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https://www.readbyqxmd.com/read/29031077/4-quinolone-hybrids-and-their-antibacterial-activities
#1
Yuan-Qiang Hu, Shu Zhang, Zhi Xu, Zao-Sheng Lv, Ming-Liang Liu, Lian-Shun Feng
The emergence and wide-spread of drug-resistant bacteria including multi-drug resistant and pan-drug resistant pathogens which are associated with considerable mortality, represent a significant global health threat. 4-Quinolones which are exemplified by fluoroquinolones are the second largest chemotherapy agents used in clinical practice for the treatment of various bacterial infections. However, the resistance of bacteria to 4-quinolones develops rapidly and spreads widely throughout the world due to the long-term, inappropriate use and even abuse...
September 28, 2017: European Journal of Medicinal Chemistry
https://www.readbyqxmd.com/read/29029215/child-sexual-abuse-and-depression-in-late-life-for-men-a-population-based-longitudinal-analysis
#2
Scott D Easton, Jooyoung Kong, Matt C Gregas, Ce Shen, Kevin Shafer
Objective: Research investigating long-term effects of childhood sexual abuse (CSA) on mental health for men is vastly underdeveloped. This study strengthened the knowledge base by examining: (a) long-term trajectories of depressive symptoms for men with and without a history of CSA, and (b) moderating effects of social support over time. Method: We analyzed multiple waves of data from the Wisconsin Longitudinal Study. The sample (N = 2,451) consisted of men with histories of CSA and a stratified, randomly sampled comparison group...
September 27, 2017: Journals of Gerontology. Series B, Psychological Sciences and Social Sciences
https://www.readbyqxmd.com/read/29027200/do-personality-traits-mediate-the-relationship-between-childhood-abuse-and-migraine-an-exploration-of-the-relationships-in-young-adults-using-the-add-health-dataset
#3
Monita Karmakar, Jon D Elhai, Aliaksandr A Amialchuk, Gretchen E Tietjen
BACKGROUND: Personality traits (especially neuroticism) and childhood maltreatment have been independently related to many negative health outcomes later in life, including migraine. Studies have also shown the association between childhood maltreatment and maladaptive personality traits. The mediating role of personality traits on the relationship between childhood maltreatment and depression, psychological distress, and alcohol dependence has been extensively studied. However, this type of mediation has not been studied in the case of the development of migraine...
October 13, 2017: Headache
https://www.readbyqxmd.com/read/29027058/the-impact-of-religiosity-on-substance-abuse-and-obesity-in-african-americans
#4
Bernice A Dodor, Michael A Robinson, Reed Watson, David Meetz, Ronald Wicker
Among the African American community, there exist many health disparities which warrant greater examination through the practice of social work. The aim of the present research was to explore the impact of religiosity on substance abuse and obesity among African American populations by employing a systematic review of the current body of literature on this subject. While many of the studies reviewed found at least a weak relationship between religiosity and obesity, such results were not consistent across all materials examined...
October 12, 2017: Journal of Religion and Health
https://www.readbyqxmd.com/read/29027042/-sex-in-a-relationship-versus-sex-during-a-one-night-stand-the-link-between-mental-representations-of-consensual-sexuality-mating-strategies-and-sexual-experience-in-heterosexual-women-and-men
#5
Steffen Landgraf, Isabella von Treskow, Michael Osterheider
Sexual scripts, that is, the mental representations of sexual behavior, are highly influenced by mating strategies and sexual experience. The relationship between these factors and sexual scripts is, however, poorly understood. Therefore, we assessed how long-term (e.g., "sex in a relationship") and short-term (e.g., "one-night stand") strategies, as well as experience with highly scripted sexual practices (BDSM: bondage-discipline, dominance-submission, sadism-masochism), influence verbalized sexual script composition and detailedness...
October 12, 2017: Archives of Sexual Behavior
https://www.readbyqxmd.com/read/29027039/patterns-of-alcohol-abuse-depression-and-intimate-partner-violence-among-township-mothers-in-south-africa-over-5-years
#6
Emily C Davis, Mary Jane Rotheram-Borus, Thomas W Weichle, Roxana Rezai, Mark Tomlinson
Alcohol is a major contributor to the global burden of disease. In South Africa, alcohol abuse is hypothesized to correlate with women's HIV status, mental health, and partner relationships over time. All pregnant women in 12 urban, low-income, Cape Town neighborhoods were interviewed at baseline, post-birth, and at 6, 12, 36, and 60 months following delivery with retention rates from 82.5 to 94%. Women were assessed for any alcohol use, problematic drinking, depression, intimate partner violence, and HIV status...
October 12, 2017: AIDS and Behavior
https://www.readbyqxmd.com/read/29026488/a-longitudinal-study-on-the-effects-of-negative-rearing-experiences-on-adolescents-social-withdrawal-and-aggression
#7
Kyung-Suk Lee, Ok-Joo Choi, Joon-Ho Kim
BACKGROUND: Children who have experienced negative rearing behaviors show a lack of self-confidence due to emotional instability and are reserved in interpersonal relationships. This can lead to failure in social adaptation and a high risk of depression, suicide, criminal acts, and anti-social behaviors. Therefore, this study aims to analyze the effects of experiencing negative parental rearing behaviors, such as neglect and abuse, on adolescents' social withdrawal and aggression, by utilizing multivariate latent growth models...
September 2017: Korean Journal of Family Medicine
https://www.readbyqxmd.com/read/29023582/presence-of-children-in-the-home-and-intimate-partner-violence-among-women-seeking-elective-pregnancy-termination
#8
Corinne Peek-Asa, Audrey F Saftlas, Anne B Wallis, Karisa Harland, Penny Dickey
INTRODUCTION: Growing evidence identifies adverse health effects for children who witness intimate partner violence at home. Research has also identified that women seeking elective pregnancy termination are at high risk for partner violence. However, little is known about the risk for violence exposure among the children of women seeking elective pregnancy termination. METHODS: We conducted a cross-sectional study of 957 women seeking elective pregnancy termination at a large family planning clinic...
2017: PloS One
https://www.readbyqxmd.com/read/29017558/stress-health-and-quality-of-life-of-female-migrant-domestic-workers-in-singapore-a-cross-sectional-study
#9
S G Anjara, L B Nellums, C Bonetto, T Van Bortel
BACKGROUND: There is a global increase in migrant workers. In Singapore, there are over 230,000 migrant domestic workers (MDWs). Female MDWs may experience high levels of stress and social isolation, which may negatively impact on their health and quality of life. There have also been documented cases of abuse and exploitation. However, there is a lack of empirical research with this population. This study aimed to investigate factors impacting on the health and quality of life of female MDWs in Singapore, including socio-demographic and job related characteristics, stress, social isolation, and working management style...
October 10, 2017: BMC Women's Health
https://www.readbyqxmd.com/read/29017139/do-serum-bdnf-levels-vary-in-self-harm-behavior-among-adolescents-and-are-they-correlated-with-traumatic-experiences
#10
Canem Kavurma, Fatma Varol Tas, Burcu Serim Demirgoren, Ferhat Demirci, Pınar Akan, Damla Eyuboglu, Taner Guvenir
The aim of this study was to compare serum brain-derived neurotrophic factor (BDNF) levels between adolescents that harm themselves, those that receive psychiatric treatment but do not harm themselves, healthy adolescents, and childhood traumas and to investigate the relationship between traumatic experiences and serum BDNF levels. The cases were divided into two groups of 40 adolescents exhibiting self-harm behavior (self-harm/diagnosed group) and 30 adolescents receiving psychiatric treatment but not exhibiting self-harm behaviors (non self-harm/diagnosed group)...
September 28, 2017: Psychiatry Research
https://www.readbyqxmd.com/read/29016159/an-examination-of-the-test-retest-reliability-of-the-ace-sq-in-a-sample-of-college-athletes
#11
Danielle C Zanotti, Emily Kaier, Renee Vanasse, Joanne L Davis, Kathleen C Strunk, Lisa DeMarni Cromer
OBJECTIVE: The Adverse Childhood Experiences (ACE) study is one of the largest studies ever conducted that has examined the relationship of childhood abuse, neglect, and family dysfunction to subsequent health and well-being later in life. Questions from the ACE study evolved into the ACE Study Questionnaire, a measure used for assessing individuals' self-reported experiences of childhood adversity. The ACE measure is widely available and the Centers for Disease Control and Prevention (CDC) recommends it as a tool for assessing one's lifetime risk of mental and physical health problems and other negative social problems...
October 9, 2017: Psychological Trauma: Theory, Research, Practice and Policy
https://www.readbyqxmd.com/read/28990206/child-maltreatment-and-eating-disorders-among-men-and-women-in-adulthood-results-from-a-nationally-representative-united-states-sample
#12
Tracie O Afifi, Jitender Sareen, Janique Fortier, Tamara Taillieu, Sarah Turner, Kristene Cheung, Christine A Henriksen
OBJECTIVE: Child maltreatment is associated with an increased likelihood of having mood disorders, anxiety disorders, post-traumatic stress disorder, substance use disorders, and personality disorders, but far less is known about eating disorders. The objective of the current study was to examine the associations between child maltreatment, including harsh physical punishment, physical abuse, sexual abuse, emotional abuse, emotional neglect, physical neglect, and exposure to intimate partner violence, and eating disorders in adulthood among men and women...
October 9, 2017: International Journal of Eating Disorders
https://www.readbyqxmd.com/read/28985958/a-scoping-review-of-evidence-based-interventions-available-to-parents-of-maltreated-children-ages-0-5-involved-with-child-welfare-services
#13
Ashley L Landers, Alan McLuckie, Robin Cann, Valerie Shapiro, Sarah Visintini, Bruce MacLaurin, Nico Trocmé, Michael Saini, Normand J Carrey
Parents referred to child welfare services for child maltreatment often struggle against chronic risk factors including violence, substance abuse, mental health concerns, and poverty, which impinge upon their ability to be sensitive caregivers. The first line of intervention within the child welfare context is to modify parenting behavior. This scoping review comprehensively surveyed all available literature to map the extent and range of research activity around the types of interventions available within a child welfare context to parents of infants and toddlers (0-5 years of age), to identify the facilitators and/or barriers to the uptake of interventions, and to check that interventions match the risk factors faced by parents...
October 3, 2017: Child Abuse & Neglect
https://www.readbyqxmd.com/read/28985149/the-moderating-effect-of-interaction-avoidance-between-abusive-supervision-and-subordinates-job-promotions
#14
Vesa Peltokorpi
While abusive supervision is shown to have negative stress-related effects on targets, less is known about the factors capable of mitigating these negative effects and their career-related outcomes. In this paper, we drew on the transactional model of stress and coping (Lazarus & Folkman, 1986) and the upward mobility theory (Turner, 1960) to explore the moderating effect of subordinates' interaction avoidance between abusive supervision and job promotions. To test this moderating effect, we collected data from 604 full-time employees at three points in time over a 12-month time period in Japan...
October 6, 2017: Journal of Psychology
https://www.readbyqxmd.com/read/28983184/examination-of-the-extent-to-which-employment-factors-are-associated-with-reduced-child-maltreatment-potential-and-drug-use
#15
Brad Donohue, Christopher P Plant, Kimberly A Barchard, David J Gillis
Job assistance programs are commonly recommended for parents of children who have been victimized by child maltreatment, particularly when illicit drugs are indicated. However, the relationship between employment factors, substance abuse and risk of child maltreatment has received limited empirical attention. Therefore, the current study examines employment factors in a sample of 72 mothers who were referred by Child Protective Services (CPS) for treatment of substance abuse and child neglect. Child maltreatment potential was found to be negatively associated with number of hours employed and self-reported happiness with employment...
January 2017: Journal of Child and Family Studies
https://www.readbyqxmd.com/read/28981317/an-analysis-of-avoidant-and-approach-coping-as-mediators-of-the-relationship-between-paternal-and-maternal-attachment-security-and-outcomes-in-child-victims-of-sexual-abuse
#16
Martine Hébert, Marie-Ève Daspe, Mireille Cyr
OBJECTIVE: Prior studies have documented the potential role of nonoffending parent support in promoting recovery of adult survivors following sexual abuse (SA). However, few studies have distinguished the maternal and paternal role and the mechanisms by which quality of the parent-child relationship might foster more positive outcomes in child victims. The purpose of this study was to examine coping strategies as mediators of the link between mother-child and father-child relationship and outcomes following child SA...
October 5, 2017: Psychological Trauma: Theory, Research, Practice and Policy
https://www.readbyqxmd.com/read/28979752/triangular-relationship-among-risky-sexual-behavior-addiction-and-aggression-a-systematic-review
#17
REVIEW
Khodabakhsh Ahmadi, Seyed Alireza Javadinia, Seyed Hassan Saadat, Mohammad Arash Ramezani, Homa Sedghijalal
BACKGROUND: Risky sexual behavior (RSB), addiction, and aggression are three important personal and social factors which influence each other. OBJECTIVE: To overview the potential relationship among RSB, addiction, and aggression to conduct an interactive model for the pathology and management of human behavior. METHODS: This review article was carried out by searching studies in PubMed, Medline, Web of Science, Ebsco, IEEE, Scopus, Springer, MagIran, and IranMedex databases from the year 1993 to 2013...
August 2017: Electronic Physician
https://www.readbyqxmd.com/read/28977323/degradation-of-parental-bonding-and-violence-against-children-the-use-of-family-genogram-in-the-pediatric-clinic
#18
Égle Thomaz Leoncio, Sonia Regina Pereira de Souza, José Lúcio Martins Machado
OBJECTIVE: To demonstrate the importance of using the family genogram in pediatric consultation, as an analysis tool to evaluate the degradation of parental bonding and also violence against children. METHODS: A qualitative study was conducted in 2011 wherein 63 children, aged between 2 and 6 years, enrolled in a slum nursery, was studied. In order to construct the genogram, data were collected in four stages: pediatric evaluation at nursery; interview with caregivers; interview with teachers; and interview with the nursery coordinator...
April 2017: Revista Paulista de Pediatria: Orgão Oficial da Sociedade de Pediatria de São Paulo
https://www.readbyqxmd.com/read/28974320/the-mitigating-effects-of-maternal-social-support-and-paternal-involvement-on-the-intergenerational-transmission-of-violence
#19
Melissa Tracy, Madeleine Salo, Allison A Appleton
Childhood maltreatment is a strong risk factor for subsequent violence, including violent behaviors in young adulthood and offspring maltreatment after becoming a parent. Little is known about the specific circumstances under which supportive relationships may help disrupt this cycle of violence throughout the life course. We conducted two complementary analyses to assess whether maternal social support in early childhood, and also paternal involvement in middle childhood, could prevent the intergenerational transmission of violence, using data from the Avon Longitudinal Study of Parents and Children (n=11,384)...
September 30, 2017: Child Abuse & Neglect
https://www.readbyqxmd.com/read/28972456/child-sexual-abuse-and-intimate-partner-violence-victimization-in-adulthood-sex-differences-in-the-mediating-influence-of-age-of-sexual-initiation
#20
Timothy O Ihongbe, Saba W Masho
Child sexual abuse is a major public health concern in the United States with devastating sequelae. Although the relationship between child sexual abuse and intimate partner violence victimization in adulthood is known, little is known about the mediating influence of the age of sexual initiation on the association, or whether sex differences exist. Using data from waves I, III, and IV of the National Longitudinal Study of Adolescent to Adult Health (N = 1,163), we aimed to examine the mediating influence of age of sexual initiation on the association between child sexual abuse and intimate partner violence victimization in adulthood and identify sex differences...
October 3, 2017: Journal of Child Sexual Abuse
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