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Prenatal nutrition

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https://www.readbyqxmd.com/read/29447176/cost-effectiveness-of-prenatal-food-and-micronutrient-interventions-on-under-five-mortality-and-stunting-analysis-of-data-from-the-minimat-randomized-trial-bangladesh
#1
Pernilla Svefors, Katarina Ekholm Selling, Rubina Shaheen, Ashraful Islam Khan, Lars-Åke Persson, Lars Lindholm
INTRODUCTION: Nutrition interventions may have favourable as well as unfavourable effects. The Maternal and Infant Nutrition Interventions in Matlab (MINIMat), with early prenatal food and micronutrient supplementation, reduced infant mortality and were reported to be very cost-effective. However, the multiple micronutrients (MMS) supplement was associated with an increased risk of stunted growth in infancy and early childhood. This unfavourable outcome was not included in the previous cost-effectiveness analysis...
2018: PloS One
https://www.readbyqxmd.com/read/29447091/obesity-in-pregnancy-a-comparison-of-four-national-guidelines
#2
Dana Vitner, Kristin Harris, Cynthia Maxwell, M D Farine
BACKGROUND: Obesity in pregnancy has become one of the most important challenges in obstetrical care given its prevalence and potential adverse impact on both mother and fetus. The primary objective of this descriptive review is to identify common themes and distinctions within the current recommendations for maternal obesity in the most updated version of four published national guidelines. METHODS: We reviewed the following guidelines for obesity in pregnancy: American College of Obstetricians and Gynecologists (ACOG) 2015, Royal Australian and New Zealand College of Obstetricians and Gynecologists (RANZCOG) 2013, Royal College of Obstetrics and Gynecology (RCOG) 2010, and Society of Obstetrics and Gynecologists of Canada (SOGC) 2010...
February 15, 2018: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/29442995/maternal-characteristics-of-prenatal-wic-receipt-in-the-united-states-2016
#3
Anne K Driscoll, Michelle J K Osterman
Four in 10 women (39.6%) who gave birth in the United States in 2016 received prenatal benefits from the Special Supplemental Nutrition Program for Women, Infants,and Children (WIC).Rates of prenatal WIC receipt declined with increasing maternal age for women under 40. Among the six race and Hispanic-origin groups, receipt of prenatal WIC was highest for Hispanic mothers (61.4%) and lowest for non-Hispanic Asian mothers (23.2%).Receipt of prenatal WIC decreased as maternal education level increased.
January 2018: NCHS Data Brief
https://www.readbyqxmd.com/read/29439389/early-life-exposure-to-non-nutritive-sweeteners-and-the-developmental-origins-of-childhood-obesity-global-evidence-from-human-and-rodent-studies
#4
REVIEW
Alyssa J Archibald, Vernon W Dolinsky, Meghan B Azad
Non-nutritive sweeteners (NNS) are increasingly consumed by children and pregnant women around the world, yet their long-term health impact is unclear. Here, we review an emerging body of evidence suggesting that early-life exposure to NNS may adversely affect body composition and cardio-metabolic health. Some observational studies suggest that children consuming NNS are at increased risk for obesity-related outcomes; however, others find no association or provide evidence of confounding. Fewer studies have examined prenatal NNS exposure, with mixed results from different analytical approaches...
February 10, 2018: Nutrients
https://www.readbyqxmd.com/read/29419329/understanding-gastroschisis-and-its-clinical-management-where-are-we
#5
Candace Haddock, Erik D Skarsgard
Gastroschisis is the commonest developmental defect of the anterior abdominal wall in both developed and developing countries. The past 30 years have seen transformational improvements in outcome due to advances in neonatal intensive care and enhanced integration between the disciplines of maternal fetal medicine, neonatology and pediatric surgery. A review of gastroschisis, which emphasizes its epidemiology, multidisciplinary care strategies and contemporary outcomes is timely. Areas covered: This review discusses the current state of knowledge related to prevalence and causation, and postulated embryopathologic mechanisms contributing to the development of gastroschisis...
February 8, 2018: Expert Review of Gastroenterology & Hepatology
https://www.readbyqxmd.com/read/29417365/integrating-obstetrical-care-and-wic-nutritional-services-to-address-maternal-obesity-and-postpartum-weight-retention
#6
Susan M Gross, Marycatherine Augustyn, Janice L Henderson, Khrysta Baig, Christie A Williams, Bolanle Ajao, Patricia Bell-Waddy, David M Paige
OBJECTIVE: This pilot study evaluated a cost neutral, integrated Special Supplemental Nutrition Program for Women Infants and Children (WIC) and obstetrical service model designed to prevent postpartum weight retention in obese women. METHODS: A sample of women who received benefits from the Johns Hopkins (JH) WIC program and prenatal care from the JH Nutrition in Pregnancy Clinic, which provides obstetrical care for women with a BMI ≥ 30 kg/m2, participated in the WICNIP randomized clinical trial...
February 7, 2018: Maternal and Child Health Journal
https://www.readbyqxmd.com/read/29415730/effect-of-nutrient-supplementation-on-the-acquisition-of-humoral-immunity-to-plasmodium-falciparum-in-young-malawian-children
#7
Priyanka Barua, Upeksha P Chandrasiri, James G Beeson, Kathryn G Dewey, Kenneth Maleta, Per Ashorn, Stephen J Rogerson
BACKGROUND: There is evidence that suggests that undernutrition has a detrimental effect on malarial immunity in children. The aim of the study was to discover whether nutrient supplementation improved development of malarial antibody immunity in children up to 18 months of age. METHODS: The study was conducted with a subset of 432 Malawian children from a randomized controlled trial of nutritional supplements. The arms included pre- and postnatal small-quantity lipid-based nutrient supplements for both mother and child; prenatal supplementation with iron and folic acid; and pre- and postnatal supplementation with multiple micronutrients...
February 7, 2018: Malaria Journal
https://www.readbyqxmd.com/read/29412180/as-you-eat-it-effects-of-prenatal-nutrition-on-asthma
#8
Kathleen Lee-Sarwar, Augusto A Litonjua
Asthma most frequently develops early in life, and increased recognition of the role of lifestyle and environmental factors in asthma susceptibility raises the possibility that dietary exposures during pregnancy may influence risk of asthma in offspring. This review discusses the latest evidence with regard to the effect of diet during pregnancy on childhood asthma risk, including potential mechanisms, outcomes of randomized clinical trials, and results from observational studies. Vitamin D and polyunsaturated fatty acid intake during pregnancy are highlighted as areas with large and growing bodies of literature to support a potential role in prenatal modulation of subsequent asthma risk...
February 2, 2018: Journal of Allergy and Clinical Immunology in Practice
https://www.readbyqxmd.com/read/29412146/predictive-factors-for-birth-weight-of-newborns-of-mothers-with-gestational-diabetes-mellitus
#9
Sara de Oliveira Corrêa da Silva, Cláudia Saunders, Lenita Zajdenverg, Luciana Novaes Moreira, Sonaly Petronilho Heidelmann, Ariane Cristine Dos Santos Pereira, Patricia de Carvalho Padilha
AIMS: To evaluate the predictive factors of birth weight (BW) of newborns of women with gestational diabetes mellitus (GDM). METHODS: A cross-sectional study was performed among pregnant women with GDM treated in a public maternity unit, Brazil. We selected 283 pregnant women, with nutritional follow-up initiated till the 28th gestational week, singleton pregnancy, without chronic diseases and with birth weight information of the newborns. The predictive factors of BW were identified by multivariate linear regression...
February 2, 2018: Diabetes Research and Clinical Practice
https://www.readbyqxmd.com/read/29396029/prenatal-treatment-of-ornithine-transcarbamylase-deficiency
#10
Yael Wilnai, Yair J Blumenfeld, Kristina Cusmano, Susan R Hintz, Deborah Alcorn, William E Benitz, William E Berquist, Jonathan A Bernstein, Ricardo O Castillo, Waldo Concepcion, Tina M Cowan, Kenneth L Cox, Deirdre J Lyell, Carlos O Esquivel, Margaret Homeyer, Louanne Hudgins, Melissa Hurwitz, Jonathan P Palma, Susan Schelley, Vishnu Priya Akula, Marshall L Summar, Gregory M Enns
PURPOSE OF STUDY: Patients with neonatal urea cycle defects (UCDs) typically experience severe hyperammonemia during the first days of life, which results in serious neurological injury or death. Long-term prognosis despite optimal pharmacological and dietary therapy is still poor. The combination of intravenous sodium phenylacetate and sodium benzoate (Ammonul®) can eliminate nitrogen waste independent of the urea cycle. We report attempts to improve outcomes for males with severe ornithine transcarbamylase deficiency (OTCD), a severe X-linked condition, via prenatal intravenous administration of Ammonul and arginine to heterozygous carrier females of OTCD during labor...
January 16, 2018: Molecular Genetics and Metabolism
https://www.readbyqxmd.com/read/29392771/the-redistribution-of-reproductive-responsibility-on-the-epigenetics-of-environment-in-prenatal-interventions
#11
Natali Valdez
The rapidly shifting field of epigenetics has expanded scientific understanding of how environmental conditions affect gene expression and development. This article focuses on two ongoing clinical trials-one in the United States and one in the United Kingdom-that have used epigenetics as the conceptual basis for testing the relationship between nutrition and obesity during pregnancy. Drawing on ethnographic research, I highlight the different ways that clinical scientists interpret epigenetics to target particular domains of the environment for prenatal intervention...
February 1, 2018: Medical Anthropology Quarterly
https://www.readbyqxmd.com/read/29385480/genotype-x-prenatal-and-post-weaning-nutritional-environment-interaction-in-a-composite-beef-cattle-breed-using-reaction-norms-and-a-multi-trait-model
#12
El Hamidi Hay, Andy Roberts
Environmental effects have been shown to influence several economically important traits in beef cattle. In this study, genotype x nutritional environment interaction has been evaluated in a composite beef cattle breed (50% Red Angus, 25% Charolais, 25% Tarentaise). Four nutritional environments (MARG-RES, MARG-CTRL, ADEQ-RES and ADEQ-CTRL) were created based on 2 levels of winter supplement provided to dams grazing winter range during gestation (MARG and ADEQ) and 2 levels of input to offspring during post-weaning development (RES and CTRL)...
January 29, 2018: Journal of Animal Science
https://www.readbyqxmd.com/read/29380331/neuropsychiatric-sequelae-of-early-nutritional-modifications-a-beginner-s-guide-to-behavioral-analysis
#13
Ann-Katrin Kraeuter, Paul C Guest, Zoltán Sarnyai
Early parental nutritional interventions during prenatal development have been shown to result in neuropsychiatric sequelae in the adult offspring. In order to understand the impact of such nutritional interventions, the behavior of the animal has to be carefully analyzed. This chapter provides a step-by-step guide to conduct behavioral tests in adult mice for investigators without specific expertise or those without the equipment to carry out behavioral studies. We focus on tests tapping into the main behavioral abnormalities that correspond to mental illnesses...
2018: Methods in Molecular Biology
https://www.readbyqxmd.com/read/29380305/effects-of-prenatal-nutrition-and-the-role-of-the-placenta-in-health-and-disease
#14
Leslie Myatt, Kent L Thornburg
Epidemiologic studies identified the linkage between exposures to stresses, including the type and plane of nutrition in utero with development of disease in later life. Given the critical roles of the placenta in mediating transport of nutrients between the mother and fetus and regulation of maternal metabolism, recent attention has focused on the role of the placenta in mediating the effect of altered nutritional exposures on the development of disease in later life. In this chapter we describe the mechanisms of nutrient transport in the placenta, the influence of placental metabolism on this, and how placental energetics influence placental function in response to a variety of stressors...
2018: Methods in Molecular Biology
https://www.readbyqxmd.com/read/29370535/effects-of-prenatal-alcohol-exposure-pae-insights-into-fasd-using-pae-mouse-models
#15
Berardino Petrelli, Joanne Weinberg, Geoffrey G Hicks
The potential impact of prenatal alcohol exposure (PAE) varies considerably among exposed individuals, with some displaying serious alcohol-related effects and others showing few or even no overt signs of a fetal alcohol spectrum disorder (FASD). In animal models variables such as nutrition, genetic background, health, other drugs, and stress, as well as dosage, duration and gestational timing of alcohol exposure can all be controlled in a way not possible in a clinical situation. In this review we examine mouse PAE models and focus on those with demonstrated craniofacial malformations, abnormal brain development, or behavioural phenotypes that may be considered FASD-like outcomes...
January 25, 2018: Biochemistry and Cell Biology, Biochimie et Biologie Cellulaire
https://www.readbyqxmd.com/read/29370250/associations-of-psychosocial-factors-with-pregnancy-healthy-life-styles
#16
Shabnam Omidvar, Mahbobeh Faramarzi, Karimallah Hajian-Tilak, Fatemeh Nasiri Amiri
Healthy behaviors in pregnant women have a major effect on pregnancy outcomes; however, only few studies have explored the relationship of multiple psychosocial factors with healthy lifestyles during pregnancy. The objective of this study was to investigate whether the five psychosocial factors of anxiety, stress, depression, marital dissatisfaction, and social support are associated with six domains of healthy lifestyles in pregnant women, including nutrition, physical activity, health responsibility, stress management, interpersonal relationships, and self-actualization...
2018: PloS One
https://www.readbyqxmd.com/read/29364360/novel-multidisciplinary-approach-to-monitor-and-treat-fetuses-with-gastroschisis-using-the-svetliza-reducibility-index-and-the-exit-like-procedure
#17
Gustavo Henrique de Oliveira, Javier Svetliza, Denise Cristina Mós Vaz-Oliani, Humberto Liedtke Junior, Antonio Helio Oliani, Denise Araujo Lapa Pedreira
OBJECTIVE: To describe our initial experience with a novel approach to follow-up and treat gastroschisis in "zero minute" using the EXITlike procedure. METHODS: Eleven fetuses with prenatal diagnosis of gastroschisis were evaluated. The Svetliza Reductibility Index was used to prospectively evaluate five cases, and six cases were used as historical controls. The Svetliza Reductibility Index consisted in dividing the real abdominal wall defect diameter by the larger intestinal loop to be fitted in such space...
October 2017: Einstein
https://www.readbyqxmd.com/read/29358479/advocacy-for-improving-nutrition-in-the-first-1000-days-to-support-childhood-development-and-adult-health
#18
Sarah Jane Schwarzenberg, Michael K Georgieff
Maternal prenatal nutrition and the child's nutrition in the first 2 years of life (1000 days) are crucial factors in a child's neurodevelopment and lifelong mental health. Child and adult health risks, including obesity, hypertension, and diabetes, may be programmed by nutritional status during this period. Calories are essential for growth of both fetus and child but are not sufficient for normal brain development. Although all nutrients are necessary for brain growth, key nutrients that support neurodevelopment include protein; zinc; iron; choline; folate; iodine; vitamins A, D, B6, and B12; and long-chain polyunsaturated fatty acids...
January 22, 2018: Pediatrics
https://www.readbyqxmd.com/read/29355495/endocrine-active-metals-prenatal-stress-and-enhanced-neurobehavioral-disruption
#19
Marissa Sobolewski, Katherine Conrad, Elena Marvin, Joshua L Allen, Deborah A Cory-Slechta
Metals, including lead (Pb), methylmercury (MeHg) and arsenic (As), are long-known developmental neurotoxicants. More recently, environmental context has been recognized to modulate metals toxicity, including nutritional state and stress exposure. Modulation of metal toxicity by stress exposure can occur through shared targeting of endocrine systems, such as the hypothalamic-pituitary-adrenal axis (HPA). Our previous rodent research has identified that prenatal stress (PS) modulates neurotoxicity of two endocrine active metals (EAMs), Pb and MeHg, by altering HPA and CNS systems disrupting behavior...
January 17, 2018: Hormones and Behavior
https://www.readbyqxmd.com/read/29351580/maternal-nutrient-restriction-impairs-young-adult-offspring-ovarian-signaling-resulting-in-reproductive-dysfunction-and-follicle-loss
#20
K A Chan, P A Jazwiec, W Gohir, J J Petrik, D M Sloboda
Reproductive abnormalities are included as health complications in offspring exposed to poor prenatal nutrition. We have previously shown in a rodent model, that offspring born to nutrient restriction during pregnancy are born small, enter puberty early, and display characteristics of early ovarian aging as adults. The present study investigated whether key proteins involved in follicle recruitment and growth mediate ovarian follicle loss. Pregnant rats were randomized to: a standard diet throughout pregnancy and lactation (CON), or a calorie-restricted (50% of control) diet (UN) during pregnancy...
January 17, 2018: Biology of Reproduction
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