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https://www.readbyqxmd.com/read/28807739/community-based-participatory-research-to-design-a-faith-enhanced-diabetes-prevention-program-the-better-me-within-randomized-trial
#1
Heather Kitzman, Leilani Dodgen, Abdullah Mamun, J Lee Slater, George King, Donna Slater, Alene King, Surendra Mandapati, Mark DeHaven
Reducing obesity positively impacts diabetes and cardiovascular risk; however, evidence-based lifestyle programs, such as the diabetes prevention program (DPP), show reduced effectiveness in African American (AA) women. In addition to an attenuated response to lifestyle programs, AA women also demonstrate high rates of obesity, diabetes, and cardiovascular disease. To address these disparities, enhancements to evidence-based lifestyle programs for AA women need to be developed and evaluated with culturally relevant and rigorous study designs...
August 11, 2017: Contemporary Clinical Trials
https://www.readbyqxmd.com/read/28805484/disparate-phospho-smad2-levels-in-advanced-type-2-diabetes-patients-with-diabetic-nephropathy-and-early-experimental-db-db-mouse-model
#2
Lise Høj Thomsen, Morten Fog-Tonnesen, Lisbeth Nielsen Fink, Jenny Norlin, Amaya García de Vinuesa, Troels Krarup Hansen, Emile de Heer, Peter Ten Dijke, Alexander Rosendahl
Uncontrolled activation of transforming growth factor beta (TGF-β) family members is hypothesized to participate in type 2 diabetes (T2D) dependent diabetic nephropathy (DN). We evaluated and compared downstream activation of the Smad2-signaling pathway in kidney samples from T2D patients to kidneys from the T2D model of leptin receptor deficient db/db mouse. Furthermore, expression of TGF-β family members was evaluated to elucidate molecular mechanisms in the mouse model. Kidney samples from patients with advanced stages of DN showed elevated pSmad2 staining whereas db/db mouse kidneys surprisingly showed a decrease in pSmad2 in the tubular compartment...
November 2017: Renal Failure
https://www.readbyqxmd.com/read/28803840/development-and-validation-of-risk-equations-for-complications-of-type-2-diabetes-recode-using-individual-participant-data-from-randomised-trials
#3
Sanjay Basu, Jeremy B Sussman, Seth A Berkowitz, Rodney A Hayward, John S Yudkin
BACKGROUND: In view of substantial mis-estimation of risks of diabetes complications using existing equations, we sought to develop updated Risk Equations for Complications Of type 2 Diabetes (RECODe). METHODS: To develop and validate these risk equations, we used data from the Action to Control Cardiovascular Risk in Diabetes study (ACCORD, n=9635; 2001-09) and validated the equations for microvascular events using data from the Diabetes Prevention Program Outcomes Study (DPPOS, n=1018; 1996-2001), and for cardiovascular events using data from the Action for Health in Diabetes (Look AHEAD, n=4760; 2001-12)...
August 10, 2017: Lancet Diabetes & Endocrinology
https://www.readbyqxmd.com/read/28803784/race-ethnic-disparities-in-cardiometabolic-risk-profiles-among-stroke-survivors-with-undiagnosed-diabetes-and-prediabetes-in-the-united-states
#4
Okkyung Kim, Bruce Ovbiagele, Natalie Valle, Daniela Markovic, Amytis Towfighi
BACKGROUND AND PURPOSE: Up to 25% of the U.S. population has undiagnosed diabetes. Diabetes and stroke both disproportionately afflict race/ethnic minorities. We assessed race/ethnic differences in the prevalence of undiagnosed diabetes, prediabetes, and cardiometabolic risk profiles among stroke survivors in the United States. METHODS: The prevalence of diabetes and prediabetes among adults (≥20 years) with a self-reported history of stroke was assessed using the National Health and Nutrition Examination Surveys (NHANES) from 1999 to 2010...
August 10, 2017: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
https://www.readbyqxmd.com/read/28801394/the-role-of-nurse-specialists-in-the-delivery-of-integrated-diabetes-care-a-cross-sectional-survey-of-diabetes-nurse-specialist-services
#5
Fiona Riordan, Sheena M McHugh, Katie Murphy, Julie Barrett, Patricia M Kearney
OBJECTIVES: International evidence suggests the diabetes nurse specialist (DNS) has a key role in supporting integrated management of diabetes. We examine whether hospital and community DNS currently support the integration of care, examine regional variation in aspects of the service relevant to the delivery of integrated care and identify barriers to service delivery and areas for improvement. DESIGN: A cross-sectional survey of hospital and community-based DNS in Ireland...
August 11, 2017: BMJ Open
https://www.readbyqxmd.com/read/28799212/excess-psychosocial-burden-in-women-with-diabetes-and-premature-acute-coronary-syndrome
#6
T M Peters, R Pelletier, H Behlouli, A M Rossi, L Pilote
AIM: Diabetes is a stronger risk factor for acute coronary syndrome for women than men. We investigate whether behavioural and psychosocial factors contribute to the disparity in acute coronary syndrome risk and outcomes among women with diabetes relative to women without diabetes and men. METHODS: Among 939 participants in the GENESIS-PRAXY cohort study of premature acute coronary syndrome (age ≤ 55 years), we compared the prevalence of traditional and non-traditional factors by sex and Type 2 diabetes status...
August 11, 2017: Diabetic Medicine: a Journal of the British Diabetic Association
https://www.readbyqxmd.com/read/28793887/examining-the-relationship-between-the-food-environment-and-adult-diabetes-prevalence-by-county-economic-and-racial-composition-an-ecological-study
#7
Lindsey Haynes-Maslow, Lucia A Leone
BACKGROUND: Inequitable access to healthy food may contribute to health disparities. This study examines the relationship between the prevalence of adult diabetes and food access in the U.S. by county economic/racial composition. METHODS: An ecological study from 2012 was used to estimate the relationship between diabetes and retail food outlet access. County diabetes prevalence was measured based on individual responses to the Behavioral Risk Factor Surveillance Survey question, "Have you ever been told by a doctor that you have diabetes?" If the answer was "yes" individuals were classified as having diabetes...
August 9, 2017: BMC Public Health
https://www.readbyqxmd.com/read/28791583/using-geospatial-analysis-and-emergency-claims-data-to-improve-minority-health-surveillance
#8
David C Lee, Stella S Yi, Jessica K Athens, Andrew J Vinson, Stephen P Wall, Joseph E Ravenell
Traditional methods of health surveillance often under-represent racial and ethnic minorities. Our objective was to use geospatial analysis and emergency claims data to estimate local chronic disease prevalence separately for specific racial and ethnic groups. We also performed a regression analysis to identify associations between median household income and local disease prevalence among Black, Hispanic, Asian, and White adults in New York City. The study population included individuals who visited an emergency department at least once from 2009 to 2013...
August 8, 2017: Journal of Racial and Ethnic Health Disparities
https://www.readbyqxmd.com/read/28776947/racial-disparities-in-the-utilization-of-preventive-health-services-among-older-women-with-early-stage-endometrial-cancer-enrolled-in-medicare
#9
Jovana Y Martin, Melissa A Schiff, Noel S Weiss, Renata R Urban
To assess differences in the receipt of preventive health services by race/ethnicity among older women with endometrial cancer enrolled in Medicare, we conducted a retrospective population-based cohort study of women diagnosed with endometrial cancer from 2001 to 2011 in the Surveillance Epidemiology and End Results (SEER)-Medicare database. Women with stage I or II endometrial cancer of epithelial origin were included. The exposure was race/ethnicity (Non-Hispanic [NH] White, NH Black, Hispanic, and NH Asian/Pacific Islander [PI])...
August 4, 2017: Cancer Medicine
https://www.readbyqxmd.com/read/28774505/association-of-dysfunctional-eating-patterns-and-metabolic-risk-factors-for-cardiovascular-disease-among-latinos
#10
Andrea Lopez-Cepero, Christine F Frisard, Stephenie C Lemon, Milagros C Rosal
BACKGROUND: Latinos are at high risk for cardiovascular disease (CVD). Identifying behavioral factors associated with CVD risk in this population may provide novel targets for further research to reduce chronic disease disparities. Dysfunctional eating patterns (emotional eating [EE], uncontrolled eating [UE], and cognitive restraint of eating [CR]) may be associated with CVD risk but little is known about this relationship in Latinos. OBJECTIVE: The aim of this study was to examine associations between dysfunctional eating patterns and metabolic risk factors for CVD in Latinos...
August 1, 2017: Journal of the Academy of Nutrition and Dietetics
https://www.readbyqxmd.com/read/28771089/cardiovascular-risk-screening-for-individuals-with-serious-mental-illness
#11
Denise R Black, Mary L Held
Cardiovascular disease (CVD) is a significant health risk for individuals with serious mental illness (SMI). Screening for CVD risk factors is a key strategy to reduce this health disparity. This study examined medical, lifestyle, and access predictors for comprehensive screening. Data on 1036 adults were analyzed from the 2015 National Health Interview Survey. Multivariate multinomial logistic regression was used to examine factors associated with individuals with SMI receiving CVD risk screening in the past 12 months...
August 3, 2017: Social Work in Health Care
https://www.readbyqxmd.com/read/28767292/us-healthcare-experiences-of-hispanic-patients-with-diabetes-and-family-members-a-qualitative-analysis
#12
Karen A Amirehsani, Jie Hu, Debra C Wallace, Zulema A Silva, Sarah Dick, Lauren N West-Livingston, Christina R Hussami
Hispanics in the United States experience significant health disparities. Using focus groups conducted in Spanish, we explored the perspectives of 172 Hispanic adults regarding their healthcare experiences. Many participants were women (64.5%) and primarily from Mexico (80%). Four major qualitative themes emerged: (a) provide us with information, (b) want attentive and respectful relationships, (c) want better care, and (d) perceived discrimination. Suboptimal patient-provider interactions were described. Research is needed to explore interventions that address these issues...
July 2017: Journal of Community Health Nursing
https://www.readbyqxmd.com/read/28760098/mind-the-gap-developing-an-integrated-behavioral-health-home-to-address-health-disparities-in-serious-mental-illness
#13
Miriam C Tepper, Alexander M Cohen, Ana M Progovac, Andrea Ault-Brutus, H Stephen Leff, Brian Mullin, Carrie M Cunningham, Benjamin Lê Cook
OBJECTIVE: This study evaluated the impact of an integrated behavioral health home (BHH) pilot on adults with psychotic and bipolar disorders. METHODS: Quasi-experimental methods were used to compare outcomes before (September 2014-August 2015) and after the intervention (September 2015-August 2016) among ambulatory BHH patients and a control group. Electronic health records were compared between 424 BHH patients (N=369, psychotic disorder; N=55, bipolar disorder) and 1,521 individuals from the same urban, safety-net health system who were not enrolled in the BHH...
August 1, 2017: Psychiatric Services: a Journal of the American Psychiatric Association
https://www.readbyqxmd.com/read/28759408/variation-in-formula-supplementation-of-breastfed-newborn-infants-in-new-york-hospitals
#14
Trang Nguyen, Barbara A Dennison, Wei Fan, Changning Xu, Guthrie S Birkhead
OBJECTIVES: We examined the variation between 126 New York hospitals in formula supplementation among breastfed infants after adjusting for socioeconomic, maternal, and infant factors and stratifying by level of perinatal care. METHODS: We used 2014 birth certificate data for 160 911 breastfed infants to calculate hospital-specific formula supplementation percentages by using multivariable hierarchical logistic regression models. RESULTS: Formula supplementation percentages varied widely among hospitals, from 2...
July 2017: Pediatrics
https://www.readbyqxmd.com/read/28756695/cardiometabolic-risks-lifestyle-health-behaviors-and-heart-disease-in-filipino-americans
#15
Maria Lg Bayog, Catherine M Waters
BACKGROUND: Cardiovascular disease is the leading cause of death among all racial and ethnic populations in the USA. Cardiovascular risks and cardioprotective factors have been disparately estimated among Asian American subpopulations. AIMS: The study's purpose was to describe the cardiometabolic risks and lifestyle health behaviors associated with cardiovascular disease, considering age and gender, in Filipinos, the second largest Asian American population. METHODS: Secondary analysis was conducted of behavioral (smoking, walking, body mass index and soda, fast food and fruit/vegetable consumption), cardiometabolic (hypertension and diabetes) and heart disease variables in the 2011-2012 California Health Interview Survey...
August 2017: European Journal of Cardiovascular Nursing
https://www.readbyqxmd.com/read/28750219/continuous-glucose-monitoring-detected-hypoglycaemia-in-the-treating-to-target-in-type-2-diabetes-trial-4-t
#16
J C Levy, M J Davies, R R Holman
AIMS: Hypoglycaemia is a significant risk in insulin treated type 2 diabetes and has been associated with future risk of cardiovascular events. We compared the frequency of low-glucose events using continuous glucose monitoring (CGM) with that of self-reported hypoglycemic events at the end of the first and third years of the Treating to Target in Type 2 Diabetes Trial (4-T), which compared biphasic, prandial and basal insulin regimens added to sulfonylurea and metformin. METHODS: CGM using a Medtronic Gold system was performed in a subgroup of 4-T participants...
March 21, 2017: Diabetes Research and Clinical Practice
https://www.readbyqxmd.com/read/28749729/understanding-the-role-of-message-frames-on-african-american-willingness-to-participate-in-a-hypothetical-diabetes-prevention-study
#17
Aisha T Langford, Knoll Larkin, Ken Resnicow, Brian J Zikmund-Fisher, Angela Fagerlin
The objective of this research was to evaluate the impact of message framing (e.g., highlighting health disparities vs. progress toward reducing disparities) on willingness to enroll in a hypothetical research study. African-American (AA, n = 1513) and White (n = 362) adults completed an online survey about diabetes, health behaviors including physical activity, and attitudes about research. AA participants were randomized to view a general message (same message as provided to all White participants) or 1 of 4 alternate messages that framed the need for people to participate in research in terms of race and/or health disparities...
July 27, 2017: Journal of Health Communication
https://www.readbyqxmd.com/read/28747349/outcomes-associated-with-a-pediatric-clinical-diabetes-network-in-ontario-a-population-based-time-trend-analysis
#18
Meranda Nakhla, Elham Rahme, Marc Simard, Astrid Guttmann
BACKGROUND: The Network of Ontario Pediatric Diabetes Programs was implemented in 2001. The objective of this study was to determine whether implementation of the network was associated with a decrease in the risk of acute diabetes-related complications and a reduction in the socioeconomic and geographic disparities in these outcomes. METHODS: We conducted a population-based time trend analysis of children (< 18 yr) with diabetes using health administrative databases in Ontario from 1996 to 2011...
July 24, 2017: CMAJ Open
https://www.readbyqxmd.com/read/28738686/disparities-in-diabetes-and-hypertension-care-for-individuals-with-serious-mental-illness
#19
Junqing Liu, Jonathan Brown, Suzanne Morton, D E B Potter, Lisa Patton, Milesh Patel, Rita Lewis, Sarah Hudson Scholle
OBJECTIVES: People with serious mental illnesses (SMI), including schizophrenia, bipolar disorder, and major depression, experience early mortality, partly due to comorbid physical health conditions such as diabetes and hypertension. This study examined the quality of diabetes and hypertension care for Medicaid and Medicare enrollees with SMI. STUDY DESIGN: We conducted a retrospective analysis of medical records and claims data from 3 health plans: a Medicaid plan for disabled adults, a Medicaid plan for low-income adults, and a Special Needs Plan for individuals dually enrolled in Medicaid and Medicare...
May 2017: American Journal of Managed Care
https://www.readbyqxmd.com/read/28735459/diabetes-and-the-hospitalized-patient-a-cluster-analytic-framework-for-characterizing-the-role-of-sex-race-and-comorbidity-from-2006-to-2011
#20
Nisha Nataraj, Julie Simmons Ivy, Fay Cobb Payton, Joseph Norman
In the US, one in four adults has two or more chronic conditions; this population accounts for two thirds of healthcare spending. Comorbidity, the presence of multiple simultaneous health conditions in an individual, is increasing in prevalence and has been shown to impact patient outcomes negatively. Comorbidities associated with diabetes are correlated with increased incidence of preventable hospitalizations, longer lengths of stay (LOS), and higher costs. This study focuses on sex and race disparities in outcomes for hospitalized adult patients with and without diabetes...
July 22, 2017: Health Care Management Science
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