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https://www.readbyqxmd.com/read/28924674/spine-posture-influences-tactile-perceptual-sensitivity-of-the-trunk-dorsum
#1
Shawn M Beaudette, Simone G V S Smith, Leah R Bent, Stephen H M Brown
The purpose of the current work was to quantify the influence of posture-mediated skin deformation on trunk dorsum tactile perceptual sensitivity. Twelve young and healthy individuals were assessed while adopting three different spine postures (extension, neutral and flexion). Tactile sensitivity threshold tests (T10 and L4 vertebral levels) included measures of touch sensitivity, spatial acuity and stretch sensitivity. The results demonstrate that tactile sensitivity can differ due to changes in body posture...
September 18, 2017: Annals of Biomedical Engineering
https://www.readbyqxmd.com/read/28924119/triphasic-mitral-inflow-pattern-in-a-patient-with-congenital-absence-of-the-pericardium
#2
Masanobu Ishii, Ikuo Misumi, Tsuyoshi Honda, Taiyo Komatsu
A healthy 19-year-old man was referred to our hospital due to an elongated left heart border on chest radiograph. Transthoracic echocardiography showed a posteriorly deviated left ventricular apex, increased right ventricular dimension, and hypokinesis of the interventricular septum. Pulsed Doppler echocardiogram revealed a triphasic mitral inflow pattern. Myocardial longitudinal strain rate imaging revealed that the early diastolic strain rate abruptly decreased to a negative value and then became positive at the left ventricular apex...
September 15, 2017: Internal Medicine
https://www.readbyqxmd.com/read/28923405/positive-mood-on-the-day-of-influenza-vaccination-predicts-vaccine-effectiveness-a-prospective-observational-cohort-study
#3
Kieran Ayling, Lucy Fairclough, Paddy Tighe, Ian Todd, Vanessa Halliday, Jon Garibaldi, Simon Royal, Aljali Hamed, Heather Buchanan, Kavita Vedhara
Influenza vaccination is estimated to only be effective in 17-53% of older adults. Multiple patient behaviors and psychological factors have been shown to act as 'immune modulators' sufficient to influence vaccination outcomes. However, the relative importance of such factors is unknown as they have typically been examined in isolation. The objective of the present study was to explore the effects of multiple behavioral (physical activity, nutrition, sleep) and psychological influences (stress, positive mood, negative mood) on the effectiveness of the immune response to influenza vaccination in the elderly...
September 15, 2017: Brain, Behavior, and Immunity
https://www.readbyqxmd.com/read/28922650/constitutive-modeling-of-the-passive-inflation-extension-behavior-of-the-swine-colon
#4
Bhavesh Patel, Huan Chen, Aashish Ahuja, Joshua F Krieger, Jillian Noblet, Sean Chambers, Ghassan S Kassab
In the present work, we propose the first structural constitutive model of the passive mechanical behavior of the swine colon that is validated against physiological inflation-extension tests, and accounts for residual strains. Sections from the spiral colon and the descending colon were considered to investigate potential regional variability. We found that the proposed constitutive model accurately captures the passive inflation-extension behavior of both regions of the swine colon (coefficient of determination R(2)=0...
August 31, 2017: Journal of the Mechanical Behavior of Biomedical Materials
https://www.readbyqxmd.com/read/28917675/regional-variation-in-technetium-pyrophosphate-uptake-in-transthyretin-cardiac-amyloidosis-and-impact-on%C3%A2-mortality
#5
Brett W Sperry, Michael N Vranian, Albree Tower-Rader, Rory Hachamovitch, Mazen Hanna, Richard Brunken, Dermot Phelan, Manuel D Cerqueira, Wael A Jaber
OBJECTIVES: This study sought to investigate the regional uptake of technetium 99m-pyrophosphate (TcPYP) in transthyretin cardiac amyloidosis (ATTR) and its association with mortality. BACKGROUND: TcPYP nuclear scintigraphy is a diagnostic and prognostic tool in ATTR. Echocardiography has identified a pattern of regional variation in longitudinal strain (LS) with a gradient of improved strain from base to apex in ATTR. METHODS: Consecutive patients with ATTR were evaluated who underwent TcPYP nuclear scintigraphy with planar and attenuation corrected single-photon emission computed tomography (SPECT)...
September 9, 2017: JACC. Cardiovascular Imaging
https://www.readbyqxmd.com/read/28913656/new-insights-into-cardiac-involvement-in-juvenile-scleroderma-a-three-dimensional-echocardiographic-assessment-unveils-subclinical-ventricle-dysfunction
#6
Reyhan Dedeoglu, Amra Adroviç, Funda Oztunç, Sezgin Sahin, Kenan Barut, Ozgur Kasapcopur
Cardiac manifestations in juvenile scleroderma or systemic sclerosis (JSSc) have poor prognosis, begin in early stages of the disease, and remain clinically asymptomatic. New echocardiography modalities, such as 2D/3D speckle tracking (STE, strain analysis for regional and global ventricular functions), can detect cardiac involvement in early stages. We assessed 21 JSSc patients and 19 controls using 2D/3D STE. The left ventricular end diastolic volume, end systolic volume, and ejection fraction of the patient and control groups were significantly different (99...
September 14, 2017: Pediatric Cardiology
https://www.readbyqxmd.com/read/28912769/adaptation-of-surface-associated-bacteria-to-the-open-ocean-a-genomically-distinct-subpopulation-of-phaeobacter-gallaeciensis-colonizes-pacific-mesozooplankton
#7
Heike M Freese, Anika Methner, Jörg Overmann
The marine Roseobacter group encompasses numerous species which occupy a large variety of ecological niches. However, members of the genus Phaeobacter are specifically adapted to a surface-associated lifestyle and have so far been found nearly exclusively in disjunct, man-made environments including shellfish and fish aquacultures, as well as harbors. Therefore, the possible natural habitats, dispersal and evolution of Phaeobacter spp. have largely remained obscure. Applying a high-throughput cultivation strategy along a longitudinal Pacific transect, the present study revealed for the first time a widespread natural occurrence of Phaeobacter in the marine pelagial...
2017: Frontiers in Microbiology
https://www.readbyqxmd.com/read/28912359/left-ventricular-strain-rate-is-reduced-during-voluntary-apnea-in-healthy-humans
#8
Joshua R Smith, Shelbi L Sutterfield, Dryden R Baumfalk, Kaylin D Didier, Shane M Hammer, Jacob Troy Caldwell, Carl J Ade
During an apneic event, sympathetic nerve activity increases resulting in subsequent increases in left ventricular afterload and myocardial work. It is unknown how cardiac mechanics are acutely impacted by the increased myocardial work during an apneic event. 10 healthy individuals (23 ± 3 yrs) performed multiple voluntary end-expiratory apnea (VEEA) maneuvers exposed to room air, while a subset (n=7) completed multiple VEEA exposed to hyperoxic air (100% FiO2). Beat-by-beat blood pressure, heart rate and stroke volume were measured continuously...
September 14, 2017: Journal of Applied Physiology
https://www.readbyqxmd.com/read/28910586/global-and-regional-cardiac-function-in-lifelong-endurance-athletes-with-and-without-myocardial-fibrosis
#9
Thijs M H Eijsvogels, David L Oxborough, Rory O'Hanlon, Sanjay Sharma, Sanjay Prasad, Greg Whyte, Keith P George, Mathew G Wilson
The aim of the present study was to compare cardiac structure as well as global and regional cardiac function in athletes with and without myocardial fibrosis (MF). Cardiac magnetic resonance imaging with late gadolinium enhancement was used to detect MF and global cardiac structure in nine lifelong veteran endurance athletes (58 ± 5 years, 43 ± 5 years of training). Transthoracic echocardiography using tissue-Doppler and myocardial strain imaging assessed global and regional (18 segments) longitudinal left ventricular function...
September 14, 2017: European Journal of Sport Science
https://www.readbyqxmd.com/read/28903708/united-and-divided-by-stress-how-stressors-differentially-influence-social-support-in-african-american-couples-over-time
#10
Frederick D Clavél, Carolyn E Cutrona, Daniel W Russell
The factors that allow people to be good support providers in relationships are not fully understood. We examined how support providers' stressful experiences (financial strain and racial discrimination) differentially influence their supportiveness, using longitudinal data from two samples of African American couples. Among couples that provided observational data ( N = 163 couples), providers who experienced high chronic financial strain behaved less supportively toward their partners, while those who experienced frequent racial discrimination behaved more supportively over a 2-year period...
July 2017: Personality & Social Psychology Bulletin
https://www.readbyqxmd.com/read/28902663/aldosterone-induces-left-ventricular-subclinical-systolic-dysfunction-a-strain-imaging-study
#11
Zheng-Wei Chen, Kuan-Chih Huang, Jen-Kuang Lee, Lung-Chun Lin, Ching-Way Chen, Yi-Yao Chang, Che-Wei Liao, Vin-Cent Wu, Chi-Shen Hung, Yen-Hung Lin
BACKGROUND: Primary aldosteronism is associated with a higher incidence of left ventricular (LV) hypertrophy and diastolic dysfunction than essential hypertension. However, systolic function via endocardial measurements is similar between patients with primary aldosteronism and essential hypertension. Speckle-tracking echocardiography is a sensitive tool which can detect subclinical impairments in systolic function. The aim of this study was to investigate aldosterone-induced subclinical impairments in systolic function...
September 11, 2017: Journal of Hypertension
https://www.readbyqxmd.com/read/28899951/lowering-interleukin-12-activity-improves-myocardial-and-vascular-function-compared-with-tumor-necrosis-factor-a-antagonism-or-cyclosporine-in-psoriasis
#12
Ignatios Ikonomidis, Evangelia Papadavid, George Makavos, Ioanna Andreadou, Maria Varoudi, Kostas Gravanis, Kostas Theodoropoulos, George Pavlidis, Helen Triantafyllidi, Paraskevi Moutsatsou, Christina Panagiotou, John Parissis, Efstathios Iliodromitis, John Lekakis, Dimitrios Rigopoulos
BACKGROUND: Interleukin (IL)-12 activity is involved in the pathogenesis of psoriasis and acute coronary syndromes. We investigated the effects of IL-12 inhibition on vascular and left ventricular (LV) function in psoriasis. METHODS AND RESULTS: One hundred fifty psoriasis patients were randomized to receive an anti-IL-12/23 (ustekinumab, n=50), anti-tumor necrosis factor-a (TNF-α; etanercept, n=50), or cyclosporine treatment (n=50). At baseline and 4 months post-treatment, we measured (1) LV global longitudinal strain, twisting, and percent difference between peak twisting and untwisting at mitral valve opening (%untwMVO) using speckle-tracking echocardiography, (2) coronary flow reserve, (3) pulse wave velocity and augmentation index, (4) circulating NT-proBNP (N-terminal pro-B-type natriuretic peptide), TNF-α, IL-6, IL-12, IL-17, malondialdehyde, and fetuin-a...
September 2017: Circulation. Cardiovascular Imaging
https://www.readbyqxmd.com/read/28899895/biomechanical-and-hemodynamic-measures-of-right-ventricular-diastolic-function-translating-tissue-biomechanics-to-clinical-relevance
#13
Sae Jang, Rebecca R Vanderpool, Reza Avazmohammadi, Eugene Lapshin, Timothy N Bachman, Michael Sacks, Marc A Simon
BACKGROUND: Right ventricular (RV) diastolic function has been associated with outcomes for patients with pulmonary hypertension; however, the relationship between biomechanics and hemodynamics in the right ventricle has not been studied. METHODS AND RESULTS: Rat models of RV pressure overload were obtained via pulmonary artery banding (PAB; control, n=7; PAB, n=5). At 3 weeks after banding, RV hemodynamics were measured using a conductance catheter. Biaxial mechanical properties of the RV free wall myocardium were obtained to extrapolate longitudinal and circumferential elastic modulus in low and high strain regions (E1 and E2, respectively)...
September 12, 2017: Journal of the American Heart Association
https://www.readbyqxmd.com/read/28899401/the-impact-of-preload-on-3-dimensional-deformation-parameters-principal-strain-twist-and-torsion
#14
Hyo-Suk Ahn, Yong-Kyun Kim, Ho Chul Song, Euy Jin Choi, Gee-Hee Kim, Jung Sun Cho, Sang-Hyun Ihm, Hee-Yeol Kim, Chan Seok Park, Ho-Joong Youn
BACKGROUND: Strain analysis is feasible using three-dimensional (3D) echocardiography. This approach provides various parameters based on speckle tracking analysis from one full-volume image of the left ventricle; however, evidence for its volume independence is still lacking. METHODS: Fifty-eight subjects who were examined by transthoracic echocardiography immediately before and after hemodialysis (HD) were enrolled. Real-time full-volume 3D echocardiographic images were acquired and analyzed using dedicated software...
September 12, 2017: Cardiovascular Ultrasound
https://www.readbyqxmd.com/read/28895191/early-assessment-of-the-left-ventricular-function-by-epirubicin-induced-cardiotoxicity-in-postoperative-breast-cancer-patients
#15
Runlan Luo, Hongyan Cui, Dongmei Huang, Guangsen Li
OBJECTIVE: Epirubicin (Epi) is a potent and effective drug for many malignant cancers with serious cardiotoxicity. Therefore, layer-specific two-dimensional speckle tracking echocardiography (2D-STE) was used to evaluate the longitudinal and circumferential systolic function of the left ventricular for the early detection of cardiotoxicity in this retrospective work. METHODS: Overall, 130 female patients with postoperative breast cancer who did not receive radiotherapy were classified into three groups: Group A (control group, n = 40) without any chemotherapy; Group B (n = 44) administered Epi at 180 ~ 240 mg/m(2) ; and Group C (n = 46) administered Epi at ≥360 mg/m(2) ...
September 12, 2017: Echocardiography
https://www.readbyqxmd.com/read/28894923/differences-in-myocardial-strain-between-pectus-excavatum-patients-and-healthy-subjects-assessed-by-cardiac-mri-a-pilot-study
#16
André Lollert, Tilman Emrich, Jakob Eichstädt, Christoph Kampmann, Tariq Abu-Tair, Salmai Turial, Christoph Düber, Karl-Friedrich Kreitner, Gundula Staatz
OBJECTIVES: To evaluate differences in myocardial strain between pectus excavatum (PE) patients and healthy subjects (HS) assessed by cardiac MRI using the feature-tracking algorithm. METHODS: Cardiac MRI was performed in 14 PE patients and 14 HS (9:5 male to female in each group; age 11-30 years) using a 3T scanner. Post-examination analysis included manual biventricular contouring with volumetry and ejection fraction measurement by two independent radiologists...
September 11, 2017: European Radiology
https://www.readbyqxmd.com/read/28893611/emerging-peak-on-the-phylogeographic-landscape-of-mycobacterium-tuberculosis-in-west-asia-definitely-smoke-likely-fire
#17
Igor Mokrousov, Egor Shitikov, Yuriy Skiba, Sergey Kolchenko, Ekaterina Chernyaeva, Anna Vyazovaya
To date, a major attention was justly given to the global lineages of Mycobacterium tuberculosis. Here, we demonstrated an importance of the minor ones, on an example of intriguing and underestimated NEW-1 family that belongs to Euro-American lineage (lineage 4). Analysis of the global WGS/NGS datasets (5715 strains) identified 2235 strains of Lineage 4 and 66 strains of sublineage L4.5. This latter is marked with RD122 genomic deletion and includes NEW-1 family. Phylogenomic analysis confirmed a separate position of the NEW-1 family that we tentatively designate L4...
September 8, 2017: Molecular Phylogenetics and Evolution
https://www.readbyqxmd.com/read/28889326/myocardial-contractile-patterns-predict-future-cardiac-events-in-sarcoidosis
#18
Jian Chen, Juan Lei, Ernest Scalzetti, Mary McGrath, David Feiglin, Robert Voelker, Jingfeng Wang, Michael C Iannuzzi, Kan Liu
The poor prognosis of cardiac sarcoidosis (CS) underscores the need for risk stratification. We evaluated 84 consecutive sarcoidosis patients who were referred for echocardiographic studies for cardiac symptoms or abnormal electrocardiograms. In 54 patients without previous diagnosis of CS or other known structural heart disease, 13 reached endpoints during (median) 24 months follow up. Significantly impaired peak systolic longitudinal strain in their original echocardiograms were identified in 13 of 17 left ventricular segments, clustering in the free wall, interventricular septum and apex...
September 9, 2017: International Journal of Cardiovascular Imaging
https://www.readbyqxmd.com/read/28875298/2d-longitudinal-lv-speckle-tracking-strain-pattern-in-breast-cancer-survivors-sports-activity-vs-exercise-as-prescription-model
#19
Giorgio Galanti, Gianni Pedrizzetti, Stefano Pedri, Laura Stefani
Prevention strategies are important to optimize and to manage heart care in breast cancer survivors. Regular physical activity at moderate intensity is normally proposed to maintain myocardial performance; however, no data is available about the different impact of different levels of physical exercise. 2D speckle tracking echocardiography (2DSTE) is an accepted method for early detection of myocardial dysfunction. The study aims to monitor the cardiac performances in breast cancer survivors by 2DSTE analysis to manage sports activity vs physical activity...
September 5, 2017: Internal and Emergency Medicine
https://www.readbyqxmd.com/read/28875228/myocardial-deformation-assessed-by-longitudinal-strain-chamber-specific-normative-data-for-cmr-feature-tracking-from-the-german-competence-network-for-congenital-heart-defects
#20
Quanliang Shang, Shivani Patel, Michael Steinmetz, Andreas Schuster, David A Danford, Philipp Beerbaum, Samir Sarikouch, Shelby Kutty
PURPOSE: Left ventricular two-dimensional global longitudinal strain (LS) is superior to ejection fraction (EF) as predictor of outcome. We provide reference data for atrial and ventricular global LS during childhood and adolescence by CMR feature tracking (FT). METHODS: We prospectively enrolled 115 healthy subjects (56 male, mean age 12.4 ± 4.1 years) at a single institution. CMR consisted of standard two-dimensional steady-state free-precession acquisitions...
September 5, 2017: European Radiology
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