keyword
MENU ▼
Read by QxMD icon Read
search

Skin infection

keyword
https://www.readbyqxmd.com/read/29161590/skin-and-its-regenerative-powers-an-alliance-between-stem-cells-and-their-niche
#1
REVIEW
Kevin Andrew Uy Gonzales, Elaine Fuchs
Tissues have a natural capacity to replace dying cells and to heal wounds. This ability resides in resident stem cells, which self-renew, preserve, and repair their tissue during homeostasis and following injury. The skin epidermis and its appendages are subjected to daily assaults from the external environment. A high demand is placed on renewal and regeneration of the skin's barrier in order to protect the body from infection and dehydration and to heal wounds. This review focuses on the epithelial stem cells of skin, where they come from, where they reside, and how they function in normal homeostasis and wound repair...
November 20, 2017: Developmental Cell
https://www.readbyqxmd.com/read/29161422/prevalence-and-genetic-variability-of-human-polyomaviruses-6-and-7-in-healthy-skin-among-asymptomatic-individuals
#2
Yumiko Hashida, Tomonori Higuchi, Shigenobu Matsuzaki, Kimiko Nakajima, Shigetoshi Sano, Masanori Daibata
Background: Despite the pathogenetic potential of human polyomavirus 6 (HPyV6) and human polyomavirus 7 (HPyV7), they have been found in the normal skin of healthy individuals. However, little is known about the prevalence, infection levels, and geographical variations of these polyomaviruses in the skin. Methods: Using skin swabs from 470 participants aged 2-98 years, we estimated the prevalence of copy numbers of HPyV6 and HPyV7 with respect to age and ethnicity...
November 17, 2017: Journal of Infectious Diseases
https://www.readbyqxmd.com/read/29161328/use-of-quantiferon%C3%A2-tb-gold-in-tube-culture-supernatants-for-measurement-of-antibody-responses
#3
Simon G Kimuda, Irene Andia-Biraro, Moses Egesa, Bernard S Bagaya, John G Raynes, Jonathan Levin, Alison M Elliott, Stephen Cose
QuantiFERON®-TB Gold in-tube (QFT-GIT) supernatants may be important samples for use in assessment of anti-tuberculosis (TB) antibodies when only limited volumes of blood can be collected and when a combination of antibody and cytokine measurements are required. These analytes, when used together, may also have the potential to differentiate active pulmonary TB (APTB) from latent TB infection (LTBI). However, few studies have explored the use of QFT-GIT supernatants for investigations of antibody responses...
2017: PloS One
https://www.readbyqxmd.com/read/29160902/proportion-and-number-of-cancer-cases-and-deaths-attributable-to-potentially-modifiable-risk-factors-in-the-united-states
#4
Farhad Islami, Ann Goding Sauer, Kimberly D Miller, Rebecca L Siegel, Stacey A Fedewa, Eric J Jacobs, Marjorie L McCullough, Alpa V Patel, Jiemin Ma, Isabelle Soerjomataram, W Dana Flanders, Otis W Brawley, Susan M Gapstur, Ahmedin Jemal
Contemporary information on the fraction of cancers that potentially could be prevented is useful for priority setting in cancer prevention and control. Herein, the authors estimate the proportion and number of invasive cancer cases and deaths, overall (excluding nonmelanoma skin cancers) and for 26 cancer types, in adults aged 30 years and older in the United States in 2014, that were attributable to major, potentially modifiable exposures (cigarette smoking; secondhand smoke; excess body weight; alcohol intake; consumption of red and processed meat; low consumption of fruits/vegetables, dietary fiber, and dietary calcium; physical inactivity; ultraviolet radiation; and 6 cancer-associated infections)...
November 21, 2017: CA: a Cancer Journal for Clinicians
https://www.readbyqxmd.com/read/29160525/colonic-basidiobolomycosis-with-liver-involvement-masquerading-as-gastrointestinal-lymphoma-a-case-report-and-literature-review
#5
Omid Reza Zekavat, Babak Abdolkarimi, Gholamreza Pouladfar, Gholamreza Fathpour, Maral Mokhtari, Nader Shakibazad
Basidiobolomycosis is an unusual fungal skin infection that rarely involves the gastrointestinal tract. This study reported a 5-year-old boy with gastrointestinal basidiobolomycosis that had been misdiagnosed as gastrointestinal lymphoma. He was treated by surgical resection and a combination of posaconazole and amphotericin B deoxycholate with an acceptable response and no recurrence.
September 2017: Revista da Sociedade Brasileira de Medicina Tropical
https://www.readbyqxmd.com/read/29160352/genital-myiasis-associated-with-genital-piercing-case-report
#6
Daniel Melecchi Freitas, Flavio Aranovich, José Nicolau Olijnyk, Renan Lemos
CONTEXT: Myiasis is caused by larval infestation that usually occurs in exposed wounds. Dermatobia hominis is the most common fly species responsible for this parasitic infection. Genital piercing is an ornamental practice used in certain social circles. At placement, it transverses the skin surface and, as such, may be related to complications. CASE REPORT: We report a case of a 31-year-old man with a history of wound infection secondary to genital piercing who was exposed to an environment with flies, leading to myiasis...
November 9, 2017: São Paulo Medical Journal, Revista Paulista de Medicina
https://www.readbyqxmd.com/read/29160219/complete-sequences-of-4-viral-hemorrhagic-septicemia-virus-ivb-isolates-and-their-virulence-in-northern-pike-fry
#7
Rodman G Getchell, Emily R Cornwell, Steven Bogdanowicz, Jose Andrés, William N Batts, Gael Kurath, Rachel Breyta, Joanna G Choi, John M Farrell, Paul R Bowser
Four viral hemorrhagic septicemia virus (VHSV) genotype IVb isolates were sequenced, their genetic variation explored, and comparative virulence assayed with experimental infections of northern pike Esox lucius fry. In addition to the type strain MI03, the complete 11183 bp genome of the first round goby Neogobius melanostomus isolate from the St. Lawrence River, and the 2013 and 2014 isolates from gizzard shad Dorosoma cepedianum die-offs in Irondequoit Bay, Lake Ontario and Dunkirk Harbor, Lake Erie were all deep sequenced on an Illumina platform...
November 21, 2017: Diseases of Aquatic Organisms
https://www.readbyqxmd.com/read/29159979/ultrasound-microbubbles-enhance-the-activity-of-vancomycin-against-staphylococcus-epidermidis-biofilms-in-vivo
#8
Ying Dong, Junshuai Li, Pan Li, Jialin Yu
OBJECTIVES: Staphylococcus epidermidis is the predominant pathogen of device-associated infections. By forming biofilms on the device surface, S epidermidis has substantial resistance to antibiotics and is difficult to eradicate. This study aimed to explore the synergistic effect of ultrasound (US)-mediated microbubbles combined with vancomycin on S epidermidis biofilms in a rabbit model. METHODS: Two polytetrafluoroethene catheters with preformed S epidermidis biofilms were implanted subcutaneously in a rabbit, one on either side of the spine...
November 21, 2017: Journal of Ultrasound in Medicine: Official Journal of the American Institute of Ultrasound in Medicine
https://www.readbyqxmd.com/read/29159502/antifungal-activity-of-myrtus-communis-against-malassezia-sp-isolated-from-the-skin-of-patients-with-pityriasis-versicolor
#9
Aleksandra Barac, Matthew Donadu, Donatella Usai, Vesna Tomic Spiric, Vittorio Mazzarello, Stefania Zanetti, Ema Nikolic, Goran Stevanovic, Natasa Popovic, Salvatore Rubino
The increasing incidence of fungal infections and antifungal resistance has prompted the search for novel antifungal drugs and alternative agents. We explored the antifungal activity of Myrtus communis essential oil (EO) against Malassezia sp. isolated from the skin of patients with pityriasis versicolor. These broad-spectrum antimicrobial activities of M. communis EO and its potent inhibiting activity on Malassezia growth deserve further research with aim to considerate this EO as candidate for topical use in treatment of skin diseases...
November 20, 2017: Infection
https://www.readbyqxmd.com/read/29159027/a-case-of-paracoccidioidomycosis-due-to-paracoccidioides-lutzii-presenting-sarcoid-like-form
#10
Luiza Sarmento Tatagiba, Luana Bridi Pivatto, Álvaro A Faccini-Martínez, Paulo Mendes Peçanha, Tânia Regina Grão Velloso, Sarah Santos Gonçalves, Anderson Messias Rodrigues, Zoilo Pires Camargo, Aloísio Falqueto
Paracoccidioidomycosis (PCM) is a fungal disease caused by Paracoccidioides spp., which can cause a systemic granulomatous infection with tegumentary and visceral involvement. Sarcoid-like skin lesions are uncommon and can be misdiagnosed due to similarities with other granulomatous diseases. We report a case of a women presenting with erythematous infiltrated plaques on her face that was treated for leprosy and rosacea with no response and was later diagnosed with PCM, presenting positive serology for Paracoccidioides lutzii...
March 2018: Medical Mycology Case Reports
https://www.readbyqxmd.com/read/29158645/evaluation-of-functional-outcome-of-pilon-fractures-managed-with-limited-internal-fixation-and-external-fixation-a-prospective-clinical-study
#11
Umesh Kumar Meena, Mahesh Chand Bansal, Prateek Behera, Rahul Upadhyay, Gyan Chand Gothwal
Introduction: The management of pilon fractures is controversial primarily due to the high rate of complications irrespective of the mode of treatment. Limited internal fixation with external fixation is associated with minimal soft tissue handling. This may reduce the chances of wound dehiscence and infection. This study was designed to evaluate the functional and clinical outcomes in patients treated with limited internal fixation combined with external fixation in pilon fractures. Material and methods: This study was conducted as a prospective clinical study on 56 skeletally mature patients with closed fractures with poor skin condition, and with open grade 1 and grade 2 distal tibial intra-articular fractures...
November 2017: Journal of Clinical Orthopaedics and Trauma
https://www.readbyqxmd.com/read/29158644/injury-mechanism-fracture-characteristics-and-clinical-treatment-of-pilon-fracture-with-intact-fibula-a-retrospective-study-of-23-pilon-fractures
#12
Jiang Liangjun, Zheng Qiang, Li Hang, Pan Zhijun
Objective: The effect of intact fibula on pilon fracture is not completely elucidated. We retrospectively analysed pilon fractures with intact fibula at our hospital over a 4 year period to understand the injury mechanism, fracture characteristics, treatment strategy and prognosis of this fracture. Methods: Pilon fracture patients with intact fibula treated in our hospital from January 2010 to December 2014 were observed. OA/ATO fracture type, Ruedi-Allgower classification and fracture characteristics were summarised...
November 2017: Journal of Clinical Orthopaedics and Trauma
https://www.readbyqxmd.com/read/29158433/whole-genome-characterization-of-bacillus-cereus-associated-with-specific-disease-manifestations
#13
T Chang, J W Rosch, Z Gu, H Hakim, C Hewitt, A Gaur, G Wu, R T Hayden
Bacillus cereus remains an important cause of infections, particularly in immunocompromised hosts. While typically associated with enteric infections, disease manifestations can be quite diverse and include skin infections, bacteremia, pneumonia, and meningitis. Whether there are any genetic correlates of bacterial strains with particular clinical manifestations remains unknown. To address this gap in understanding we undertook whole genome analysis of B. cereus strains isolated from patients with a range of disease manifestations, including non-invasive colonizing disease, superficial skin infections, and invasive bacteremia...
November 20, 2017: Infection and Immunity
https://www.readbyqxmd.com/read/29158430/characterization-of-stress-and-innate-immunity-resistance-of-wild-type-and-%C3%AE-p66-borrelia-burgdorferi
#14
Michael W Curtis, Beth L Hahn, Kai Zhang, Chunhao Li, Richard T Robinson, Jenifer Coburn
Borrelia burgdorferi is a causative agent of Lyme disease, the most common arthropod-borne disease in the United States. B. burgdorferi evades host immune defenses to establish a persistent, disseminated infection. Previous work showed that P66-deficient B. burgdorferi (Δp66) is cleared quickly after inoculation in mice. We demonstrate that Δp66 is rapidly cleared from the skin inoculation site prior to dissemination. The rapid clearance of Δp66 is not due to inherent defects in multiple properties that might affect infectivity: bacterial outer membrane integrity, motility, chemotactic response, or nutrient acquisition...
November 20, 2017: Infection and Immunity
https://www.readbyqxmd.com/read/29158281/pharmacokinetics-and-safety-of-omadacycline-in-subjects-with-impaired-renal-function
#15
Jolene K Berg, Evan Tzanis, Lynne Garrity-Ryan, Stephen Bai, Surya Chitra, Amy Manley, Stephen Villano
Many antibiotics require dosing adjustments in patients with renal impairment and/or in those undergoing hemodialysis. Omadacycline, the first aminomethylcycline antibiotic in late-stage clinical development, displays activity against a broad-spectrum of bacterial pathogens, including resistant strains. Data from completed phase 3 acute bacterial skin and skin structure infections (ABSSSI) and community-acquired bacterial pneumonia (CABP) studies showed intravenous (IV) to once-daily oral omadacycline to be clinically effective and well tolerated...
November 20, 2017: Antimicrobial Agents and Chemotherapy
https://www.readbyqxmd.com/read/29158144/ceftolozane-tazobactam-in-the-treatment-of-osteomyelitis-and-skin-and-soft-tissue-infections-due-to-extensively-drug-resistant-pseudomonas-aeruginosa-clinical-and-microbiological-outcomes
#16
B Dietl, I Sánchez, P Arcenillas, E Cuchi, L Gómez, F J González de Molina, L Boix-Palop, J Nicolás, E Calbo
Infections due to multidrug-resistant bacteria (MDRB) are currently a clinical challenge, mainly in elderly patients. Ceftolozane/tazobactam spectrum, safety and efficacy make it an attractive option for MDRB beyond the indications approved to date. We report our experience with ceftolozane/tazobactam in 4 cases of osteomyelitis and 3 skin-soft-tissue infections due to extensively-drug-resistant Pseudomonas aeruginosa.
November 17, 2017: International Journal of Antimicrobial Agents
https://www.readbyqxmd.com/read/29157841/acute-management-of-high-energy-lisfranc-injuries-a-simple-approach
#17
Dolfi Herscovici, Julia M Scaduto
INTRODUCTION: The aims of this study were to (1) describe the use of the K-wire for the initial management of high-energy Lisfranc dislocations or fracture dislocations, (2) to evaluate whether this standalone technique allowed for adequate reduction of these injuries, (3) to evaluate whether reductions were maintained until definitive fixation was performed, (4) and to determine if it contributed to any increase in complications prior to or after definitive fixation. PATIENTS AND METHODS: A retrospective review was performed on all patients who presented with tarsometatarsal injuries from January 2005 through June 2015...
November 16, 2017: Injury
https://www.readbyqxmd.com/read/29157827/supplementation-with-tocotrienols-from-bixa-orellana-improves-the-in-vivo-efficacy-of-daptomycin-against-methicillin-resistant-staphylococcus-aureus-in-a-mouse-model-of-infected-wound
#18
Elisa Pierpaoli, Fiorenza Orlando, Oscar Cirioni, Oriana Simonetti, Andrea Giacometti, Mauro Provinciali
BACKGROUND: Methicillin-resistant Staphylococcus aureus (MRSA) is a common cause of skin and soft-tissue infection worldwide. An adequate immune response acts as a first line of defence against infections and therefore plays an essential role in the maintenance of health. Tocotrienols (T3s), the lesser known isomers of vitamin E, possess many biological properties and have been recognized as immunomodulators. PURPOSE: The aim of this study was to investigate whether the in vivo supplementation with a mixture of 87...
December 1, 2017: Phytomedicine: International Journal of Phytotherapy and Phytopharmacology
https://www.readbyqxmd.com/read/29157732/rnase-7-strongly-promotes-tlr9-mediated-dna-sensing-by-human-plasmacytoid-dendritic-cells
#19
V Kopfnagel, S Wagenknecht, J Harder, K Hofmann, M Kleine, A Buch, B Sodeik, T Werfel
Plasmacytoid dendritic cells (pDCs) were described to accumulate in the skin of patients with psoriasis and to be recruited into the dermis upon allergen challenge in atopic dermatitis. Importantly, activation of pDCs in the skin has been identified as important initiator of psoriasis development. RNase 7 is one of the major antimicrobial peptides (AMP) secreted by keratinocytes and is expressed in significantly higher amounts in lesional skin of patients with atopic dermatitis or psoriasis than in healthy individuals...
November 17, 2017: Journal of Investigative Dermatology
https://www.readbyqxmd.com/read/29157267/transcriptomic-analysis-reveals-the-key-immune-related-signalling-pathways-of-sebastiscus-marmoratus-in-response-to-infection-with-the-parasitic-ciliate-cryptocaryon-irritans
#20
Fei Yin, Dong Qian
BACKGROUND: False kelpfish (Sebastiscus marmoratus) is one of the target species in artificial breeding in China, and is susceptible to infection by Cryptocaryon irritans, which is an obligate parasitic ciliate that lives in the epithelium of the fish gills, skin and fins. Here, we sought to understand the mechanisms of molecular immunity of S. marmoratus against C. irritans infection. METHODS: We carried out an extensive analysis of the transcriptome of S. marmoratus immune-related tissues...
November 21, 2017: Parasites & Vectors
keyword
keyword
49621
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"