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https://www.readbyqxmd.com/read/29131801/real-world-experience-using-the-acurate-neo%C3%A2-prosthesis-30-day-outcomes-of-1000-patients-enrolled-in-the-savi-tf-registry
#1
Helge Möllmann, Christian Hengstenberg, Michael Hilker, Sebastian Kerber, Ulrich Schäfer, Tanja Rudolph, Axel Linke, Norbert Franz, Thomas Kuntze, Holger Nef, Utz Kappert, Thomas Walther, Michael O Zembala, Stefan Toggweiler, Won-Keun Kim
AIMS: The aim of the SAVI-TF registry was to assess the safety and performance of the self-expanding ACURATE neoTM transfemoral transcatheter heart valve in a large patient population with severe aortic stenosis and to investigate if the outcomes obtained in the CE-mark cohort can be replicated in an unselected all-comers population. METHODS AND RESULTS: From October 2014 until April 2016, 1000 patients were enrolled in this prospective, European multicenter registry...
November 14, 2017: EuroIntervention
https://www.readbyqxmd.com/read/29126972/initial-experience-in-the-iberian-peninsula-with-the-transfemoral-acurate-neo-tf-transcatheter-aortic-prosthesis-procedure-and-outcomes
#2
Diego López-Otero, João Gonçalves Almeida, Luis Nombela Franco, Pilar Jiménez-Quevedo, Vasco Gama Ribeiro, Ramiro Trillo-Nouche
No abstract text is available yet for this article.
November 7, 2017: Revista Española de Cardiología
https://www.readbyqxmd.com/read/29105687/-early-and-mid-term-results-of-the-transapical-aortic-valve-symetis-acurate-ta-a-viable-solution-in-high-risk-patients-with-severe-vascular-disease
#3
Giuseppe Rescigno, Maria Giovanna Fratesi, Carlo Aratari, Stefano Moretti, Filippo Capestro, Massimiliano Serenelli, Luca Piangerelli, Anca Delca, Gian Piero Perna, Alessandro Capucci, Marco Di Eusanio
BACKGROUND: Aortic valve stenosis is the most common valvular disease in the elderly. Transcatheter aortic valve implantation represents a viable alternative to conventional aortic valve replacement. In our Department, the transapical approach is the preferred method in patients with severe peripheral vascular disease. The aim of this study was to analyze the early and midterm results of Symetis Acurate TA implantation in our series. METHODS: From June 2013 to January 2017, 21 patients with severe peripheral vascular disease (11 male, mean age 78 ± 2...
October 2017: Giornale Italiano di Cardiologia
https://www.readbyqxmd.com/read/29050626/a-comparison-of-the-acurate-neo-and-sapien-3-valves-making-progress
#4
EDITORIAL
Kreton Mavromatis
No abstract text is available yet for this article.
October 23, 2017: JACC. Cardiovascular Interventions
https://www.readbyqxmd.com/read/29050625/multicenter-comparison-of-novel-self-expanding-versus-balloon-expandable-transcatheter-heart%C3%A2-valves
#5
Oliver Husser, Won-Keun Kim, Costanza Pellegrini, Andreas Holzamer, Thomas Walther, Patrick N Mayr, Michael Joner, Albert M Kasel, Teresa Trenkwalder, Jonathan Michel, Tobias Rheude, Adnan Kastrati, Heribert Schunkert, Christof Burgdorf, Michael Hilker, Helge Möllmann, Christian Hengstenberg
OBJECTIVES: This study sought to compare 2 next-generation transcatheter heart valves (THV), the self-expanding ACURATE neo (NEO) and the balloon-expandable SAPIEN 3 (S3), in terms of device failure and early safety at 30 days. BACKGROUND: Deployment of these THV showed promising initial clinical results. However, no comparative data are available. METHODS: Of 1,121 treated patients at 3 centers, a 1-to-2 nearest neighbor matching was performed to identify 2 patients treated with S3 (n = 622) for each patient treated with NEO (n = 311)...
October 23, 2017: JACC. Cardiovascular Interventions
https://www.readbyqxmd.com/read/28951395/short-term-outcome-and-hemodynamic-performance-of-next-generation-self-expanding-versus-balloon-expandable-transcatheter-aortic-valves-in-patients-with-small-aortic-annulus-a-multicenter-propensity-matched-comparison
#6
Victor Mauri, Won K Kim, Mohammad Abumayyaleh, Thomas Walther, Helge Moellmann, Ulrich Schaefer, Lenard Conradi, Christian Hengstenberg, Michael Hilker, Thorsten Wahlers, Stephan Baldus, Volker Rudolph, Navid Madershahian, Tanja K Rudolph
BACKGROUND: Surgical aortic valve replacement in patients with small annular dimensions is challenging because they are at increased risk for prosthesis-patient mismatch and impaired outcomes. Transcatheter aortic valve replacement might be a good alternative; however, comparative data on different transcatheter heart valves are missing. METHODS AND RESULTS: This multicenter, propensity score-matched study compared hemodynamics and early clinical outcomes in 246 patients with an aortic annulus area <400 mm(2) undergoing transcatheter aortic valve replacement with either a self-expanding transcatheter heart valve (Symetis ACURATE neo, n=129) or a balloon-expandable transcatheter heart valve (Edwards SAPIEN 3, n=117)...
October 2017: Circulation. Cardiovascular Interventions
https://www.readbyqxmd.com/read/28885378/radial-force-an-underestimated-parameter-in-oversizing-transcatheter-aortic-valve-replacement-prostheses-in-vitro-analysis-with-five-commercialized-valves
#7
Sandrine Egron, Buntaro Fujita, Lucía Gullón, Pott Désirée, Thomas Schmitz-Rode, Stephan Ensminger, Ulrich Steinseifer
The goal is to inform in depth on transcatheter aortic valve replacement (TAVR) prosthesis mechanical behavior, depending on frame type, design, and size, and how it crucially impacts the oversizing issue in clinical use, and ultimately the procedure outcome. Transcatheter aortic valve replacement is an established therapy for high-risk patients suffering from aortic stenosis, and the indication for TAVR is progressively expanding to intermediate-risk patients. Choosing the optimal oversizing degree is crucial to safely anchor the TAVR valve-which involves limiting the risks for embolism, aortic regurgitation, conductance disturbance, or annulus rupture-and to increase the valve prosthesis performance...
September 5, 2017: ASAIO Journal: a Peer-reviewed Journal of the American Society for Artificial Internal Organs
https://www.readbyqxmd.com/read/28870877/very-low-pacemaker-rate-following-acurate-neo-transcatheter-heart-valve-implantation
#8
Stefan Toggweiler, Henrik Nissen, Brynjolfur Mogensen, Florim Cuculi, Christian Fallesen, Karsten Tange Veien, Miriam Brinkert, Richard Kobza, Andreas Rück
AIMS: Investigate if minimizing trauma to the aortic annulus and left ventricular outflow tract reduces the occurrence of new conduction disorders and need for permanent pacemakers. METHODS AND RESULTS: A total of 175 patients (58% women, mean age 83 ± 6 years) underwent transfemoral TAVI with the Boston Scientific ACURATE neo at three centers in Europe. Prosthesis size selection was based on perimeter derived annular diameter. Predilatation was performed in all with a balloon 1...
September 5, 2017: EuroIntervention
https://www.readbyqxmd.com/read/28804056/transfemoral-tavi-using-the-self-expandable-acurate-neo-tm-prosthesis-one-year-outcomes-of-the-multicenter-ce-approval-cohort
#9
Helge Möllmann, Thomas Walther, Dimytri Siqueira, Patrick Diemert, Hendrik Treede, Eberhard Grube, Georg Nickenig, Stephan Baldus, Tanja Rudolph, Toru Kuratani, Yoshiki Sawa, Joerg Kempfert, Won-Keun Kim, Alexandre Abizaid
AIMS: The aim of this study was to assess the safety and performance of the ACURATE neoTM transcatheter heart valve and its transfemoral delivery system. METHODS AND RESULTS: The prospective, multi-center "CE-approval cohort" consists of a prospective series of the first 89 patients implanted with the ACURATE neoTM prosthesis. The primary endpoint was all-cause mortality at 30 days. Mean patient age was 83.7±4.4 years and logistic EuroSCORE-I was 26.5±7.7%. Procedural success was obtained in 84 patients (94...
August 15, 2017: EuroIntervention
https://www.readbyqxmd.com/read/28760396/transcatheter-aortic-valve-replacement-with-new-generation-devices-a-systematic-review-and-meta-analysis
#10
Marco Barbanti, Sergio Buccheri, Josep Rodés-Cabau, Simona Gulino, Philippe Généreux, Gerlando Pilato, Danny Dvir, Andrea Picci, Giuliano Costa, Corrado Tamburino, Martin B Leon, John G Webb
OBJECTIVE: The aim of this study was to conduct a weighted meta-analysis to determine the rates of acute (≤30days) major outcomes after (TAVR) with second-generation devices. METHODS: A comprehensive search of multiple electronic databases from January 2011 to May 2017 was conducted using predefined criteria. New-generation TAVR devices were defined as any device which received CE mark approval or is still under evaluation for CE marking after CoreValve and SAPIEN XT prostheses...
October 15, 2017: International Journal of Cardiology
https://www.readbyqxmd.com/read/28655156/comparison-of-latest-generation-transfemoral-self-expandable-and-balloon-expandable-transcatheter-heart-valves
#11
Andreas Schaefer, Matthias Linder, Moritz Seiffert, Gerhard Schoen, Florian Deuschl, Niklas Schofer, Yvonne Schneeberger, Stefan Blankenberg, Hermann Reichenspurner, Ulrich Schaefer, Lenard Conradi
OBJECTIVES: We herein aimed to compare acute 30-day outcomes of latest-generation self-expandable and balloon-expandable transcatheter heart valves. METHODS: From 2012 through 2016, 104 consecutive patients (study group, 69.2% female, 81.7 ± 5.5 years, logEuroSCORE I 15.9 ± 9.3%) received transfemoral transcatheter aortic valve implantation using the Symetis ACURATE neo ® transcatheter heart valve. A control group of patients after transfemoral transcatheter aortic valve implantation with the Edwards Sapien 3™ transcatheter heart valve was retrieved from our database and matched to the study group...
June 26, 2017: Interactive Cardiovascular and Thoracic Surgery
https://www.readbyqxmd.com/read/28544015/transfemoral-transcatheter-acurate-neo%C3%A2-aortic-valve-replacement-in-a-patient-with-a-previous-mechanical-mitral-valve
#12
Rodrigo Bagur, Vincenzo Pestrichella, Rosamaria Montesanti, Rossella Alemanni, Mauro Cassese
Transcatheter aortic valve replacement (TAVR) in the presence of a mechanical mitral valve (MMV) prosthesis is challenging due to the stiff mitral cage in the boundaries of the aorto-mitral curtain. We describe the technique for TAVR using the ACURATE-neo™ aortic bioprosthesis in a patient with a MMV prosthesis.
June 2017: Journal of Cardiac Surgery
https://www.readbyqxmd.com/read/28458227/a-sensitive-and-validated-immunomagnetic-bead-based-enzyme-linked-immunosorbent-assay-for-analyzing-total-t-2-free-and-modified-toxins-in-shrimp-tissues
#13
Qi Deng, Mei Qiu, Yaling Wang, Pengli Lv, Chaojin Wu, Lijun Sun, Riying Ye, Defeng Xu, Ying Liu, Ravi Gooneratne
Accurate analyses of total T-2 (free and modified) in aquatic organisms including shrimp are important as the hazard caused by T-2 has been caught increasing attention. Therefore, acurate analysis of free T-2 especially of modified T-2 in shrimp tissues is important. A rapid, sensitive, and validated method for quantitative determination of free T-2 and modified T-2 toxin was developed using immunomagnetic-bead based enzyme-linked immunosorbent assay (IMB-ELISA). Super paramagnetic particles with a carboxyl group activated by an ester method coupled with envelope antigen 3- acetylneosolaniol- hemisuccinate - ovalbumin (3-Ac-NEOS-HS-OVA) was used to form immunomagnetic beads which could bind to T-2 skeletal structure antibodies...
August 2017: Ecotoxicology and Environmental Safety
https://www.readbyqxmd.com/read/28296065/direct-percutaneous-transaxillary-implantation-of-a-novel-self-expandable-transcatheter-heart-valve-for-aortic-stenosis
#14
Florian Deuschl, Niklas Schofer, Moritz Seiffert, Samer Hakmi, Isamu Mizote, Andreas Schaefer, Johannes Schirmer, Hermann Reichenspurner, Stefan Blankenberg, Lenard Conradi, Ulrich Schäfer
OBJECTIVES: The aim of this study was to evaluate safety, feasibility, and efficacy of transaxillary TAVI using a novel self-expandable transcatheter heart valve (THV) via a direct percutaneous technique. METHODS: The analysis comprises 12 consecutive patients with severe aortic stenosis treated with the ACURATE Neo™ THV (Symetis) by direct percutaneous transaxillary access. RESULTS: Patients presented with a mean age of 79.9 ± 6.2 years and high calculated surgical risk (logEuroSCORE I: 19...
March 15, 2017: Catheterization and Cardiovascular Interventions
https://www.readbyqxmd.com/read/28175264/transcatheter-aortic-valve-implantation-using-the-acurate-ta%C3%A2-system-1-year-outcomes-and-comparison-of-500-patients-from-the-savi-registries
#15
Jochen Börgermann, David M Holzhey, Matthias Thielmann, Evaldas Girdauskas, Holger Schroefel, Steffen Hofmann, Hendrik Treede, Klaus Matschke, Michael Hilker, Justus T Strauch, Thierry Carrel, Thorsten Wahlers, Anno Diegeler, Jörg Kempfert, Thomas Walther
OBJECTIVES: The ACURATE TA TM system is a self-expanding transcatheter heart valve system designed for transapical access which has been proven to be safe and effective in the controlled setting of clinical trials. The SAVI-1 and SAVI-2 registries aimed to assess whether these promising outcomes can be translated into all-comers clinical routine. METHODS: From November 2011 to 2012 (SAVI-1), and November 2013 to 2014 (SAVI-2), a total of 500 patients were enrolled in the prospective, all-comers, multicentre, multinational SAVI registries...
May 1, 2017: European Journal of Cardio-thoracic Surgery
https://www.readbyqxmd.com/read/28169214/transcatheter-aortic-valve-implantation-using-the-acurate-ta%C3%A2-and-acurate-neo-valves-a-4-year-single-center-experience
#16
Karsten Hamm, Wilko Reents, Michael Zacher, Sebastian Kerber, Anno Diegeler, Bernhard Schieffer, Sebastian Barth
AIMS: Long-term outcomes are available for first-generation transcatheter heart valves, but data on second-generation devices are scarce. We aim to provide an oversight of all patients implanted with a second-generation valve in our center. METHODS AND RESULTS: From April 2012 to July 2016, 219 patients were enrolled in this prospective single-center experience; they received either the transapical ACURATE TA™ (n=99) or the transfemoral ACURATE neo™ (n=120) prosthesis...
February 7, 2017: EuroIntervention
https://www.readbyqxmd.com/read/28073571/early-clinical-outcomes-of-a-novel-self-expanding-transapical-transcatheter-aortic-valve-bioprosthesis
#17
Michael W A Chu, Rodrigo Bagur, Katie L Losenno, Philip M Jones, Pantelis Diamantouros, Patrick Teefy, Jill J Gelinas, Bob Kiaii
OBJECTIVE: Coronary obstruction remains a challenging complication of transcatheter aortic valve replacement; however, a new self-expanding transapical prosthesis may reduce this risk. The purpose of this study was to evaluate the early 1-year outcomes of patients with low coronary heights who received the Acurate TA bioprosthesis (Symetis, Ecublens, Switzerland). METHODS: Between May 2014 and April 2015, 30 consecutive patients (aged 85 ± 6 years, 63% were female, Society of Thoracic Surgeons score 8...
April 2017: Journal of Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/28029207/prospective-comparison-between-three-tavr-devices-acurate-neo-vs-corevalve-vs-sapien-xt-a-single-heart-team-experience-in-patients-with-severe-aortic-stenosis
#18
Tannas Jatene, Antonio Castro-Filho, Rafael A Meneguz-Moreno, Dimytri A Siqueira, Alexandre A C Abizaid, Auristela I O Ramos, Magaly Arrais, David C S Le Bihan, Rodrigo B M Barretto, Adriana C Moreira, Amanda G M R Sousa, J Eduardo Sousa
OBJECTIVE: We sought to compare the new transcatheter aortic valve replacement (TAVR) device ACURATE neo (ACT) with the already established CoreValve (MCV) and SAPIEN XT (SXT) for the treatment of severe aortic stenosis (AS). BACKGROUND: Very few data on TAVR devices are available beyond MCV and SAPIEN and there is no previous study comparing ACT with MCV and SXT. METHODS: We prospectively evaluated consecutive patients who underwent transfemoral TAVR for the treatment of severe AS...
July 2017: Catheterization and Cardiovascular Interventions
https://www.readbyqxmd.com/read/27872440/successful-percutaneous-implantation-of-symetis-acurate-neo-transcatheter-aortic-bioprosthesis-in-a-patient-with-existing-mechanical-mitral-valve
#19
Sina Ali, Yakup Alsancak, Mustafa Duran, Mehmet Bilge
No abstract text is available yet for this article.
November 2016: Anatolian Journal of Cardiology
https://www.readbyqxmd.com/read/27692823/transcaval-transcatheter-aortic-valve-replacement-with-the-acurate-neo-aortic-bioprosthesis-first-north-american%C3%A2-experience
#20
Rodrigo Bagur, Patrick J Teefy, Bob Kiaii, Aashish Goela, Adam Greenbaum, Michael W A Chu
No abstract text is available yet for this article.
October 24, 2016: JACC. Cardiovascular Interventions
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