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https://www.readbyqxmd.com/read/29778925/deep-learning-strategy-for-accurate-carotid-intima-media-thickness-measurement-an-ultrasound-study-on-japanese-diabetic-cohort
#1
Mainak Biswas, Venkatanareshbabu Kuppili, Tadashi Araki, Damodar Reddy Edla, Elisa Cuadrado Godia, Luca Saba, Harman S Suri, Tomaž Omerzu, John R Laird, Narendra N Khanna, Andrew Nicolaides, Jasjit S Suri
MOTIVATION: The carotid intima-media thickness (cIMT) is an important biomarker for cardiovascular diseases and stroke monitoring. This study presents an intelligence-based, novel, robust, and clinically-strong strategy that uses a combination of deep-learning (DL) and machine-learning (ML) paradigms. METHODOLOGY: A two-stage DL-based system (a class of AtheroEdge™ systems) was proposed for cIMT measurements. Stage I consisted of a convolution layer-based encoder for feature extraction and a fully convolutional network-based decoder for image segmentation...
May 12, 2018: Computers in Biology and Medicine
https://www.readbyqxmd.com/read/29778691/alterations-in-apparent-diffusion-coefficient-values-of-the-kidney-during-the-cardiac-cycle-evaluation-with-ecg-triggered-diffusion-weighted-mr-imaging
#2
Katsuyoshi Ito, Minoru Hayashida, Akihiko Kanki, Akira Yamamoto, Tsutomu Tamada, Koji Yoshida, Masahiro Tanabe
PURPOSE: To evaluate dynamic changes in apparent diffusion coefficient (ADC) values of the kidney at different time points during the cardiac cycle using electrocardiographic (ECG)-triggered diffusion-weighted MR imaging in normal subjects, and to elucidate the differences in ADC values between the right and left kidneys during a cardiac cycle. MATERIALS AND METHODS: The study was approved by our institutional review board and informed consent was obtained from subjects...
May 17, 2018: Magnetic Resonance Imaging
https://www.readbyqxmd.com/read/29778018/phytochemistry-and-pharmacology-of-anti-depressant-medicinal-plants-a-review
#3
REVIEW
Jeanette Martins, Brijesh S
Stress renders an individual to experience mental pressure and exhaustion which brings about feelings of anxiety, depression, anger and/or other negative emotions. Depression affects a person's state of mind, behaviour, health and is often associated with suicide. The use of anti-depressant drugs as therapeutic agents is associated with symptoms such as, delayed onset of action, side-effects, drug-drug and dietary interactions, sexual dysfunction, cardiac toxicity, etc. Thus, there is need to target these issues and improve current treatment options...
May 16, 2018: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
https://www.readbyqxmd.com/read/29777714/efficiency-of-neuromuscular-electrical-stimulation-and-transcutaneous-nerve-stimulation-on-hemiplegic-shoulder-pain-a-prospective-randomized-controlled-trial
#4
Meimei Zhou, Fang Li, Weibo Lu, Junfa Wu, Song Pei
OBJECTIVE: To compare the efficacy of neuromuscular electrical stimulation (NMES) and transcutaneous nerve stimulation (TENS) on hemiplegic shoulder pain (HSP). DESIGN: This is a prospective randomized controlled trial (RCT). SETTING: A total of 184 HSP patients, aged 18-80 years, were recruited in the Rehabilitation Hospital from February 2014 to July 2016. The Ethics approval was obtained from the Institutional Review Board of the Hospital...
May 16, 2018: Archives of Physical Medicine and Rehabilitation
https://www.readbyqxmd.com/read/29777418/earliest-radiological-progression-in-glioblastoma-by-multidisciplinary-consensus-review
#5
Roelant S Eijgelaar, Anna M E Bruynzeel, Frank J Lagerwaard, Domenique M J Müller, Freek R Teunissen, Frederik Barkhof, Marcel van Herk, Philip C De Witt Hamer, Marnix G Witte
BACKGROUND: Detection of glioblastoma progression is important for clinical decision-making on cessation or initiation of therapy, for enrollment in clinical trials, and for response measurement in time and location. The RANO-criteria are considered standard for the timing of progression. To evaluate local treatment, we aim to find the most accurate progression location. We determined the differences in progression free survival (PFS) and in tumor volumes at progression (Vprog) by three definitions of progression...
May 18, 2018: Journal of Neuro-oncology
https://www.readbyqxmd.com/read/29777334/patient-engagement-in-community-health-center-leadership-how-does-it-happen
#6
Anjana E Sharma, Beatrice Huang, Margae Knox, Rachel Willard-Grace, Michael B Potter
Patient engagement in primary care leadership is an important means to involve community voices at community health centers. Federally qualified health centers (FQHCs) are mandated to have patient representation within their governing boards, while practices seeking patient-centered medical home certification receive credit for implementing patient advisory councils (PACs). Our objective was to compare and contrast how community health centers engage patients in clinic management, decision-making and planning within governing boards versus PACs...
May 18, 2018: Journal of Community Health
https://www.readbyqxmd.com/read/29775663/free-breathing-ultrashort-echo-time-lung-magnetic-resonance-imaging-using-stack-of-spirals-acquisition-a-feasibility-study-in-oncology-patients
#7
Min Jae Cha, Hyun Jeong Park, Mun Young Paek, Alto Stemmer, Eun Sun Lee, Sung Bin Park, Yang Soo Kim
OBJECTIVES: To investigate the diagnostic accuracy of lung magnetic resonance imaging (MRI) with a free-breathing three-dimensional ultrashort echo time spoiled gradient echo sequence using a stack-of-spirals acquisition (spiral 3D UTE) for pulmonary nodule detection at 3 T in oncology patients. METHODS: The institutional review board approved this retrospective study. Between June and September of 2017, 32 oncology patients underwent both free-breathing spiral 3D UTE of the lungs and thin-section chest computed tomography (CT) for pulmonary metastasis workups...
May 15, 2018: Magnetic Resonance Imaging
https://www.readbyqxmd.com/read/29774382/iodine-material-density-images-in-dual-energy-ct-quantification-of-contrast-uptake-and-washout-in-hcc
#8
Daniela Pfeiffer, Anushri Parakh, Manuel Patino, Avinash Kambadakone, Ernst J Rummeny, Dushyant V Sahani
PURPOSE: To determine the diagnostic potential of Material Density (MD) iodine images in dual-energy CT (DECT) for visualization and quantification of arterial phase hyperenhancement and washout in hepatocellular carcinomas compared to magnetic resonance imaging (MRI). MATERIALS AND METHODS: The study complied with HIPAA guidelines and was approved by the ethics committee of the institutional review board. Thirty-one patients (23 men, 8 women; age range, 36-87 years) with known or suspected Hepatocellular Carcinoma (HCC) were included...
May 17, 2018: Abdominal Radiology
https://www.readbyqxmd.com/read/29774183/quantitative-parameters-of-intravoxel-incoherent-motion-diffusion-weighted-imaging-ivim-dwi-potential-application-in-predicting-pathological-grades-of-pancreatic-ductal-adenocarcinoma
#9
Wanling Ma, Guangwen Zhang, Jing Ren, Qi Pan, Didi Wen, Jinman Zhong, Zhuoli Zhang, Yi Huan
Background: The aim of this study was to compare intravoxel incoherent motion diffusion weighted imaging (IVIM-DWI) parameters such as standard apparent diffusion coefficient (ADCstandard ), pure diffusion coefficient (Dslow ), pseudodiffusion coefficient (Dfast ) and perfusion fraction (ƒ) for differentiating pancreatic ductal adenocarcinoma (PDAC) with different pathological grades. Methods: Institutional Review Board of our hospital approved this study protocol...
April 2018: Quantitative Imaging in Medicine and Surgery
https://www.readbyqxmd.com/read/29774180/survival-prediction-based-on-qualitative-mri-diffusion-signature-in-patients-with-recurrent-high-grade-glioma-treated-with-bevacizumab
#10
Pradeep Goyal, Mary Tenenbaum, Sonali Gupta, Puneet S Kochar, Alok A Bhatt, Manisha Mangla, Yogesh Kumar, Rajiv Mangla
Background: Bevacizumab was approved by the FDA for the treatment of recurrent or progressive glioblastoma (GBM). Imaging responses are typically assessed by gadolinium-enhanced MRI. We sought to determine the significance of qualitative diffusion signature (manifest as variable degree of dark signal) on ADC maps in recurrent gliomas after treatment with bevacizumab. Methods: We performed an institutional review board (IRB) approved retrospective study on patients who underwent MRI of the brain after 8 weeks of receiving bevacizumab for recurrent glioma...
April 2018: Quantitative Imaging in Medicine and Surgery
https://www.readbyqxmd.com/read/29773699/comparison-of-the-effect-of-immediate-versus-delayed-transfer-following-a-stimulated-ivf-cycle-on-the-ongoing-pregnancy-rate-of-frozen-thawed-embryo-transfer-cycles-a-study-protocol-for-a-randomised-controlled-trial
#11
He Li, Lu Li, Xiang Lu, Xiaoxi Sun, Ernest Hung Yu Ng
INTRODUCTION: Frozen-thawed embryo transfer (FET) has become an increasingly important part of in-vitro fertilisation (IVF) treatment. Currently, there is still no good scientific evidence to support when to perform FET following a stimulated IVF cycle. Since all published studies are retrospective and the findings are contradictory, a randomised controlled study is needed to provide Level 1 evidence to guide the clinical practice. METHODS/ANALYSIS: This is a randomised controlled trial...
May 17, 2018: BMJ Open
https://www.readbyqxmd.com/read/29773458/outcomes-of-conventional-phacoemulsification-versus-femtosecond-laser-assisted-cataract-surgery-in-eyes-with-fuchs-endothelial-corneal-dystrophy
#12
Dagny C Zhu, Parth Shah, William J Feuer, Wei Shi, Ellen H Koo
PURPOSE: To compare the outcomes in eyes with Fuchs endothelial corneal dystrophy after standard phacoemulsification with those of femtosecond laser-assisted cataract surgery. SETTING: Bascom Palmer Eye Institute, Miami, Florida, USA. DESIGN: Retrospective case series. METHODS: Charts from patients diagnosed with Fuchs endothelial corneal dystrophy who had phacoemulsification cataract surgery at Bascom Palmer Eye Institute between January 1, 2014, and January 1, 2017, were reviewed...
May 15, 2018: Journal of Cataract and Refractive Surgery
https://www.readbyqxmd.com/read/29772609/measuring-outcomes-of-digital-technology-assisted-nursing-postpartum-a-randomized-controlled-trial
#13
Deborah E Mccarter, Eugene Demidenko, Mark T Hegel
AIM: To determine if delivering electronic messages from nurses during the first six months postpartum is feasible, acceptable and effective in improving mood and decreasing parenting stress. BACKGROUND: Competing demands during the postpartum hospitalization make focused time for nurses to provide education and support difficult. Unmet needs following discharge may increase the incidence of postpartum depression. Untreated depression negatively affects families, especially for vulnerable women with limited access to health care...
May 17, 2018: Journal of Advanced Nursing
https://www.readbyqxmd.com/read/29770848/imaging-biomarkers-from-multiparametric-magnetic-resonance-imaging-are-associated-with-survival-outcomes-in-patients-with-brain-metastases-from-breast-cancer
#14
Bang-Bin Chen, Yen-Shen Lu, Chih-Wei Yu, Ching-Hung Lin, Tom Wei-Wu Chen, Shwu-Yuan Wei, Ann-Lii Cheng, Tiffany Ting-Fang Shih
OBJECTIVES: The aim of this study is to investigate the correlation of survival outcomes with imaging biomarkers from multiparametric magnetic resonance imaging (MRI) in patients with brain metastases from breast cancer (BMBC). METHODS: This study was approved by the institutional review board. Twenty-two patients with BMBC who underwent treatment involving bevacizumab on day 1, etoposide on days 2-4, and cisplatin on day 2 in 21-day cycles were prospectively enrolled for a phase II study...
May 16, 2018: European Radiology
https://www.readbyqxmd.com/read/29770484/inter-method-reproducibility-of-biexponential-r-2-mr-relaxometry-for-estimation-of-liver-iron-concentration
#15
Ali Pirasteh, Qing Yuan, Diego Hernando, Scott B Reeder, Ivan Pedrosa, Takeshi Yokoo
PURPOSE: To assess the reproducibility of biexponential R2 -relaxometry MRI for estimation of liver iron concentration (LIC) between proprietary and nonproprietary analysis methods. METHODS: This single-center retrospective study, approved by investigational review board and compliant with the Health Insurance Portability and Accountability Act, included 40 liver MRI exams in 38 subjects with suspected or known iron overload. From spin-echo images of the liver, acquired at 5 different echo times (TE = 6-18 ms), biexponential R2 maps were calculated using 1 proprietary (FerriScan, Resonance Health Ltd...
May 16, 2018: Magnetic Resonance in Medicine: Official Journal of the Society of Magnetic Resonance in Medicine
https://www.readbyqxmd.com/read/29768977/primary-care-physicians-perceptions-of-practice-improvement-as-a-professional-responsibility-a-cross-sectional-study
#16
Christopher R Stephenson, Christopher M Wittich, Joel E Pacyna, Matthew K Wynia, Omar Hasan, Jon C Tilburt
Continuous quality improvement is a component of professionalism. Maintenance of Certification (MOC) is a mechanism in the USA for physicians to keep current with medical knowledge and contribute to practice improvement. Little is known about primary care physicians' perceptions of the practice improvement (Part IV) components of MOC. We aimed to determine primary care physicians' perceptions of their professional responsibility to participate in Part IV MOC. This was a cross-sectional study of primary care physicians using the American Medical Association Masterfile...
December 2018: Medical Education Online
https://www.readbyqxmd.com/read/29768415/automated-and-real-time-segmentation-of-suspicious-breast-masses-using-convolutional-neural-network
#17
Viksit Kumar, Jeremy M Webb, Adriana Gregory, Max Denis, Duane D Meixner, Mahdi Bayat, Dana H Whaley, Mostafa Fatemi, Azra Alizad
In this work, a computer-aided tool for detection was developed to segment breast masses from clinical ultrasound (US) scans. The underlying Multi U-net algorithm is based on convolutional neural networks. Under the Mayo Clinic Institutional Review Board protocol, a prospective study of the automatic segmentation of suspicious breast masses was performed. The cohort consisted of 258 female patients who were clinically identified with suspicious breast masses and underwent clinical US scan and breast biopsy...
2018: PloS One
https://www.readbyqxmd.com/read/29768297/pediatric-esophageal-foreign-body-possible-role-for-digital-tomosynthesis
#18
Andrew Johansen, Gregory P Conners, Jacob Lee, Amie L Robinson, William L Chew, Sherwin S Chan
OBJECTIVES: Foreign body (FB) ingestion is a common reason for emergency department visits, affecting more than 80,000 children in the United States annually. Whereas most ingested FBs are coins or other radiopaque objects, some are radiolucent FBs such as food. Digital tomosynthesis (DTS) is a radiographic technique that produces cross-sectional images with in-plane resolution similar to that of traditional radiographs. Our pilot study evaluated the sensitivity and specificity of DTS to detect FB in comparison to esophagram and clinical impression...
May 15, 2018: Pediatric Emergency Care
https://www.readbyqxmd.com/read/29768053/quality-of-life-and-patients-expectations-in-soft-tissue-sarcoma
#19
Robin L Jones, Axel Le Cesne
Assessment of health-related quality of life (HRQoL) is essential for holistic care. Greater efforts are required to incorporate HRQoL measures into clinical trials and daily practice. Considerable HRQoL data are available for localized soft tissue sarcomas (STS), particularly in the orthopedic setting. In future, HRQoL is expected to become increasingly important in the evaluation of palliative therapy in advanced STS. A patient-centric approach is advocated for STS management. Greater awareness of STS by nonspecialist clinicians, and timely referral to specialized sarcoma reference centers, is crucial for patient welfare...
May 2018: Future Oncology
https://www.readbyqxmd.com/read/29767272/the-esska-afas-international-consensus-statement-on-peroneal-tendon-pathologies
#20
REVIEW
Pim A van Dijk, David Miller, James Calder, Christopher W DiGiovanni, John G Kennedy, Gino M Kerkhoffs, Akos Kynsburtg, Daniel Havercamp, Stephane Guillo, Xavier M Oliva, Chris J Pearce, Helder Pereira, Pietro Spennacchio, Joanna M Stephen, C Niek van Dijk
INTRODUCTION: Peroneal tendon injuries are a significant cause of lateral ankle symptoms in the active population. Accurate diagnosis and prompt treatment is important for minimizing the risk of long-term sequelae associated with chronic peroneal tendinopathy. Although several studies have been published on diagnostic strategies and treatment outcomes, there is no consensus on the optimal management of peroneal tendon pathologies. PURPOSE: The purpose of this ESSKA-AFAS consensus statement was to conduct an international and multidisciplinary agreed guideline on management of patients with peroneal tendon pathologies...
May 16, 2018: Knee Surgery, Sports Traumatology, Arthroscopy: Official Journal of the ESSKA
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