Igor Longobardi, Danilo Marcelo Leite do Prado, Danieli Castro Oliveira de Andrade, Karla Fabiana Goessler, Gersiel Nascimento de Oliveira Júnior, Rafael de Almeida Azevedo, Alice Erwig Leitão, Jhonnatan Vasconcelos Pereira Santos, Ana Lúcia de Sá Pinto, Bruno Gualano, Hamilton Roschel
Post-acute Sequelae of SARS-CoV-2 infection (PASC) often leads to exertional intolerance and reduced exercise capacity, particularly in individuals previously admitted to an intensive care unit (ICU). However, the impact of invasive mechanical ventilation (IMV) on PASC-associated cardiorespiratory abnormalities during exercise remains poorly understood. This single-center, cross-sectional study aimed to gather knowledge on this topic. Fifty-two patients with PASC recruited ~6 months after ICU discharge were clustered based on their need for IMV (PASC+IMV, n=27) or non-invasive support therapy (PASC+NIS, n=25)...
February 9, 2024: American Journal of Physiology. Heart and Circulatory Physiology