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Anterior segment optical coherence tomography

Yibing Zhang, Yuan Hu, Xiaodong Li, Xiaoru Shi, Feihong Xu, Hui Jia
The aim of the present study was to investigate the role of the limbal stem cells in corneal epithelial homeostasis in patients with peripheral corneal disease who received corneal transplantation surgery. This retrospective study enrolled 85 patients (85 eyes) with peripheral corneal lesion who underwent corneal transplantation at Department of Ophthalmology in First Hospital of Jilin University, Jilin, China. All patients during each follow-up period were examined for best corrected visual acuity, corneal reconstruction (assessed by slit-lamp biomicroscopy), anterior segment optical coherence tomography, and confocal microscopy...
June 2018: Experimental and Therapeutic Medicine
José Lamarca, Borja Salvador-Culla, Carlos Fernández-Vega, Rafael I Barraquer
PURPOSE: To report the long-term clinical outcomes of a patient with Terrien's marginal degeneration who underwent successful peripheral corneal cross-linking (CXL) to arrest progression. METHODS: Clinical assessment included uncorrected distance visual acuity (UDVA), corrected distance visual acuity (CDVA), corneal topography, anterior segment optical coherence tomography, ultrasonic pachymetry, corneal hysteresis, and corneal resistance factor. Eccentric epithelium-off CXL was performed in both eyes after limbal conjunctival resection...
June 1, 2018: Journal of Refractive Surgery
Jeferson Lautert, Dharmil Doshi, Francis W Price, Marianne O Price
PURPOSE: To evaluate remodeling of the corneal epithelium after epithelium-off corneal cross-linking (CXL). METHODS: In this prospective single-center study, 93 eyes of 93 patients with progressive keratoconus underwent standard CXL. The maximum keratometry was assessed before and after CXL with Scheimpflug imaging, and the epithelial thickness profile across the central 5 mm of the cornea was assessed with spectral-domain optical coherence tomography anterior segment imaging...
June 1, 2018: Journal of Refractive Surgery
Priya Narang, Ashar Agarwal, Amar Agarwal
PURPOSE: To describe the feasibility and efficacy of performing single-pass four-throw pupilloplasty for secondary angle-closure glaucoma post silicon oil tamponade. METHODS: The procedure was performed in five eyes of five patients. All the cases underwent silicon oil removal with single-pass four-throw pupilloplasty. Single-pass four-throw procedure involves a single pass of needle through the iris tissue that is to be apposed followed by taking four throws by passing the suture end through the loop that is withdrawn from the anterior chamber as in a modified Siepser's slip-knot technique...
June 1, 2018: European Journal of Ophthalmology
Judyta Jankowska-Szmul, Edward Wylegala
Purpose: We combined a clinical grading scale and swept source anterior segment OCT to describe the successful and failed CLASS. Material and Methods: 23 patients in the successful group and 17 patients in the failed group were compared in terms of the IBAGS grades and AS-OCT findings at one, three, and twelve months postoperatively. Results: The majority in the successful group presented shallow blebs (91%, 57%, and 52% at 1M, 3M, and 12M, resp...
2018: Journal of Healthcare Engineering
Reena Chopra, Pádraig J Mulholland, Vijay K Tailor, Roger S Anderson, Pearse A Keane
Importance: Current clinical methods for assessing strabismus can be prone to error. Binocular optical coherence tomography (OCT) has the potential to assess and quantify strabismus objectively and in an automated manner. Objective: To evaluate the use of a binocular OCT prototype to assess the presence and size of strabismus. Design, Setting, and Participants: Fifteen participants with strabismus were recruited in 2016 as part of the EASE study from Moorfields Eye Hospital National Health Service Foundation Trust, London, England, and 15 healthy volunteers underwent automated anterior segment imaging using the binocular OCT prototype...
May 31, 2018: JAMA Ophthalmology
Kelvin H Wan, Alexander K N Lam, Christopher Kai-Shun Leung
Importance: Whether optical coherence tomography angiography (OCT-A) outperforms OCT to detect glaucoma remains inconclusive. Objective: To compare (1) the diagnostic performance for detection of glaucoma and (2) the structure-function association between inner macular vessel density and inner macular thickness. Design, Setting, and Participants: This cross-sectional study included 115 patients with glaucoma and 35 healthy individuals for measurements of retinal thickness and retinal vessel density, segmented between the anterior boundary of internal limiting membrane and the posterior boundary of the inner plexiform layer, over the 3 × 3-mm2 macula using swept-source OCT...
May 31, 2018: JAMA Ophthalmology
Haomin Luo, Hongli Yang, Stuart K Gardiner, Christy Hardin, Glen P Sharpe, Joseph Caprioli, Shaban Demirel, Christopher A Girkin, Jeffrey M Liebmann, Christian Y Mardin, Harry A Quigley, Alexander F Scheuerle, Brad Fortune, Balwantray C Chauhan, Claude F Burgoyne
Purpose: To quantify the influence of ocular and demographic factors on central laminar depth (LD) in healthy participants. Methods: A total of 362 normal subjects underwent optical coherence tomography (OCT) enhanced depth imaging of the optic nerve head (ONH) with a 24 radial B-scan pattern aligned to the fovea-to-Bruch's membrane opening (BMO) axis. BMO, anterior lamina, anterior scleral canal opening (ASCO), Bruch's membrane (BM), and the peripapillary scleral surface were manually segmented...
May 1, 2018: Investigative Ophthalmology & Visual Science
Bret A Moore, Michel J Roux, Lionel Sebbag, Ann Cooper, Sydney G Edwards, Brian C Leonard, Denise M Imai, Stephen Griffey, Lynette Bower, Dave Clary, K C Kent Lloyd, Yann Hérault, Sara M Thomasy, Christopher J Murphy, Ala Moshiri
Purpose: The purpose of this study was to quantify the frequency and severity of ocular abnormalities affecting wild-type C57BL/6N mice, the most common strain used worldwide for the creation of single-gene knockouts. Methods: A total of 2773 animals (5546 eyes) were examined at one colony at UC Davis and in three more colonies at the Institut Clinique de la Souris in Strasbourg, France. Mice were examined at 15 to 16 weeks postnatal age by performing anterior segment biomicroscopy, posterior segment examination by indirect ophthalmoscopy, intraocular pressure measurement, and optical coherence tomography of anterior and posterior segment structures...
May 1, 2018: Investigative Ophthalmology & Visual Science
Mohamed Nagy Elmohamady, Walid Abdelghaffar, Ahmed Daifalla, Tamer Salem
Purpose: To evaluate femtosecond laser in flap and cap creation, detect some corneal biomechanical changes, and evaluate dry eye after laser in situ keratomileusis (LASIK), Femto-LASIK, and small incision lenticule extraction (SMILE) with 3-year follow-up. Patients and methods: Preoperative evaluation taken: full ophthalmic examination, Pentacam, ocular response analyzer, ocular surface disease index (OSDI), and tear breakup time (TBUT). LASIK flap was created using Moria microkeratome in 30 eyes (LASIK group) and using VisuMax femtosecond laser in 38 eyes (FS-LASIK group) and SMILE was done by VisuMax in 35 eyes (SMILE group)...
2018: Clinical Ophthalmology
Priya Narang, Amar Agarwal, Dhivya Ashok Kumar, Ashvin Agarwal, Ashar Agarwal
The technique, feasibility, and results of a new 25-gauge trocar-anterior chamber maintainer (ACM) designed for maintaining intraoperative fluid infusion is described in this prospective interventional analysis. The 25-gauge trocar-ACM with an overall length of the trocar blade of 6.0 mm, cannula length of 4.0 mm, and the cannula tip beveled at 45 degrees to the base was designed and used in all the cases. The dimensions of the sclerotomy wound that comprised of the internal ostium, external ostium, wound length, and the time interval for wound apposition in the postoperative period was analyzed by spectral-domain anterior segment optical coherence tomography...
May 25, 2018: Journal of Cataract and Refractive Surgery
Saurabh Choudhry, Neha Goel, Aanchal Mehta, Nidhi Mahajan
Postoperative opacification of a hydrophilic acrylic intraocular lens (IOL) is an uncommon complication. A 57-year-old diabetic female who had undergone phacoemulsification with IOL implantation in her right eye 16 years back presented with diminution of vision in the same eye for 3 years. Significant IOL opacification was observed clinically and anterior segment optical coherence tomography clearly delineated the intraoptic deposits, sparing the haptics, and edges of the optic. IOL explant and exchange was performed leading to restoration of visual acuity to 6/9...
June 2018: Indian Journal of Ophthalmology
Qihua Le, C Michael Samson, Sophie X Deng
PURPOSE: To report a case of corneal neovascularization misdiagnosed as total limbal stem cell deficiency (LSCD). METHODS: This is a case report of a 61-year-old woman who has a history of bilateral idiopathic scleritis, keratitis, and uveitis for more than 20 years. She was diagnosed with total LSCD in her left eye based on clinical presentation alone and was confirmed as a candidate for limbal transplantation at several major tertiary eye care centers in the United States...
May 16, 2018: Cornea
Justin C Galvin, Paula Berdoukas, Adrian T Fung
Purpose: We present two cases of late-onset capsular bag distension syndrome (CBDS). Observations: Two female patients were referred with decreased visual acuity and blurred vision. They had both undergone uncomplicated phacoemulsification and intraocular lens implantation into the capsular bag, seven and 13 years prior.Slit-lamp biomicroscopy and anterior segment optical coherence tomography demonstrated milky fluid between the intraocular lens and posterior capsules, consistent with late-onset capsular bag distension syndrome...
June 2018: American Journal of Ophthalmology Case Reports
Helena Yuri Kurimori, Makoto Inoue, Akito Hirakata
Purpose: To report the findings and surgical techniques on two cases of severe tilting of an intraocular lens (IOL) that had been implanted with intrascleral fixation and the tilting was detected by anterior segment optical coherence tomography (AS-OCT). Observations: Two patients underwent flanged intrascleral fixation of an IOL with the double needle technique. AS-OCT showed that the tilt of IOL was 25.3° in Case 1 and was 38.1° in Case 2, and a second surgery was planned to reduce the IOL tilt...
June 2018: American Journal of Ophthalmology Case Reports
Hiromasa Hirai, Shinji Maruoka, Tadanobu Yoshikawa, Nahoko Ogata
Purpose: To report a case that had a progressive decrease in the visual acuity caused by a progressive increase in the hyperopia due to a flattening of the cornea. Observations: A 50-year-old woman complained of decreased vision in both eyes. Her decimal best-corrected visual acuity was 1.2 in the right and 0.5 in the left eyes, and the refractive error (spherical equivalent) was +3.75 diopters (D) for the right eye and +6.5 D for the left eye. Slit-lamp examinations showed clear corneas but Descemet's folds and fine pigmentations and opacities were present beneath the corneal epithelium in both eyes...
June 2018: American Journal of Ophthalmology Case Reports
Ryan M Jaber, Mark Harrod, Jeffrey M Goshe
Purpose: To report a case of spontaneous regression of optical coherence tomography (OCT) and confocal microscopy-supported epithelial downgrowth associated with clear corneal phacoemulsification wound. Observations: A 66-year-old Caucasian male presented two years after phacoemulsification in the left eye with an enlarging cornea endothelial lesion in that eye. His early post-operative course had been complicated by corneal edema and iris transillumination defects...
June 2018: American Journal of Ophthalmology Case Reports
B Çakır, E Doğan, E Çelik, T Babashli, T Uçak, G Alagöz
PURPOSE: To investigate the effects of artificial tear treatment on central corneal epithelial thickness, and central, mid-peripheral and peripheral corneal thicknesses in patients with dry eye disease (DED). MATERIAL-METHODS: Patients with DED underwent ocular examinations, including Schirmer-2 test, slit lamp examination for tear break-up time (BUT), corneal topography (CT) for measuring mean central, mid-peripheral and peripheral corneal thickness values and anterior segment optic coherence tomography (AS-OCT) for obtaining central corneal epithelial thickness...
May 15, 2018: Journal Français D'ophtalmologie
Mehtap Çağlayan, Pınar Kösekahya, Canan Gürdal, Özge Saraç
Objectives: To compare the effectiveness of electrocoagulation and conventional medical drops for treatment of conjunctivochalasis using anterior segment-optical coherence tomography (AS-OCT). Materials and Methods: Forty eyes of 20 patients with bilateral conjunctivochalasis were included in this prospective study. Twenty eyes of 10 patients were assigned to Group 1 and underwent electrocoagulation. The other 20 eyes of 10 patients were assigned to Group 2 and received conventional medical treatment consisting of non-steroidal antiinflammatory drop (topical 0...
April 2018: Turkish Journal of Ophthalmology
Y Di, J J Ye, D H Li
Objective: To analyze the relationship between optical coherence tomography(OCT) performance and visual acuity of patients with acute retinal necrosis (ARN). Methods: Retrospective analysis was performed on the patients diagnosed with ARN at the ophthalmology department of Peking union hospital during October 2011 and May 2016. Fourteen patients (15 eyes), 9 males and 5 females, whose anterior and posterior inflammation disappeared and the retinal necrosis lesion in the fundus of the eye subsided were included...
May 11, 2018: [Zhonghua Yan Ke za Zhi] Chinese Journal of Ophthalmology
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