keyword
https://read.qxmd.com/read/38530392/-not-available
#1
JOURNAL ARTICLE
Aron Schulze
No abstract text is available yet for this article.
March 26, 2024: NTM
https://read.qxmd.com/read/38528938/real-time-ultrasound-guided-thoracentesis-simulation-using-an-optical-see-through-head-mounted-display-a-proof-of-concept-study
#2
JOURNAL ARTICLE
Shotaro Okachi, Toshinori Matsui, Manami Sakurai, Takayasu Ito, Masahiro Morise, Kazuyoshi Imaizumi, Makoto Ishii, Michitaka Fujiwara
AIM: This study aimed to examine the feasibility and potential benefits of an optical see-through head-mounted display (OST-HMD) during real-time ultrasound-guided thoracentesis simulations. MATERIAL AND METHODS: Six physicians performed a thoracentesis simulation using an OST-HMD and a wireless image transmission system. The time required, puncture needle visibility, pleural fluid collection success rate, and head movement during the procedure using a smart glass equipped with an inertial measurement unit were all recorded and compared with and without the HMD...
February 2024: Journal of Ultrasonography
https://read.qxmd.com/read/38523298/evaluation-of-therapeutic-efficacy-of-emustil-drops-for-ocular-discomfort-and-tear-film-osmolarity-using-different-treatment-management-modes-under-dry-environmental-conditions
#3
JOURNAL ARTICLE
Ali Abusharha, E Ian Pearce, Tayyaba Afsar, Suhail Razak
BACKGROUND: We aimed to check the efficacy of Emustil (oil in water emulsion) drops on tear film index and ocular surface dynamics in dry environments through protection and relief treatment modalities. METHODS: The subjects were exposed to a dry environment using a Controlled Environment Chamber (CEC) where the relative humidity (RH) was 5% and the temperature was 21 °C and screened for ocular symptoms, tear osmolarity, ocular surface temperature (OST) and tear production using ocular Surface Disease Index questionnaire (OSDI), OcuSense TearLab Osmometer, FLIR System ThermaCAM P620 and Schirmer strips/phenol red test respectively...
March 25, 2024: BMC Ophthalmology
https://read.qxmd.com/read/38516415/central-hyperthyroidism-due-to-an-ectopic-tsh-secreting-pituitary-tumor-a-case-report-and-literature-review
#4
Chonggui Zhu, Tong Liu, Haonan Yu, Lina Chang, Xiaona Zhang, Jia Yao, Geng Zhang, Qiusong Chen, Qing He, Ming Liu
Ectopic thyroid-stimulating hormone (TSH)-secreting tumors are extremely rare, with only 15 reported cases in the literature. Herein, we described a 60-year-old female patient with thyrotoxicosis and elevated or unsuppressed levels of TSH. Family history and laboratory and genetic tests did not support a diagnosis of resistance to thyroid hormone (RTH). Given the unsuppressed TSH, TSH-secreting tumor was suspected, and magnetic resonance imaging (MRI) of the pituitary gland was performed. Surprisingly, the MRI scans revealed a nodule in the nasopharynx rather than a pituitary tumor in the sella region...
2024: Frontiers in Endocrinology
https://read.qxmd.com/read/38510411/observed-structured-teaching-experiences-ostes-in-a-students-as-teachers-course
#5
JOURNAL ARTICLE
Margaret R Mahoney, Matthew E Gayoso, Natasha A Belsky, Travis W Crook, Kendra P Parekh
INTRODUCTION: Teaching is an important competency in graduate medical education (GME). Many residency programs have implemented curricula to develop residents' teaching skills and observed structured teaching experiences (OSTEs) have been used to assess these skills. There is an increasing focus on building teaching skills earlier in the medical education continuum, however, there is limited literature on assessing medical students' teaching skills. The authors developed an OSTE for medical students enrolled in a students-as-teachers course to address this gap and provide formative feedback on teaching skills...
February 2024: Medical Science Educator
https://read.qxmd.com/read/38508239/cancer-specific-dose-and-fractionation-schedules-in-stereotactic-body-radiotherapy-for-oligometastatic-disease-an-interim-analysis-of-the-eortc-estro-e-2-radiate-oligocare-study
#6
JOURNAL ARTICLE
Sebastian M Christ, Filippo Alongi, Umberto Ricardi, Marta Scorsetti, Lorenzo Livi, Panagiotis Balermpas, Yolande Lievens, Pètra Braam, Barbara Alicja Jereczek-Fossa, Karin Stellamans, Ivica Ratosa, Joachim Widder, Heike Peulen, Piet Dirix, Samuel Bral, Sara Ramella, Hossein Hemmatazad, Kaouthar Khanfir, Xavier Geets, Paul Jeene, Thomas Zilli, Beatrice Fournier, Giovanni Battista Ivaldi, Enrico Clementel, Catherine Fortpied, Felix Boakye Oppong, Piet Ost, Matthias Guckenberger
BACKGROUND AND INTRODUCTION: Optimal dose and fractionation in stereotactic body radiotherapy (SBRT) for oligometastatic cancer patients remain unknown. In this interim analysis of OligoCare, we analyzed factors associated with SBRT dose and fractionation. MATERIALS AND METHODS: Analysis was based on the first 1,099 registered patients. SBRT doses were converted to biological effective doses (BED) using α/β of 10 Gy for all primaries, and cancer-specific α/β of 10 Gy for non-small cell lung and colorectal cancer (NSCLC, CRC), 2...
March 18, 2024: Radiotherapy and Oncology
https://read.qxmd.com/read/38497395/height-loss-in-postmenopausal-women-predicts-multiple-fractures-in-10-year-follow-up-results-from-the-rac-ost-pol-study
#7
JOURNAL ARTICLE
Wojciech Pluskiewicz, Piotr Adamczyk, Aleksandra Werner, Malgorzata Bach, Bogna Drozdzowska
INTRODUCTION: In daily practice the diagnostic process for osteoporosis in elderly patients should also include physical assessment. The aim of the study was to verify the hypothesis that height loss (HL) predicts fracture incidence. MATERIAL AND METHODS: The study was performed in an epidemiological sample of postmenopausal women recruited in the RAC-OST-POL study. At baseline, data were collected in 978 postmenopausal women at a mean age of 66.48±7.6 years, and at 10-year follow-up 640 patients remained, with a mean age of 75...
2024: Endokrynologia Polska
https://read.qxmd.com/read/38492010/efficacy-tolerability-and-safety-of-oral-sulfate-tablet-versus-2-l-polyethylene-glycol-ascorbate-for-bowel-preparation-in-older-patients-prospective-multicenter-investigator-single-blinded-randomized-study
#8
JOURNAL ARTICLE
Ho Suk Kang, Soo-Young Na, Jin Young Yoon, Yunho Jung, Geom Seog Seo, Jae Myung Cha
BACKGROUND: We compared the efficacy, tolerability, and safety of oral sulfate tablets (OST, which contains simethicone) and 2 L-polyethylene glycol/ascorbate (2 L-PEG/Asc) with a split-dosing regimen in older individuals aged ≥ 70 years who underwent scheduled colonoscopy. METHODS: This prospective, randomized, investigator-blinded, multicenter study was conducted between June 2022 and October 2023. Participants aged ≥ 70 years were randomized at a ratio of 1:1 to the OST or 2 L-PEG/Asc groups...
March 16, 2024: Journal of Gastroenterology
https://read.qxmd.com/read/38490228/systematic-endoscopic-staging-of-mediastinum-to-guide-radiotherapy-planning-in-patients-with-locally-advanced-non-small-cell-lung-cancer-seismic-an-international-multicentre-single-arm-clinical-trial
#9
JOURNAL ARTICLE
Daniel P Steinfort, Gargi Kothari, Neil Wallace, Nicholas Hardcastle, Kanishka Rangamuwa, Edith M T Dieleman, Percy Lee, Peixuan Li, Julie A Simpson, Shaun Yo, Farzad Bashirdazeh, Phan Nguyen, Barton R Jennings, David Fielding, Laurence Crombag, Louis B Irving, Kazuhiro Yasufuku, Jouke T Annema, David E Ost, Shankar Siva
BACKGROUND: Systematic mediastinal lymph node staging by endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) improves accuracy of staging in patients with early-stage non-small-cell lung cancer (NSCLC). However, patients with locally advanced NSCLC commonly undergo only selective lymph node sampling. This study aimed to determine the proportion of patients with locally advanced NSCLC in whom systematic endoscopic mediastinal staging identified PET-occult lymph node metastases, and to describe the consequences of PET-occult disease on radiotherapy planning...
March 11, 2024: Lancet Respiratory Medicine
https://read.qxmd.com/read/38488479/osteoinductive-dental-pulp-stem-cell-derived-extracellular-vesicle-loaded-multifunctional-hydrogel-for-bone-regeneration
#10
JOURNAL ARTICLE
Li Wang, Xinbo Wei, Xi He, Shengzhao Xiao, Qiusheng Shi, Peng Chen, Jesse Lee, Ximin Guo, Haifeng Liu, Yubo Fan
Stem cell-derived extracellular vesicles (EVs) show great potential for promoting bone tissue regeneration. However, normal EVs (Nor-EVs) have a limited ability to direct tissue-specific regeneration. Therefore, it is necessary to optimize the osteogenic capacity of EV-based systems for repairing extensive bone defects. Herein, we show that hydrogels loaded with osteoinductive dental pulp stem cell-derived EVs (Ost-EVs) enhanced bone tissue remodeling, resulting in a 2.23 ± 0.25-fold increase in the expression of bone morphogenetic protein 2 (BMP2) compared to the hydrogel control group...
March 15, 2024: ACS Nano
https://read.qxmd.com/read/38486197/acceptance-and-feasibility-of-a-low-threshold-and-substitution-services-based-periodical-monitoring-system-for-blood-borne-and-sexually%C3%A2-transmitted-infections-among-people-who-inject-drugs-in-germany-a-mixed-methods-analysis
#11
JOURNAL ARTICLE
Amrei Krings, Gyde Steffen, Ruth Zimmermann
BACKGROUND: To reach the global elimination goals of viral hepatitis B and C (HBC, HCV), human immunodeficiency virus (HIV) and other sexually transmitted infections as a public health threat by 2030, monitoring is needed. Staff members of drug services and opioid substitution treatment (OST) practices in Berlin and Bavaria recruited clients for a pilot study addressing the respective infections among people who injected drugs (PWID) in Germany, 2021/2022. Participants filled a questionnaire and were tested for HBV, HCV, HIV and syphilis using dried blood spots (DBS)...
March 14, 2024: Harm Reduction Journal
https://read.qxmd.com/read/38482166/corrigendum-examination-of-critical-factors-influencing-ruminant-disease-dynamics-in-the-black-sea-basin
#12
Margarida Arede, Daniel Beltrán-Alcrudo, Jeyhun Aliyev, Tengiz Chaligava, Ipek Keskin, Tigran Markosyan, Dmitry Morozov, Sarah Oste, Andrii Pavlenko, Mihai Ponea, Nicolae Starciuc, Anna Zdravkova, Eran Raizman, Jordi Casal, Alberto Allepuz
[This corrects the article DOI: 10.3389/fvets.2023.1174560.].
2024: Frontiers in Veterinary Science
https://read.qxmd.com/read/38472355/alkbh1-promotes-hif-1%C3%AE-mediated-glycolysis-by-inhibiting-n-glycosylation-of-lamp2a
#13
JOURNAL ARTICLE
Yanyan Liu, Mengmeng Li, Miao Lin, Xinjie Liu, Haolin Guo, Junyang Tan, Liubing Hu, Jianshuang Li, Qinghua Zhou
ALKBH1 is a typical demethylase of nucleic acids, which is correlated with multiple types of biological processes and human diseases. Recent studies are focused on the demethylation of ALKBH1, but little is known about its non-demethylase function. Here, we demonstrate that ALKBH1 regulates the glycolysis process through HIF-1α signaling in a demethylase-independent manner. We observed that depletion of ALKBH1 inhibits glycolysis flux and extracellular acidification, which is attributable to reduced HIF-1α protein levels, and it can be rescued by reintroducing HIF-1α...
March 12, 2024: Cellular and Molecular Life Sciences: CMLS
https://read.qxmd.com/read/38463026/optimized-sequential-therapy-vs-10-and-14-d-concomitant-therapy-for-eradicating-helicobacter-pylori-a-randomized-clinical-trial
#14
Hassan Seddik, Jihane Benass, Sanaa Berrag, Asmae Sair, Reda Berraida, Hanae Boutallaka
BACKGROUND: A cure for Helicobacter pylori ( H. pylori ) remains a problem of global concern. The prevalence of antimicrobial resistance is widely rising and becoming a challenging issue worldwide. Optimizing sequential therapy seems to be one of the most attractive strategies in terms of efficacy, tolerability and cost. The most common sequential therapy consists of a dual therapy [proton-pump inhibitors (PPIs) and amoxicillin] for the first period (5 to 7 d), followed by a triple therapy for the second period (PPI, clarithromycin and metronidazole)...
February 14, 2024: World Journal of Gastroenterology: WJG
https://read.qxmd.com/read/38461010/development-and-revision-of-meaningful-stage-descriptors-for-m1a-non-small-cell-lung-cancer
#15
EDITORIAL
David E Ost
No abstract text is available yet for this article.
March 2024: Chest
https://read.qxmd.com/read/38457371/impact-of-interkingdom-microbial-interactions-in-the-vaginal-tract
#16
JOURNAL ARTICLE
Shirli Cohen, Kyla S Ost, Kelly S Doran
No abstract text is available yet for this article.
March 2024: PLoS Pathogens
https://read.qxmd.com/read/38454839/quantitative-and-comparative-analysis-of-thermography-parameters-in-posterior-scleritis-choroiditis-and-controls
#17
JOURNAL ARTICLE
Ankush Kawali, Aayesha Khanum, Sai Bhakti Mishra, Srinivasan Sanjay, Padmamalini Mahendradas, Rohit Shetty
PURPOSE: To compare various ocular thermography parameters in posterior scleritis (PS), choroiditis (choroidal granuloma [CG], Vogt-Koyanagi-Harada [VKH] syndrome), central serous chorioretinopathy (CSCR), and healthy controls. METHODS: This retrospective, observational, comparative study evaluated cases undergoing ocular thermography between April 2017 and October 2023. The study groups included cases of PS, CG, and VKH, while the control group comprised CSCR cases and healthy individuals...
March 8, 2024: Indian Journal of Ophthalmology
https://read.qxmd.com/read/38445110/a-qualitative-exploration-of-ambulance-clinician-behaviour-and-decision-making-to-identify-factors-influencing-on-scene-times-for-suspected-stroke-patients-in-north-east-england
#18
JOURNAL ARTICLE
Abi Alton, Lisa Shaw, Tracy Finch, Christopher Price, Graham McClelland
AIMS/OBJECTIVES: Ambulance clinician assessment of suspected stroke patients aims to provide rapid access to specialist care, however regional and national data show increasing pre-hospital times. This study explored paramedic views about factors contributing to on-scene time (OST) for suspected stroke patients, with a view to identifying opportunities for future interventions, to reduce OST. METHODS: Views of paramedics from one regional service on factors influencing OST were explored using a qualitative approach...
March 1, 2024: British paramedic journal
https://read.qxmd.com/read/38437084/stainedsweeper-compact-variable-intensity-light-attenuation-display-with-sweeping-tunable-retarders
#19
JOURNAL ARTICLE
Yuichi Hiroi, Takefumi Hiraki, Yuta Itoh
Light Attenuation Displays (LADs) are a type of Optical See-Through Head-Mounted Display (OST-HMD) that present images by attenuating incoming light with a pixel-wise polarizing color filter. Although LADs can display images in bright environments, there is a trade-off between the number of Spatial Light Modulators (SLMs) and the color gamut and contrast that can be expressed, making it difficult to achieve both high-fidelity image display and a small form factor. To address this problem, we propose StainedSweeper, a LAD that achieves both the wide color gamut and the variable intensity with a single SLM...
March 4, 2024: IEEE Transactions on Visualization and Computer Graphics
https://read.qxmd.com/read/38430778/dietary-supplementation-of-osthole-and-icariin-improves-the-production-performance-of-laying-hens-by-promoting-follicular-development
#20
JOURNAL ARTICLE
Wenwen Ding, Linhui Shangguan, Hongquan Li, Yinghui Bao, Fida Noor, Abdul Haseeb, Panpan Sun, Hua Zhang, Wei Yin, Kuohai Fan, Huizhen Yang, Zhenbiao Zhang, Na Sun
Osthole (Ost) and icariin (Ica) are extracted from traditional Chinese medicine Cnidium monnieri and Epimedii Folium, respectively, and both exhibit estrogen-like biological activity. This study aimed to determine the efficacy and safety of combining Ost with Ica on the production performance of laying hens and to explore their possible mechanisms. The production performance, egg quality, residues of Ost and Ica in eggs, serum reproductive hormone levels, expression of ovarian reproductive hormone receptor, proliferation of granulosa cells in small yellow follicles (SYF), and progesterone secretion in large yellow follicles (LYF) related genes and proteins expression were detected...
February 22, 2024: Poultry Science
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