Niora J Fabian, Anthony J Mannion, Morgan Jamiel, David J Anderson, Joseph E Rower, Christopher A Reilly, William Menegas, Sureshkumar Muthupalani, Christina Ta, James G Fox, Robin Kramer, Jennifer L Haupt
While sustained-release buprenorphine (BSR) is used as a long-lasting opioid analgesic in common marmosets (Callithrix jacchus), there are no published studies on pharmaceutical-grade extended-release buprenorphine options such as Ethiqa XR (EXR) for this species. However, BSR is a compounded product and has been reported to cause injection site reactions in multiple species, including marmosets. Additionally, now with the availability of EXR, a pharmaceutical-grade veterinary product, the use of BSR in laboratory animals is not compliant with the Guide for the Care and Use of Laboratory Animals (Guide) unless scientifically justified and approved by the IACUC...
July 22, 2023: Scientific Reports