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renal mass biopsy

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https://www.readbyqxmd.com/read/28299630/the-role-of-interventional-radiology-techniques-in-the-management-of-renal-angiomyolipomas
#1
REVIEW
Ryan M Kiefer, S William Stavropoulos
PURPOSE OF REVIEW: Although benign, renal angiomyolipoma (AML) may lead to serious complications without appropriate management. The purpose of this review is to describe the role of and evidence for interventional radiology techniques in the management of patients with AML. RECENT FINDINGS: For patients with renal masses and non-diagnostic imaging studies, image-guided percutaneous biopsy is found to be highly accurate and useful in directing patient management...
May 2017: Current Urology Reports
https://www.readbyqxmd.com/read/28265233/leiomyosarcoma-of-the-renal-vein-analysis-of-outcome-and-prognostic-factors-in-the-world-case-series-of-67-patients
#2
Marko Novak, Andraz Perhavec, Katherine E Maturen, Snezana Pavlovic Djokic, Simona Jereb, Darja Erzen
BACKGROUND: Leiomyosarcoma is a rare malignant mesenchymal tumour. Some cases of leiomyosarcoma of the renal vein (LRV) have been reported in the literature, but no analysis of data and search for prognostic factors have been done so far. The aim of this review was to describe the LRV, to analyse overall survival (OS), local recurrence free survival (LRFS) and distant metastases free survival (DMFS) in LRV world case series and to identify significant predictors of OS, LRFS and DMFS. METHODS: Cases from the literature based on PubMed search and a case from our institution were included...
March 1, 2017: Radiology and Oncology
https://www.readbyqxmd.com/read/28263135/a-case-report-of-a-renal-diffuse-b-cell-lymphoma
#3
Raunak D Patel, Colton Walker, Daniel J Canter
Diffuse large B-cell lymphomas (DLBCL) are the most common lymphomas worldwide. They also appear to be the most common primary retroperitoneal lymphomas, but this presentation is relatively uncommon in the literature. Retroperitoneal masses, including lymphomas, often present with nonspecific symptoms and laboratory values, necessitating radiographic assessment and consideration of mass biopsy prior to the initiation of treatment. Here we present a case of a primary retroperitoneal DLBCL as well as a review of the clinical presentation, imaging findings, and differential diagnosis of such tumors...
February 2017: Canadian Journal of Urology
https://www.readbyqxmd.com/read/28255621/irreversible-electroporation-of-small-renal-masses-suboptimal-oncologic-efficacy-in-an-early-series
#4
Noah E Canvasser, Igor Sorokin, Aaron H Lay, Monica S C Morgan, Asim Ozayar, Clayton Trimmer, Jeffrey A Cadeddu
PURPOSE: To report on the first short-term oncologic outcomes of percutaneous irreversible electroporation for small renal masses. METHODS: Patients with cT1a renal masses treated with irreversible electroporation from April 2013 through December 2016 were reviewed. Small, low complexity tumors were generally selected for irreversible electroporation using the NanoKnife(®) System (Angiodynamics, Latham, NY, USA). Surveillance imaging was performed post-operatively, and survival analysis was completed using the Kaplan-Meier method...
March 2, 2017: World Journal of Urology
https://www.readbyqxmd.com/read/28251484/update-on-renal-mass-biopsy
#5
REVIEW
Miki Haifler, Alexander Kutikov
Renal masses are diagnosed with an increasing frequency. However, a significant proportion of these masses are benign, and the majority of malignant tumors are biologically indolent. Furthermore, renal tumors are often harbored by the elderly and comorbid patients. As such, matching of renal tumor biology to appropriate treatment intensity is an urgent clinical need. Renal mass biopsy is currently a very useful clinical tool that can assist with critical clinical decision-making in patients with renal mass...
April 2017: Current Urology Reports
https://www.readbyqxmd.com/read/28242092/-cutaneous-involvement-in-t-lymphoblastic-lymphoma
#6
C Nascimbeni, S Chantepie, C Brugiere, F Comoz, V Salaun, L Verneuil
BACKGROUND: Lymphoblastic lymphoma (LBL) is a rare form of non-Hodgkin's lymphoma (NHL). Cutaneous LBL is seen in less than 20% of patients. PATIENTS AND METHODS: Herein, we report the case of a 66-year-old male patient without any previous disease history of note and who was presenting a gradually spreading tumoral lesion of the scalp, several purplish macules and nodules on the trunk, and a single spinal adenopathy. A thoracic-abdominal-pelvic CT scan performed for acute renal failure, revealed extensive infiltration of retroperitoneal tissue...
February 24, 2017: Annales de Dermatologie et de Vénéréologie
https://www.readbyqxmd.com/read/28237283/ablative-therapies-for-renal-tumors-patient-selection-treatment-planning-and-follow-up
#7
Jean-Michel Correas, Christophe Delavaud, Jules Gregory, Thomas Le Guilchet, Lionel Lamhaut, Marc-Olivier Timsit, Arnaud Méjean, Olivier Hélénon
The increased use of abdominal imaging has led to a major increase in small renal tumors incidence particularly in the elderly population. Their management is evolving with the development of percutaneous ablation, particularly radiofrequency ablation, cryoablation, and microwave ablation. The typical indications that must be validated by a multidisciplinary committee include solid tumors less than 3cm in patients with multiple comorbidity factors (including age), contraindications to surgery, hereditary renal cancer, bilateral renal tumors, solitary kidney, pre-existing chronic kidney disease, or at high risk of predialysis renal function after partial nephrectomy...
February 2017: Seminars in Ultrasound, CT, and MR
https://www.readbyqxmd.com/read/28237282/the-current-role-of-biopsy-in-the-diagnosis-of-renal-tumors
#8
Nicole Curci, Elaine M Caoili
The role of percutaneous renal mass biopsy has continued to grow in the last decade. The incidence of small (≤4cm) renal masses has increased dramatically over the past 15 years, attributed to increased use of cross-sectional imaging and subsequent discovery of small renal masses that would otherwise go undetected. Despite increased early detection, there has been no change in the mortality rate from renal cell carcinoma over the past 15 years. Many small renal masses are not life-limiting, and imaging lacks specificity in distinguishing malignant from nonmalignant small renal masses...
February 2017: Seminars in Ultrasound, CT, and MR
https://www.readbyqxmd.com/read/28237280/multiparametric-magnetic-resonance-imaging-of-solid-renal-tumors-a-practical-algorithm
#9
Francois Cornelis, Nicolas Grenier
Although preoperative classification of solid renal tumors was performed by percutaneous biopsy until now, research teams have demonstrated the potential interest of imaging to characterize noninvasively different renal tumor subtypes, in particular, with multiparametric magnetic resonance (MR) imaging. By combining all the imaging MR features successively reported in the literature and following a practical algorithm based on a step-by-step reading of the MR images, readers are now able to identify several imaging profiles, which appeared specific of each renal tumor subtypes...
February 2017: Seminars in Ultrasound, CT, and MR
https://www.readbyqxmd.com/read/28237279/diagnosis-of-renal-angiomyolipomas-classic-fat-poor-and-epithelioid-types
#10
Masahiro Jinzaki, Stuart G Silverman, Hirotaka Akita, Shuji Mikami, Mototsugu Oya
With the increasing discovery of small renal masses with cross-sectional imaging, there has been the concomitant rise in their treatment. With the intent of early curative surgery for a presumed renal cell carcinoma, many renal masses are being resected at surgery without a confirmed diagnosis. Many of them are benign, and some are angiomyolipomas. The diagnosis of renal angiomyolipoma using imaging is, therefore, is as important as ever. Although most, if not all angiomyolipomas with abundant fat are diagnosed readily, some have too little fat to be detected with imaging...
February 2017: Seminars in Ultrasound, CT, and MR
https://www.readbyqxmd.com/read/28197683/aorta-lesion-attenuation-difference-alad-on-contrast-enhanced-ct-a-potential-imaging-biomarker-for-differentiating-malignant-from-benign-oncocytic-neoplasms
#11
Manish Dhyani, Joseph R Grajo, Dayron Rodriguez, Zhikui Chen, Adam Feldman, Rosemary Tambouret, Debra A Gervais, Ronald S Arellano, Peter F Hahn, Anthony E Samir
OBJECTIVE: To evaluate whether the Aorta-Lesion-Attenuation-Difference on contrast-enhanced CT can aid in the differentiation of malignant and benign oncocytic renal neoplasms. MATERIALS AND METHODS: Two independent cohorts-an initial (biopsy) dataset and a validation (surgical) dataset-with oncocytomas and chromophobe renal cell carcinomas (chRCC) were included in this IRB-approved retrospective study. A region of interest was placed on the renal mass and abdominal aorta on the same CT image slice to calculate an Aorta-Lesion-Attenuation-Difference (ALAD)...
February 14, 2017: Abdominal Radiology
https://www.readbyqxmd.com/read/28188595/should-small-renal-masses-be-biopsied
#12
REVIEW
Ricardo R N Leão, Ardalan E Ahmad, Patrick O Richard
Over the last few decades, the incidence of renal cell carcinomas (RCCs) has been steadily increasing. This is primarily due to an increase in detection of small renal masses (SRMs) as a result of widespread utilization of abdominal imaging. Interestingly, up to 30% of incidentally discovered SRMs (solid lesions measuring ≤4 cm) are benign, and consequently, the definitive treatment of all SRMs is associated with a considerable risk of overtreatment. To decrease the overtreatment rate, renal tumour biopsy (RTB) has been advocated as a safe alternative to identify the pretreatment histology of these SRMs...
January 2017: Current Urology Reports
https://www.readbyqxmd.com/read/28184961/renal-mass-biopsy-and-thermal-ablation-should-biopsy-be-performed-before-or-during-the-ablation-procedure
#13
Shane A Wells, Vincenzo K Wong, Tyler A Wittmann, Meghan G Lubner, Sara L Best, Timothy J Ziemlewicz, J Louis Hinshaw, Fred T Lee, E Jason Abel
PURPOSE: To determine if renal mass biopsy should be performed before or during the ablation procedure with emphasis on complications and rate of ablation for renal cell carcinomas (RCC), benign tumors, and small renal masses without a histologic diagnosis. METHODS: This HIPAA-compliant, single-center retrospective study was performed under a waiver of informed consent from the institutional review board. Two hundred eighty-four consecutive patients with a small renal mass (≤4...
February 9, 2017: Abdominal Radiology
https://www.readbyqxmd.com/read/28181337/deficiency-of-the-sphingosine-1-phosphate-lyase-sgpl1-is-associated-with-congenital-nephrotic-syndrome-and-congenital-adrenal-calcifications
#14
Andreas R Janecke, Ruijuan Xu, Elisabeth Steichen-Gersdorf, Siegfried Waldegger, Andreas Entenmann, Thomas Giner, Iris Krainer, Lukas A Huber, Michael W Hess, Yaacov Frishberg, Hila Barash, Shay Tzur, Nira Schreyer-Shafir, Rivka Sukenik-Halevy, Tania Zehavi, Annick Raas-Rothschild, Cungui Mao, Thomas Müller
We identified two unrelated consanguineous families with three children affected by the rare association of congenital nephrotic syndrome (CNS) diagnosed in the first days of life, of hypogonadism, and of prenatally detected adrenal calcifications, associated with congenital adrenal insufficiency in one case. Using exome sequencing and targeted Sanger sequencing, two homozygous truncating mutations, c.1513C>T (p.Arg505*) and c.934delC (p.Leu312Phefs*30), were identified in SGPL1-encoding sphingosine-1-phosphate (S1P) lyase 1...
April 2017: Human Mutation
https://www.readbyqxmd.com/read/28177700/ct-guided-biopsy-of-entirely-endophytic-small-renal-masses-diagnostic-rates-and-complications-using-standard-dose-and-reduced-dose-ct-protocols
#15
Mi-Hyun Kim
OBJECTIVE: The objective of this study was to compare diagnostic rates and complications using standard-dose and reduced-dose CT protocols for CT-guided biopsies of entirely endophytic small renal masses. MATERIALS AND METHODS: A total of 73 patients with 74 tumors underwent CT-guided biopsy of entirely endophytic small renal masses (≤ 4 cm). Diagnostic rates, histologic findings, radiation doses, complication rates, and procedure duration were assessed by retrospective review of charts and images and were compared for the standard-dose and reduced-dose groups...
February 8, 2017: AJR. American Journal of Roentgenology
https://www.readbyqxmd.com/read/28159492/multi-quadrant-biopsy-technique-improves-diagnostic-ability-in-large-heterogeneous-renal-masses-abel-ej-heckman-je-hinshaw-l-best-s-lubner-m-jarrard-df-downs-tm-nakada-sy-lee-ft-jr-huang-w-ziemlewicz-t-j-urol-2015-oct-194-4-886-91-epub-2015-mar-30-doi-10-1016
#16
Raman Jay, J E Heckman, L Hinshaw, S Best, M Lubner, D F Jarrard, T M Downs, S Y Nakada, F T Lee, W Huang, T Ziemlewicz
PURPOSE: Percutaneous biopsy obtained from a single location is prone to sampling error in large heterogeneous renal masses, leading to nondiagnostic results or failure to detect poor prognostic features. We evaluated the accuracy of percutaneous biopsy for large renal masses using a modified multi-quadrant technique vs. a standard biopsy technique. MATERIALS AND METHODS: Clinical and pathological data for all patients with cT2 or greater renal masses who underwent percutaneous biopsy from 2009 to 2014 were reviewed...
March 2017: Urologic Oncology
https://www.readbyqxmd.com/read/28158993/comparative-differential-proteomic-analysis-of-minimal-change-disease-and-focal-segmental-glomerulosclerosis
#17
Vanessa Pérez, Dolores López, Ester Boixadera, Meritxell Ibernón, Anna Espinal, Josep Bonet, Ramón Romero
BACKGROUND: Minimal change disease (MCD) and primary focal segmental glomerulosclerosis (FSGS) are glomerular diseases characterized by nephrotic syndrome. Their diagnosis requires a renal biopsy, but it is an invasive procedure with potential complications. In a small biopsy sample, where only normal glomeruli are observed, FSGS cannot be differentiated from MCD. The correct diagnosis is crucial to an effective treatment, as MCD is normally responsive to steroid therapy, whereas FSGS is usually resistant...
February 3, 2017: BMC Nephrology
https://www.readbyqxmd.com/read/28144859/pulmonary-metastasis-from-urothelial-carcinoma-of-the-upper-urinary-tract-29%C3%A2-years-after-nephrectomy
#18
Koji Kawaguchi, Toshiki Okasaka, Takayuki Fukui, Koichi Fukumoto, Shota Nakamura, Shuhei Hakiri, Naoki Ozeki, Kohei Yokoi
BACKGROUND: Late pulmonary metastasis from urothelial carcinoma (UC) of the upper urinary tract is extremely rare. CASE PRESENTATION: A 76-year-old man was referred to our hospital due to an abnormal shadow on chest X-ray. He had a history of left nephrectomy with a diagnosis of UC in the renal pelvis 29 years previously. Computed tomography showed a mass lesion in the right middle lobe of the lung that measured 4.9 cm in diameter. A transbronchial biopsy revealed the tumor to be metastatic pulmonary UC, and he underwent right middle lobectomy of the lung...
December 2017: Surgical Case Reports
https://www.readbyqxmd.com/read/28139293/clinical-biopsy-and-mass-spectrometry-findings-of-renal-gelsolin-amyloidosis
#19
Sanjeev Sethi, Surendra Dasari, Md Shahrier Amin, Julie A Vrana, Jason D Theis, Mariam P Alexander, Paul J Kurtin
Gelsolin amyloidosis is a rare type of amyloidosis typically involving the cranial and peripheral nerves, but rarely the kidney. Here we report the clinical, kidney biopsy, and mass spectrometry findings in 12 cases of renal gelsolin amyloidosis. Of the 12 patients, five were men and seven were women with mean age at diagnosis of 63.8 years. Gelsolin amyloidosis was most common in Caucasians (six patients) and Asians (four patients), and included one each African-American and Hispanic patients. Nephrotic syndrome was the most common cause of biopsy, although most patients also had progressive loss of kidney function...
January 27, 2017: Kidney International
https://www.readbyqxmd.com/read/28126220/image-guided-renal-interventions
#20
REVIEW
Sharath K Bhagavatula, Paul B Shyn
Image-guided renal biopsies have an increasing role in clinical practice. Renal mass and renal parenchymal biopsy indications, techniques, and other clinical considerations are reviewed in this article. Image-guided renal mass ablation shows significant promise and increasing clinical utility as more studies demonstrate its safety and efficacy. Renal mass ablation indications, techniques, and other considerations are also reviewed.
March 2017: Radiologic Clinics of North America
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