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https://www.readbyqxmd.com/read/28937984/evidence-of-complex-contagion-of-information-in-social-media-an-experiment-using-twitter-bots
#1
Bjarke Mønsted, Piotr Sapieżyński, Emilio Ferrara, Sune Lehmann
It has recently become possible to study the dynamics of information diffusion in techno-social systems at scale, due to the emergence of online platforms, such as Twitter, with millions of users. One question that systematically recurs is whether information spreads according to simple or complex dynamics: does each exposure to a piece of information have an independent probability of a user adopting it (simple contagion), or does this probability depend instead on the number of sources of exposure, increasing above some threshold (complex contagion)? Most studies to date are observational and, therefore, unable to disentangle the effects of confounding factors such as social reinforcement, homophily, limited attention, or network community structure...
2017: PloS One
https://www.readbyqxmd.com/read/28936987/characterization-of-highly-crystalline-lead-iodide-nanosheets-prepared-by-room-temperature-solution-processing
#2
Riccardo Frisenda, Joshua O Island, Jose Lado, Emerson Giovanelli, Patricia Gant, Philipp Nagler, Sebastian Bange, John Lupton, Christian Schüller, Aday Molina-Mendoza, Lucia Aballe, Michael Foerster, Tobias Korn, Miguel A Nino, David Perez de Lara, Emilio M Perez, Joaquin Fernandez-Rossier, Andres Castellanos-Gomez
Two-dimensional semiconducting materials are particularly appealing for many applications. Although theory predicts a large number of two-dimensional materials, experimentally only a few of these materials have been identified and characterized comprehensively in the ultrathin limit. Lead iodide, which belongs to the transition metal halides family and has a direct bandgap in the visible spectrum, has been known for a long time and has been well characterized in its bulk form. Nevertheless, studies of this material in the nanometer thickness regime are rather scarce...
September 22, 2017: Nanotechnology
https://www.readbyqxmd.com/read/28935954/process-signatures-in-glatiramer-acetate-synthesis-structural-and-functional-relationships
#3
Víctor R Campos-García, Daniel Herrera-Fernández, Carlos E Espinosa-de la Garza, German González, Luis Vallejo-Castillo, Sandra Avila, Leslie Muñoz-García, Emilio Medina-Rivero, Néstor O Pérez, Isabel Gracia-Mora, Sonia Mayra Pérez-Tapia, Rodolfo Salazar-Ceballos, Lenin Pavón, Luis F Flores-Ortiz
Glatiramer Acetate (GA) is an immunomodulatory medicine approved for the treatment of multiple sclerosis, whose mechanisms of action are yet to be fully elucidated. GA is comprised of a complex mixture of polypeptides with different amino acid sequences and structures. The lack of sensible information about physicochemical characteristics of GA has contributed to its comprehensiveness complexity. Consequently, an unambiguous determination of distinctive attributes that define GA is of highest relevance towards dissecting its identity...
September 21, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28934973/liver-chemistry-in-new-onset-henoch-sch%C3%A3-nlein-syndrome
#4
Giulia Rosti, Gregorio P Milani, Emanuela A Laicini, Emilio F Fossali, Mario G Bianchetti
BACKGROUND: Henoch-Schönlein syndrome is a systemic small-vessel leukocytoclastic vasculitis that usually present with cutaneous, gastrointestinal, articular and renal manifestations. Little is known on liver involvement in this syndrome. This study investigated liver chemistry and creatine kinase in Henoch-Schönlein children. CASE PRESENTATION: Alanine aminotransferase, aspartate aminotransferase, γ-glutamyltransferase, lactate dehydrogenase, total bilirubin, prothrombin time and creatine kinase were assessed in 75 consecutive pediatric patients (41 boys and 34 girls aged from 2...
September 21, 2017: Italian Journal of Pediatrics
https://www.readbyqxmd.com/read/28934516/large-scale-analysis-evaluating-regional-variability-in-the-request-of-laboratory-tests-in-primary-care-and-its-potential-economic-impact
#5
Maria Salinas, Maite López-Garrigós, Emilio Flores, Carlos Leiva-Salinas
Objective: To compare the ratios of requests of aspartate aminotransferase (AST) to alanine aminotransferase (ALT) and urea to creatinine (Crea); to investigate the variability among regions and to calculate the potential savings if a target is reached. Methods: Laboratories were invited to fill out a registration form on the number of AST, ALT, Urea and Crea requested in 2014, and to provide the reagent price of urea and AST. AST:ALT and Urea:Crea were calculated and compared; also compared were potential savings if each laboratory would have reached the target...
August 1, 2017: Laboratory Medicine
https://www.readbyqxmd.com/read/28934240/microbial-characterization-of-bee-pollen-from-the-vesuvius-area-collected-by-using-three-different-traps
#6
Gianluigi Mauriello, Annachiara De Prisco, Gennaro Di Prisco, Antonietta La Storia, Emilio Caprio
Flower pollen is collected by honeybee foragers, adhered on their rear legs and transported into the hives in the form of pellets. Once in the hives, bee pollen is moisturised with nectar and bee mouth secretions and due to enzymatically modifications it becomes the so-called bee-bread, the protein reservoir of young bees. Bee pollen can be artificially removed from bee legs and collected by using specific systems, the bee pollen traps. Bee pollen is commercialized for human consumption as fresh product and after freezing or drying...
2017: PloS One
https://www.readbyqxmd.com/read/28934175/the-role-of-body-adiposity-index-in-determining-body-fat-percentage-in-colombian-adults-with-overweight-or-obesity
#7
Robinson Ramírez-Vélez, Jorge Enrique Correa-Bautista, Katherine González-Ruíz, Alejandra Tordecilla-Sanders, Antonio García-Hermoso, Jacqueline Schmidt-RioValle, Emilio González-Jiménez
The aim of this study is to investigate the accuracy of body adiposity index (BAI) as a convenient tool for assessing body fat percentage (BF%) in a sample of adults with overweight/obesity using bioelectrical impedance analysis (BIA). The study population was composed of 96 volunteers (60% female, mean age 40.6 ± 7.5 years old). Anthropometric characteristics (body mass index, height, waist-to-height ratio, hip and waist circumference), socioeconomic status, and diet were assessed, and BF% was measured by BIA-BF% and by BAI-BF%...
September 21, 2017: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/28932931/usefulness-of-zebrafish-larvae-to-evaluate-drug-induced-functional-and-morphological-renal-tubular-alterations
#8
Rita Gorgulho, Raquel Jacinto, Susana S Lopes, Sofia A Pereira, Erin M Tranfield, Gabriel G Martins, Emilio J Gualda, Rico J E Derks, Ana C Correia, Evelyne Steenvoorden, Petra Pintado, Oleg A Mayboroda, Emilia C Monteiro, Judit Morello
Prediction and management of drug-induced renal injury (DIRI) rely on the knowledge of the mechanisms of drug insult and on the availability of appropriate animal models to explore it. Zebrafish (Danio rerio) offers unique advantages for assessing DIRI because the larval pronephric kidney has a high homology with its human counterpart and it is fully mature at 3.5 days post-fertilization. Herein, we aimed to evaluate the usefulness of zebrafish larvae as a model of renal tubular toxicity through a comprehensive analysis of the renal alterations induced by the lethal concentrations for 10% of the larvae for gentamicin, paracetamol and tenofovir...
September 20, 2017: Archives of Toxicology
https://www.readbyqxmd.com/read/28932130/pulmonary-hypertension-due-to-lung-diseases-and-or-hypoxia-what-do-we-actually-know
#9
EDITORIAL
Djuro Kosanovic, Emilio A Herrera, Akylbek Sydykov, Stylianos E Orfanos, Elie El Agha
No abstract text is available yet for this article.
2017: Canadian Respiratory Journal: Journal of the Canadian Thoracic Society
https://www.readbyqxmd.com/read/28930826/infective-endocarditis-in-patients-with-cancer-a-consequence-of-invasive-procedures-or-a-harbinger-of-neoplasm-a-prospective-multicenter-cohort
#10
Ana Fernández-Cruz, Patricia Muñoz, Carmen Sandoval, Carmen Fariñas, Manuel Gutiérrez-Cuadra, Juan M Pericás Pulido, José M Miró, Miguel Á Goenaga-Sánchez, Arístides de Alarcón, Francisco Bonache-Bernal, MªÁngeles Rodríguez, Mariam Noureddine, Emilio Bouza Santiago
The aim of the study was to draw a comparison between the characteristics of infective endocarditis (IE) in patients with cancer and those of IE in noncancer patients.Patients with IE, according to the modified Duke criteria, were prospectively included in the GAMES registry between January 2008 and February 2014 in 30 hospitals. Patients with active cancer were compared with noncancer patients.During the study period, 161 episodes of IE fulfilled the inclusion criteria. We studied 2 populations: patients whose cancer was diagnosed before IE (73...
September 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28930197/red-blood-cell-eicosapentaenoic-acid-inversely-relates-to-mri-assessed-carotid-plaque-lipid-core-burden-in-elders-at-high-cardiovascular-risk
#11
Núria Bargalló, Rosa Gilabert, Edwin-Saúl Romero-Mamani, Montserrat Cofán, Philip C Calder, Montserrat Fitó, Dolores Corella, Jordi Salas-Salvadó, Miguel Ruiz-Canela, Ramon Estruch, Emilio Ros, Aleix Sala-Vila
Supplemental marine omega-3 eicosapentaenoic acid (EPA) has an anti-atherosclerotic effect. Clinical research on EPA supplied by the regular diet and atherosclerosis is scarce. In the framework of the PREvención con DIeta MEDiterránea (PREDIMED) trial, we conducted a cross-sectional study in 161 older individuals at high vascular risk grouped into different stages of carotid atherosclerosis severity, including those without ultrasound-detected atheroma plaque (n = 38), with plaques <2.0 mm thick (n = 65), and with plaques ≥2...
September 20, 2017: Nutrients
https://www.readbyqxmd.com/read/28927478/molecular-hydrogen-generated-by-elemental-magnesium-supplementation-alters-rumen-fermentation-and-microbiota-in-goats
#12
Min Wang, Rong Wang, XiuMin Zhang, Emilio M Ungerfeld, Donglei Long, HongXiang Mao, JinZhen Jiao, Karen A Beauchemin, Zhiliang Tan
We tested the hypotheses that supplementation of a diet with elemental Mg increases ruminal dissolved H2 (dH2) in rumen fluid, which in turn alters rumen fermentation and microbial community in goats. In a randomised block design, twenty growing goats were allocated to two treatments fed the same basal diet with 1·45 % Mg(OH)2 or 0·6 % elemental Mg. After 28 d of adaptation, we collected total faeces to measure total tract digestibility, rumen contents to analyse fermentation end products and microbial groups, and measured methane (CH4) emission using respiration chambers...
September 20, 2017: British Journal of Nutrition
https://www.readbyqxmd.com/read/28922667/integrated-strategy-for-mutagenicity-prediction-applied-to-food-contact-chemicals
#13
Serena Manganelli, Benoît Schilter, Emilio Benfenati, Alberto Manganaro, Elena Lo Piparo
Food contamination due to unintentional leakage of chemicals from food contact materials (FCM) is a source of increasing concern. Since for many of these substances, only limited or no toxicological data are available, the development of alternative methodologies to establish rapidly and cost-efficiently level of safety concern is critical to ensure adequate consumer protection. Computational toxicology methods are considered the most promising solutions to cope with this data gap. In particular, mutagenicity assessment has a particular relevance and is a mandatory requirement for all substances released from plastic FCM, regardless how low migration and exposure are...
September 18, 2017: ALTEX
https://www.readbyqxmd.com/read/28922488/isolation-of-rhodotorula-mucilaginosa-from-blood-cultures-in-a-tertiary-care-hospital
#14
Iker Falces-Romero, Emilio Cendejas-Bueno, María Pilar Romero-Gómez, Julio García-Rodríguez
BACKGROUND: Rhodotorula species have traditionally been considered as one of common non-virulent environmental inhabitant. They have emerged as an opportunistic pathogen, particularly in immunocompromised hosts and most infections have been associated with intravenous catheters in these patients. OBJECTIVE: We review the isolates in blood cultures of Rhodotorula mucilaginosa in our Hospital. We describe the demographic and clinical features of the cases and the antifungal susceptibility profiles of the isolates...
September 18, 2017: Mycoses
https://www.readbyqxmd.com/read/28921954/remote-late-stage-oxidation-of-aliphatic-c-h-bonds-in-amide-containing-molecules
#15
Takeshi Nanjo, Emilio Carlos de Lucca, M Christina White
Amide-containing molecules are ubiquitous in natural products, pharmaceuticals, and materials science. Due to their intermediate electron-richness, they are not amenable to any of the previously developed N-protection strategies known to enable remote aliphatic C-H oxidations. Using information gleaned from a systematic study of the main features that makes remote oxidations of amides in peptide settings possible, we developed an imidate salt protecting strategy that employs methyl trifluoromethanesulfonate (MeOTf) as a reversible alkylating agent...
September 18, 2017: Journal of the American Chemical Society
https://www.readbyqxmd.com/read/28918980/outcomes-of-aortic-valve-replacement-according-to-surgical-approach-in-intermediate-and-low-risk-patients-a-propensity-score-analysis
#16
Corazon M Calle-Valda, Rio Aguilar, Amparo Benedicto, Anas Sarraj, Emilio Monguio, Daniel Munoz, Nieves De Antonio, Guillermo Reyes
BACKGROUND: Previous trials have shown that, among high-risk patients with aortic stenosis, survival rates are similar for transcatheter aortic-valve implantation (TAVI) and surgical aortic valve replacement. The study aimed to compare the outcomes of aortic valve replacement according to the adopted surgical approach in intermediate and low risk patients. METHODS: This is a retrospective, observational, cohort study of prospectively collected data from 421 patients undergoing isolated aortic valve replacement between 2011 and 2015...
September 6, 2017: Heart, Lung & Circulation
https://www.readbyqxmd.com/read/28918337/ecotoxicological-and-microbiological-assessment-of-sewage-sludge-associated-with-sugarcane-bagasse
#17
Lais Roberta Deroldo Sommaggio, Dânia Elisa Christofoletti Mazzeo, Débora de Andrade E Silva Sant' Anna, Carlos Emílio Levy, Maria Aparecida Marin-Morales
Sewage sludge (SS) obtained after sewage treatment process may contain several toxic substances. Bioremediation can decrease the toxicity of the sludge, mainly when it is associated with stimulant agents, such as sugarcane bagasse (B). Samples of pure SS (SSP); SS+B; SS+Soil; and SS+B+Soil were bioremediated for 1, 3, and 6 months (T1, T2, and T3, respectively). After each period, the cytotoxic, genotoxic, and mutagenic potentials of the solid samples and their respective aqueous extracts (aqueous eluate and percolate water) were evaluated by the Allium cepa test...
September 14, 2017: Ecotoxicology and Environmental Safety
https://www.readbyqxmd.com/read/28912901/can-a-selective-serotonin-reuptake-inhibitor-act-as-a-glutamatergic-modulator
#18
Marcos Emilio Frizzo
Sertraline (Zoloft) and fluoxetine (Prozac) are selective serotonin reuptake inhibitors whose antidepressant mechanism of action is classically attributed to an elevation of the extracellular levels of serotonin in the synaptic cleft. However, the biological effects of these drugs seem to be more complex than their traditionally described mechanism of action. Among their actions is the inhibition of different types of Na(+) and K(+) channels, as well as of glutamate uptake activity. The clearance of extracellular glutamate is essential to maintain the central nervous system within physiological conditions, and this excitatory neurotransmitter is removed from the synaptic cleft by astrocyte transporters...
2017: Current Therapeutic Research, Clinical and Experimental
https://www.readbyqxmd.com/read/28912756/fixk2-is-the-main-transcriptional-activator-of-bradyrhizobium-diazoefficiens-nosrzdyflx-genes-in-response-to-low-oxygen
#19
María J Torres, Emilio Bueno, Andrea Jiménez-Leiva, Juan J Cabrera, Eulogio J Bedmar, Socorro Mesa, María J Delgado
The powerful greenhouse gas, nitrous oxide (N2O) has a strong potential to drive climate change. Soils are the major source of N2O and microbial nitrification and denitrification the main processes involved. The soybean endosymbiont Bradyrhizobium diazoefficiens is considered a model to study rhizobial denitrification, which depends on the napEDABC, nirK, norCBQD, and nosRZDYFLX genes. In this bacterium, the role of the regulatory cascade FixLJ-FixK2-NnrR in the expression of napEDABC, nirK, and norCBQD genes involved in N2O synthesis has been previously unraveled...
2017: Frontiers in Microbiology
https://www.readbyqxmd.com/read/28910345/circulating-mrnas-and-mirnas-as-candidate-markers-for-the-diagnosis-and-prognosis-of-prostate-cancer
#20
Marilesia Ferreira de Souza, Hellen Kuasne, Mateus de Camargo Barros-Filho, Heloísa Lizotti Cilião, Fabio Albuquerque Marchi, Paulo Emilio Fuganti, Alexandre Rossi Paschoal, Silvia Regina Rogatto, Ilce Mara de Syllos Cólus
Circulating nucleic acids are found in free form in body fluids and may serve as minimally invasive tools for cancer diagnosis and prognosis. Only a few studies have investigated the potential application of circulating mRNAs and microRNAs (miRNAs) in prostate cancer (PCa). The Cancer Genome Atlas (TCGA) database was used for an in silico analysis to identify circulating mRNA and miRNA as potential markers of PCa. A total of 2,267 genes and 49 miRNAs were differentially expressed between normal and tumor samples...
2017: PloS One
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