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https://www.readbyqxmd.com/read/28655156/comparison-of-latest-generation-transfemoral-self-expandable-and-balloon-expandable-transcatheter-heart-valves
#1
Andreas Schaefer, Matthias Linder, Moritz Seiffert, Gerhard Schoen, Florian Deuschl, Niklas Schofer, Yvonne Schneeberger, Stefan Blankenberg, Hermann Reichenspurner, Ulrich Schaefer, Lenard Conradi
OBJECTIVES: We herein aimed to compare acute 30-day outcomes of latest-generation self-expandable and balloon-expandable transcatheter heart valves. METHODS: From 2012 through 2016, 104 consecutive patients (study group, 69.2% female, 81.7 ± 5.5 years, logEuroSCORE I 15.9 ± 9.3%) received transfemoral transcatheter aortic valve implantation using the Symetis ACURATE neo ® transcatheter heart valve. A control group of patients after transfemoral transcatheter aortic valve implantation with the Edwards Sapien 3™ transcatheter heart valve was retrieved from our database and matched to the study group...
June 26, 2017: Interactive Cardiovascular and Thoracic Surgery
https://www.readbyqxmd.com/read/28544015/transfemoral-transcatheter-acurate-neo%C3%A2-aortic-valve-replacement-in-a-patient-with-a-previous-mechanical-mitral-valve
#2
Rodrigo Bagur, Vincenzo Pestrichella, Rosamaria Montesanti, Rossella Alemanni, Mauro Cassese
Transcatheter aortic valve replacement (TAVR) in the presence of a mechanical mitral valve (MMV) prosthesis is challenging due to the stiff mitral cage in the boundaries of the aorto-mitral curtain. We describe the technique for TAVR using the ACURATE-neo™ aortic bioprosthesis in a patient with a MMV prosthesis.
May 24, 2017: Journal of Cardiac Surgery
https://www.readbyqxmd.com/read/28458227/a-sensitive-and-validated-immunomagnetic-bead-based-enzyme-linked-immunosorbent-assay-for-analyzing-total-t-2-free-and-modified-toxins-in-shrimp-tissues
#3
Qi Deng, Mei Qiu, Yaling Wang, Pengli Lv, Chaojin Wu, Lijun Sun, Riying Ye, Defeng Xu, Ying Liu, Ravi Gooneratne
Accurate analyses of total T-2 (free and modified) in aquatic organisms including shrimp are important as the hazard caused by T-2 has been caught increasing attention. Therefore, acurate analysis of free T-2 especially of modified T-2 in shrimp tissues is important. A rapid, sensitive, and validated method for quantitative determination of free T-2 and modified T-2 toxin was developed using immunomagnetic-bead based enzyme-linked immunosorbent assay (IMB-ELISA). Super paramagnetic particles with a carboxyl group activated by an ester method coupled with envelope antigen 3- acetylneosolaniol- hemisuccinate - ovalbumin (3-Ac-NEOS-HS-OVA) was used to form immunomagnetic beads which could bind to T-2 skeletal structure antibodies...
August 2017: Ecotoxicology and Environmental Safety
https://www.readbyqxmd.com/read/28296065/direct-percutaneous-transaxillary-implantation-of-a-novel-self-expandable-transcatheter-heart-valve-for-aortic-stenosis
#4
Florian Deuschl, Niklas Schofer, Moritz Seiffert, Samer Hakmi, Isamu Mizote, Andreas Schaefer, Johannes Schirmer, Hermann Reichenspurner, Stefan Blankenberg, Lenard Conradi, Ulrich Schäfer
OBJECTIVES: The aim of this study was to evaluate safety, feasibility, and efficacy of transaxillary TAVI using a novel self-expandable transcatheter heart valve (THV) via a direct percutaneous technique. METHODS: The analysis comprises 12 consecutive patients with severe aortic stenosis treated with the ACURATE Neo™ THV (Symetis) by direct percutaneous transaxillary access. RESULTS: Patients presented with a mean age of 79.9 ± 6.2 years and high calculated surgical risk (logEuroSCORE I: 19...
March 15, 2017: Catheterization and Cardiovascular Interventions
https://www.readbyqxmd.com/read/28175264/transcatheter-aortic-valve-implantation-using-the-acurate-ta%C3%A2-system-1-year-outcomes-and-comparison-of-500-patients-from-the-savi-registries
#5
Jochen Börgermann, David M Holzhey, Matthias Thielmann, Evaldas Girdauskas, Holger Schroefel, Steffen Hofmann, Hendrik Treede, Klaus Matschke, Michael Hilker, Justus T Strauch, Thierry Carrel, Thorsten Wahlers, Anno Diegeler, Jörg Kempfert, Thomas Walther
OBJECTIVES: The ACURATE TA TM system is a self-expanding transcatheter heart valve system designed for transapical access which has been proven to be safe and effective in the controlled setting of clinical trials. The SAVI-1 and SAVI-2 registries aimed to assess whether these promising outcomes can be translated into all-comers clinical routine. METHODS: From November 2011 to 2012 (SAVI-1), and November 2013 to 2014 (SAVI-2), a total of 500 patients were enrolled in the prospective, all-comers, multicentre, multinational SAVI registries...
May 1, 2017: European Journal of Cardio-thoracic Surgery
https://www.readbyqxmd.com/read/28169214/transcatheter-aortic-valve-implantation-using-the-acurate-ta%C3%A2-and-acurate-neo-valves-a-4-year-single-center-experience
#6
Karsten Hamm, Wilko Reents, Michael Zacher, Sebastian Kerber, Anno Diegeler, Bernhard Schieffer, Sebastian Barth
AIMS: Long-term outcomes are available for first-generation transcatheter heart valves, but data on second-generation devices are scarce. We aim to provide an oversight of all patients implanted with a second-generation valve in our center. METHODS AND RESULTS: From April 2012 to July 2016, 219 patients were enrolled in this prospective single-center experience; they received either the transapical ACURATE TA™ (n=99) or the transfemoral ACURATE neo™ (n=120) prosthesis...
February 7, 2017: EuroIntervention
https://www.readbyqxmd.com/read/28073571/early-clinical-outcomes-of-a-novel-self-expanding-transapical-transcatheter-aortic-valve-bioprosthesis
#7
Michael W A Chu, Rodrigo Bagur, Katie L Losenno, Philip M Jones, Pantelis Diamantouros, Patrick Teefy, Jill J Gelinas, Bob Kiaii
OBJECTIVE: Coronary obstruction remains a challenging complication of transcatheter aortic valve replacement; however, a new self-expanding transapical prosthesis may reduce this risk. The purpose of this study was to evaluate the early 1-year outcomes of patients with low coronary heights who received the Acurate TA bioprosthesis (Symetis, Ecublens, Switzerland). METHODS: Between May 2014 and April 2015, 30 consecutive patients (aged 85 ± 6 years, 63% were female, Society of Thoracic Surgeons score 8...
April 2017: Journal of Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/28029207/prospective-comparison-between-three-tavr-devices-acurate-neo-vs-corevalve-vs-sapien-xt-a-single-heart-team-experience-in-patients-with-severe-aortic-stenosis
#8
Tannas Jatene, Antonio Castro-Filho, Rafael A Meneguz-Moreno, Dimytri A Siqueira, Alexandre A C Abizaid, Auristela I O Ramos, Magaly Arrais, David C S Le Bihan, Rodrigo B M Barretto, Adriana C Moreira, Amanda G M R Sousa, J Eduardo Sousa
OBJECTIVE: We sought to compare the new transcatheter aortic valve replacement (TAVR) device ACURATE neo (ACT) with the already established CoreValve (MCV) and SAPIEN XT (SXT) for the treatment of severe aortic stenosis (AS). BACKGROUND: Very few data on TAVR devices are available beyond MCV and SAPIEN and there is no previous study comparing ACT with MCV and SXT. METHODS: We prospectively evaluated consecutive patients who underwent transfemoral TAVR for the treatment of severe AS...
July 2017: Catheterization and Cardiovascular Interventions
https://www.readbyqxmd.com/read/27872440/successful-percutaneous-implantation-of-symetis-acurate-neo-transcatheter-aortic-bioprosthesis-in-a-patient-with-existing-mechanical-mitral-valve
#9
Sina Ali, Yakup Alsancak, Mustafa Duran, Mehmet Bilge
No abstract text is available yet for this article.
November 2016: Anatolian Journal of Cardiology
https://www.readbyqxmd.com/read/27692823/transcaval-transcatheter-aortic-valve-replacement-with-the-acurate-neo-aortic-bioprosthesis-first-north-american%C3%A2-experience
#10
Rodrigo Bagur, Patrick J Teefy, Bob Kiaii, Aashish Goela, Adam Greenbaum, Michael W A Chu
No abstract text is available yet for this article.
October 24, 2016: JACC. Cardiovascular Interventions
https://www.readbyqxmd.com/read/27677241/first-north-american-experience-with-the-transfemoral-acurate-neo-tm-self-expanding-transcatheter-aortic-bioprosthesis
#11
Rodrigo Bagur, Patrick J Teefy, Bob Kiaii, Pantelis Diamantouros, Michael W A Chu
BACKGROUND: Transcatheter aortic valve implantation (TAVI) has become a therapeutic alternative for patients presenting with severe symptomatic aortic stenosis and considered at high-surgical risk. Paravalvular leak (PVL), conduction disorders, and coronary obstruction remain unresolved procedure-related complications. The aim of this manuscript was to report the first North American experience with the ACURATE-neo(TM) aortic bioprosthesis and its ACURATE-TF(TM) delivery system (Symetis S...
July 2017: Catheterization and Cardiovascular Interventions
https://www.readbyqxmd.com/read/27585056/readmission-to-the-acute-care-unit-and-functional-outcomes-in-patients-with-severe-brain-injury-during-rehabilitation
#12
Domenico Intiso, Andrea Fontana, Giuseppe Maruzzi, Maurizio Tolfa, Massimiliano Copetti, Filomena DI Rienzo
BACKGROUND: Medical and surgical complications are common after brain lesions and may require acute care unit readmission (ACUR) during the rehabilitation stay. This clinical phenomenon has not been explored in subjects with severe brain injury (sBI). AIM: Because sBI patients come from the intensive care unit (ICU), patients may be transferred to rehabilitation before complete clinical stabilization. We investigated ACUR and causes as well as whether those who required ACUR had different functional outcomes...
April 2017: European Journal of Physical and Rehabilitation Medicine
https://www.readbyqxmd.com/read/27502129/-transcatheter-aortic-valve-replacement-the-new-era-new-opportunity-and-new-challenge-of-cardiac-surgery
#13
L Wei, Y Yang, C S Wang, H Liu
Conventional surgical aortic valve replacement is still the current "gold standard" in treatment of aortic valve disease, but part of the high-risk elder patients couldn't tolerate the surgical trauma. Now those people could receive timely and effective treatment with the application of transcatheter aortic valve replacement, and the related guidelines have been published in recent years. With its wide use in recent 10 years, different implantation systems, such as SAPIEN, CoreValve, Lotus, ACURATE neo, have been gradually improved and provened in several large clinical trials...
August 1, 2016: Zhonghua Wai Ke za Zhi [Chinese Journal of Surgery]
https://www.readbyqxmd.com/read/27173866/first-in-man-transfemoral-transcatheter-aortic-valve-implantation-with-the-acurate-neo-for-the-treatment-of-aortic-regurgitation
#14
Stefan Toggweiler, Patric Biaggi, Jürg Grünenfelder, Ivan Reho, Ines Bühler, Roberto Corti
No abstract text is available yet for this article.
May 17, 2016: EuroIntervention
https://www.readbyqxmd.com/read/26888463/improving-outcomes-case-matched-comparison-of-novel-second-generation-versus-first-generation-self-expandable-transcatheter-heart-valves
#15
Andreas Schaefer, Hendrik Treede, Gerhard Schoen, Florian Deuschl, Niklas Schofer, Yvonne Schneeberger, Stefan Blankenberg, Hermann Reichenspurner, Ulrich Schaefer, Lenard Conradi
OBJECTIVES: The published literature has extensively documented clinical benefit derived from transcatheter aortic valve implantation (TAVI) in high-risk patients using self-expanding current-generation transfemoral (TF) transcatheter heart valves (THVs). However, it has also demonstrated apparent shortcomings such as paravalvular leakage (PVL) or need for permanent pacemaker (PM) implantation. We here present a case-matched analysis of acute 30-day outcomes using a novel nitinol-based THV (Symetis Acurate Neo TF™), which may overcome some limitations of currently used devices...
August 2016: European Journal of Cardio-thoracic Surgery
https://www.readbyqxmd.com/read/26762474/successful-percutaneous-implantation-of-symetis-acurate-neo-transcatheter-aortic-bioprosthesis-for-the-treatment-of-pure-aortic-regurgitation
#16
Alfredo Giuseppe Cerillo, Daniel Griese, Sergio Berti
Transcatheter aortic valve implantation (TAVI) was initially developed for the treatment of calcific aortic stenosis. In the recent years, however, TAVI has been used to treat selected patients with pure, severe AR. We report successful transfemoral implantation of a Symetis ACURATE neo bioprosthesis in a severely symptomatic, 87-year-old woman with pure AR and major comorbidities. We decided to use the ACURATE neo bioprosthesis for some of its features appeared to us as potentially useful in the setting of pure AR: the stabilization arches ensure perfect coaxial alignment and extreme stability of the device during deployment, and the "waist" and the skirt were considered useful to obtain a good seal in the absence of significant valvular and annular calcifications...
August 2016: Catheterization and Cardiovascular Interventions
https://www.readbyqxmd.com/read/26593630/a-biphasic-transversely-isotropic-poroviscoelastic-model-for-the-unconfined-compression-of-hydrated-soft-tissue
#17
H Hatami-Marbini, R Maulik
The unconfined compression experiments are commonly used for characterizing the mechanical behavior of hydrated soft tissues such as articular cartilage. Several analytical constitutive models have been proposed over the years to analyze the unconfined compression experimental data and subsequently estimate the material parameters. Nevertheless, new mathematical models are still required to obtain more accurate numerical estimates. The present study aims at developing a linear transversely isotropic poroviscoelastic theory by combining a viscoelastic material law with the transversely isotropic biphasic model...
March 2016: Journal of Biomechanical Engineering
https://www.readbyqxmd.com/read/26522576/transcatheter-acurate-ta-aortic-valve-implantation-in-a-patient-with-a-previous-mechanical-mitral-valve
#18
Rodrigo Bagur, Bob Kiaii, Patrick J Teefy, Pantelis Diamantouros, Christopher Harle, Aashish Goela, Ian Chan, Michael W A Chu
Transcatheter aortic valve implantation (TAVI) in the presence of a mechanical mitral valve (MMV) prosthesis is still challenging because of the rigid mitral frame within the aortomitral curtain. Moreover, low-lying coronary ostia represent a hazardous problem of coronary obstruction, especially in narrow or porcelain aortic roots. The present case demonstrates the successful management of 2 challenging anatomical issues, the rigid cage of the MMV and the low-lying left main coronary ostium (LMCO), with the implantation of the ACURATE-TA bioprosthesis (Symetis SA, Ecublens, Switzerland)...
November 2015: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/26424553/salvaging-lowermost-deployment-of-an-acurate-device-during-transcatheter-aortic-valve-replacement-with-balloon-and-lasso-pull-techniques
#19
Nicola Corcione, Giuseppe Biondi-Zoccai, Arturo Giordano
Transcatheter aortic valve replacement (TAVR), also known as transcatheter aortic valve implantation (TAVI), is being used with increasing frequency in patients with severe aortic stenosis at high or prohibitive surgical risk. A number of devices are becoming available for TAVR, and competence in using them is mandatory to maximize the safety and efficacy of TAVR, while individualizing device selection in keeping with patient features. The ACURATE TF is a novel promising device for transfemoral TAVR. However, its peculiar features may require additional maneuvers in case of complications...
September 2016: Catheterization and Cardiovascular Interventions
https://www.readbyqxmd.com/read/26198875/symetis-acurate-tavi-review-of-the-technology-developments-and-current-data-with-this-self-expanding-transcatheter-heart-valve
#20
REVIEW
U Schäfer, L Conradi, P Diemert, F Deuschl, N Schofer, M Seiffert, E Lubos, J Schirmer, H Reichenspurner, S Blankenberg, H Treede
The Symetis ACURATE TA and ACURATE neo technology is a novel transcatheter heart valve for treatment of aortic valvular stenosis. This review illustrates the implantation steps, which are designed for an easy and intuitive transapical and transfemoral TAVI procedure. The most important difference to other self-expanding platforms is the top-down deployment with minimal protrusion of the stent towards the left ventricular outflow tract. In addition, the supra-annularly placed porcine leaflets provide very low gradients and the pericardial skirt acts very effectively to seal against paravalvular leaks...
October 2015: Minerva Cardioangiologica
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