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https://www.readbyqxmd.com/read/28239875/american-cutaneous-leishmaniasis-in-situ-immune-response-of-patients-with-recent-and-late-lesions
#1
Aparecida Helena Souza Gomes, Roosecelis Brasil Martines, Cristina Takami Kanamura, Maria Lourdes Peris Barbo, Silvia D'Andretta Iglezias, José Angelo Lauletta Lindoso, Vera Lucia Pereira-Chioccola
TNF-α, IFN-γ, IL-10, IL-17, CD68, and CD57 were evaluated in biopsies of patients with American cutaneous leishmaniasis living in Sorocaba, Brazil. The analyses were performed considering the time of lesions from 23 patients with recent lesions (Group I) and 19 patients with late lesions (Group II). All patients were infected with Leishmania (Viannia) braziliensis. Immunostaining cells for CD68, CD57, TNF- α, IFN-γ, IL-10, and IL-17 were performed by immunohistochemistry. Except for CD68 and IL-17, the distribution of in situ for CD57, IL-10, TNF-α and IFN-γ showed that patients with recent lesions expressed higher levels than those with late lesions...
February 26, 2017: Parasite Immunology
https://www.readbyqxmd.com/read/28228848/brazilian-dietary-patterns-and-the-dietary-approaches-to-stop-hypertension-dash-diet-relationship-with-metabolic-syndrome-and-newly-diagnosed-diabetes-in-the-elsa-brasil-study
#2
Michele Drehmer, Andrew O Odegaard, Maria Inês Schmidt, Bruce B Duncan, Letícia de Oliveira Cardoso, Sheila M Alvim Matos, Maria Del Carmen B Molina, Sandhi M Barreto, Mark A Pereira
BACKGROUND: Studies evaluating dietary patterns, including the DASH diet, and their relationship with the metabolic syndrome and diabetes may help to understand the role of dairy products (low fat or full fat) in these conditions. Our aim is to identify dietary patterns in Brazilian adults and compare them with the (DASH) diet quality score in terms of their associations with metabolic syndrome and newly diagnosed diabetes in the Brazilian Longitudinal Study of Adult Health-the ELSA-Brasil study...
2017: Diabetology & Metabolic Syndrome
https://www.readbyqxmd.com/read/28227728/comparison-between-users-of-a-new-methodology-for-heart-sound-auscultation
#3
Ana Castro, Pedro Gomes, Sandra S Mattos, Miguel T Coimbra, Ana Castro, Pedro Gomes, Sandra S Mattos, Miguel T Coimbra, Ana Castro, Sandra S Mattos, Pedro Gomes, Miguel Y Coimbra
Auscultation is a routine exam and the first line of screening in heart pathologies. The objective of this study was to assess if using a new data collection system, the DigiScope Collector, with a guided and automatic annotation of heart auscultation, different levels of expertise/experience users could collect similar digital auscultations. Data were collected within the Heart Caravan Initiative (Paraíba, Brasil). Patients were divided into two study groups: Group 1 evaluated by a third year medical student (User 1), and an experienced nurse (User 2); Group 2 evaluated by User 2 and an Information Technology professional (User 3)...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28226055/functional-health-literacy-and-knowledge-of-renal-patients-on-pre-dialytic-treatment
#4
Katarinne Lima Moraes, Virginia Visconde Brasil, Gabriela Ferreira de Oliveira, Jacqueline Andréia Bernardes Leão Cordeiro, Antonio Márcio Teodoro Cordeiro Silva, Rafaela Peres Boaventura, Denize Bouttelet Munari, Mônica Ribeiro Canhestro
Objective: to analyze the functional health literacy (FHL), i.e., understanding and knowledge about chronic renal disease of 60 patients in pre-dialytic treatment. Method: this is a cross-sectional study. FHL was measured by B-TOFHLA; and the knowledge, by questionnaire. Pearson correlation and Chi-square tests were carried out as well as linear regression models. Results: all respondents presented inadequate FHL, and most showed insufficient knowledge about the disease and treatment...
January 2017: Revista Brasileira de Enfermagem
https://www.readbyqxmd.com/read/28226026/diabetes-mellitus-and-sensorineural-hearing-loss-is-there-an-association-baseline-of-the-brazilian-longitudinal-study-of-adult-health-elsa-brasil
#5
Alessandra G Samelli, Itamar S Santos, Renata R Moreira, Camila M Rabelo, Laurie P Rolim, Isabela J Bensenõr, Paulo A Lotufo
OBJECTIVES: Although several studies have investigated the effects of diabetes on hearing loss, the relationship between these two conditions remains unclear. Some studies have suggested that diabetes may cause sensorineural hearing loss, whereas others have failed to find an association. The biggest challenge in investigating the association between diabetes and hearing loss is the presence of confounding variables and the complexity of the auditory system. Our study investigated the association between diabetes and sensorineural hearing loss...
January 1, 2017: Clinics
https://www.readbyqxmd.com/read/28225901/tuberculosis-associated-factors-caused-by-mycobacterium-tuberculosis-of-the-rdrio-genotype
#6
Eloise Brasil Moraes, Letícia Slompo, Amanda Juliane Finardi, Heloisa Paro Pedro da Silveira, Luciana Ruiz, Harrison Magdinier Gomes, Virginia Bodelão Richini, Philip Suffys, Carlos Magno Castelo Branco Fortaleza, Ricardo Cavalcanti, Ida Maria Foschiani Dias Baptista
BACKGROUND: Tuberculosis (TB) continues to be a disease that affects many countries around the world, including Brazil. Recently, a subtype of Latin American-Mediterranean family strain was identified and characterised by RDRio. The strain has been associated with different characteristics of the disease. OBJECTIVES: In the present study we investigated the association of epidemiological, clinical, radiological and bacteriological variables with pulmonary tuberculosis caused by RDRioMycobacterium tuberculosis strain in large regions of São Paulo...
March 2017: Memórias do Instituto Oswaldo Cruz
https://www.readbyqxmd.com/read/28225895/tuberculosis-associated-factors-caused-by-mycobacterium-tuberculosis-of-the-rdrio-genotype
#7
Eloise Brasil Moraes, Letícia Slompo, Amanda Juliane Finardi, Heloisa Paro Pedro da Silveira, Luciana Ruiz, Harrison Magdinier Gomes, Virginia Bodelão Richini, Philip Suffys, Carlos Magno Castelo Branco Fortaleza, Ricardo Cavalcanti, Ida Maria Foschiani Dias Baptista
BACKGROUND: Tuberculosis (TB) continues to be a disease that affects many countries around the world, including Brazil. Recently, a subtype of Latin American-Mediterranean family strain was identified and characterised by RDRio. The strain has been associated with different characteristics of the disease. OBJECTIVES: In the present study we investigated the association of epidemiological, clinical, radiological and bacteriological variables with pulmonary tuberculosis caused by RDRioMycobacterium tuberculosis strain in large regions of São Paulo...
February 16, 2017: Memórias do Instituto Oswaldo Cruz
https://www.readbyqxmd.com/read/28218662/microrna-expression-profile-identifies-high-grade-non-muscle-invasive-bladder-tumors-at-elevated-risk-to-progress-to-an-invasive-phenotype
#8
Sara M Lenherr, Sheaumei Tsai, Brasil Silva Neto, Travis B Sullivan, Cara B Cimmino, Tanya Logvinenko, Jason Gee, Wei Huang, John A Libertino, Ian C Summerhayes, Kimberly M Rieger-Christ
The objective of this study was to identify a panel of microRNAs (miRNAs) differentially expressed in high-grade non-muscle invasive (NMI; TaG3-T1G3) urothelial carcinoma that progress to muscle-invasive disease compared to those that remain non-muscle invasive, whether recurrence happens or not. Eighty-nine high-grade NMI urothelial carcinoma lesions were identified and total RNA was extracted from paraffin-embedded tissue. Patients were categorized as either having a non-muscle invasive lesion with no evidence of progression over a 3-year period or as having a similar lesion showing progression to muscle invasion over the same period...
February 17, 2017: Genes
https://www.readbyqxmd.com/read/28212935/dissecting-biochemical-peculiarities-of-the-atpase-activity-of-tcsub2-a-component-of-the-mrna-export-pathway-in-trypanosoma-cruzi
#9
Ize de Aguiar Bittencourt, Mariana Serpeloni, Priscila Mazzochi Hiraiwa, Tatiana de Arruda Campos Brasil de Souza, Andréa Rodrigues Ávila
The RNA helicase DEAD-box protein Sub2 (yeast)/UAP56 (mammals) is conserved across eukaryotes and is essential for mRNA export in trypanosomes. Despite the high conservation of Sub2 in lower eukaryotes such as Trypanosoma cruzi, the low conservation of other mRNA export factors raises questions regarding whether the mode of action of TcSub2 is similar to that of orthologs from other eukaryotes. Mutation of the conserved K87 residue of TcSub2 abolishes ATPase activity, showing that its ATPase domain is functional...
February 14, 2017: International Journal of Biological Macromolecules
https://www.readbyqxmd.com/read/28202059/cardiosphere-derived-cells-do-not-improve-cardiac-function-in-rats-with-cardiac-failure
#10
Taís Hanae Kasai-Brunswick, Andréa Rodrigues da Costa, Raiana Andrade Quintanilha Barbosa, Bruna Farjun, Fernanda Cristina Paccola Mesquita, Danúbia Silva Dos Santos, Isalira Peroba Ramos, Grazielle Suhett, Guilherme Visconde Brasil, Sandro Torrentes da Cunha, José Oscar R Brito, Juliana do Amaral Passipieri, Adriana Bastos Carvalho, Antonio Carlos Campos de Carvalho
BACKGROUND: Heart failure represents an important public health issue due to its high costs and growing incidence worldwide. Evidence showing the regenerative potential of postmitotic heart tissue has suggested the existence of endogenous cardiac stem cells in adult hearts. Cardiosphere-derived cells (CDC) constitute a candidate pool of such cardiac stem cells. Previous studies using acute myocardial infarction (MI) models in rodents demonstrated an improvement in cardiac function after cell therapy with CDC...
February 15, 2017: Stem Cell Research & Therapy
https://www.readbyqxmd.com/read/28198963/validation-of-the-comply-with-post-exposure-management-among-health-care-workers-instrument-for-brazil
#11
Adriane Corrêa Jansen, Maria Helena Palucci Marziale, Cláudia Benedita Dos Santos, Rosana Aparecida Spadotti Dantas, Danielle Maria de Souza Serio Dos Santos
OBJECTIVE: To validate the Comply with post-exposure management among healthcare workersinstrument for Nursing in Brazil. METHOD: A methodological study carried out with 137 nursing professionals exposed to biological material. The existence of floor and ceiling effects was analyzed, evaluating reliability by the internal consistency of the items and test-retest reproducibility. The construct validity was analyzed by the multitrait-multi method analysis. RESULTS: Ceiling effects were found in two subscales...
November 2016: Revista da Escola de Enfermagem da U S P
https://www.readbyqxmd.com/read/28198958/factors-associated-with-glycemic-control-in-people-with-diabetes-at-the-family-health-strategy-in-pernambuco
#12
Rodrigo Fonseca Lima, Annick Fontbonne, Eduardo Maia Freese de Carvalho, Ulisses Ramos Montarroyos, Maria Nelly Sobreira de Carvalho Barreto, Eduarda Ângela Pessoa Cesse
OBJECTIVE: Identifying factors associated with glycemic control in people with type 2 Diabetes Mellitus (DM) registered in the Family Health Strategy (FHS) in Pernambuco, Brazil. METHOD: Associations between glycemic control (glycosylated hemoglobin A lower or equal to 7%) presented by people with DM and variables related to sociodemographic conditions, lifestyle, characteristics of diabetes, treatment and follow-up of patients by health services were investigated by multiple regression...
November 2016: Revista da Escola de Enfermagem da U S P
https://www.readbyqxmd.com/read/28192127/long-term-treatment-with-nandrolone-decanoate-impairs-mesenteric-vascular-relaxation-in-both-sedentary-and-exercised-female-rats
#13
Izabela F Caliman, Cristian S Bernabe, Antônio F de Melo, Girlândia A Brasil, Andrews M do Nascimento, Ewelyne M de Lima, Suely G Figueiredo, Tadeu U de Andrade, Nazaré S Bissoli
Nandrolone Decanoate (ND) is an Anabolic Androgenic Steroid (AAS) that under abusive regimen can lead to multiple physiological adverse effects. Studies of AAS-mediated cardiovascular (CV) alterations were mostly taken from male subjects, even though women are also susceptible to the effects of AAS and gender-specific differences in susceptibility to vascular diseases exist. Here we investigate ND-induced vascular reactivity alterations in both sedentary and exercised female rats and whether these alterations depend on endothelium-derived factors...
February 10, 2017: Steroids
https://www.readbyqxmd.com/read/28191788/full-thickness-skin-mesh-graft-vaginoplasty-a-skin-sparing-technique
#14
Guilherme Lang Motta, Patric Machado Tavares, Gabriel Veber Moisés Silva, Milton Berger, Brasil Silva Neto, Tiago Elias Rosito
INTRODUCTION: The ideal vaginoplasty method should promote good cosmetic and functional results with low morbidity. We describe a new technique for congenital vaginal agenesis using a full-thickness perforated skin graft. MATERIALS AND METHODS: We report an 18 year old patient with vaginal agenesis (Morris syndrome) that undergone a modified version of McIndoe vaginoplasty. Patient is set in a low lithotomy position and lateral traction sutures are placed in labia and a 16Fr urethral catheter inserted...
January 27, 2017: International Braz J Urol: Official Journal of the Brazilian Society of Urology
https://www.readbyqxmd.com/read/28187764/new-potential-plasmodium-brasilianum-hosts-tamarin-and-marmoset-monkeys-family-callitrichidae
#15
Denise A M Alvarenga, Anielle Pina-Costa, Cesare Bianco, Silvia B Moreira, Patricia Brasil, Alcides Pissinatti, Claudio T Daniel-Ribeiro, Cristiana F A Brito
BACKGROUND: Non-human primates (NHPs) as a source for Plasmodium infections in humans are a challenge for malaria elimination. In Brazil, two species of Plasmodium have been described infecting NHPs, Plasmodium brasilianum and Plasmodium simium. Both species are infective to man. Plasmodium brasilianum resembles morphologically, genetically and immunologically the human quartan Plasmodium malariae. Plasmodium brasilianum naturally infects species of non-human primates from all New World monkey families from a large geographic area...
February 10, 2017: Malaria Journal
https://www.readbyqxmd.com/read/28177056/social-representations-of-the-health-care-of-the-mby%C3%A3-guarani-indigenous-population-by-health-workers
#16
Mirian Benites Falkenberg, Helena Eri Shimizu, Ximena Pamela Díaz Bermudez
Objective: to analyze the social representations of health care of the Mbyá-Guarani ethnic group by multidisciplinary teams from the Special Indigenous Health District in the south coast of Rio Grande do Sul state (Distrito Sanitário Especial Indígena Litoral Sul do Rio Grande do Sul), Brazil. Method: a qualitative method based on the theory of social representations was used. Data were collected via semi-structured interviews with 20 health workers and by participant observation...
February 6, 2017: Revista Latino-americana de Enfermagem
https://www.readbyqxmd.com/read/28177039/nematodes-of-astyanax-fasciatus-actinopterygii-characidae-and-their-parasitic-indices-in-the-s%C3%A3-o-francisco-river-brazil
#17
Flavia Guerra Vieira-Menezes, Danielle Priscilla Correia Costa, Marilia Carvalho Brasil-Sato
The endoparasite fauna of Astyanax fasciatus from the upper São Francisco river was investigated and ecological parameters and morphological and morphometric data on the parasites are presented. A total of 74 specimens of banded astyanax were collected downstream from the Três Marias dam, municipality of Três Marias, Minas Gerais (18°12'32"S, 45°15'41"W) in January 2011 and January 2012. Eleven taxa of Nematoda were found: Contracaecum sp.; Hysterothylacium sp.; Goezia sp.; Brevimulticaecum sp.; Procamallanus sp...
February 6, 2017: Revista Brasileira de Parasitologia Veterinária, Brazilian Journal of Veterinary Parasitology
https://www.readbyqxmd.com/read/28169041/treatment-of-postmenopausal-osteoporosis-a-literature-based-algorithm-for-use-in-the-public-health-care-system
#18
Ellen Luz Pereira Caires, Mailze Campos Bezerra, Ana Flávia Torquato de Araújo Junqueira, Sheila Márcia de Araújo Fontenele, Silvana Cristina de Albuquerque Andrade, Catarina Brasil d'Alva
Bisphosphonates are considered first-line agents in the treatment of postmenopausal osteoporosis based on extensive experience of use, safety, and proven efficacy in reducing vertebral, non-vertebral and femur fractures. However, post-marketing reports based on the treatment of millions of patients/year over lengthy periods of time have revealed the occurrence of initially unexpected adverse effects, such as osteonecrosis of the jaw and atypical femoral fracture, leading to the restriction of treatment duration with bisphosphonates by global regulatory agencies...
December 27, 2016: Revista Brasileira de Reumatologia
https://www.readbyqxmd.com/read/28164227/time-from-smoking-cessation-and-inflammatory-markers-new-evidence-from-a-cross-sectional-analysis-of-elsa-brasil
#19
Flávia Soares Peres, Sandhi Maria Barreto, Lidyane do Valle Camelo, Antonio Luiz P Ribeiro, Pedro Guatimosim Vidigal, Bruce Bartholow Duncan, Luana Giatti
No abstract text is available yet for this article.
February 6, 2017: Nicotine & Tobacco Research: Official Journal of the Society for Research on Nicotine and Tobacco
https://www.readbyqxmd.com/read/28163281/job-strain-and-binge-eating-among-brazilian-workers-participating-in-the-elsa-brasil-study-does-bmi-matter
#20
Ana Paula Bruno Pena Gralle, Arlinda Barbosa Moreno, Leidjaira Lopes Juvanhol, Maria de Jesus Mendes da Fonseca, Enirtes Caetano Prates Melo, Maria Angélica Antunes Nunes, Susanna Toivanen, Rosane Härter Griep
OBJECTIVE: To assess the association between job strain and binge eating as well as the effect-modifying influence of body mass index (BMI) on this association. METHODS: A total of 11,951 active civil servants from the multicenter Brazilian Longitudinal Study of Adult Health (ELSA-Brasil) was included in this cross-sectional analysis. Job strain was assessed using the Demand-Control-Support Questionnaire. Binge eating was defined as eating a large amount of food with a sense of lack of control over what and how much is eaten in less than 2 hours at least twice a week...
February 4, 2017: Journal of Occupational Health
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