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https://www.readbyqxmd.com/read/29149021/using-gamma-and-quantile-regressions-to-explore-the-association-between-job-strain-and-adiposity-in-the-elsa-brasil-study-does-gender-matter
#1
Maria de Jesus Mendes da Fonseca, Leidjaira Lopes Juvanhol, Lúcia Rotenberg, Aline Araújo Nobre, Rosane Härter Griep, Márcia Guimarães de Mello Alves, Letícia de Oliveira Cardoso, Luana Giatti, Maria Angélica Nunes, Estela M L Aquino, Dóra Chor
This paper explores the association between job strain and adiposity, using two statistical analysis approaches and considering the role of gender. The research evaluated 11,960 active baseline participants (2008-2010) in the ELSA-Brasil study. Job strain was evaluated through a demand-control questionnaire, while body mass index (BMI) and waist circumference (WC) were evaluated in continuous form. The associations were estimated using gamma regression models with an identity link function. Quantile regression models were also estimated from the final set of co-variables established by gamma regression...
November 17, 2017: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/29146548/first-molecular-characterisation-of-a-brazilian-burkholderia-mallei-strain-isolated-from-a-mule-in-2016
#2
K Laroucau, V Lucia de Assis Santana, G Girault, B Martin, P P Miranda da Silveira, M Brasil Machado, M Joseph, R Wernery, U Wernery, S Zientara, N Madani
We present the first molecular characterisation based on MLVA and SNP analysis of a strain of Burkholderia mallei isolated from a mule found dead in Brazil in 2016.
November 13, 2017: Infection, Genetics and Evolution
https://www.readbyqxmd.com/read/29146481/central-obesity-is-the-key-component-in-the-association-of-metabolic-syndrome-with-left-ventricular-global-longitudinal-strain-impairment
#3
Wilson Cañon-Montañez, Angela B S Santos, Lisandra A Nunes, Julio C G Pires, Claudia M V Freire, Antonio L P Ribeiro, José G Mill, Marina Bessel, Bruce B Duncan, Maria Inês Schmidt, Murilo Foppa
INTRODUCTION AND OBJECTIVES: Subclinical systolic dysfunction is one of the proposed mechanisms for increased cardiovascular risk associated with metabolic syndrome (MS). This study investigated the association between MS and impaired left ventricular global longitudinal strain (GLS) and the role of each MS criteria in this association. METHODS: We analyzed a random sample of the Brazilian Longitudinal Study of Adult Health (ELSA-Brasil) after excluding participants with prevalent heart disease...
November 13, 2017: Revista Española de Cardiología
https://www.readbyqxmd.com/read/29145452/behavioral-climatic-and-environmental-risk-factors-for-zika-and-chikungunya-virus-infections-in-rio-de-janeiro-brazil-2015-16
#4
Trevon L Fuller, Guilherme Calvet, Camila Genaro Estevam, Jussara Rafael Angelo, Gbenga J Abiodun, Umme-Aiman Halai, Bianca De Santis, Patricia Carvalho Sequeira, Eliane Machado Araujo, Simone Alves Sampaio, Marco Cesar Lima de Mendonça, Allison Fabri, Rita Maria Ribeiro, Ryan Harrigan, Thomas B Smith, Claudia Raja Gabaglia, Patrícia Brasil, Ana Maria Bispo de Filippis, Karin Nielsen-Saines
The burden of arboviruses in the Americas is high and may result in long-term sequelae with infants disabled by Zika virus infection (ZIKV) and arthritis caused by infection with Chikungunya virus (CHIKV). We aimed to identify environmental drivers of arbovirus epidemics to predict where the next epidemics will occur and prioritize municipalities for vector control and eventual vaccination. We screened sera and urine samples (n = 10,459) from residents of 48 municipalities in the state of Rio de Janeiro for CHIKV, dengue virus (DENV), and ZIKV by molecular PCR diagnostics...
2017: PloS One
https://www.readbyqxmd.com/read/29138749/auris-system-providing-vibrotactile-feedback-for-hearing-impaired-population
#5
Felipe Alves Araujo, Fabricio Lima Brasil, Allison Candido Lima Santos, Luzenildo de Sousa Batista Junior, Savio Pereira Fonseca Dutra, Carlos Eduardo Coelho Freire Batista
Deafness, an issue that affects millions of people around the globe, is manifested in different intensities and related to many causes. This impairment negatively affects different aspects of the social life of the deaf people, and music-centered situations (concerts, religious events, etc.) are obviously not inviting for them. The Auris System was conceived to provide the musical experimentation for people who have some type of hearing loss. This system is able to extract musical information from audio and create a representation for music pieces using different stimuli, a new media format to be interpreted by other senses than the hearing...
2017: BioMed Research International
https://www.readbyqxmd.com/read/29121794/what-factors-explain-bicycling-and-walking-for-commuting-by-elsa-brasil-participants
#6
Sheila Maria Alvim de Matos, Francisco José Gondim Pitanga, Maria da Conceição C Almeida, Ciro Oliveira Queiroz, Clarice Alves Dos Santos, Rogerio Tosta de Almeida, Ianne Tayrine Martins da Silva, Rosane Harter Griep, Leila Denise Alves Ferreira Amorim, Ana Luísa Patrão, Estela M L Aquino
PURPOSE: To analyze the factors associated with commuting by bicycling and walking in adult participants from ELSA-Brasil (Longitudinal Study of Adult Health). DESIGN: Cross-sectional. SETTING: Six teaching/research institutions throughout Brazil. PARTICIPANTS: A total of 15 105 civil servants. MEASURES: Commuting by bicycling and walking was analyzed using the long-form International Physical Activity Questionnaire...
January 1, 2017: American Journal of Health Promotion: AJHP
https://www.readbyqxmd.com/read/29114168/a-new-species-of-pristimantis-from-eastern-brazilian-amazonia-anura-craugastoridae
#7
Elciomar Araújo De Oliveira, Luis Reginaldo Rodrigues, Igor Luis Kaefer, Karll Cavalcante Pinto, Emil José Hernández-Ruz
In this study a new species of Pristimantis (Anura: Craugastoridae) of the P. conspicillatus species group is described. Pristimantis latrosp. n. is known only from the municipalities of Altamira, Anapu, Brasil Novo, Medicilândia, Uruará and Aveiro (Flona Tapajós, right bank of Tapajós river), in Pará state, Brazil. Morphologically, the new species distinguishes from known congeners in the group mainly by the presence of dorsal tubercles and absence of discoidal folds, smooth belly skin, as well as the presence of supernumerary tubercles on hands...
2017: ZooKeys
https://www.readbyqxmd.com/read/29111104/carotid-femoral-pulse-wave-velocity-in-a-healthy-adult-sample-the-elsa-brasil-study
#8
Marcelo Perim Baldo, Roberto S Cunha, Maria Del Carmen B Molina, Dora Chór, Rosane H Griep, Bruce B Duncan, Maria Inês Schmidt, Antonio L P Ribeiro, Sandhi M Barreto, Paulo A Lotufo, Isabela M Bensenor, Alexandre C Pereira, José Geraldo Mill
BACKGROUND: Aging declines essential physiological functions, and the vascular system is strongly affected by artery stiffening. We intended to define the age- and sex-specific reference values for carotid-to-femoral pulse wave velocity (cf-PWV) in a sample free of major risk factors. METHODS AND RESULTS: The ELSA-Brasil study enrolled 15,105 participants aged 35-74years. The healthy sample was achieved by excluding diabetics, those over the optimal and normal blood pressure levels, body mass index ≤18...
October 22, 2017: International Journal of Cardiology
https://www.readbyqxmd.com/read/29103825/is-subcranial-le-fort-iii-plus-le-fort-i-osteotomy-stable
#9
Fernanda Brasil Daura Jorge Boos Lima, Eduardo Hochuli Vieira, Philipp Juergens, Sergio Monteiro Lima Junior
The purpose of this study was to test whether associated subcranial Le Fort III (sLF III) and Le Fort I (LF I) osteotomies are stable after large advancements of the middle third of the face and maxilla. The authors designed a retrospective study and enrolled a sample of consecutive patients with midface hypoplasia treated with associated sLF III and LF I osteotomies in this IRB-approved study between September 2013 and February 2015. To test whether the long-term stability was satisfactory, the authors compared cephalometric changes from immediately after surgery to 18 months after surgery taken from multi-slice computed tomography using two different third-party imaging software programs...
October 3, 2017: Journal of Cranio-maxillo-facial Surgery
https://www.readbyqxmd.com/read/29100829/prospective-and-randomized-evaluation-of-chronos-and-bio-oss-in-human-maxillary-sinuses-histomorphometric-and-immunohistochemical-assignment-for-runx-2-vascular-endothelial-growth-factor-and-osteocalcin
#10
João Paulo Bonardi, Rodrigo Dos Santos Pereira, Fernanda Brasil Jorge Daura Boos, Leonarod Perez Faverani, Geraldo Luiz Griza, Roberta Okamoto, Eduardo Hochuli-Vieira
PURPOSE: The aim of this study was to compare ChronOS (β-tricalcium phosphate), Bio-Oss, and their addition to an autogenous bone graft in a 1:1 ratio in human maxillary sinus bone augmentation. MATERIALS AND METHODS: Thirty maxillary sinuses were divided in 5 groups: group 1 included 6 maxillary sinuses grafted with autogenous bone graft alone; group 2 included 6 maxillary sinuses grafted with ChronOS; group 3 included 6 maxillary sinuses grafted with ChronOS and autogenous bone graft in a 1:1 ratio; group 4 included 6 maxillary sinuses grafted with Bio-Oss; and group 5 included 6 maxillary sinuses grafted with Bio-Oss and autogenous bone graft in a 1:1 ratio...
October 10, 2017: Journal of Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/29096222/thyrotropin-level-and-cognitive-performance-baseline-results-from-the-elsa-brasil-study
#11
Claudia Szlejf, Claudia K Suemoto, Itamar S Santos, Paulo A Lotufo, Maria de Fátima Haueisen Sander Diniz, Sandhi Maria Barreto, Isabela M Benseñor
BACKGROUND AND AIMS: The role of subtle thyroid alterations, such as subclinical thyroid disease and low/high serum thyrotropin (TSH) within the normal range, on cognitive decline is controversial. The aim of this study was to evaluate the association of serum TSH and subclinical thyroid dysfunction with performance on cognitive tests in a large sample of Brazilian middle-aged adults without overt thyroid disease. METHODS: In this cross-sectional analysis of the Brazilian Longitudinal Study of Adult Health, we excluded individuals aged 65 years and older, with overt thyroid dysfunction, prevalent stroke, in use of medications that affect thyroid function or that indicate neurologic diseases, and from Asian or indigenous ethnicity...
October 20, 2017: Psychoneuroendocrinology
https://www.readbyqxmd.com/read/29091155/cross-cultural-adaptation-and-validation-to-brazil-of-the-obesity-related-problems-scale
#12
Andreia Mara Brolezzi Brasil, Fábio Brasil, Angélica Aparecida Maurício, Regina Maria Vilela
OBJECTIVE: To validate a reliable version of the Obesity-related Problems Scale in Portuguese to use it in Brazil. METHODS: The Obesity-related Problems Scale was translated and transculturally adapted. Later it was simultaneously self-applied with a 12-item version of the World Health Organization Disability Assessment Schedule 2.0 (WHODAS 2.0), to 50 obese patients and 50 non-obese individuals, and applied again to half of them after 14 days. RESULTS: The Obesity-related Problems scale was able to differentiate obese from non-obese individuals with higher accuracy than WHODAS 2...
July 2017: Einstein
https://www.readbyqxmd.com/read/29075406/distribution-of-macrophages-and-plasma-cells-in-apical-periodontitis-and-their-relationship-with-clinical-and-image-data
#13
Stéphane V Azeredo, Sabrina C Brasil, Henrique Antunes, Fábio V Marques, Fábio R Pires, Luciana Armada
BACKGROUND: Macrophages and plasma cells play a key role in the regulation of innate and adaptive immunity. The aim of this study was to assess the presence of these cells in apical periodontitis and their distribution comparing with clinical and image data. MATERIAL AND METHODS: Thirty-three lesions were selected and divided in two groups (17 periapical cysts and 16 periapical granulomas). Immunoreactions using anti-CD68 and anti-CD138 antibodies were carried out; image analysis was performed with an optical microscope and 5 high-power fields from each slide were evaluated leading to an average score of immunoexpression...
September 2017: Journal of Clinical and Experimental Dentistry
https://www.readbyqxmd.com/read/29065165/highly-active-antiretroviral-therapy-for-critically-ill-hiv-patients-a-systematic-review-and-meta-analysis
#14
REVIEW
Hugo Boechat Andrade, Cassia Righy Shinotsuka, Ivan Rocha Ferreira da Silva, Camila Sunaitis Donini, Ho Yeh Li, Frederico Bruzzi de Carvalho, Pedro Emmanuel Alvarenga Americano do Brasil, Fernando Augusto Bozza, Andre Miguel Japiassu
INTRODUCTION: It is unclear whether the treatment of an HIV infection with highly active antiretroviral therapy (HAART) affects intensive care unit (ICU) outcomes. In this paper, we report the results of a systematic review and meta-analysis performed to summarize the effects of HAART on the prognosis of critically ill HIV positive patients. MATERIALS AND METHODS: A bibliographic search was performed in 3 databases (PubMed, Web of Science and Scopus) to identify articles that investigated the use of HAART during ICU admissions for short- and long-term mortality or survival...
2017: PloS One
https://www.readbyqxmd.com/read/29059411/clinical-and-laboratory-factors-associated-with-severe-dengue-a-case-control-study-of-hospitalized-children
#15
Mayumi Duarte Wakimoto, Luiz Antonio Bastos Camacho, Michelle Luiza Gonin, Patrícia Brasil
Background: More than half of the hospitalizations because of dengue in Brazil occurred in children <15 years of age in 2007 and 2008, an unexpected change in the epidemiological pattern. We sought to determine clinical and laboratory parameters associated with severity. Methods: A case-control study was conducted in three pediatric hospitals in Rio de Janeiro, Brazil; 233 laboratory-confirmed dengue patients were included: 69 cases and 164 controls. Specific clinical and laboratory factors were assessed using univariate and multivariate logistic regression models...
October 20, 2017: Journal of Tropical Pediatrics
https://www.readbyqxmd.com/read/29058954/migraine-and-cognitive-function-baseline-findings-from-the-brazilian-longitudinal-study-of-adult-health-elsa-brasil
#16
Cristina Pellegrino Baena, Alessandra Carvalho Goulart, Itamar de Souza Santos, Claudia Kimie Suemoto, Paulo Andrade Lotufo, Isabela Judith Bensenor
Background The association between migraine and cognitive performance is unclear. We analyzed whether migraine is associated with cognitive performance among participants of the Brazilian Longitudinal Study of Adult Health, ELSA-Brasil. Methods Cross-sectional analysis, including participants with complete information about migraine and aura at baseline. Headache status (no headaches, non-migraine headaches, migraine without aura and migraine with aura), based on the International Headache Society classification, was used as the dependent variable in the multilinear regression models, using the category "no headache" as reference...
January 1, 2017: Cephalalgia: An International Journal of Headache
https://www.readbyqxmd.com/read/29058102/procaspase-activating-compound-1-induces-apoptosis-in-trypanosoma-cruzi
#17
Emanuella de Castro, Thamile Luciane Reus, Alessandra Melo de Aguiar, Andrea Rodrigues Ávila, Tatiana de Arruda Campos Brasil de Souza
Some therapeutics for parasitic, cardiac and neurological diseases activate apoptosis. Therefore, the study of apoptotic proteins in pathogenic organisms is relevant. However, the molecular mechanism of apoptosis in unicellular organisms remain elusive, despite morphological evidence of its occurrence. In Trypanosoma cruzi, the causative agent of Chagas disease, metacaspase 3 (TcMCA3), seems to have a key role in parasite apoptosis. Accordingly, this work provides data concerning TcMCA3 regulation through its interaction with procaspase-activating compound 1 (PAC-1), a procaspase 3 activator...
October 20, 2017: Apoptosis: An International Journal on Programmed Cell Death
https://www.readbyqxmd.com/read/29054630/effects-of-land-use-and-seasonality-on-stream-water-quality-in-a-small-tropical-catchment-the-headwater-of-c%C3%A3-rrego-%C3%A3-gua-limpa-s%C3%A3-o-paulo-brazil
#18
Valdemir Rodrigues, Joan Estrany, Mauricio Ranzini, Valdir de Cicco, José Mª Tarjuelo Martín-Benito, Javier Hedo, Manuel E Lucas-Borja
Stream water quality is controlled by the interaction of natural and anthropogenic factors over a range of temporal and spatial scales. Among these anthropogenic factors, land cover changes at catchment scale can affect stream water quality. This work aims to evaluate the influence of land use and seasonality on stream water quality in a representative tropical headwater catchment named as Córrego Água Limpa (Sao Paulo, Brasil), which is highly influenced by intensive agricultural activities and urban areas...
October 17, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/29042894/genetic-association-of-the-period3-per3-clock-gene-with-bipolar-disorder
#19
Paulo Marcos Brasil Rocha, Simone Becho Campos, Fernando Silva Neves, Humberto Corrêa da Silva Filho
OBJECTIVE: Circadian rhythms have been linked to psychiatric disorders such as Depression and Bipolar Disorder (BD). Given previous evidences of sleep/circadian disturbances as well as the genetic susceptibility for BD, we decided to investigate the possible link between the PERIOD3 (Per3) circadian gene and BD. METHODS: This is a genetic association case (BD) vs. control study of the Per3 gene. We further subdivided our BD sample into "good sleepers" (PSQI ≤5) and "poor sleepers" (PSQI>5) according to the Pittsburgh Sleep Quality Index (PSQI) global score, and then we assessed genetic association of the Per3 gene with sleep quality in the BD group...
September 2017: Psychiatry Investigation
https://www.readbyqxmd.com/read/29039892/step-by-step-male-to-female-transsexual-surgery
#20
Rodrigo Uliano Moser da Silva, Fernando Jahn da Silva Abreu, Gabriel M V da Silva, João Vitor Quadra Vieira Dos Santos, Nelson Sivonei da Silva Batezini, Brasil Silva, Tiago Elias Rosito
INTRODUCTION: After the diagnosis of transsexualism is confirmed therapy commences with psychotherapeutic preparation for the conversion, and after conversion, long-term patient rehabilitation is maintained for at least two years. The indication for surgery is chronic discomfort caused by discord with the patient's natural gender, intense dislike of developing secondary sex characteristics and the onset of puberty. The surgical conversion of transsexuals is the main step in the complex care of these problematic patients (1)...
October 17, 2017: International Braz J Urol: Official Journal of the Brazilian Society of Urology
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