keyword
https://read.qxmd.com/read/38509679/targeting-hypertension-a-review-on-pathophysiological-factors-and-treatment-strategies
#21
JOURNAL ARTICLE
Ruhani Raj, Minakshi Garg, Anupreet Kaur
Hypertension is one of the primary causes of cardiovascular diseases and death, with a higher prevalence in low- and middle-income countries. The pathophysiology of hypertension remains complex, with 2% to 5% of patients having underlying renal or adrenal disorders. The rest are referred to as essential hypertension, with derangements in various physiological mechanisms potentially contributing to the development of essential hypertension. Hypertension elevates the risk of cardiovascular disease (CVD) events (coronary heart disease, heart failure, and stroke) and mortality...
March 20, 2024: Current Hypertension Reviews
https://read.qxmd.com/read/38508649/decentralising-chronic-disease-management-in-sub-saharan-africa-a-protocol-for-the-qualitative-process-evaluation-of-community-based-integrated-management-of-hiv-diabetes-and-hypertension-in-tanzania-and-uganda
#22
JOURNAL ARTICLE
Marie-Claire Van Hout, Mathias Akugizibwe, Elizabeth Henry Shayo, Moreen Namulundu, Francis Xavier Kasujja, Ivan Namakoola, Josephine Birungi, Joseph Okebe, Jamie Murdoch, Sayoki Godfrey Mfinanga, Shabbar Jaffar
INTRODUCTION: Sub-Saharan Africa continues to experience a syndemic of HIV and non-communicable diseases (NCDs). Vertical (stand-alone) HIV programming has provided high-quality care in the region, with almost 80% of people living with HIV in regular care and 90% virally suppressed. While integrated health education and concurrent management of HIV, hypertension and diabetes are being scaled up in clinics, innovative, more efficient and cost-effective interventions that include decentralisation into the community are required to respond to the increased burden of comorbid HIV/NCD disease...
March 20, 2024: BMJ Open
https://read.qxmd.com/read/38506279/usefulness-of-cardiopulmonary-exercise-test-combined-with-exercise-stress-echocardiography-in-mild-chronic-thromboembolic-pulmonary-disease
#23
JOURNAL ARTICLE
Min Sun Kim, Kina Jeon, Eun Kyoung Kim, Taek Kyu Park, Hye Yun Park, Jeong Hoon Yang, Sung-Ji Park, Sang-Chol Lee, Seung Woo Park, Duk-Kyung Kim, Sung-A Chang
PURPOSE: Chronic thromboembolic pulmonary disease (CTEPD) can lead to exercise limitations even without right ventricular (RV) dysfunction or pulmonary hypertension at rest. Combining exercise stress echocardiography with cardiopulmonary exercise testing (ESE-CPET) for RV function and pressure changes combined measuring overall function may be useful for CTEPD evaluation. This study aims to investigate CPET and ESE results to elucidate the mechanisms of exercise limitation in mild CTEPD cases...
March 2024: Echocardiography
https://read.qxmd.com/read/38504197/cavi-cardio-ankle-vascular-index-as-an-independent-predictor-of-hypertensive-response-to-exercise
#24
JOURNAL ARTICLE
C Wuttichaipradit, C Yodwut, P Sukhum, K Hengrussamee, M Treesong, S Thiangtham, B Samut, A Tunhasiriwet, T Yingchoncharoen
OBJECTIVES: Hypertensive response to exercise (HRE) is related to the development of future hypertension, cardiovascular morbidity, and mortality, independent of resting blood pressure. We hypothesized that arterial stiffness as measured by cardio-ankle vascular index (CAVI) could be an independent predictor of HRE. MATERIALS AND METHODS: Retrospective chart review of patients participated in the preventive health program at the Bangkok Heart Hospital who underwent both CAVI and treadmill stress testing on the same day between June and December 2018 were performed...
March 19, 2024: BMC Cardiovascular Disorders
https://read.qxmd.com/read/38501750/association-of-postexercise-blood-pressure-with-cardiovascular-outcomes-and-mortality-the-cardia-study
#25
JOURNAL ARTICLE
Jia-Jie Wang, Zhichao Zheng, Ying Zhang
Postexercise blood pressure (BP) may be a better predictor of cardiovascular risk than office BP, but there is a lack of data supporting this claim. We hypothesized that postexercise BP may be an important prognostic marker. Our aim was to evaluate the association of postexercise BP with major adverse cardiovascular events (MACE) and all-cause mortality. A total of 2581 participants (median age, 46 years; 55.9% women) from the Coronary Artery Risk Development in Young Adults study at year 20 (2005-2006) who underwent a graded exercise treadmill test using a modified Balke graded protocol were included...
March 19, 2024: Journal of Clinical Hypertension
https://read.qxmd.com/read/38500893/escalating-oral-treprostinil-dose-with-intravenous-treprostinil-bridging-therapy
#26
Vanessa C Perez, Veronica Williams, Franck F Rahaghi
Oral treprostinil, approved for the treatment of pulmonary arterial hypertension, remains an attractive option in combination with other medications to delay disease progression and improve exercise capacity. However, patients are often challenged with the ability to overcome adverse effects as outpatients and reach effective doses in a timely manner. We describe a case of a 47-year-old female on oral treprostinil who presented to the clinic with worsening symptoms of disease, necessitating higher dosing. This patient was previously uptitrated outpatient with oral treprostinil, which had allowed her to remain stable for years...
February 2024: Curēus
https://read.qxmd.com/read/38500257/successful-anesthetic-management-for-obese-patients-with-interstitial-lung-disease-undergoing-laparoscopic-sleeve-gastrectomy-a-bridge-to-improved-lung-transplant-eligibility
#27
JOURNAL ARTICLE
Piotr Mieszczański, Marek Janiak, Paweł Ziemiański, Radosław Cylke, Wojciech Lisik, Janusz Trzebicki
BACKGROUND Patients with obesity with interstitial lung diseases (ILD) are encouraged to lose weight, as it improves lung function and lung transplant eligibility. As exercise tolerance in these patients is low and weight gain is a common adverse effect of corticosteroids, bariatric surgery can be an effective method for the management of obesity in this patient group. However, perioperative complications in such high-risk patients remain a concern. Therefore, we aimed to demonstrate successful anesthetic management for obese patients with ILD, which may be practically utilized to reduce perioperative pulmonary complications and improve outcomes...
March 19, 2024: American Journal of Case Reports
https://read.qxmd.com/read/38500081/management-of-kidney-transplant-recipients-for-primary-care-practitioners
#28
REVIEW
Manal Alotaibi, Brandon Trollinger, Sam Kant
Patients with kidney transplants have a significant co-morbidity index, due to a high number of pre-existing conditions and use of immunosuppression medications. These patients are at higher risk of developing conditions such as hypertension, dyslipidemia, post-transplant diabetes, cardiovascular events, and anemia. Moreover, they are particularly susceptible to infections such as urinary tract infections or pyelonephritis, cancers, and gastrointestinal complications such as diarrhea, which in turn may be attributed to medication adverse effects or infectious causes...
March 18, 2024: BMC Nephrology
https://read.qxmd.com/read/38497804/feasible-and-safe-approaches-for-exercise-adherence-in-hypertension
#29
JOURNAL ARTICLE
Maycon Junior Ferreira, Emerson Sebastião, Paulo Henrique Silva Pelicioni
No abstract text is available yet for this article.
March 18, 2024: American Journal of Hypertension
https://read.qxmd.com/read/38496326/accuracy-of-apple-watch-to-measure-cardiovascular-indices-in-patients-with-chronic-diseases-a-cross-sectional-study
#30
JOURNAL ARTICLE
Alaa Abdulhafiz Khushhal, Ashraf Abdelaal Mohamed, Mahmoud Elshahat Elsayed
BACKGROUND: The validity of the Apple Watch to measure the heart rate (HR) and oxygen saturation (Spo2 ) for patients with chronic diseases such as diabetes mellitus (DM), dyslipidemia, and hypertension is still unclear. Therefore, this study aims to investigate the accuracy of the Apple Watch in measuring the Spo2 and HR in patients with chronic diseases. METHODS: Forty-one patients with chronic diseases, including 20 with hypertension, 10 with diabetes, and 11 with dyslipidemia, completed a cross-sectional study...
2024: Journal of Multidisciplinary Healthcare
https://read.qxmd.com/read/38495825/exercise-training-affects-calcium-ion-transport-by-downregulating-the-cacna2d1-protein-to-reduce-hypertension-induced-myocardial-injury-in-mice
#31
JOURNAL ARTICLE
Shan Gao, Wei Yao, Rui Zhou, Zuowei Pei
Hypertension is a risk factor for cardiovascular disease, and exercise has cardioprotective effects on the heart. However, the mechanism by which exercise affects hypertension-induced myocardial injury remains unclear. Exercise response model of hypertension-induced myocardial injury in mice was analyzed using multiomics data to identify potential factors. The study found that serum Ca2+ and brain natriuretic peptide concentrations were significantly higher in the HTN (hypertension) group than in the control, HTN+MICT (moderate intensity continuous exercise), and HTN+HIIT (high intensity intermittent exercise) groups...
April 19, 2024: IScience
https://read.qxmd.com/read/38495758/the-impact-of-sprint-interval-training-versus-moderate-intensity-continuous-training-on-blood-pressure-and-cardiorespiratory-health-in-adults-a-systematic-review-and-meta-analysis
#32
JOURNAL ARTICLE
Weibao Liang, Chuannan Liu, Xujie Yan, Yu Hou, Guan Yang, Jianmin Dai, Songtao Wang
BACKGROUND: Although aerobic exercise is the primary modality recommended for the treatment of hypertension, it remains unclear whether high-intensity all-out sprint interval training (SIT) can result in greater reductions of blood pressure (BP) and cardiorespiratory health. This systematic review aims to compare the impact of SIT versus Moderate-intensity continuous training (MICT) on improvements in resting systolic blood pressure (SBP), diastolic blood pressure (DBP) and maximal oxygen uptake (VO2 max) among adults...
2024: PeerJ
https://read.qxmd.com/read/38493884/hemodynamic-ventilatory-and-gas-exchange-responses-to-exercise-using-a-cycle-ergometer-and-the-incremental-shuttle-walk-test-in-pregnant-women
#33
JOURNAL ARTICLE
A T Dennis, E Traer, H Ismail, B J Riedel
BACKGROUND: Cardiovascular disease, including hypertension, in pregnant women is a leading cause of morbidity and mortality globally. The development of reference intervals for cardiovascular responses using exercising testing to measure oxygen utilisation (V̇O2 ) with cardiopulmonary exercise testing (CPET), and distances walked using the incremental shuttle walk test (ISWT), may be promising methods to assess and stratify pregnant women regarding their risk of adverse pregnancy outcomes, to encourage exercise during pregnancy, and to improve exercise prescriptions during pregnancy...
March 15, 2024: American Heart Journal
https://read.qxmd.com/read/38487358/the-impact-of-valsalva-manoeuvres-and-exercise-on-intracranial-pressure-and-cerebrovascular-dynamics-in-idiopathic-intracranial-hypertension
#34
JOURNAL ARTICLE
Andreas Yiangou, Samuel R C Weaver, Mark Thaller, James L Mitchell, Hannah S Lyons, Georgios Tsermoulas, Susan P Mollan, Samuel J E Lucas, Alexandra J Sinclair
Idiopathic intracranial hypertension (IIH) is a disease characterised by elevated intracranial pressure (ICP). The impact of straining and exercise on ICP regulation is poorly understood yet clinically relevant to IIH patient care. We sought to investigate the impact of Valsalva manoeuvres (VMs) and exercise on ICP and cerebrovascular haemodynamics in IIH. People with IIH were prospectively enrolled and had an intraparenchymal telemetric ICP sensor inserted. Three participants (age [mean ± standard deviation]: 40...
2024: Neuro-ophthalmology
https://read.qxmd.com/read/38483844/effects-of-telerehabilitation-on-cardiac-remodeling-and-hemodynamics-parameters-in-hypertensive-older-adults-a-randomized-controlled-trial
#35
JOURNAL ARTICLE
Anderson Jm Rodrigues-da-Silva, Jennifer As Suassuna, Eduardo Dos Ss Monteiro, Isabelle A Borges de Lima, Amilton da Cruz Santos, Maria do Socorro Brasileiro-Santos
OBJECTIVE: This study aimed to assess the effects of telerehabilitation with multimodal exercise on cardiac remodeling and blood pressure in hypertensive older adults. METHODS: Thirty-two hypertensive older adults (66.7 ± 5.33 years; 29.5 ± 4.22 Kg/m2 ; 24 female) were randomized into either a telerehabilitation or a control group. Echocardiographic parameters and blood pressure were assessed before and after the 16-week intervention...
March 14, 2024: Journal of Telemedicine and Telecare
https://read.qxmd.com/read/38481952/effects-of-different-traditional-chinese-exercise-in-the-treatment-of-essential-hypertension-a-systematic-review-and-network-meta-analysis
#36
REVIEW
Qingyuan Zhang, Xiaogang Xu, Qianyan Wu, Jingwen Zhang, Shenghe Huang, Lin Wu, Minping Tian, Delin Zhang
BACKGROUND: As a therapy to prevent and treat essential hypertension (EH), traditional Chinese exercises (TCEs) were widely used in clinical practice. However, there is a lack of strictly comparison of the antihypertensive efficacy of different TCEs, which not conducive to the selection of the best and most optimal treatment. This study aimed to perform a network meta-analysis to objectively evaluate which TCE has the best effects in assisting with lowering blood pressure. METHODS: PubMed, Embase, the Cochrane Library, Chinese National Knowledge Infrastructure (CNKI), VIP, SinoMed and Wanfang Data were searched for all randomized controlled trials (RCTs) on TCEs for the treatment of EH published up to July 10, 2023...
2024: Frontiers in Cardiovascular Medicine
https://read.qxmd.com/read/38481900/obstructive-sleep-apnea-syndrome-in-heavy-truck-drivers-a-portuguese-prospective-cohort-study
#37
JOURNAL ARTICLE
Cátia Pimentel, Diana Amorim, Cláudia Santos, Ana Macedo, Salvato Feijó
INTRODUCTION: Heavy truck drivers with untreated obstructive sleep apnea (OSA) are at higher risk of driving accidents. This study aims to estimate the prevalence of OSA and to identify the most frequent symptoms and comorbidities in heavy truck drivers. METHODS: This cohort study included the employees of a Portuguese transport company between 2019 and 2022. A home sleep apnea test (HSAT) was performed on all patients. SPSS® was used for statistical analysis, and a p-value lower than 0...
February 2024: Curēus
https://read.qxmd.com/read/38471134/chronic-exercise-improves-renal-at-1-and-etb-receptor-functions-via-modulating-grk4-expression-in-obese-zucker-rats
#38
JOURNAL ARTICLE
Jingjing Lu, Zhengsheng Li, Yinan Yang, Fangning Wei
BACKGROUND: Physical activity has profound benefits on health, especially in patients with cardiovascular and metabolic disease. Exercise training can reduce oxidative stress, improve renal function, and thus lower blood pressure. However, the effect of exercise training on angiotensin II type 1 receptors (AT1 R) and endothelin subtype B receptors (ETBR)-mediated diuresis and natriuresis in obese Zucker rats is unclear. METHODS: Lean and obese Zucker rats were exercised or placed on a nonmoving treadmill for 8 weeks...
December 31, 2024: Clinical and Experimental Hypertension: CHE
https://read.qxmd.com/read/38468630/evaluating-the-efficacy-and-safety-of-oral-triple-sequential-combination-therapy-for-treating-patients-with-pulmonary-arterial-hypertension-a-multicenter-retrospective-study
#39
JOURNAL ARTICLE
Qin-Hua Zhao, Jun Chen, Fa-Dong Chen, Hong-Yun Ruan, Wei Zhang, Yan-Li Zhou, Qi-Qi Wang, Xiao-Ling Xu, Ke-Fu Feng, Jian-Zhou Guo, Su-Gang Gong, Rui-Feng Zhang, Lan Wang
This study aimed to evaluate the effectiveness and safety of an oral sequential triple combination therapy with selexipag after dual combination therapy with endothelin receptor antagonist (ERA) and phosphodiesterase-5 inhibitor (PDE5I)/riociguat in pulmonary arterial hypertension (PAH) patients. A total of 192 PAH patients from 10 centers had received oral sequential selexipag therapy after being on dual-combination therapy with ERA and PDE5i/riociguat for a minimum of 3 months. Clinical data were collected at baseline and after 6 months of treatment...
January 2024: Pulmonary Circulation
https://read.qxmd.com/read/38465629/association-of-childhood-socioeconomic-status-with-adulthood-maximal-exercise-blood-pressure-the-cardiovascular-risk-in-young-finns-study
#40
JOURNAL ARTICLE
Erika Kähönen, Emilia Kähönen, Kristiina Pälve, Janne Hulkkonen, Mika Kähönen, Olli T Raitakari, Nina Hutri, Terho Lehtimäki, Heikki Aatola
PURPOSE: Socioeconomic status has been related to resting blood pressure (BP) levels at different stages of life. However, the association of childhood socioeconomic status (SES) and adulthood exercise BP is largely unknown. Therefore, we studied the association of childhood SES with adulthood maximal exercise BP. MATERIALS AND METHODS: This investigation consisted of 373 individuals (53% women) participating in the Cardiovascular Risk in Young Finns Study who had data concerning family SES in childhood (baseline in 1980, at age of 6-18 years) and exercise BP response data in adulthood (follow-up in adulthood in 27-29 years since baseline)...
December 2024: Blood Pressure
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