alcohol
https://www.readbyqxmd.com/read/29440216/fetal-alcohol-spectrum-disorder-and-youth-justice-a-prevalence-study-among-young-people-sentenced-to-detention-in-western-australia
#7
Carol Bower, Rochelle E Watkins, Raewyn C Mutch, Rhonda Marriott, Jacinta Freeman, Natalie R Kippin, Bernadette Safe, Carmela Pestell, Candy S C Cheung, Helen Shield, Lodewicka Tarratt, Alex Springall, Jasmine Taylor, Noni Walker, Emma Argiro, Suze Leitão, Sharynne Hamilton, Carmen Condon, Hayley M Passmore, Roslyn Giglia
OBJECTIVES: To estimate the prevalence of fetal alcohol spectrum disorder (FASD) among young people in youth detention in Australia. Neurodevelopmental impairments due to FASD can predispose young people to engagement with the law. Canadian studies identified FASD in 11%-23% of young people in corrective services, but there are no data for Australia. DESIGN: Multidisciplinary assessment of all young people aged 10-17 years 11 months and sentenced to detention in the only youth detention centre in Western Australia, from May 2015 to December 2016...
February 13, 2018: BMJ Open
https://www.readbyqxmd.com/read/29438595/effects-of-early-alcohol-exposure-on-functional-organization-and-microstructure-of-a-visual-tactile-integrative-circuit
#8
Shiyu Tang, Su Xu, Rao P Gullapalli, Alexandre E Medina
BACKGROUND: Children with fetal alcohol spectrum disorders (FASD) often have deficits associated with multisensory processing. Because ethanol disrupts activity-dependent neuronal plasticity, a process that is essential for refining connections during cortical development, we hypothesize that early alcohol exposure results in alterations in multisensory cortical networks, which could explain the multisensory processing deficits seen in FASD. Here, we use a gyrencephalic animal model to test the prediction that early alcohol exposure alters the functional connectivity and microstructural features of the rostral posterior parietal cortex (PPr), a visual-tactile integrative area...
February 13, 2018: Alcoholism, Clinical and Experimental Research
https://www.readbyqxmd.com/read/29432645/alcohol-binge-drinking-in-early-pregnancy-and-the-effect-on-fetal-growth-a-cohort-study
#9
Julie Anna Slavensky, Ulrik Schiøler Kesmodel
INTRODUCTION: Alcohol binge drinking is common in early pregnancy and is a well-established risk factor for subsequent child health. Yet very few studies have investigated the effect on fetal growth. Furthermore it has also been speculated whether the timing of binge drinking is a determining factor for neonatal growth. The objective of this study was to assess the potential effect of binge drinking and different drinking patterns (timing and number of binge drinking episodes) in early pregnancy on fetal growth estimated by birthweight and birth length...
February 12, 2018: Acta Obstetricia et Gynecologica Scandinavica
https://www.readbyqxmd.com/read/29432031/deferred-diagnosis-in-children-assessed-for-fetal-alcohol-spectrum-disorder
#10
Katherine Flannigan, Kamaldeep Gill, Jacqueline Pei, Gail Andrew, Hasu Rajani, Audrey McFarlane, Teresa O'Riordan, Brent Symes, Carmen Rasmussen
Early intervention for individuals with FASD is paramount, thus exploring factors that affect the diagnostic process is critical. This process can be complicated by challenges gathering background information, accurately evaluating higher-level cognitive skills across ages, and teasing apart the impact of life adversities from the effects of prenatal alcohol exposure. This study is a retrospective file review of 154 children (44% female; mean age 8.4 years, range 1.0 to 16.9) deferred at their first FASD assessment, and 51 (43% female; mean 9...
February 12, 2018: Applied Neuropsychology. Child
https://www.readbyqxmd.com/read/29411031/prevalence-of-fetal-alcohol-spectrum-disorders-in-4-us-communities
#11
Philip A May, Christina D Chambers, Wendy O Kalberg, Jennifer Zellner, Haruna Feldman, David Buckley, David Kopald, Julie M Hasken, Ronghui Xu, Gordon Honerkamp-Smith, Howard Taras, Melanie A Manning, Luther K Robinson, Margaret P Adam, Omar Abdul-Rahman, Keith Vaux, Tamison Jewett, Amy J Elliott, Julie A Kable, Natacha Akshoomoff, Daniel Falk, Judith A Arroyo, Dale Hereld, Edward P Riley, Michael E Charness, Claire D Coles, Kenneth R Warren, Kenneth Lyons Jones, H Eugene Hoyme
Importance: Fetal alcohol spectrum disorders are costly, life-long disabilities. Older data suggested the prevalence of the disorder in the United States was 10 per 1000 children; however, there are few current estimates based on larger, diverse US population samples. Objective: To estimate the prevalence of fetal alcohol spectrum disorders, including fetal alcohol syndrome, partial fetal alcohol syndrome, and alcohol-related neurodevelopmental disorder, in 4 regions of the United States...
February 6, 2018: JAMA: the Journal of the American Medical Association
https://www.readbyqxmd.com/read/29411016/implications-of-higher-than-expected-prevalence-of-fetal-alcohol-spectrum-disorders
#12
EDITORIAL
Shannon Lange, Jürgen Rehm, Svetlana Popova
No abstract text is available yet for this article.
February 6, 2018: JAMA: the Journal of the American Medical Association
https://www.readbyqxmd.com/read/29408587/fetal-regional-brain-protein-signature-in-fasd-rat-model
#13
Katie L Davis-Anderson, Hendrik Wesseling, Lara M Siebert, Emilie R Lunde-Young, Vishal D Naik, Hanno Steen, Jayanth Ramadoss
Fetal alcohol spectrum disorders (FASD) describe neurodevelopmental deficits in children exposed to alcohol in utero. We hypothesized that gestational alcohol significantly alters fetal brain regional protein signature. Pregnant rats were binge-treated with alcohol or pair-fed and nutritionally-controlled. Mass spectrometry identified 1,806, 2,077, and 1,456 quantifiable proteins in the fetal hippocampus, cortex, and cerebellum, respectively. A stronger effect of alcohol exposure on the hippocampal proteome was noted: over 600 hippocampal proteins were significantly (P < 0...
January 31, 2018: Reproductive Toxicology
https://www.readbyqxmd.com/read/29398060/utility-of-genetic-testing-in-fetal-alcohol-spectrum-disorder
#14
Saumya S Jamuar, Jonathan D Picker, Joan M Stoler
OBJECTIVE: To study the utility of genetic evaluation and testing in patients with suspected fetal alcohol spectrum disorder (FASD). STUDY DESIGN: We performed a retrospective chart review of all patients (n = 36) referred for evaluation for suspected FASD to the genetics clinic at Boston Children's Hospital between January 2006 and January 2013. Records of all patients were reviewed to obtain the medical history, family history, examination findings, and investigations, including genetic testing...
February 2, 2018: Journal of Pediatrics
https://www.readbyqxmd.com/read/29391132/neonatal-ethanol-and-choline-treatments-alter-the-morphology-of-developing-rat-hippocampal-pyramidal-neurons-in-opposite-directions
#15
C M Goeke, M L Roberts, J G Hashimoto, D A Finn, M Guizzetti
Some of the neurobehavioral deficits identified in children with Fetal Alcohol Spectrum Disorders (FASDs) have been recapitulated in a binge model of gestational third trimester-equivalent ethanol (EtOH) exposure, in which Sprague-Dawley rats are intragastrically intubated between post-natal day (PD) 4 and PD9 with high doses of EtOH. In this model, the ameliorating effects of choline (Chol) administration on hippocampus-dependent behaviors altered by EtOH have also been extensively documented. In the present study, we investigated the effects of EtOH (5 g/kg/day) and/or Chol (100 mg/kg/day) on morphometric parameters of CA1 pyramidal neurons by Golgi-Cox staining followed by Neurolucida tracing and analysis...
January 29, 2018: Neuroscience
https://www.readbyqxmd.com/read/29384835/screening-and-brief-intervention-to-prevent-fetal-alcohol-spectrum-disorders
#16
Irene Kane, Ann M Mitchell, Deborah Finnell, Holly Hagle, Kathy Puskar, Brayden Kameg, Emily Knapp
No abstract text is available yet for this article.
January 30, 2018: Nursing
https://www.readbyqxmd.com/read/29370712/effect-of-preeclampsia-on-human-milk-cytokine-levels
#17
Natália Alves de Freitas, Luiza Tavares Carneiro Santiago, Cilmery Suemi Kurokawa, José Donizeti de Meira Junior, José Eduardo Corrente, Ligia Maria Suppo de Souza Rugolo
INTRODUCTION: Preeclampsia (PE) is a systemic inflammatory disease, and its effect on human milk immune components is poorly understood. OBJECTIVE: To investigate whether PE affects human milk cytokine levels. METHODS: This was a prospective observational study involving mothers diagnosed with PE and with singleton pregnancy with no fetal malformation. The following cases were excluded: diabetes, chorioamnionitis, use of illicit drugs and alcohol, mastitis and congenital infection...
January 25, 2018: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/29370546/an-environmental-scan-of-the-role-of-nurses-in-preventing-fetal-alcohol-spectrum-disorders
#18
Ann M Mitchell, Diane K King, Brayden Kameg, Holly Hagle, Dawn Lindsay, Bridget L Hanson, Irene Kane, Kathy Puskar, Susan Albrecht, Carolyn Shaputnic, Becky R Porter, Alexandra E Edwards, Emily Knapp
Nurses are in an ideal position to talk to their patients of reproductive age about alcohol use and encourage the prevention of alcohol-exposed pregnancies. Effective conversations can be efficiently included in the clinical encounter to identify alcohol misuse and offer appropriate follow-up. This report presents results of an environmental scan of resources relevant to nursing professionals and nurses' role in addressing alcohol misuse. Gaps in nursing education and practice guidelines with regard to defining the nursing role in preventing alcohol-exposed pregnancies were revealed...
January 25, 2018: Issues in Mental Health Nursing
https://www.readbyqxmd.com/read/29370535/effects-of-prenatal-alcohol-exposure-pae-insights-into-fasd-using-pae-mouse-models
#19
Berardino Petrelli, Joanne Weinberg, Geoffrey G Hicks
The potential impact of prenatal alcohol exposure (PAE) varies considerably among exposed individuals, with some displaying serious alcohol-related effects and others showing few or even no overt signs of a fetal alcohol spectrum disorder (FASD). In animal models variables such as nutrition, genetic background, health, other drugs, and stress, as well as dosage, duration and gestational timing of alcohol exposure can all be controlled in a way not possible in a clinical situation. In this review we examine mouse PAE models and focus on those with demonstrated craniofacial malformations, abnormal brain development, or behavioural phenotypes that may be considered FASD-like outcomes...
January 25, 2018: Biochemistry and Cell Biology, Biochimie et Biologie Cellulaire
https://www.readbyqxmd.com/read/29368410/recognition-of-clinical-characteristics-for-population-based-surveillance-of-fetal-alcohol-syndrome
#20
Jennifer G Andrews, Maureen K Galindo, F John Meaney, Argelia Benavides, Linnette Mayate, Deborah Fox, Sydney Pettygrove, Leslie O'Leary, Christopher Cunniff
BACKGROUND: The diagnosis of fetal alcohol syndrome (FAS) rests on identification of characteristic facial, growth, and central nervous system (CNS) features. Public health surveillance of FAS depends on documentation of these characteristics. We evaluated if reporting of FAS characteristics is associated with the type of provider examining the child. METHODS: We analyzed cases aged 7-9 years from the Fetal Alcohol Syndrome Surveillance Network II (FASSNetII). We included cases whose surveillance records included the type of provider (qualifying provider: developmental pediatrician, geneticist, neonatologist; other physician; or other provider) who evaluated the child as well as the FAS diagnostic characteristics (facial dysmorphology, CNS impairment, and/or growth deficiency) reported by the provider...
January 25, 2018: Birth defects research
keyword
keyword
4986
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"