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A Meta-analysis of Outcomes Following Use of Somatostatin and Its Analogues for the Management of Enterocutaneous Fistulas

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https://www.readbyqxmd.com/read/22885696/a-meta-analysis-of-outcomes-following-use-of-somatostatin-and-its-analogues-for-the-management-of-enterocutaneous-fistulas
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Goher Rahbour, Muhammed R Siddiqui, Mohammad Rehan Ullah, Simon M Gabe, Janindra Warusavitarne, Carolynne J Vaizey
OBJECTIVE: Several randomized control trials (RCTs) have compared somatostatin and its analogues versus a control group in patients with enterocutaneous fistulas (ECF). This study meta-analyzes the literature and establishes whether it shows a beneficial effect on ECF closure. METHODS: We searched MEDLINE, EMBASE, CINAHL, Cochrane, and PubMed databases according to PRISMA guidelines. Seventy-nine articles were screened. Nine RCTs met the inclusion criteria. Statistical analyses were performed using Review Manager 5...
December 2012: Annals of Surgery
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