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https://www.readbyqxmd.com/read/29684784/pilot-scale-outdoor-production-of-scenedesmus-sp-in-raceways-using-flue-gases-and-centrate-from-anaerobic-digestion-as-the-sole-culture-medium
#1
Ahlem Jebali, F Gabriel Acién, Erika Rodriguez Barradas, Eugenia J Olguín, Sami Sayadi, Emilio Molina Grima
This work investigated the production of Scenedesmus sp. in semi-continuous mode in three pilot-scale outdoor raceways (7.2 m2 ) using flue gas for CO2 supply and centrate from the anaerobic digestion of urban wastewater as the sole nutrient source. Experiments were performed at different culture depths, 5, 10 and 15 cm, while evaluating two centrate concentrations (30% and 45%) at dilution rates of 0.2 and 0.3 d-1 . Under optimal conditions of 30% centrate, 0.3 d-1 dilution rate and a 15 cm culture depth, a maximum biomass productivity of 22...
April 17, 2018: Bioresource Technology
https://www.readbyqxmd.com/read/29684743/neuroendocrine-neoplasms-of-rectum-a-management-update
#2
REVIEW
Emilio Bertani, Davide Ravizza, Massimo Milione, Sara Massironi, Chiara Maria Grana, Dario Zerini, Alessandra Nella Piccioli, Giuseppe Spinoglio, Nicola Fazio
The estimated annual incidence of R-NENs is 1.04 per 100,000 persons although the real incidence may be underestimated, as not all R-NEN are systematically reported in registers. Also the prevalence has increased substantially, reflecting the rising incidence and indolent nature of R-NENs, showing the highest prevalence increase among all site of origin of NENs. The size of the tumor reveals the behavior of R-NENs where the risk for metastatic spread increases for lesions > 10 mm. Applying the WHO 2010 grading system to whole NENs originating in the gastroenteropancreatic system, R-NENs are classified as Well-Differentiated Neuroendocrine Tumors (WD-NET), which contain NET G1 and NET G2, and Poorly-Differentiated Carcinomas (PD-NEC) enclosing only G3 neoplasms for which the term carcinoma is applied...
April 6, 2018: Cancer Treatment Reviews
https://www.readbyqxmd.com/read/29684480/fetuin-b-links-vitamin-d-deficiency-and-pediatric-obesity-direct-negative-regulation-by-vitamin-d
#3
Gillian E Walker, Antonia Follenzi, Valentina Bruscaggin, Marcello Manfredi, Simonetta Bellone, Emilio Marengo, Luigi Maiuri, Flavia Prodam, Gianni Bona
Vitamin D (VD) deficiency (VDD) correlates to obesity, with VD a recognized mediator of metabolic diseases. From a previous proteomic study identifying adiponectin as a link between VDD and pediatric obesity, herein we analysed another protein (SSP2301) increased with VDD. A focused 2D-electrophoretic analysis identified 4 corresponding plasma proteins, with one predicted to be fetuin B (FETUB). FETUB was studied due to its emerging role in metabolic diseases and cytogenetic location (3q27.3) with adiponectin...
April 20, 2018: Journal of Steroid Biochemistry and Molecular Biology
https://www.readbyqxmd.com/read/29684072/arginine-is-a-component-of-the-ammonium-cyg56-signalling-cascade-that-represses-genes-of-the-nitrogen-assimilation-pathway-in-chlamydomonas-reinhardtii
#4
David González-Ballester, Emanuel Sanz-Luque, Aurora Galván, Emilio Fernández, Amaury de Montaigu
Nitrogen assimilation and metabolism are essential processes for all living organisms, yet there is still much to be learnt on how they are regulated. The use of Chlamydomonas reinhardtii as a model system has been instrumental not only in identifying conserved regulation mechanisms that control the nitrogen assimilation pathway, but also in understanding how the intracellular nitrogen status regulates metabolic processes of industrial interest such as the synthesis of biolipids. While the genetic regulators that control the nitrogen pathway are successfully being unravelled, other layers of regulation have received less attention...
2018: PloS One
https://www.readbyqxmd.com/read/29683156/protein-capped-nanosilver-free-radical-oxidation-role-of-biomolecule-capping-on-nanoparticle-colloidal-stability-and-protein-oxidation
#5
Manuel Ahumada, Cornelia Bohne, Jessy Oake, Emilio I Alarcon
We studied the effect of human serum albumin protein capped spherical nanosilver on the nanoparticle stability upon peroxyl radical oxidation. The nanoparticle-protein composite is less prone to oxidation compared to the individual components. However, higher concentrations of hydrogen peroxide were formed in the nanoparticle-protein system.
April 23, 2018: Chemical Communications: Chem Comm
https://www.readbyqxmd.com/read/29682162/metabolic-alterations-in-a-slow-paced-model-of-pancreatic-cancer-induced-wasting
#6
Elisabeth Wyart, Simone Reano, Myriam Y Hsu, Dario Livio Longo, Mingchuan Li, Emilio Hirsch, Nicoletta Filigheddu, Alessandra Ghigo, Chiara Riganti, Paolo Ettore Porporato
Cancer cachexia is a devastating syndrome occurring in the majority of terminally ill cancer patients. Notably, skeletal muscle atrophy is a consistent feature affecting the quality of life and prognosis. To date, limited therapeutic options are available, and research in the field is hampered by the lack of satisfactory models to study the complexity of wasting in cachexia-inducing tumors, such as pancreatic cancer. Moreover, currently used in vivo models are characterized by an explosive cachexia with a lethal wasting within few days, while pancreatic cancer patients might experience alterations long before the onset of overt wasting...
2018: Oxidative Medicine and Cellular Longevity
https://www.readbyqxmd.com/read/29681756/repressed-expression-of-a-gene-for-a-basic-helix-loop-helix-protein-causes-a-white-flower-phenotype-in-carnation
#7
Akane Totsuka, Emi Okamoto, Taira Miyahara, Takanobu Kouno, Emilio A Cano, Nobuhiro Sasaki, Aiko Watanabe, Keisuke Tasaki, Masahiro Nishihara, Yoshihiro Ozeki
In a previous study, two genes responsible for white flower phenotypes in carnation were identified. These genes encoded enzymes involved in anthocyanin synthesis, namely, flavanone 3-hydroxylase (F3H) and dihydroflavonol 4-reductase (DFR), and showed reduced expression in the white flower phenotypes. Here, we identify another candidate gene for white phenotype in carnation flowers using an RNA-seq analysis followed by RT-PCR. This candidate gene encodes a transcriptional regulatory factor of the basic helix-loop-helix (bHLH) type...
January 2018: Breeding Science
https://www.readbyqxmd.com/read/29681641/new-subtype-of-familial-achondrogenesis-type-ia-houston-harris
#8
Sergio Alberto Ramírez-García, Diana García-Cruz, Iván Cervantes-Aragón, Wadih Emilio Bitar-Alatorre, Ingrid Patricia Dávalos-Rodríguez, Nory Omayra Dávalos-Rodríguez, Jorge Román Corona-Rivera, José Sánchez-Corona
Background: Achondrogenesis is a skeletal dysplasia characterized primarily by short stature, severe micromelia, short and narrow chest, prematurity, polyhydramnios, fetal hydrops, and in utero or neonatal death. Based on the radiological and histopathological findings, there are three types of achondrogenesis: type 1A (Houston-Harris), type 1B (Fraccaro) and type 2 (Langer-Saldino). Clinical case: A premature female product was studied whose clinical, radiological and histopathological characteristics were compatible with achondrogenesis Type 1A...
2018: Cirugia y Cirujanos
https://www.readbyqxmd.com/read/29681636/parkinsonism-as-presenting-symptom-of-primary-hyperparathyroidism-improvement-after-surgery
#9
Delia Luján-Martínez, Ángela Sánchez-Cifuentes, Emilio Peña-Ros, Antonio Albarracín-Marín-Blázquez, Mari Fe Candel-Arenas
Introduction: Hypercalcemia can cause different neurological disorders, depending on the calcium level. We report an exceptional case of primary hyperparathyroidism presenting as neurological alteration and it has favourable outcome after parathyroidectomy. Case report: A 74-year-old woman presented with progressive cognitive deterioration and impaired motor function. The complementary tests showed hypercalcemia due to a parathyroid adenoma. Parathyroidectomy was performed with symptomatic improvement...
2018: Cirugia y Cirujanos
https://www.readbyqxmd.com/read/29681545/nf-%C3%AE%C2%BAb-activity-initiates-human-esc-derived-neural-progenitor-cell-differentiation-by-inducing-a-metabolic-maturation-program
#10
Lorna M FitzPatrick, Kate E Hawkins, Juliette M K M Delhove, Emilio Fernandez, Chiara Soldati, Louise F Bullen, Axel Nohturfft, Simon N Waddington, Diego L Medina, Juan P Bolaños, Tristan R McKay
Human neural development begins at embryonic day 19 and marks the beginning of organogenesis. Neural stem cells in the neural tube undergo profound functional, morphological, and metabolic changes during neural specification, coordinated by a combination of exogenous and endogenous cues. The temporal cell signaling activities that mediate this process, during development and in the postnatal brain, are incompletely understood. We have applied gene expression studies and transcription factor-activated reporter lentiviruses during in vitro neural specification of human pluripotent stem cells...
April 17, 2018: Stem Cell Reports
https://www.readbyqxmd.com/read/29680909/employment-support-needs-of-people-with-schizophrenia-a-scoping-study
#11
REVIEW
Viviana R Carmona, Juana Gómez-Benito, J Emilio Rojo-Rodes
Purpose People with schizophrenia continue to encounter barriers to employment acquisition. The aim of this scoping study was to identify and synthesize existent evidence about the employment support needs of people diagnosed with schizophrenia. Methods Five relevant databases were used: CINAHL, Medline, PsycINFO, SCOPUS, and Web of Science. Additional material of potential interest was identified through the references of the retrieved articles. A manual search for publications from the 3 months immediately prior to the electronic search was carried out in specialized journals...
April 21, 2018: Journal of Occupational Rehabilitation
https://www.readbyqxmd.com/read/29680205/comparative-risk-of-major-congenital-malformations-with-eight-different-antiepileptic-drugs-a-prospective-cohort-study-of-the-eurap-registry
#12
Torbjörn Tomson, Dina Battino, Erminio Bonizzoni, John Craig, Dick Lindhout, Emilio Perucca, Anne Sabers, Sanjeev V Thomas, Frank Vajda
BACKGROUND: Evidence for the comparative teratogenic risk of antiepileptic drugs is insufficient, particularly in relation to the dosage used. Therefore, we aimed to compare the occurrence of major congenital malformations following prenatal exposure to the eight most commonly used antiepileptic drugs in monotherapy. METHODS: We did a longitudinal, prospective cohort study based on the EURAP international registry. We included data from pregnancies in women who were exposed to antiepileptic drug monotherapy at conception, prospectively identified from 42 countries contributing to EURAP...
April 18, 2018: Lancet Neurology
https://www.readbyqxmd.com/read/29680059/storage-stability-and-composition-changes-of-three-cold-pressed-nut-oils-under-refrigeration-and-room-temperature-conditions
#13
Adrián Rabadán, Manuel Álvarez-Ortí, José Emilio Pardo, Andrés Alvarruiz
Chemical composition and stability parameters of three cold-pressed nut oils (almond, walnut and pistachio) were monitored for up to 16 months of storage at 5 °C, 10 °C, 20 °C and room temperature. Freshly pressed pistachio oil had lower peroxide value than almond oil and higher induction period than almond and walnut oils, indicating a higher stability. The peroxide values increased faster at room temperature than at lower temperatures during the storage time, and the highest increase was for pistachio oil stored at room temperature exposed to daylight...
September 1, 2018: Food Chemistry
https://www.readbyqxmd.com/read/29676408/response-to-comment-on-new-alternatives-for-autoimmune-disease-treatments-physicochemical-and-clinical-comparability-of-biosimilar-etanercept
#14
COMMENT
Mariana P Miranda-Hernández, Carlos A López-Morales, Francisco C Perdomo-Abúndez, Rodolfo D Salazar-Flores, Nancy D Ramírez-Ibanez, Nestor O Pérez, Aaron Molina-Pérez, Jorge Revilla-Beltri, Emilio Medina-Rivero, Luis F Flores-Ortiz
No abstract text is available yet for this article.
2018: Journal of Immunology Research
https://www.readbyqxmd.com/read/29675558/dietary-polyunsaturated-fatty-acids-mediate-the-inverse-association-of-stearoyl-coa-desaturase-activity-with-the-risk-of-fatty-liver-in-dyslipidaemic-individuals
#15
Antonio J Amor, Montserrat Cofán, Rocío Mateo-Gallego, Ana Cenarro, Fernando Civeira, Emilio Ortega, Emilio Ros, Aleix Sala-Vila
PURPOSE: The activity of stearoyl-CoA desaturase-1 (SCD1) is increased in non-alcoholic fatty liver disease (NAFLD). Polyunsaturated fatty acids (PUFA) inhibit SCD1, but clinical studies on whether all dietary PUFA species are equal in SCD1 inhibition are scarce. Serum phospholipids are an objective proxy of dietary intake of plant-derived PUFA (C18:2n-6, C18:3n-3) and marine-derived PUFA (C20:5n-3, C22:6n-3). In 355 participants with primary dyslipidemia, we cross-sectionally investigated whether the presumed association between surrogate markers of NAFLD and SCD1 activity is mediated by intake of PUFA, and, if it is, what PUFA species are relevant in this regard...
April 19, 2018: European Journal of Nutrition
https://www.readbyqxmd.com/read/29674263/electro-fenton-process-for-implementation-of-acid-black-liquor-waste-treatment
#16
Gabriel Buftia, Emilio Rosales, Marta Pazos, Gabriel Lazar, María Angeles Sanromán
In this work, an eco-friendly solution for the remediation of wastewater generated in the lignin recovery process from eco-industrial paper mill has been proposed in their way towards a more circular economy strategy. Thus, the application of the electro-Fenton process for the degradation of the non-recovered lignin and other organic compounds form a scarcely studied acid black liquor waste (ABLW) was successfully performed. This treatment was able to operate in a range of COD loads (0.5-19.5mgO2 ·L-1 ) showing high degradation values of the ABLW determined by the abatement of color, total phenolic content and COD...
April 16, 2018: Science of the Total Environment
https://www.readbyqxmd.com/read/29673806/the-challenges-of-bacillus-of-calmette-guerin-bcg-therapy-for-high-risk-non-muscle-invasive-bladder-cancer-treatment-in-older-patients
#17
Marco Racioppi, Luca Di Gianfrancesco, Mauro Ragonese, Giuseppe Palermo, Emilio Sacco, PierFrancesco Bassi
OBJECTIVES: To evaluate the efficacy and safety of a tailored endovesical immunotherapy protocol with biweekly BCG for elderly Patients with high risk non muscle invasive bladder cancer (HG-NMIBC). MATERIALS AND METHODS: We retrospectively evaluated data from 200 patients older than 80 years newly diagnosed with HG-NMIBC: 100 (group 1) with multiple comorbidities (WHO PS 2-3, ASA score ≥3, Charlson Comorbidity index ≥3, GFR<60 mL/min) were treated with BCG induction course administered biweekly; 100 (group 2) with statistically significant better conditions were treated with standard weekly BCG therapy...
April 16, 2018: Journal of Geriatric Oncology
https://www.readbyqxmd.com/read/29673340/active-commuting-to-and-from-university-obesity-and-metabolic-syndrome-among-colombian-university-students
#18
Antonio García-Hermoso, Andrea P Quintero, Enrique Hernández, Jorge Enrique Correa-Bautista, Mikel Izquierdo, Alejandra Tordecilla-Sanders, Daniel Prieto-Benavides, Carolina Sandoval-Cuellar, Katherine González-Ruíz, Emilio Villa-González, Robinson Ramírez-Vélez
BACKGROUND: There is limited evidence concerning how active commuting (AC) is associated with health benefits in young. The aim of the study was to analyze the relationship between AC to and from campus (walking) and obesity and metabolic syndrome (MetS) in a sample of Colombian university students. METHODS: A total of 784 university students (78.6% women, mean age = 20.1 ± 2.6 years old) participated in the study. The exposure variable was categorized into AC (active walker to campus) and non-AC (non/infrequent active walker to campus: car, motorcycle, or bus) to and from the university on a typical day...
April 19, 2018: BMC Public Health
https://www.readbyqxmd.com/read/29670896/short-term-treatment-with-esmolol-reverses-left-ventricular-hypertrophy-in-adult-spontaneously-hypertensive-rats-via-inhibition-of-akt-nf-%C3%AE%C2%BA-b-and-nfatc4
#19
Begoña Quintana-Villamandos, David A Goukassian, Sharath P Sasi, Emilio Delgado-Baeza
Our group has previously demonstrated that short-term treatment with esmolol reduces left ventricular hypertrophy (LVH) in spontaneously hypertensive rats (SHRs). The present study aimed to assess the molecular mechanisms related to this effect. Fourteen-month-old male SHRs were treated intravenously with saline as vehicle (SHR) or esmolol (SHR-E) (300  μ g/kg/min). Age-matched vehicle-treated male Wistar-Kyoto (WKY) rats served as controls. After 48 hours of treatment, the hearts were harvested and left ventricular tissue was separated and processed for Western blot analysis to determine the levels of Akt, NF- κ B, NFATc4, Creb1, Serca2a, Erk1/2, and Sapk/Jnk...
2018: BioMed Research International
https://www.readbyqxmd.com/read/29670892/bulbar-impairment-score-and-survival-of-stable-amyotrophic-lateral-sclerosis-patients-after-noninvasive-ventilation-initiation
#20
Jesús Sancho, Daniel Martínez, Enric Bures, José Luis Díaz, Alejandro Ponz, Emilio Servera
There is general agreement that noninvasive ventilation (NIV) prolongs survival in amyotrophic lateral sclerosis (ALS) and that the main cause of NIV failure is the severity of bulbar dysfunction. However, there is no evidence that bulbar impairment is a contraindication for NIV. The aim of this study was to determine the effect of bulbar impairment on survival in ALS patients with NIV. ALS patients for whom NIV was indicated were included. Those patients who refused NIV were taken as the control group. 120 patients who underwent NIV and 20 who refused NIV were included...
April 2018: ERJ Open Research
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