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Validity and reliability

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https://www.readbyqxmd.com/read/28550720/development-and-validation-of-an-uplc-uv-method-for-determination-of-a-novel-triazine-coccidiostat-ethanamizuril-and-its-metabolite-m3-in-chicken-tissues
#1
Xiao Zhao, Youfa Xu, Lifang Zhang, Chunmei Wang, Chunna Guo, Chenzhong Fei, Keyu Zhang, Xiaoyang Wang, Yingchun Liu, Mi Wang, Wenli Zheng, Feiqun Xue
Ethanamizuril (EZL) is a novel anti-coccidial triazine synthesized by the Shanghai Veterinary Research Institute of the Chinese Academy of Agricultural Sciences. As a novel coccidiostat, it is essential to study its residue in food animal tissues. In this study, a reliable UPLC method for the determination of ethanamizuril (EZL) and one of its metabolites (M3) in chicken muscle, skin and fat, liver, and kidney samples was developed. Analytes were extracted using acetonitrile and 10% sodium carbonate solution, defatted by n-hexane, and further purified by using an Oasis MCX cartridge...
May 11, 2017: Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences
https://www.readbyqxmd.com/read/28550656/the-combined-use-of-virtual-reality-and-eeg-to-study-language-processing-in-naturalistic-environments
#2
Johanne Tromp, David Peeters, Antje S Meyer, Peter Hagoort
When we comprehend language, we often do this in rich settings where we can use many cues to understand what someone is saying. However, it has traditionally been difficult to design experiments with rich three-dimensional contexts that resemble our everyday environments, while maintaining control over the linguistic and nonlinguistic information that is available. Here we test the validity of combining electroencephalography (EEG) and virtual reality (VR) to overcome this problem. We recorded electrophysiological brain activity during language processing in a well-controlled three-dimensional virtual audiovisual environment...
May 26, 2017: Behavior Research Methods
https://www.readbyqxmd.com/read/28550413/glottal-gap-tracking-by-a-continuous-background-modeling-using-inpainting
#3
Gustavo Andrade-Miranda, Juan Ignacio Godino-Llorente
The visual examination of the vibration patterns of the vocal folds is an essential method to understand the phonation process and diagnose voice disorders. However, a detailed analysis of the phonation based on this technique requires a manual or a semi-automatic segmentation of the glottal area, which is difficult and time consuming. The present work presents a cuasi-automatic framework to accurately segment the glottal area introducing several techniques not explored before in the state of the art. The method takes advantage of the possibility of a minimal user intervention for those cases where the automatic computation fails...
May 27, 2017: Medical & Biological Engineering & Computing
https://www.readbyqxmd.com/read/28550275/detection-of-small-bowel-tumor-in-wireless-capsule-endoscopy-images-using-an-adaptive-neuro-fuzzy-inference-system
#4
Alizadeh Mahdi, Haji Maghsoudi Omid, Sharzehi Kaveh, Reza Hemati Hamid, Kamali Asl Alireza, Talebpour Alireza
Automatic diagnosis tool helps physicians to evaluate capsule endoscopic examinations faster and more accurate. The purpose of this study was to evaluate the validity and reliability of an automatic post-processing method for identifying and classifying wireless capsule endoscopic images, and investigate statistical measures to differentiate normal and abnormal images. The proposed technique consists of two main stages, namely, feature extraction and classification. Primarily, 32 features incorporating four statistical measures (contrast, correlation, homogeneity and energy) calculated from co-occurrence metrics were computed...
May 26, 2017: Journal of Biomedical Research
https://www.readbyqxmd.com/read/28550032/a-predictive-score-for-thrombosis-associated-with-breast-colorectal-lung-or-ovarian-cancer-the-prospective-compass-cancer-associated-thrombosis-study
#5
Grigoris T Gerotziafas, Ali Taher, Hikmat Abdel-Razeq, Essam AboElnazar, Alex C Spyropoulos, Salem El Shemmari, Annette K Larsen, Ismail Elalamy
BACKGROUND: The stratification of outpatients on chemotherapy for breast, colorectal, lung, and ovarian cancers at risk of venous thromboembolism (VTE) remains an unmet clinical need. The derivation of a risk assessment model (RAM) for VTE in these patients was the aim of the study "Prospective Comparison of Methods for thromboembolic risk assessment with clinical Perceptions and AwareneSS in real life patients-Cancer Associated Thrombosis" (COMPASS-CAT). PATIENTS AND METHODS: The derivation cohort consisted of 1,023 outpatients...
May 26, 2017: Oncologist
https://www.readbyqxmd.com/read/28550020/translation-adaptation-and-validation-of-two-versions-of-the-chronic-liver-disease-questionnaire-in-malaysian-patients-for-speakers-of-both-english-and-malay-languages-a-cross-sectional-study
#6
Shasha Khairullah, Sanjiv Mahadeva
OBJECTIVE: We aimed to adapt, translate and validate the Chronic Liver Disease Questionnaire (CLDQ) in Malaysian patients with chronic liver diseases of various aetiologies. SETTING: Tertiary level teaching institution in Malaysia. PARTICIPANTS: The validation process involved 211 adult patients (English language n=101, Malay language n=110) with chronic liver disease. Characteristics of the study subjects were as follows: mean (SD) age was 56 (12...
May 25, 2017: BMJ Open
https://www.readbyqxmd.com/read/28550019/measuring-ability-to-assess-claims-about-treatment-effects-a-latent-trait-analysis-of-items-from-the-claim-evaluation-tools-database-using-rasch-modelling
#7
Astrid Austvoll-Dahlgren, Øystein Guttersrud, Allen Nsangi, Daniel Semakula, Andrew D Oxman
BACKGROUND: The Claim Evaluation Tools database contains multiple-choice items for measuring people's ability to apply the key concepts they need to know to be able to assess treatment claims. We assessed items from the database using Rasch analysis to develop an outcome measure to be used in two randomised trials in Uganda. Rasch analysis is a form of psychometric testing relying on Item Response Theory. It is a dynamic way of developing outcome measures that are valid and reliable. OBJECTIVES: To assess the validity, reliability and responsiveness of 88 items addressing 22 key concepts using Rasch analysis...
May 25, 2017: BMJ Open
https://www.readbyqxmd.com/read/28549946/potential-metabolomic-biomarkers-for-reliable-diagnosis-of-behcet-s-disease-using-gas-chromatography-with-time-of-flight-mass-spectrometry
#8
Joong Kyong Ahn, Jungyeon Kim, Jiwon Hwang, Juhwan Song, Kyoung Heon Kim, Hoon-Suk Cha
OBJECTIVES: Although many diagnostic criteria of Behcet's disease (BD) have been developed and revised by experts, diagnosing BD is still complicated and challenging. No metabolomic studies on serum have been attempted to improve the diagnosis and to identify potential biomarkers of BD. The purposes of this study were to investigate distinctive metabolic changes in serum samples of BD patients and to identify metabolic candidate biomarkers for reliable diagnosis of BD using the metabolomics platform...
May 23, 2017: Joint, Bone, Spine: Revue du Rhumatisme
https://www.readbyqxmd.com/read/28549614/validation-and-comparison-of-four-models-to-calculate-pretest-probability-of-obstructive-coronary-artery-disease-in-a-chinese-population-a-coronary-computed-tomographic-angiography-study
#9
Jia Zhou, Yujie Liu, Lingyu Huang, Yahang Tan, Xingchen Li, Hong Zhang, Yanhe Ma, Ying Zhang
OBJECTIVE: We sought to compare the performance of the updated Diamond-Forrester method (UDFM), Duke clinical score (DCS), Genders clinical model (GCM) and Genders extended model (GEM) in a Chinese population referred to coronary computed tomography angiography (coronary CTA). BACKGROUND: The reliability of existing models to calculate the pretest proability (PTP) of obstructive coronary artery disease (CAD) have not been fully investigated, especially in a Chinese population...
May 11, 2017: Journal of Cardiovascular Computed Tomography
https://www.readbyqxmd.com/read/28549535/relationships-of-measured-iohexol-gfr-and-estimated-gfr-with-ckd-related-biomarkers-in-children-and-adolescents
#10
Derek K Ng, George J Schwartz, Bradley A Warady, Susan L Furth, Alvaro Muñoz
BACKGROUND: 2 valid and reliable estimated glomerular filtration rate (GFR) equations for the pediatric population have been developed from directly measured GFR data in the Chronic Kidney Disease in Children (CKiD) cohort: the full CKiD and bedside CKiD equations. Although adult GFR estimating equations replicate relationships of measured GFR with biomarkers, it is unclear whether similar patterns exist among children and adolescents with chronic kidney disease (CKD). STUDY DESIGN: Prospective cohort study in children and adolescents...
May 24, 2017: American Journal of Kidney Diseases: the Official Journal of the National Kidney Foundation
https://www.readbyqxmd.com/read/28549265/facile-screening-of-potential-xenoestrogens-by-an-estrogen-receptor-based-reusable-optical-biosensor
#11
Lanhua Liu, Xiaohong Zhou, Yun Lu, Didi Shan, Bi Xu, Miao He, Hanchang Shi, Yi Qian
The apparent increase in hormone-induced cancers and disorders of the reproductive tract has led to a growing demand for new technologies capable of screening xenoestrogens. We reported an estrogen receptor (ER)-based reusable fiber biosensor for facile screening estrogenic compounds in environment. The bioassay is based on the competition of xenoestrogens with 17β-estradiol (E2) for binding to the recombinant receptor of human estrogen receptor α (hERα) protein, leaving E2 free to bind to fluorophore-labeled anti-E2 monoclonal antibody...
May 18, 2017: Biosensors & Bioelectronics
https://www.readbyqxmd.com/read/28549241/establishing-the-brief-assessment-of-cognition-short-form
#12
Max Lam, Mingyuan Wang, Wanping Huang, Goi Khia Eng, Attilio Rapisarda, Michael Kraus, Sim Kang, R S E Keefe, Jimmy Lee
The study aims to identify and validate a parsimonious subset of tests in the commonly used Brief Assessment of Cognition in Schizophrenia (BACS) that allows the evaluation of global cognitive ability. Several permutations of subtests from the BACS were examined to identify the best subset of tests to compose the short form measure. The Brief Assessment of Cognition-Short Form (BAC-SF) was evaluated for convergent validity in healthy and psychiatric samples (N = 3718). Verbal Memory, Digit Sequencing, and Symbol Coding subtests were found to best summarize the variance of composite scores in both Asian and US Norming samples (r = 0...
May 17, 2017: Journal of Psychiatric Research
https://www.readbyqxmd.com/read/28549160/the-diabetes-strengths-and-resilience-measure-for-adolescents-with-type-1-diabetes-dstar-teen-validation-of-a-new-brief-self-report-measure
#13
Marisa E Hilliard, Esti Iturralde, Jill Weissberg-Benchell, Korey K Hood
 Despite the challenges of managing type 1 diabetes, many adolescents achieve optimal outcomes. A validated measure of diabetes-specific strengths is needed to measure adaptive behaviors and attitudes associated with overcoming challenges and achieving "resilient" outcomes.  Baseline data from 260 adolescents (age 14-18 years, M  = 15.7 ± 1.1, 60% female, 33% Non-Caucasian, M A1c = 9.1 ± 1.9%) and caregivers in a behavioral intervention trial were analyzed to evaluate psychometric properties of the 12-item self-report Diabetes Strengths and Resilience measure for adolescents (DSTAR-Teen)...
May 26, 2017: Journal of Pediatric Psychology
https://www.readbyqxmd.com/read/28549051/pressure-injuries-in-inpatient-care-facilities-in-the-czech-republic-analysis-of-a-national-electronic-database
#14
Andrea Pokorná, Klára Benešová, Jiří Jarkovský, Jan Mužík, Dimitri Beeckman
PURPOSE: The purpose of this study was to analyze pressure injury (PI) occurrence upon admission and at any time during the hospital course inpatients care facilities in the Czech Republic. Secondary aims were to evaluate demographic and clinical data of patients with PI and the impact of a PI on length of stay (LOS) in the hospital. DESIGN: Retrospective, cross-sectional analysis. SETTING AND SUBJECTS: The sample comprised data of hospitalized patients entered into the National Register of Hospitalized Patients (NRHOSP) database of the Czech Republic between 2007 and 2014 with a diagnosis L89 (pressure ulcer of unspecified site based on the International Classification of Diseases, Tenth Revision, ICD-10)...
May 25, 2017: Journal of Wound, Ostomy, and Continence Nursing
https://www.readbyqxmd.com/read/28548922/development-of-ergonomics-audits-for-bagging-haul-truck-and-maintenance-and-repair-operations-in-mining
#15
Patrick G Dempsey, Jonisha Pollard, William L Porter, Alan Mayton, John R Heberger, Sean Gallagher, Leanna Reardon, Colin G Drury
The development and testing of ergonomics and safety audits for small and bulk bag filling, haul truck, and maintenance and repair operations in coal preparation and mineral processing plants found at surface mine sites is described. The content for the audits was derived from diverse sources of information on ergonomics and safety deficiencies including: analysis of injury, illness, and fatality data and reports; task analysis; empirical laboratory studies of particular tasks; field studies and observations at mine sites; and maintenance records...
May 26, 2017: Ergonomics
https://www.readbyqxmd.com/read/28548919/a-novel-method-for-quanitifying-comfort-in-child-passengers-demonstrates-an-association-between-child-restraint-comfort-and-errors-in-use-of-booster-seats
#16
Cameron K Fong, Lynne E Bilston, Gunther Paul, Julie Brown
OBJECTIVE: Misuse of child restraint systems is a widespread and long-standing problem impacting risk of injury and death in car crashes. Discomfort has been suggested as a causative factor for misuse, particularly in errors introduced by children while they use the restraints. However, the relationship between comfort and errors in use has never been studied. In this study we examine the reliability and sensitivity of a newly developed observational method for assessing comfort in children in vehicles...
May 29, 2017: Traffic Injury Prevention
https://www.readbyqxmd.com/read/28548907/evaluation-of-thermal-optical-analysis-method-of-elemental-carbon-for-marine-fuel-exhaust
#17
Maija K Lappi, Jyrki P Ristimäki
The awareness of black carbon (BC) as the second largest anthropogenic contributor in global warming and an ice melting enhancer has increased. Due to prospected increase in shipping especially in the Arctic reliability of BC emissions and their invented amounts from ships is gaining more attention. The International Maritime Organisation (IMO) is actively working towards estimation of quantities and effects of BC especially in the Arctic. IMO has launched work towards constituting a definition for BC and agreeing appropriate methods for its determination from shipping emission sources...
May 26, 2017: Journal of the Air & Waste Management Association
https://www.readbyqxmd.com/read/28548710/measurement-of-glycine-in-healthy-and-tumorous-brain-by-triple-refocusing-mrs-at-3%C3%A2-t-in-vivo
#18
Vivek Tiwari, Zhongxu An, Sandeep K Ganji, Jeannie Baxter, Toral R Patel, Edward Pan, Bruce E Mickey, Elizabeth A Maher, Marco C Pinho, Changho Choi
Glycine (Gly) has been implicated in several neurological disorders, including malignant brain tumors. The precise measurement of Gly is challenging largely as a result of the spectral overlap with myo-inositol (mI). We report a new triple-refocusing sequence for the reliable co-detection of Gly and mI at 3 T and for the evaluation of Gly in healthy and tumorous brain. The sequence parameters were optimized with density-matrix simulations and phantom validation. With a total TE of 134 ms, the sequence gave complete suppression of the mI signal between 3...
May 26, 2017: NMR in Biomedicine
https://www.readbyqxmd.com/read/28548557/further-examination-of-embedded-performance-validity-indicators-for-the-conners-continuous-performance-test-and-brief-test-of-attention-in-a-large-outpatient-clinical-sample
#19
Michael J Sharland, Stephen C Waring, Brian P Johnson, Allise M Taran, Travis A Rusin, Andrew M Pattock, Jeanette A Palcher
OBJECTIVE: Assessing test performance validity is a standard clinical practice and although studies have examined the utility of cognitive/memory measures, few have examined attention measures as indicators of performance validity beyond the Reliable Digit Span. The current study further investigates the classification probability of embedded Performance Validity Tests (PVTs) within the Brief Test of Attention (BTA) and the Conners' Continuous Performance Test (CPT-II), in a large clinical sample...
May 26, 2017: Clinical Neuropsychologist
https://www.readbyqxmd.com/read/28548541/structure-reliability-measurement-stability-and-construct-validity-of-the-polish-version-of-the-revised-child-anxiety-and-depression-scale
#20
Ilona Skoczeń, Radosław Rogoza, Marta Rogoza, Chad Ebesutani, Bruce Chorpita
The Revised Child Anxiety and Depression Scale (RCADS) is a self-report questionnaire that aims to assess symptoms of anxiety and depressive disorders in children. Two studies were conducted to evaluate the psychometric properties of the Polish version of the RCADS. Study 1 was conducted to analyze the structural validity and reliability of the RCADS scores and Study 2 assessed the longitudinal measurement of stability over time. Data were collected from a community sample of 501 children and adolescents aged 8 to 14 years in Poland...
May 1, 2017: Assessment
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