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https://www.readbyqxmd.com/read/27895364/a-10-year-review-of-indications-for-penetrating-keratoplasty-in-a-tertiary-care-setting-in-karachi-pakistan
#1
Tanveer Ajum Chaudhry, Salman Naveed Sadiq, Zubaida Sirang, Maheen Akhtar Syed, Mustafa Kamal, Khabir Ahmad
The retrospective study was conducted to determine the indications and outomes of penetrating keratoplasty(PKP) in a tertiary care setting in Pakistan. All eyes that had undergone PKP between January 2005 and December 2014 at the Aga Khan University Hospital, Karachi, were included.Data were collected on the indications of PKP, graft survival (graft clarity at final follow-up), andbest corrected visual acuity (BCVA).Kaplan-Meier\'s method was usedto analyse graft survival.Out of 437 eyes, 383(87%) were for visual purpose...
October 2016: JPMA. the Journal of the Pakistan Medical Association
https://www.readbyqxmd.com/read/27890620/drug-induced-corneal-epithelial-changes
#2
REVIEW
Michael B Raizman, Pedram Hamrah, Edward J Holland, Terry Kim, Francis S Mah, Christopher J Rapuano, Roger G Ulrich
Drugs across many pharmacologic classes induce corneal epithelial changes. Many of these drugs have cationic amphiphilic structures, with a hydrophobic ring and hydrophilic cationic amine side chain that allow them to cross cell membranes. These drugs lead to intracellular phospholipid accumulation, often manifested in the cornea by vortex keratopathy, with no effect on visual acuity and few ocular symptoms. Other drugs, notably antineoplastic agents, produce a fine diffuse corneal haze, sometimes accompanied by decreased vision that can be dose limiting...
November 24, 2016: Survey of Ophthalmology
https://www.readbyqxmd.com/read/27885526/twelve-year-follow-up-of-penetrating-keratoplasty
#3
Takashi Ono, Sosuke Ishiyama, Takeshi Hayashidera, Yosai Mori, Ryohei Nejima, Kazunori Miyata, Shiro Amano
PURPOSE: To evaluate the long-term outcomes of penetrating keratoplasty (PKP) according to the corneal disease diagnosis and the number of PKP procedures performed. METHODS: Five-hundred-and-nine eyes from 403 patients who underwent PKP at Miyata Eye Hospital in Japan from 1998 through 2014, were included in this study. Medical charts were retrospectively examined to ascertain the corneal disease diagnosis and the period of graft survival. Graft survival rates were compared among various corneal disease diagnoses and among the number of PKP procedures performed...
November 24, 2016: Japanese Journal of Ophthalmology
https://www.readbyqxmd.com/read/27873061/-opacification-of-a-hydrophilic-acrylic-intraocular-lens-after-dmek-a-material-analysis
#4
C Milojcic, C Latz, T Tandogan, G U Auffarth, F G Holz, C Y Choi, R Khoramnia
OBJECTIVE: Calcification of a hydrophilic intraocular lens (IOL) is a rare complication. We report on the analysis of an opacified IOL, which was explanted 2 years after Descemet membrane endothelial keratoplasty (DMEK), using light and scanning electron microscopy, X‑ray spectroscopy and investigations on the optical bench. METHODS: In October 2012 a patient with pseudophakic keratopathy and Fuchs endothelial dystrophy underwent DMEK with double rebubbling. Due to primary graft failure the patient underwent penetrating keratoplasty in January 2013...
November 21, 2016: Der Ophthalmologe: Zeitschrift der Deutschen Ophthalmologischen Gesellschaft
https://www.readbyqxmd.com/read/27843275/current-trends-in-treatment-outcomes-of-orbital-cellulitis-in-a-tertiary-hospital-in-southern-nigeria
#5
Odarosa M Uhumwangho, Dumebi H Kayoma
BACKGROUND: Orbital cellulitis refers to the inflammation or infection of the soft tissues of the orbit located behind the orbital septum. AIM: To determine the current trends in the outcomes following the management of orbital cellulitis in a tertiary hospital in Southern Nigeria. PATIENTS AND METHODS: A retrospective review of medical records of patients with orbital cellulitis from January 2008 to December 2014 was conducted. The age, sex, duration of symptoms, predisposing factors, clinical findings, laboratory/radiological investigations, treatment provided, complications, and follow-up were recorded...
July 2016: Nigerian Journal of Surgery: Official Publication of the Nigerian Surgical Research Society
https://www.readbyqxmd.com/read/27828915/trends-in-orbital-decompression-techniques-of-surveyed-american-society-of-ophthalmic-plastic-and-reconstructive-surgery-members
#6
Shani S Reich, Robert C Null, Peter J Timoney, Jason A Sokol
PURPOSE: To assess current members of the American Society of Ophthalmic Plastic and Reconstructive Surgery (ASOPRS) regarding preference in surgical techniques for orbital decompression in Graves' disease. METHODS: A 10-question web-based, anonymous survey was distributed to oculoplastic surgeons utilizing the ASOPRS listserv. The questions addressed the number of years of experience performing orbital decompression surgery, preferred surgical techniques, and whether orbital decompression was performed in collaboration with an ENT surgeon...
November 2016: Ophthalmic Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/27828913/long-term-results-of-total-retinectomy-in-cases-with-advanced-proliferative-vitreoretinopathy
#7
Murat Karacorlu, Isil Sayman Muslubas, Mumin Hocaoglu, Serra Arf, Mehmet Giray Ersoz
PURPOSE: To evaluate the long-term results of total retinectomy in patients with rhegmatogenous retinal detachment and severe proliferative vitreoretinopathy. METHODS: Seven eyes of 7 patients had pars plana vitrectomy, with or without pars plana lensectomy, and total retinectomy, with or without silicone oil tamponade, for the management of rhegmatogenous retinal detachment and proliferative vitreoretinopathy (Grade D1-3) after previous complex vitreoretinal surgery procedures...
November 8, 2016: Retina
https://www.readbyqxmd.com/read/27820951/elevated-cytokine-levels-in-the-aqueous-humor-of-eyes-with-bullous-keratopathy-and-low-endothelial-cell-density
#8
Takefumi Yamaguchi, Kazunari Higa, Terumasa Suzuki, Naohiko Nakayama, Yukari Yagi-Yaguchi, Murat Dogru, Yoshiyuki Satake, Jun Shimazaki
Purpose: To evaluate cytokine levels in the aqueous humor (AqH) of eyes with bullous keratopathy (BK) and low endothelial cell density (ECD). Methods: A total of 145 AqH samples (60 BK, 16 low ECD, 35 corneal diseases with normal ECD, and 34 normal controls) were collected from consecutive patients who underwent corneal transplantation or cataract surgery. None of the patients had any clinically apparent inflammation at the time of AqH collection. The AqH levels of cytokines (IL-1α, IL-1β, IL-2, IL-4, IL-6, IL-8, IL-10, IL-12p70, IL-13, IL-17A, IFN-α, IFN-γ, monocyte chemotactic protein [MCP]-1, TNF-α, E-selectin, P-selectin, soluble intercellular adhesion molecule [sICAM]-1, granulocyte-macrophage colony-stimulating factor [GM-CSF], macrophage inflammatory protein [MIP] -1α and MIP-1β) were compared among the groups...
November 1, 2016: Investigative Ophthalmology & Visual Science
https://www.readbyqxmd.com/read/27819784/-prognostic-category-of-corneal-transplantation-in-a-referal-center
#9
Karla Verdiguel-Sotelo, Arturo Carrasco-Quiroz, Josué Rangel-Servín
BACKGROUND: Penetrating keratoplasty is considered the most frequent and successfully performed organ transplantation. Indications of corneal transplantation have changed over time and they vary according to the country. Some risk factors for graft rejection, as age, corneal vascularization or ocular surgery, among others, have been identified. The aim was to identify the prognostic category, group and associated risk factors of patients registered in the database of corneal transplantation in the Centro Médico Nacional La Raza between 2011 and 2013...
November 2016: Revista Médica del Instituto Mexicano del Seguro Social
https://www.readbyqxmd.com/read/27805532/visual-rehabilitation-after-penetrating-keratoplasty
#10
Leyla Asena, Dilek D Altınörs
OBJECTIVES: Here, our aim was to report our treatment strategies and their results performed for visual rehabilitation after penetrating keratoplasty. MATERIALS AND METHODS: The medical records of 98 patients (54 male/44 female), with results from 104 eyes, who underwent penetrating keratoplasty between January 2013 and January 2015 at the Baskent University Faculty of Medicine, Department of Ophthalmology were reviewed. Patient age, indication for penetrating keratoplasty, interventions performed for visual rehabilitation, follow-up duration, topographic and refractive astigmatism at the end of follow-up, and final best corrected visual acuity results were recorded...
November 2016: Experimental and Clinical Transplantation
https://www.readbyqxmd.com/read/27800249/clinical-findings-follow-up-and-treatment-results-in-patients-with-ocular-rosacea
#11
İlkay Kılıç Müftüoğlu, Yonca Aydın Akova
OBJECTIVES: To report the clinical features, treatment options and complications in patients with ocular rosacea. MATERIALS AND METHODS: The records of 48 eyes of 24 patients with ocular rosacea were retrospectively reviewed. Patients' ocular signs and symptoms were scored between 1 and 4 points according to disease severity; tear film break-up time (BUT) and Schirmer's test results were recorded before and after the treatment. Preservative-free artificial tears, topical antibiotic eye drops/ointments, short-term topical corticosteroids, topical 0...
January 2016: Turkish Journal of Ophthalmology
https://www.readbyqxmd.com/read/27799829/bleb-incarceration-following-ahmed-valve-surgery
#12
Fredric J Gross, Giovanni DiSandro
Globe luxation is a painful and potentially vision-threatening condition in which the globe becomes trapped behind the eyelids requiring physician intervention in the emergency department or eye clinic. On presentation, the patient typically complains of an inability to close their eye, severe foreign body sensation, decreased vision, and significant eye pain. Although most visual symptoms are reversible and primarily result from exposure keratopathy, optic nerve damage, and permanent vision loss can occur from repeat or prolonged episodes of globe luxation...
2016: International Medical Case Reports Journal
https://www.readbyqxmd.com/read/27793489/eyelid-lymphoma-in-a-patient-with-a-gold-weight-implant
#13
L A Di Nisio, J O Croxatto, M C Mansur, J P Aldecoa, D Weil
CASE REPORT: A male patient with an exposure keratopathy caused by lagophthalmos. A gold weight was implanted in the right upper eyelid. Eight months later, he presented with erythema and swelling of right upper eyelid. An incisional biopsy was performed, reporting extranodal marginal zone B cell lymphoma. DISCUSSION: when a tumour at the site of a gold weight implant is refractory to treatment, it is essential to perform an incisional biopsy to establish the histopathological diagnosis...
October 25, 2016: Archivos de la Sociedad Española de Oftalmología
https://www.readbyqxmd.com/read/27771327/in-vivo-confocal-microscopy-of-corneal-nerves-in-health-and-disease
#14
Andrea Cruzat, Yureeda Qazi, Pedram Hamrah
In vivo confocal microscopy (IVCM) is becoming an indispensable tool for studying corneal physiology and disease. Enabling the dissection of corneal architecture at a cellular level, this technique offers fast and noninvasive in vivo imaging of the cornea with images comparable to that of ex vivo histochemical techniques. Corneal nerves bear substantial relevance to clinicians and scientists alike, given their pivotal roles in regulation of corneal sensation, maintenance of epithelial integrity, and proliferation and promotion of wound healing...
October 19, 2016: Ocular Surface
https://www.readbyqxmd.com/read/27766386/-botulinum-toxin-a%C3%A2-induced-protective-ptosis-for-the-treatment-of-recurrent-epithelial-defects-in-neurotrophic-keratopathy
#15
A Schilimow, B Wiechens
In this article, a case of recurrent epithelial defects in neurotrophic keratopathy is described. Multiple abrasions of the corneal epithelium with a therapeutic contact lens, corneal stitches, and amniotic membrane transplantation in combination with artificial tears brought only short-term success. However, a botulinum toxin A induced protective ptosis could finally achieve permanent epithelial closure. As this case shows, protective ptosis can be a promising approach in spite of multiple previous ineffective therapeutic efforts...
October 20, 2016: Der Ophthalmologe: Zeitschrift der Deutschen Ophthalmologischen Gesellschaft
https://www.readbyqxmd.com/read/27740620/in-vivo-confocal-microscopy-of-toxic-keratopathy
#16
Y Chen, Q Le, J Hong, L Gong, J Xu
PurposeTo explore the morphological characteristics of toxic keratopathy (TK), which clinically presented as superficial punctate keratopathy (SPK), with the application of in vivo laser-scanning confocal microscopy (LSCM), and evaluate its potential in the early diagnosis of TK.Patients and methodsThis was a cross-sectional study involving 16 patients with TK and 16 patients with dry eye (DE), demonstrating SPK under slit-lamp observation, and 10 normal eyes were enrolled in the study. All participants underwent history interviews, fluorescein staining, tear film break-up time (BUT) tests, Schirmer tests, and in vivo LSCM...
October 14, 2016: Eye
https://www.readbyqxmd.com/read/27729751/the-change-of-lacrimal-gland-volume-in-korean-patients-with-thyroid-associated-ophthalmopathy
#17
Hyoun-Do Huh, Ji-Hye Kim, Seong-Jae Kim, Ji-Myong Yoo, Seong-Wook Seo
PURPOSE: To describe the change of lacrimal gland volumes in Korean patients with thyroid-associated ophthalmopathy (TAO) via computed tomography (CT). METHODS: A retrospective review of CT images from 217 TAO patients and 135 control subjects was performed. The TAO patients were diagnosed between May 2005 and May 2014 and had a CT performed on initial presentation (330 orbital CT scans). These images were compared with 270 orbital CT scans from the control group, obtained between May 2013 and May 2014...
October 2016: Korean Journal of Ophthalmology: KJO
https://www.readbyqxmd.com/read/27724848/morphological-changes-in-the-meibomian-glands-of-patients-with-phlyctenular-keratitis-a-multicenter-cross-sectional-study
#18
Takashi Suzuki, Naoyuki Morishige, Reiko Arita, Shizuka Koh, Tohru Sakimoto, Rika Shirakawa, Kazunori Miyata, Yuichi Ohashi
BACKGROUND: Phlyctenular keratitis is a hypersensitivity reaction of the cornea, and a complication of eyelid margin disease in children and young adults. In this study, we compared the morphology of the meibomian glands in eyelids between phlyctenular keratitis patients and healthy young adults, using noncontact meibography. METHODS: The study included 16 eyes of 13 patients diagnosed with phlyctenular keratitis and 17 eyes of 17 healthy volunteers. Slit-lamp observations of the cornea and eyelid were performed on all subjects...
October 10, 2016: BMC Ophthalmology
https://www.readbyqxmd.com/read/27696756/anti-il6-r-tocilizumab-for-severe-juvenile-idiopathic-arthritis-associated-uveitis-refractory-to-anti-tnf-therapy-a-multicenter-study-of-25-patients
#19
Vanesa Calvo-Río, Montserrat Santos-Gómez, Inmaculada Calvo, Ma Isabel González-Fernández, Berta López Montesinos, Marina Mesquida, Alfredo Adán, María Victoria Hernández, Olga Maíz, Antonio Atanes, Beatriz Bravo, Consuelo Modesto, Gisela Díaz-Cordovés, Natalia Palmou-Fontana, Javier Loricera, M C González-Vela, Rosalía Demetrio-Pablo, J L Hernández, Miguel A González-Gay, Ricardo Blanco
OBJECTIVE: To assess the efficacy of Tocilizumab (TCZ) for Juvenile Idiopathic Arthritis (JIA)-associated uveitis. METHODS: Multicenter study of patients with JIA-associated uveitis refractory to conventional immunosuppressive drugs and anti-TNFα agents. RESULTS: We assessed 25 (21 women) patients (47 affected eyes); mean age 18.5±8.3 years. Uveitis was bilateral in 22. Cystoid macular edema (CME) was present in 9 patients. Ocular sequelae found at TCZ onset included: cataracts (13), glaucoma (7), synechiae (10), band keratopathy (12), maculopathy (9), and amblyopia (5)...
October 1, 2016: Arthritis & Rheumatology
https://www.readbyqxmd.com/read/27668496/five-year-prose-treatment-for-aniridic-keratopathy
#20
Takashi Kojima, Asato Hasegawa, Tomoaki Nakamura, Naoki Isogai, Takahiro Kataoka, Kazuo Ichikawa
PURPOSE: Aniridic keratopathy is vision-threatening condition in patients with aniridia. The keratopathy occurs due to limbal stem cell deficiency. When conventional treatments fail, surgical treatments such as corneal limbal transplantation or cultivated oral mucosal epithelium transplantation are the alternatives. Here, we report our experience with the management and monitoring of the progress of a case with aniridic keratopathy treated with a scleral lens. CASE REPORT: We describe the case of a 30-year-old woman with aniridic keratopathy in both eyes...
October 2016: Optometry and Vision Science: Official Publication of the American Academy of Optometry
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