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https://www.readbyqxmd.com/read/28528981/development-and-validation-of-a-daily-pain-catastrophizing-scale
#1
Beth D Darnall, John A Sturgeon, Karon F Cook, Chloe J Taub, Anuradha Roy, John W Burns, Michael Sullivan, Sean C Mackey
To date, there is no validated measure for pain catastrophizing at the daily level. The Pain Catastrophizing Scale (PCS) is widely used to measure trait pain catastrophizing. We sought to develop and validate a brief, daily version of the PCS for use in daily diary studies in order to facilitate research on mechanisms of catastrophizing treatment, individual differences in self-regulation, and to reveal the nuanced relationships between catastrophizing, correlates, and pain outcomes. After adapting the PCS for daily use, we evaluated the resulting 14 items using 3 rounds of cognitive interviews with 30 adults with chronic pain...
May 18, 2017: Journal of Pain: Official Journal of the American Pain Society
https://www.readbyqxmd.com/read/28499360/prevalence-and-correlates-of-cognitive-impairment-in-kidney-transplant-recipients
#2
Aditi Gupta, Jonathan D Mahnken, David K Johnson, Tashra S Thomas, Dipti Subramaniam, Tyler Polshak, Imran Gani, G John Chen, Jeffrey M Burns, Mark J Sarnak
BACKGROUND: There is a high prevalence of cognitive impairment in dialysis patients. The prevalence of cognitive impairment after kidney transplantation is unknown. METHODS: Study Design: Cross-sectional study. SETTING AND PARTICIPANTS: Single center study of prevalent kidney transplant recipients from a transplant clinic in a large academic center. INTERVENTION: Assessment of cognition using the Montreal Cognitive Assessment (MoCA)...
May 12, 2017: BMC Nephrology
https://www.readbyqxmd.com/read/28494261/relationship-between-physical-performance-and-self-reported-function-in-healthy-individuals-across-the-lifespan
#3
Jennifer N Baldwin, Marnee J McKay, Claire E Hiller, Niamh Moloney, Elizabeth J Nightingale, Joshua Burns
BACKGROUND: Functional outcome measures in clinical trials of musculoskeletal conditions need to be meaningful to individuals. OBJECTIVES: To investigate the relationship between physical performance and self/proxy-reported function in 1000 healthy children and adults. DESIGN: Cross-sectional observational study (1000 Norms Project). METHODS: One thousand males and females aged 3-101 years, healthy by self-report and without major physical disability, were recruited...
May 2, 2017: Musculoskeletal Science & Practice
https://www.readbyqxmd.com/read/28489283/inflammatory-responses-matrix-remodeling-and-re-epithelialization-after-fractional-co2-laser-treatment-of-scars
#4
Danielle M DeBruler, Britani N Blackstone, Molly E Baumann, Kevin L McFarland, Brian C Wulff, Traci A Wilgus, J Kevin Bailey, Dorothy M Supp, Heather M Powell
BACKGROUND AND OBJECTIVE: Fractional CO2 laser therapy has been used to improve scar pliability and appearance; however, a variety of treatment protocols have been utilized with varied outcomes. Understanding the relationship between laser power and extent of initial tissue ablation and time frame for remodeling could help determine an optimum power and frequency for laser treatment. The characteristics of initial injury caused by fractional CO2 laser treatment, the rates of dermal remodeling and re-epithelialization, and the extent of inflammation as a function of laser stacking were assessed in this study in a porcine scar model...
May 10, 2017: Lasers in Surgery and Medicine
https://www.readbyqxmd.com/read/28483656/two-year-gender-differences-in-satisfaction-with-appearance-after-burn-injury-and-prediction-of-five-year-depression-a-latent-growth-curve-approach
#5
Nour Al Ghriwati, Megan Sutter, Bradford S Pierce, Paul B Perrin, Shelley A Wiechman, Jeffrey C Schneider
OBJECTIVE: To use latent growth curve and longitudinal structural equation modeling to examine the two-year trajectory of satisfaction with appearance in adults with burn injury and that trajectory's effect on depression five years after burn injury. DESIGN: Data were collected at discharge after burn injury hospitalization, six months, one year, two years, and five years post-discharge. SETTING: The Burn Model System (BMS) program consisted of a data center and five participating burn centers...
May 5, 2017: Archives of Physical Medicine and Rehabilitation
https://www.readbyqxmd.com/read/28481758/building-bridges-using-the-shriners-hospitals-for-children-american-burn-association-burn-outcome-questionnaires-to-follow-teenagers-and-young-adults-across-the-age-spans
#6
Aaron J Kaat, Liang Chen, Lewis E Kazis, Austin F Lee, Gabriel D Shapiro, Robert L Sheridan, Colleen M Ryan, Jeffrey C Schneider
The Shriners Hospitals for Children/American Burn Association Burn Outcomes Questionnaires (BOQ) are well-established, reliable, and valid outcome measures. The adolescent (BOQ11-18 years) and young adult version (18-30 years) have similar overlapping domains, but the scores are not comparable. This study objective was to build bridges across these forms. Datasets were from the Multi-Center Benchmarking Study Group. The comparable subscales from the BOQ11-18 and the young adult version were bridged using item response theory cocalibration...
May 4, 2017: Journal of Burn Care & Research: Official Publication of the American Burn Association
https://www.readbyqxmd.com/read/28476075/drugs-for-discoid-lupus-erythematosus
#7
REVIEW
Sue Jessop, David A Whitelaw, Matthew J Grainge, Prativa Jayasekera
BACKGROUND: Discoid lupus erythematosus (DLE) is a chronic form of cutaneous lupus, which can cause scarring. Many drugs have been used to treat this disease and some (such as thalidomide, cyclophosphamide and azathioprine) are potentially toxic. This is an update of a Cochrane Review first published in 2000, and previously updated in 2009. We wanted to update the review to assess whether any new information was available to treat DLE, as we were still unsure of the effectiveness of available drugs and how to select the most appropriate treatment for an individual with DLE...
May 5, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28467535/association-of-the-modified-frailty-index-with-30-day-surgical-readmission
#8
Tyler S Wahl, Laura A Graham, Mary T Hawn, Joshua Richman, Robert H Hollis, Caroline E Jones, Laurel A Copeland, Edith A Burns, Kamal M Itani, Melanie S Morris
Importance: Frail patients are known to have poor perioperative outcomes. There is a paucity of literature investigating how the Modified Frailty Index (mFI), a validated measure of frailty, is associated with unplanned readmission among military veterans following surgery. Objective: To understand the association between frailty and 30-day postoperative unplanned readmission. Design, Setting, and Participants: A retrospective cohort study was conducted among adult patients who underwent surgery and were discharged alive from Veterans Affairs hospitals for orthopedic, general, and vascular conditions between October 1, 2007, and September 30, 2014, with a postoperative length of stay between 2 and 30 days...
May 3, 2017: JAMA Surgery
https://www.readbyqxmd.com/read/28456851/ruxolitinib-reduces-jak2-p-v617f-allele-burden-in-patients-with-polycythemia-vera-enrolled-in-the-response-study
#9
Alessandro Maria Vannucchi, Srdan Verstovsek, Paola Guglielmelli, Martin Griesshammer, Timothy C Burn, Ahmad Naim, Dilan Paranagama, Mahtab Marker, Brian Gadbaw, Jean-Jacques Kiladjian
In patients with polycythemia vera (PV), an elevated JAK2 p.V617F allele burden is associated with indicators of more severe disease (e.g., leukocytosis, splenomegaly, and increased thrombosis risk); however, correlations between allele burden reductions and clinical benefit in patients with PV have not been extensively evaluated in a randomized trial. This exploratory analysis from the multicenter, open-label, phase 3 Randomized Study of Efficacy and Safety in Polycythemia Vera With JAK Inhibitor INCB018424 Versus Best Supportive Care trial evaluated the long-term effect of ruxolitinib treatment on JAK2 p...
April 30, 2017: Annals of Hematology
https://www.readbyqxmd.com/read/28455274/protocol-of-a-pilot-study-of-technology-enabled-coproduction-in-pediatric-chronic-illness-care
#10
Heather C Kaplan, Sunny Narendra Thakkar, Lisa Burns, Barbara Chini, Dana Mh Dykes, Gary L McPhail, Erin Moore, Shehzad Ahmed Saeed, Ian Eslick, Peter A Margolis, Lisa Opipari-Arrigan
BACKGROUND: Pediatric chronic illness care models are traditionally organized around acute episodes of care and may not meet the needs of patients and their families. Interventions that extend the patient-clinician interaction beyond the health care visit, allow for asynchronous and bidirectional feedback loops that span visits and daily life, and facilitate seamless sharing of information are needed to support a care delivery system that is more collaborative, continuous, and data-driven...
April 28, 2017: JMIR Research Protocols
https://www.readbyqxmd.com/read/28454533/associations-between-compulsory-community-treatment-and-continuity-of-care-in-a-three-year-follow-up-of-the-oxford-community-treatment-order-trial-octet-cohort
#11
Stephen Robert Puntis, Jorun Rugkåsa, Tom Burns
BACKGROUND: Most studies investigating the effectiveness of Community Treatment Orders (CTOs) use readmission to hospital as the primary outcome. Another aim of introducing CTOs was to improve continuity of care. Our study was a 3-year prospective follow-up which tested for associations between CTOs and continuity of care. METHODS: Our study sample included 333 patients recruited to the Oxford Community Treatment Order Trial (OCTET). We collected data on continuity of care using eight previously operationalized measures...
April 28, 2017: BMC Psychiatry
https://www.readbyqxmd.com/read/28448718/cannabis-use-by-women-during-pregnancy-does-not-influence-infant-dna-methylation-of-the-dopamine-receptor-drd4
#12
Peter D Fransquet, Delyse Hutchinson, Craig A Olsson, Steve Allsop, Elizabeth J Elliott, Lucinda Burns, Richard Mattick, Richard Saffery, Joanne Ryan
BACKGROUND: Maternal cannabis use in pregnancy is linked with long-term adverse behavioral outcomes in offspring. Epigenetic processes established in utero that affect dopaminergic (reward) signaling may mediate risks. Associations between cannabis use and offspring DNA methylation have not been investigated; however, maternal tobacco smoking in pregnancy is associated with distinct patterns of DNA methylation at birth and beyond. OBJECTIVES: To determine whether maternal cannabis use is associated with methylation of the dopamine receptor gene DRD4 promoter in infants...
April 27, 2017: American Journal of Drug and Alcohol Abuse
https://www.readbyqxmd.com/read/28442165/technical-tips-to-enhance-micrografting-results-in-burn-surgery
#13
Si Jack Chong, Abby Choke, Bien-Keem Tan
The lack of autograft donor site is one of the greatest limiting factors for the treatment of extensive burn. Micrografting is an important revolution in burn surgery where autografts are cut into small pieces for wide and rapid coverage of burn wound. Our early experiences with the current standard micrografting technique were fraught with poor graft take as well being time and labor intensive. We have improvised our technique, where we combined the use of allograft to serve as a carrier for the micrograft...
April 22, 2017: Burns: Journal of the International Society for Burn Injuries
https://www.readbyqxmd.com/read/28433345/the-effect-of-pre-existing-malnutrition-on-pediatric-burn-mortality-in-a-sub-saharan-african-burn-unit
#14
Joanna Grudziak, Carolyn Snock, Stephen Mjuweni, Jared Gallaher, Bruce Cairns, Anthony Charles
INTRODUCTION: Nutritional status predicts burn outcomes in the developed world, but its effect on burn mortality in the developing world has not been widely studied. In sub Saharan Africa, burn is primarily a disease of children, and the majority of children in sub-Saharan Africa are malnourished. We therefore sought to determine the prevalence and effect of malnutrition on burn mortality at our institution. METHODS: This is a retrospective review of children aged 0-5, with anthropomorphic measurements available, who were admitted to our burn unit from July 2011 to May 2016...
April 19, 2017: Burns: Journal of the International Society for Burn Injuries
https://www.readbyqxmd.com/read/28420569/identification-of-factors-predicting-scar-outcome-after-burn-in-adults-a-prospective-case-control-study
#15
Hilary J Wallace, Mark W Fear, Margaret M Crowe, Lisa J Martin, Fiona M Wood
This study examined influences on scarring after burn in a prospective study using a defined outcome measure: scar height measured by a modified Vancouver Scar Scale (mVSS). A prospective case-control study was conducted among 616 adult subjects who sustained a burn in Western Australia. Patient factors influencing scar outcome including gender, Fitzpatrick skin type and selected co-morbidities were explored, as well as injury and clinical factors. A logistic regression model for raised scar after burn was developed which achieved an overall correct prediction rate of 81...
April 15, 2017: Burns: Journal of the International Society for Burn Injuries
https://www.readbyqxmd.com/read/28413088/a-retrospective-analysis-of-neurocognitive-impairment-in-older-patients-with-burn-injuries
#16
Emily G Holmes, Samuel W Jones, Sarah L Laughon
BACKGROUND: Older adults comprise a growing proportion of the United States population that is at risk for burns. However, few studies have examined cognitive function in this patient population. OBJECTIVE: The purpose of this study was to measure the prevalence and incidence of dementia and delirium in older adults admitted for burn injuries. METHODS: This was an Institutional Review Board-approved, retrospective study of all patients 65 years and older admitted to the University of North Carolina Jaycee Burn Center from 2005-2015...
March 6, 2017: Psychosomatics
https://www.readbyqxmd.com/read/28383066/epidemiology-and-outcome-analysis-of-6325-burn-patients-a-five-year-retrospective-study-in-a-major-burn-center-in-southwest-china
#17
Haisheng Li, Zhihui Yao, Jianglin Tan, Junyi Zhou, Yi Li, Jun Wu, Gaoxing Luo
Burns are a major cause of injury worldwide. We investigated the epidemiology and outcomes of burn patients in a major burn center in southwest China between 2011 and 2015 to provide guidance for burn prevention. Of the 6,325 included burn patients, 66.8% were male and 34.7% were 0 ~ 6 years old. The incidence of burns peaked in autumn. Scald was the most common cause of burns, which was predominant in patients aged 0 ~ 6 years. The mean total body surface area (TBSA) of burns was 13.4%, and patients with burns ≤10% TBSA comprised 64...
April 6, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28379160/epidemiology-of-burns-in-rural-bangladesh-an-update
#18
Siran He, Olakunle Alonge, Priyanka Agrawal, Shumona Sharmin, Irteja Islam, Saidur Rahman Mashreky, Shams El Arifeen
Each year, approximately 265,000 deaths occur due to burns on a global scale. In Bangladesh, around 173,000 children under 18 sustain a burn injury. Since most epidemiological studies on burn injuries in low and middle-income countries are based on small-scale surveys or hospital records, this study aims to derive burn mortality and morbidity measures and risk factors at a population level in Bangladesh. A household survey was conducted in seven rural sub-districts of Bangladesh in 2013 to assess injury outcomes...
April 5, 2017: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/28377523/delivering-strong-1-h-nuclear-hyperpolarization-levels-and-long-magnetic-lifetimes-through-signal-amplification-by-reversible-exchange
#19
Peter J Rayner, Michael J Burns, Alexandra M Olaru, Philip Norcott, Marianna Fekete, Gary G R Green, Louise A R Highton, Ryan E Mewis, Simon B Duckett
Hyperpolarization turns typically weak NMR and MRI responses into strong signals so that ordinarily impractical measurements become possible. The potential to revolutionize analytical NMR and clinical diagnosis through this approach reflect this area's most compelling outcomes. Methods to optimize the low-cost parahydrogen-based approach signal amplification by reversible exchange with studies on a series of biologically relevant nicotinamides and methyl nicotinates are detailed. These procedures involve specific (2)H labeling in both the agent and catalyst and achieve polarization lifetimes of ca 2 min with 50% polarization in the case of methyl-4,6-d2 -nicotinate...
April 18, 2017: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/28373062/a-summer-health-program-for-african-american-high-school-students-in-baltimore-maryland-community-partnership-for-integrative-health
#20
Beverly Pierce, Brandin Bowden, Molly McCullagh, Alica Diehl, Zachary Chissell, Rebecca Rodriguez, Brian M Berman, Christopher R D Adamo
CONTEXT: Physical inactivity, poor nutrition, and chronic stress threaten the health of African-American youth in urban environments. Conditions often worsen in summer with diminished access to healthy foods and safe venues for physical activity. OBJECTIVE: A public-private partnership was formed to develop and evaluate an integrative health intervention entitled "Mission Thrive Summer" (MTS). METHODS: The MTS setting was an urban farm and adjacent school in a low-income community in Baltimore, Maryland...
February 24, 2017: Explore: the Journal of Science and Healing
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