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lance adams syndrome

Harsh V Gupta, John N Caviness
BACKGROUND: Myoclonus may occur after hypoxia. In 1963, Lance and Adams described persistent myoclonus with other features after hypoxia. However, myoclonus occurring immediately after hypoxia may demonstrate different syndromic features from classic Lance-Adams syndrome (LAS). The aim of this review is to provide up-to-date information about the spectrum of myoclonus occurring after hypoxia with emphasis on neurophysiological features. METHODS: A literature search was performed on PubMed database from 1960 to 2015...
2016: Tremor and Other Hyperkinetic Movements
Gaurav Bhaskar Nigam, Sachin Suresh Babu, C Sudhir Peter, C Shobhna Peter
Predicting the neurological outcome in survivors of cardiorespiratory arrest is difficult. A distinction has been made between acute and chronic posthypoxic myoclonus, called myoclonic status epilepticus and Lance-Adams syndrome (LAS), respectively, with the acute condition carrying a bad prognosis. Here, we report a case of a 37-year-old female who developed seizures after a successful cardiopulmonary resuscitation. The available literature on such cases is very rare and has generally mentioned a poor outcome...
September 2016: Indian Journal of Critical Care Medicine
Vivek Rayadurg, Radhakrishnan Muthuchellappan, Umamaheshwara Rao
Posthypoxic myoclonus (Lance-Adams syndrome) is characterized by myoclonus involving multiple muscle groups which is resistant to most conventional antiepileptic drugs. We present a case of hypoxic brain injury-induced myoclonic status epilepticus successfully controlled with isoflurane. The antimyoclonic effects of isoflurane are likely due to potentiation of inhibitory postsynaptic GABAA receptor-mediated currents and its effects on thalamocortical pathways. It is effective even when intravenous agents fail to control myoclonus...
August 2016: Indian Journal of Critical Care Medicine
Adam L Ware, Dylan V Miller, Lance K Erickson, Shaji C Menon
BACKGROUND: Marfan syndrome (MFS) is a multisystem connective tissue disorder that can lead to aortic dilation requiring aortic root replacement. Neonatal MFS (nMFS) is a rare and severe form of MFS compared to classic MFS (cMFS). Aortic root histology in MFS is thought to demonstrate predominantly medial degeneration (MD) of a translamellar mucoid extracellular matrix accumulation (MEMA-T) vs. the intralamellar mucoid extracellular matrix accumulation (MEMA-I) seen in other aortopathies...
September 2016: Cardiovascular Pathology: the Official Journal of the Society for Cardiovascular Pathology
Bernhard J Steinhoff, Matthias Bacher, Christoph Kurth, Anke M Staack, Reinhold Kornmeier
Perampanel (PER) is the first-in-class selective, noncompetitive α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptor antagonist that has been licensed and marketed as antiepileptic drug (AED) indicated for patients with partial-onset and primary generalized tonic-clonic seizures. A positive effect was reported in some patients with epileptic myoclonic jerks in idiopathic generalized epilepsy and in progressive myoclonic epilepsy. We treated a male patient with posthypoxic nonepileptic myoclonus (Lance-Adams syndrome) with add-on PER and achieved an almost complete cessation of jerks...
2016: Epilepsy & Behavior Case Reports
Brin Freund, Raoul Sutter, Peter Kaplan
Acute posthypoxic myoclonus portends a poor prognosis. Another form of posthypoxic myoclonus, Lance-Adams syndrome, is associated with a better outcome. Differentiating these two entities is important in prognostication and guiding further medical intervention. This can be difficult in the acute setting after hypoxic brain injury but the use of neurophysiologic studies may be helpful. In this article, we present a case of a patient who presented after pulseless electrical activity arrest, underwent targeted temperature management and subsequently developed Lance-Adams syndrome...
April 25, 2016: Clinical EEG and Neuroscience: Official Journal of the EEG and Clinical Neuroscience Society (ENCS)
Kang Min Park, Yong Hee Han, Tae Hyung Kim, Chi Woong Mun, Kyong Jin Shin, Sam Yeol Ha, JinSe Park, Sung Eun Kim
No abstract text is available yet for this article.
December 2015: Clinical Neurology and Neurosurgery
Giuseppe D Sanna, Antonio Demurtas, Stefano Cossa, Francesca Murgia, Paola Murgia, Annamaria Ara
No abstract text is available yet for this article.
February 2016: American Journal of Emergency Medicine
Takashi Asahi, Daina Kashiwazaki, Nobuhiro Dougu, Genko Oyama, Shutaro Takashima, Kortaro Tanaka, Satoshi Kuroda
No abstract text is available yet for this article.
June 2015: Journal of Neurology
Julio T Chong, MaryEllen T Dolat, Adam P Klausner, Ema Dragoescu, Lance J Hampton
INTRODUCTION: Few studies have adequately addressed the indications, efficacy, and quality-of-life for cystectomy performed for non-malignant bladder conditions. Patients with debilitating non-malignant bladder conditions who have failed all previous conservative therapies may undergo various forms of cystectomy, including partial, simple or radical cystectomy. We provide a review of the current literature and recommendations for cystectomy for various non-malignant bladder conditions...
October 2014: Canadian Journal of Urology
Helena Laciuga, John C Rosenbek, Paul W Davenport, Christine M Sapienza
This review presents the available evidence for the effects of expiratory muscle strength training (EMST) with the use of a pressure threshold device. The investigators used computerized database searches for studies reporting the outcomes of pressure threshold EMST published after 1994. A total of 24 selected articles presented outcomes related but not limited to respiratory function, such as speech, swallow, voice, and cough function in persons with neurologic conditions such as Parkinson disease, multiple sclerosis, and Lance-Adams syndrome; in persons with respiratory diseases, such as chronic obstructive pulmonary disease; and in healthy young adults and sedentary and active elderly...
2014: Journal of Rehabilitation Research and Development
Faik Ilik, Mustafa Kemal Ilik, Ilker Cöven
Chronic post-hypoxic myoclonus, also known as Lance-Adams syndrome (LAS) is a neurological complication characterized by uncontrolled myoclonic jerks following cardiac arrest. In this article, clinical manifestation and symptomatic treatment options are discussed especially concerning the rationale of use of levatiracetam in patients with Lance-Adams syndrome. Clinical presentation is action myoclonus associated with cerebellar ataxia, postural imbalance, and very mild intellectual deficit. An 18-year-old female patient was admitted to our intensive care unit in a coma...
2014: Iranian Journal of Child Neurology
Jennifer Accardo, Domenico De Lisi, Paola Lazzerini, Alberto Primavera
In anoxic coma, myoclonic status epilepticus and other nonreactive epileptiform patterns are considered as signs of poor prognosis. We report the case of a good recovery in a prolonged comatose myoclonic status epilepticus (MSE) after a cardiac arrest (CA) treated with mild therapeutic hypothermia (TH) in a patient who had undergone a bone marrow transplantation for Hodgkin's lymphoma. This case emphasizes the opportunity of performing an electroencephalogram (EEG) in the acute period after an hypoxic-ischemic insult and underlines the diagnostic difficulties between MSE and Lance-Adams syndrome, which classically occurs after the patient has regained consciousness, but can also begin while the patient is still comatose or sedated...
2013: Case Reports in Neurological Medicine
Tjerk Lagrand, Ania Winogrodzka
A 66-year-old man had a history of an anterior myocardial infarction followed by a successful cardiopulmonary resuscitation and a posthypoxic myoclonus, also known as Lance-Adams syndrome (LAS). Eight years ago, he was admitted to the emergency department with the same myoclonic jerks during an intercurrent respiratory infection. After treatment with clonazepam and resolution of the infection, the myoclonus promptly disappeared. This case report suggests that relapses of successfully treated LAS can occur in vulnerable patients, as it's a chronic form of myoclonus...
November 29, 2013: BMJ Case Reports
Ah-Reum Cho, Jae-Young Kwon, Joo-Yun Kim, Eun-Soo Kim, Hee-Young Kim
Myoclonic status epilepticus (MSE) within the first 24 hours after cardiopulmonary resuscitation (CPR) predicts poor prognosis, enough to discontinue the treatment. In contrast, chronic MSE appearing a few days after CPR is called Lance-Adams syndrome (LAS), which is characterized by preserved intellect and a favorable prognosis. We herein report a case of LAS, which developed after a transient hypoxic event without an overt cardiac arrest due to hematoma formation in the neck after partial glossectomy. Differential diagnosis was also challenging as LAS was developed 8 hours after the hypoxic event...
October 2013: Korean Journal of Anesthesiology
H Yamaoka, N Tomemori, K Hayama
No abstract text is available yet for this article.
September 1994: Journal of Anesthesia
Jun-Hwa Shin, Jong Moon Park, A Ram Kim, Hee Suk Shin, Eun Shin Lee, Min-Kyun Oh, Chul Ho Yoon
It is not common for a patient who survives cardiac arrest to experience significant neurologic impairment such as acute and chronic post-hypoxic myoclonus, known as Lance-Adams syndrome. This syndrome is predominantly characterized by myoclonus that starts days to weeks after cardiopulmonary resuscitation in patients who regained consciousness. Although several cases of LAS were reported, the decisive treatment method has not been established. We report a 43 year old man with Lance-Adams syndrome who showed long-term improvement through treatment with anti-myoclonic agents and participation in a rehabilitation program...
August 2012: Annals of Rehabilitation Medicine
Yi Li, Xiao-su Yang, Bo Xiao, Huan Yang, Jian-an He, Lan Xiao, Yi Shu, Xue-ying Long, Wei-hua Liao
OBJECTIVE: To explore the clinical and imaging features of anoxic-ischemic encephalopathy (AIE) patients after cardiopulmonary resuscitation. METHODS: A total of 28 qualified AIE patients during the last decade from Xiangya Hospital, Central South University were recruited and analyzed retrospectively. RESULTS: The symptoms of status epilepticus, acute posthypoxic myoclonus, Lance-Adams syndrome, subarachnoid hemorrhage and cognitive deficits were observed...
June 19, 2012: Zhonghua Yi Xue za Zhi [Chinese medical journal]
Ha Lim Lee, Ju Kang Lee
Lance-Adams syndrome (LAS) is a rare complication of successful cardiopulmonary resuscitation and is often accompanied by action myoclonus. LAS is seen in patients who have undergone a cardiorespiratory arrest, later regained consciousness, and then developed myoclonus days or weeks after the event. Less than 150 cases of LAS have been reported in the worldwide medical literature. Here, we present a 32-year-old man who suffered from myoclonus after hypoxic brain damage due to hanging himself. This case was diagnosed as Lance-Adams syndrome according to a history of hypoxic brain damage, the clinical features, and the neuroimages such as brain SPECT...
December 2011: Annals of Rehabilitation Medicine
Arvind Rajamani, Ian Seppelt, Joan Bourne
Neurological prognostication in cardiac arrest survivors is difficult, especially when the primary etiology is respiratory arrest. Prognostic factors designed to have zero false-positive rates to robustly confirm poor outcome are usually inadequate to rule out poor outcomes (i.e., high specificity and low sensitivity). One of the least understood prognosticators is generalised status myoclonus (GSM), with case reports confusing GSM, isolated myoclonic jerks and post-hypoxic intention myoclonus (Lance Adams syndrome [LAS])...
April 2011: Indian Journal of Critical Care Medicine
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