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management of type 2 diabetes mellitus

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https://www.readbyqxmd.com/read/28717335/evaluation-of-therapeutic-effectiveness-of-prescribed-medications-in-patients-with-type-2-diabetes-mellitus-findings-from-a-tertiary-care-hospital-lahore-pakistan
#1
Bareera Rana, Allah Bukhsh, Tahir Mehmood Khan, Ammar Sarwar, Muhammad Ovais Omer, Shazia Qasim Jamshed
AIM: The present study was aimed to highlight the current prescribing pattern of oral hypoglycemia in type 2 diabetes mellitus and to evaluate the therapeutic effectiveness of these therapeutic categories in achieving target glycemic control. METHODS: This is a prospective, cross-sectional, observational study of 6 months' duration conducted in a tertiary care hospital of Lahore, Pakistan. RESULTS: The current research recruited 145 patients presented in diabetes management center of a tertiary care hospital in Lahore, Pakistan...
April 2017: Journal of Pharmacy & Bioallied Sciences
https://www.readbyqxmd.com/read/28717115/coronary-artery-disease-and-type-2-diabetes-mellitus
#2
Ryo Naito, Katsumi Miyauchi
Type 2 diabetes mellitus (T2DM) is a major risk factor of coronary artery diseases (CAD). Clinical outcomes in CAD with T2DM are poor despite improvement in medications and intervention devices. Coronary artery bypass grafting (CABG) is superior to percutaneous coronary intervention (PCI) in treating diabetic patients with multivessel coronary artery diseases (MVD). However, selecting a revascularization strategy should depend not only on the lesion complexity but also on the patient's background and comorbidities...
July 14, 2017: International Heart Journal
https://www.readbyqxmd.com/read/28716404/partial-jejunal-diversion-using-an-incisionless-magnetic-anastomosis-system-1-year-interim-results-in-subjects-with-obesity-and-diabetes
#3
Evžen Machytka, Marek Bužga, Pavel Zonca, David B Lautz, Marvin Ryou, Donald C Simonson, Christopher C Thompson
BACKGROUND AND AIMS: The majority of patients with type 2 diabetes mellitus (T2DM) have obesity. Studies show that bariatric surgery is superior to medical treatment for remission of T2DM. Nevertheless, very few patients undergo surgery, and a less-invasive endoscopic alternative is desirable. METHODS: This was a single-arm first-in-human pilot study, designed to evaluate the technical feasibility, safety, and clinical performance of the incisionless magnetic anastomosis system (IMAS) in creation of a partial jejunal diversion (PJD)...
July 14, 2017: Gastrointestinal Endoscopy
https://www.readbyqxmd.com/read/28713443/e-healthcare-for-diabetes-mellitus-type-2-patients-a-randomised-controlled-trial-in-slovenia
#4
Rade Iljaž, Andrej Brodnik, Tatjana Zrimec, Iztok Cukjati
BACKGROUND: Telemonitoring and web-based interventions are increasingly used in primary-care practices in many countries for more effective management of patients with diabetes mellitus (DM). A new approach in treating patients with diabetes mellitus in family practices, based on ICT use and nurse practitioners, has been introduced and evaluated in this study. METHOD: Fifteen Slovene family practices enrolled 120 DM patients treated only with a diet regime and/or tablets into the study...
September 2017: Zdravstveno Varstvo
https://www.readbyqxmd.com/read/28712011/fgf21-attenuates-high-fat-diet-induced-cognitive-impairment-via-metabolic-regulation-and-anti-inflammation-of-obese-mice
#5
Qingzhi Wang, Jing Yuan, Zhanyang Yu, Li Lin, Yinghua Jiang, Zeyuan Cao, Pengwei Zhuang, Michael J Whalen, Bo Song, Xiao-Jie Wang, Xiaokun Li, Eng H Lo, Yuming Xu, Xiaoying Wang
Accumulating studies suggest that overnutrition-associated obesity may lead to development of type 2 diabetes mellitus and metabolic syndromes (MetS). MetS and its components are important risk factors of mild cognitive impairment, age-related cognitive decline, vascular dementia, and Alzheimer's disease. It has been recently proposed that development of a disease-course modification strategy toward early and effective risk factor management would be clinically significant in reducing the risk of metabolic disorder-initiated cognitive decline...
July 15, 2017: Molecular Neurobiology
https://www.readbyqxmd.com/read/28711513/the-effectiveness-of-cognitive-function-stress-management-training-in-glycemic-control-in-children-and-in-mental-health-of-mother-caring-for-child-with-type-1-diabetes-mellitus
#6
Mozhdeh Saghaei, Pouya Omidi, Elham Hashemi Dehkordi, Parvin Safavi
AIM: The study was aimed to evaluate the effectiveness of a training course of cognitive-behavioral stress management in glycaemia regulation in children with type 1 diabetes mellitus as well as in mental health status of their mothers. MATERIALS AND METHODS: Fifty children with type 1 diabetes mellitus and their mothers were selected and randomly assigned into two groups. A group of mothers (n=25; as experimental one besides their children) passed a course, eight 2-h sessions, on the cognitive-behavioral and stress management, and the control group received the usual care...
July 3, 2017: Diabetes & Metabolic Syndrome
https://www.readbyqxmd.com/read/28709459/association-of-lipocalin-2-level-glycemic-status-and-obesity-in-type-2-diabetes-mellitus
#7
Areej E Elkhidir, Halima B Eltaher, Abdelrahim O Mohamed
BACKGROUND: Management of type 2 diabetes mellitus aims to maintain a normal glycemic status, which if not, it may lead to acute and/or chronic diabetic complications. Earlier studies found Lipocalin-2 elevated in complications associated with type 2 diabetes mellitus such as ischemic heart disease. These lipocalin-2 changes had been linked to obesity and uncontrolled diabetes. So, it could be useful to understand the effect of glycemic control and obesity on lipocalin-2. METHODS: This was a case control study...
July 14, 2017: BMC Research Notes
https://www.readbyqxmd.com/read/28708482/metabolic-surgery-for-treating-type-2-diabetes-mellitus-now-supported-by-the-world-s-leading-diabetes-organizations
#8
REVIEW
Philip R Schauer, Zubaidah Nor Hanipah, Francesco Rubino
The term metabolic surgery describes bariatric surgical procedures used primarily to treat type 2 diabetes and related metabolic conditions. Originally, bariatric surgery was used as an alternative weight-loss therapy for patients with severe obesity, but clinical data revealed its metabolic benefits in patients with type 2 diabetes. Metabolic surgery is more effective than lifestyle or medical management in achieving glycemic control, sustained weight loss, and reducing diabetes comorbidities. Perioperative adverse events are similar to other gastrointestinal surgeries...
July 2017: Cleveland Clinic Journal of Medicine
https://www.readbyqxmd.com/read/28708481/antiobesity-drugs-in-the-management-of-type-2-diabetes-a-shift-in-thinking
#9
REVIEW
Bartolome Burguera, Khawla F Ali, Juan P Brito
Antiobesity medications can improve metabolic control for patients with type 2 diabetes mellitus (DM) and obesity, but are underutilized. In this review, we describe the role of antiobesity drugs in the context of medically supervised and comprehensive weight-loss interventions and propose a pragmatic therapeutic algorithm for patients with type 2 DM and obesity that incorporates the use of antiobesity drugs early in the course of management.
July 2017: Cleveland Clinic Journal of Medicine
https://www.readbyqxmd.com/read/28705834/visit-to-visit-variations-in-fasting-plasma-glucose-and-hba1c-associated-with-an-increased-risk-of-alzheimer-disease-taiwan-diabetes-study
#10
Tsai-Chung Li, Chun-Pai Yang, Shih-Ting Tseng, Chia-Ing Li, Chiu-Shong Liu, Wen-Yuan Lin, Kai-Lin Hwang, Sing-Yu Yang, Jen-Huai Chiang, Cheng-Chieh Lin
OBJECTIVE: The relationship between glycemic variability and the incidence of Alzheimer disease (AD) in patients with type 2 diabetes mellitus (T2DM) is unclear. The aim of this study was to examine visit-to-visit variations in fasting plasma glucose (FPG) and glycated hemoglobin (HbA1c) represented by the coefficient of variation (CV) and to determine whether they were independently associated with AD, irrespective of HbA1c and other traditional risk factors in such patients. RESEARCH DESIGN AND METHODS: Patients with T2DM enrolled in the National Diabetes Care Management Program, age ≥60 years, and without diagnosis of AD (n = 16,706) were included in the study...
July 13, 2017: Diabetes Care
https://www.readbyqxmd.com/read/28704857/the-real-life-effectiveness-and-care-patterns-of-type-2-diabetes-management-in-greece
#11
Emmanuel Pagkalos, Anastasia Thanopoulou, Christos Sampanis, Stavros Bousboulas, Andreas Melidonis, Nicholas Tentolouris, Theodoros Alexandrides, Ilias Migdalis, Eugenia Karamousouli, Nikolaos Papanas
Aim To investigate the prevalence of hypoglycaemia during sulfonylurea (SU) treatment of type 2 diabetes mellitus (T2DM) in Greece and its influence on glycaemic control, treatment adherence and quality of life (QoL). Patients and methods This was a retrospective cross-sectional study. We included 383 T2DM patients ≥30 years old on treatment with SU in monotherapy or in combination with metformin for at least 6 months. Patients were requested to fill in retrospective questionnaires on hypoglycaemia experience, adherence, weight gain and lifestyle/behavioural factors along with QoL (EQ-5D-3L), treatment satisfaction (TSQM), and fear of hypoglycaemia (HFS-II Worry scale)...
July 13, 2017: Experimental and Clinical Endocrinology & Diabetes
https://www.readbyqxmd.com/read/28701461/opioid-use-disorder-and-type-2-diabetes-mellitus-effect-of-participation-in-buprenorphine-naloxone-substitution-programs-on-glycemic-control
#12
Devon Tilbrook, Jeffrey Jacob, Pierre Parsons, Craig Edwards, Kassandra Loewen, Len Kelly
OBJECTIVE: To measure the effect of buprenorphine-naloxone as opioid substitution therapy on glycemic control in patients with type 2 diabetes mellitus and opioid use disorder. DESIGN: Retrospective cohort study and secondary data analysis. SETTING: Northwestern Ontario. PARTICIPANTS: Patients with diabetes receiving opioid substitution therapy, as well as patients with diabetes only, who live in 6 remote First Nations communities...
July 2017: Canadian Family Physician Médecin de Famille Canadien
https://www.readbyqxmd.com/read/28700102/electronic-messaging-intervention-for-management-of-cardiovascular-risk-factors-in-type-2-diabetes-mellitus-a-randomised-controlled-trial
#13
Ronghua Fang, Xuexue Deng
AIM: To determine the effectiveness of an electronic messaging support service for management of cardiovascular risk factors in diabetes patients. BACKGROUND: Micro letter and short message service are widely used, but their health education benefit for people with type 2 diabetes mellitus has not been investigated. DESIGN: Convenience sample study with randomized group assignment. METHODS: Participants completed survey questionnaires, physical and laboratory evaluations between May 2015 and May 2016, and were then randomly assigned to two groups for receipt of a Micro letter + Short message or a Phone call (control)...
July 12, 2017: Journal of Clinical Nursing
https://www.readbyqxmd.com/read/28699483/physical-disability-and-diabetes-mellitus-qualitative-exploration-of-patients-perception-and-behavior
#14
Syed Wasif Gillani, Syed Azhar Syed Sulaiman, Mohi Iqbal Mohammad Abdul, Sherif Yahya Saad
BACKGROUND: Disability is a key indicator implicating both overall morbidity and success of public health efforts to compress the period of morbidity among geriatrics for the overall population. Disabilities are more prevalent among diabetics than among those without diabetes. OBJECTIVE: This study aimed to determine self-monitoring practices, awareness to dietary modifications and barriers to medication adherence among physically disabled type 2 diabetes mellitus patients...
July 10, 2017: Current Diabetes Reviews
https://www.readbyqxmd.com/read/28695302/argatroban-attenuates-diabetic-cardiomyopathy-in-rats-by-reducing-fibrosis-inflammation-apoptosis-and-protease-activated-receptor-expression
#15
Yogesh Bulani, Shyam Sunder Sharma
PURPOSE: Chronic diabetes is associated with cardiovascular dysfunctions. Diabetic cardiomyopathy (DCM) is one of the serious cardiovascular complications associated with diabetes. Despite significant efforts in understanding the pathophysiology of DCM, management of DCM is not adequate due to its complex pathophysiology. Recently, involvement of protease-activated receptors (PARs) has been postulated in cardiovascular diseases. These receptors are activated by thrombin, trypsin, or other serine proteases...
July 10, 2017: Cardiovascular Drugs and Therapy
https://www.readbyqxmd.com/read/28694704/health-care-provider-experience-with-canagliflozin-in-real-world-clinical-practice-favorability-treatment-patterns-and-patient-outcomes
#16
Susan C Bolge, Natalia M Flores, Shu Huang, Jennifer Cai
PURPOSE: This study describes how health care providers approach canagliflozin for the treatment of patients with type 2 diabetes mellitus (T2DM) in the real world. PATIENTS AND METHODS: An Internet-based questionnaire was completed by 101 endocrinologists, 101 primary care physicians, and 100 nurse practitioners/physician assistants (NP/PAs). Health care providers were required to have experience prescribing or managing patients using canagliflozin to be included in the study...
2017: International Journal of General Medicine
https://www.readbyqxmd.com/read/28693595/biochemical-characterization-and-1-h-nmr-based-metabolomics-revealed-melicope-lunu-ankenda-leaf-extract-a-potent-anti-diabetic-agent-in-rats
#17
Mizher Hezam Al-Zuaidy, Muhammad Waseem Mumtaz, Azizah Abdul Hamid, Amin Ismail, Suhaila Mohamed, Ahmad Faizal Abdul Razis
BACKGROUND: Type 2 diabetes mellitus (T2DM) is a metabolic disorder characterized by continuous hyperglycemia associated with insulin resistance and /or reduced insulin secretion. There is an emerging trend regarding the use of medicinal plants for the treatment of diabetes mellitus. Melicope lunu-ankenda (ML) is one of the Melicope species belonging to the family Rutaceae. In traditional medicines, its leaves and flowers are known to exhibit prodigious health benefits. The present study aimed at investigating anti-diabetic effect of Melicope lunu-ankenda (ML) leaves extract...
July 10, 2017: BMC Complementary and Alternative Medicine
https://www.readbyqxmd.com/read/28689733/long-term-outcome-of-laparoscopic-sleeve-gastrectomy-from-a-single-center-in-mainland-china
#18
Pankaj Kumar Hans, Wei Guan, Shibo Lin, Hui Liang
BACKGROUND/OBJECTIVE: Laparoscopic sleeve gastrectomy (LSG) is at present the most popular bariatric procedure due to its significant weight loss, remission of co-morbidities, and acceptable morbidity. But, there are not many studies showing its long term efficacy and safety in Chinese patients. The aim of this study is to give five results of LSG in terms of weight loss, co-morbidity (Type 2 diabetes mellitus) resolution and possible complications from a single center in mainland China...
July 7, 2017: Asian Journal of Surgery
https://www.readbyqxmd.com/read/28689524/effects-of-supervised-structured-aerobic-exercise-training-program-on-interleukin-6-nitric-oxide-synthase-1-and-cyclooxygenase-2-in-type-2-diabetes-mellitus
#19
Hossein Karimi, Syed Shakil Ur Rehman, Syed Amir Gillani
OBJECTIVE: To determine the effects of supervised structured aerobic exercise training (SSAET) program on interleukin-6 (IL-6), nitric oxide synthase 1 (NOS-1), and cyclooxygenase-2 (COX-2) in type 2 diabetes mellitus (T2DM). STUDY DESIGN: Randomized controlled trial. PLACE AND DURATION OF STUDY: Riphah Rehabilitation and Research Centre, Railways General Hospital, Rawalpindi, from January 2015 to June 2016. METHODOLOGY: Patients of either gender of minimum one year history of T2DM ranging from 40-70 years of age were included...
June 2017: Journal of the College of Physicians and Surgeons—Pakistan: JCPSP
https://www.readbyqxmd.com/read/28684676/integrated-assessment-of-pharmacological-and-nutritional-cardiovascular-risk-management-blood-pressure-control-in-the-diabetes-and-lifestyle-cohort-twente-dialect
#20
Christina M Gant, S Heleen Binnenmars, Else van den Berg, Stephan J L Bakker, Gerjan Navis, Gozewijn D Laverman
Cardiovascular risk management is an integral part of treatment in Type 2 Diabetes Mellitus (T2DM), and requires pharmacological as well as nutritional management. We hypothesize that a systematic assessment of both pharmacological and nutritional management can identify targets for the improvement of treatment quality. Therefore, we analysed blood pressure (BP) management in the DIAbetes and LifEstyle Cohort Twente (DIALECT). DIALECT is an observational cohort from routine diabetes care, performed at the ZGT Hospital (Almelo and Hengelo, The Netherlands)...
July 6, 2017: Nutrients
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