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disability, frail

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https://www.readbyqxmd.com/read/28329858/cystatin-c-and-the-risk-of-frailty-and-mortality-in-older-men
#1
Allyson Hart, Terri L Blackwell, Misti L Paudel, Brent C Taylor, Eric S Orwoll, Peggy M Cawthon, Kristine E Ensrud
Background: This study examines the association between cystatin C (cysC) levels and risks of progression of frailty status or death in older men. Methods: Prospective study of 2,613 men without overt frailty aged 67 years and older enrolled in the MrOS ancillary sleep study. Baseline measurements included serum cysC, serum creatinine, and frailty status. Repeat frailty status, performed an average of 3.4 years later, was assessed as an ordinal outcome of robust, intermediate stage (prefrail), frail or dead...
November 9, 2016: Journals of Gerontology. Series A, Biological Sciences and Medical Sciences
https://www.readbyqxmd.com/read/28315394/physical-activity-and-dietary-habits-related-to-cardiovascular-risk-in-independent-community-living-older-women
#2
A B Fraile-Bermúdez, M Kortajarena, I Zarrazquin, A Irazusta, A Fernandez-Atutxa, F Ruiz-Litago, J J Yanguas, J Gil, J Irazusta
A side effect of increased life expectancy is a surge in sequelae of diseases and injuries, which in turn increase the duration of life with disability among the elderly. The aim of this study was to ascertain the physical activity and nutritional parameters that better predict cardiovascular risk in a cohort of older women. A cross-sectional study was designed including 65 women able to independently perform basic activities of daily life. Data collection included anthropometric measurement, blood pressure measurement, blood analytics, objectively measurement of physical activity, and dietary assessment...
March 14, 2017: Experimental Gerontology
https://www.readbyqxmd.com/read/28295847/effects-on-leisure-activities-and-social-participation-of-a-case-management-intervention-for-frail-older-people-living-at-home-a-randomised-controlled-trial
#3
Marianne Granbom, Jimmie Kristensson, Magnus Sandberg
Frailty causes disability and restrictions on older people's ability to engage in leisure activities and for social participation. The objective of this study was to evaluate the effects of a 1-year case management intervention for frail older people living at home in Sweden in terms of social participation and leisure activities. The study was a randomised controlled trial with repeated follow-ups. The sample (n = 153) was consecutively and randomly assigned to intervention (n = 80) or control groups (n = 73)...
March 12, 2017: Health & Social Care in the Community
https://www.readbyqxmd.com/read/28286988/exercise-and-nutritional-approaches-to-prevent-frail-bones-falls-and-fractures-an-update
#4
REVIEW
R M Daly
Osteoporosis (low bone strength) and sarcopenia (low muscle mass, strength and/or impaired function) often co-exist (hence the term 'sarco-osteoporosis') and have similar health consequences with regard to disability, falls, frailty and fractures. Exercise and adequate nutrition, particularly with regard to vitamin D, calcium and protein, are key lifestyle approaches that can simultaneously optimize bone, muscle and functional outcomes in older people, if they are individually tailored and appropriately prescribed in terms of the type and dose...
April 2017: Climacteric: the Journal of the International Menopause Society
https://www.readbyqxmd.com/read/28285816/survival-disabilities-in-activities-of-daily-living-and-physical-and-cognitive-functioning-among-the-oldest-old-in-china-a-cohort-study
#5
Yi Zeng, Qiushi Feng, Therese Hesketh, Kaare Christensen, James W Vaupel
BACKGROUND: The oldest-old (those aged ≥80 years) are the most rapidly growing age group globally, and are most in need of health care and assistance. We aimed to assess changes in mortality, disability in activities of daily living, and physical and cognitive functioning among oldest-old individuals between 1998 and 2008. METHODS: We used data from the Chinese Longitudinal Healthy Longevity Study. Three pairs of cohorts aged 80-89 years, 90-99 years, and 100-105 years (in total, 19 528 oldest-old participants) were examined; the two cohorts in each pair were born 10 years apart, with the same age at the time of the assessment in the 1998 and 2008 surveys...
March 9, 2017: Lancet
https://www.readbyqxmd.com/read/28276169/intergenerational-transfers-and-informal-care-for-disabled-elderly-persons-in-china-evidence-from-charls
#6
Xiaoting Liu, Bei Lu, Zhixin Feng
Aiming at 'ageing healthier and ageing better', a certain amount of high-quality informal care should be available for elderly persons with physical disability as formal care is barely accessible in China. The demographic transition and family structural changes have dramatically weakened traditional norms of filial piety and the structure of intergenerational transfers. This article employed nationwide representative data from the first wave (2011) of Chinese Health and Retirement Longitudinal Study (CHARLS) in order to identify the duration of informal care provision at home for frail elders (1122 in rural areas and 577 in urban areas, total 1699), measured in monthly hours, before estimating the associations between intergenerational transfers and the received time of informal care with Tobit Model analysis...
March 9, 2017: Health & Social Care in the Community
https://www.readbyqxmd.com/read/28243456/is-frailty-a-relevant-concept-in-sle
#7
Patricia P Katz, James Andrews, Jinoos Yazdany, Gabriela Schmajuk, Laura Trupin, Edward Yelin
OBJECTIVE: In geriatric populations, frailty is associated with poor health outcomes, including mortality. Frailty has not been examined in lupus, although components of the phenotype seem relevant. METHODS: Women with lupus (n=152) participated in research visits in 2008-2009. Frailty was assessed by Fried's frailty phenotype criteria: low weight/unintentional weight loss, slow gait (4-m walk using sex and height criteria), weakness (grip strength using gender and body mass index criteria), exhaustion (2 specific questions) and inactivity (from physical activity questionnaire)...
2017: Lupus Science & Medicine
https://www.readbyqxmd.com/read/28228654/low-ft3-a-possible-marker-of-frailty-in-the-elderly
#8
Aldo Bertoli, Alessia Valentini, Maria Assunta Cianfarani, Elena Gasbarra, Umberto Tarantino, Massimo Federici
INTRODUCTION: Frailty is associated with a functional decline of multiple physiological systems, of which they may be a cause or consequence. The objective of the study was to evaluate the prevalence of thyroid hormone modifications in elderly frail subjects and its relationship with frailty. STUDY POPULATION AND METHODS: An observational study was carried out at the University Hospital "Tor Vergata" in Rome among ambulatory and hospitalized patients. The study population consisted of 112 elderly subjects: 62 were hospitalized following hip fracture and 50 control subjects were outpatients...
2017: Clinical Interventions in Aging
https://www.readbyqxmd.com/read/28223787/comparing-the-predictive-accuracy-of-frailty-comorbidity-and-disability-for-mortality-a-1-year-follow-up-in-patients-hospitalized-in-geriatric-wards
#9
Martin Ritt, Julia Isabel Ritt, Cornel Christian Sieber, Karl-Günter Gaßmann
BACKGROUND: Studies evaluating and comparing the power of frailty, comorbidity, and disability instruments, together and in parallel, for predicting mortality are limited. OBJECTIVE: This study aimed to evaluate and compare the measures of frailty, comorbidity, and disability in predicting 1-year mortality in geriatric inpatients. DESIGN: Prospective cohort study. PATIENTS AND SETTING: A total of 307 inpatients aged ≥65 years in geriatric wards of a general hospital participated in the study...
2017: Clinical Interventions in Aging
https://www.readbyqxmd.com/read/28177146/precarity-in-late-life-rethinking-dementia-as-a-frailed-old-age
#10
Amanda Grenier, Liz Lloyd, Chris Phillipson
Approaches to ageing that are organised around productivity, success, and active late life have contributed to views of dementia as an unsuccessful, failed or 'frailed' old age. Operating through dominant frameworks, socio-cultural constructs and organisational practices, the 'frailties' of the body and mind are often used to mark the boundaries of health and illness in late life, and shape responses accordingly. Our concern is that both the taken for granted and the 'imagined' can further marginalise persons who occupy the locations of dementia and disablement...
February 2017: Sociology of Health & Illness
https://www.readbyqxmd.com/read/28170120/physical-function-grip-strength-and-frailty-in-people-living-with-hiv-in-sub-saharan-africa-systematic-review
#11
REVIEW
Charlotte Bernard, François Dabis, Nathalie de Rekeneire
OBJECTIVE: To present the current knowledge on physical function, grip strength and frailty in HIV-infected patients living in sub-Saharan Africa, where the phenomenon is largely underestimated. METHODS: A systematic search was conducted on MEDLINE, Scopus and African Index Medicus. We reviewed articles on sub-Saharan African people living with HIV (PLHIV) >18 years old, published until November 2016. RESULTS: Of 537 articles, 12 were conducted in six African countries and included in this review...
February 7, 2017: Tropical Medicine & International Health: TM & IH
https://www.readbyqxmd.com/read/28162927/the-standardization-of-frailty-phenotype-criteria-improves-its-predictive-ability-the-toledo-study-for-healthy-aging
#12
Cristina Alonso Bouzón, Jose Antonio Carnicero, Jimmy Gonzáles Turín, Francisco J García-García, Andrés Esteban, Leocadio Rodríguez-Mañas
INTRODUCTION: Several studies have assessed the performance of the original frailty phenotype criteria (FPC) and the standardized version according to the characteristics of the population. No studies exist, however, evaluating the impact of this standardization on its predictive ability. OBJECTIVE: To compare how the original FPC and the standardized-frailty phenotype criteria (S-FPC) estimate the prevalence of frailty and their ability to predict mortality, hospitalization, incident disability, and falls...
February 2, 2017: Journal of the American Medical Directors Association
https://www.readbyqxmd.com/read/28155181/nutrition-frailty-and-sarcopenia
#13
Alfonso J Cruz-Jentoft, Eva Kiesswetter, Michael Drey, Cornel C Sieber
Frailty and sarcopenia are important concepts in the quest to prevent physical dependence, as geriatrics are shifting towards identifications of early stages of disability. Definitions of both sarcopenia and frailty are still developing, and both concepts clearly overlap in their physical aspects. Malnutrition (both undernutrition and obesity) plays a key role in the pathogenesis of frailty and sarcopenia. The quality of the diet along the lifespan has a close relation with the incidence of both entities, and nutritional interventions may be able to reduce the incidence or revert either of them...
February 2017: Aging Clinical and Experimental Research
https://www.readbyqxmd.com/read/28144914/the-sarcopenia-and-physical-frailty-in-older-people-multi-component-treatment-strategies-sprintt-randomized-controlled-trial-design-and-methods
#14
Francesco Landi, Matteo Cesari, Riccardo Calvani, Antonio Cherubini, Mauro Di Bari, Raphael Bejuit, Jerome Mshid, Sandrine Andrieu, Alan J Sinclair, Cornel C Sieber, Bruno Vellas, Eva Topinkova, Timo Strandberg, Leocadio Rodriguez-Manas, Fabrizia Lattanzio, Marco Pahor, Ronenn Roubenoff, Alfonso J Cruz-Jentoft, Roberto Bernabei, Emanuele Marzetti
The sustainability of health and social care systems is threatened by a growing population of older persons with heterogeneous needs related to multimorbidity, frailty, and increased risk of functional impairment. Since disability is difficult to reverse in old age and is extremely burdensome for individuals and society, novel strategies should be devised to preserve adequate levels of function and independence in late life. The development of mobility disability, an early event in the disablement process, precedes and predicts more severe forms of inability...
January 31, 2017: Aging Clinical and Experimental Research
https://www.readbyqxmd.com/read/28143618/the-psychometric-properties-of-the-chinese-version-reintegration-to-normal-living-index-c-rnli-for-identifying-participation-restriction-among-community-dwelling-frail-older-people
#15
Justina Yat-Wa Liu, Ka Wai Ma
BACKGROUND: The Reintegration to Normal Living Index (RNLI) was developed to measure reintegration to normal living after major traumas/illnesses. Its psychometric properties remain unknown when used to measure participation restriction under the World Health Organization's International Classification of Functioning, Disability, and Health (WHO-ICF) framework. This study examines the psychometric properties of the Chinese version-RNLI to measure WHO-ICF participation restriction among community-dwelling pre-frail and frail older people...
January 31, 2017: BMC Geriatrics
https://www.readbyqxmd.com/read/28143597/the-severity-and-associated-factors-of-participation-restriction-among-community-dwelling-frail-older-people-an-application-of-the-international-classification-of-functioning-disability-and-health-who-icf
#16
Justina Yat Wa Liu
BACKGROUND: The International Classification of Functioning, Disability, and Health (WHO-ICF) describes participation restriction as one aspect of disability. Participation restriction refers to health problems that can hinder people's involvement in different life events. It is rational to believe that the prevalence of participation restriction increases among a frail population. However, information about the level of participation restriction among older people, particularly the pre-frail or frail, remains scant...
January 31, 2017: BMC Geriatrics
https://www.readbyqxmd.com/read/28126138/general-practitioners-clinical-impression-in-the-screening-for-frailty-data-from-the-fap-study-pilot
#17
Bertrand Fougère, Marie-Josée Sirois, Pierre-Hugues Carmichael, Brice-Lionel Batomen-Kuimi, Bruno Chicoulaa, Emile Escourrou, Fati Nourhashémi, Stéphane Oustric, Bruno Vellas
BACKGROUND: The progression of frailty is marked by an increased risk of adverse health outcomes in the elderly including falls, physical and/or cognitive disability, hospitalizations, and mortality. In primary care, the general practitioner's (GP's) clinical impression about their elderly patients' frailty state seems to be a key point in identifying frail individuals in their clinical practice. The aim of this article is to examine if GPs' clinical impressions regarding frailty concurs with objective measures of the gold standard frailty phenotype as described by Fried in community-dwelling older persons...
February 1, 2017: Journal of the American Medical Directors Association
https://www.readbyqxmd.com/read/28126135/prevention-of-functional-decline-by-reframing-the-role-of-nursing-homes
#18
Clarisse Laffon de Mazières, John E Morley, Cari Levy, Fabien Agenes, Mario Barbagallo, Matteo Cesari, Philipe De Souto Barreto, Lorenzo Maria Donini, Jaime Fitten, Alain Franco, Mikel Izquierdo, Rosalie A Kane, Finbarr C Martin, Graziano Onder, Joseph Ouslander, Kaisu Pitkälä, Debra Saliba, Alan Sinclair, Leocadio Rodriguez Manas, Bruno Vellas, Yves Rolland
Institutionalization is generally a consequence of functional decline driven by physical limitations, cognitive impairments, and/or loss of social supports. At this stage, intervention to reverse functional losses is often too late. To be more effective, geriatric medicine must evolve to intervene at an earlier stage of the disability process. Could nursing homes (NHs) transform from settings in which many residents dwell to settings in which the NH residents and those living in neighboring communities benefit from staff expertise to enhance quality of life and maintain or slow functional decline? A task force of clinical researchers met in Toulouse on December 2, 2015, to address some of these challenges: how to prevent or slow functional decline and disabilities for NH residents and how NHs may promote the prevention of functional decline in community-dwelling frail elderly...
February 1, 2017: Journal of the American Medical Directors Association
https://www.readbyqxmd.com/read/28112495/design-of-the-mobility-and-independent-living-in-elders-study-an-older-adult-cohort-in-rural-india
#19
Tushar Singh, Pawan K Sharma, Guru Rajesh Jammy, Jane A Cauley, Clareann H Bunker, P S Reddy, Anne B Newman
AIM: The Mobility and Independent Living in Elders Study (MILES) was established in 2012 to estimate the prevalence, incidence, and risk factors for disability and age-related disease in rural older Indians. Here we describe the main goals of MILES, the essential elements of its design and examinations, and the initial findings from the baseline visit. METHODS: A random sample of 562 men and women aged ≥60 years was enrolled from the Medchal region in Telangana State...
January 2017: Geriatrics & Gerontology International
https://www.readbyqxmd.com/read/28089304/management-of-prostate-cancer-in-elderly-patients-recommendations-of-a-task-force-of-the-international-society-of-geriatric-oncology
#20
REVIEW
Jean-Pierre Droz, Gilles Albrand, Silke Gillessen, Simon Hughes, Nicolas Mottet, Stéphane Oudard, Heather Payne, Martine Puts, Gilbert Zulian, Lodovico Balducci, Matti Aapro
CONTEXT: Prostate cancer is the most frequent male cancer. Since the median age of diagnosis is 66 yr, many patients require both geriatric and urologic evaluation if treatment is to be tailored to individual circumstances including comorbidities and frailty. OBJECTIVE: To update the 2014 International Society of Geriatric Oncology (SIOG) guidelines on prostate cancer in men aged >70 yr. The update includes new material on health status evaluation and the treatment of localised, advanced, and castrate-resistant disease...
January 11, 2017: European Urology
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