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https://www.readbyqxmd.com/read/29781834/ocular-findings-in-exfoliation-syndrome
#1
Robert Ritch
Exfoliation syndrome (XFS) is characterized by numerous ocular manifestations, the most important of these being glaucoma and cataract. Its ocular manifestations affect all of the structures of the anterior segment as well as conjunctiva and orbital structures. Exfoliation material is seen most prominently as characteristic white deposits on the anterior surface of the lens and the pupillary border of the iris. Both open-angle and angle-closure glaucoma are intimately associated with XFS. Other findings include zonular disruption, iris sphincter fibrosis, keratopathy, ocular surface disease, and retinal vein occlusion...
May 17, 2018: Journal of Glaucoma
https://www.readbyqxmd.com/read/29776684/a-hybrid-technique-to-address-exposure-keratopathy-secondary-to-facial-nerve-paresis-a-combination-of-a-lateral-tarsorrhaphy-and-lateral-wedge-resection
#2
Roxana Fu, Nicholas Moore, Taha Z Shipchandler, Jonathan Y Ting, Travis Tollefson, Cyrus Rabbani, Meena Moorthy, William R Nunery, H B Harold Lee
PURPOSE: To present the results of treating combined lower eyelid laxity, retraction and midface descent secondary to facial nerve weakness with a hybrid surgical procedure. MATERIALS AND METHODS: A retrospective analysis of patients from January 2015 to January 2017 who underwent a hybrid surgical technique for the treatment of corneal exposure secondary to facial nerve paresis with a single surgeon was performed. Age, gender, and presence of exposure symptoms were recorded pre-operatively...
May 9, 2018: American Journal of Otolaryngology
https://www.readbyqxmd.com/read/29774172/moebius-syndrome-with-hypoglossal-palsy-syndactyly-brachydactyly-and-anisometropic-amblyopia
#3
Muhammad Hassaan Ali, Samreen Jamal, Muhammad Ather Rashid, Usman Javaid, Nadeem Hafeez Butt
Moebius syndrome is a rare cause of congenital facial and abducens palsy.  It is sometimes associated with musculoskeletal abnormalities and other cranial nerve palsies. Genetics and ischemic insults to the fetus are considered to be the cause of this syndrome. We report here a 12-year-old female patient who was presented to us with poor cosmesis of her face, with associated decreased vision and lagophthalmos in her left eye. She didn't have any signs of exposure keratopathy in the affected eye. Her best-corrected vision was 20/20 and 20/60 in right and left eyes respectively...
March 16, 2018: Curēus
https://www.readbyqxmd.com/read/29773271/juvenile-idiopathic-arthritis-associated-uveitis
#4
REVIEW
Ethan S Sen, A V Ramanan
Juvenile idiopathic arthritis (JIA) is the commonest rheumatic disease in children and JIA-associated uveitis its most frequent extra-articular manifestation. The uveitis is potentially sight-threatening and thus carries a considerable risk of morbidity with associated reduction in quality of life. The commonest form of uveitis seen in association with JIA is chronic anterior uveitis, which is almost always asymptomatic in the initial stages. Therefore, screening for JIA-associated uveitis in at-risk patients is essential...
August 2017: Best Practice & Research. Clinical Rheumatology
https://www.readbyqxmd.com/read/29766356/endothelial-cell-loss-and-graft-survival-after-penetrating-keratoplasty-for-laser-iridotomy-induced-bullous-keratopathy
#5
Naoki Okumura, Ayaka Kusakabe, Noriko Koizumi, Koichi Wakimasu, Kanae Kayukawa, Masami Kondo, Kazuhiko Mori, Chie Sotozono, Shigeru Kinoshita
PURPOSE: To assess corneal endothelial cell loss after penetrating keratoplasty (PK) treatment for laser iridotomy (LI)-induced bullous keratopathy (BK). METHODS: A retrospective study conducted on consecutive patients who underwent PK between March 2000 and December 2011. Patients who had undergone more than 24 months of follow-up were included. Patients who underwent PK were subcategorized into two groups based on their diagnosis of BK prior to PK; PK was performed to treat either LI-BK or non LI-BK...
May 15, 2018: Japanese Journal of Ophthalmology
https://www.readbyqxmd.com/read/29765780/outcomes-and-complications-of-scleral-fixated-intraocular-lens-combined-with-ahmed-tube-surgery
#6
Nikhel Sachdev, Maria Cecilia Aquino, Seng Chee Loon, Yiong Huak Chan, Paul Chew, Victor Koh
Background: To evaluate the outcome and complications of transscleral suture-fixated posterior chamber intraocular lens (PCIOL) implantation combined with Ahmed glaucoma valve (AGV) surgery in Asian eyes. Design: This was a retrospective study that included 22 eyes from 22 participants. The surgeries were performed at Singapore's National University Hospital. Participants underwent an Ahmed tube surgery, together with transscleral suture-fixated posterior chamber intraocular lens...
2018: Journal of Ophthalmology
https://www.readbyqxmd.com/read/29755905/a-case-of-neurotrophic-keratopathy-concomitant-to-brain-metastasis
#7
Chiara Bonzano, Elisabetta Bonzano, Carlo Alberto Cutolo, Riccardo Scotto, Carlo Enrico Traverso
We report a case of a 63-year-old Caucasian female referred to the cornea service of Clinica Oculistica with a neurotrophic corneal ulcer, decreased corneal sensitivity, absent corneal reflex, and decreased lacrimation. The medical record review was relevant for mastectomy and adjuvant therapy for breast cancer complicated by pontocerebellar angle metastasis. Eye patching and application of antibiotic and vitamin ointments were prescribed at first, without a significant improvement. Thus, treatment with autologous serum was started...
March 12, 2018: Curēus
https://www.readbyqxmd.com/read/29755822/descemet-membrane-endothelial-keratoplasty-with-irregular-edged-graft-a-salvage-method-for-large-radial-graft-tears
#8
Mehmet Cüneyt Özmen, Nilay Dilekmen, Erdem Yüksel, Bahri Aydın, Fikret Akata
Large radial tears of donor Descemet membrane (DM) during the preparation of Descemet membrane endothelial keratoplasty (DMEK) grafts can make the trephination stage impossible because of small graft diameter. This results in irregular-edged grafts. In this study, we report two pseudophakic bullous keratopathy patients who underwent DMEK surgery with irregular-edged Descemet membrane (DM) grafts. Main outcome measures were preoperative and postoperative 1-, 3-, and 6-month best corrected visual acuity (BCVA), endothelial cell density (ECD) and central corneal thickness (CCT)...
April 2018: Turkish Journal of Ophthalmology
https://www.readbyqxmd.com/read/29750121/-in-vivo-confocal-microscopic-observations-of-vortex-keratopathy-in-patients-with-amiodarone-induced-keratopathy-and-fabry-disease
#9
Yasuhito Ikegawa, Atsushi Shiraishi, Yasuhito Hayashi, Akiyoshi Ogimoto, Yuichi Ohashi
Purpose: To compare the morphology of two types of vortex keratopathy: amiodarone-induced keratopathy and the Fabry disease-associated keratopathy. Patients and Methods: Eight patients who were receiving oral amiodarone therapy and 3 patients with Fabry disease, a mother and her 2 daughters, were examined by slit-lamp biomicroscopy and in vivo confocal microscopy (IVCM) regularly. Results: Amiodarone-induced keratopathy developed in 7 of the 8 patients, and it was detected as early as 7 days by IVCM and 14 days by slit-lamp biomicroscopy...
2018: Journal of Ophthalmology
https://www.readbyqxmd.com/read/29708929/surgical-management-of-herpetic-keratitis
#10
Sonal Tuli, Matthew Gray, Ankit Shah
PURPOSE OF REVIEW: The purpose of this review is to discuss the options for, and recent developments in, the surgical treatment of herpes keratitis. Although the mainstay of treatment of herpetic keratitis is topical or oral antiviral agents, surgical intervention may be necessary for corneal melting or long-term complications such as scarring, lipid keratopathy, necrotizing keratitis, and neurotrophic keratitis. RECENT FINDINGS: There are a number of surgical therapies available for herpes keratitis...
April 27, 2018: Current Opinion in Ophthalmology
https://www.readbyqxmd.com/read/29698813/neuropathic-keratopathy
#11
REVIEW
Harminder S Dua, Dalia G Said, Elisabeth M Messmer, Maurizio Rolando, Jose M Benitez-Del-Castillo, Parwez N Hossain, Alex J Shortt, Gerd Gerling, Mario Nubile, Francisco C Figueiredo, Saaeha Rauz, Leonardo Mastropasqua, Paolo Rama, Christophe Baudouin
Neurotrophic Keratopathy (NK) refers to a condition where corneal epitheliopathy leading to frank epithelial defect with or without stromal ulceration (melting) is associated with reduced or absent corneal sensations. Sensory nerves serve nociceptor and trophic functions, which can be affected independently or simultaneously. Loss of trophic function and consequent epithelial breakdown exposes the stroma making it susceptible to enzymatic degradation. Nerve pathology can range from attrition to aberrant re-generation with corresponding symptoms from anaesthesia to hyperaesthesia/allodynia...
April 23, 2018: Progress in Retinal and Eye Research
https://www.readbyqxmd.com/read/29697353/graft-failure-and-repeat-penetrating-keratoplasty
#12
Ozlem Barut Selver, Irmak Karaca, Melis Palamar, Sait Egrilmez, Ayse Yagci
OBJECTIVES: In this study, we report the indications and outcomes of repeat penetrating keratoplasty and the reasons for graft failure. MATERIALS AND METHODS: We performed a retrospective data analysis of patients who had undergone 2 or more penetrating keratoplasties for the same eye between 1991 and 2016. RESULTS: Among 1613 penetrating keratoplasties, 149 regrafts of 105 eyes were reviewed. The mean follow-up time after repeat penetrating keratoplasty was 3...
April 26, 2018: Experimental and Clinical Transplantation
https://www.readbyqxmd.com/read/29692490/glued-intraocular-lens-with-descemet-stripping-endothelial-keratoplasty-in-aphakic-bullous-keratopathy
#13
Anita Mani, P S Moulick, Alok Sati, Sandeep Gupta
No abstract text is available yet for this article.
April 2018: Medical Journal, Armed Forces India
https://www.readbyqxmd.com/read/29682916/pediatric-uveitis
#14
Nicole Shu-Wen Chan, Jessy Choi, Chui Ming Gemmy Cheung
Pediatric uveitis differs from adult-onset uveitis and is a topic of special interest because of its diagnostic and therapeutic challenges. Children with uveitis are often asymptomatic and the uveitis is often chronic, persistent, recurrent, and resistant to conventional treatment. Anterior uveitis is the most common type of uveitis in children; the prevalence of intermediate, posterior, and panuveitis varies geographically and among ethnic groups. Regarding etiology, most cases of pediatric uveitis are idiopathic but can be due to systemic inflammatory disorders, infections, or a manifestation of masquerade syndrome...
April 23, 2018: Asia-Pacific Journal of Ophthalmology
https://www.readbyqxmd.com/read/29681843/wheel-spokes-technique-for-endothelial-keratoplasty-for-extremely-mydriatic-bullous-keratopathy-eyes-without-capsular-support
#15
Hidenori Tanaka, Koji Hirano, Masayuki Horiguchi
We describe a new technique to prevent an endothelial donor graft from dropping into the vitreous cavity during non-Descemet stripping automated endothelial keratoplasty (nDSAEK) for extremely mydriatic bullous keratopathy (BK) eyes without capsular support. The patient was a 79-year-old woman who underwent nDSAEK for an extremely mydriatic BK eye with an incomplete barrier between the anterior and posterior chambers. She had undergone argon laser iridotomy for acute glaucoma at the age of 59 years and cataract surgery 3 years later...
January 2018: Case Reports in Ophthalmology
https://www.readbyqxmd.com/read/29681179/-femtosecond-laser-assisted-keratoplasty
#16
László Módis, Eszter Szalai, Zsuzsanna Flaskó, Bence Kolozsvári, András Berta
INTRODUCTION AND AIM: To present our results on femtosecond laser-assisted penetrating keratoplasty. PATIENTS AND METHOD: Twenty-five eyes of 25 patients underwent surgery with the following indications: pseudophakic bullous keratopathy (n = 10), keratoconus (n = 4), corneal dystrophy (n = 5), corneal scar (n = 4), band keratopathy (n = 2). Trephination of both the donor and recipient corneas were performed with VisuMax femtosecond laser device (Carl Zeiss Meditec AG, Jena, Germany)...
April 2018: Orvosi Hetilap
https://www.readbyqxmd.com/read/29675350/postoperative-intraocular-lens-opacification
#17
Shang-Te Ma, Chung-May Yang, Yu-Chih Hou
Intraocular lens (IOL) opacification is rare but may occur after non-Descemet stripping automated endothelial keratoplasty (n-DSAEK) or intravitreal air injection after pars plana vitrectomy (PPV). We reported two cases of IOL opacification within the pupillary region. Chart was retrospectively reviewed. The predisposing factors and the visual acuity were analyzed. The opacification was evaluated by anterior segment optical coherence tomography (AS-OCT). A 68-year-old healthy woman with pseudophakic bullous keratopathy underwent uneventful n-DSAEK in the right eye...
January 2018: Taiwan Journal of Ophthalmology
https://www.readbyqxmd.com/read/29675348/clinical-histopathology-of-intrachoroidal-splitting-in-open-globe-injury-a-retrospective-case-series-of-four-patients
#18
Liang Han, Yen-Ling Cho, Zhizhong Ma, Xinrong Zhao, Xin Chang
PURPOSE: The purpose of this study is to observe the characteristics of intrachoroidal splitting (ICS) associated with choroidal detachment due to open-globe injury. METHODS: A retrospective, observational case series study of four eyes diagnosed with choroidal detachment exhibited ICS. The in vivo pathologic changes of the ICS were recorded during surgery. Four specimens were obtained from the inner part of the ICS region. One specimen was stained with hematoxylin and eosin; one specimen was examined under scanning electron microscopy, and the other two specimens were examined under transmission electron microscopy...
January 2018: Taiwan Journal of Ophthalmology
https://www.readbyqxmd.com/read/29671668/pediatric-primary-calcific-band-keratopathy-with-or-without-glaucoma-from-biallelic-slc4a4-mutations
#19
Arif O Khan, Omar S Basamh
Biallelic mutations in the gene SLC4A4 (Solute Carrier Family 4 Member 4) cause protean manifestations in children that include proximal retinal tubular acidosis, developmental delay, band keratopathy, and glaucoma. A unique SLC4A4 mutation causes an ocular-only phenotype. In this retrospective case series, we highlight our experience with children referred to a pediatric ophthalmologist who were found to harbor underlying biallelic SLC4A4 mutations.
April 19, 2018: Ophthalmic Genetics
https://www.readbyqxmd.com/read/29668572/atypical-presentation-of-iridocorneal-endothelial-syndrome-with-band-keratopathy-but-no-corneal-edema-managed-with-descemet-membrane-endothelial-keratoplasty
#20
Vasiliki Zygoura, Itay Lavy, Robert M Verdijk, Diana Santander-García, Lamis Baydoun, Isabel Dapena, Gerrit R J Melles
PURPOSE: To report an unusual presentation of iridocorneal endothelial (ICE) syndrome associated with band keratopathy and its management with ethylenediamine-tetraacetic acid (EDTA) chelation and Descemet membrane endothelial keratoplasty (DMEK). METHODS: A 57-year-old female patient presented with unilateral progressive painless visual impairment, corneal band keratopathy, and morphological corneal endothelial changes without corneal edema or any previous ophthalmic, medical, or family history...
April 17, 2018: Cornea
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