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management of type 2 diabetes mellitus

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https://www.readbyqxmd.com/read/29457694/exploring-self-management-on-glycemic-control-using-a-modified-information-motivation-behavioral-skills-model-in-type-2-diabetes-mellitus-patients-in-shanghai-china-a-cross-sectional-study
#1
Qi Chen, Huwen Wang, Yichen Wang, Zezhou Wang, DaiJun Zhao, Yong Cai
BACKGROUND: The utility and maturity of the original Information-Motivation-Behavioral Skills (IMB) model have been verified in Type 2 Diabetes Mellitus (T2DM) patients. But little research has clarified whether the model has effect on glycemic control. The main purpose of this study is to modify the IMB model to explore self-management on glycemic control in T2DM patients in Shanghai, China. METHODS: A cross-sectional study was conducted using a convenience sampling method between June and August 2015 in three tertiary hospitals and four community health service centers...
February 19, 2018: Journal of Diabetes
https://www.readbyqxmd.com/read/29453672/the-effect-of-n-3-pufas-on-circulating-adiponectin-and-leptin-in-patients-with-type-2-diabetes-mellitus-a-systematic-review-and-meta-analysis-of-randomized-controlled-trials
#2
Azam Rezaei Farimani, Mitra Hariri, Mohsen Azimi-Nezhad, Abasalt Borji, Sadegh Zarei, Elham Hooshmand
AIM: N-3 PUFAs can potentially influence levels of inflammatory and non-inflammatory adipokines. Given the contradictory effects of n-3 PUFAs on serum levels of adipokines in type 2 diabetes, we conducted a systematic review and meta-analysis study of randomized placebo-controlled clinical trials that examined the effects of n-3 PUFAs on serum levels of leptin and adiponectin in patients with type 2 diabetes. METHODS: The electronic databases, without regard to language restrictions including PubMed/Medline, Google Scholar, SCOPUS and ISI Web of Science until August 2017, were used to identify randomized controlled trials that assessed the effect of n-3 PUFAs on serum leptin and adiponectin concentrations in type 2 diabetes...
February 16, 2018: Acta Diabetologica
https://www.readbyqxmd.com/read/29449295/management-of-type-2-diabetes-mellitus-in-people-with-severe-mental-illness-an-online-cross-sectional-survey-of-healthcare-professionals
#3
Hayley McBain, Frederique Lamontagne-Godwin, Mark Haddad, Alan Simpson, Jacqui Chapman, Julia Jones, Chris Flood, Kathleen Mulligan
OBJECTIVES: To establish healthcare professionals' (HCPs) views about clinical roles, and the barriers and enablers to delivery of diabetes care for people with severe mental illness (SMI). DESIGN: Cross-sectional, postal and online survey. SETTING: Trusts within the National Health Service, mental health and diabetes charities, and professional bodies. PARTICIPANTS: HCPs who care for people with type 2 diabetes mellitus (T2DM) and/or SMI in the UK...
February 15, 2018: BMJ Open
https://www.readbyqxmd.com/read/29449147/relation-between-hba-1c-and-incident-cardiovascular-disease-over-a-period-of-6-years-in-the-hong-kong-population
#4
E Y F Wan, E Y T Yu, C S C Fung, W Y Chin, D Y T Fong, A K C Chan, C L K Lam
AIM: The current trend on diabetes management advocates replacing the paradigm from a uniform to an individualized patient-centered haemoglobin A 1c (HbA 1c ) target, but there is no consensus on the optimal HbA 1c level. The study aimed at examining the association between HbA 1c and the risk of cardiovascular diseases (CVD) for diabetic patients with different characteristics, in order to identify patient-centered treatment targets. METHODS: A retrospective cohort study was conducted on 115,782 Chinese adult primary care patients with type 2 diabetes mellitus (DM) but no known CVD history, who were prescribed antidiabetic medications in 2010-2011...
February 3, 2018: Diabetes & Metabolism
https://www.readbyqxmd.com/read/29449103/salmon-calcitonin-and-omega-3-fatty-acids-exhibit-antagonistic-and-non-additive-effects-in-experimental-diabetes
#5
Wale Johnson Adeyemi, Luqman Aribidesi Olayaki
Because optimising therapy for the management of diabetes mellitus remains challenging, the study investigated the effects of salmon calcitonin (Sct) and/or omega-3 fatty acids (N-3 - eicosapentaenoic acid and docosahexaenoic acid-3:2), compared to metformin, on selected biochemical parameters in male Wistar rats, in an experimental model of diabetes. Forty rats were used for this study. They were divided into eight groups of five rats each, which included: Normal control; Diabetic (D) control; D + N-3; D + low dose Sct (Sct...
February 9, 2018: Pathophysiology: the Official Journal of the International Society for Pathophysiology
https://www.readbyqxmd.com/read/29449096/evaluating-the-impact-of-diabetes-self-management-education-methods-on-knowledge-attitudes-and-behaviours-of-adult-patients-with-type-2-diabetes-mellitus
#6
Laura Adam, Colleen O'Connor, Alicia C Garcia
OBJECTIVES: Diabetes self-management refers to all activities patients undertake to care for their illness, promote health and prevent the long- and short-term effects of diabetes. This study compared the effectiveness of 2 diabetes self-management education methods by examining changes in glycated hemoglobin (A1C) levels and knowledge, attitudes and behaviours (KABs) after traditional group education (TE) or with diabetes conversation maps (CMs). The CMs group was postulated to show greater decrease in A1C levels and improved KABs scores compared to the TE group...
November 23, 2017: Canadian Journal of Diabetes
https://www.readbyqxmd.com/read/29448006/plasma-triglycerides-as-a-risk-factor-for-chronic-kidney-disease-in-type-2-diabetes-mellitus-evidence-from-the-northeastern-of-thailand
#7
Sojib Bin Zaman, Mohd Anisul Karim, Naznin Hossain, Gulam Muhammed Al Kibria, Sheikh Mohammed Shariful Islam
AIMS: To investigate the observational association between plasma triglyceride and CKD in patients with T2DM. METHODS: A hospital-based retrospective registry was used to obtain data of 3748 T2DM patients from May 2016 to October 2016. Anthropometric measurements and biochemical reports of T2DM patients with CKD were obtained by data extraction of medical records. CKD was defined according to the estimated glomerular filtration rate (eGFR <60mL/min/1.73 m 2 )...
February 12, 2018: Diabetes Research and Clinical Practice
https://www.readbyqxmd.com/read/29447647/association-of-pemphigus-and-systemic-corticosteroid-use-with-comorbid-health-disorders-a-case-control-study
#8
Derek Y Hsu, Joaquin Brieva, Beatrice Nardone, Dennis West, Jonathan I Silverberg
BACKGROUND: Pemphigus is a group of debilitating autoimmune blistering disorders associated with painful blisters of the skin and/or mucous membranes. Identification and management of the comorbiditiesof pemphigus is critically important to minimize morbidity and decrease mortality. OBJECTIVE: To identify the comorbid health conditions of pemphigus vulgaris. METHODS: This was a case-control study of 130 cases of pemphigus verified by a clinical and laboratory diagnosis and 390 age and sex-matched controls with complete follow-up at a large metropolitanquaternary care medical center...
December 15, 2017: Dermatology Online Journal
https://www.readbyqxmd.com/read/29443460/tracking-the-sugar-rush-incorporating-continuous-glucose-monitoring-into-multisite-early-clinical-research-with-type-2-diabetes-subjects
#9
Sabina Paglialunga, Bruce H Morimoto, Amparo de la Peña, Caroline Fortier
Continuous glucose monitoring (CGM) systems allow patients with diabetes mellitus to closely track glucose concentrations over several days, identify trends in glucose levels, and avoid glucose excursions. This technology has not only advanced diabetes mellitus management but has increased patient safety through greater glycemic awareness. Due to these attributes, CGM is now being applied in therapeutic research as a pharmacodynamic tool to support early clinical drug development programs. However, to date only a handful of studies have utilized CGM in type 2 diabetes mellitus (T2DM) drug development...
February 14, 2018: Clinical Pharmacology in Drug Development
https://www.readbyqxmd.com/read/29430192/the-prevalence-and-determinants-of-poor-glycemic-control-among-adults-with-type-2-diabetes-mellitus-in-saudi-arabia
#10
Riyadh A Alzaheb, Abdullah H Altemani
Background: Although the prevalence of type 2 diabetes mellitus (T2DM) is rising sharply in Saudi Arabia, data on glycemic control, crucial to reducing diabetes mellitus complications, remain scarce. This study therefore investigated glycemic control status and the factors influencing poor glycemic control among adult T2DM patients in Saudi Arabia. Methods: This cross-sectional study examined 423 T2DM patients at a diabetic center in Tabuk, Saudi Arabia between September 2016 and July 2017...
2018: Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy
https://www.readbyqxmd.com/read/29428572/metabolic-control-and-complications-in-italian-people-with-diabetes-treated-with-continuous-subcutaneous-insulin-infusion
#11
Giuseppe Lepore, Riccardo Bonfanti, Lutgarda Bozzetto, Vincenzo Di Blasi, Angela Girelli, Giorgio Grassi, Dario Iafusco, Luigi Laviola, Ivana Rabbone, Riccardo Schiaffini, Daniela Bruttomesso
BACKGROUND AND AIM: The objective of this cross-sectional study was to evaluate the degree of glycaemic control and the frequency of diabetic complications in Italian people with diabetes who were treated with continuous subcutaneous insulin infusion (CSII). METHODS AND RESULTS: Questionnaires investigating the organisation of diabetes care centres, individuals' clinical and metabolic features and pump technology and its management were sent to adult and paediatric diabetes centres that use CSII for treatment in Italy...
December 9, 2017: Nutrition, Metabolism, and Cardiovascular Diseases: NMCD
https://www.readbyqxmd.com/read/29425754/does-the-medical-comorbidity-profile-of-obstructive-sleep-apnea-patients-treated-with-maxillomandibular-advancement-differ-from-that-of-obstructive-sleep-apnea-patients-managed-nonsurgically
#12
Richard Ngo, Elaina Pullano, Zachary S Peacock, Edward T Lahey, Meredith August
PURPOSE: Obstructive sleep apnea (OSA) patients with retrognathia and measurable anatomic airway determinants may represent a subset of OSA patients and have distinct comorbidity profiles. Our aim was to compare the medical comorbidities of OSA patients managed surgically with maxillomandibular advancement with those of nonsurgical patients. PATIENTS AND METHODS: In this cross-sectional retrospective study, patients for both cohorts were identified through the Massachusetts General Hospital oral and maxillofacial surgery data registry and the Massachusetts General Hospital Research Patient Data Registry...
January 31, 2018: Journal of Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/29422746/diabetes-mellitus-type-2-and-yoga-electro-photonic-imaging-perspective
#13
Romesh Kumar Bhat, Ramesh Mavathur, T M Srinivasan
Background: Yoga is the most popular form of alternative medicine for the management of diabetes mellitus type 2. The electro-photonic imaging (EPI) is another contribution from alternative medicine in health monitoring. Aim: To evaluate diabetes from EPI perspective. Objectives: (1) Compare various EPI parameters in normal, prediabetic and diabetic patients. (2) Find difference in controlled and uncontrolled diabetes. (3) Study the effect of 7 days diabetes-specific yoga program...
September 2017: International Journal of Yoga
https://www.readbyqxmd.com/read/29422033/a-case-report-of-tubo-ovarian-abscess-caused-by-burkholderia-pseudomallei
#14
Pattaranit Nernsai, Areepan Sophonsritsuk, Srithean Lertvikool, Artit Jinawath, Maria Nina Chitasombat
BACKGROUND: Melioidosis, the disease caused by Burkholderia pseudomallei is endemic in the Northeastern part of Thailand, South-East Asia, and Northern Australia. The pelvic involvement of disease is rare even in an endemic area. Therefore, we describe in this report the clinical presentation, management, and outcome of the patient with primary tubo-ovarian abscess due to melioidosis. CASE PRESENTATION: A 31-year-old Thai cassava farmer woman presented with fever and abdominal pain at left lower quadrant for one month...
February 8, 2018: BMC Infectious Diseases
https://www.readbyqxmd.com/read/29416318/adherence-to-dietary-recommendations-in-diabetes-mellitus-disease-acceptance-as-a-potential-mediator
#15
Mariusz Jaworski, Mariusz Panczyk, Małgorzata Cedro, Alicja Kucharska
Background: Adherence by diabetic patients to dietary recommendations is important for effective therapy. Considering patients' expectations in case of diet is significant in this regard. The aim of this paper was to analyze the relationship between selected independent variables (eg, regular blood glucose testing) and patients' adherence to dietary recommendations, bearing in mind that the degree of disease acceptance might play a mediation role. Subjects and methods: A cross-sectional study was conducted in 91 patients treated for type 2 diabetes mellitus in a public medical facility...
2018: Patient Preference and Adherence
https://www.readbyqxmd.com/read/29413998/lipid-lowering-treatment-in-peripheral-artery-disease
#16
REVIEW
Niki Katsiki, Athanasios D Giannoukas, Vasilios G Athyros, Dimitri P Mikhailidis
Peripheral artery disease (PAD) is characterized by increased cardiovascular (CV) risk, limb morbidity and all-cause mortality. According to the current guidelines (2016) of the American Heart Association/American College of Cardiology on the management of PAD patients, statin therapy is recommended for PAD patients in order to treat dyslipidemia and reduce CV risk. The present narrative review discusses the use of statins and other lipid-lowering drugs such as ezetimibe, fibrates, niacin, anacetrapib and proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibitors in PAD patients in terms of both CV and limb outcomes...
January 31, 2018: Current Opinion in Pharmacology
https://www.readbyqxmd.com/read/29412115/genetic-variations-and-subclinical-markers-of-carotid-atherosclerosis-in-patients-with-type-2-diabetes-mellitus
#17
Sara Mankoc Ramus, Danijel Petrovic
Atherosclerosis and its cardiovascular complications are the main cause of death in diabetic patients. Patients with diabetes mellitus have a greater than 10-fold risk of cardiovascular disease in their lifetime. The carotid intima-media thickness (cIMT), a surrogate marker for the presence and progression of atherosclerosis, predicts future cardiovascular events in asymptomatic subjects with type 2 diabetes mellitus (T2DM). This review focuses on genetic variants that contribute to the pathobiology of subclinical atherosclerosis in the setting of T2DM...
February 5, 2018: Current Vascular Pharmacology
https://www.readbyqxmd.com/read/29410236/gut-microbiota-and-probiotics-intervention-a-potential-therapeutic-target-for-management-of-cardiometabolic-disorders-and-chronic-kidney-disease
#18
REVIEW
Marinaldo Pacífico Cavalcanti Neto, Jailane de Souza Aquino, Larissa de Fátima Romão da Silva, Ruanniere de Oliveira Silva, Keyth Sulamitta de Lima Guimarães, Yohana de Oliveira, Evandro Leite de Souza, Marciane Magnani, Hubert Vidal, José Luiz de Brito Alves
The gut microbiota plays an important role in host metabolism and its dysregulation have been related to cardiometabolic disorders (CMD), such as type 2 diabetes mellitus (T2D), dyslipidemia and arterial hypertension, as well as to chronic kidney diseases (CKD). The implication of the gut microbiota on systemic disorders has been associated with changes in its composition (dysbiosis) as a result of the oxidative unbalance in the body. This alteration may be the result of the adoption of unhealthy lifestyle behavior, including lack of physical activity and fat- or sugar-rich diets, which are largely associated with increased incidence of CMD and CKD...
February 2, 2018: Pharmacological Research: the Official Journal of the Italian Pharmacological Society
https://www.readbyqxmd.com/read/29407047/heart-failure-epidemiology-pathophysiology-and-management-of-heart-failure-in-diabetes-mellitus
#19
REVIEW
Anders Jorsal, Henrik Wiggers, John J V McMurray
This article briefly discusses the epidemiology of heart failure and diabetes and summarizes the key findings from the recent cardiovascular outcome trials in patients with type 2 diabetes, with a focus on heart failure as an endpoint.
March 2018: Endocrinology and Metabolism Clinics of North America
https://www.readbyqxmd.com/read/29405644/variations-in-subclinical-left-ventricular-dysfunction-functional-capacity-and-clinical-outcomes-in-different-heart-failure-aetiologies
#20
Ying Wang, Hong Yang, Mark Nolan, Faraz Pathan, Kazuaki Negishi, Thomas H Marwick
AIMS: Patients with heart failure (HF) risk factors are described as being in Stage A of this condition (SAHF). Management is directed towards prevention of HF progression, but to date, no evidence has been described to align the intensity of this intervention to HF risk. We sought to what extent SAHF of Type 2 diabetes mellitus (T2DM) and other HF risks showed differences in subclinical left ventricular function, exercise capacity, and prognosis. METHODS AND RESULTS: We recruited 551 elder asymptomatic SAHF patients (age 71 ± 5 years, 49% men, 290 T2DM) with at least one risk factor from a community-based population with preserved ejection fraction...
February 5, 2018: ESC Heart Failure
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