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https://www.readbyqxmd.com/read/29143927/update-on-the-treatment-of-uveitis-in-patients-with-juvenile-idiopathic-arthritis-a-review
#1
REVIEW
Ioannis Asproudis, Andreas Katsanos, Nikolaos Kozeis, Alexandra Tantou, Anastasios G Konstas
Chronic uveitis is a common extra-articular manifestation of juvenile idiopathic arthritis. The classic clinical picture is one of chronic anterior uveitis, which usually remains asymptomatic until ocular complications arise. The risk of uveitis is increased in girls with an early onset of oligoarthritis and positive antinuclear antibodies. Even though the inflammation in patients with juvenile idiopathic arthritis is initially limited in the anterior part of the eye, chronic active inflammation may eventually cause significant damage to the posterior pole...
November 16, 2017: Advances in Therapy
https://www.readbyqxmd.com/read/29137083/indications-and-outcomes-of-pediatric-keratoplasty-in-a-tertiary-eye-care-center-a-retrospective-review
#2
Rosario Gulias-Cañizo, Roberto Gonzalez-Salinas, Luis Fernando Hernandez-Zimbron, Everardo Hernandez-Quintela, Valeria Sanchez-Huerta
To evaluate indications and outcomes of pediatric keratoplasty in a tertiary eye center, and identify factors that affect visual outcomes.We performed a retrospective review of penetrating keratoplasty in children aged 0 to 18 years between 1995 and 2011 in the Asociación para Evitar la Ceguera en México IAP, Hospital "Dr. Luis Sánchez Bulnes".A total of 574 penetrating keratoplasties were performed during the study interval. Median follow-up was 5.0 years. Main indications included keratoconus (55.58%), postherpetic scarring (9...
November 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29133179/stage-related-central-corneal-epithelial-transformation-in-congenital-aniridia-associated-keratopathy
#3
Neil Lagali, Bogumil Wowra, Dariusz Dobrowolski, Tor Paaske Utheim, Per Fagerholm, Edward Wylegala
PURPOSE: To relate central corneal epithelial phenotype to degree of keratopathy in a limbal stem cell deficient population. METHODS: 37 patients (67 eyes) with aniridia-associated keratopathy (AAK) underwent corneal examination including slit lamp biomicroscopy to determine the Grade of AAK, Cochet-Bonnet esthesiometry, and in vivo confocal microscopy (IVCM) to assess morphology of the central corneal epithelium and subepithelial region. RESULTS: AAK Grade ranged from 1 (limbal involvement only) to 4 (total conjunctivalisation), with progression from Grade 1 occurring after the age of 20...
November 10, 2017: Ocular Surface
https://www.readbyqxmd.com/read/29132691/-practical-assessment-of-dsaek-in-the-management-of-endothelial-decompensation-following-penetrating-keratoplasty
#4
E Neiter, C Goetz, F Tortuyaux, A Ehrhardt, N Houmad, J-M Perone
PURPOSE: To report our anatomical and functional results as well as possible complications of the first six Descemet's stripping endothelial keratoplasties (DSAEK) performed in our department for endothelial decompensation after penetrating keratoplasty (PK) METHODS: This was a retrospective and observational monocentric study of six patients with DSAEK after prior PK between January 2015 and July 2016. The data collected were: demographic characteristics (age, sex), ophthalmological comorbidities, initial indication for PK, delay between PK and DSAEK...
November 11, 2017: Journal Français D'ophtalmologie
https://www.readbyqxmd.com/read/29119070/superior-ophthalmic-vein-access-for-embolization-of-an-indirect-carotid-cavernous-fistula
#5
Ali S Haider, Prabhat Garg, Dean Leonard, Tijani Osumah, Umair Khan, Steven Vayalumkal, Lyndon K Lee, Phu Nguyen, Grant Gilliland, Kennith F Layton
Carotid cavernous fistulae (CCF) are defined as abnormal connections between the carotid circulation and cavernous sinus. CCFs can be categorized as being direct or indirect. Direct CCFs are usually associated with trauma, whereas indirect CCFs are associated with revascularization following cavernous sinus thrombosis. We present a case of a 53-year-old male who presented with tinnitus, proptosis, conjunctivitis, and blurry vision. The patient had a recent endovascular transvenous embolization that was only partially successful, with a residual carotid cavernous fistula draining to the left superior ophthalmic vein and multiple cortical veins...
September 1, 2017: Curēus
https://www.readbyqxmd.com/read/29118495/emergency-visits-after-corneal-transplantation-in-yemen
#6
Mahfouth Abdalla Bamashmus, Saleh A Al-Akily, Hisham A AlAkhalee, Khaldoon O Al-Nuseriy, Marwan H Farhan
PURPOSE: Awareness of symptoms and signs of possible complications after corneal transplantation is very important. Early presentation can enhance long-term survival of the cornea. This study evaluates the reasons for emergency presentation and management of postcorneal transplantation complications. PATIENTS AND METHODS: This retrospective study included a total of 134 postkeratoplasty patients at the cornea unit in Yemen Magrabi Eye Hospital in Sana'a between 2008 and 2010...
September 2017: Oman Journal of Ophthalmology
https://www.readbyqxmd.com/read/29107724/prosthetic-replacement-of-the-ocular-surface-ecosystem-prose-treatment-of-ocular-surface-disease-following-skull-base-tumor-resection
#7
Carolyn E Kloek, Karen W Jeng-Miller, Deborah S Jacobs, Ian F Dunn
Prosthetic Replacement of the Ocular Surface Ecosystem (PROSE) treatment is an effective, non-surgical therapeutic option for patients with ocular surface disease related to cranial nerve deficits secondary to skull base tumor resection. This case series describes the impact of PROSE treatment in patients with symptomatic exposure keratopathy or neurotrophic keratitis after skull base tumor surgery. All patients improved symptomatically and functionally with PROSE treatment, and have had sustained improvement for as long as 3 years...
October 28, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/29101724/adjunctive-role-of-self-retained-cryopreserved-amniotic-membrane-in-treating-immune-related-dry-eye-disease
#8
Anny M S Cheng, Sean Tighe, Hosam Sheha, Scheffer C G Tseng
PURPOSE: To present a case of successful treatment of immune-related severe dry eye disease (DED) by self-retained cryopreserved amniotic membrane (CAM) in conjunction with conventional and systemic immunotherapy. OBSERVATIONS: A 48-year-old female with a 10-year history of rheumatoid arthritis under systemic immunomodulation developed non-resolved severe ocular dryness, pain, photophobia and blurred vision due to corneal epithelial keratopathy OD much worse than OS despite topical artificial tears, steroids, cyclosporine, autologous serum drops, punctal plugs and scleral lens for the last 3 years...
November 3, 2017: International Ophthalmology
https://www.readbyqxmd.com/read/29101006/corneal-abnormalities-in-congenital-aniridia-congenital-central-corneal-opacity-vs-aniridia-associated-keratopathy
#9
Hyo Kyung Lee, Mee Kum Kim, Joo Youn Oh
PURPOSE: To clinically characterize and compare two types of corneal abnormalities in patients with congenital aniridia: 1) congenital central corneal opacity from birth (CCO) and 2) aniridia-associated keratopathy (AAK) that develops progressively with age. DESIGN: Retrospective cohort study. METHODS: Medical records of Korean patients who were diagnosed with congenital aniridia at Seoul National University Hospital between 1991 and 2016 were reviewed...
October 31, 2017: American Journal of Ophthalmology
https://www.readbyqxmd.com/read/29097211/infectious-crystalline-keratopathy
#10
REVIEW
Ashley J Porter, Graham A Lee, Albert S Jun
Infectious crystalline keratopathy (ICK) was first reported by Gorovoy et al in 1983 when they identified bacteria colonizing a cornea after a penetrating keratoplasty. Subsequent cases have elaborated on the organisms responsible and the management outcomes. Patients present with a white or grey branching opacity originating from an epithelial defect, commonly after a penetrating keratoplasty. Local immunosuppression contributes to the quiescent nature and the limited inflammatory response associated with ICK...
October 30, 2017: Survey of Ophthalmology
https://www.readbyqxmd.com/read/29089772/isolated-descemetorhexis-for-anterior-synechiolysis-prior-to-endothelial-keratoplasty-case-report-and-technique
#11
Konstantinos Droutsas, Konstantinos Andreanos, Apostolos Lazaridis, Ilias Georgalas, George Kymionis, Dimitris Papaconstantinou
PURPOSE: To describe the utilization of descemetorhexis for reformation of the anterior chamber in eyes with central iridocorneal synechiae before endothelial keratoplasty (EK). METHODS: A 71-year-old man with a history of trabeculectomy complicated by hypotony presented with bullous keratopathy in the presence of extensive iridocorneal synechiae and a flat anterior chamber. In order to proceed with EK, synechiolysis with the use of viscoelastic and scissors was attempted...
2017: Therapeutics and Clinical Risk Management
https://www.readbyqxmd.com/read/29074873/regulatory-compliant-tissue-engineered-human-corneal-endothelial-grafts-restore-corneal-function-of-rabbits-with-bullous-keratopathy
#12
Gary S L Peh, Heng-Pei Ang, Chan N Lwin, Khadijah Adnan, Benjamin L George, Xin-Yi Seah, Shu-Jun Lin, Maninder Bhogal, Yu-Chi Liu, Donald T Tan, Jodhbir S Mehta
Corneal transplantation is the only treatment available to restore vision for individuals with blindness due to corneal endothelial dysfunction. However, severe shortage of available donor corneas remains a global challenge. Functional regulatory compliant tissue-engineered corneal endothelial graft substitute can alleviate this reliance on cadaveric corneal graft material. Here, isolated primary human corneal endothelial cells (CEnCs) propagated using a dual media approach refined towards regulatory compliance showed expression of markers indicative of the human corneal endothelium, and can be tissue-engineered onto thin corneal stromal carriers...
October 26, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29069709/ptosis-surgery-in-patients-with-myasthenia-gravis-a-useful-adjunct-to-medical-therapy
#13
Kerr Brogan, Maria E Farrugia, Kevin Crofts
INTRODUCTION: Medical management can have limitations in improving ptosis in patients with myasthenia gravis (MG). We present our experience of ptosis surgery in MG. MATERIALS AND METHODS: Clinical records of all patients with MG undergoing ptosis surgery from September 2007 to November 2013 in a single center were retrospectively reviewed. Change in upper marginal reflex distance (uMRD) was the main outcome measure. RESULTS: Sixteen external levator advancement (ELA) procedures were performed on 11 MG patients...
February 22, 2017: Seminars in Ophthalmology
https://www.readbyqxmd.com/read/29053558/in-vivo-confocal-microscopy-reveals-corneal-reinnervation-after-treatment-of-neurotrophic-keratopathy-with-corneal-neurotization
#14
Simon S M Fung, Joseph Catapano, Uri Elbaz, Ronald M Zuker, Gregory H Borschel, Asim Ali
PURPOSE: To document the presence and location of new sensory nerve fibers after corneal neurotization using in vivo confocal microscopy (IVCM) in 2 patients with neurotrophic keratopathy (NK). METHODS: Two patients with unilateral advanced NK received corneal neurotization to surgically reinnervate the cornea. IVCM was used to identify subbasal nerve fibers and document corneal reinnervation. In 1 patient (case 1), IVCM was performed before and after corneal neurotization; in the second patient (case 2), IVCM was performed after neurotization and corneal transplantation...
October 17, 2017: Cornea
https://www.readbyqxmd.com/read/29051590/association-between-corneal-endothelial-cell-densities-and-elevated-cytokine-levels-in-the-aqueous-humor
#15
Yukari Yagi-Yaguchi, Takefumi Yamaguchi, Kazunari Higa, Terumasa Suzuki, Naohiko Aketa, Murat Dogru, Yoshiyuki Satake, Jun Shimazaki
Annual reduction rate of corneal endothelial cell density (ECD) varies among etiologies, however, the cause of chronic endothelial cell loss is still unknown. We recently reported the elevation of inflammatory cytokines in the aqueous humor (AqH) in eyes with bullous keratopathy and low ECD. To evaluate the association between ECD and aqueous cytokine levels, we collected a total of 157 AqH samples prospectively. The AqH levels of cytokines were measured and multivariate analyses were conducted to find the correlation between ECD, aqueous cytokine levels and clinical factors, such as number of previous intraocular surgeries and protein concentration in AqH...
October 19, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29035922/effect-of-scattering-and-aberrations-on-visual-acuity-for-band-keratopathy
#16
Kazutaka Kamiya, Hidenaga Kobashi, Masahide Takahashi, Nobuyuki Shoji, Kimiya Shimizu
SIGNIFICANCE: The progressive accumulation of the calcification may deteriorate corneal transparency, especially in the interpalpebral area, and subsequent visual performance for patients with band keratopathy. However, the detailed quantitative analysis of light scattering or higher-order aberrations on visual performance for these patients so far has not been elucidated. PURPOSE: The aim of this study was to assess the relationship of intraocular forward scattering, corneal backward scattering, and corneal higher-order aberrations with visual acuity in eyes with band keratopathy...
November 2017: Optometry and Vision Science: Official Publication of the American Academy of Optometry
https://www.readbyqxmd.com/read/29034156/intraocular-lens-opacification-after-descemet-s-stripping-automated-endothelial-keratoplasty
#17
Meng-Sheng Lee, I-Lun Tsai, Ching-Yao Tsai, Li-Lin Kuo, Shiow-Wen Liou, Lin-Chung Woung
Compared with conventional penetrating keratoplasty, Descemet's stripping automated endothelial keratoplasty (DSAEK) more effectively maintain global integrity and rapid vision rehabilitation with less ocular surface disorders in patients with endothelial dysfunction. Here, we report a case of a 76-year-old woman who experienced opacification of a hydrophilic intraocular lens (IOL) approximately 10 months after DSAEK. The patient with no history of systemic disease developed pseudophakic bullous keratopathy in the right eye 2 years after undergoing cataract surgery...
July 2017: Taiwan Journal of Ophthalmology
https://www.readbyqxmd.com/read/29034153/efficacy-of-frontalis-suspension-with-silicone-rods-in-ptosis-patients-with-poor-bell-s-phenomenon
#18
Khyati P Shah, Bipasha Mukherjee
PURPOSE: The purpose of the study was to evaluate the efficacy of silicone rods as frontalis sling for correction of ptosis associated with poor Bell's phenomenon in specific situations. MATERIALS AND METHODS: A retrospective interventional case series of 25 eyes of 19 patients who underwent frontalis suspension surgery with silicone rods for ptosis correction from May 2006 to April 2011, was performed. Inclusion criteria included severe ptosis with poor Bell's phenomenon...
July 2017: Taiwan Journal of Ophthalmology
https://www.readbyqxmd.com/read/29033539/possible-association-between-subtypes-of-dry-eye-disease-and-seasonal-variation
#19
Masahiko Ayaki, Motoko Kawashima, Miki Uchino, Kazuo Tsubota, Kazuno Negishi
PURPOSE: The purpose of this study was to evaluate the influence of seasons on the signs and symptoms of dry eye disease (DED). METHODS: This is a cross-sectional, case-control study, and participants were non-DED subjects (n=1,916, mean age 54.4±14.4 years) and DED patients (n=684, 54.2±12.1 years) visiting six eye clinics at various practices and locations in Japan. We evaluated the signs and symptoms of DED and the seasons with the most severe results were compared to those with the least severe results in both groups...
2017: Clinical Ophthalmology
https://www.readbyqxmd.com/read/29029157/stings-of-the-ant-wasmannia-auropunctata-hymenoptera-formicidae-as-cause-of-punctate-corneal-lesions-in-humans-and-other-animals
#20
Diego Rosselli, James K Wetterer
Numerous researchers have observed a form of punctate corneal lesions causing leukomas (corneal opacities) in humans, domestic animals, and wild animals in different parts of the world. This condition has been reported under different names, including West Indian (or Caribbean) punctate keratopathy, West Indian dots, tropical punctate keratopathy, Rice's keratopathy, Florida keratopathy, and Florida spots. Many of these cases, appear to have a common cause, the stings of a small red ant, Wasmannia auropunctata (Hymenoptera: Formicidae), originally from the Neotropics, but spread to other parts of the world through human commerce...
November 7, 2017: Journal of Medical Entomology
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