keyword
MENU ▼
Read by QxMD icon Read
search

high protein diet

keyword
https://www.readbyqxmd.com/read/28213860/epidemiology-of-stone-disease-across-the-world
#1
Igor Sorokin, Charalampos Mamoulakis, Katsuhito Miyazawa, Allen Rodgers, Jamsheer Talati, Yair Lotan
Nephrolithiasis is a highly prevalent disease worldwide with rates ranging from 7 to 13% in North America, 5-9% in Europe, and 1-5% in Asia. Due to high rates of new and recurrent stones, management of stones is expensive and the disease has a high level of acute and chronic morbidity. The goal of this study is to review the epidemiology of stone disease in order to improve patient care. A review of the literature was conducted through a search on Pubmed(®), Medline(®), and Google Scholar(®). This review was presented and peer-reviewed at the 3rd International Consultation on Stone Disease during the 2014 Société Internationale d'Urologie Congress in Glasgow...
February 17, 2017: World Journal of Urology
https://www.readbyqxmd.com/read/28213613/an-atf4-atg5-signaling-in-hypothalamic-pomc-neurons-regulates-fat-mass-via-affecting-energy-expenditure
#2
Yuzhong Xiao, Yalan Deng, Feixiang Yuan, Tingting Xia, Hao Liu, Zhigang Li, Zhixue Liu, Hao Ying, Yi Liu, Qiwei Zhai, Shanghai Chen, Feifan Guo
Although many biological functions of activating transcription factor 4 (ATF4) have been identified, a role of hypothalamic ATF4 in the regulation of energy homeostasis is poorly understood. Here, we showed that hypothalamic pro-opiomelanocortin (POMC) neurons specific ATF4 knockout (PAKO) mice are lean and have higher energy expenditure. Furthermore, PAKO mice were resistant to high-fat diet (HFD)-induced obesity, glucose intolerance and leptin resistance. Moreover, the expression of autophagy protein 5 (ATG5) was increased or decreased by ATF4 knockdown or over-expression, respectively, and ATF4 inhibited the transcription of ATG5 by binding to the basic zipper-containing protein (bZIP) sites on its promoter...
February 17, 2017: Diabetes
https://www.readbyqxmd.com/read/28213520/cholesterol-up-regulates-neuronal-g-protein-gated-inwardly-rectifying-potassium-girk-channel-activity-in-the-hippocampus
#3
Anna N Bukiya, Serdar Durdagi, Sergei Noskov, Avia Rosenhouse-Dantsker
Hypercholesterolemia is a well-known risk factor for the development of neurodegenerative disease. However, the underlying mechanisms are mostly unknown. In recent years, it has become increasingly evident that cholesterol-driven effects on physiology and pathophysiology derive from its ability to alter the function of a variety of membrane proteins including ion channels. Yet, the effect of cholesterol on G protein-gated inwardly rectifying potassium (GIRK) channels expressed in the brain is unknown. GIRK channels mediate the actions of inhibitory brain neurotransmitters...
February 17, 2017: Journal of Biological Chemistry
https://www.readbyqxmd.com/read/28213321/effects-of-selenium-lead-interaction-on-the-gene-expression-of-inflammatory-factors-and-selenoproteins-in-chicken-neutrophils
#4
Xiaojing Li, Mengyuan Xing, Menghao Chen, Jinxin Zhao, Ruifeng Fan, Xia Zhao, Changyu Cao, Jie Yang, Ziwei Zhang, Shiwen Xu
Lead (Pb) is one of the most highly toxic metal pollutant that can cause damage to the immune system. It is known that selenium (Se) can antagonize heavy metals. To explore the toxic effects of Pb poisoning on bird immune cells, as well as the alleviating effects of Se on Pb, Se supplement and/or Pb poisoning chicken models were established. One hundred and eighty Hyline 7-day-old male chickens received either Se (1mg Se per kg of diet), Pb (350mg Pb per liter water) or Se+Pb in their diet and water for 90 days...
February 14, 2017: Ecotoxicology and Environmental Safety
https://www.readbyqxmd.com/read/28213287/butein-induction-of-ho-1-by-p38-mapk-nrf2-pathway-in-adipocytes-attenuates-high-fat-diet-induced-adipose-hypertrophy-in-mice
#5
Zheng Wang, Sun-O Ka, Youngyi Lee, Byung-Hyun Park, Eun Ju Bae
Adipose tissue inflammation and oxidative stress are key components in the development of obesity and insulin resistance. Heme oxygenase (HO)-1 in adipocytes protects against obesity and adipose dysfunction. In this study, we report the identification of butein, a flavonoid chalcone, as a novel inducer of HO-1 expression in adipocytes in vitro and in vivo. Butein upregulated HO-1 mRNA and protein expression in 3T3-L1 adipocytes, accompanied by Kelch-Like ECH-Associated Protein (Keap) 1 degradation and increase in the nuclear level of nuclear factor erythroid 2-related factor 2 (Nrf2)...
February 14, 2017: European Journal of Pharmacology
https://www.readbyqxmd.com/read/28213107/hypoglycemic-effect-of-the-polyphenols-rich-extract-from-rose-rugosa-thunb-on-high-fat-diet-and-stz-induced-diabetic-rats
#6
Liu Liu, Dan Tang, Haiqing Zhao, Xuelei Xin, Haji Akber Aisa
ETHNOPHARMACOLOGICAL RELEVANCE: Rosa rugosa Thunb is traditional Uygur medicine, it is widely used for regulating blood condition, nourishing liver and gallbladder in Uygur ancient prescription. But the mechanism of Rosa rugosa Thunb on diabetes is still unclear. In here, we studied the hypoglycemic effect and explained one probable pathway of polyphenols rich extract from Rosa rugosa Thunb (RPE) on diabetic rats. MATERIALS AND METHODS: In vitro, the effect of RPE on α-glucosidase inhibition was finished, and the antioxidant activity of RPE was evaluated by ABTS and DPPH assay...
February 14, 2017: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/28212704/neurochemical-differences-in-learning-and-memory-paradigms-among-rats-supplemented-with-anthocyanin-rich-blueberry-diets-and-exposed-to-acute-doses-of-56-fe-particles
#7
Shibu M Poulose, Bernard M Rabin, Donna F Bielinski, Megan E Kelly, Marshall G Miller, Nopporn Thanthaeng, Barbara Shukitt-Hale
The protective effects of anthocyanin-rich blueberries (BB) on brain health are well documented and are particularly important under conditions of high oxidative stress, which can lead to "accelerated aging." One such scenario is exposure to space radiation, consisting of high-energy and -charge particles (HZE), which are known to cause cognitive dysfunction and deleterious neurochemical alterations. We recently tested the behavioral and neurochemical effects of acute exposure to HZE particles such as (56)Fe, within 24-48h after exposure, and found that radiation primarily affects memory and not learning...
February 2017: Life Sciences in Space Research
https://www.readbyqxmd.com/read/28212448/hepatic-transcriptome-analysis-and-identification-of-differentially-expressed-genes-response-to-dietary-oxidized-fish-oil-in-loach-misgurnus-anguillicaudatus
#8
Yin Zhang, Yang Li, Xiao Liang, Xiaojuan Cao, Longfei Huang, Jie Yan, Yanxing Wei, Jian Gao
RNA sequencing and short-read assembly were utilized to produce a transcriptome of livers from loaches (Misgurnus anguillicaudatus) fed with three different diets respectively containing fresh fish oil (FO group), medium oxidized fish oil (MO group) and high oxidized fish oil (HO group). A total of 60,663 unigenes were obtained in this study, with mean length 848.74 bp. 50,814, 49,584 and 49,814 unigenes were respectively obtained from FO, MO and HO groups. There were 2,343 differentially expressed genes between FO and MO, with 855 down- and 1,488 up-regulated genes in the MO group...
2017: PloS One
https://www.readbyqxmd.com/read/28212343/oxyresveratrol-supplementation-to-c57bl-6-mice-fed-with-a-high-fat-diet-ameliorates-obesity-associated-symptoms
#9
Hui Yuan Tan, Iris Mei Ying Tse, Edmund Tsze Shing Li, Mingfu Wang
Oxyresveratrol has been proven effective in inhibiting adipogenesis in a 3T3-L1 cell model. We investigated the preventive effect of oxyresveratrol supplementation on obesity development in high-fat diet-fed mice. Male C57bl/6 mice were randomly subjected to control (5% fat by weight, LF), high-fat (30% fat by weight, HF), and high-fat supplemented with 0.25% and 0.5% oxyresveratrol (OXY1 and OXY2, respectively) diet groups for eight weeks. Oxyresveratrol supplementation effectively alleviated obesity-associated symptoms such as insulin resistance, hyperglycemia, and hepatic steatosis in high-fat diet-fed mice...
February 16, 2017: Nutrients
https://www.readbyqxmd.com/read/28211103/impaired-learning-and-memory-in-rats-induced-by-a-high-fat-diet-involvement-with-the-imbalance-of-nesfatin-1-abundance-and-copine-6-expression
#10
Zheng Chen, Ya-Yun Xu, Rui Wu, Yin-Xiu Han, Yue Yu, Jin-Fang Ge, Fei-Hu Chen
Non-alcoholic fatty liver disease (NAFLD) is the most common cause of chronic liver disease, resulting not only in liver dysfunction, glucose and lipid metabolism disorder, but also in neuropsychiatric damage. In the present study, a NAFLD rat model was established via feeding of a high-fat diet, and the behavior was observed via the open field test (OFT), the sucrose preference test (SPT), the elevated plus maze (EPM), the forced swimming test (FST), and the Morris water maze (MWM). The plasma concentrations of alanine aminotransferase (ALT), glucose, free fatty acid (FFA), total cholesterol (TC), triglyceride (TG), high-density lipoprotein cholesterol (HDL-C), and low-density lipoprotein cholesterol (LDL-C) were detected using chemiluminescence technique...
February 17, 2017: Journal of Neuroendocrinology
https://www.readbyqxmd.com/read/28209760/glucoraphanin-ameliorates-obesity-and-insulin-resistance-through-adipose-tissue-browning-and-reduction-of-metabolic-endotoxemia-in-mice
#11
Naoto Nagata, Liang Xu, Susumu Kohno, Yusuke Ushida, Yudai Aoki, Ryohei Umeda, Nobuo Fuke, Fen Zhuge, Yinhua Ni, Mayumi Nagashimada, Chiaki Takahashi, Hiroyuki Suganuma, Shuichi Kaneko, Tsuguhito Ota
Low-grade sustained inflammation links obesity to insulin resistance and nonalcoholic fatty liver disease (NAFLD). However, therapeutic approaches to improve systemic energy balance and chronic inflammation in obesity are limited. Pharmacological activation of nuclear factor (erythroid-derived 2)-like 2 (Nrf2) alleviates obesity and insulin resistance in mice; however, Nrf2 inducers are not clinically available owing to safety concerns. Thus, we examined whether dietary glucoraphanin, a stable precursor of the Nrf2 inducer sulforaphane, ameliorates systemic energy balance, chronic inflammation, insulin resistance, and NAFLD in high-fat diet (HFD)-fed mice...
February 16, 2017: Diabetes
https://www.readbyqxmd.com/read/28209562/vinexin-%C3%AE-ablation-inhibits-atherosclerosis-in-apolipoprotein-e-deficient-mice-by-inactivating-the-akt-nuclear-factor-%C3%AE%C2%BAb-inflammatory-axis
#12
Hongjing Guan, Wen-Lin Cheng, Junhong Guo, Meng-Lin Chao, Yan Zhang, Jun Gong, Xue-Yong Zhu, Zhi-Gang She, Zan Huang, Hongliang Li
BACKGROUND: Vinexin β is a novel adaptor protein that regulates cellular adhesion, cytoskeletal reorganization, signal transduction, and transcription; however, the exact role that vinexin β plays in atherosclerosis remains unknown. METHODS AND RESULTS: Immunoblot analysis showed that vinexin β expression is upregulated in the atherosclerotic lesions of both patients with coronary heart disease and hyperlipemic apolipoprotein E-deficient mice and is primarily localized in macrophages indicated by immunofluorescence staining...
February 16, 2017: Journal of the American Heart Association
https://www.readbyqxmd.com/read/28208647/soy-leaf-extract-exerts-atheroprotective-effects-via-modulation-of-kr%C3%A3-ppel-like-factor-2-and-adhesion-molecules
#13
Jong-Min Han, Hua Li, Moon-Hee Cho, Seung-Hwa Baek, Chul-Ho Lee, Ho-Yong Park, Tae-Sook Jeong
Soy-leaf extracts exert their cardioprotective effects by inducing endothelium-dependent vasodilation in the arteries, and they favorably modulate the serum lipid profile. In this study, we investigated the atheroprotective effects of an ethanol extract of soy leaf (ESL) in human umbilical vein endothelial cells (HUVECs) and high-cholesterol diet (HCD)-fed low-density lipoprotein receptor deficient (LDLR-/-) mice. ESL induced the expression of Krüppel-like factor 2 (KLF2), an endothelial transcription factor, and endothelial nitric oxide synthase (eNOS), and suppressed the expression of vascular cell adhesion molecule-1 (VCAM-1) and intercellular adhesion molecule-1 (ICAM-1) through moderate inflammatory signal activation, not only in tumor necrosis factor-α (TNF-α)-stimulated HUVECs but also in 7-ketocholesterol (7-KC)-stimulated HUVECs...
February 10, 2017: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/28207502/impact-of-the-dietary-fatty-acid-intake-on-c-reactive-protein-levels-in-us-adults
#14
Mohsen Mazidi, Hong-Kai Gao, Hassan Vatanparast, Andre Pascal Kengne
Growing evidence suggests that the effects of diet on cardiovascular disease (CVD) occur through mechanisms involving subclinical inflammation. We assessed whether reported dietary fatty acid intake correlates with a serum high-sensitivity C-reactive protein (hs-CRP) concentration in a population-based sample of US men and women.In this cross-sectional analysis, participants were selected from the US National Health and Nutrition Examination Survey (NHANES) and restricted to those with available data on dietary intake, biochemical and anthropometric measurements from 2001 to 2010...
February 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28205325/wholegrain-oat-diet-changes-the-expression-of-genes-associated-with-intestinal-bile-acid-transport
#15
Kristina E Andersson, Aakash Chawade, Narda Thuresson, Ana Rascon, Rickard Öste, Olov Sterner, Olof Olsson, Per Hellstrand
SCOPE: The molecular mechanisms underlying the cholesterol-lowering properties of oats are only partly known. To study possible pathways involved, we investigated gene expressions in the liver and small intestine of mice fed oats. METHOD AND RESULTS: Cholesterol and bile acids were analysed in plasma and faeces from LDL-receptor deficient (LDLr(-/-) ) mice fed Western diet with wholegrain oats. A transcriptome analysis of mRNA from liver and jejunum was performed together with quantitative RT-PCR...
February 16, 2017: Molecular Nutrition & Food Research
https://www.readbyqxmd.com/read/28203647/the-potential-of-blue-lupins-as-a-protein-source-in-the-diets-of-laying-hens
#16
Michael R F Lee, Sarah Parkinson, Hannah R Fleming, Vince J Theobald, Dave K Leemans, Tony Burgess
Layers diets typically contain 15-20% soya due to its high crude protein content (ca. 36%). Reliance on soya for protein can result in large increases in cost of feed due to the law of supply and demand as a global commodity. Lupin grains have high protein content (35-40%) but previous experience with white lupins has shown toxic effects in poultry due to high levels alkaloids and poor performance due to anti-nutritional Non-starch polysaccharides (NSP). Here blue lupins either processed or whole were trialled for their potential as a protein source...
December 2016: Veterinary and Animal Science
https://www.readbyqxmd.com/read/28202779/fasting-mimicking-diet-and-markers-risk-factors-for-aging-diabetes-cancer-and-cardiovascular-disease
#17
Min Wei, Sebastian Brandhorst, Mahshid Shelehchi, Hamed Mirzaei, Chia Wei Cheng, Julia Budniak, Susan Groshen, Wendy J Mack, Esra Guen, Stefano Di Biase, Pinchas Cohen, Todd E Morgan, Tanya Dorff, Kurt Hong, Andreas Michalsen, Alessandro Laviano, Valter D Longo
Calorie restriction or changes in dietary composition can enhance healthy aging, but the inability of most subjects to adhere to chronic and extreme diets, as well as potentially adverse effects, limits their application. We randomized 100 generally healthy participants from the United States into two study arms and tested the effects of a fasting-mimicking diet (FMD)-low in calories, sugars, and protein but high in unsaturated fats-on markers/risk factors associated with aging and age-related diseases. We compared subjects who followed 3 months of an unrestricted diet to subjects who consumed the FMD for 5 consecutive days per month for 3 months...
February 15, 2017: Science Translational Medicine
https://www.readbyqxmd.com/read/28202685/high-protein-paternal-diet-confers-an-advantage-to-sons-in-sperm-competition
#18
Felix Zajitschek, Susanne Zajitschek, Mollie Manier
Parental environment can widely influence offspring phenotype, but paternal effects in the absence of parental care remain poorly understood. We asked if protein content in the larval diet of fathers affected paternity success and gene expression in their sons. We found that males reared on high-protein diet had sons that fared better during sperm competition, suggesting that postcopulatory sexual selection is subject to transgenerational paternal effects. Moreover, immune response genes were downregulated in sons of low-protein fathers, while genes involved in metabolic and reproductive processes were upregulated...
February 2017: Biology Letters
https://www.readbyqxmd.com/read/28202548/neutrophil-elastase-regulates-emergency-myelopoiesis-preceding-systemic-inflammation-in-diet-induced-obesity
#19
Jun-Yuan Huang, Qiong Lin Zhou, Chun-Hong Huang, Ye Song, Andria G Sharma, Zhangping Liao, Kavin Zhu, Miles W Massidda, Ryan R Jamieson, Jun-Yuan Zhang, Daniel G Tenen, Zhen Y Jiang
Inflammation plays a significant role in the development of obesity-related complications, but the molecular events that initiate and propagate such inflammation remain unclear. Here, we report that mice fed a high-fat diet (HFD) for as short as one to three days show increased myeloid progenitors differentiation into neutrophils and monocytes but reduced B lymphocyte production in the bone marrow (BM). Levels of neutrophil elastase (NE) and the nuclear factors CCAAT-enhancer-binding protein alpha (C/EBPα) and growth factor independent 1 (GFI-1) are elevated in hematopoietic stem and progenitor cells (HSPCs) from HFD-fed mice, but mice lacking either NE or C/EBPα are resistant to HFD-induced myelopoiesis...
February 15, 2017: Journal of Biological Chemistry
https://www.readbyqxmd.com/read/28202438/effect-of-food-deprivation-or-short-term-western-diet-feeding-on-bdnf-protein-expression-in-the-hypothalamic-arcuate-paraventricular-and-ventromedial-nuclei
#20
Kaitlyn Elizabeth Gilland, Edward A Fox
Mutations in the brain-derived neurotrophic factor (BDNF) gene are associated with human obesity and BDNF has potent inhibitory effects on eating and body weight. Little is known about the effects of energy-balance manipulations on BDNF protein in the hypothalamus, though this brain region is critical for regulation of feeding and body weight and has high levels of BDNF. Here we investigated the effects of negative and positive energy status on BDNF protein levels in the arcuate (ARC), paraventricular (PVN), and ventromedial (VMH) hypothalamic nuclei, and the ectorhinal cortex...
February 15, 2017: American Journal of Physiology. Regulatory, Integrative and Comparative Physiology
keyword
keyword
49841
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"