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https://www.readbyqxmd.com/read/28885378/radial-force-an-underestimated-parameter-in-oversizing-transcatheter-aortic-valve-replacement-prostheses-in-vitro-analysis-with-five-commercialized-valves
#1
Sandrine Egron, Buntaro Fujita, Lucía Gullón, Pott Désirée, Thomas Schmitz-Rode, Stephan Ensminger, Ulrich Steinseifer
The goal is to inform in depth on transcatheter aortic valve replacement (TAVR) prosthesis mechanical behavior, depending on frame type, design, and size, and how it crucially impacts the oversizing issue in clinical use, and ultimately the procedure outcome. Transcatheter aortic valve replacement is an established therapy for high-risk patients suffering from aortic stenosis, and the indication for TAVR is progressively expanding to intermediate-risk patients. Choosing the optimal oversizing degree is crucial to safely anchor the TAVR valve-which involves limiting the risks for embolism, aortic regurgitation, conductance disturbance, or annulus rupture-and to increase the valve prosthesis performance...
September 5, 2017: ASAIO Journal: a Peer-reviewed Journal of the American Society for Artificial Internal Organs
https://www.readbyqxmd.com/read/28870877/very-low-pacemaker-rate-following-acurate-neo-transcatheter-heart-valve-implantation
#2
Stefan Toggweiler, Henrik Nissen, Brynjolfur Mogensen, Florim Cuculi, Christian Fallesen, Karsten Tange Veien, Miriam Brinkert, Richard Kobza, Andreas Rück
AIMS: Investigate if minimizing trauma to the aortic annulus and left ventricular outflow tract reduces the occurrence of new conduction disorders and need for permanent pacemakers. METHODS AND RESULTS: A total of 175 patients (58% women, mean age 83 ± 6 years) underwent transfemoral TAVI with the Boston Scientific ACURATE neo at three centers in Europe. Prosthesis size selection was based on perimeter derived annular diameter. Predilatation was performed in all with a balloon 1...
September 5, 2017: EuroIntervention
https://www.readbyqxmd.com/read/28804056/transfemoral-tavi-using-the-self-expandable-acurate-neo-tm-prosthesis-one-year-outcomes-of-the-multicenter-ce-approval-cohort
#3
Helge Möllmann, Thomas Walther, Dimytri Siqueira, Patrick Diemert, Hendrik Treede, Eberhard Grube, Georg Nickenig, Stephan Baldus, Tanja Rudolph, Toru Kuratani, Yoshiki Sawa, Joerg Kempfert, Won-Keun Kim, Alexandre Abizaid
AIMS: The aim of this study was to assess the safety and performance of the ACURATE neoTM transcatheter heart valve and its transfemoral delivery system. METHODS AND RESULTS: The prospective, multi-center "CE-approval cohort" consists of a prospective series of the first 89 patients implanted with the ACURATE neoTM prosthesis. The primary endpoint was all-cause mortality at 30 days. Mean patient age was 83.7±4.4 years and logistic EuroSCORE-I was 26.5±7.7%. Procedural success was obtained in 84 patients (94...
August 15, 2017: EuroIntervention
https://www.readbyqxmd.com/read/28760396/transcatheter-aortic-valve-replacement-with-new-generation-devices-a-systematic-review-and-meta-analysis
#4
Marco Barbanti, Sergio Buccheri, Josep Rodés-Cabau, Simona Gulino, Philippe Généreux, Gerlando Pilato, Danny Dvir, Andrea Picci, Giuliano Costa, Corrado Tamburino, Martin B Leon, John G Webb
OBJECTIVE: The aim of this study was to conduct a weighted meta-analysis to determine the rates of acute (≤30days) major outcomes after (TAVR) with second-generation devices. METHODS: A comprehensive search of multiple electronic databases from January 2011 to May 2017 was conducted using predefined criteria. New-generation TAVR devices were defined as any device which received CE mark approval or is still under evaluation for CE marking after CoreValve and SAPIEN XT prostheses...
July 25, 2017: International Journal of Cardiology
https://www.readbyqxmd.com/read/28655156/comparison-of-latest-generation-transfemoral-self-expandable-and-balloon-expandable-transcatheter-heart-valves
#5
Andreas Schaefer, Matthias Linder, Moritz Seiffert, Gerhard Schoen, Florian Deuschl, Niklas Schofer, Yvonne Schneeberger, Stefan Blankenberg, Hermann Reichenspurner, Ulrich Schaefer, Lenard Conradi
OBJECTIVES: We herein aimed to compare acute 30-day outcomes of latest-generation self-expandable and balloon-expandable transcatheter heart valves. METHODS: From 2012 through 2016, 104 consecutive patients (study group, 69.2% female, 81.7 ± 5.5 years, logEuroSCORE I 15.9 ± 9.3%) received transfemoral transcatheter aortic valve implantation using the Symetis ACURATE neo ® transcatheter heart valve. A control group of patients after transfemoral transcatheter aortic valve implantation with the Edwards Sapien 3™ transcatheter heart valve was retrieved from our database and matched to the study group...
June 26, 2017: Interactive Cardiovascular and Thoracic Surgery
https://www.readbyqxmd.com/read/28544015/transfemoral-transcatheter-acurate-neo%C3%A2-aortic-valve-replacement-in-a-patient-with-a-previous-mechanical-mitral-valve
#6
Rodrigo Bagur, Vincenzo Pestrichella, Rosamaria Montesanti, Rossella Alemanni, Mauro Cassese
Transcatheter aortic valve replacement (TAVR) in the presence of a mechanical mitral valve (MMV) prosthesis is challenging due to the stiff mitral cage in the boundaries of the aorto-mitral curtain. We describe the technique for TAVR using the ACURATE-neo™ aortic bioprosthesis in a patient with a MMV prosthesis.
May 24, 2017: Journal of Cardiac Surgery
https://www.readbyqxmd.com/read/28458227/a-sensitive-and-validated-immunomagnetic-bead-based-enzyme-linked-immunosorbent-assay-for-analyzing-total-t-2-free-and-modified-toxins-in-shrimp-tissues
#7
Qi Deng, Mei Qiu, Yaling Wang, Pengli Lv, Chaojin Wu, Lijun Sun, Riying Ye, Defeng Xu, Ying Liu, Ravi Gooneratne
Accurate analyses of total T-2 (free and modified) in aquatic organisms including shrimp are important as the hazard caused by T-2 has been caught increasing attention. Therefore, acurate analysis of free T-2 especially of modified T-2 in shrimp tissues is important. A rapid, sensitive, and validated method for quantitative determination of free T-2 and modified T-2 toxin was developed using immunomagnetic-bead based enzyme-linked immunosorbent assay (IMB-ELISA). Super paramagnetic particles with a carboxyl group activated by an ester method coupled with envelope antigen 3- acetylneosolaniol- hemisuccinate - ovalbumin (3-Ac-NEOS-HS-OVA) was used to form immunomagnetic beads which could bind to T-2 skeletal structure antibodies...
August 2017: Ecotoxicology and Environmental Safety
https://www.readbyqxmd.com/read/28296065/direct-percutaneous-transaxillary-implantation-of-a-novel-self-expandable-transcatheter-heart-valve-for-aortic-stenosis
#8
Florian Deuschl, Niklas Schofer, Moritz Seiffert, Samer Hakmi, Isamu Mizote, Andreas Schaefer, Johannes Schirmer, Hermann Reichenspurner, Stefan Blankenberg, Lenard Conradi, Ulrich Schäfer
OBJECTIVES: The aim of this study was to evaluate safety, feasibility, and efficacy of transaxillary TAVI using a novel self-expandable transcatheter heart valve (THV) via a direct percutaneous technique. METHODS: The analysis comprises 12 consecutive patients with severe aortic stenosis treated with the ACURATE Neo™ THV (Symetis) by direct percutaneous transaxillary access. RESULTS: Patients presented with a mean age of 79.9 ± 6.2 years and high calculated surgical risk (logEuroSCORE I: 19...
March 15, 2017: Catheterization and Cardiovascular Interventions
https://www.readbyqxmd.com/read/28175264/transcatheter-aortic-valve-implantation-using-the-acurate-ta%C3%A2-system-1-year-outcomes-and-comparison-of-500-patients-from-the-savi-registries
#9
Jochen Börgermann, David M Holzhey, Matthias Thielmann, Evaldas Girdauskas, Holger Schroefel, Steffen Hofmann, Hendrik Treede, Klaus Matschke, Michael Hilker, Justus T Strauch, Thierry Carrel, Thorsten Wahlers, Anno Diegeler, Jörg Kempfert, Thomas Walther
OBJECTIVES: The ACURATE TA TM system is a self-expanding transcatheter heart valve system designed for transapical access which has been proven to be safe and effective in the controlled setting of clinical trials. The SAVI-1 and SAVI-2 registries aimed to assess whether these promising outcomes can be translated into all-comers clinical routine. METHODS: From November 2011 to 2012 (SAVI-1), and November 2013 to 2014 (SAVI-2), a total of 500 patients were enrolled in the prospective, all-comers, multicentre, multinational SAVI registries...
May 1, 2017: European Journal of Cardio-thoracic Surgery
https://www.readbyqxmd.com/read/28169214/transcatheter-aortic-valve-implantation-using-the-acurate-ta%C3%A2-and-acurate-neo-valves-a-4-year-single-center-experience
#10
Karsten Hamm, Wilko Reents, Michael Zacher, Sebastian Kerber, Anno Diegeler, Bernhard Schieffer, Sebastian Barth
AIMS: Long-term outcomes are available for first-generation transcatheter heart valves, but data on second-generation devices are scarce. We aim to provide an oversight of all patients implanted with a second-generation valve in our center. METHODS AND RESULTS: From April 2012 to July 2016, 219 patients were enrolled in this prospective single-center experience; they received either the transapical ACURATE TA™ (n=99) or the transfemoral ACURATE neo™ (n=120) prosthesis...
February 7, 2017: EuroIntervention
https://www.readbyqxmd.com/read/28073571/early-clinical-outcomes-of-a-novel-self-expanding-transapical-transcatheter-aortic-valve-bioprosthesis
#11
Michael W A Chu, Rodrigo Bagur, Katie L Losenno, Philip M Jones, Pantelis Diamantouros, Patrick Teefy, Jill J Gelinas, Bob Kiaii
OBJECTIVE: Coronary obstruction remains a challenging complication of transcatheter aortic valve replacement; however, a new self-expanding transapical prosthesis may reduce this risk. The purpose of this study was to evaluate the early 1-year outcomes of patients with low coronary heights who received the Acurate TA bioprosthesis (Symetis, Ecublens, Switzerland). METHODS: Between May 2014 and April 2015, 30 consecutive patients (aged 85 ± 6 years, 63% were female, Society of Thoracic Surgeons score 8...
April 2017: Journal of Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/28029207/prospective-comparison-between-three-tavr-devices-acurate-neo-vs-corevalve-vs-sapien-xt-a-single-heart-team-experience-in-patients-with-severe-aortic-stenosis
#12
Tannas Jatene, Antonio Castro-Filho, Rafael A Meneguz-Moreno, Dimytri A Siqueira, Alexandre A C Abizaid, Auristela I O Ramos, Magaly Arrais, David C S Le Bihan, Rodrigo B M Barretto, Adriana C Moreira, Amanda G M R Sousa, J Eduardo Sousa
OBJECTIVE: We sought to compare the new transcatheter aortic valve replacement (TAVR) device ACURATE neo (ACT) with the already established CoreValve (MCV) and SAPIEN XT (SXT) for the treatment of severe aortic stenosis (AS). BACKGROUND: Very few data on TAVR devices are available beyond MCV and SAPIEN and there is no previous study comparing ACT with MCV and SXT. METHODS: We prospectively evaluated consecutive patients who underwent transfemoral TAVR for the treatment of severe AS...
July 2017: Catheterization and Cardiovascular Interventions
https://www.readbyqxmd.com/read/27872440/successful-percutaneous-implantation-of-symetis-acurate-neo-transcatheter-aortic-bioprosthesis-in-a-patient-with-existing-mechanical-mitral-valve
#13
Sina Ali, Yakup Alsancak, Mustafa Duran, Mehmet Bilge
No abstract text is available yet for this article.
November 2016: Anatolian Journal of Cardiology
https://www.readbyqxmd.com/read/27692823/transcaval-transcatheter-aortic-valve-replacement-with-the-acurate-neo-aortic-bioprosthesis-first-north-american%C3%A2-experience
#14
Rodrigo Bagur, Patrick J Teefy, Bob Kiaii, Aashish Goela, Adam Greenbaum, Michael W A Chu
No abstract text is available yet for this article.
October 24, 2016: JACC. Cardiovascular Interventions
https://www.readbyqxmd.com/read/27677241/first-north-american-experience-with-the-transfemoral-acurate-neo-tm-self-expanding-transcatheter-aortic-bioprosthesis
#15
Rodrigo Bagur, Patrick J Teefy, Bob Kiaii, Pantelis Diamantouros, Michael W A Chu
BACKGROUND: Transcatheter aortic valve implantation (TAVI) has become a therapeutic alternative for patients presenting with severe symptomatic aortic stenosis and considered at high-surgical risk. Paravalvular leak (PVL), conduction disorders, and coronary obstruction remain unresolved procedure-related complications. The aim of this manuscript was to report the first North American experience with the ACURATE-neo(TM) aortic bioprosthesis and its ACURATE-TF(TM) delivery system (Symetis S...
July 2017: Catheterization and Cardiovascular Interventions
https://www.readbyqxmd.com/read/27585056/readmission-to-the-acute-care-unit-and-functional-outcomes-in-patients-with-severe-brain-injury-during-rehabilitation
#16
Domenico Intiso, Andrea Fontana, Giuseppe Maruzzi, Maurizio Tolfa, Massimiliano Copetti, Filomena DI Rienzo
BACKGROUND: Medical and surgical complications are common after brain lesions and may require acute care unit readmission (ACUR) during the rehabilitation stay. This clinical phenomenon has not been explored in subjects with severe brain injury (sBI). AIM: Because sBI patients come from the intensive care unit (ICU), patients may be transferred to rehabilitation before complete clinical stabilization. We investigated ACUR and causes as well as whether those who required ACUR had different functional outcomes...
April 2017: European Journal of Physical and Rehabilitation Medicine
https://www.readbyqxmd.com/read/27502129/-transcatheter-aortic-valve-replacement-the-new-era-new-opportunity-and-new-challenge-of-cardiac-surgery
#17
L Wei, Y Yang, C S Wang, H Liu
Conventional surgical aortic valve replacement is still the current "gold standard" in treatment of aortic valve disease, but part of the high-risk elder patients couldn't tolerate the surgical trauma. Now those people could receive timely and effective treatment with the application of transcatheter aortic valve replacement, and the related guidelines have been published in recent years. With its wide use in recent 10 years, different implantation systems, such as SAPIEN, CoreValve, Lotus, ACURATE neo, have been gradually improved and provened in several large clinical trials...
August 1, 2016: Zhonghua Wai Ke za Zhi [Chinese Journal of Surgery]
https://www.readbyqxmd.com/read/27173866/first-in-man-transfemoral-transcatheter-aortic-valve-implantation-with-the-acurate-neo-for-the-treatment-of-aortic-regurgitation
#18
Stefan Toggweiler, Patric Biaggi, Jürg Grünenfelder, Ivan Reho, Ines Bühler, Roberto Corti
No abstract text is available yet for this article.
May 17, 2016: EuroIntervention
https://www.readbyqxmd.com/read/26888463/improving-outcomes-case-matched-comparison-of-novel-second-generation-versus-first-generation-self-expandable-transcatheter-heart-valves
#19
Andreas Schaefer, Hendrik Treede, Gerhard Schoen, Florian Deuschl, Niklas Schofer, Yvonne Schneeberger, Stefan Blankenberg, Hermann Reichenspurner, Ulrich Schaefer, Lenard Conradi
OBJECTIVES: The published literature has extensively documented clinical benefit derived from transcatheter aortic valve implantation (TAVI) in high-risk patients using self-expanding current-generation transfemoral (TF) transcatheter heart valves (THVs). However, it has also demonstrated apparent shortcomings such as paravalvular leakage (PVL) or need for permanent pacemaker (PM) implantation. We here present a case-matched analysis of acute 30-day outcomes using a novel nitinol-based THV (Symetis Acurate Neo TF™), which may overcome some limitations of currently used devices...
August 2016: European Journal of Cardio-thoracic Surgery
https://www.readbyqxmd.com/read/26762474/successful-percutaneous-implantation-of-symetis-acurate-neo-transcatheter-aortic-bioprosthesis-for-the-treatment-of-pure-aortic-regurgitation
#20
Alfredo Giuseppe Cerillo, Daniel Griese, Sergio Berti
Transcatheter aortic valve implantation (TAVI) was initially developed for the treatment of calcific aortic stenosis. In the recent years, however, TAVI has been used to treat selected patients with pure, severe AR. We report successful transfemoral implantation of a Symetis ACURATE neo bioprosthesis in a severely symptomatic, 87-year-old woman with pure AR and major comorbidities. We decided to use the ACURATE neo bioprosthesis for some of its features appeared to us as potentially useful in the setting of pure AR: the stabilization arches ensure perfect coaxial alignment and extreme stability of the device during deployment, and the "waist" and the skirt were considered useful to obtain a good seal in the absence of significant valvular and annular calcifications...
August 2016: Catheterization and Cardiovascular Interventions
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