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Hypothyroid diet

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https://www.readbyqxmd.com/read/27852654/cobalt-cardiomyopathy-a-critical-reappraisal-in-light-of-a-recent-resurgence
#1
Milton Packer
Cobalt can cause a distinctive, rapidly progressive and reversible depression of cardiac systolic function, which is readily distinguished from other causes of cardiomyopathy. Patients present with the subacute onset of severe heart failure, which is accompanied by hypotension and cyanosis, pericardial effusion, low voltage on the electrocardiogram, marked elevation of serum enzymes, and lactic acidosis. They typically have a history of lethargy, anorexia, and weight loss in the months preceding the illness and exhibit other evidence of cobalt's effects on the body (eg, polycythemia and goiter)...
December 2016: Circulation. Heart Failure
https://www.readbyqxmd.com/read/27837466/thyroid-disruption-by-perfluorooctane-sulfonate-pfos-and-perfluorooctanoate-pfoa
#2
REVIEW
F Coperchini, O Awwad, M Rotondi, F Santini, M Imbriani, L Chiovato
BACKGROUND: Perfluorooctane sulfonate (PFOS) and perfluorooctanoate (PFOA) are two fluorinated compounds widely used in industry because of their useful chemical characteristics. They were identified as endocrine disruptors due to their ability to interfere with thyroid function. The resistance of PFOA and PFOS to environmental degradation, their bio-accumulation in food chains, and their long half-life raised concern in the scientific community, and several studies were performed with the aim to establish the real dangerousness of these compounds for the human health...
November 11, 2016: Journal of Endocrinological Investigation
https://www.readbyqxmd.com/read/27829582/postprandial-hyperlipidemia-and-remnant-lipoproteins
#3
Daisaku Masuda, Shizuya Yamashita
Fasting hypertriglyceridemia is positively associated with the morbidity of coronary heart disease (CHD), and postprandial (non-fasting) hypertriglyceridemia is also correlated with the risk status for CHD, which is related to the increase in chylomicron (CM) remnant lipoproteins produced from the intestine. CM remnant particles, as well as oxidized low density lipoprotein (LDL) or very low density lipoprotein (VLDL) remnants, are highly atherogenic and act by enhancing systemic inflammation, platelet activation, coagulation, thrombus formation, and macrophage foam cell formation...
November 8, 2016: Journal of Atherosclerosis and Thrombosis
https://www.readbyqxmd.com/read/27824612/effects-of-altered-thyroid-states-on-oxidative-stress-parameters-in-rats
#4
Sehkar Oktay, Lebriz Uslu, Nesrin Emekli
BACKGROUND: Thyroid hormones are effective on oxidant-antioxidant balance by leading basal metabolic rate. In this study, the effects of altered thyroid states on low density lipoprotein (LDL) oxidation and oxidative stress parameters were investigated in an experimental animal model. METHODS: Thirty female Wistar Albino rats were equally divided into 3 groups as follows: control group; hypothyroid group (methimazole (75 mg/100 g was added to diet); hyperthyroid group [L-thyroxine (0...
November 8, 2016: Journal of Basic and Clinical Physiology and Pharmacology
https://www.readbyqxmd.com/read/27784959/endocrine-manifestations-in-celiac-disease
#5
REVIEW
Hugh James Freeman
Celiac disease (CD) is an autoimmune small intestinal mucosal disorder that often presents with diarrhea, malabsorption and weight loss. Often, one or more associated endocrine disorders may be associated with CD. For this review, methods involved an extensive review of published English-language materials. In children and adolescents, prospective studies have demonstrated a significant relationship to insulin-dependent or type 1 diabetes, whereas in adults, autoimmune forms of thyroid disease, particularly hypothyroidism, may commonly co-exist...
October 14, 2016: World Journal of Gastroenterology: WJG
https://www.readbyqxmd.com/read/27695051/standardization-of-a-physiologic-hypoparathyroidism-animal-model
#6
Soo Yeon Jung, Ha Yeong Kim, Hae Sang Park, Xiang Yun Yin, Sung Min Chung, Han Su Kim
Ideal hypoparathyroidism animal models are a prerequisite to developing new treatment modalities for this disorder. The purpose of this study was to evaluate the feasibility of a model whereby rats were parathyroidectomized (PTX) using a fluorescent-identification method and the ideal calcium content of the diet was determined. Thirty male rats were divided into surgical sham (SHAM, n = 5) and PTX plus 0, 0.5, and 2% calcium diet groups (PTX-FC (n = 5), PTX-NC (n = 10), and PTX-HC (n = 10), respectively). Serum parathyroid hormone levels decreased to non-detectable levels in all PTX groups...
2016: PloS One
https://www.readbyqxmd.com/read/27499687/low-carbohydrate-diet-based-intervention-for-obstructive-sleep-apnea-and-primary-hypothyroidism-in-an-obese-japanese-man
#7
Yoshio Tokuchi, Yayoi Nakamura, Yusuke Munekata, Fumio Tokuchi
BACKGROUND: Obesity is a major risk factor for obstructive sleep apnea (OSA), and weight loss is necessary in the overall management of obese patients with OSA. However, primary care physicians can provide only limited weight loss with lifestyle interventions, usually reducing a patient's body weight by only 2.5 kg or less after 6-18 months. CASE PRESENTATION: A 45-year-old Japanese man was referred to our clinic owing to obesity, daytime sleepiness, and snoring during sleep...
2016: Asia Pacific Family Medicine
https://www.readbyqxmd.com/read/27381728/thyroid-dysfunction-either-hyper-or-hypothyroidism-promotes-gallstone-formation-by-different-mechanisms
#8
Yong Wang, Xing Yu, Qun-Zi Zhao, Shu Zheng, Wen-Jie Qing, Chun-di Miao, Jaiswal Sanjay
We have investigated comprehensively the effects of thyroid function on gallstone formation in a mouse model. Gonadectomized gallstone-susceptible male C57BL/6 mice were randomly distributed into three groups each of which received an intervention to induce hyperthyroidism, hypothyroidism, or euthyroidism. After 5 weeks of feeding a lithogenic diet of 15% (w/w) butter fat, 1% (w/w) cholesterol, and 0.5% (w/w) cholic acid, mice were killed for further experiments. The incidence of cholesterol monohydrate crystal formation was 100% in mice with hyperthyroidism, 83% in hypothyroidism, and 33% in euthyroidism, the differences being statistically significant...
July 2016: Journal of Zhejiang University. Science. B
https://www.readbyqxmd.com/read/27366039/is-pancreatic-exocrine-insufficiency-in-celiac-disease-related-to-structural-alterations-in-pancreatic-parenchyma
#9
Surinder S Rana, Arvind Dambalkar, Puneet Chhabra, Ravi Sharma, Ritambhra Nada, Vishal Sharma, Satyavati Rana, Deepak K Bhasin
BACKGROUND: Although exocrine pancreatic insufficiency (EPI) has been reported in a number of patients with celiac disease (CD), it is not clear if this is primarily a functional or a structural defect. We studied pancreatic structural abnormalities by endoscopic ultrasound (EUS) in adult CD patients with EPI. METHODS: Pancreatic exocrine function was prospectively assessed in 36 recently diagnosed CD patients (mean age: 29.8 years) by measuring fecal elastase. Pancreatic structural changes were assessed in CD patients with EPI by EUS and elastography...
July 2016: Annals of Gastroenterology: Quarterly Publication of the Hellenic Society of Gastroenterology
https://www.readbyqxmd.com/read/27353948/development-and-validation-of-pediatric-endocrine-knowledge-assessment-questionnaire-pekaq-impact-of-pekaq-intervention-study
#10
Nidhi Gupta, Marwan Zidan, Kathleen Moltz, Amita Adhikari, Colleen Buggs-Saxton, Hanaa Zidan, Dania Abushanab, Aida Lteif, Chandra Edwin
OBJECTIVE: While there is a general agreement that patient education is essential for compliance, no objective tools exist to assess knowledge of children and parents of children with endocrine disorders. We aimed to design and validate a Pediatric Endocrine Knowledge Assessment Questionnaire (PEKAQ) for congenital hypothyroidism, Hashimoto's thyroiditis, isolated growth hormone deficiency, Graves' disease and congenital adrenal hyperplasia. We evaluated baseline knowledge of children and parents of children with these disorders and assessed impact of educational intervention...
June 29, 2016: Journal of Clinical Research in Pediatric Endocrinology
https://www.readbyqxmd.com/read/27289509/the-effectiveness-of-the-low-energy-diet-in-overweight-and-obese-adults
#11
COMPARATIVE STUDY
Beata Całyniuk, Elżbieta Grochowska-Niedworok, Małgorzata Muc-Wierzgoń, Ewa Nowakowska-Zajdel, Marcin Osowski
BACKGROUND: Excess body weight is one of the most common health and economic problems of the contemporary world. According to the assessments of the World Health Organization (WHO), almost billion adults are overweight and at least 300 million were diagnosed with clinical obesity. Health consequences of overweight are: ischemic heart disease, congestive cardiac failure, hypertension, arteriosclerotic vascular disease, diabetes mellitus type 2, tumours, degenerative joint disease and many more...
2016: Roczniki Państwowego Zakładu Higieny
https://www.readbyqxmd.com/read/27244854/iodine-deficiency-and-hypothyroidism-from-voluntary-diet-restrictions-in-the-us-case-reports
#12
Stephanie Booms, Elizabeth Hill, Leah Kulhanek, Jennifer Vredeveld, Brigid Gregg
Iodine deficiency is rare in the United States today, and this is largely due to the effectiveness of iodization in the general food supply. Recent trends among specific populations of children in the United States include adopting food restrictions, such casein-free and gluten-free diets. Although the effect of these types of diets on overall nutrition status and certain micronutrients has been studied in children with autism spectrum disorder, the effect of these limitations on iodine levels in children has not been assessed...
June 2016: Pediatrics
https://www.readbyqxmd.com/read/27132724/coeliac-disease-in-patients-with-short-stature-a-tertiary-care-centre-experience
#13
Prashant Singh, Piyush Kumar Sharma, Abhishek Agnihotri, Viveka P Jyotsna, Prasenjit Das, Siddhartha Datta Gupta, Govind K Makharia, Rajesh Khadgawat
BACKGROUND: We aimed to determine the prevalence of coeliac disease among children with short stature at a tertiary care centre and to define the predictors for coeliac disease, if any, in them. METHODS: In this retrospective study, we reviewed the case records of children and adolescents with growth retardation attending the Paediatric Endocrinology Clinic from January 2008 to June 2011. All patients underwent the multi-tier stratified diagnostic protocol for complete evaluation of short stature...
July 2015: National Medical Journal of India
https://www.readbyqxmd.com/read/27033232/developmental-hypothyroxinemia-and-hypothyroidism-reduce-parallel-fiber-purkinje-cell-synapses-in-rat-offspring-by-downregulation-of-neurexin1-cbln1-glud2-tripartite-complex
#14
Yuan Wang, Jing Dong, Yi Wang, Wei Wei, Binbin Song, Zhongyan Shan, Weiping Teng, Jie Chen
Iodine is a significant micronutrient. Iodine deficiency (ID)-induced hypothyroxinemia and hypothyroidism during developmental period can cause cerebellar dysfunction. However, mechanisms are still unclear. Therefore, the present research aims to study effects of developmental hypothyroxinemia caused by mild ID and hypothyroidism caused by severe ID or methimazole (MMZ) on parallel fiber-Purkinje cell (PF-PC) synapses in filial cerebellum. Maternal hypothyroxinemia and hypothyroidism models were established in Wistar rats using ID diet and deionized water supplemented with different concentrations of potassium iodide or MMZ water...
October 2016: Biological Trace Element Research
https://www.readbyqxmd.com/read/26962119/dietary-induced-chronic-hypothyroidism-negatively-affects-rat-follicular-development-and-ovulation-rate-and-is-associated-with-oxidative-stress
#15
Li Meng, Eddy Rijntjes, Hans Swarts, Annelies Bunschoten, Inge van der Stelt, Jaap Keijer, Katja Teerds
The long-term effects of chronic hypothyroidism on ovarian follicular development in adulthood are not well known. Using a rat model of chronic diet-induced hypothyroidism initiated in the fetal period, we investigated the effects of prolonged reduced plasma thyroid hormone concentrations on the ovarian follicular reserve and ovulation rate in prepubertal (12-day-old) and adult (64-day-old and 120-day-old) rats. Besides, antioxidant gene expression, mitochondrial density and the occurrence of oxidative stress were analyzed...
April 2016: Biology of Reproduction
https://www.readbyqxmd.com/read/26946249/concentrations-of-thiocyanate-and-goitrin-in-human-plasma-their-precursor-concentrations-in-brassica-vegetables-and-associated-potential-risk-for-hypothyroidism
#16
REVIEW
Peter Felker, Ronald Bunch, Angela M Leung
Brassica vegetables are common components of the diet and have beneficial as well as potentially adverse health effects. Following enzymatic breakdown, some glucosinolates in brassica vegetables produce sulforaphane, phenethyl, and indolylic isothiocyanates that possess anticarcinogenic activity. In contrast, progoitrin and indolylic glucosinolates degrade to goitrin and thiocyanate, respectively, and may decrease thyroid hormone production. Radioiodine uptake to the thyroid is inhibited by 194 μmol of goitrin, but not by 77 μmol of goitrin...
April 2016: Nutrition Reviews
https://www.readbyqxmd.com/read/26840471/results-of-posterior-myectomy-for-the-treatment-of-children-with-chronic-constipation
#17
Mehran Peyvasteh, Shahnam Askarpour, Abdol-Hassan Talaiezadeh, Mohammad-Reza Imani, Hazhir Javaherizadeh
BACKGROUND AND OBJECTIVES: The aim of this study was to evaluate the result of posterior myectomy in children with chronic constipation who underwent to this surgery. METHODS: Forty eight children with chronic constipation who did not respond to diet, laxative, or enema were included. Children with abnormal barium enema showing transitional zone were excluded. Children with documented metabolic disease diabetes, and hypothyroidism were also excluded. All patients underwent posterior myectomy...
December 2015: Arquivos de Gastroenterologia
https://www.readbyqxmd.com/read/26795019/hexabromocyclododecane-hbcd-induced-changes-in-the-liver-proteome-of-eu-and-hypothyroid-female-rats
#18
I Miller, T Serchi, S Cambier, C Diepenbroek, J Renaut, J H J Van der Berg, C Kwadijk, A C Gutleb, E Rijntjes, A J Murk
Hexabromocyclododecane (HBCD) is a brominated flame retardant known for its low acute toxicity as observed in animal experiments. However, HBCD exposure can affect liver functioning and thyroid hormone (TH) status. As exact mechanisms are unknown and only limited toxicological data exists, a gel-based proteomic approach was undertaken. In a eu- and hypothyroid female rat model, rats were exposed to 3 and 30 mg/kg bw/day HBCD for 7 days via their diet, and exposure was related to a range of canonical endpoints (hormone status, body weight) available for these animals...
March 14, 2016: Toxicology Letters
https://www.readbyqxmd.com/read/26700485/effects-of-levothyroxine-replacement-or-suppressive-therapy-on-energy-expenditure-and-body-composition
#19
Mary H Samuels, Irina Kolobova, Anne Smeraglio, Dawn Peters, Jonathan Q Purnell, Kathryn G Schuff
BACKGROUND: Thyrotropin (TSH)-suppressive doses of levothyroxine (LT4) have adverse effects on bone and cardiac function, but it is unclear whether metabolic function is also affected. The objective of this study was to determine whether women receiving TSH-suppressive LT4 doses have alterations in energy expenditure or body composition. METHODS: This study was a cross-sectional comparison between three groups of women: 26 women receiving chronic TSH-suppressive LT4 doses, 80 women receiving chronic replacement LT4 doses, and 16 untreated euthyroid control women...
March 2016: Thyroid: Official Journal of the American Thyroid Association
https://www.readbyqxmd.com/read/26689565/comorbidities-concomitant-medications-and-diet-as-factors-affecting-levothyroxine-therapy-results-of-the-control-surveillance-project
#20
Marjorie McMillan, Keith S Rotenberg, Kevin Vora, Arnold B Sterman, Lionel Thevathasan, Michael F Ryan, Munish Mehra, Walter Sandulli
BACKGROUND: The CONTROL Surveillance Project was a comprehensive patient-based survey conducted among hypothyroid patients undergoing treatment. The primary objective of the study was to specifically quantify the prevalence of factors adversely affecting levothyroxine therapy. METHODS: Participants were selected from a large proprietary database. Those eligible for the study completed a 21-question survey. RESULTS: Of the eligible hypothyroid patients, 925 (92...
March 2016: Drugs in R&D
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