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Validity and reliability

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https://www.readbyqxmd.com/read/28454067/assessment-of-the-swat-model-to-simulate-a-watershed-with-limited-available-data-in-the-pampas-region-argentina
#1
Martín Romagnoli, Margarita Portapila, Alfredo Rigalli, Gisela Maydana, Martín Burgués, Carlos M García
Argentina has been among the world leaders in the production and export of agricultural products since the 1990s. The Carcarañá River Lower Basin (CRLB), a cropland of the Pampas region supplied by extensive rainfall, is located in an area with few streamgauging and other hydrologic/water-quality stations. Therefore, limited hydrologic data are available resulting in limited water-resources assessment. This work explores the application of Soil and Water Assessment Tool (SWAT) model to the CRLB in the Santa Fe province of the Pampas region...
April 25, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28453724/a-generative-angular-model-of-protein-structure-evolution
#2
Michael Golden, Eduardo Garcia-Portugues, Michael Sørensen, Kanti V Mardia, Thomas Hamelryck, Jotun Hein
Recently described stochastic models of protein evolution have demonstrated that the inclusion of structural information in addition to amino acid sequences leads to a more reliable estimation of evolutionary parameters. We present a generative, evolutionary model of protein structure and sequence that is valid on a local length scale. The model concerns the local dependencies between sequence and structure evolution in a pair of homologous proteins. The evolutionary trajectory between the two structures in the protein pair is treated as a random walk in dihedral angle space, which is modeled using a novel angular diffusion process on the two-dimensional torus...
April 27, 2017: Molecular Biology and Evolution
https://www.readbyqxmd.com/read/28453640/pioneering-topological-methods-for-network-based-drug-target-prediction-by-exploiting-a-brain-network-self-organization-theory
#3
Claudio Durán, Simone Daminelli, Josephine M Thomas, V Joachim Haupt, Michael Schroeder, Carlo Vittorio Cannistraci
The bipartite network representation of the drug-target interactions (DTIs) in a biosystem enhances understanding of the drugs' multifaceted action modes, suggests therapeutic switching for approved drugs and unveils possible side effects. As experimental testing of DTIs is costly and time-consuming, computational predictors are of great aid. Here, for the first time, state-of-the-art DTI supervised predictors custom-made in network biology were compared-using standard and innovative validation frameworks-with unsupervised pure topological-based models designed for general-purpose link prediction in bipartite networks...
April 26, 2017: Briefings in Bioinformatics
https://www.readbyqxmd.com/read/28453583/-validation-of-the-successful-aging-inventory-in-chilean-older-people
#4
Lorena Gallardo-Peralta, Alejandro Cuadra-Peralta, Ximena Cámara-Rojo, Betty Gaspar-Delpino, Renato Sánchez-Lillo
BACKGROUND: There is a paucity of adequate and validated instruments for the measurement of successful aging for geriatric researchers in Chile. AIM: To validate the “Successful Aging Inventory” (SAI) in Chilean older people. MATERIAL AND METHODS: SAI was answered by 777 older people aged 70 ± 7 years (63% women) living in urban and rural areas, including the highlands of a Northern desert region of Chile. RESULTS: A Cronbach alfa of 0...
February 2017: Revista Médica de Chile
https://www.readbyqxmd.com/read/28453573/how-reliable-and-valid-is-the-teacher-version-of-the-strengths-and-difficulties-questionnaire-in-primary-school-children
#5
Meta van den Heuvel, Danielle E M C Jansen, Roy E Stewart, Bouwien C M Smits-Engelsman, Sijmen A Reijneveld, Boudien C T Flapper
INTRODUCTION: The Strengths and Difficulties Questionnaire (SDQ) is validated for parents, but not yet for teachers in a broad age range of children. We conducted a cross-sectional study with 4-10 years old school children to investigate if the SDQ-T can be used instead of the validated but lengthy Teacher's Report Form (TRF) to acquire information about emotional and behavioral problems in the school community. METHODS: Teachers of 453 children from primary schools were approached...
2017: PloS One
https://www.readbyqxmd.com/read/28453544/predicting-herbivore-faecal-nitrogen-using-a-multispecies-near-infrared-reflectance-spectroscopy-calibration
#6
Miriam Villamuelas, Emmanuel Serrano, Johan Espunyes, Néstor Fernández, Jorge R López-Olvera, Mathieu Garel, João Santos, María Ángeles Parra-Aguado, Maurizio Ramanzin, Xavier Fernández-Aguilar, Andreu Colom-Cadena, Ignasi Marco, Santiago Lavín, Jordi Bartolomé, Elena Albanell
Optimal management of free-ranging herbivores requires the accurate assessment of an animal's nutritional status. For this purpose 'near-infrared reflectance spectroscopy' (NIRS) is very useful, especially when nutritional assessment is done through faecal indicators such as faecal nitrogen (FN). In order to perform an NIRS calibration, the default protocol recommends starting by generating an initial equation based on at least 50-75 samples from the given species. Although this protocol optimises prediction accuracy, it limits the use of NIRS with rare or endangered species where sample sizes are often small...
2017: PloS One
https://www.readbyqxmd.com/read/28453515/reliable-reference-genes-for-normalization-of-gene-expression-data-in-tea-plants-camellia-sinensis-exposed-to-metal-stresses
#7
Ming-Le Wang, Qing-Hui Li, Hua-Hong Xin, Xuan Chen, Xu-Jun Zhu, Xing-Hui Li
Tea plants [Camellia sinensis (L.) O. Kuntze] are an important leaf-type crop that are widely used for the production of non-alcoholic beverages in the world. Exposure to excessive amounts of heavy metals adversely affects the quality and yield of tea leaves. To analyze the molecular responses of tea plants to heavy metals, a reliable quantification of gene expression is important and of major importance herein is the normalization of the measured expression levels for the target genes. Ideally, stably expressed reference genes should be evaluated in all experimental systems...
2017: PloS One
https://www.readbyqxmd.com/read/28453500/rasch-derived-teachers-emotions-questionnaire
#8
Kristin L K Koskey, Renee R Mudrey, Wondimu Ahmed
The purpose of this research was to estimate the reliability of the scores produced from and validity of the inferences drawn from the revised 90-item Teachers' Emotion Questionnaire consisting of three measures: frequency of emotional expressivity, self-efficacy for regulation of emotional expressivity when teaching, and self-efficacy for regulation of context-specific emotional expressivity. A void exists in an instrument assessing teachers' regulation and communication of their emotions. One-hundred seventeen practicing teachers participated in this study at Time 1 and 46 at Time 2...
2017: Journal of Applied Measurement
https://www.readbyqxmd.com/read/28453497/rasch-analysis-of-a-behavioral-checklist-for-the-assessment-of-pain-in-critically-ill-adults
#9
Christophe Chenier, Gilles Raiche, Nadine Talbot, Bianca Carignan, Celine Gelinas
Patients hospitalized in the intensive care unit (ICU) are often unable to report their pain, which is a problem since untreated pain is associated with negative health outcomes. The use of behavioral pain scales are recommended for the detection of the presence of pain in this vulnerable population. Previous validation studies have used classical techniques, and several psychometrics properties remain unknown. In this paper, data obtained from a behavioral checklist of dichotomized items was utilized to evaluate the instrument's dimensionality, its construct validity and its capacity to distinguish between levels of pain by using Rasch measurement...
2017: Journal of Applied Measurement
https://www.readbyqxmd.com/read/28449331/mir-130a-as-a-diagnostic-marker-to-differentiate-malignant-mesothelioma-from-lung-adenocarcinoma-in-pleural-effusion-cytology
#10
Rocco Cappellesso, Marco Galasso, Lorenzo Nicolè, Paolo Dabrilli, Stefano Volinia, Ambrogio Fassina
BACKGROUND: Malignant pleural mesothelioma is a rare tumor with a dismal prognosis, usually presenting with recurrent effusions. However, the majority of malignant pleural effusions are due to lung adenocarcinoma (AdC). The distinction between these tumors has considerable therapeutic and medicolegal implications and can be very challenging both histologically and cytologically. Appropriate immunohistochemistry (IHC) is required to support the diagnosis. MicroRNA (miRNA) expression analysis could be a viable diagnostic tool for distinguishing between these tumors...
April 27, 2017: Cancer
https://www.readbyqxmd.com/read/28449235/psychometric-properties-of-the-mental-health-and-social-inadaptation-assessment-for-adolescents-mia-in-a-population-based-sample
#11
Sylvana M Côté, Massimiliano Orri, Mara Brendgen, Frank Vitaro, Michel Boivin, Christa Japel, Jean R Séguin, Marie-Claude Geoffroy, Alexandra Rouquette, Bruno Falissard, Richard E Tremblay
We report on the psychometric properties of the Mental Health and Social Inadaptation Assessment for Adolescents (MIA), a self-report instrument for quantifying the frequency of mental health and psychosocial adaptation problems using a dimensional approach and based on the DSM-5. The instrument includes 113 questions, takes 20-25 minutes to answer, and covers the past 12 months. A population-based cohort of adolescents (n = 1443, age = 15 years; 48% males) rated the frequency at which they experienced symptoms of Attention Deficit Hyperactivity Disorder (ADHD), Conduct Disorder, Oppositional Defiant Disorder, Depression, Generalized Anxiety, Social Phobia, Eating Disorders (i...
April 27, 2017: International Journal of Methods in Psychiatric Research
https://www.readbyqxmd.com/read/28449033/response-assessment-in-medulloblastoma-and-leptomeningeal-seeding-tumors-recommendations-from-the-response-assessment-in-pediatric-neuro-oncology-committee
#12
Katherine E Warren, Gilbert Vezina, Tina Y Poussaint, Monika Warmuth-Metz, Marc C Chamberlain, Roger J Packer, Alba A Brandes, Moshe Reiss, Stewart Goldman, Michael J Fisher, Ian F Pollack, Michael D Prados, Patrick Y Wen, Susan M Chang, Christelle Dufour, David Zurakowski, Rolf D Kortmann, Mark W Kieran
Lack of standard response criteria in clinical trials for medulloblastoma and other seeding tumors complicates assessment of therapeutic efficacy and comparisons across studies. An international working group was established to develop consensus recommendations for response assessment. The aim is that these recommendations be prospectively evaluated in clinical trials, with the goal of achieving more reliable risk stratification and uniformity across clinical trials. Current practices and literature review were performed to identify major confounding issues and justify subsequently developed recommendations; in areas lacking scientific investigations, recommendations were based on experience of committee members and consensus was reached after discussion...
April 25, 2017: Neuro-oncology
https://www.readbyqxmd.com/read/28448800/assessment-of-bilingual-children-what-if-testing-both-languages-is-not-possible
#13
Tessel Boerma, Elma Blom
Language delays of bilingual children can arise from language impairment (LI) but also from insufficient exposure to the target language. A reliable diagnosis of LI in bilingual children is therefore ideally based on the evaluation of both languages, as LI affects each language that is learned. However, due to the multitude of language combinations that are encountered in clinical practice, this is often not feasible. Bilingual norm-referencing may offer a solution, but the heterogeneity within the bilingual population makes it difficult to determine appropriate standards for every child...
April 10, 2017: Journal of Communication Disorders
https://www.readbyqxmd.com/read/28448375/promis-sleep-disturbance-and-sleep-related-impairment-in-adolescents-examining-psychometrics-using-self-report-and-actigraphy
#14
Alyson E Hanish, Deborah C Lin-Dyken, Joan C Han
BACKGROUND: The National Institutes of Health Patient-Reported Outcomes Measurement Information System (PROMIS) has self-reported health measures available for both pediatric and adult populations, but no pediatric measures are available currently in the sleep domains. OBJECTIVE: The purpose of this observational study was to perform preliminary validation studies on age-appropriate, self-reported sleep measures in healthy adolescents. METHODS: This study examined 25 healthy adolescents' self-reported daytime sleepiness, sleep disturbance, sleep-related impairment, and sleep patterns...
May 2017: Nursing Research
https://www.readbyqxmd.com/read/28448234/leveraging-clinical-imaging-archives-for-radiomics-reliability-of-automated-methods-for-brain-volume-measurement
#15
Viraj R Adduru, Andrew M Michael, Maria Helguera, Stefi A Baum, Gregory J Moore
Purpose To validate the use of thick-section clinically acquired magnetic resonance (MR) imaging data for estimating total brain volume (TBV), gray matter (GM) volume (GMV), and white matter (WM) volume (WMV) by using three widely used automated toolboxes: SPM ( www.fil.ion.ucl.ac.uk/spm/ ), FreeSurfer ( surfer.nmr.mgh.harvard.edu ), and FSL (FMRIB software library; Oxford Centre for Functional MR Imaging of the Brain, Oxford, England, https://fsl.fmrib.ox.ac.uk/fsl ). Materials and Methods MR images from a clinical archive were used and data were deidentified...
April 27, 2017: Radiology
https://www.readbyqxmd.com/read/28448228/preliminary-psychometric-properties-of-the-verbal-and-nonverbal-interaction-scale-an-observational-measure-for-communication-in-persons-with-dementia
#16
Christine L Williams, David Newman, Lena Marmstål Hammar
Little attention has been given to sociable/unsociable communication in persons with dementia despite the importance of these behaviors in maintaining engagement in marital relationships. An observational measure of verbal and nonverbal communication in persons with dementia (Verbal and Nonverbal Interaction Scale-CR) who were engaged in conversations with spouses was tested for reliability and validity. Married persons with dementia were video-recorded at home conversing with spouses over 10 weeks (N = 118 recordings)...
May 2017: Issues in Mental Health Nursing
https://www.readbyqxmd.com/read/28447827/interpersonal-dysfunction-in-personality-disorders-a-meta-analytic-review
#17
Sylia Wilson, Catherine B Stroud, C Emily Durbin
Personality disorders are defined in the current psychiatric diagnostic system as pervasive, inflexible, and stable patterns of thinking, feeling, behaving, and interacting with others. Questions regarding the validity and reliability of the current personality disorder diagnoses prompted a reconceptualization of personality pathology in the most recent edition of the psychiatric diagnostic manual, in an appendix of emerging models for future study. To evaluate the construct and discriminant validity of the current personality disorder diagnoses, we conducted a quantitative synthesis of the existing empirical research on associations between personality disorders and interpersonal functioning, defined using the interpersonal circumplex model (comprising orthogonal dimensions of agency and communion), as well as functioning in specific relationship domains (parent-child, family, peer, romantic)...
April 27, 2017: Psychological Bulletin
https://www.readbyqxmd.com/read/28447132/high-throughput-analysis-of-sub-visible-mab-aggregate-particles-using-automated-fluorescence-microscopy-imaging
#18
Albert Jesuran Paul, Fabian Bickel, Martina Röhm, Lisa Hospach, Bettina Halder, Nina Rettich, René Handrick, Eva Maria Herold, Hans Kiefer, Friedemann Hesse
Aggregation of therapeutic proteins is a major concern as aggregates lower the yield and can impact the efficacy of the drug as well as the patient's safety. It can occur in all production stages; thus, it is essential to perform a detailed analysis for protein aggregates. Several methods such as size exclusion high-performance liquid chromatography (SE-HPLC), light scattering, turbidity, light obscuration, and microscopy-based approaches are used to analyze aggregates. None of these methods allows determination of all types of higher molecular weight (HMW) species due to a limited size range...
April 27, 2017: Analytical and Bioanalytical Chemistry
https://www.readbyqxmd.com/read/28446960/primary-care-screening-questionnaire-for-depression-reliability-and-validity-of-a-new-four-item-tool
#19
Pillaveetil Sathyadas Indu, Thekkethayyil Viswanathan Anilkumar, Ramdas Pisharody, Paul Swamidhas Sudhakar Russell, Damodaran Raju, P Sankara Sarma, Saradamma Remadevi, K R Leela Itty Amma, A Sheelamoni, Chittaranjan Andrade
BACKGROUND: Unidentified depression in primary care is a public health concern, globally. There is a need for brief, valid and easily administered tools in primary care. AIMS: To estimate reliability and validity of the newly developed Primary care Screening Questionnaire for Depression (PSQ4D), a four-item tool, with 'yes' or 'no' options. METHOD: PSQ4D was administered verbally (time required, <1 min) by primary care physicians to adult outpatients (n=827) in six primary care settings in Kerala, India...
March 2017: BJPsych Open
https://www.readbyqxmd.com/read/28446893/construction-and-validation-of-the-perceived-opportunity-to-craft-scale
#20
Jessica van Wingerden, Irene M W Niks
We developed and validated a scale to measure employees' perceived opportunity to craft (POC) in two separate studies conducted in the Netherlands (total N = 2329). POC is defined as employees' perception of their opportunity to craft their job. In Study 1, the perceived opportunity to craft scale (POCS) was developed and tested for its factor structure and reliability in an explorative way. Study 2 consisted of confirmatory analyses of the factor structure and reliability of the scale as well as examination of the discriminant and criterion-related validity of the POCS...
2017: Frontiers in Psychology
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