keyword
MENU ▼
Read by QxMD icon Read
search

Estrogen microbiome

keyword
https://www.readbyqxmd.com/read/29121700/difference-in-the-gut-microbiome-between-ovariectomy-induced-obesity-and-diet-induced-obesity
#1
Sungmi Choi, Yu-Jin Hwang, Min-Jeong Shin, Hana Yi
During menopausal transition, the imbalance of estrogen causes body weight gain. Although gut microbiome dysbiosis has been reported in postmenopausal obesity, it is not clear whether there is any difference in the microbiome profile between dietary-induced obesity and postmenopausal obesity. Therefore, in this study, we analyzed intestinal samples from ovariectomized mice and compared them to those of mice with high fat diet-induced obesity. To further evaluate the presence of menopause-specific bacteria-gene interactions, we also analyzed the liver transcriptome...
November 9, 2017: Journal of Microbiology and Biotechnology
https://www.readbyqxmd.com/read/29100781/estrogens-and-female-liver-health
#2
Karen L Chen, Zeynep Madak-Erdogan
Due to declining estrogen levels during menopause, NAFLD prevalence is higher in postmenopausal women compared to in premenopausal women or in men. Postmenopausal women are more susceptible to weight gain, fat redistribution and dyslipidemia, all major hallmarks of metabolic syndrome associated with increased NAFLD risk. Gut microbiota plays important roles in development of gastrointestinal tract, metabolism and immunity. Host-microbe interactions allows regulation of a wide range of pathways that affect healthy and diseased physiology...
November 1, 2017: Steroids
https://www.readbyqxmd.com/read/28893284/role-of-sex-hormones-and-the-vaginal-microbiome-in-susceptibility-and-mucosal-immunity-to-hiv-1-in-the-female-genital-tract
#3
REVIEW
Danielle Vitali, Jocelyn M Wessels, Charu Kaushic
While the prevalence of Human immunodeficiency virus-1 (HIV-1) infection has stabilized globally, it continues to be the leading cause of death among women of reproductive age. The majority of new infections are transmitted heterosexually, and women have consistently been found to be more susceptible to HIV-1 infection during heterosexual intercourse compared to men. This emphasizes the need for a deeper understanding of how the microenvironment in the female genital tract (FGT) could influence HIV-1 acquisition...
September 12, 2017: AIDS Research and Therapy
https://www.readbyqxmd.com/read/28386898/estrogen-receptor-beta-mediates-hepatotoxicity-induced-by-perfluorooctane-sulfonate-in-mouse
#4
Cheng Xu, Zhao-Yan Jiang, Qian Liu, Hui Liu, Aihua Gu
Perfluorooctane sulfonate (PFOS), an artificial fluorosurfactant and global contaminant, is used widely in various consumer products. In this study, we investigated the function of estrogen receptor β (ERβ) in PFOS-induced bile acid and cholesterol metabolism disorders and gut microbiome using ERβ knockout mice that were exposed to PFOS by gavage. Our results showed that a daily dose of 5 mg PFOS/kg significantly induced hydropic degeneration and vacuolation in hepatic cells, reduced bile acid, and cholesterol levels in liver tissue, and influenced the abundance and composition of gut microbiota...
May 2017: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/28008325/lactobacilli-dominance-and-vaginal-ph-why-is-the-human-vaginal-microbiome-unique
#5
Elizabeth A Miller, DeAnna E Beasley, Robert R Dunn, Elizabeth A Archie
The human vaginal microbiome is dominated by bacteria from the genus Lactobacillus, which create an acidic environment thought to protect women against sexually transmitted pathogens and opportunistic infections. Strikingly, lactobacilli dominance appears to be unique to humans; while the relative abundance of lactobacilli in the human vagina is typically >70%, in other mammals lactobacilli rarely comprise more than 1% of vaginal microbiota. Several hypotheses have been proposed to explain humans' unique vaginal microbiota, including humans' distinct reproductive physiology, high risk of STDs, and high risk of microbial complications linked to pregnancy and birth...
2016: Frontiers in Microbiology
https://www.readbyqxmd.com/read/27897166/erratum-effects-of-low-dose-estrogen-therapy-on-the-vaginal-microbiomes-of-women-with-atrophic-vaginitis
#6
Jian Shen, Ning Song, Christopher J Williams, Celeste J Brown, Zheng Yan, Chen Xu, Larry J Forney
No abstract text is available yet for this article.
November 29, 2016: Scientific Reports
https://www.readbyqxmd.com/read/27709424/gastrointestinal-microbiome-and-breast-cancer-correlations-mechanisms-and-potential-clinical-implications
#7
REVIEW
Jiqiao Yang, Qiuwen Tan, Qingyu Fu, Yaojie Zhou, Yuanyuan Hu, Shenli Tang, Yuting Zhou, Junhui Zhang, Juanjuan Qiu, Qing Lv
Gastrointestinal microbiome plays as a symbiont which provides protection effect against invading pathogens, aids in the immune system development, nutrient reclamation and absorption as well as molecule breakdown. And it may avert carcinogenesis through these biological activities. By now, studies have been carried out to elaborate the association between gastrointestinal microbiome and breast cancer. It has been implicated that breast cancer was substantially associated with estrogen-dependent and estrogen-independent functions of gastrointestinal microbiome...
March 2017: Breast Cancer: the Journal of the Japanese Breast Cancer Society
https://www.readbyqxmd.com/read/27698617/unraveling-the-dynamics-of-the-human-vaginal-microbiome
#8
REVIEW
Kenetta L Nunn, Larry J Forney
Four Lactobacillus species, namely L. crispatus , L. iners, L. gasseri, and L. jensenii, commonly dominate the vaginal communities of most reproductive-age women. It is unclear why these particular species, and not others, are so prevalent. Historically, estrogen-induced glycogen production by the vaginal epithelium has been proffered as being key to supporting the proliferation of vaginal lactobacilli. However, the 'fly in the ointment' (that has been largely ignored) is that the species of Lactobacillus commonly found in the human vagina cannot directly metabolize glycogen...
September 2016: Yale Journal of Biology and Medicine
https://www.readbyqxmd.com/read/27451320/menopause-and-the-vaginal-microbiome
#9
REVIEW
Alicia L Muhleisen, Melissa M Herbst-Kralovetz
For over a century it has been well documented that bacteria in the vagina maintain vaginal homeostasis, and that an imbalance or dysbiosis may be associated with poor reproductive and gynecologic health outcomes. Vaginal microbiota are of particular significance to postmenopausal women and may have a profound effect on vulvovaginal atrophy, vaginal dryness, sexual health and overall quality of life. As molecular-based techniques have evolved, our understanding of the diversity and complexity of this bacterial community has expanded...
September 2016: Maturitas
https://www.readbyqxmd.com/read/27125180/corrigendum-discovery-of-a-novel-seminal-fluid-microbiome-and-influence-of-estrogen-receptor-alpha-genetic-status
#10
Angela B Javurek, William G Spollen, Amber M Mann Ali, Sarah A Johnson, Dennis B Lubahn, Nathan J Bivens, Karen H Bromert, Mark R Ellersieck, Scott A Givan, Cheryl S Rosenfeld
No abstract text is available yet for this article.
April 29, 2016: Scientific Reports
https://www.readbyqxmd.com/read/27107051/the-intestinal-microbiome-and-estrogen-receptor-positive-female-breast-cancer
#11
REVIEW
Maryann Kwa, Claudia S Plottel, Martin J Blaser, Sylvia Adams
The huge communities of residential microbes, including bacteria, viruses, Archaea, and Eukaryotes, that colonize humans are increasingly recognized as playing important roles in health and disease. A complex populous ecosystem, the human gastrointestinal (GI) tract harbors up to 10(11) bacterial cells per gram of luminal content, whose collective genome, the gut metagenome, contains a vastly greater number of individual genes than the human genome. In health, the function of the microbiome might be considered to be in dynamic equilibrium with the host, exerting both local and distant effects...
August 2016: Journal of the National Cancer Institute
https://www.readbyqxmd.com/read/27103314/effects-of-low-dose-estrogen-therapy-on-the-vaginal-microbiomes-of-women-with-atrophic-vaginitis
#12
Jian Shen, Ning Song, Christopher J Williams, Celeste J Brown, Zheng Yan, Chen Xu, Larry J Forney
Atrophic vaginitis (AV) is common in postmenopausal women, but its causes are not well understood. The symptoms, which include vaginal itching, burning, dryness, irritation, and dyspareunia, can usually be alleviated by low doses of estrogen given orally or locally. Regrettably, the composition of vaginal bacterial communities in women with AV have not been fully characterized and little is known as to how these communities change over time in response to hormonal therapy. In the present intervention study we determined the response of vaginal bacterial communities in postmenopausal women with AV to low-dose estrogen therapy...
April 22, 2016: Scientific Reports
https://www.readbyqxmd.com/read/26971397/discovery-of-a-novel-seminal-fluid-microbiome-and-influence-of-estrogen-receptor-alpha-genetic-status
#13
Angela B Javurek, William G Spollen, Amber M Mann Ali, Sarah A Johnson, Dennis B Lubahn, Nathan J Bivens, Karen H Bromert, Mark R Ellersieck, Scott A Givan, Cheryl S Rosenfeld
Bacteria harbored in the male reproductive system may influence reproductive function and health of the male and result in developmental origins of adult health and disease (DOHaD) effects in his offspring. Such effects could be due to the seminal fluid, which is slightly basic and enriched with carbohydrates; thereby, creating an ideal habitat for microbes or a potential seminal fluid microbiome (SFM). Using wild-type (WT) and estrogen receptor-alpha (ESR1) knockout (KO) male mice, we describe a unique SFM whose inhabitants differ from gut microbes...
March 14, 2016: Scientific Reports
https://www.readbyqxmd.com/read/26658991/risk-of-inflammatory-bowel-disease-with-oral-contraceptives-and-menopausal-hormone-therapy-current-evidence-and-future-directions
#14
REVIEW
Hamed Khalili
Crohn's disease (CD) and ulcerative colitis (UC), collectively known as inflammatory bowel diseases, are archetypical inflammatory disorders of the gastrointestinal tract with rising incidence worldwide. Although the role of genetic factors in disease development has been highlighted by genome-wide association studies, environmental risk factors likely play a pivotal role in development of CD and UC. Prior observational studies have suggested a link between exogenous hormone use and risk of CD and UC. Specifically, studies have shown an association between oral contraceptive use and risk of CD and menopausal hormone therapy and risk of UC...
March 2016: Drug Safety: An International Journal of Medical Toxicology and Drug Experience
https://www.readbyqxmd.com/read/26265751/ovariectomy-results-in-differential-shifts-in-gut-microbiota-in-low-versus-high-aerobic-capacity-rats
#15
Kimberly A Cox-York, Amy M Sheflin, Michelle T Foster, Christopher L Gentile, Amber Kahl, Lauren G Koch, Steven L Britton, Tiffany L Weir
The increased risk for cardiometabolic disease with the onset of menopause is widely studied and likely precipitated by the decline in endogenous estradiol (E2), yet the precise mechanisms are unknown. The gut microbiome is involved in estrogen metabolism and has been linked to metabolic disease, suggesting its potential involvement in the postmenopausal phenotype. Furthermore, menopause-associated risk factors, as well as gut ecology, are altered with exercise. Therefore, we studied microbial changes in an ovariectomized (OVX vs...
August 2015: Physiological Reports
https://www.readbyqxmd.com/read/25211668/associations-of-the-fecal-microbiome-with-urinary-estrogens-and-estrogen-metabolites-in-postmenopausal-women
#16
Barbara J Fuhrman, Heather Spencer Feigelson, Roberto Flores, Mitchell H Gail, Xia Xu, Jacques Ravel, James J Goedert
CONTEXT: The gut microbiota may influence the risk of breast cancer through effects on endogenous estrogens. OBJECTIVE: The objective of the study was to investigate whether urinary estrogens and estrogen metabolites are associated with the diversity and composition of the fecal microbiome. DESIGN AND SETTING: This was a cross-sectional study among women enrolled in Kaiser Permanente of Colorado. PARTICIPANTS: A total of 60 women drawn from a random sample of healthy postmenopausal women (aged 55-69 y), without current or recent use of antibiotics or hormone therapy and no history of cancer or gastrointestinal disease participated in the study...
December 2014: Journal of Clinical Endocrinology and Metabolism
https://www.readbyqxmd.com/read/24390919/potential-influence-of-the-microbiome-on-infertility-and-assisted-reproductive-technology
#17
REVIEW
Ido Sirota, Shvetha M Zarek, James H Segars
Although an altered vaginal microbiota has been demonstrated to affect parturition, its role in assisted reproductive technologies is uncertain. Nevertheless, the effect of known pathogens such as Mycoplasma tuberculosis, Chlamydia trachomatis, and Neisseria gonorrhoeae is clear, causing subclinical changes thought to be risk factors in subfertility. The Human Microbiome Project (HMP) has allowed for metagenomic studies to aid in characterizing normal vaginal flora. Recent findings from the HMP demonstrate that many different species of Lactobacillus are present in the vaginal tract, with a few that predominate...
January 2014: Seminars in Reproductive Medicine
https://www.readbyqxmd.com/read/24187630/evolving-concepts-how-diet-and-the-intestinal-microbiome-act-as-modulators-of-breast-malignancy
#18
REVIEW
Iuliana Shapira, Keith Sultan, Annette Lee, Emanuela Taioli
The intestinal microbiome plays an important role in human physiology. Next-generation sequencing technologies, knockout and gnotobiotic mouse models, fecal transplant data and epidemiologic studies have accelerated our understanding of microbiome abnormalities seen in immune diseases and malignancies. Dysbiosis is the disturbed microbiome ecology secondary to external pressures such as host diseases, medications, diet and genetic conditions often leading to abnormalities of the host immune system. Specifically dysbiosis has been shown to lower circulating lymphocytes, and increase neutrophil to lymphocyte ratio, a finding which has been associated with a decreased survival in women with breast cancers...
2013: ISRN Oncology
https://www.readbyqxmd.com/read/24166771/the-primate-vaginal-microbiome-comparative-context-and-implications-for-human-health-and-disease
#19
REVIEW
Rebecca M Stumpf, Brenda A Wilson, Angel Rivera, Suleyman Yildirim, Carl J Yeoman, John D Polk, Bryan A White, Steven R Leigh
The primate body hosts trillions of microbes. Interactions between primate hosts and these microbes profoundly affect primate physiology, reproduction, health, survival, and ultimately, evolution. It is increasingly clear that primate health cannot be understood fully without knowledge of host-microbial interactions. Our goals here are to review what is known about microbiomes of the female reproductive tract and to explore several factors that influence variation within individuals, as well as within and between primate species...
December 2013: American Journal of Physical Anthropology
https://www.readbyqxmd.com/read/23985562/management-of-symptomatic-vulvovaginal-atrophy-2013-position-statement-of-the-north-american-menopause-society
#20
(no author information available yet)
OBJECTIVE: To update and expand the previous position statement of The North American Menopause Society (NAMS) on the management of symptomatic vulvovaginal atrophy (VVA) in postmenopausal women. METHODS: NAMS searched PubMed for medical literature on VVA published since their 2007 position statement on the role of local vaginal estrogen for treatment of vaginal atrophy in postmenopausal women. A panel of acknowledged experts in the field of genitourinary health reviewed the literature to evaluate new evidence on local estrogen as well as on other management options available or in development for symptomatic VVA...
September 2013: Menopause: the Journal of the North American Menopause Society
keyword
keyword
49655
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"