keyword
MENU ▼
Read by QxMD icon Read
search

Sapien 3

keyword
https://www.readbyqxmd.com/read/29765111/new-insights-into-apoptosome-structure-and-function
#1
REVIEW
Loretta Dorstyn, Christopher W Akey, Sharad Kumar
The apoptosome is a platform that activates apical procaspases in response to intrinsic cell death signals. Biochemical and structural studies in the past two decades have extended our understanding of apoptosome composition and structure, while illuminating the requirements for initiator procaspase activation. A number of studies have now provided high-resolution structures for apoptosomes from C. elegans (CED-4), D. melanogaster (Dark), and H. sapiens (Apaf-1), which define critical protein interfaces, including intra and interdomain interactions...
May 15, 2018: Cell Death and Differentiation
https://www.readbyqxmd.com/read/29762934/rescue-tavi-for-aortic-regurgitation-after-left-ventricular-assist-device-implantation-following-preoperative-impella%C3%A2-support
#2
Florian E M Herrmann, Petra Wellmann, Vera von Dossow, Steffen Massberg, Christian Hagl, René Schramm, Maximilian Pichlmaier
A patient presented with a decompensated cardiomyopathy requiring invasive hemodynamic support with an Impella® heart pump. Extracorporeal life support (ECLS) became necessary during the further course and the patient was bridged to left ventricular assist device (LVAD) implantation. Postoperatively, the patient did not improve as expected due to new aortic regurgitation (AR) that was most likely caused by the previously placed Impella. A SAPIEN 3 transcatheter aortic valve was implanted as a bail-out strategy; an additional valve-in-valve rescue was required due to paravalvular regurgitation...
September 2017: Journal of Heart Valve Disease
https://www.readbyqxmd.com/read/29753441/a-new-tephrochronology-for-early-diverse-stone-tool-technologies-and-long-distance-raw-material-transport-in-the-middle-to-late-pleistocene-kapthurin-formation-east-africa
#3
Nick Blegen, Brian R Jicha, Sally McBrearty
The Middle to Late Pleistocene (780-10 ka) of East Africa records evidence of significant behavioral change, early fossils of Homo sapiens, and the dispersals of our species across and out of Africa. Studying human evolution in this time period thus requires an extensive and precise chronology relating behavioral evidence from archaeological sequences to aspects of hominin biology and evidence of past environments from fossils and geological sequences. Tephrochronology provides the chronostratigraphic resolution to achieve this through correlation and dating of volcanic ashes...
May 9, 2018: Journal of Human Evolution
https://www.readbyqxmd.com/read/29735900/synthesis-biological-evaluation-and-docking-studies-of-novel-bisquaternary-aldoxime-reactivators-on-acetylcholinesterase-and-butyrylcholinesterase-inhibited-by-paraoxon
#4
Kamil Kuca, Daniel Jun, Lucie Junova, Kamil Musilek, Martina Hrabinova, Jorge Alberto Valle da Silva, Teodorico Castro Ramalho, Marian Valko, Qinghua Wu, Eugenie Nepovimova, Tanos Celmar Costa França
Nerve agents and oxon forms of organophosphorus pesticides act as strong irreversible inhibitors of two cholinesterases in the human body: acetylcholinesterase (AChE; EC 3.1.1.7) and butyrylcholinesterase (BChE; EC 3.1.1.8), and are therefore highly toxic compounds. For the recovery of inhibited AChE, antidotes from the group of pyridinium or bispyridinium aldoxime reactivators (pralidoxime, obidoxime, HI-6) are used in combination with anticholinergics and anticonvulsives. Therapeutic efficacy of reactivators (called “oximes”) depends on their chemical structure and also the type of organophosphorus inhibitor...
May 7, 2018: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://www.readbyqxmd.com/read/29726601/comparison-of-paravalvular-aortic-leak-characteristics-in-the-medtronic-corevalve-versus-edwards-sapien-valve-paravalvular-aortic-leak-characteristics
#5
Olivia N Gilbert, Charles H Choi, Jodie L Franzil, Melissa Caughey, Waqas Qureshi, R Brandon Stacey, Min Pu, Robert J Applegate, Sanjay K Gandhi, David X M Zhao
OBJECTIVES: Temporally quantify and localize paravalvular aortic leak (PVL) after transcatheter aortic valve replacement (TAVR) in the Medtronic CoreValve (MCV) versus the Edwards Sapien Valve (ESV). BACKGROUND: In order to increase the precision of THV selection and PVL intervention, an understanding of PVL characteristics is essential. METHODS: The frequency, severity, and location of post-TAVR PVL were evaluated with transthoracic echocardiography pre-discharge, one month, and one-year post-procedure in 202 patients receiving a MCV (N = 120) or ESV (N = 81)...
May 4, 2018: Catheterization and Cardiovascular Interventions
https://www.readbyqxmd.com/read/29706182/prognostic-impact-of-calcium-score-after-transcatheter-aortic-valve-implantation-performed-with-new-generation-prosthesis
#6
Mariama Akodad, Benoit Lattuca, Audrey Agullo, Jean-Christophe Macia, Thomas Gandet, Grégory Marin, Anaïs Iemmi, Hélène Vernhet, Laurent Schmutz, Nicolas Nagot, Bernard Albat, Guillaume Cayla, Florence Leclercq
Calcium score (CS) is a well-known prognostic factor after transcatheter aortic valve implantation (TAVI) performed with first generation prosthesis but few data are available concerning new generation valves. The aim of this study was to evaluate if CS remains a prognostic factor after Sapien 3 and Evolut R valves implantation. Agatston CS was evaluated on multislice computed tomography before TAVI in 346 patients implanted with Sapien XT (n = 61), CoreValve (n = 57) devices, (group 1, n = 118), and with new generation Sapien 3 (n = 147), Evolut R (n = 81) prosthesis, (group 2, n = 228)...
May 15, 2018: American Journal of Cardiology
https://www.readbyqxmd.com/read/29703437/incidence-predictors-and-impact-of-vascular-complications-after-transfemoral-transcatheter-aortic-valve-implantation-with-the-sapien-3-prosthesis
#7
Floortje van Kesteren, Martijn S van Mourik, Jeroen Vendrik, Esther M A Wiegerinck, José P S Henriques, Karel T Koch, Joanna J Wykrzykowska, Rob J de Winter, Jan J Piek, Krijn P van Lienden, Jim A Reekers, M Marije Vis, R Nils Planken, Jan Baan
Vascular complications (VCs) after transfemoral transcatheter aortic valve implantation (TAVI) have always been reported to occur frequently. Studies addressing VCs have been conducted with older-generation prostheses. We aimed to evaluate the incidence, predictors, and impact of VCs after transfemoral TAVI with the balloon-expandable SAPIEN 3. We report a single-center retrospective analysis of 400 consecutive patients of a prospectively acquired cohort. All patients underwent transfemoral TAVI with SAPIEN 3 between January 2014 and December 2016...
May 15, 2018: American Journal of Cardiology
https://www.readbyqxmd.com/read/29688322/conduction-dynamics-after-transcatheter-aortic-valve-implantation-and-implications-for-permanent-pacemaker-implantation-and-early-discharge-the-conduct-study
#8
Lennart van Gils, Sara Baart, Herbert Kroon, Zouhair Rahhab, Nahid El Faquir, Ramón Rodriguez Olivares, Yaar Aga, Anne-Marie Maugenest, Dominic A Theuns, Eric Boersma, Tamas Szili Torok, Peter P De Jaegere, Nicolas M Van Mieghem
Aims: To correlate dynamics in electrical conduction after transcatheter aortic valve implantation (TAVI) with need for permanent pacemaker implantation (PPM) and assess implications for early discharge. Methods and results: Daily electrocardiograms after TAVI were analysed for rhythm and conduction times and were correlated with PPM. Transcatheter aortic valve implantation was performed in 291 consecutive patients with three contemporary transcatheter heart valve designs: Medtronic CoreValve (n = 111), Edwards Sapien XT (n = 29) and Sapien 3 (n = 72), and Boston Lotus (n = 79)...
April 20, 2018: Europace: European Pacing, Arrhythmias, and Cardiac Electrophysiology
https://www.readbyqxmd.com/read/29688174/matched-comparison-of-next-and-early-generation-balloon-expandable-transcatheter-heart-valve-implantations-in-failed-surgical-aortic-bioprostheses
#9
Moritz Seiffert, Hendrik Treede, Joachim Schofer, Axel Linke, Jochen Woehrle, Hardy Baumbach, Julinda Mehilli, Vinayak Bapat, Matheus Simonato, Thomas Walther, Mathias Kullmer, Peter Boekstegers, Stephan Ensminger, Thomas Kurz, Hélène Eltchaninoff, Ardawan Rastan, Nicolas Werner, Arend de Weger, Christian Frerker, Bernward Lauer, Olivier Muller, Brian Whisenant, Arun Thukkani, Giora Weisz, Danny Dvir
AIMS: Transcatheter valve-in-valve implantation (VinV) is established for the treatment of degenerated surgical bioprostheses in patients at high operative risk. Our aim was to report on the first large assessment of VinV with next generation balloon-expandable transcatheter heart valves. METHODS AND RESULTS: 514 patients after SAPIEN XT or SAPIEN 3 VinV were analyzed using an inverse probability of treatment weighting. Standardized clinical and hemodynamic outcomes were compared and core laboratory evaluation of implantation depth was performed...
April 24, 2018: EuroIntervention
https://www.readbyqxmd.com/read/29673509/incidence-predictors-and-clinical-impact-of-prosthesis-patient-mismatch-following-transcatheter-aortic-valve-replacement-in-asian-patients-the-ocean-tavi-registry
#10
Masaki Miyasaka, Norio Tada, Masataka Taguri, Shigeaki Kato, Yusuke Enta, Tatsushi Otomo, Masaki Hata, Yusuke Watanabe, Toru Naganuma, Motoharu Araki, Futoshi Yamanaka, Shinichi Shirai, Hiroshi Ueno, Kazuki Mizutani, Minoru Tabata, Akihiro Higashimori, Kensuke Takagi, Masanori Yamamoto, Kentaro Hayashida
OBJECTIVES: The authors sought to investigate the prevalence, risk factors, and mid-term mortality in Asian patients with prosthesis-patient mismatch (PPM) after transcatheter aortic valve replacement (TAVR). BACKGROUND: Little information is available on PPM after TAVR in Asian patients. METHODS: The authors included 1,558 patients enrolled in the OCEAN-TAVI (Optimized transCathEter vAlvular iNtervention) Japanese multicenter registry from October 2013 to July 2016 after excluding patients who died following TAVR before discharge...
April 23, 2018: JACC. Cardiovascular Interventions
https://www.readbyqxmd.com/read/29627180/transatrial-implantation-of-a-transcatheter-heart-valve-for-severe-mitral-annular-calcification
#11
Fabien Praz, Omar K Khalique, Raymond Lee, Ramesh Veeragandham, Hyde Russell, Mayra Guerrero, Ashequl M Islam, David W Deaton, Tsuyoshi Kaneko, Susheel K Kodali, Martin B Leon, Vinayak Bapat, Hiroo Takayama, Michael A Borger, Isaac George
OBJECTIVE: To assess the outcomes of transatrial implantation of a transcatheter heart valve (THV) for the treatment of mitral valve disease with severe mitral annular calcification (MAC). METHODS: Implantation of a balloon-expandable THV was performed on cardiopulmonary bypass via left atrial exposure in patients considered at risk for left ventricular outflow tract obstruction. The anterior mitral valve leaflet was systematically resected and pledgeted sutures were placed to enhance stability and reduce paravalvular leak...
March 12, 2018: Journal of Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/29623280/neo-left-main-channel-creation-using-double-stenting-alongside-a-sapien-3-aortic-valve-bioprosthesis-for-left-main-coronary-obstruction-following-valve-in-valve-transcatheter-aortic-valve-replacement-a-case-report-with-review-of-literature
#12
Apurva D Patel, Thomas Haldis, Kais Al Balbissi, Timir Paul
Transcatheter aortic valve replacement in the setting of failed surgical bioprosthesis (valve-in-valve) is a valuable option for patients with bioprosthetic aortic stenosis or regurgitation who are deemed high risk for repeat open heart surgery. Although the procedure is successful with proper preprocedural assessment, instances of left main (LM) coronary artery ostium obstruction have been documented. We present a case of LM coronary obstruction in the immediate postoperative period following implantation of a 20-mm Edwards Sapien 3 valve inside the degenerated 21-mm Mitroflow bioprosthesis stenosis, which was treated with double stenting alongside the Edwards Sapien 3 valve creating a channel ("neo left main") that extended from mid-LM to the upper margin of the Edwards Sapien 3 valve...
January 2018: Journal of Investigative Medicine High Impact Case Reports
https://www.readbyqxmd.com/read/29622987/outcome-of-transcatheter-aortic-valve-implantation-in-high-risk-patients-with-severe-aortic-stenosis
#13
Hamdy Soliman, Khlid Alrabaat, Tarek Aboalaazm, Shaimaa Mostafa, Asaad Samy
Aim: To assess outcome of TAVI in high risk patients with severe symptomatic aortic stenosis. Patients and methods: 40 patients with symptomatic severe aortic stenosis and high risk underwent TAVI with implantation of either Sapien XT valve or Core Valve and followed for 6 months. Device success, cardiovascular mortality, myocardial infarction, stroke, life-threatening bleeding and vascular complications were defined according to Valve Academic Research Consortium definitions...
December 2017: The Egyptian heart journal: (EHJ): official bulletin of the Egyptian Society of Cardiology
https://www.readbyqxmd.com/read/29617804/feasibility-of-transcatheter-aortic-valve-implantation-in-patients-with-coronary-heights-%C3%A2-7-mm-insights-from-the-transcatheter-aortic-valve-implantation-karlsruhe-tavik-registry
#14
Lars O Conzelmann, Alexander Würth, Gerhard Schymik, Holger Schröfel, Tonic Anusic, Stefanie Temme, Panagiotis Tzamalis, Jan Gerhardus, Chirojit Mukherjee, Bernd-Dieter Gonska, Claus Schmitt, Uwe Mehlhorn
OBJECTIVES: Transcatheter aortic valve implantation (TAVI) in patients with low coronary heights is generally denied but is not impossible. Information about these high-risk procedures is sparse. METHODS: Since May 2008, data of more than 3000 patients who had TAVI were prospectively collected in the institutional TAVI Karlsruhe registry. Characteristics, peri- and postoperative outcome of patients with low coronary heights of ≤7 mm were analysed according to the Valve Academic Research Consortium-2...
April 2, 2018: European Journal of Cardio-thoracic Surgery
https://www.readbyqxmd.com/read/29610447/very-late-migration-of-balloon-expandable-transcatheter-aortic-valve
#15
Ankur Kalra, Eleonora Avenatti, Ponraj Chinnadurai, Michael J Reardon, Neal S Kleiman, Stephen H Little, Colin M Barker
Color-flow Doppler transesophageal echocardiography during valve-in-valve TAVR illustrates the placement of a 23 mm Edwards Sapien 3 valve carefully positioned within a displaced 23 mm Edwards Sapien XT valve.
April 2018: Journal of Invasive Cardiology
https://www.readbyqxmd.com/read/29610444/hemodynamic-effects-of-valve-asymmetry-in-sapien-3-transcatheter-aortic-valves
#16
Daniel R Mangels, Mary Siki, Rohan Menon, Joseph Bavaria, Saif Anwaruddin, Jay Giri, Nimesh Desai, Wilson Y Szeto, Prashanth Vallabhajosyula, Howard C Herrmann
BACKGROUND: Eccentric valve deployment after transcatheter aortic valve replacement (TAVR) has been associated with abnormal leaflet shear stresses that may accelerate structural valve deterioration (SVD). This phenomenon has not been studied in patients receiving Sapien 3 prostheses (Edwards Lifesciences). METHODS: A retrospective cohort analysis of 100 patients who received Sapien 3 valves between 2013 and 2015 at a single institution was performed. Axial fluoroscopic images from the co-planar view were used to assess TAVR asymmetry, which was defined as a ratio of left-to-right valve heights ≤0...
April 2018: Journal of Invasive Cardiology
https://www.readbyqxmd.com/read/29608725/homo-sapiens-specific-binding-site-variants-within-brain-exclusive-enhancers-are-subject-to-accelerated-divergence-across-human-population
#17
Rabail Zehra, Amir Ali Abbasi
Empirical assessments of human accelerated noncoding DNA frgaments have delineated presence of many cis-regulatory elements. Enhancers make up an important category of such accelerated cis-regulatory elements that efficiently control the spatiotemporal expression of many developmental genes. Establishing plausible reasons for accelerated enhancer sequence divergence in Homo sapiens has been termed significant in various previously published studies. This acceleration by including closely related primates and archaic human data has the potential to open up evolutionary avenues for deducing present-day brain structure...
March 1, 2018: Genome Biology and Evolution
https://www.readbyqxmd.com/read/29589310/rt-qpcr-for-fecal-mature-microrna-quantification-and-validation
#18
Farid E Ahmed, Nancy C Ahmed, Mostafa M Gouda, Paul W Vos, Chris Bonnerup
By routinely and systematically being able to perform quantitative stem-loop reverse transcriptase (RT) followed by TaqMan® minor-groove binding (MGB) probe, real-time quantitative PCR analysis on exfoliated enriched colonocytes in stool, using human (Homo sapiens, hsa) micro(mi)RNAs to monitor changes of their expression at various stages of colorectal (CRC) progression, this method allows for the reliable and quantitative diagnostic screening of colon cancer (CC). Although the expression of some miRNA genes tested in tissue shows less variability in normal or cancerous patients than in stool, the noninvasive stool by itself is well suited for CC screening...
2018: Methods in Molecular Biology
https://www.readbyqxmd.com/read/29582579/3d-interconnected-mesoporous-alumina-with-loaded-hemoglobin-as-a-highly-active-electrochemical-biosensor-for-h-2-o-2
#19
Xuanyu Yang, Xiaowei Cheng, Hongyuan Song, Junhao Ma, Panpan Pan, Ahmed A Elzatahry, Jiacan Su, Yonghui Deng
Alumina is one of the most common and stable metal oxides in nature, which has been developed as a novel adsorbent in enrichment of biomolecules due to its excellent affinity to phosphor or amino groups. In this study, ordered mesoporous alumina (OMA) with interconnected mesopores and surface acidic property is synthesized through a solvent evaporation induced co-assembly process using poly(ethylene oxide)-b-polystyrene (PEO-b-PS) diblock copolymer as a template and aluminium acetylacetonate (Al(acac)3 ) as the aluminium source...
March 27, 2018: Advanced Healthcare Materials
https://www.readbyqxmd.com/read/29572082/correlation-of-tricuspid-regurgitation-and-new-pacemaker-implantation-in-patients-undergoing-transcatheter-aortic-valve-implantation
#20
Dimitry Schewel, Jury Schewel, Michael Schlüter, Felix Kreidel, Tobias Schmidt, Michael Schmoeckel, Albrecht Elsässer, Karl-Heinz Kuck, Christian Frerker
AIMS: Conduction abnormalities (CA), in particular complete atrioventricular block (CAVB), requiring permanent pacemaker (PPM) implantation, are frequent complications after transcatheter aortic valve implantation (TAVI) in patients with severe aortic stenosis (AS). However, the potential mechanisms are still incompletely understood. The objective of this retrospective study was to determine further predictors of CAVB after TAVI in patients without the known predictors. METHODS AND RESULTS: This study included patients without prior CA/PPM who underwent TAVI of a balloon-expandable valve (Sapien or Sapien XT or Sapien 3)...
June 15, 2018: International Journal of Cardiology
keyword
keyword
49671
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"