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Hospital Mortality, Myocardial infarction

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https://www.readbyqxmd.com/read/29931649/one-year-efficacy-and-safety-of-routine-prasugrel-in-patients-with-acute-coronary-syndromes-treated-with-percutaneous-coronary-intervention-results-of-the-prospective-rijnmond-collective-cardiology-research-study
#1
T Yetgin, E Boersma, P C Smits, A G de Vries, E Huijskens, F Zijlstra, M M J M van der Linden, R J M van Geuns
OBJECTIVE: To investigate 1‑year outcomes with routine prasugrel treatment after acute coronary syndrome (ACS) in a large-scale registry. METHODS: The Rijnmond Collective Cardiology Research registry is a prospective, observational study that enrolled 4,258 consecutive ACS patients treated with percutaneous coronary intervention (PCI) with 1‑year follow-up. Patients received prasugrel as first-choice antiplatelet agent, except for increased bleeding risk patients in which clopidogrel was recommended...
June 21, 2018: Netherlands Heart Journal
https://www.readbyqxmd.com/read/29929933/hospital-mortality-and-thirty-day-readmission-among-patients-with-non-acute-myocardial-infarction-related-cardiogenic-shock
#2
Mahek Shah, Brijesh Patel, Byomesh Tripathi, Manyoo Agarwal, Soumya Patnaik, Pradhum Ram, Shantanu Patil, Jooyoung Shin, Ulrich P Jorde
BACKGROUND: Cardiogenic shock (CS) in absence of acute myocardial infarction (AMI) has significant morbidity and mortality. This population of patients has been excluded from prior major randomized trials and observational studies. METHODS: We included patients with CS in absence of AMI from the 2013-14 HCUP's National Readmission Database. 30-day readmissions were studied and etiology for readmission was identified by using ICD-9CM codes in primary diagnosis field...
June 10, 2018: International Journal of Cardiology
https://www.readbyqxmd.com/read/29929759/incidence-and-trends-of-cardiac-complications-in-major-abdominal-surgery
#3
Yas Sanaiha, Yen-Yi Juo, Esteban Aguayo, Young-Ji Seo, Vishal Dobaria, Boback Ziaeian, Peyman Benharash
INTRODUCTION: Cardiovascular complications are the leading cause of death after noncardiac surgery. Major abdominal operations represent the largest category of procedures considered to have an increased risk of cardiovascular complications. The current aim was to examine trends in the incidence of mortality, perioperative myocardial infarction, and cardiac arrest to determine the presence of potential volume-outcome relationships. METHODS: We performed a retrospective analysis of the Nationwide Inpatient Sample for patients undergoing elective, open abdominal esophagectomy, gastrectomy, pancreatectomy, nephrectomy, hepatectomy, splenectomy, and colectomy (major abdominal surgery) during 2008-2014...
June 18, 2018: Surgery
https://www.readbyqxmd.com/read/29929641/outcomes-following-urgent-emergent-transcatheter-aortic-valve-replacement-insights-from-the-sts-acc-tvt-registry
#4
Dhaval Kolte, Sahil Khera, Sreekanth Vemulapalli, Dadi Dai, Stephan Heo, Andrew M Goldsweig, Herbert D Aronow, Sammy Elmariah, Ignacio Inglessis, Igor F Palacios, Vinod H Thourani, Barry L Sharaf, Paul C Gordon, J Dawn Abbott
OBJECTIVES: The authors sought to examine outcomes and identify independent predictors of mortality among patients undergoing urgent/emergent transcatheter aortic valve replacement (TAVR). BACKGROUND: Data on urgent/emergent TAVR as a rescue therapy for decompensated severe aortic stenosis (AS) are limited. METHODS: The Society of Thoracic Surgeons and the American College of Cardiology Transcatheter Valve Therapy (STS/ACC TVT) Registry linked with Centers for Medicare & Medicaid Services claims was used to identify patients who underwent urgent/emergent versus elective TAVR between November 2011 and June 2016...
June 25, 2018: JACC. Cardiovascular Interventions
https://www.readbyqxmd.com/read/29928687/nationwide-real-world-database-of-20-462-patients-enrolled-in-the-japanese-acute-myocardial-infarction-registry-jamir-impact-of-emergency-coronary-intervention-in-a-super-aging-population
#5
Sunao Kojima, Kensaku Nishihira, Misa Takegami, Yoko M Nakao, Satoshi Honda, Jun Takahashi, Morimasa Takayama, Hiroaki Shimokawa, Tetsuya Sumiyoshi, Hisao Ogawa, Kazuo Kimura, Satoshi Yasuda
Background: Cardiovascular diseases, including acute myocardial infarction (AMI), are leading causes of death among the Japanese, who have the longest life expectancy in the world. Over the past 50 years in Japan, the percentage of elderly individuals has increased 4-fold, from 5.7% in 1960 to 23.1% in 2010. To explore medical practices and emergency care for AMI in this aging society, the Japan Acute Myocardial Infarction Registry (JAMIR) was established as a nationwide real-world database...
September 2018: IJC Heart & Vasculature
https://www.readbyqxmd.com/read/29927947/regional-to-tertiary-inter-hospital-transfer-versus-in-house-percutaneous-coronary-intervention-in-acute-coronary-syndrome
#6
Delara Javat, Clare Heal, Jennifer Banks, Stefan Buchholz, Zhihua Zhang
RATIONALE: To address the inaccessibility of interventional cardiac services in North Queensland a new cardiac catheterisation laboratory (CCL) was established in Mackay Base Hospital (MBH) in February 2014. OBJECTIVE: To determine whether the provision of in-house angiography and/or percutaneous coronary intervention (PCI) 1) minimises treatment delays 2) further reduces the risk of mortality, recurrent myocardial infarction (MI) and recurrent ischaemia 3) improves patient satisfaction and 4) minimises cost expenditure compared with inter-hospital transfer for patients with acute coronary syndrome (ACS)...
2018: PloS One
https://www.readbyqxmd.com/read/29924379/survival-benefit-from-recent-changes-in-management-of-men-and-women-with-st-elevation-myocardial-infarction-treated-with-percutaneous-coronary-interventions
#7
Łukasz Zandecki, Marcin Sadowski, Marianna Janion, Jacek Kurzawski, Marek Gierlotka, Lech Poloński, Mariusz Gąsior
BACKGROUND: Nowadays, the majority of patients with myocardial infarction with ST-segment elevation (STEMI) are treated with primary percutaneous coronary interventions (pPCI). In recent years, there have been ongoing improvements in PCI techniques, devices and concomitant pharmacotherapy. However, reports on further mortality reduction among PCI-treated STEMI patients remain inconclusive. The aim of this study was to compare changes in management and mortality in PCI-treated STEMI patients between 2005 and 2011 in a real-life setting...
June 20, 2018: Cardiology Journal
https://www.readbyqxmd.com/read/29924033/is-the-mean-platelet-volume-a-predictive-marker-of-a-high-in-hospital-mortality-of-acute-cardiorenal-syndrome-patients-receiving-continuous-renal-replacement-therapy
#8
Junhui Li, Xiaohua Sheng, Dongsheng Cheng, Feng Wang, Guihua Jian, Yongguang Li, Tao Xu, Xiaoxia Wang, Ying Fan, Niansong Wang
A high mean platelet volume (MPV) level has been demonstrated to predict poor clinical outcomes in patients with cardiovascular disease. However, the relationship between MPV and mortality in patients with acute cardiorenal syndrome (ACRS) is unknown. Therefore, we investigated the predictive value of MPV for in-hospital mortality of patients with ACRS who received continuous renal replacement therapy (CRRT) in this study.We retrospectively analyzed the demographics, etiology, severity of illness, prognosis, and risk factors of ACRS patients who underwent CRRT in our hospital from January 2009 to December 2014...
June 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29922732/prognostic-value-of-plasma-st2-in-patients-with-non-st-segment-elevation-acute-coronary-syndrome
#9
Çağrı Kokkoz, Adnan Bilge, Mehmet Irik, Halil I Dayangaç, Mustafa Hayran, Funda Karbek Akarca, Nimet Bilal Erdem, Musa Çavuş
Objective: The aim of this study is to detect plasma ST2 levels in patients who were admitted to emergency department with chest pain and diagnosed with non st segment elevation myocardial infarction (NSTEMI) and to research the relationship between 28-day mortality and ST2 levels. Methods: The present study was conducted at Emergency Department of Celal Bayar University Hafsa Sultan Hospital between September 2015 and January 2016 as a prospective, single-center, cross-sectional study...
June 2018: Turkish Journal of Emergency Medicine
https://www.readbyqxmd.com/read/29922097/acute-myocardial-infarction-in-young-women-current-perspectives
#10
REVIEW
Jaya Chandrasekhar, Amrita Gill, Roxana Mehran
Acute myocardial infarction (AMI) is the leading cause of death in women worldwide. Every year, in the USA alone, more than 30,000 young women <55 years of age are hospitalized with AMI. In recent decades, the incidence of AMI is increasing in younger women in the context of increasing metabolic syndrome, diabetes mellitus, and non-traditional risk factors such as stress, anxiety, and depression. Although women are classically considered to present with atypical chest pain, several observational data confirm that men and women experience similar rates of chest pain, with some differences in intensity, duration, radiation, and the choice of descriptors...
2018: International Journal of Women's Health
https://www.readbyqxmd.com/read/29920523/telomere-length-and-mortality-in-the-ludwigshafen-risk-and-cardiovascular-health-study
#11
Irene Pusceddu, Marcus Kleber, Graciela Delgado, Wolfgang Herrmann, Winfried März, Markus Herrmann
INTRODUCTION: Short telomeres have been associated with adverse lifestyle factors, cardiovascular risk factors and age-related diseases, including cardiovascular disease (CVD), myocardial infarction, atherosclerosis, hypertension, diabetes, and also with mortality. However, previous studies report conflicting results. OBJECTIVES: The aim of the present study has been to investigate the involvement of telomere length in all-cause and CVD mortality in subjects hospitalized for diagnostic coronary angiography of the Ludwigshafen Risk and Cardiovascular Health (LURIC) study...
2018: PloS One
https://www.readbyqxmd.com/read/29917260/does-obesity-affect-the-outcomes-in-takotsubo-cardiomyopathy-analysis-of-the-nationwide-inpatient-sample-database-2010-2014
#12
Rupak Desai, Sandeep Singh, Maryam Baikpour, Hemant Goyal, Abhijeet Dhoble, Abhishek Deshmukh, Gautam Kumar, Rajesh Sachdeva
BACKGROUND: It is well known that obesity can lead to increased oxidative stress, which is one of the proposed mechanisms in the etiopathogenesis of Takotsubo Cardiomyopathy (TCM). However, it is unknown if the presence of obesity affects the outcomes in patients with TCM. METHODS: We queried the National Inpatient Sample database from 2010-2014 to identify adult patients who admitted with a principal diagnosis of TCM with and without obesity. We compared the categorical and continuous variables by Pearson's chi-square and Student's t-test respectively in propensity-score matched cohorts...
June 19, 2018: Clinical Cardiology
https://www.readbyqxmd.com/read/29910059/bivalirudin-versus-heparin-with-primary-percutaneous-coronary-intervention
#13
Dimitrios Venetsanos, Sofia Sederholm Lawesson, Stefan James, Sasha Koul, David Erlinge, Eva Swahn, Joakim Alfredsson
BACKGROUND: Optimal adjunctive therapy in ST-segment elevation myocardial infarction (STEMI) patients treated with primary PCI (PPCI) remains a matter of debate. Our aim was to compare the efficacy and safety of bivalirudin to unfractionated heparin (UFH), with or without glycoprotein IIb/IIIa inhibitors (GPI) in a large real-world population, using data from the Swedish national registry, SWEDEHEART. METHOD: From 2008 to 2014 we identified 23,800 STEMI patients presenting within 12 hours from symptom onset treated with PPCI and UFH ± GPI or bivalirudin±GPI...
July 2018: American Heart Journal
https://www.readbyqxmd.com/read/29910048/discharge-timing-and-outcomes-after-uncomplicated-non-st-segment-elevation-acute-myocardial-infarction
#14
Jennifer A Rymer, Michael W Tempelhof, Robert M Clare, Karen S Pieper, Christopher B Granger, Frans Van de Werf, David J Moliterno, Robert A Harrington, Harvey D White, Paul W Armstrong, Renato D Lopes, Kenneth W Mahaffey, L Kristin Newby
BACKGROUND: Length of stay after non-ST-segment elevation myocardial infarction (NSTEMI) continues to decrease, but information to guide duration of hospitalization is limited. METHODS: We used landmark analyses, in which the landmark defined potential days of discharge, to estimate complication rates on the first day the patient would have been out of the hospital, and estimated associations between timing of discharge and 30-day and 1-year event-free survival after discharge among NSTEMI patients...
July 2018: American Heart Journal
https://www.readbyqxmd.com/read/29909948/revascularization-strategies-in-cardiogenic-shock-complicating-acute-myocardial-infarction-a-systematic-review-and-meta-analysis
#15
Hammad Rahman, Safi U Khan, Ahmad N Lone, Edo Kaluski
BACKGROUND: The optimal revascularization strategy in patients with multi-vessel disease (MVD) presenting with acute myocardial infarction (AMI) and cardiogenic shock (CS) remains unclear. OBJECTIVE: To investigate the comparative differences between culprit-only revascularization (COR) versus instant multi-vessel revascularization (IMVR) in AMI and CS. METHODS: 13 studies were selected using MEDLINE, EMBASE and the CENTRAL (Inception - 31 November2017)...
June 9, 2018: Cardiovascular Revascularization Medicine: Including Molecular Interventions
https://www.readbyqxmd.com/read/29909156/high-dose-influenza-vaccine-to-reduce-clinical-outcomes-in-high-risk-cardiovascular-patients-rationale-and-design-of-the-invested-trial
#16
Orly Vardeny, Jacob A Udell, Jacob Joseph, Michael E Farkouh, Adrian F Hernandez, Alison J McGeer, H Keipp Talbot, Deepak L Bhatt, Christopher P Cannon, Shaun G Goodman, Inder Anand, David L DeMets, Jon Temte, Janet Wittes, Kristin Nichol, Clyde W Yancy, J Michael Gaziano, Lawton S Cooper, KyungMann Kim, Scott D Solomon
BACKGROUND: Influenza leads to significant cardiopulmonary morbidity and mortality-particularly in patients with cardiovascular disease-that may be prevented with a standard influenza vaccine. However, patients with cardiovascular conditions have a reduced immune response to influenza vaccine, potentially resulting in reduced effectiveness for preventing clinical events. High-dose vaccine augments immune response in cardiac patients, suggesting that a high-dose influenza vaccination strategy may further reduce morbidity and mortality...
May 23, 2018: American Heart Journal
https://www.readbyqxmd.com/read/29906667/the-high-cost-of-critical-care-unit-over-utilization-for-patients-with-nste-acs
#17
Sean van Diepen, Dat T Tran, Justin A Ezekowitz, David A Zygun, Jason N Katz, Renato D Lopes, L Kristin Newby, Finlay A McAlister, Padma Kaul
BACKGROUND: There is substantial variability among hospitals in critical care unit (CCU) utilization for patients admitted with non-ST-Segment Elevation Acute Coronary Syndromes (NSTE ACS). We estimated the potential cost saving if all hospitals adopted low CCU utilization practices for patients with NSTE ACS. METHODS: National hospital claims data were used to identify all patients with a primary diagnosis of NSTE ACS initially admitted to an acute care hospital between 2007 and 2013...
May 19, 2018: American Heart Journal
https://www.readbyqxmd.com/read/29901624/predictors-and-prognosis-for-incident-in-hospital-heart-failure-in-patients-with-preserved-ejection-fraction-after-first-acute-myocardial-infarction-an-observational-study
#18
Mingzhu Xu, Lihua Yan, Jialiang Xu, Xiangjun Yang, Tingbo Jiang
Patients with acute myocardial infarction (AMI) complicated by heart failure with preserved ejection fraction (HFpEF) are likely to have more adverse cardiovascular events and higher mortality. The purpose of this study was to examine the predictors and outcomes in AMI patients complicated by HFpEF.We examined the demographics, clinical data, and clinical outcomes in 405 consecutive subjects who firstly presented with AMI after undergoing emergency percutaneous coronary intervention from January 2013 to June 2016...
June 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29900874/dabigatran-in-patients-with-myocardial-injury-after-non-cardiac-surgery-manage-an-international-randomised-placebo-controlled-trial
#19
P J Devereaux, Emmanuelle Duceppe, Gordon Guyatt, Vikas Tandon, Reitze Rodseth, Bruce M Biccard, Denis Xavier, Wojciech Szczeklik, Christian S Meyhoff, Jessica Vincent, Maria Grazia Franzosi, Sadeesh K Srinathan, Jason Erb, Patrick Magloire, John Neary, Mangala Rao, Prashant V Rahate, Navneet K Chaudhry, Bongani Mayosi, Miriam de Nadal, Pilar Paniagua Iglesias, Otavio Berwanger, Juan Carlos Villar, Fernando Botto, John W Eikelboom, Daniel I Sessler, Clive Kearon, Shirley Pettit, Mukul Sharma, Stuart J Connolly, Shrikant I Bangdiwala, Purnima Rao-Melacini, Andreas Hoeft, Salim Yusuf
BACKGROUND: Myocardial injury after non-cardiac surgery (MINS) increases the risk of cardiovascular events and deaths, which anticoagulation therapy could prevent. Dabigatran prevents perioperative venous thromboembolism, but whether this drug can prevent a broader range of vascular complications in patients with MINS is unknown. The MANAGE trial assessed the potential of dabigatran to prevent major vascular complications among such patients. METHODS: In this international, randomised, placebo-controlled trial, we recruited patients from 84 hospitals in 19 countries...
June 9, 2018: Lancet
https://www.readbyqxmd.com/read/29899013/assessment-of-cardiovascular-risk-in-older-patients-with-gout-initiating-febuxostat-versus-allopurinol-a-population-based-cohort-study
#20
MaryAnn Zhang, Daniel H Solomon, Rishi J Desai, Eun Ha Kang, Jun Liu, Tuhina Neogi, Seoyoung C Kim
Background -Hyperuricemia and gout are associated with increased risk of cardiovascular disease (CVD). Xanthine oxidase inhibitors (XOI), allopurinol and febuxostat, are the mainstay of urate lowering treatment for gout and may have different effects on cardiovascular risk in patients with gout. Methods -Using U.S. Medicare claims data (2008-2013), we conducted a cohort study for comparative cardiovascular safety of initiating febuxostat versus allopurinol among gout patients aged ≥65 years. The primary outcome was a composite endpoint of hospitalization for myocardial infarction (MI) or stroke...
June 13, 2018: Circulation
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