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https://www.readbyqxmd.com/read/28874080/low-molecular-weight-gel-fraction-of-aloe-vera-exhibits-gastroprotection-by-inducing-matrix-metalloproteinase-9-inhibitory-activity-in-alcohol-induced-acute-gastric-lesion-tissues
#1
Chul-Hong Park, Hyeong-U Son, Chi-Yeol Yoo, Sang-Han Lee
CONTEXT: Aloe has been used for the prevention and cure of various diseases and symptoms including burns, injuries, oedema and pain. OBJECTIVE: This study determines the specific inhibitory activity of matrix metalloproteinase (MMP)-9 induced by the low molecular-weight gel fraction of Aloe vera (L.) Burm.f. (lgfAv) on alcohol-induced acute gastric lesions. MATERIALS AND METHODS: We examined the protective effects of oral (p.o.) administration of lgfAv (molecular weight cutoff <50...
December 2017: Pharmaceutical Biology
https://www.readbyqxmd.com/read/28844655/a-missed-diagnosis-of-multiple-intraocular-foreign-bodies-for-21-years
#2
Xubo Yang, Chunling Liu, Longqian Liu, Lanlan Zhang
A 30-year-old patient went to the emergency department because of a chemical burn to the left eye more than 10 days ago by toilet cleanser. Surprisingly, a small piece of glass was found in the inferior anterior chamber in the same eye. The visual acuity was counting fingers. There was conjunctival congestion, corneal oedema and Descemet's membrane striae. And there was also a corneal leukoma around 4 to 5 o'clock. Through repeated questioning he recalled that he was injured by an exploded light bulb around 21 years ago...
August 24, 2017: Contact Lens & Anterior Eye: the Journal of the British Contact Lens Association
https://www.readbyqxmd.com/read/28600109/the-cardio-respiratory-effects-of-intra-abdominal-hypertension-considerations-for-critical-care-nursing-practice
#3
REVIEW
Martin Christensen, Judy Craft
Intra-abdominal hypertension can be classified as either primary or secondary. Primary intra-abdominal hypertension is often associated through trauma or diseases of the abdominopelvic region such as pancreatitis or abdominal surgery, while secondary intra-abdominal hypertension is the result of extra-abdominal causes such as sepsis or burns. The critically ill patient offers some challenges in monitoring in particular secondaryintra-abdominal hypertension because of the effects of fluid resuscitation, the use of inotropes and positive pressure ventilation...
June 6, 2017: Intensive & Critical Care Nursing: the Official Journal of the British Association of Critical Care Nurses
https://www.readbyqxmd.com/read/28367792/safety-and-efficacy-of-current-alternatives-in-the-topical-treatment-of-cutaneous-leishmaniasis-a-systematic-review
#4
Priscila Wolf Nassif, Tatiane França Perles DE Mello, Taísa Rocha Navasconi, Camila Alves Mota, Izabel Galhardo Demarchi, Sandra Mara Alessi Aristides, Maria Valdrinez Campana Lonardoni, Jorge Juarez Vieira Teixeira, Thaís Gomes Verzignassi Silveira
Studies of topical treatments for leishmaniasis were systematically reviewed, to evaluate the therapeutic efficacy, safety and any adverse effects of these treatments. The papers identified in the databases PubMed and Web of Knowledge involved eight studies with a total of 1744 patients. The majority of trials was from Iran (4/8), covered a period of 8 years (2003-2011), and included patients 4-85 years of age. The most frequent Leishmania species in the studies were L. tropica (4/8) and L. major (2/8). The treatments administered were thermotherapy, paromomycin and combinations, CO2 laser, 5-aminolevulinic acid hydrochloride (10%) plus visible red light (633 nm) and cryotherapy...
April 3, 2017: Parasitology
https://www.readbyqxmd.com/read/28258097/lung-ultrasound-a-useful-tool-in-the-assessment-of-the-dyspnoeic-patient-in-the-emergency-department-fact-or-fiction
#5
REVIEW
Yashvi Wimalasena, Laura Kocierz, Dan Strong, Joanna Watterson, Brian Burns
Patients with respiratory distress present a frequent and challenging dilemma for emergency physicians (EPs). The accurate diagnosis and treatment of the underlying pathology is vitally important in these sick patients to ensure the best outcome and minimise harm from unnecessary treatments. Within the last decade, studies have shown lung ultrasonography (LU) to be valuable in the accurate diagnosis of a variety of lung pathologies, including cardiogenic pulmonary oedema, pleural effusion, pneumothorax, haemothorax and pneumonia...
March 3, 2017: Emergency Medicine Journal: EMJ
https://www.readbyqxmd.com/read/28208899/study-of-variation-in-intraocular-pressure-spike-iop-following-nd-yag-laser-capsulotomy
#6
Niharika K Shetty, Sriya Sridhar
INTRODUCTION: Posterior Capsular Opacifications (PCO) is a frequent complication of cataract surgery following posterior chamber intraocular lens implantation. Nd -Yag laser capsulotomy is the treatment of choice for PCO and is known to be associated with complications like Raised Intraocular Pressure (IOP), Intraocular lens pitting, intraocular lens cracks, cystoid macular oedema, retinal detachment, corneal burns. Raised IOP is the most common complication and prescribing anti-glaucoma drugs post capsulotomy is a common practise...
December 2016: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28191804/does-alternative-and-traditional-wasam-local-cautery-therapy-facilitate-an-early-and-more-extensive-locoregional-metastasis-of-breast-cancer
#7
(no author information available yet)
INTRODUCTION: A large heterogeneous group of unproven remedies exist to treat cancer in both developed and developing countries. Some of these remedies often do more harm than good to the patients. The traditional medicine is the sum total of the knowledge, skills, and practices based on the theories, beliefs, and experiences indigenous to different cultures. The traditional medicine in Oman is based on herbal treatment and skin treatment (massage, Cupping and skin burn "cautery" treatment-known as Wasam or Kaiy)...
September 2016: Gulf Journal of Oncology
https://www.readbyqxmd.com/read/27801522/prophylactic-non-steroidal-anti-inflammatory-drugs-for-the-prevention-of-macular-oedema-after-cataract-surgery
#8
REVIEW
Blanche X Lim, Chris Hl Lim, Dawn K Lim, Jennifer R Evans, Catey Bunce, Richard Wormald
BACKGROUND: Macular oedema (MO) is the accumulation of extracellular fluid in the central retina (the macula). It may occur after cataract surgery and may give rise to poor visual outcome, with reduced visual acuity and distortion of the central vision. MO is often self-limiting with spontaneous resolution, but a small proportion of people with chronic persistent MO may be difficult to treat. Chronic oedema may lead to the formation of cystic spaces in the retina termed 'cystoid macular oedema' (CMO)...
November 1, 2016: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/27672133/quenching-tank-accidental-drowning-in-hot-quenching-oil
#9
Anand B Mugadlimath, Mandar Ramchandra Sane, Kailash U Zine, Rekha M Hiremath
We describe an unusual case of drowning in fluid other than water in an industrial setting. A 26-year-old man was working in an industry which performs surface treatment of mechanical steel parts with quenching oil. He fell into the quenching oil (which was hot due to immersion of red hot metal parts), and as he was working alone in the particular section, there was a fatal outcome. A medico-legal autopsy was performed. The causes of death were found to be multiple, with the association of drowning, extensive superficial burns and asphyxia due to laryngeal oedema...
September 26, 2016: Medico-legal Journal
https://www.readbyqxmd.com/read/27547959/use-of-negative-pressure-wound-therapy-in-burn-patients
#10
Shou-Cheng Teng
According to previous research, adjunctive negative pressure wound therapy (NPWT) can help manage infected wounds when applied along with appropriate debridement and antibiotic therapy as deemed clinically relevant. NPWT not only removes fluid, and reduces oedema, but also promotes perfusion around the wounds. In addition, NPWT may lead to improved graft fixation when used as a bolster, especially in patients who are less compliant or have poor graft fixation that result from using traditional methods. NPWT is a good choice to bolster skin grafts in young, active and less-compliant patients...
September 2016: International Wound Journal
https://www.readbyqxmd.com/read/27183931/sub-threshold-frequency-doubled-nd-yag-modified-mild-maculr-grid-laser-for-diffuse-diabetic-maculopathy
#11
Jamshed Ahmed, Rommana Fasih
OBJECTIVE: To determine the anatomical and functional improvement in eyes with diffuse macular oedema after modified mild macular grid laser. METHODS: The prospective study was conducted at the Department of Ophthalmology Unit II, Civil Hospital Karachi, and the Department of Ophthalmology, Dow International Medical College, Karachi, from June 2011 to May 2014. We used neodymium-doped yttrium aluminium garnet 532nm frequency-doubled green laser to treat all eligible patients...
May 2016: JPMA. the Journal of the Pakistan Medical Association
https://www.readbyqxmd.com/read/26847049/the-utility-of-the-high-resolution-ultrasound-technique-in-the-evaluation-of-autologous-adipose-tissue-lipofilling-used-for-the-correction-of-post-surgical-post-traumatic-and-post-burn-scars
#12
Maria Scotto di Santolo, Marco Sagnelli, Giovanni Tortora, Maria Angela Santoro, Pier Luigi Canta, Guido Molea, Fabrizio Schonauer, Massimo Imbriaco
PURPOSE: Lipofilling technique is significantly increasing and the need of a non-invasive method to assess the success of the procedure is becoming mandatory. In particular, US can be considered an alternative method to MRI for evaluation of tissue lipofilling due to the simplicity and easy access of the technique and can be also used for monitoring the efficacy of the surgical procedure. The goal of this study was to demonstrate, the utility of the high-resolution ultrasound technique in the evaluation of autologous adipose tissue lipofilling, used for the correction of post-surgical, post-traumatic and post-burn scars...
June 2016: La Radiologia Medica
https://www.readbyqxmd.com/read/26774605/management-of-the-lower-gastrointestinal-system-in-burn-a-comprehensive-review
#13
REVIEW
J W G Ng, S A Cairns, C P O'Boyle
BACKGROUND: Burn produces complex gastrointestinal (GI) responses. Treatment, including large volume fluid resuscitation and opioid analgesia, may exacerbate GI dysfunction. Complications include constipation and opioid-induced bowel dysfunction (OBD), acute colonic pseudo-obstruction (ACPO), bacterial translocation and sepsis, and abdominal compartment syndrome (ACS). Contamination of perineal burns contributes to delayed healing, skin graft failure and sepsis and may impact upon morbidity and mortality...
June 2016: Burns: Journal of the International Society for Burn Injuries
https://www.readbyqxmd.com/read/26712289/a-corrosive-oesophageal-burn-model-in-rats-double-lumen-central-venous-catheter-usage
#14
Vedat Bakan, Harun Ciralik, Seyfi Kartal
BACKGROUND: We aimed to create a new and less invasive experimental corrosive oesophageal burn model using a catheter without a gastric puncture (gastrotomy). MATERIALS AND METHODS: We conducted the study with two groups composed of 8 male rats. The experimental oesophageal burn was established by the application of 10% sodium hydroxide to the distal oesophagus under a pressure of 20 cmH 2 O, via 5-F double-lumen central venous catheter without a gastrotomy. The control group was given 0...
October 2015: African Journal of Paediatric Surgery: AJPS
https://www.readbyqxmd.com/read/26554271/clinicopathological-effects-of-pepper-oleoresin-capsicum-spray
#15
REVIEW
M F Yeung, William Y M Tang
OBJECTIVES: Pepper (oleoresin capsicum) spray is one of the most common riot-control measures used today. Although not lethal, exposure of pepper spray can cause injury to different organ systems. This review aimed to summarise the major clinicopathological effects of pepper spray in humans. DATA SOURCES: MEDLINE, EMBASE database, and Cochrane Database of Systematic Reviews were used to search for terms associated with the clinicopathological effects of pepper spray in humans and those describing the pathophysiology of capsaicin...
December 2015: Hong Kong Medical Journal, Xianggang Yi Xue za Zhi
https://www.readbyqxmd.com/read/26266908/the-effect-of-vitamin-c-on-plasma-volume-in-the-early-stage-of-sepsis-in-the-rat
#16
Björn P Bark, Per-Olof Grände
BACKGROUND: Previous experimental studies have shown that vitamin C has several beneficial effects in sepsis and burns, such as decreased tissue oedema, improved endothelial barrier function and decreased transcapillary leakage of plasma markers. It has still not been investigated, though, if vitamin C has any impact specifically on plasma volume. The present study aims at testing the hypothesis that vitamin C decreases plasma volume loss in sepsis. METHODS: Anaesthetized male adult Sprague-Dawley rats were used in this prospective randomized study...
December 2014: Intensive Care Medicine Experimental
https://www.readbyqxmd.com/read/26173799/pan-retinal-photocoagulation-and-other-forms-of-laser-treatment-and-drug-therapies-for-non-proliferative-diabetic-retinopathy-systematic-review-and-economic-evaluation
#17
REVIEW
Pamela Royle, Hema Mistry, Peter Auguste, Deepson Shyangdan, Karoline Freeman, Noemi Lois, Norman Waugh
BACKGROUND: Diabetic retinopathy is an important cause of visual loss. Laser photocoagulation preserves vision in diabetic retinopathy but is currently used at the stage of proliferative diabetic retinopathy (PDR). OBJECTIVES: The primary aim was to assess the clinical effectiveness and cost-effectiveness of pan-retinal photocoagulation (PRP) given at the non-proliferative stage of diabetic retinopathy (NPDR) compared with waiting until the high-risk PDR (HR-PDR) stage was reached...
July 2015: Health Technology Assessment: HTA
https://www.readbyqxmd.com/read/26095255/systematic-review-of-high-intensity-focused-ultrasound-ablation-in-the-treatment-of-breast-cancer
#18
REVIEW
M C L Peek, M Ahmed, A Napoli, B ten Haken, S McWilliams, S I Usiskin, S E Pinder, M van Hemelrijck, M Douek
BACKGROUND: A systematic review was undertaken to assess the clinical efficacy of non-invasive high-intensity focused ultrasound (HIFU) ablation in the treatment of breast cancer. METHODS: MEDLINE/PubMed library databases were used to identify all studies published up to December 2013 that evaluated the role of HIFU ablation in the treatment of breast cancer. Studies were eligible if they were performed on patients with breast cancer and objectively recorded at least one clinical outcome measure of response (imaging, histopathological or cosmetic) to HIFU treatment...
July 2015: British Journal of Surgery
https://www.readbyqxmd.com/read/26024991/effects-of-cd25sirna-gene-transfer-on-high-risk-rat-corneal-graft-rejection
#19
Qin Qin, Yunjie Shi, Qingqing Zhao, Dan Luo, Yuan Chen, Jing Wu, Min Zhao
BACKGROUND: Corneal graft rejection is the major cause of corneal failures. Previous studies have shown that the CD25 monoclonal antibody can inhibit corneal graft rejection during the acute phase of rejection in rat models. In the current study, we evaluated the safety and efficacy of the topical Entranster™ vector in rat corneal applications and further investigated the effects of CD25siRNA gene transfer on high-risk rat corneal graft rejection. METHODS: Fluorescence detection, clinical assessment, hematoxylin and eosin (HE), terminal deoxynucleotidyl transferase biotin-dUTP nick end labelling (TUNEL) and CD11b assays were used to evaluate the safety and efficacy of CD25siRNA gene transfer in normal SD rat corneas...
October 2015: Graefe's Archive for Clinical and Experimental Ophthalmology
https://www.readbyqxmd.com/read/25939573/airway-compromise-in-children-with-anterior-neck-burns-beware-the-scalded-child
#20
Ela J Hyland, John G Harvey, Andrew J P Martin, Andrew J A Holland
AIM: The aim of the study was to describe characteristics of children with anterior neck burns admitted to our Paediatric Intensive Care Unit (PICU) and to highlight potential airway complications associated with these injuries, especially in children with scalds. METHODS: Retrospective review of children with anterior neck burns requiring admission to PICU January 2004-December 2013. RESULTS: Fifty-two children with anterior neck burns were admitted; average age 6...
October 2015: Journal of Paediatrics and Child Health
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