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https://www.readbyqxmd.com/read/29330031/mental-health-disorders-mediate-association-of-sexual-minority-identity-with-cardiovascular-disease
#1
Lezhou Wu, Randy L Sell, Alexis M Roth, Seth L Welles
BACKGROUND: Little is known about cardiovascular health disparities for lesbian, gay, or bisexual (LGB) persons and whether these disparities are mediated by mental health disorders due to sexual minority stress. We hypothesize LGB identity is associated with an increased risk of cardiovascular disease (CVD) and that major depressive disorder (MDD) and generalized anxiety disorders (GAD) may mediate this association. METHODS: The National Epidemiologic Survey on Alcohol and Related Conditions is a longitudinal, nationally-representative study of non-institutionalized U...
January 9, 2018: Preventive Medicine
https://www.readbyqxmd.com/read/29317176/race-disparities-in-cardiovascular-disease-risk-factors-within-socioeconomic-status-strata
#2
Caryn N Bell, Roland J Thorpe, Janice V Bowie, Thomas A LaVeist
PURPOSE: Racial differences in socioeconomic status (SES) explain some, but not all, of racial disparities in cardiovascular disease (CVD) risk. To address this, race disparities among higher SES individuals need to be assessed. The purpose of this study was to assess whether racial disparities in CVD risk factors differ by SES levels. METHODS: Data from the National Health and Nutritional Examination Survey 2007-2014 were used to calculate racial differences in hypertension, high cholesterol, diabetes, and obesity...
December 22, 2017: Annals of Epidemiology
https://www.readbyqxmd.com/read/29313223/impact-of-a-population-health-management-intervention-on-disparities-in-cardiovascular-disease-control
#3
Aisha James, Seth A Berkowitz, Jeffrey M Ashburner, Yuchiao Chang, Daniel M Horn, Sandra M O'Keefe, Steven J Atlas
BACKGROUND: Healthcare systems use population health management programs to improve the quality of cardiovascular disease care. Adding a dedicated population health coordinator (PHC) who identifies and reaches out to patients not meeting cardiovascular care goals to these programs may help reduce disparities in cardiovascular care. OBJECTIVE: To determine whether a program that used PHCs decreased racial/ethnic disparities in LDL cholesterol and blood pressure (BP) control...
January 8, 2018: Journal of General Internal Medicine
https://www.readbyqxmd.com/read/29259233/cardiovascular-disease-progression-in-female-zucker-diabetic-fatty-rats-occurs-via-unique-mechanisms-compared-to-males
#4
Kelly Lum-Naihe, Ryan Toedebusch, Abuzar Mahmood, Jamal Bajwa, Terry Carmack, Senthil A Kumar, Sivakumar Ardhanari, Vincent G DeMarco, Craig A Emter, Lakshmi Pulakat
Population studies have shown that compared to diabetic men, diabetic women are at a higher risk of cardiovascular disease. However, the mechanisms underlying this gender disparity are unclear. Our studies in young murine models of type 2 diabetes mellitus (T2DM) and cardiovascular disease show that diabetic male rats develop increased cardiac fibrosis and suppression of intracardiac anti-fibrotic cytokines, while premenopausal diabetic female rats do not. This protection from cardiac fibrosis in female rats can be an estrogen-related effect...
December 19, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29241969/relation-of-ectopic-fat-with-atherosclerotic-cardiovascular-disease-risk-score-in-south-asians-living-in-the-united-states-from-the-mediators-of-atherosclerosis-in-south-asians-living-in-america-masala-study
#5
Morgana Mongraw-Chaffin, Unjali P Gujral, Alka M Kanaya, Namratha R Kandula, John Jeffrey Carr, Cheryl A M Anderson
Few studies have investigated the association between ectopic fat from different depots and cardiovascular risk scores and their components in the same population, and none have investigated these relations in South Asians. In a cross-sectional analysis of 796 participants in the Mediators of Atherosclerosis in South Asians Living in America (MASALA) study who had measurements of visceral, subcutaneous, pericardial, hepatic, and intermuscular fat from abdominal and cardiac computed tomography scans, we used linear regression to determine the associations of 1 standard deviation difference in each ectopic fat depot with pooled cohort risk score and its components...
October 31, 2017: American Journal of Cardiology
https://www.readbyqxmd.com/read/29240836/is-quality-of-life-different-between-diabetic-and-non-diabetic-people-the-importance-of-cardiovascular-risks
#6
L M Peña-Longobardo, B Rodríguez-Sánchez, M Mata-Cases, L Rodríguez-Mañas, M Capel, J Oliva-Moreno
BACKGROUND: To analyse and compare the impact of cardiovascular risk factors and disease on health-related quality of life (HRQoL) in people with and without diabetes living in the community. METHODS: We used data of 1,905 people with diabetes and 19,031 people without diabetes from the last Spanish National Health Survey (years 2011-2012). The HRQoL instrument used was the EuroQol 5D-5L, based on time trade-off scores. Matching methods were used to assess any differences in the HRQoL in people with and without diabetes with the same characteristics (age, gender, education level, and healthy lifestyle), according to cardiovascular risk factors and diseases...
2017: PloS One
https://www.readbyqxmd.com/read/29239999/care-management-to-reduce-disparities-and-control-hypertension-in-primary-care-a-cost-effectiveness-analysis
#7
Jonathan C Hong, William V Padula, Ilene L Hollin, Tanvir Hussain, Katherine B Dietz, Jennifer P Halbert, Jill A Marsteller, Lisa A Cooper
BACKGROUND: Project ReD CHiP (reducing disparities and controlling hypertension in primary care) care management was a clinic-based intervention that aimed to improve blood pressure control through improved care coordination and provide self-management support to patients from racially and socioeconomically. OBJECTIVE: To evaluate the cost-effectiveness of ReD CHiP care management versus standard care to treat hypertension in diverse communities. RESEARCH DESIGN: Microsimulation model from a health care sector perspective over 15 years...
December 12, 2017: Medical Care
https://www.readbyqxmd.com/read/29234990/african-americans-african-immigrants-and-afro-caribbeans-differ-in-social-determinants-of-hypertension-and-diabetes-evidence-from-the-national-health-interview-survey
#8
Yvonne Commodore-Mensah, Nadine Matthie, Jessica Wells, Sandra B Dunbar, Cheryl Dennison Himmelfarb, Lisa A Cooper, Rasheeta D Chandler
In the United States (U.S.), Blacks have higher morbidity and mortality from cardiovascular disease (CVD) than other racial groups. The Black racial group includes African Americans (AAs), African immigrants (AIs), and Afro-Caribbeans (ACs); however, little research examines how social determinants differentially influence CVD risk factors in each ethnic subgroup. We analyzed the 2010-2014 National Health Interview Survey, a cross-sectional, nationally representative survey of non-institutionalized civilians...
December 12, 2017: Journal of Racial and Ethnic Health Disparities
https://www.readbyqxmd.com/read/29208253/socioeconomic-psychosocial-and-behavioral-characteristics-of-patients-hospitalized-with-cardiovascular-disease
#9
Matthew E Dupre, Alicia Nelson, Scott M Lynch, Bradi B Granger, Hanzhang Xu, Erik Churchill, Janese M Willis, Lesley H Curtis, Eric D Peterson
BACKGROUND: Recent studies have drawn attention to nonclinical factors to better understand disparities in the development, treatment and prognosis of patients with cardiovascular disease. However, there has been limited research describing the nonclinical characteristics of patients hospitalized for cardiovascular care. METHODS: Data for this study come from 520 patients admitted to the Duke Heart Center from January 1, 2015 through January 10, 2017. Electronic medical records and a standardized survey administered before discharge were used to ascertain detailed information on patients' demographic (age, sex, race, marital status and living arrangement), socioeconomic (education, employment and health insurance), psychosocial (health literacy, health self-efficacy, social support, stress and depressive symptoms) and behavioral (smoking, drinking and medication adherence) attributes...
December 2017: American Journal of the Medical Sciences
https://www.readbyqxmd.com/read/29202104/a-health-profile-of-senior-aged-women-veterans-a-latent-class-analysis-of-condition-clusters
#10
Margaret E Gonsoulin, Ramon A Durazo-Arvizu, Karen M Goldstein, Guichan Cao, Qiuying Zhang, Dharani Ramanathan, Denise M Hynes
Background and Objectives: This study characterizes the multiple morbidities experienced by senior-aged women Veterans so that the Veterans Health Administration (VHA) and other healthcare systems may be better prepared to meet the healthcare needs of this growing cohort. Research Design and Methods: Using the VHA's Corporate Data Warehouse (CDW), we conducted a retrospective observational study of the 38,597 female veteran patients who were at least sixty-five years old and received care in the VHA during 2013 and 2014...
September 1, 2017: Innovation in Aging
https://www.readbyqxmd.com/read/29187391/implicit-gender-bias-and-the-use-of-cardiovascular-tests-among-cardiologists
#11
Stacie L Daugherty, Irene V Blair, Edward P Havranek, Anna Furniss, L Miriam Dickinson, Elhum Karimkhani, Deborah S Main, Frederick A Masoudi
BACKGROUND: Physicians' gender bias may contribute to gender disparities in cardiovascular testing. We used the Implicit Association Test to examine the association of implicit gender biases with decisions to use cardiovascular tests. METHODS AND RESULTS: In 2014, cardiologists completed Implicit Association Tests and a clinical vignette with patient gender randomly assigned. The Implicit Association Tests measured implicit gender bias for the characteristics of strength and risk taking...
November 29, 2017: Journal of the American Heart Association
https://www.readbyqxmd.com/read/29178869/the-potential-impact-of-food-taxes-and-subsidies-on-cardiovascular-disease-and-diabetes-burden-and-disparities-in-the-united-states
#12
José L Peñalvo, Frederick Cudhea, Renata Micha, Colin D Rehm, Ashkan Afshin, Laurie Whitsel, Parke Wilde, Tom Gaziano, Jonathan Pearson-Stuttard, Martin O'Flaherty, Simon Capewell, Dariush Mozaffarian
BACKGROUND: Fiscal interventions are promising strategies to improve diets, reduce cardiovascular disease and diabetes (cardiometabolic diseases; CMD), and address health disparities. The aim of this study is to estimate the impact of specific dietary taxes and subsidies on CMD deaths and disparities in the US. METHODS: Using nationally representative data, we used a comparative risk assessment to model the potential effects on total CMD deaths and disparities of price subsidies (10%, 30%) on fruits, vegetables, whole grains, and nuts/seeds and taxes (10%, 30%) on processed meat, unprocessed red meats, and sugar-sweetened beverages...
November 27, 2017: BMC Medicine
https://www.readbyqxmd.com/read/29173932/influence-of-intimate-partner-violence-ipv-exposure-on-cardiovascular-and-salivary-biosensors-is-there-a-relationship
#13
Leslie R Halpern, Malcolm L Shealer, Rian Cho, Elizabeth B McMichael, Joseph Rogers, Daphne Ferguson-Young, Charles P Mouton, Mohammad Tabatabai, Janet Southerland, Pandu Gangula
BACKGROUND/PURPOSE: Intimate partner violence (IPV) is a global public health epidemic that initiates/exacerbates health consequences affecting a victim's lifespan. IPV can significantly predispose women to a lifetime risk of developing cardiovascular disease (CVD) due to the effects of stress and inflammation. This study investigates the correlation among IPV exposure, in-vivo CVD events, and inflammatory biomarkers as predictor indices(s) for CVD in female dental patients. METHODS: Of 37 women enrolled in this study, 19 were African-American (AA) and 18 non-African-American (non-AA) and their ages ranged from 19 to 63 years...
January 2017: Journal of the National Medical Association
https://www.readbyqxmd.com/read/29167879/racial-differences-in-plasma-levels-of-n-terminal-pro-b-type-natriuretic-peptide-and-outcomes-the-reasons-for-geographic-and-racial-differences-in-stroke-regards-study
#14
Navkaranbir S Bajaj, Orlando M Gutiérrez, Garima Arora, Suzanne E Judd, Nirav Patel, Aleena Bennett, Sumanth D Prabhu, George Howard, Virginia J Howard, Mary Cushman, Pankaj Arora
Importance: Recent studies have suggested that the natriuretic peptide system may be endogenously suppressed in black individuals who are free of prevalent cardiovascular disease. Whether natriuretic peptide levels contribute to racial disparities in clinical outcomes is unknown. Objective: To examine racial differences in N-terminal pro-B-type natriuretic peptide (NTproBNP) levels and their association with all-cause mortality and cause-specific mortality in the Reasons for Geographic and Racial Differences in Stroke (REGARDS) study...
November 22, 2017: JAMA Cardiology
https://www.readbyqxmd.com/read/29166798/grk2-as-a-therapeutic-target-for-heart-failure
#15
Alessandro Cannavo, Klara Komici, Leonardo Bencivenga, Maria Loreta D'amico, Giuseppina Gambino, Daniela Liccardo, Nicola Ferrara, Giuseppe Rengo
G protein-coupled receptor (GPCR) kinase-2 (GRK2) is a regulator of GPCRs, in particular β-adrenergic receptors (ARs), and as demonstrated by decades of investigation, it has a pivotal role in the development and progression of cardiovascular disease, like heart failure (HF). Indeed elevated levels and activity of this kinase are able to promote the dysfunction of both cardiac and adrenal α- and β-ARs and to dysregulate other protective signaling pathway, such as sphingosine 1-phospate and insulin. Moreover, recent discoveries suggest that GRK2 can signal independently from GPCRs, in a 'non-canonical' manner, via interaction with non-GPCR molecule or via its mitochondrial localization...
January 2018: Expert Opinion on Therapeutic Targets
https://www.readbyqxmd.com/read/29150535/disparities-in-management-of-cardiovascular-disease-in-rural-south-africa-data-from-the-haalsi-study-health-and-aging-in-africa-longitudinal-studies-of-international-network-for-the-demographic-evaluation-of-populations-and-their-health-communities
#16
Thiago Veiga Jardim, Sheridan Reiger, Shafika Abrahams-Gessel, Nigel J Crowther, Alisha Wade, F Xavier Gómez-Olivé, Joshua Salomon, Stephen Tollman, Thomas A Gaziano
BACKGROUND: Optimal secondary prevention is critical for the reduction of repeated cardiovascular events, and the control of cardiovascular risk factors in this context is essential. Data on secondary prevention of cardiovascular disease (CVD) in sub-Saharan Africa are needed to inform intervention strategies with a particular focus on local disparities. The aim of this study was to assess CVD management in a rural community in northeast South Africa. METHODS AND RESULTS: We recruited adults aged ≥40 years residing in the Agincourt subdistrict of Mpumalanga province...
November 2017: Circulation. Cardiovascular Quality and Outcomes
https://www.readbyqxmd.com/read/29148344/moderating-effects-of-patient-characteristics-on-the-impact-of-financial-incentives
#17
Meredith B Rosenthal, Andrea B Troxel, Kevin G Volpp, Walter F Stewart, Thomas D Sequist, James B Jones, AnneMarie G Hirsch, Karen Hoffer, Jingsan Zhu, Wenli Wang, Amanda Hodlofski, Darra Finnerty, Jack J Huang, David A Asch
While financial incentives to providers or patients are increasingly common as a quality improvement strategy, their impact on patient subgroups and health care disparities is unclear. To examine these patterns, we analyzed data from a randomized clinical trial of financial incentives to lower low-density lipoprotein (LDL) cholesterol levels in patients at risk for cardiovascular disease. Patients with higher baseline LDL experienced greater cholesterol reductions in the shared incentive arm (0.23 mg/dL per unit change in baseline LDL, 95% CI [-0...
May 1, 2017: Medical Care Research and Review: MCRR
https://www.readbyqxmd.com/read/29145355/disparities-in-state-specific-adult-fruit-and-vegetable-consumption-united-states-2015
#18
Seung Hee Lee-Kwan, Latetia V Moore, Heidi M Blanck, Diane M Harris, Deb Galuska
The 2015-2020 Dietary Guidelines for Americans recommend that Americans consume more fruits and vegetables as part of an overall dietary pattern to reduce the risk for diet-related chronic diseases such as cardiovascular disease, type 2 diabetes, some cancers, and obesity (1). Adults should consume 1.5-2.0 cup equivalents of fruits and 2.0-3.0 cups of vegetables per day.* Overall, few adults in each state met intake recommendations according to 2013 Behavioral Risk Factor Surveillance System (BRFSS) data; however, sociodemographic characteristics known to be associated with fruit and vegetable consumption were not examined (2)...
November 17, 2017: MMWR. Morbidity and Mortality Weekly Report
https://www.readbyqxmd.com/read/29138366/lower-repeat-revascularization-rates-among-patients-with-prior-coronary-artery-bypass-graft-surgery-are-due-to-lack-of-adequate-target-vessels
#19
Anirudh Kumar, John F Wagener, Daniel Wojdyla, W Schuyler Jones, Manesh R Patel, Sunil V Rao
BACKGROUND: Studies comparing percutaneous coronary intervention (PCI) and coronary artery bypass graft (CABG) surgery in patients with multivessel coronary artery disease (CAD) have shown lower repeat revascularization rates in patients who undergo CABG. The reason remains unclear. METHODS: We identified patients with multivessel CAD who received CABG or PCI enrolled in the Duke Databank for Cardiovascular Disease (2003 to 2012). We compared the incidence of major adverse cardiovascular and cerebrovascular events (MACCE) between the two groups...
November 15, 2017: Journal of Invasive Cardiology
https://www.readbyqxmd.com/read/29138182/disparities-in-the-quality-of-cardiovascular-care-between-hiv-infected-versus-hiv-uninfected-adults-in-the-united-states-a-cross-sectional-study
#20
Joseph A Ladapo, Adam K Richards, Cassandra M DeWitt, Nina T Harawa, Steven Shoptaw, William E Cunningham, John N Mafi
BACKGROUND: Cardiovascular disease is emerging as a major cause of morbidity and mortality among patients with HIV. We compared use of national guideline-recommended cardiovascular care during office visits among HIV-infected versus HIV-uninfected adults. METHODS AND RESULTS: We analyzed data from a nationally representative sample of HIV-infected and HIV-uninfected patients aged 40 to 79 years in the National Ambulatory Medical Care Survey/National Hospital Ambulatory Medical Care Survey, 2006 to 2013...
November 14, 2017: Journal of the American Heart Association
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