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Health economics and outcomes research

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https://www.readbyqxmd.com/read/28319481/application-of-telepractice-for-head-and-neck-cancer-management-a-review-of-speech-language-pathology-service-models
#1
Elizabeth C Ward, Laurelie R Wall, Clare L Burns, Bena Cartmill, Anne J Hill
PURPOSE OF REVIEW: Head and neck cancer (HNC) is a complex and heterogeneous disease, requiring specialist intervention from a multidisciplinary team including speech language pathology (SLP). Unfortunately, multiple patient and service-related challenges exist which currently limit equitable access to SLP support for all individuals. This review highlights the existing evidence for different telepractice models designed to help patients and services optimize management of swallowing and communication disorders arising from HNC...
March 17, 2017: Current Opinion in Otolaryngology & Head and Neck Surgery
https://www.readbyqxmd.com/read/28303533/urban-health-in-tanzania-questioning-the-urban-advantage
#2
Francis Levira, Gemma Todd
How are health inequalities articulated across urban and rural spaces in Tanzania? This research paper explores the variations, differences, and inequalities, in Tanzania's health outcomes-to question both the idea of an urban advantage in health and the extent of urban-rural inequalities in health. The three research objectives aim to understand: what are the health differences (morbidity and mortality) between Tanzania's urban and rural areas; how are health inequalities articulated within Tanzania's urban and rural areas; and how are health inequalities articulated across age groups for rural-urban Tanzania? By analyzing four national datasets of Tanzania (National Census, Household Budget Survey, Demographic Health Survey, and Health Demographic Surveillance System), this paper reflects on the outcomes of key health indicators across these spaces...
March 16, 2017: Journal of Urban Health: Bulletin of the New York Academy of Medicine
https://www.readbyqxmd.com/read/28295894/cost-effectiveness-analysis-appraisal-and-application-an-emergency-medicine-perspective
#3
Michael D April, Brian P Murray
Cost-effectiveness is an important goal for emergency care delivery. The many diagnostic, treatment, and disposition decisions made in the emergency department (ED) have a significant impact upon healthcare resource utilization. Cost-effectiveness analysis (CEA) is an analytic tool to optimize these resource allocation decisions through the systematic comparison of costs and effects of alternative healthcare decisions. Yet few emergency medicine leaders and policy-makers have any formal training in CEA methodology...
March 10, 2017: Academic Emergency Medicine: Official Journal of the Society for Academic Emergency Medicine
https://www.readbyqxmd.com/read/28292764/adult-and-adolescent-livestock-productive-asset-transfer-programmes-to-improve-mental-health-economic-stability-and-family-and-community-relationships-in-rural-south-kivu-province-democratic-republic-of-congo-a-protocol-of-a-randomised-controlled-trial
#4
Anjalee Kohli, Nancy A Perrin, Mitima Mpanano Remy, Mirindi Bacikenge Alfred, Kajabika Binkurhorhwa Arsene, Mwinja Bufole Nadine, Banyewesize Jean Heri, Mitima Murhula Clovis, Nancy Glass
INTRODUCTION: People living in poverty have limited access to traditional financial institutions. Microfinance programmes are designed to meet this gap and show promise in improving income, economic productivity and health. Our Congolese-US community academic research partnership developed two livestock productive asset transfer programmes, Pigs for Peace (PFP) and Rabbits for Resilience (RFR), to address the interlinked health, social and economic well-being of individuals, their families and communities...
March 14, 2017: BMJ Open
https://www.readbyqxmd.com/read/28292481/development-of-an-official-guideline-for-the-economic-evaluation-of-drugs-medical-devices-in-japan
#5
Takeru Shiroiwa, Takashi Fukuda, Shunya Ikeda, Tomoyuki Takura, Kensuke Moriwaki
OBJECTIVES: In Japan, cost-effectiveness evaluation was implemented on a trial basis from fiscal year 2016. The results will be applied to the future repricing of drugs and medical devices. On the basis of a request from the Central Social Insurance Medical Council (Chuikyo), our research team drafted the official methodological guideline for trial implementation. Here, we report the process of developing and the contents of the official guideline for cost-effectiveness evaluation. METHODS: The guideline reflects discussions at the Chuikyo subcommittee (e...
March 2017: Value in Health: the Journal of the International Society for Pharmacoeconomics and Outcomes Research
https://www.readbyqxmd.com/read/28285379/evolocumab-for-treating-primary-hypercholesterolaemia-and-mixed-dyslipidaemia-an-evidence-review-group-perspective-of-a-nice-single-technology-appraisal
#6
Christopher Carroll, Paul Tappenden, Rachid Rafia, Jean Hamilton, Duncan Chambers, Mark Clowes, Paul Durrington, Nadeem Qureshi, Anthony S Wierzbicki
As part of its single technology appraisal (STA) process, the UK National Institute for Health and Care Excellence (NICE) invited the manufacturer of evolocumab (Amgen) to submit evidence on the clinical and cost effectiveness of evolocumab. The appraisal assessed evolocumab as monotherapy or in combination with a statin with or without ezetimibe, or in combination with ezetimibe (without statin therapy), in adult patients with primary hypercholesterolaemia (which includes mixed dyslipidaemia), for whom statins do not provide optimal control of their low-density lipoprotein cholesterol (LDL-C) levels and/or for whom statins are contraindicated or not tolerated...
March 11, 2017: PharmacoEconomics
https://www.readbyqxmd.com/read/28282249/health-provider-views-on-improving-antiretroviral-therapy-adherence-among-men-who-have-sex-with-men-in-coastal-kenya
#7
Murugi Micheni, Bernadette K Kombo, Andrew Secor, Jane M Simoni, Don Operario, Elise M van der Elst, Peter Mugo, Jennifer Kanungi, Eduard J Sanders, Susan M Graham
HIV-positive Kenyan men who have sex with men (MSM) are a highly stigmatized group facing barriers to care engagement and antiretroviral therapy (ART) adherence. Because care providers' views are important in improving outcomes, we sought the perspective of those serving MSM patients on how to optimize ART adherence in a setting where same-sex behavior is criminalized. We conducted 4 focus group discussions with a total of 29 healthcare workers (HCWs) experienced in providing HIV care to MSM. The semistructured, open-ended topic guide used was based on an access-information-motivation-proximal cues model of adherence, with added focus on trust in providers, stigma, and discrimination...
March 2017: AIDS Patient Care and STDs
https://www.readbyqxmd.com/read/28280000/increased-household-financial-strain-the-great-recession-and-child-health-findings-from-the-uk-millennium-cohort-study
#8
Caoimhe McKenna, Catherine Law, Anna Pearce
BACKGROUND: There is a growing body of evidence associating financial strain (FS) with poor health but most of this research has been cross-sectional and adult-focused. During the 'Great Recession' many UK households experienced increased FS. The primary aim of this study was to determine the impact of increased FS on child health. METHODS: We analysed the Millennium Cohort Study, a longitudinal study of children born in the UK between 2000 and 2002. Surveys at 7 years (T1, 2008) and 11 years (T2, 2012) spanned the 'Great Recession'...
March 9, 2017: BMJ Open
https://www.readbyqxmd.com/read/28279679/preventive-healthcare-for-young-children-a-systematic-review-of-interventions-in-primary-care
#9
REVIEW
Karyn E Alexander, Bianca Brijnath, Ruby Biezen, Kerry Hampton, Danielle Mazza
High rates of preventable health problems amongst children in economically developed countries have prompted governments to seek pathways for early intervention. We systematically reviewed the literature to discover what primary care-targeted interventions increased preventive healthcare (e.g. review child development, growth, vision screening, social-emotional health) for preschool children, excluding vaccinations. MEDLINE, EMBASE, CINAHL, and Cochrane databases were searched for published intervention studies, between years 2000 and 2014, which reflected preventive health activities for preschool children, delivered by health practitioners...
March 6, 2017: Preventive Medicine
https://www.readbyqxmd.com/read/28278559/online-support-groups-for-women-with-breast-cancer
#10
REVIEW
Eilis McCaughan, Kader Parahoo, Irene Hueter, Laurel Northouse, Ian Bradbury
BACKGROUND: Survival rates for women with a diagnosis of breast cancer continue to improve. However, some women may experience physical, psychological and emotional effects post diagnosis, throughout treatment and beyond. Support groups can provide opportunities for people to share their experiences and learn from others. As the number of online support groups increases, more and more women with breast cancer will likely access them. OBJECTIVES: To assess effects of online support groups on the emotional distress, uncertainty, anxiety, depression and quality of life (QoL) of women with breast cancer...
March 10, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28271978/lessons-from-cuba-for-global-precision-medicine-cyp2d6-genotype-is-not-a-robust-predictor-of-cyp2d6-ultrarapid-metabolism
#11
Pedro Dorado, Idilio González, María Eugenia G Naranjo, Fernando de Andrés, Eva María Peñas-Lledó, Luis Ramón Calzadilla, Adrián LLerena
A long-standing question and dilemma in precision medicine is whether and to what extent genotyping or phenotyping drug metabolizing enzymes such as CYP2D6 can be used in real-life global clinical and societal settings. Although in an ideal world using both genotype and phenotype biomarkers are desirable, this is not always feasible for economic and practical reasons. Moreover, an additional barrier for clinical implementation of precision medicine is the lack of correlation between genotype and phenotype, considering that most of the current methods include only genotyping...
January 2017: Omics: a Journal of Integrative Biology
https://www.readbyqxmd.com/read/28270214/research-capacity-strengthening-for-sexual-and-reproductive-health-a-case-study-from-latin-america
#12
REVIEW
Rita Kabra, Marco Castillo, Mercedes Melián, Moazzam Ali, Lale Say, A Metin Gulmezoglu
An essential, but often overlooked part of health promotion and development support to achieve self-sufficiency in developing countries is the concomitant need to build and strengthen research capacity. This is even more challenging and critical in the area of sexual and reproductive health because of diverse interplay of socio cultural, religious, economic factors in relation to reproductive health.This paper presents the case study of HRP's efforts to build research capacity in Latin America by studying and analyzing the 5-year history of institutional development support to an institution in Paraguay...
March 7, 2017: Reproductive Health
https://www.readbyqxmd.com/read/28270105/economic-evaluation-of-a-behavioral-intervention-versus-brief-advice-for-substance-use-treatment-in-pregnant-women-results-from-a-randomized-controlled-trial
#13
Xiao Xu, Kimberly A Yonkers, Jennifer Prah Ruger
BACKGROUND: Substance use in pregnancy is associated with severe maternal and fetal morbidities and substantial economic costs. However, few studies have evaluated the cost-effectiveness of substance use treatment programs in pregnant women. The purpose of this study was to evaluate the economic impact of a behavioral intervention that integrated motivational enhancement therapy with cognitive behavioral therapy (MET-CBT) for treatment of substance use in pregnancy, in comparison with brief advice...
March 7, 2017: BMC Pregnancy and Childbirth
https://www.readbyqxmd.com/read/28265719/health-state-utility-values-and-patient-reported-outcomes-before-and-after-vertebral-and-non-vertebral-fractures-in-an-osteoporosis-clinical-trial
#14
T Imai, S Tanaka, K Kawakami, T Miyazaki, H Hagino, M Shiraki
We assessed the health state utility value (HSUV) reductions associated with vertebral fractures using data collected in the Japanese Osteoporosis Intervention Trial-03 (JOINT-03). Our analysis revealed that assessment of HSUVs after morphometric vertebral fracture is important to capture the burden of vertebral fractures. INTRODUCTION: Evaluation of the HSUV after fracture is important to calculate the quality-adjusted life years (QALYs) of osteoporosis patients, which is essential information in the context of health economic evaluation...
March 6, 2017: Osteoporosis International
https://www.readbyqxmd.com/read/28265347/value-added-medicines-what-value-repurposed-medicines-might-bring-to-society
#15
Mondher Toumi, Cécile Rémuzat
Background & objectives: Despite the wide interest surrounding drug repurposing, no common terminology has been yet agreed for these products and their full potential value is not always recognised and rewarded, creating a disincentive for further development. The objectives of the present study were to assess from a wide perspective which value drug repurposing might bring to society, but also to identify key obstacles for adoption of these medicines and to discuss policy recommendations. Methods: A preliminary comprehensive search was conducted to assess how the concept of drug repurposing was described in the literature...
2017: Journal of Market Access & Health Policy
https://www.readbyqxmd.com/read/28262925/washout-policies-in-long-term-indwelling-urinary-catheterisation-in-adults
#16
REVIEW
Ashley J Shepherd, William G Mackay, Suzanne Hagen
BACKGROUND: People requiring long-term bladder draining with an indwelling catheter can experience catheter blockage. Regimens involving different solutions can be used to wash out catheters with the aim of preventing blockage. This is an update of a review published in 2010. OBJECTIVES: To determine if certain washout regimens are better than others in terms of effectiveness, acceptability, complications, quality of life and critically appraise and summarise economic evidence for the management of long-term indwelling urinary catheterisation in adults...
March 6, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28262598/effectiveness-and-cost-effectiveness-of-a-nurse-delivered-intervention-to-improve-adherence-to-treatment-for-hiv-a-pragmatic-multicentre-open-label-randomised-clinical-trial
#17
Marijn de Bruin, Edwin J M Oberjé, Wolfgang Viechtbauer, Hans-Erik Nobel, Mickaël Hiligsmann, Cees van Nieuwkoop, Jan Veenstra, Frank J Pijnappel, Frank P Kroon, Laura van Zonneveld, Paul H P Groeneveld, Marjolein van Broekhuizen, Silvia M A A Evers, Jan M Prins
BACKGROUND: No high-quality trials have provided evidence of effectiveness and cost-effectiveness of HIV treatment adherence intervention strategies. We therefore examined the effectiveness and cost-effectiveness of the Adherence Improving self-Management Strategy (AIMS) compared with treatment as usual. METHODS: We did a pragmatic, multicentre, open-label, randomised controlled trial in seven HIV clinics at academic and non-academic hospitals in the Netherlands...
March 2, 2017: Lancet Infectious Diseases
https://www.readbyqxmd.com/read/28261580/a-blueprint-to-evaluate-one-health
#18
Simon R Rüegg, Barry J McMahon, Barbara Häsler, Roberto Esposito, Liza Rosenbaum Nielsen, Chinwe Ifejika Speranza, Timothy Ehlinger, Marisa Peyre, Maurizio Aragrande, Jakob Zinsstag, Philip Davies, Andrei Daniel Mihalca, Sandra C Buttigieg, Jonathan Rushton, Luís P Carmo, Daniele De Meneghi, Massimo Canali, Maria E Filippitzi, Flavie Luce Goutard, Vlatko Ilieski, Dragan Milićević, Helen O'Shea, Miroslav Radeski, Richard Kock, Anthony Staines, Ann Lindberg
One Health (OH) positions health professionals as agents for change and provides a platform to manage determinants of health that are often not comprehensively captured in medicine or public health alone. However, due to the organization of societies and disciplines, and the sectoral allocation of resources, the development of transdisciplinary approaches requires effort and perseverance. Therefore, there is a need to provide evidence on the added value of OH for governments, researchers, funding bodies, and stakeholders...
2017: Frontiers in Public Health
https://www.readbyqxmd.com/read/28259853/effectiveness-of-a-cough-management-algorithm-at-the-transitional-phase-from-acute-to-chronic-cough-in-australian-children-aged-15%C3%A2-years-protocol-for-a-randomised-controlled-trial
#19
Kerry-Ann F O'Grady, Keith Grimwood, Maree Toombs, Theo P Sloots, Michael Otim, David Whiley, Jennie Anderson, Sheree Rablin, Paul J Torzillo, Helen Buntain, Anne Connor, Don Adsett, Oon Meng Kar, Anne B Chang
INTRODUCTION: Acute respiratory infections (ARIs) are leading causes of hospitalisation in Australian children and, if recurrent, are associated with increased risk of chronic pulmonary disorders later in life. Chronic (>4 weeks) cough in children following ARI is associated with decreased quality-of-life scores and increased health and societal economic costs. We will determine whether a validated evidence-based cough algorithm, initiated when chronic cough is first diagnosed after presentation with ARI, improves clinical outcomes in children compared with usual care...
March 3, 2017: BMJ Open
https://www.readbyqxmd.com/read/28258420/gender-related-differences-in-the-multi-pathway-effect-of-social-determinants-on-quality-of-life-in-older-age-the-courage-in-europe-project
#20
Beata Tobiasz-Adamczyk, Aleksander Galas, Katarzyna Zawisza, Somnath Chatterji, Josep Maria Haro, José Luis Ayuso-Mateos, Seppo Koskinen, Matilde Leonardi
PURPOSE: Gender-related differences in life expectancy, prevalence of chronic conditions and level of disability in the process of ageing have been broadly described. Less is known about social determinants, which may have different impacts on quality of life in men and women. The investigation aims to reveal gender-related differences in social determinants on quality of life assessed by a multi-pathway model including health, social, demographic and living place characteristics. METHODS: The study group consisted of 5099 participants aged 50+ representing general populations of three different European regions (Finland, Poland, Spain) who participated in COURAGE in EUROPE Project...
March 3, 2017: Quality of Life Research
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