keyword
MENU ▼
Read by QxMD icon Read
search

categorization

keyword
https://www.readbyqxmd.com/read/28545137/re-examining-the-association-between-residential-exposure-to-magnetic-fields-from-power-lines-and-childhood-asthma-in-the-danish-national-birth-cohort
#1
Madhuri Sudan, Onyebuchi A Arah, Thomas Becker, Yael Levy, Torben Sigsgaard, Jørn Olsen, Ximena Vergara, Leeka Kheifets
BACKGROUND: A study reported an increased risk of asthma in children whose mothers were exposed to magnetic field (MF) levels above 0.2 μT during pregnancy. We re-examined this association using data from mothers and children in the Danish National Birth Cohort (DNBC). METHODS: This study included 92,676 singleton-born children and their mothers from the DNBC. MF exposure from power lines was estimated for all residences where the mothers lived during pregnancy and for all children from birth until the end of follow up...
2017: PloS One
https://www.readbyqxmd.com/read/28545117/on-tests-of-treatment-covariate-interactions-an-illustration-of-appropriate-power-and-sample-size-calculations
#2
Gwowen Shieh
The appraisals of treatment-covariate interaction have theoretical and substantial implications in all scientific fields. Methodologically, the detection of interaction between categorical treatment levels and continuous covariate variables is analogous to the homogeneity of regression slopes test in the context of ANCOVA. A fundamental assumption of ANCOVA is that the regression slopes associating the response variable with the covariate variable are presumed constant across treatment groups. The validity of homogeneous regression slopes accordingly is the most essential concern in traditional ANCOVA and inevitably determines the practical usefulness of research findings...
2017: PloS One
https://www.readbyqxmd.com/read/28544941/time-based-expectations-entail-preparatory-motor-activity
#3
Gregor Volberg, Roland Thomaschke
Human behavior is guided by expectations that facilitate perception of upcoming events or reaction to them. In natural settings expectations are often implicitly based on time, e.g., when making a phone call one would expect to hear either a person answering (earlier) or a voicemail greeting (later). We investigated how time-based expectations can improve performance in the absence of explicit prior information on the pending stimulus or the associated response. Visual stimuli were presented after a characteristic short or long foreperiod, and a forced-choice categorization using either the left or the right hand was required...
May 4, 2017: Cortex; a Journal Devoted to the Study of the Nervous System and Behavior
https://www.readbyqxmd.com/read/28544923/unfavorable-prognostic-role-of-tumor-infiltrating-lymphocytes-in-hormone-receptor-positive-her2-negative-metastatic-breast-cancer-treated-with-metronomic-chemotherapy
#4
Emilia Montagna, Andrea Vingiani, Patrick Maisonneuve, Giuseppe Cancello, Federica Contaldo, Giancarlo Pruneri, Marco Colleoni
BACKGROUND: High levels of tumor-infiltrating lymphocytes (TILs) in primary triple negative and HER2-positive breast cancer (BC) have been associated with an improved patients' outcome. The role of TILs in Luminal (hormone receptor positive and HER2 negative) tumors remains to be elucidated. Moreover, the association between TILs and prognosis in the metastatic setting is still unknown. PATIENTS AND METHODS: We evaluated the relationship between TILs and time to progression (TTP) in metastatic BC patients enrolled in a prospective phase II trial of metronomic chemotherapy, that used cyclophosphamide 50 mg daily, capecitabine 500 mg thrice daily and vinorelbine 40 mg orally three times a week (VEX combination)...
May 22, 2017: Breast: Official Journal of the European Society of Mastology
https://www.readbyqxmd.com/read/28544825/leaflet-hypomobility-after-transcatheter-aortic-valve-replacement-thrombosis-or-mechanical-factors-a-possible-pathophysiological-pattern
#5
Michele Gallo, Stefanos Demertzis, Gino Gerosa, Enrico Ferrari
Transcatheter heart valve replacement is an emerging technology in the treatment of valvular disease. During recent years, the opportunity to replace a heart valve via percutaneous access or via a miniinvasive access without the use of cardiopulmonary bypass has revolutionized the approach to this pathology. The different designs of transcatheter valves have also altered the spectrum of possible complications, with the unexpected occurrence of leaflet hypomobility after valve deployment. Here, the pathophysiological pattern of this complication is categorized, and an analysis provided of recently reported clinical evidences...
January 2017: Journal of Heart Valve Disease
https://www.readbyqxmd.com/read/28544804/longitudinal-patterns-in-objective-physical-activity-and-sedentary-time-in-a-multi-ethnic-sample-of-children-from-the-uk
#6
L Smith, D Aggio, M Hamer
BACKGROUND: Children of South Asian decent born in the UK display lower levels of physical activity than British Caucasians although no longitudinal data are available. OBJECTIVES: We aimed to investigate change in activity levels over 1 year in a diverse ethnic sample of children residing in London, UK. METHODS: Children were categorized into ethnic groups (Caucasian/mixed, Black, South Asian). At baseline and 1-year follow-up, children's objective physical activity was monitored (Actigraph accelerometer) for at least 1 day...
May 22, 2017: Pediatric Obesity
https://www.readbyqxmd.com/read/28544776/comparison-of-histologic-margin-status-in-low-grade-cutaneous-and-subcutaneous-canine-mast-cell-tumours-examined-by-radial-and-tangential-sections
#7
C B Dores, M Milovancev, D S Russell
BACKGROUND: Radial sections are widely used to estimate adequacy of excision in canine cutaneous mast cell tumours (MCTs); however, this sectioning technique estimates only a small fraction of total margin circumference. This study aimed to compare histologic margin status in grade II/low grade MCTs sectioned using both radial and tangential sectioning techniques. MATERIALS AND METHODS: A total of 43 circumferential margins were evaluated from 21 different tumours...
May 23, 2017: Veterinary and Comparative Oncology
https://www.readbyqxmd.com/read/28544585/effects-of-ophthalmologic-solutions-on-sinonasal-ciliated-epithelium
#8
Alan D Workman, Ryan M Carey, Michael A Kohanski, Nithin D Adappa, James N Palmer, Noam A Cohen
BACKGROUND: Off-label use of topical ophthalmologic formulations for treatment of rhinologic disease is cited in recent literature and is anecdotally prevalent among practicing otolaryngologists. Steroids, antibiotics, and other drugs designed for ocular use have subjective clinical efficacy in the nose and sinuses, but their specific effects on the ciliated epithelium are less well defined. This study examines 9 commercially available ophthalmologic drug formulations for effects on ciliary motility in sinonasal cultures, in an effort to characterize their utility as topical therapies for sinonasal diseases...
May 23, 2017: International Forum of Allergy & Rhinology
https://www.readbyqxmd.com/read/28544540/serum-adrenomedullin-and-urinary-thromboxane-b2-help-early-categorizing-acute-kidney-injury-in-de-compensated-cirrhotic-patients-a-prospective-cohort-study
#9
Chih-Wei Liu, Chia-Chang Huang, Hung-Cheng Tsai, Yen-Bo Su, Shiang-Fen Huang, Kuei-Chuan Lee, Yun-Cheng Hsieh, Tzu-Hao Li, Chang-Youh Tsai, Lee-Won Chong, Shuo-Ming Ou, Ying-Ying Yang, Wen-Chien Fan, Ming-Chih Hou, Han-Chieh Lin, Shou-Dong Lee
AIMS: Increases in the systemic vasodilator adrenomedullin and the renal vasoconstrictors thromboxane A2 (TXA2 ) in cirrhotic patients are pathogenic factors for the development of functional acute-kidney-injury, including pre-renal azotemia (PRA) and hepatorenal syndrome (HRS), which is associated with high mortality. This study aims to find biomarkers which can diagnose HRS in early stage for treating it as soon as possible. METHODS: Acute decompensated cirrhotic patients who had been admitted to hospital were enrolled in this prospective cohort study...
May 20, 2017: Hepatology Research: the Official Journal of the Japan Society of Hepatology
https://www.readbyqxmd.com/read/28544495/posterior-lumbar-interbody-fusion-with-interspinous-fastener-provides-comparable-clinical-outcome-and-fusion-rate-to-pedicle-screws
#10
Wei-Min Huang, Xing-Ming Yu, Xiao-Duo Xu, Ruo-Xian Song, Li-Li Yu, Xiu-Chun Yu
OBJECTIVE: To investigate the clinical feasibility and validity of interspinous fastener (ISF) for lumbar degenerative diseases. METHODS: From October 2013 to March 2014, a total of 46 patients suffering from lumbar degenerative diseases underwent posterior lumbar interbody fusion (PLIF) randomly augmented by ISF or pedicle screws. The clinical outcome was primarily measured by Oswestry Disability Index (ODI) score. The minimal clinical important difference (MCID) was defined as an eight-point decrease in ODI...
May 24, 2017: Orthopaedic Surgery
https://www.readbyqxmd.com/read/28544311/impact-of-body-mass-index-on-robotic-radical-cystectomy-with-intra-corporeal-urinary-diversion
#11
Nariman Ahmadi, Thomas G Clifford, Gus Miranda, Jie Cai, Monish Aron, Mihir M Desai, Inderbir S Gill
OBJECTIVES: To determine the impact of body mass index (BMI) on peri-operative and oncological outcomes following robotic radical cystectomy (RRC) with intra-corporeal urinary diversion (ICUD). SUBJECTS AND METHODS: A total of 216 patients undergoing RRC, extended lymphadenectomy and ICUD (07/2010-12/2015) were categorized into four BMI groups according to the 2004 World Health Organization (WHO) obesity classification: <25 kg/m(2) (normal), 25-29.9 kg/m(2) (pre-obese), 30-34...
May 22, 2017: BJU International
https://www.readbyqxmd.com/read/28544302/predictors-of-delay-to-cystoscopy-and-adequacy-of-investigations-in-patients-with-haematuria
#12
Brian Ngo, Nathan Papa, Marlon Perera, Damien Bolton, Shomik Sengupta
OBJECTIVE: To identify factors that impact on the timeliness and adequacy of haematuria evaluation. PATIENTS AND METHODS: We undertook a retrospective cohort study identifying patients who underwent cystoscopy for investigation of haematuria at our institution between 1 January 2015 and 31 December 2015. Data on patient demographics, smoking status, anticoagulation, type of haematuria and referring clinician were collected. Exclusion criteria included patient age <18 years, known history of bladder/urinary tract/renal cancer, cystoscopy for indications other than haematuria and unknown date of urology consultation...
May 2017: BJU International
https://www.readbyqxmd.com/read/28544120/prognostic-significance-of-aortic-valve-gradient-in-patients-with-severe-aortic-stenosis-undergoing-transcatheter-aortic-valve-replacement
#13
Guy Witberg, Arik Finkelstein, Issi Barbash, Abid Assali, Yaron Shapira, Amit Segev, Amir Halkin, Paul Fefer, Jeremy Ben-Shoshan, Maayan Konigstein, Alexander Sagie, Victor Guetta, Ran Kornowski, Alon Barsheshet
OBJECTIVE: To evaluate the effect of baseline aortic valve gradient (AVG) both as a continuous and a categorical variable on mortality in patients undergoing transcatheter aortic valve replacement (TAVR), focusing on the high-gradient severe aortic stenosis (AS) patients. BACKGROUND: Identifying new predictors of mortality in the TAVR population can help refine risk stratification and improve the patient selection process for this procedure. So far, AVG has mainly been studied as a categorical variable and there is a paucity of data on its prognostic value as a continuous variable, especially in patients with high AVG AS, who constitute the majority of patients referred for TAVR...
May 22, 2017: Catheterization and Cardiovascular Interventions
https://www.readbyqxmd.com/read/28543931/severe-asthma-in-children
#14
REVIEW
Andrew Bush, Louise Fleming, Sejal Saglani
Most children with asthma have their disease easily controlled if low-dose inhaled corticosteroids (ICSs) are regularly and correctly administered. If a child presents with asthma which is apparently resistant to therapy with high-dose ICS and other controllers, then they have problematic severe asthma. However, in light of the UK National Review of Asthma Deaths, definitions of severe asthma based solely on the levels of prescribed treatment are too narrow. A detailed assessment of all such children should be performed...
May 25, 2017: Respirology: Official Journal of the Asian Pacific Society of Respirology
https://www.readbyqxmd.com/read/28543844/death-and-liver-transplantation-within-two-years-of-onset-of-drug-induced-liver-injury
#15
Paul H Hayashi, Don Rockey, Robert J Fontana, Hans L Tillmann, Neil Kaplowitz, Huiman Barnhart, Jiezhan Gu, Naga P Chalasani, K Rajender Reddy, Averell H Sherker, Jay H Hoofnagle
Drug-induced liver injury (DILI) is an important cause of death and indication for liver transplantation (fatality). The role of DILI in these fatalities ispoorly characterized particularly when fatalities occur > 26 weeks after DILI onset. We analyzed patients in the U.S. Drug-Induced Liver Injury Network prospective study having a fatal outcome within 2 years of onset. Each case was reviewed by 8 Network investigators and categorized as DILI having a primary, contributory or no role in the fatality...
May 23, 2017: Hepatology: Official Journal of the American Association for the Study of Liver Diseases
https://www.readbyqxmd.com/read/28543084/population-pharmacokinetics-and-exposure-response-assessment-of-cc-292-a-potent-btk-inhibitor-in-patients-with-chronic-lymphocytic-leukemia
#16
Yan Li, Francisco Ramírez-Valle, Yongjun Xue, Judith I Ventura, Olivier Gouedard, Jay Mei, Kenichi Takeshita, Maria Palmisano, Simon Zhou
CC-292, a potent Bruton tyrosine kinase inhibitor, is under development for the treatment of B-cell malignancies. An analysis was performed to develop a population pharmacokinetic model of CC-292 and assess the influence of demographics and disease-related covariates on CC-292 exposure and to assess the exposure-response (overall response rate) relationship in patients with chronic lymphocytic leukemia. Population pharmacokinetic analysis was based on a 2-compartment base model conducted in NONMEM. Categorical exposure-response analysis was performed using logistic regression in SAS...
May 19, 2017: Journal of Clinical Pharmacology
https://www.readbyqxmd.com/read/28542911/changes-in-patient-quality-of-life-during-oral-immunotherapy-for-food-allergy
#17
Na'ama Epstein Rigbi, Michael R Goldberg, Michael B Levy, Liat Nachshon, Keren Golobov, Arnon Elizur
BACKGROUND: Quality of life is (QOL) impaired in patients with food allergy and improves following oral immunotherapy (OIT). However, the treatment itself is prolonged and demanding. We examined changes in patient QOL during OIT for food allergy. METHODS: The FAQLQ-PF was administered to children aged 4-12 years undergoing OIT for milk, peanut or egg allergy, at the beginning and after 4 months of treatment. Patients were categorized as improved, unchanged, or diminished FAQLQ-PF (>0...
May 22, 2017: Allergy
https://www.readbyqxmd.com/read/28542847/-american%C3%A2-%C3%A2-english-speaker-before-american%C3%A2-%C3%A2-white-the-development-of-children-s-reasoning-about-nationality
#18
Jasmine M DeJesus, Hyesung G Hwang, Jocelyn B Dautel, Katherine D Kinzler
Adults implicitly judge people from certain social backgrounds as more "American" than others. This study tests the development of children's reasoning about nationality and social categories. Children across cultures (White and Korean American children in the United States, Korean children in South Korea) judged the nationality of individuals varying in race and language. Across cultures, 5- to 6-year-old children (N = 100) categorized English speakers as "American" and Korean speakers as "Korean" regardless of race, suggesting that young children prioritize language over race when thinking about nationality...
May 24, 2017: Child Development
https://www.readbyqxmd.com/read/28542693/macular-sensitivity-measured-with-microperimetry-in-stargardt-disease-in-the-progression-of-atrophy-secondary-to-stargardt-disease-progstar-study-report-no-7
#19
Etienne M Schönbach, Yulia Wolfson, Rupert W Strauss, Mohamed A Ibrahim, Xiangrong Kong, Beatriz Muñoz, David G Birch, Artur V Cideciyan, Gesa-Astrid Hahn, Muneeswar Nittala, Janet S Sunness, SriniVas R Sadda, Sheila K West, Hendrik P N Scholl
Importance: New outcome measures for treatment trials for Stargardt disease type 1 (STGD1) and other macular diseases are needed. Microperimetry allows mapping of light sensitivity of the macula and provides topographic information on visual function beyond visual acuity. Objective: To measure and analyze retinal light sensitivity of the macula in STGD1 using fundus-controlled perimetry (microperimetry). Design, Setting, and Participants: This was a multicenter prospective cohort study...
May 25, 2017: JAMA Ophthalmology
https://www.readbyqxmd.com/read/28542658/-cardiovascular-disease-in-pediatric-patients-under-chronic-peritoneal-dialysis
#20
Paula Lehmann F, Francisco Cano Sc
Peritoneal dialysis (PD) is the most common renal replacement therapy used in pediatric patients with end stage renal disease. This population has a mortality rate 1,000 times greater compare to pediatric population, mainly due to cardiovascular causes. OBJECTIVE: To characterize pediatric patients on chronic PD in relation to dialysis and cardiovascular outcome. PATIENTS AND METHODS: Cross sectional study. Patients in stable PD according to DOQI criteria were selected...
April 2017: Revista Chilena de Pediatría
keyword
keyword
49754
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"