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Validity and reliability

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https://www.readbyqxmd.com/read/28655125/validation-of-the-korean-version-of-the-spinal-appearance-questionnaire
#1
Jung Sub Lee, Jong Ki Shin, Tae Sik Goh, Seung Min Son, Sung Jin An
OBJECTIVE: To evaluate the reliability and validity of an adapted Korean version of the Spinal Appearance Questionnaire (SAQ). METHODS: Translation/retranslation of the English version of the SAQ was conducted, and all steps of the cross-cultural adaptation process were performed. The Korean version of the SAQ (K-SAQ) and the previously validated appearance domain of the Korean version of the Scoliosis Research Society-22 Outcomes questionnaire (K-SRS-22) were mailed to 160 patients with adolescent idiopathic scoliosis (AIS)...
June 3, 2017: Journal of Back and Musculoskeletal Rehabilitation
https://www.readbyqxmd.com/read/28655060/biomarkers-and-surrogate-endpoints-in-uveitis-the-impact-of-quantitative-imaging
#2
Alastair K Denniston, Pearse A Keane, Sunil K Srivastava
Purpose: Uveitis is a major cause of sight loss across the world. The reliable assessment of intraocular inflammation in uveitis ('disease activity') is essential in order to score disease severity and response to treatment. In this review, we describe how 'quantitative imaging', the approach of using automated analysis and measurement algorithms across both standard and emerging imaging modalities, can develop objective instrument-based measures of disease activity. Methods: This is a narrative review based on searches of the current world literature using terms related to quantitative imaging techniques in uveitis, supplemented by clinical trial registry data, and expert knowledge of surrogate endpoints and outcome measures in ophthalmology...
May 1, 2017: Investigative Ophthalmology & Visual Science
https://www.readbyqxmd.com/read/28654868/simultaneous-assessment-of-absorption-characteristics-of-coumarins-from-angelicae-pubescentis-radix-in-vitro-transport-across-caco-2-cell-and-in-vivo-pharmacokinetics-in-rats-after-oral-administration
#3
Yan-Fang Yang, Lei Zhang, You-Bo Zhang, Xiu-Wei Yang
Angelicae Pubescentis Radix (APR), a well-known traditional Chinese medicine, is widely used for the treatments of rheumatism and headache for centuries. To assess the absorption characteristics of coumarins from APR, a sensitive and reliable UPLC-MS/MS method was established for the simultaneous determination of sixteen coumarins from APR, including psoralen, xanthotoxin, bergapten, bergaptol, isoimperatorin, imperatorin, columbianetin, columbianetin acetate, columbianadin, oxypeucedanin hydrate, angelol B, umbelliferone, scopoletin, osthole, meranzin hydrate and nodakenetin...
June 13, 2017: Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences
https://www.readbyqxmd.com/read/28654646/developing-and-validating-a-scale-to-measure-food-and-nutrition-literacy-fnlit-in-elementary-school-children-in-iran
#4
Aazam Doustmohammadian, Nasrin Omidvar, Nastaran Keshavarz-Mohammadi, Morteza Abdollahi, Maryam Amini, Hassan Eini-Zinab
BACKGROUND: Food and nutrition literacy is an emerging term which is increasingly used in policy and research. Though research in this area is growing, progression is limited by the lack of an accepted method to measure food and nutrition literacy. The aim of this study is to develop a valid and reliable questionnaire to assess food and nutrition literacy in elementary school children in the city of Tehran. METHODS: The study was conducted in three phases. To develop Food and Nutrition Literacy (FNLIT) questionnaire, a comprehensive literature review and a qualitative study were initially performed to identify food and nutrition literacy dimensions and its components...
2017: PloS One
https://www.readbyqxmd.com/read/28654600/an-appraisal-of-the-cephalic-index-in-sagittal-craniosynostosis-and-the-unseen-third-dimension
#5
Jeffrey A Fearon, Kanlaya Ditthakasem, Morley Herbert, John Kolar
BACKGROUND: The cephalic index is often used to evaluate sagittal craniosynostosis corrections; however, validation of this measure remains untested. METHODS: A three-part study was designed to (1) determine the normal distribution of cephalic indices in untreated sagittal craniosynostosis; (2) examine index values in treated children, subsequently determined to require secondary surgery; and (3) explore the correlation between a photography-based assessment of scaphocephaly severity and the cephalic index...
July 2017: Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/28654569/maintaining-interrater-agreement-of-core-assessment-instruments-in-a-multisite-randomized-controlled-clinical-trial-the-randomized-evaluation-of-sedation-titration-for-respiratory-failure-restore-trial
#6
Ruth Lebet, Jennifer Hayakawa, Tracy B Chamblee, Joana A Tala, Nakul Singh, David Wypij, Martha A Q Curley
BACKGROUND: RESTORE (Randomized Evaluation of Sedation Titration for Respiratory Failure) was a cluster randomized clinical trial evaluating a sedation strategy in children 2 weeks to <18 years of age with acute respiratory failure supported on mechanical ventilation. A total of 31 U.S. pediatric intensive care units (PICUs) participated in the trial. Staff nurse rater agreement on measures used to assess a critical component of treatment fidelity was essential throughout the 4-year data collection period...
July 2017: Nursing Research
https://www.readbyqxmd.com/read/28654495/commentary-on-reliability-and-validity-of-the-50-ft-walk-test-for-idiopathic-toe-walking
#7
Chelsea R Luck, Nancy B Muir
No abstract text is available yet for this article.
July 2017: Pediatric Physical Therapy
https://www.readbyqxmd.com/read/28654494/reliability-and-validity-of-the-50-ft-walk-test-for-idiopathic-toe-walking
#8
Catie Christensen, Amanda Haddad, Elizabeth Maus
PURPOSE: To evaluate interrater reliability and concurrent validity of the 50-ft walk test (FWT) for children with idiopathic toe walking (ITW). METHODS: Thirty children, 6 to 13 years old, with ITW participated. During the 50-FWT, an accelerometer counted total steps. A physical therapist counted the number of toe-walking steps. The number of toe-walking steps was divided by the total steps to calculate a toe-walking percentage. Interrater reliability was assessed by correlating the toe-walking percentage obtained by 2 raters using an intraclass correlation coefficient...
July 2017: Pediatric Physical Therapy
https://www.readbyqxmd.com/read/28654314/cross-validation-of-a-glucose-insulin-glucagon-pharmacodynamics-model-for-simulation-using-data-from-patients-with-type-1-diabetes
#9
Sabrina Lyngbye Wendt, Ajenthen Ranjan, Jan Kloppenborg Møller, Signe Schmidt, Carsten Boye Knudsen, Jens Juul Holst, Sten Madsbad, Henrik Madsen, Kirsten Nørgaard, John Bagterp Jørgensen
BACKGROUND: Currently, no consensus exists on a model describing endogenous glucose production (EGP) as a function of glucagon concentrations. Reliable simulations to determine the glucagon dose preventing or treating hypoglycemia or to tune a dual-hormone artificial pancreas control algorithm need a validated glucoregulatory model including the effect of glucagon. METHODS: Eight type 1 diabetes (T1D) patients each received a subcutaneous (SC) bolus of insulin on four study days to induce mild hypoglycemia followed by a SC bolus of saline or 100, 200, or 300 µg of glucagon...
February 1, 2017: Journal of Diabetes Science and Technology
https://www.readbyqxmd.com/read/28653978/transdiagnostic-clinical-global-impression-scoring-for-routine-clinical-settings
#10
Boadie W Dunlop, Jaclyn Gray, Mark H Rapaport
Although there is great interest in the improving the ability to track patients' change over time in routine clinical care settings, no standardized transdiagnostic measure is currently available for busy clinicians to apply. The Clinical Global Impression (CGI) scales are simple measures widely used as outcomes in psychiatric clinical trials. However, the CGI suffers from poorly defined scoring anchors. Efforts to improve the anchors by enhancing the anchor descriptions have proven useful but are limited by being disease-specific, thereby acting as a barrier to the routine clinical adoption of the CGI...
June 27, 2017: Behavioral Sciences
https://www.readbyqxmd.com/read/28653703/pitfalls-in-metal-organic-framework-crystallography-towards-more-accurate-crystal-structures
#11
S Øien-Ødegaard, G C Shearer, D S Wragg, K P Lillerud
Single crystal X-ray diffraction (SC-XRD) is the principal method for determining the crystal structures of metal-organic frameworks (MOFs). This tutorial deals with the handling of MOF crystals and analysis of crystallographic data obtained from single-crystal X-ray diffraction, focusing on two features that are particularly important in MOF crystallography and have a large impact on the quality and reliability of the final crystal structures: (1) the treatment of pore-occupying entities (both in the physical crystals and in the crystallographic model) and (2) crystallographic twinning...
June 27, 2017: Chemical Society Reviews
https://www.readbyqxmd.com/read/28653560/difficulties-in-comprehending-affirmative-and-negative-sentences-evidence-from-chinese-children-with-reading-difficulties
#12
Shenai Hu, Maria Vender, Gaetano Fiorin, Denis Delfitto
Recent experimental results suggest that negation is particularly challenging for children with reading difficulties. This study looks at how young poor readers, speakers of Mandarin Chinese, comprehend affirmative and negative sentences as compared with a group of age-matched typical readers. Forty-four Chinese children were tested with a truth value judgment task. The results reveal that negative sentences were harder to process than affirmative ones, irrespective of the distinction between poor and typical readers...
June 1, 2017: Journal of Learning Disabilities
https://www.readbyqxmd.com/read/28653547/assessment-of-mood-in-aphasia-following-stroke-validation-of-the-dynamic-visual-analogue-mood-scales-d-vams
#13
Paul D Barrows, Shirley A Thomas
OBJECTIVES: To validate a non-verbal self-report measure of mood - the Dynamic Visual Analogue Mood Scales (D-VAMS) - against the Hospital Anxiety and Depression Scale (HADS) and assess its suitability as an outcome measure or screening measure for depressed mood following stroke. DESIGN: Cross-sectional observational cohort study. PARTICIPANTS: Forty-six stroke survivors (24% with aphasia) recruited from online, from stroke clubs and via an NHS rehabilitation service...
June 1, 2017: Clinical Rehabilitation
https://www.readbyqxmd.com/read/28653259/a-medication-assessment-tool-to-evaluate-prescribers-adherence-to-evidence-based-guidelines-in-bipolar-disorder
#14
Dalal M Al-Taweel, Mohammad Alsuwaidan
Background The goal of evidence-based clinical practice has led to an increased interest in the development of tools to measure adherence to national guidelines in different diseases. This aids in detecting and measuring inappropriate prescribing to specific patient groups by using quality standards extracted from evidence-based guidelines, and ultimately provide the basis of consistent standardized prescribing. Objective To design and validate a medication assessment tool to assess prescribers' adherence to international guideline recommendations in the management of bipolar disorder (MATBD)...
June 26, 2017: International Journal of Clinical Pharmacy
https://www.readbyqxmd.com/read/28653035/a-classification-algorithm-for-predicting-progression-from-normal-cognition-to-mild-cognitive-impairment-across-five-cohorts-the-preclinical-ad-consortium
#15
Alden L Gross, Jason J Hassenstab, Sterling C Johnson, Lindsay R Clark, Susan M Resnick, Melissa Kitner-Triolo, Colin L Masters, Paul Maruff, John C Morris, Anja Soldan, Corinne Pettigrew, Marilyn S Albert
INTRODUCTION: We established a method for diagnostic harmonization across multiple studies of preclinical Alzheimer's disease and validated the method by examining its relationship with clinical status and cognition. METHODS: Cognitive and clinical data were used from five studies (N = 1746). Consensus diagnoses established in each study used criteria to identify progressors from normal cognition to mild cognitive impairment. Correspondence was evaluated between these consensus diagnoses and three algorithmic classifications based on (1) objective cognitive impairment in 2+ tests only; (2) a Clinical Dementia Rating (CDR) of ≥0...
2017: Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring
https://www.readbyqxmd.com/read/28652924/usefulness-of-limited-sampling-strategy-for-mycophenolic-acid-area-under-the-curve-considering-postoperative-days-in-living-donor-renal-transplant-recipients-with-concomitant-prolonged-release-tacrolimus
#16
Tomoyuki Enokiya, Kouhei Nishikawa, Yuichi Muraki, Takuya Iwamoto, Hideki Kanda, Yoshiki Sugimura, Masahiro Okuda
BACKGROUND: The optimal dose of mycophenolate mofetil (MMF) in renal transplant patients has been recommended to be decided on the basis of area under the concentration-time curve (AUC0-12) of mycophenolic acid (MPA). Although meta-analysis has revealed that postoperative day (POD) is an influencing factor in MPA pharmacokinetics, there are no reports regarding a limited sampling strategy (LSS) for MPA AUC in consideration of POD. The aim of this study was to construct of an LSS considering POD that appropriately expresses the MPA AUC following renal transplantation and evaluation of the usefulness...
2017: Journal of Pharmaceutical Health Care and Sciences
https://www.readbyqxmd.com/read/28652836/initial-development-of-a-patient-reported-outcome-measure-of-experience-with-cognitive-impairment-associated-with-schizophrenia
#17
Lisa C Welch, Jeremiah J Trudeau, Steven M Silverstein, Michael Sand, David C Henderson, Raymond C Rosen
Cognitive impairment is a serious, often distressing aspect of schizophrenia that affects patients' day-to-day lives. Although several interview-based instruments exist to assess cognitive functioning, a reliable measure developed based on the experiences of patients facing cognitive difficulties is needed to complement the objective performance-based assessments. The present article describes the initial development of a patient-reported outcome (PRO) measure to assess the subjective experience of cognitive impairment among patients with schizophrenia, the Patient-Reported Experience of Cognitive Impairment in Schizophrenia (PRECIS)...
2017: Patient related Outcome Measures
https://www.readbyqxmd.com/read/28652835/a-randomized-controlled-trial-to-validate-the-alice-pdx-ambulatory-device
#18
Georg Nilius, Ulrike Domanski, Maik Schroeder, Karl-Josef Franke, Anke Hogrebe, Laurent Margarit, Maria Stoica, Marie-Pia d'Ortho
BACKGROUND: Obstructive sleep apnea (OSA) is a highly prevalent condition; however, the majority of patients remain undiagnosed. There is a potential to expand the diagnostic capacity of sleep laboratories. The study objective was to validate a portable respiratory monitoring device (Alice PDX) against polysomnography (PSG) in the laboratory and to assess its reliability at home. METHODS: A total of 85 patients with suspected OSA (80% male, mean age 49.1±13.5 years, body mass index 29...
2017: Nature and Science of Sleep
https://www.readbyqxmd.com/read/28652724/palliative-care-and-prognosis-in-copd-a-systematic-review-with-a-validation-cohort
#19
Pere Almagro, Sergi Yun, Ana Sangil, Mónica Rodríguez-Carballeira, Meritxell Marine, Pedro Landete, Juan José Soler-Cataluña, Joan B Soriano, Marc Miravitlles
Current recommendations to consider initiation of palliative care (PC) in COPD patients are often based on an expected poor prognosis. However, this approach is not evidence-based, and which and when COPD patients should start PC is controversial. We aimed to assess whether current suggested recommendations for initiating PC were sufficiently reliable. We identified prognostic variables proposed in the literature for initiating PC; then, we ascertained their relationship with 1-year mortality, and finally, we validated their utility in our cohort of 697 patients hospitalized for COPD exacerbation...
2017: International Journal of Chronic Obstructive Pulmonary Disease
https://www.readbyqxmd.com/read/28652474/rapid-screening-of-primary-aldosteronism-by-a-novel-chemiluminescent-immunoassay
#20
Ryo Morimoto, Yoshikiyo Ono, Yuta Tezuka, Masataka Kudo, Sachiko Yamamoto, Toshiaki Arai, Celso E Gomez-Sanchez, Hironobu Sasano, Sadayoshi Ito, Fumitoshi Satoh
Measurement of plasma aldosterone and renin concentration, or activity, is useful for selecting antihypertensive agents and detecting hyperaldosteronism in hypertensive patients. However, it takes several days to get results when measured by radioimmunoassay and development of more rapid assays has been long expected. We have developed chemiluminescent enzyme immunoassays enabling the simultaneous measurement of both aldosterone and renin concentrations in 10 minutes by a fully automated assay using antibody-immobilized magnetic particles with quick aggregation and dispersion...
June 26, 2017: Hypertension
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